+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Carboxes 16732-57-3
16732-57-3,MFCD00216477
Catalog No.:AA001X85

16732-57-3 | Ethyl 5-nitroindole-2-carboxylate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$6.00   $4.00
- +
1g
98%
in stock  
$15.00   $11.00
- +
5g
98%
in stock  
$33.00   $23.00
- +
10g
98%
in stock  
$39.00   $28.00
- +
25g
98%
in stock  
$97.00   $68.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001X85
Chemical Name:
Ethyl 5-nitroindole-2-carboxylate
CAS Number:
16732-57-3
Molecular Formula:
C11H10N2O4
Molecular Weight:
234.2081
MDL Number:
MFCD00216477
SMILES:
CCOC(=O)c1cc2c([nH]1)ccc(c2)[N+](=O)[O-]
NSC Number:
131897
Properties
Properties
 
BP:
429.5 °C at 760 mmHg  
Form:
Solid  
MP:
220-225 °C  
Refractive Index:
1.5300 (estimate)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
315  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3  

Upstream Synthesis Route

[1]Farmaco,EdizioneScientifica,1958,vol.13,p.105,109

[1]Patent:WO2009/118411,2009,A2,.Locationinpatent:Page/Pagecolumn37

[2]Patent:WO2004/56768,2004,A2,.Locationinpatent:Page31;78

[3]Patent:WO2006/10008,2006,A1,.Locationinpatent:Page/Pagecolumn221

[4]Patent:WO2006/40180,2006,A1,.Locationinpatent:Page/Pagecolumn99

[5]Patent:US9226970,2016,B2,.Locationinpatent:Page/Pagecolumn40

[6]JournalofMedicinalChemistry,2012,vol.55,#2,p.766-782

[7]Patent:US5475092,1995,A,

[8]Patent:CN105820104,2016,A,.Locationinpatent:Paragraph0051;0053

[9]JournaloftheAmericanChemicalSociety,1958,vol.80,p.4621

[10]Farmaco,EdizioneScientifica,1958,vol.13,p.105,109

[11]TetrahedronLetters,2000,vol.41,#14,p.2443-2446

[12]JournaloftheAmericanChemicalSociety,2006,vol.128,#37,p.12162-12168

[13]BioorganicandMedicinalChemistryLetters,2010,vol.20,#9,p.2722-2725

[1]Patent:US6534660,2003,B1,

[1]Patent:CN107739368,2018,A,.Locationinpatent:Paragraph0036;0038;0040

[2]Synthesis,1980,#3,p.222-223

[3]Patent:US9226970,2016,B2,.Locationinpatent:Page/Pagecolumn39

[4]JournaloftheAmericanChemicalSociety,1958,vol.80,p.4621

[5]Farmaco,EdizioneScientifica,1958,vol.13,p.105,109

[6]BioorganicandMedicinalChemistryLetters,2008,vol.18,#14,p.4124-4129

[1]JournaloftheBrazilianChemicalSociety,2011,vol.22,#11,p.2036-2039

Downstream Synthesis Route

[1]Patent:WO2009/118411,2009,A2.Locationinpatent:Page/Pagecolumn37

[2]Patent:WO2004/56768,2004,A2.Locationinpatent:Page31;78

[3]Patent:WO2006/10008,2006,A1.Locationinpatent:Page/Pagecolumn221

[4]Patent:WO2006/40180,2006,A1.Locationinpatent:Page/Pagecolumn99

[5]Patent:US9226970,2016,B2.Locationinpatent:Page/Pagecolumn40

[6]JournalofMedicinalChemistry,2012,vol.55,p.766-782

[7]Patent:US5475092,1995,A

[8]Patent:CN105820104,2016,A.Locationinpatent:Paragraph0051;0053

[9]JournaloftheAmericanChemicalSociety,1958,vol.80,p.4621

[10]TetrahedronLetters,2000,vol.41,p.2443-2446

[11]JournaloftheAmericanChemicalSociety,2006,vol.128,p.12162-12168

[12]BioorganicandMedicinalChemistryLetters,2010,vol.20,p.2722-2725

[1]Patent:WO2005/80367,2005,A1.Locationinpatent:Page/Pagecolumn67-68;113-114

[2]Patent:WO2004/56768,2004,A2.Locationinpatent:Page88

[3]Patent:EP2876105,2015,A1.Locationinpatent:Paragraph0285;0286

[4]Patent:JP2015/13821,2015,A.Locationinpatent:Paragraph0165-0166

[5]Patent:US2010/145036,2010,A1.Locationinpatent:Page/Pagecolumn62;64

[6]JournalofMedicinalChemistry,2012,vol.55,p.766-782

[7]Patent:WO2008/103693,2008,A2.Locationinpatent:Page/Pagecolumn85

[8]Patent:US2006/160855,2006,A1.Locationinpatent:Page/Pagecolumn12-13

[9]Patent:US2005/26987,2005,A1.Locationinpatent:Page23

[10]JournalofHeterocyclicChemistry,1989,vol.26,p.557-564

[11]Patent:US6534660,2003,B1

[12]JournalofMedicinalChemistry,2009,vol.52,p.3855-3868

[13]ChemicalBiologyandDrugDesign,2016,p.766-778

[14]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1983,vol.22,p.1205-1208

[15]Patent:CN107739368,2018,A.Locationinpatent:Paragraph0036;0037;0038;0041

[16]Patent:CN104829597,2018,B.Locationinpatent:Paragraph0040;0041

[17]Patent:CN104860866,2018,B.Locationinpatent:Paragraph0035-0036

[18]Patent:CN109734708,2019,A.Locationinpatent:Paragraph0064;0066;0069

[19]BioorganicandMedicinalChemistryLetters,2010,vol.20,p.2722-2725

[20]Patent:US2003/78251,2003,A1

[21]Patent:WO2008/154271,2008,A1.Locationinpatent:Page/Pagecolumn122

[22]TetrahedronLetters,1986,vol.27,p.4103-4106

[23]BioorganicandMedicinalChemistry,2003,vol.11,p.1569-1575

[24]EuropeanJournalofOrganicChemistry,2006,p.2314-2321

[25]JournalofMedicinalChemistry,2000,vol.43,p.1541-1549

[26]Patent:US2003/195201,2003,A1

[27]Patent:US6387896,2002,B1

[28]Patent:US5866589,1999,A

[29]Patent:EP1731519,2006,A1.Locationinpatent:Page/Pagecolumn10;13

[30]Patent:US2007/232605,2007,A1.Locationinpatent:Page/Pagecolumn9

[31]Patent:US2007/225284,2007,A1.Locationinpatent:Page/Pagecolumn9

[32]Patent:US2004/63645,2004,A1.Locationinpatent:Page/Pagecolumn33;48

[33]Patent:WO2005/66180,2005,A1.Locationinpatent:Page/Pagecolumn83-84

[34]Patent:WO2007/6714,2007,A1.Locationinpatent:Page/Pagecolumn102

[35]Patent:WO2007/89149,2007,A2.Locationinpatent:Page/Pagecolumn102

[36]Patent:WO2016/1485,2016,A1.Locationinpatent:Page/Pagecolumn138

[37]Patent:US9226970,2016,B2.Locationinpatent:Page/Pagecolumn43

[38]EuropeanJournalofMedicinalChemistry,2019,vol.167,p.269-290

16732-57-3    1996-44-7   
3-(2,4-difluoro-phenylsulfanyl)-5-nitro-1<i>H</i>-indole-2-carboxylicacidethylester 

[1]TetrahedronLetters,2004,vol.45,p.4073-4075

[1]CurrentPatentAssignee:PFIZERINC-WO2005/30715,2005,A1Locationinpatent:Page/Pagecolumn40

[2]CurrentPatentAssignee:PFIZERINC-WO2005/30756,2005,A1Locationinpatent:Page/Pagecolumn39

[1]Patent:US6534660,2003,B1

Literature
Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 16732-57-3
147539-80-8

147539-80-8

 138731-14-3

138731-14-3

 16382-15-3

16382-15-3

 71086-99-2

71086-99-2

 16792-45-3

16792-45-3

 16730-20-4

16730-20-4
Building Blocks
More >
Tags:16732-57-3 Molecular Formula|16732-57-3 MDL|16732-57-3 SMILES|16732-57-3 Ethyl 5-nitroindole-2-carboxylate |Heterocyclic_Building_Blocks