Home Other Building Blocks 364042-47-7
364042-47-7,MFCD28155266
Catalog No.:AA00C6BC

364042-47-7 | Rk 20449

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$116.00   $81.00
- +
5mg
≥98%
in stock  
$285.00   $199.00
- +
10mg
≥98%
in stock  
$509.00   $356.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C6BC
Chemical Name:
Rk 20449
CAS Number:
364042-47-7
Molecular Formula:
C29H34N6O
Molecular Weight:
482.6199
MDL Number:
MFCD28155266
SMILES:
CN1CCN(CC1)C1CCC(CC1)n1cc(c2c1ncnc2N)c1ccc(cc1)Oc1ccccc1
Properties
Computed Properties
 
Complexity:
679  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
4.5  

Literature

Title: Wilson MB, et al. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis. Oncogene. 2002 Nov 21;21(53):8075-88.

Title: Pene-Dumitrescu T, et al. An inhibitor-resistant mutant of Hck protects CML cells against the antiproliferative and apoptotic effects of the broad-spectrum Src family kinase inhibitor A-419259.Oncogene (2008) 27, 7055-7069

Title: Anthony Cheung, et al. Anti-Folate Receptor Alpha-Directed Antibody Therapies Restrict the Growth of Triple-negative Breast Cancer. Clin Cancer Res. 2018 Oct 15;24(20):5098-5111.

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SDS
Tags:364042-47-7 Molecular Formula|364042-47-7 MDL|364042-47-7 SMILES|364042-47-7 Rk 20449