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Title: Blockade of the extracellular signal-regulated kinase pathway enhances the therapeutic efficacy of microtubule-destabilizing agents in human tumor xenograft models.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100215
Title: Efficacy of selected natural products as therapeutic agents against cancer.
Journal: Journal of natural products 20080301
Title: Comparison of the antivascular and cytotoxic activities of TZT-1027 (Soblidotin) with those of other anticancer agents.
Journal: Anti-cancer drugs 20070901
Title: Glaziovianin A, a new isoflavone, from the leaves of Ateleia glazioviana and its cytotoxic activity against human cancer cells.
Journal: Bioorganic & medicinal chemistry letters 20070601
Title: The novel microtubule-interfering agent TZT-1027 enhances the anticancer effect of radiation in vitro and in vivo.
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Title: Vascular disrupting agents in clinical development.
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Title: Tumor-specific antivascular effect of TZT-1027 (Soblidotin) elucidated by magnetic resonance imaging and confocal laser scanning microscopy.
Journal: Cancer science 20070401
Title: The inhibitory effect of docetaxel and p38 MAPK inhibitor on TZT-1027 (Soblidotin)-induced antivascular activity.
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Title: Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates.
Journal: The Journal of biological chemistry 20060414
Title: Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates.
Journal: Cancer research 20060215
Title: Reference profiling of the genomic response induced by an antimicrotubule agent, TZT-1027 (Soblidotin), in vitro.
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Title: Combination effect of TZT-1027 (Soblidotin) with other anticancer drugs.
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Title: Total assignment of the (1)H- and (13)C-NMR spectra for TZT-1027 and related compounds.
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Title: [Structure-activity relationship analysis].
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Title: TZT-1027 elucidates antitumor activity through direct cytotoxicity and selective blockade of blood supply.
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Title: Antitumor activity of TZT-1027 (Soblidotin) against vascular endothelial growth factor-secreting human lung cancer in vivo.
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Title: Enhanced antitumor activities of TZT-1027 against TNF-alpha or IL-6 secreting Lewis lung carcinoma in vivo.
Journal: Cancer chemotherapy and pharmacology 20020101
Title: Validation of an analytical method for a potent antitumor agent, TZT-1027, in plasma using liquid chromatography-mass spectrometry.
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