Home Other Building Blocks 1643125-33-0
1643125-33-0,MFCD31619236
Catalog No.:AA01EO7P

1643125-33-0 | SAFit2

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$348.00   $243.00
- +
5mg
98% by HPLC
in stock  
$361.00   $253.00
- +
10mg
98% by HPLC
in stock  
$566.00   $396.00
- +
25mg
98% by HPLC
in stock  
$1,127.00   $789.00
- +
50mg
98% by HPLC
in stock  
$1,875.00   $1,313.00
- +
100mg
98% by HPLC
in stock  
$3,199.00   $2,239.00
- +
500mg
98% by HPLC
in stock  
$10,187.00   $7,131.00
- +
1000mg
98% by HPLC
in stock  
$16,264.00   $11,385.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO7P
Chemical Name:
SAFit2
CAS Number:
1643125-33-0
Molecular Formula:
C46H62N2O10
Molecular Weight:
802.9919
MDL Number:
MFCD31619236
SMILES:
COc1cc(CC[C@H](c2cccc(c2)OCCN2CCOCC2)OC(=O)[C@@H]2CCCCN2C(=O)[C@H](c2cc(OC)c(c(c2)OC)OC)C2CCCCC2)ccc1OC
Properties
Computed Properties
 
Complexity:
1200  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
58  
Hydrogen Bond Acceptor Count:
11  
Rotatable Bond Count:
19  
XLogP3:
8.2  

Literature

Title: Gaali S, et al. Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. J Med Chem. 2016 Mar 24;59(6):2410-22.

Title: Balsevich G, et al. Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. Nat Commun. 2017 Nov 23;8(1):1725.

Title: Hartmann J, et al. Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties. J Neurosci. 2015 Jun 17;35(24):9007-16.

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SDS
Tags:1643125-33-0 Molecular Formula|1643125-33-0 MDL|1643125-33-0 SMILES|1643125-33-0 SAFit2