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40296-46-6,MFCD00234408
Catalog No.:AA0034SB

40296-46-6 | Ethyl 4,6-dichloronicotinate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$11.00   $8.00
- +
5g
98%
in stock  
$17.00   $12.00
- +
10g
98%
in stock  
$22.00   $15.00
- +
25g
98%
in stock  
$27.00   $19.00
- +
100g
98%
in stock  
$106.00   $75.00
- +
500g
98%
in stock  
$529.00   $370.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0034SB
Chemical Name:
Ethyl 4,6-dichloronicotinate
CAS Number:
40296-46-6
Molecular Formula:
C8H7Cl2NO2
Molecular Weight:
220.0527
MDL Number:
MFCD00234408
SMILES:
CCOC(=O)c1cnc(cc1Cl)Cl
Properties
Properties
 
BP:
276.3°C at 760 mmHg  
Form:
Liquid  
MP:
32 - 32.5 °C  
Solubility:
Soluble in methanol.  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
189  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
2.7  

Upstream Synthesis Route

[1]RecueildesTravauxChimiquesdesPays-Bas,1950,vol.69,p.673,690

[1]RecueildesTravauxChimiquesdesPays-Bas,1950,vol.69,p.673,690

[1]RecueildesTravauxChimiquesdesPays-Bas,1950,vol.69,p.673,690

[1]RecueildesTravauxChimiquesdesPays-Bas,1950,vol.69,p.673,690

[1]Patent:US2005/49419,2005,A1,.Locationinpatent:Page/Pagecolumn24

[2]Patent:US2005/54701,2005,A1,

[3]TetrahedronLetters,2011,vol.52,#4,p.512-514

[4]Patent:WO2014/52365,2014,A1,.Locationinpatent:Page/Pagecolumn229-230

[5]Patent:US2015/191464,2015,A1,.Locationinpatent:Paragraph0611

[6]Patent:WO2016/210036,2016,A1,.Locationinpatent:Page/Pagecolumn62;63

[7]AntimicrobialAgentsandChemotherapy,2016,vol.60,#8,p.4442-4452

[8]Patent:US2012/108566,2012,A1,.Locationinpatent:Page/Pagecolumn55

[9]RecueildesTravauxChimiquesdesPays-Bas,1950,vol.69,p.673,690

[10]Patent:WO2014/74675,2014,A1,.Locationinpatent:Paragraph00185;00196

[11]Patent:WO2014/74657,2014,A1,.Locationinpatent:Paragraph00146

[12]Patent:JP2015/124211,2015,A,.Locationinpatent:Paragraph0167

Downstream Synthesis Route

[1]AsianJournalofChemistry,2019,vol.31,p.627-632

[2]Patent:CN106810558,2017,A.Locationinpatent:Paragraph0158;0160;0161

[3]Patent:CN106810559,2017,A.Locationinpatent:Paragraph0162;0167-0169

[4]Patent:CN110272415,2019,A.Locationinpatent:Paragraph0069;0072;0083-0085

[5]Patent:WO2008/30266,2008,A2.Locationinpatent:Page/Pagecolumn32

[6]Patent:US2008/108667,2008,A1.Locationinpatent:Page/Pagecolumn13

[1]Patent:WO2008/16643,2008,A2.Locationinpatent:Page/Pagecolumn329

[1]CurrentPatentAssignee:YANGTZERIVERPHARMACEUTICALGROUPCOLTD-US2021/386721,2021,A1Locationinpatent:Paragraph0234-0235

[2]CurrentPatentAssignee:YANGTZERIVERPHARMACEUTICALGROUPCOLTD-US2021/386721,2021,A1Locationinpatent:Paragraph0234-0235

[3]Montoir,David;Tonnerre,Alain;Duflos,Muriel;Bazin,Marc-Antoine[EuropeanJournalofOrganicChemistry,2014,vol.2014,#7,p.1487-1495]

[4]Montoir,David;Tonnerre,Alain;Duflos,Muriel;Bazin,Marc-Antoine[EuropeanJournalofOrganicChemistry,2014,vol.2014,#7,p.1487-1495]

[5]Montoir,David;Barillé-Nion,Sophie;Tonnerre,Alain;Juin,Philippe;Duflos,Muriel;Bazin,Marc-Antoine[EuropeanJournalofMedicinalChemistry,2016,vol.119,p.17-33]

[6]CurrentPatentAssignee:DECIPHERAPHARMACEUTICALSLLC-WO2013/184119,2013,A1Locationinpatent:Paragraph0194

[7]CurrentPatentAssignee:THEUNIVERSITYOFHOUSTONSYSTEM;TRUSTEESOFTUFTSCOLLEGE,INC.-WO2018/213219,2018,A1Locationinpatent:Paragraph0263-0264;0021

[8]CurrentPatentAssignee:FOXCHASECANCERCENTER;TRUSTEESOFTUFTSCOLLEGE,INC.;INSTITUTEFORCANCERRESDBATHERESINTITUTEOFFOXCHASECANCERCENTER;THEUNIVERSITYOFHOUSTONSYSTEM-WO2020/232190,2020,A1Locationinpatent:Paragraph0087-0089;0323-0324

[9]CurrentPatentAssignee:ELILILLY&CO-WO2018/111707,2018,A1Locationinpatent:Page/Pagecolumn54

[10]CurrentPatentAssignee:DECIPHERAPHARMACEUTICALSLLC-WO2008/33999,2008,A2Locationinpatent:Page/Pagecolumn88

[11]CurrentPatentAssignee:IRMLLC-WO2008/51757,2008,A1Locationinpatent:Page/Pagecolumn31;32

[12]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2011/97526,2011,A1Locationinpatent:Page/Pagecolumn30-31

[13]CurrentPatentAssignee:DECIPHERAPHARMACEUTICALSLLC-US8461179,2013,B1Locationinpatent:Page/Pagecolumn64

[14]CurrentPatentAssignee:INCYTECORP-US2014/315902,2014,A1Locationinpatent:Paragraph0263;0264

[15]CurrentPatentAssignee:IRMLLC-WO2009/105712,2009,A1Locationinpatent:Page/Pagecolumn35-36

[16]CurrentPatentAssignee:IRMLLC-WO2005/34869,2005,A2Locationinpatent:Page/Pagecolumn40

[1]JournalofMedicinalChemistry,2007,vol.50,p.5090-5102

[2]Patent:WO2005/818,2005,A1.Locationinpatent:Page91

Literature
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SDS
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