[1]CurrentPatentAssignee:PFIZERINC-WO2007/126841,2007,A2Locationinpatent:Page/Pagecolumn82
[2]CurrentPatentAssignee:PFIZERINC-WO2009/62118,2009,A2Locationinpatent:Page/Pagecolumn180
[1]CurrentPatentAssignee:PFIZERINC-WO2009/62118,2009,A2Locationinpatent:Page/Pagecolumn214-215
[1]CurrentPatentAssignee:PFIZERINC-WO2009/62118,2009,A2Locationinpatent:Page/Pagecolumn208
[1]CurrentPatentAssignee:PFIZERINC-WO2009/62118,2009,A2Locationinpatent:Page/Pagecolumn219
[1]CurrentPatentAssignee:PFIZERINC-WO2009/62118,2009,A2Locationinpatent:Page/Pagecolumn232-233
Title: Silicon dioxide nanoparticles induce COX-2 expression through activation of STAT3 signaling pathway in HaCaT cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20181001
Title: Hexachlorobenzene alters cell cycle by regulating p27-cyclin E-CDK2 and c-Src-p27 protein complexes.
Journal: Toxicology letters 20170315
Title: Hexachlorobenzene modulates the crosstalk between the aryl hydrocarbon receptor and transforming growth factor-β1 signaling, enhancing human breast cancer cell migration and invasion.
Journal: Toxicology 20160729
Title: Arsenite and Cadmium Activate MAPK/ERK via Membrane Estrogen Receptors and G-Protein Coupled Estrogen Receptor Signaling in Human Lung Adenocarcinoma Cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160701
Title: Gallic acid abolishes the EGFR/Src/Akt/Erk-mediated expression of matrix metalloproteinase-9 in MCF-7 breast cancer cells.
Journal: Chemico-biological interactions 20160525
Title: EGFR participates downstream of ERα in estradiol-17β-D-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets.
Journal: Archives of toxicology 20160401
Title: Bisphenol A and Related Alkylphenols Exert Nongenomic Estrogenic Actions Through a G Protein-Coupled Estrogen Receptor 1 (Gper)/Epidermal Growth Factor Receptor (Egfr) Pathway to Inhibit Meiotic Maturation of Zebrafish Oocytes.
Journal: Biology of reproduction 20151201
Title: Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).
Journal: Archives of toxicology 20150801
Title: The anti-inflammatory effect of 2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol by targeting Lyn kinase in human neutrophils.
Journal: Chemico-biological interactions 20150705
Title: Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells.
Journal: The Journal of biological chemistry 20150619
Title: Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts.
Journal: Environmental health perspectives 20150501
Title: SRC-mediated EGF receptor activation regulates ozone-induced interleukin 8 expression in human bronchial epithelial cells.
Journal: Environmental health perspectives 20150301
Title: Lipopolysaccharide-induced caveolin-1 phosphorylation-dependent increase in transcellular permeability precedes the increase in paracellular permeability.
Journal: Drug design, development and therapy 20150101
Title: Src family kinase inhibitor PP2 enhances differentiation of acute promyelocytic leukemia cell line induced by combination of all-trans-retinoic acid and arsenic trioxide.
Journal: Leukemia research 20140801
Title: Reelin induces Erk1/2 signaling in cortical neurons through a non-canonical pathway.
Journal: The Journal of biological chemistry 20140718
Title: Areca nut components affect COX-2, cyclin B1/cdc25C and keratin expression, PGE2 production in keratinocyte is related to reactive oxygen species, CYP1A1, Src, EGFR and Ras signaling.
Journal: PloS one 20140101
Title: Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium.
Journal: Archives of toxicology 20131201
Title: Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells.
Journal: Immunobiology 20131201
Title: Inhibition of oxidized-phospholipid-induced vascular smooth muscle cell proliferation by resveratrol is associated with reducing Cx43 phosphorylation.
Journal: Journal of agricultural and food chemistry 20131106
Title: Indoxyl 3-sulfate stimulates Th17 differentiation enhancing phosphorylation of c-Src and STAT3 to worsen experimental autoimmune encephalomyelitis.
Journal: Toxicology letters 20130704
Title: Src Family Kinase Inhibitor PP2 Has Different Effects on All-Trans-Retinoic Acid or Arsenic Trioxide-Induced Differentiation of an Acute Promyelocytic Leukemia Cell Line.
Journal: Cancer research and treatment : official journal of Korean Cancer Association 20130601
Title: Action of hexachlorobenzene on tumor growth and metastasis in different experimental models.
Journal: Toxicology and applied pharmacology 20130501
Title: Bisphenol A at a low concentration boosts mouse spermatogonial cell proliferation by inducing the G protein-coupled receptor 30 expression.
Journal: Toxicology and applied pharmacology 20130215
Title: Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells.
Journal: Biochemical pharmacology 20130201
Title: Potent vasodilation effect of amurensin G is mediated through the phosphorylation of endothelial nitric oxide synthase.
Journal: Biochemical pharmacology 20121201
Title: O-Aryl α,β-d-ribofuranosides: synthesis & highly efficient biocatalytic separation of anomers and evaluation of their Src kinase inhibitory activity.
Journal: Bioorganic & medicinal chemistry 20121201
Title: Trogocytosis results in sustained intracellular signaling in CD4(+) T cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20121115
Title: Src modulates contractile vascular smooth muscle function via regulation of focal adhesions.
Journal: Journal of cellular physiology 20121101
Title: Ethanol disrupts axon outgrowth stimulated by netrin-1, GDNF, and L1 by blocking their convergent activation of Src family kinase signaling.
Journal: Journal of neurochemistry 20121101
Title: Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts.
Journal: Arthritis and rheumatism 20121001
Title: Activation of Src family kinases in spinal microglia contributes to formalin-induced persistent pain state through p38 pathway.
Journal: The journal of pain : official journal of the American Pain Society 20121001
Title: An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma.
Journal: Biochemical and biophysical research communications 20120928
Title: TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20120901
Title: GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes.
Journal: The Journal of biological chemistry 20120803
Title: The Src family kinase inhibitors PP2 and PP1 effectively block TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells.
Journal: Cancer chemotherapy and pharmacology 20120801
Title: PTPIP51 in protein interactions: regulation and in situ interacting partners.
Journal: Cell biochemistry and biophysics 20120701
Title: Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes.
Journal: Experimental cell research 20120610
Title: Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells.
Journal: Leukemia 20120601
Title: Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
Journal: Leukemia 20120601
Title: Testosterone induces vascular smooth muscle cell migration by NADPH oxidase and c-Src-dependent pathways.
Journal: Hypertension (Dallas, Tex. : 1979) 20120601
Title: Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells.
Journal: Cellular signalling 20120601
Title: Deficiency of Fyn protein is prerequisite for apoptosis induced by Src family kinase inhibitors in human mesothelioma cells.
Journal: Carcinogenesis 20120501
Title: Natriuretic effect of bufalin in isolated rat kidneys involves activation of the Na+-K+-ATPase-Src kinase pathway.
Journal: American journal of physiology. Renal physiology 20120415
Title: C-peptide induces human renal mesangial cell proliferation in vitro, activating Src-kinase, PI-3 kinase and ERK1/2.
Journal: Molecular and cellular endocrinology 20120404
Title: Apoptosis induced by SRC-family tyrosine kinase inhibitors in cultured rat cortical cells.
Journal: Neurotoxicity research 20120401
Title: The non-receptor tyrosine kinase c-Src mediates the PDGF-induced association between Furin and pro-MT1-MMP in HPAC pancreatic cells.
Journal: Molecular and cellular biochemistry 20120301
Title: Antitumor activity of new pyrazolo[3,4-d]pyrimidine SRC kinase inhibitors in Burkitt lymphoma cell lines and its enhancement by WEE1 inhibition.
Journal: Cell cycle (Georgetown, Tex.) 20120301
Title: Differential effects on cell motility, embryonic stem cell self-renewal and senescence by diverse Src kinase family inhibitors.
Journal: Experimental cell research 20120215
Title: Low concentrations of bisphenol a suppress thyroid hormone receptor transcription through a nongenomic mechanism.
Journal: Toxicology and applied pharmacology 20120215
Title: Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1 transcriptional activity.
Journal: Biochemical and biophysical research communications 20120203
Title: Progesterone enhances vascular endothelial cell migration via activation of focal adhesion kinase.
Journal: Journal of cellular and molecular medicine 20120201
Title: HMGB1 increases permeability of the endothelial cell monolayer via RAGE and Src family tyrosine kinase pathways.
Journal: Inflammation 20120201
Title: Cyclic stretch induces reorientation of cells in a Src family kinase- and p130Cas-dependent manner.
Journal: European journal of cell biology 20120201
Title: LPS induces phosphorylation of actin-regulatory proteins leading to actin reassembly and macrophage motility.
Journal: Journal of cellular biochemistry 20120101
Title: One-pot regioselective synthesis of tetrahydroindazolones and evaluation of their antiproliferative and Src kinase inhibitory activities.
Journal: Bioorganic & medicinal chemistry letters 20120101
Title: The tyrosine kinase c-Src directly mediates growth factor-induced Notch-1 and Furin interaction and Notch-1 activation in pancreatic cancer cells.
Journal: PloS one 20120101
Title: The role of Src kinase in the biology and pathogenesis of Acanthamoeba castellanii.
Journal: Parasites & vectors 20120101
Title: Palmitate contributes to insulin resistance through downregulation of the Src-mediated phosphorylation of Akt in C2C12 myotubes.
Journal: Bioscience, biotechnology, and biochemistry 20120101
Title: Effect of plasma membrane cholesterol depletion on glucose transport regulation in leukemia cells.
Journal: PloS one 20120101
Title: Down-regulation of phospho-non-receptor Src tyrosine kinases contributes to growth inhibition of cervical cancer cells.
Journal: Medical oncology (Northwood, London, England) 20111201
Title: VEGFR2 signalling contributes to increased endothelial susceptibility to TNF-α under chronic non-uniform shear stress.
Journal: Atherosclerosis 20111201
Title: Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2.
Journal: Cancer letters 20111128
Title: Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling.
Journal: The Journal of biological chemistry 20111111
Title: X-ray crystal structure of bone marrow kinase in the x chromosome: a Tec family kinase.
Journal: Chemical biology & drug design 20111101
Title: Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated.
Journal: American journal of surgery 20111101
Title: Depolarization induces NR2A tyrosine phosphorylation and neuronal apoptosis.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20111101
Title: Src regulates Tyr(20) phosphorylation of transferrin receptor-1 and potentiates breast cancer cell survival.
Journal: The Journal of biological chemistry 20111014
Title: Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells.
Journal: Free radical biology & medicine 20110915
Title: Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.
Journal: Cell cycle (Georgetown, Tex.) 20110915
Title: Human mast cell line-1 (HMC-1) cells transfected with FcεRIα are sensitive to IgE/antigen-mediated stimulation demonstrating selectivity towards cytokine production.
Journal: International immunopharmacology 20110801
Title: HMGB-1 induces IL-6 production in human synovial fibroblasts through c-Src, Akt and NF-κB pathways.
Journal: Journal of cellular physiology 20110801
Title: Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition.
Journal: Biochimica et biophysica acta 20110801
Title: Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death.
Journal: Cancer biology & therapy 20110801
Title: Signaling cascades mediate astrocyte death induced by zinc.
Journal: Toxicology letters 20110728
Title: Cyanidin-3-glucoside suppresses B[a]PDE-induced cyclooxygenase-2 expression by directly inhibiting Fyn kinase activity.
Journal: Biochemical pharmacology 20110715
Title: Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer.
Journal: The Journal of clinical investigation 20110701
Title: Formation of invadopodia-like structures by synovial cells promotes cartilage breakdown in collagen-induced arthritis: involvement of the protein tyrosine kinase Src.
Journal: Arthritis and rheumatism 20110601
Title: The potential of nanoscale combinations of self-assembling peptides and amino acids of the Src tyrosine kinase inhibitor in acute lung injury therapy.
Journal: Biomaterials 20110601
Title: The Src family kinase inhibitors PP2 and PP1 block TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors.
Journal: Current cancer drug targets 20110501
Title: 5-Hydroxytryptamine induces cyclooxygenase-2 in rat vascular smooth muscle cells: Mechanisms involving Src, PKC and MAPK activation [corrected].
Journal: European journal of pharmacology 20110410
Title: FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor.
Journal: Biochimica et biophysica acta 20110401
Title: Activation of c-Src/HER1/STAT5b and HER1/ERK1/2 signaling pathways and cell migration by hexachlorobenzene in MDA-MB-231 human breast cancer cell line.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401
Title: Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30.
Journal: Hypertension (Dallas, Tex. : 1979) 20110401
Title: c-Src in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats.
Journal: Pflugers Archiv : European journal of physiology 20110401
Title: Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities.
Journal: Bioorganic & medicinal chemistry letters 20110301
Title: A positive feedback loop of ER-α36/EGFR promotes malignant growth of ER-negative breast cancer cells.
Journal: Oncogene 20110217
Title: Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling.
Journal: The Journal of biological chemistry 20110211
Title: Lyn kinase regulates mesolimbic dopamine release: implication for alcohol reward.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209
Title: A novel pathway for receptor-mediated post-translational activation of inducible nitric oxide synthase.
Journal: Journal of cellular and molecular medicine 20110201
Title: Src kinase family inhibitor PP2 induces aggregation and detachment of neuroblastoma cells and inhibits cell growth in a PI3 kinase/Akt pathway-independent manner.
Journal: Pediatric surgery international 20110201
Title: Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173.
Journal: Molecular and cellular biochemistry 20110201
Title: EphrinB2 induces pelvic-urethra reflex potentiation via Src kinase-dependent tyrosine phosphorylation of NR2B.
Journal: American journal of physiology. Renal physiology 20110201
Title: Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells.
Journal: Immunobiology 20110101
Title: Click chemistry inspired one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their Src kinase inhibitory activity.
Journal: Bioorganic & medicinal chemistry letters 20110101
Title: Activation of Src-ATF1 pathway is involved in upregulation of Nox1, a catalytic subunit of NADPH oxidase, by aldosterone.
Journal: Endocrine journal 20110101
Title: The CCL5/CCR5 axis promotes interleukin-6 production in human synovial fibroblasts.
Journal: Arthritis and rheumatism 20101201
Title: Involvement of Src family tyrosine kinase in apoptosis of human neutrophils induced by protozoan parasite Entamoeba histolytica.
Journal: The Korean journal of parasitology 20101201
Title: Human remyelination promoting antibody inhibits apoptotic signaling and differentiation through Lyn kinase in primary rat oligodendrocytes.
Journal: Glia 20101115
Title: Gold nanoparticles downregulate VEGF-and IL-1β-induced cell proliferation through Src kinase in retinal pigment epithelial cells.
Journal: Experimental eye research 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: VEGF secretion during hypoxia depends on free radicals-induced Fyn kinase activity in mast cells.
Journal: Biochemical and biophysical research communications 20101015
Title: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen.
Journal: The Journal of biological chemistry 20100917
Title: mGluR1 antagonist decreased NADPH oxidase activity and superoxide production after transient focal cerebral ischemia.
Journal: Journal of neurochemistry 20100901
Title: Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1.
Journal: Cancer research 20100901
Title: Plumbagin activates ERK1/2 and Akt via superoxide, Src and PI3-kinase in 3T3-L1 cells.
Journal: European journal of pharmacology 20100725
Title: A role for Src kinase in progestin facilitation of estrous behavior in estradiol-primed female rats.
Journal: Hormones and behavior 20100701
Title: Deciphering mechanisms controlling placental artery endothelial cell migration stimulated by vascular endothelial growth factor.
Journal: Endocrinology 20100701
Title: Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase.
Journal: Bioorganic & medicinal chemistry 20100701
Title: Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.
Journal: Blood 20100610
Title: Constitutive nitric oxide synthase-mediated caspase-3 S-nitrosylation in ghrelin protection against Porphyromonas gingivalis-induced salivary gland acinar cell apoptosis.
Journal: Inflammopharmacology 20100601
Title: Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100601
Title: Src tyrosine kinase regulates angiotensin II-induced protein kinase Czeta activation and proliferation in vascular smooth muscle cells.
Journal: Peptides 20100601
Title: E-cadherin mediates the aggregation of breast cancer cells induced by tamoxifen and epidermal growth factor.
Journal: Breast cancer research and treatment 20100501
Title: Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1.
Journal: Molecular endocrinology (Baltimore, Md.) 20100501
Title: An important role of the SRC family kinase Lyn in stimulating platelet granule secretion.
Journal: The Journal of biological chemistry 20100423
Title: Comprehensive screening of human genes with inhibitory effects on yeast growth and validation of a yeast cell-based system for screening chemicals.
Journal: Journal of biomolecular screening 20100401
Title: Blood-brain barrier breakdown and repair by Src after thrombin-induced injury.
Journal: Annals of neurology 20100401
Title: Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria.
Journal: American journal of physiology. Cell physiology 20100301
Title: Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells.
Journal: The Journal of steroid biochemistry and molecular biology 20100227
Title: Dissecting the factors involved in the locomotion mode of neuronal migration in the developing cerebral cortex.
Journal: The Journal of biological chemistry 20100219
Title: Chromium(VI) stimulates Fyn to initiate innate immune gene induction in human airway epithelial cells.
Journal: Chemical research in toxicology 20100215
Title: TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys.
Journal: Biochemical pharmacology 20100201
Title: Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100127
Title: Diesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3.
Journal: American journal of respiratory cell and molecular biology 20100101
Title: Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1.
Journal: Experimental cell research 20100101
Title: Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation.
Journal: The Journal of biological chemistry 20100101
Title: Roles of Src family kinase signaling during fertilization and the first cell cycle in the marine protostome worm Cerebratulus.
Journal: The International journal of developmental biology 20100101
Title: Src kinases are required for a balanced production of IL-12/IL-23 in human dendritic cells activated by Toll-like receptor agonists.
Journal: PloS one 20100101
Title: Bacillus anthracis spore entry into epithelial cells is an actin-dependent process requiring c-Src and PI3K.
Journal: PloS one 20100101
Title: Density- and serum-dependent regulation of the Reck tumor suppressor in mouse embryo fibroblasts.
Journal: Cellular signalling 20091201
Title: Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cells.
Journal: Canadian journal of physiology and pharmacology 20091201
Title: Kinetic mechanism and inhibitor characterization of WNK1 kinase.
Journal: Biochemistry 20091103
Title: The interaction of estrogen receptor alpha and caveolin-3 regulates connexin43 phosphorylation in metabolic inhibition-treated rat cardiomyocytes.
Journal: The international journal of biochemistry & cell biology 20091101
Title: Oxytocin stimulates in vitro angiogenesis via a Pyk-2/Src-dependent mechanism.
Journal: Experimental cell research 20091101
Title: Hippocampal Fyn activity regulates extinction of contextual fear.
Journal: Neuroreport 20091028
Title: NADPH oxidase and lipid raft-associated redox signaling are required for PCB153-induced upregulation of cell adhesion molecules in human brain endothelial cells.
Journal: Toxicology and applied pharmacology 20091015
Title: Phosphate-affinity electrophoresis on a microchip for determination of protein kinase activity.
Journal: Electrophoresis 20091001
Title: Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2.
Journal: Journal of cell science 20090915
Title: Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling.
Journal: Oncogene 20090910
Title: CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.
Journal: European journal of immunology 20090901
Title: Fluoride-induced cyclooxygenase-2 expression and prostaglandin E2 production in A549 human pulmonary epithelial cells.
Journal: Toxicology letters 20090810
Title: Inhibition of imatinib-mediated apoptosis by the caspase-cleaved form of the tyrosine kinase Lyn in chronic myelogenous leukemia cells.
Journal: Leukemia 20090801
Title: Activation of the lutropin/choriogonadotropin receptor inhibits apoptosis of immature Leydig cells in primary culture.
Journal: Endocrinology 20090801
Title: Prolactin induces chitotriosidase expression in human macrophages through PTK, PI3-K, and MAPK pathways.
Journal: Journal of cellular biochemistry 20090801
Title: Fibroblast growth factor-2 autofeedback regulation in pituitary folliculostellate TtT/GF cells.
Journal: Endocrinology 20090701
Title: Signal transducer and activator of transcription 1 (STAT1) is essential for chromium silencing of gene induction in human airway epithelial cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090701
Title: Inhibition of Src activity decreases tyrosine phosphorylation of occludin in brain capillaries and attenuates increase in permeability of the blood-brain barrier after transient focal cerebral ischemia.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090601
Title: Reciprocal regulation of 17beta-estradiol, interleukin-6 and interleukin-8 during growth and progression of epithelial ovarian cancer.
Journal: Cytokine 20090601
Title: Overexpression of human histone methylase MLL1 upon exposure to a food contaminant mycotoxin, deoxynivalenol.
Journal: The FEBS journal 20090601
Title: Src supports UDP-glucuronosyltransferase-2B7 detoxification of catechol estrogens associated with breast cancer.
Journal: Biochemical and biophysical research communications 20090515
Title: Discovering novel quercetin-3-O-amino acid-esters as a new class of Src tyrosine kinase inhibitors.
Journal: European journal of medicinal chemistry 20090501
Title: Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.
Journal: Cell research 20090501
Title: The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20090401
Title: Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-alpha.
Journal: Biochemical pharmacology 20090401
Title: Rapamycin induces transactivation of the EGFR and increases cell survival.
Journal: Oncogene 20090305
Title: A potential role for caveolin-1 in estradiol-17beta-induced proliferation of mouse embryonic stem cells: involvement of Src, PI3K/Akt, and MAPKs pathways.
Journal: The international journal of biochemistry & cell biology 20090301
Title: HD-PTP inhibits endothelial migration through its interaction with Src.
Journal: The international journal of biochemistry & cell biology 20090301
Title: Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090301
Title: Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages.
Journal: Chemosphere 20090301
Title: Temporal perturbation of tyrosine phosphoproteome dynamics reveals the system-wide regulatory networks.
Journal: Molecular & cellular proteomics : MCP 20090201
Title: Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression.
Journal: Carcinogenesis 20090201
Title: Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state.
Journal: The Journal of biological chemistry 20090102
Title: Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling.
Journal: Journal of cellular and molecular medicine 20090101
Title: FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction.
Journal: Investigative ophthalmology & visual science 20090101
Title: Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines.
Journal: International journal of cancer 20090101
Title: Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
Journal: Experimental & molecular medicine 20081231
Title: Reduced expression of SRC family kinases decreases PI3K activity in NBS1-/- lymphoblasts.
Journal: Biochemical and biophysical research communications 20081205
Title: Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling.
Journal: Oncogene 20081204
Title: Genistein combined polysaccharide enhances activity of docetaxel, bicalutamide and Src kinase inhibition in androgen-dependent and independent prostate cancer cell lines.
Journal: BJU international 20081101
Title: The Src tyrosine kinase pathway regulates thecal CYP17 expression and androstenedione secretion.
Journal: Molecular and cellular biochemistry 20081101
Title: Testosterone potentially triggers meiotic resumption by activation of intra-oocyte SRC and MAPK in porcine oocytes.
Journal: Biology of reproduction 20081101
Title: Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways.
Journal: Circulation research 20081010
Title: Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals.
Journal: Carcinogenesis 20081001
Title: Both EGFR kinase and Src-related tyrosine kinases regulate human ether-à-go-go-related gene potassium channels.
Journal: Cellular signalling 20081001
Title: PP2 regulates human trophoblast cells differentiation by activating p38 and ERK1/2 and inhibiting FAK activation.
Journal: Placenta 20081001
Title: Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis.
Journal: The Journal of biological chemistry 20080926
Title: Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20080923
Title: Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells.
Journal: Molecular cancer therapeutics 20080901
Title: Lysophosphatidic acid induces ovarian cancer cell dispersal by activating Fyn kinase associated with p120-catenin.
Journal: International journal of cancer 20080815
Title: Inhibition of NR2B phosphorylation restores alterations in NMDA receptor expression and improves functional recovery following traumatic brain injury in mice.
Journal: Journal of neurotrauma 20080801
Title: Type 1 TNF receptor forms a complex with and uses Jak2 and c-Src to selectively engage signaling pathways that regulate transcription factor activity.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080715
Title: Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells.
Journal: Molecular pharmacology 20080701
Title: Src-family protein tyrosine kinase negatively regulates cerebellar long-term depression.
Journal: Neuroscience research 20080701
Title: CD98 activation increases surface expression and clusteringof beta1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms.
Journal: Experimental & molecular medicine 20080630
Title: Tyrosine phosphorylation of HPK1 by activated Src promotes ischemic brain injury in rat hippocampal CA1 region.
Journal: FEBS letters 20080611
Title: Role of Src-family kinases in formation of the cortical actin cap at the dorsal cell surface.
Journal: Experimental cell research 20080610
Title: Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes.
Journal: Pflugers Archiv : European journal of physiology 20080601
Title: House dust mite, Dermatophagoides pteronissinus increases expression of MCP-1, IL-6, and IL-8 in human monocytic THP-1 cells.
Journal: Cytokine 20080601
Title: The small peptide OGP(10-14) acts through Src kinases and RhoA pathways in Mo-7e cells: morphologic and immunologic evaluation.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20080601
Title: Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death.
Journal: Biochemical and biophysical research communications 20080530
Title: The role of RIP2 in p38 MAPK activation in the stressed heart.
Journal: The Journal of biological chemistry 20080502
Title: Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501
Title: Molecular requirements for induction of CTGF expression by TGF-beta1 in primary osteoblasts.
Journal: Bone 20080501
Title: Activated Src kinases interact with the N-methyl-D-aspartate receptor after neonatal brain ischemia.
Journal: Annals of neurology 20080501
Title: Tyrosine phosphorylation controls nuclear localization and transcriptional activity of Ssdp1 in mammalian cells.
Journal: Journal of cellular biochemistry 20080415
Title: Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401
Title: The early growth response factor-1 contributes to interleukin-13 production by mast cells in response to stem cell factor stimulation.
Journal: Journal of immunotoxicology 20080401
Title: Hexachlorobenzene triggers AhR translocation to the nucleus, c-Src activation and EGFR transactivation in rat liver.
Journal: Toxicology letters 20080315
Title: Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway.
Journal: Journal of neurochemistry 20080301
Title: Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.
Journal: American journal of physiology. Cell physiology 20080301
Title: Inhibition of Src reduces gemcitabine-induced cytotoxicity in human pancreatic cancer cell lines.
Journal: Cancer letters 20080218
Title: EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy.
Journal: Oncogene 20080207
Title: Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages.
Journal: Molecular immunology 20080201
Title: Thrombin increases hyposmotic taurine efflux and accelerates ICI-swell and RVD in 3T3 fibroblasts by a src-dependent EGFR transactivation.
Journal: Pflugers Archiv : European journal of physiology 20080201
Title: Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway.
Journal: Traffic (Copenhagen, Denmark) 20080201
Title: The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.
Journal: American journal of physiology. Renal physiology 20080201
Title: [Na+]i/[K+]i -independent death of ouabain-treated renal epithelial cells is not mediated by Na+,K+ -ATPase internalization and de novo gene expression.
Journal: Pflugers Archiv : European journal of physiology 20080101
Title: Src tyrosine kinase alters gating of hyperpolarization-activated HCN4 pacemaker channel through Tyr531.
Journal: American journal of physiology. Cell physiology 20080101
Title: Phosphorylation of caveolin-1 in bovine rod outer segments in vitro by an endogenous tyrosine kinase.
Journal: Advances in experimental medicine and biology 20080101
Title: Roles of c-Src in alpha1B-adrenoceptor phosphorylation and desensitization.
Journal: Autonomic & autacoid pharmacology 20080101
Title: Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.
Journal: The international journal of biochemistry & cell biology 20080101
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: EGFR plays a pivotal role in the regulation of polyamine-dependent apoptosis in intestinal epithelial cells.
Journal: Cellular signalling 20071201
Title: Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI.
Journal: Thrombosis and haemostasis 20071201
Title: Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.
Journal: The Journal of biological chemistry 20071130
Title: Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice.
Journal: Journal of medicinal chemistry 20071115
Title: Src and Pyk2 mediate angiotensin II effects in cultured rat astrocytes.
Journal: Regulatory peptides 20071004
Title: Activation of T cells by cross-linking Qa-2, the ped gene product, requires Fyn.
Journal: American journal of reproductive immunology (New York, N.Y. : 1989) 20071001
Title: Targeting c-Src kinase enhances tamoxifen's inhibitory effect on cell growth by modulating expression of cell cycle and survival proteins.
Journal: Cancer chemotherapy and pharmacology 20070901
Title: Label-free electrical sensing of small-molecule inhibition on tyrosine phosphorylation.
Journal: Analytical chemistry 20070901
Title: p38 mitogen-activated protein kinase contributes to angiotensin II-stimulated migration of rat aortic smooth muscle cells.
Journal: Journal of pharmacological sciences 20070901
Title: Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages.
Journal: Experimental & molecular medicine 20070831
Title: An ultrasensitive high-throughput electrochemiluminescence immunoassay for the Cdc42-associated protein tyrosine kinase ACK1.
Journal: Analytical biochemistry 20070815
Title: Purinergic agonists stimulate lens Na-K-ATPase-mediated transport via a Src tyrosine kinase-dependent pathway.
Journal: American journal of physiology. Cell physiology 20070801
Title: Effects of Rho-kinase and Src protein tyrosine kinase inhibition on agonist-induced vasoconstriction of arteries and veins of the equine laminar dermis.
Journal: American journal of veterinary research 20070801
Title: Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death.
Journal: Cancer research 20070801
Title: Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol.
Journal: The Journal of biological chemistry 20070706
Title: Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.
Journal: Endocrinology 20070701
Title: Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src-, TLR4-, and LBP-dependent mechanism.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701
Title: PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia.
Journal: Neuroscience letters 20070615
Title: Paxillin phosphorylation: bifurcation point downstream of integrin-linked kinase (ILK) in streptococcal invasion.
Journal: Cellular microbiology 20070601
Title: c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function.
Journal: Oncogene 20070524
Title: ERK-dependent and -independent pathways trigger human neural progenitor cell migration.
Journal: Toxicology and applied pharmacology 20070515
Title: Src and focal adhesion kinase mediate mechanical strain-induced proliferation and ERK1/2 phosphorylation in human H441 pulmonary epithelial cells.
Journal: American journal of physiology. Cell physiology 20070501
Title: Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration.
Journal: American journal of physiology. Cell physiology 20070501
Title: Anaplasma phagocytophilum AnkA is tyrosine-phosphorylated at EPIYA motifs and recruits SHP-1 during early infection.
Journal: Cellular microbiology 20070501
Title: Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1.
Journal: American journal of physiology. Cell physiology 20070501
Title: Testosterone activates mitogen-activated protein kinase via Src kinase and the epidermal growth factor receptor in sertoli cells.
Journal: Endocrinology 20070501
Title: Preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress.
Journal: The Journal of biological chemistry 20070406
Title: Vascular endothelial growth factor receptor-3 activity is modulated by its association with caveolin-1 on endothelial membrane.
Journal: Biochemistry 20070403
Title: The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070315
Title: Inhibitory role of Src family tyrosine kinases on Ca2+-dependent insulin release.
Journal: American journal of physiology. Endocrinology and metabolism 20070301
Title: Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD.
Journal: Leukemia 20070301
Title: Src family kinase activity regulates adhesion, spreading and migration of pancreatic endocrine tumour cells.
Journal: Endocrine-related cancer 20070301
Title: Diesel exhaust particulate-induced activation of Stat3 requires activities of EGFR and Src in airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070201
Title: Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070201
Title: GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20070201
Title: Ouabain triggers preconditioning through activation of the Na+,K+-ATPase signaling cascade in rat hearts.
Journal: Cardiovascular research 20070201
Title: Focal adhesion signaling is required for myometrial ERK activation and contractile phenotype switch before labor.
Journal: Journal of cellular biochemistry 20070101
Title: Interleukin 1-beta (IL-1beta) enhances contractile responses in endothelium-denuded aorta from hypertensive, but not normotensive, rats.
Journal: Vascular pharmacology 20070101
Title: SRC inhibitors and angiogenesis.
Journal: Current pharmaceutical design 20070101
Title: Activation of H2O2-induced VSOR Cl- currents in HTC cells require phospholipase Cgamma1 phosphorylation and Ca2+ mobilisation.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Title: P-selectin cross-links PSGL-1 and enhances neutrophil adhesion to fibrinogen and ICAM-1 in a Src kinase-dependent, but GPCR-independent mechanism.
Journal: Cell adhesion & migration 20070101
Title: Metabolic and signaling events mediated by cardiotonic steroid ouabain in rat skeletal muscle.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20061230
Title: PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]: evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets.
Journal: Journal of thrombosis and haemostasis : JTH 20061201
Title: 2,3,7,8-tetrachlorodibenzo-p-dioxin and epidermal growth factor cooperatively suppress peroxisome proliferator-activated receptor-gamma1 stimulation and restore focal adhesion complexes during adipogenesis: selective contributions of Src, Rho, and Erk distinguish these overlapping processes in C3H10T1/2 cells.
Journal: Molecular pharmacology 20061201
Title: Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones.
Journal: Molecular pharmacology 20061201
Title: Sustained activation of Src-family tyrosine kinases by ischemia: a potential mechanism mediating extracellular signal-regulated kinase cascades in hippocampal dentate gyrus.
Journal: Neuroscience 20061201
Title: Transmigration: a new property of mature multinucleated osteoclasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20061201
Title: Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.
Journal: Biochemical and biophysical research communications 20061117
Title: Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets.
Journal: The Biochemical journal 20061115
Title: LAR protein tyrosine phosphatase receptor associates with TrkB and modulates neurotrophic signaling pathways.
Journal: Journal of neurobiology 20061101
Title: Endothelial cell cortactin coordinates intercellular adhesion molecule-1 clustering and actin cytoskeleton remodeling during polymorphonuclear leukocyte adhesion and transmigration.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20061101
Title: Retinol induces the ERK1/2-dependent phosphorylation of CREB through a pathway involving the generation of reactive oxygen species in cultured Sertoli cells.
Journal: Cellular signalling 20061001
Title: Critical roles of Src family tyrosine kinases in excitatory neuronal differentiation of cultured embryonic stem cells.
Journal: Experimental cell research 20061001
Title: Regulation of androgen receptor activity by tyrosine phosphorylation.
Journal: Cancer cell 20061001
Title: Hydrogen peroxide-induced arachidonic acid release in L929 cells; roles of Src, protein kinase C and cytosolic phospholipase A2alpha.
Journal: European journal of pharmacology 20060928
Title: The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells.
Journal: The Journal of biological chemistry 20060915
Title: Src family kinases regulate p38 MAPK-mediated IL-6 production in Kupffer cells following hypoxia.
Journal: American journal of physiology. Cell physiology 20060901
Title: Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone-stimulated increases in cytosolic free Ca2+ and insulin secretion.
Journal: American journal of physiology. Cell physiology 20060901
Title: Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy.
Journal: Laboratory investigation; a journal of technical methods and pathology 20060901
Title: Serotonin stimulates GnRH secretion through the c-Src-PLC gamma1 pathway in GT1-7 hypothalamic cells.
Journal: The Journal of endocrinology 20060901
Title: P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1.
Journal: Cellular signalling 20060801
Title: Integrin beta3-mediated Src activation regulates apoptosis in IEC-6 cells via Akt and STAT3.
Journal: The Biochemical journal 20060801
Title: Role of a tyrosine kinase in the CO2-induced stimulation of HCO3- reabsorption by rabbit S2 proximal tubules.
Journal: American journal of physiology. Renal physiology 20060801
Title: SRC-family tyrosine kinases in wound- and ligand-induced epidermal growth factor receptor activation in human corneal epithelial cells.
Journal: Investigative ophthalmology & visual science 20060701
Title: Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells.
Journal: Canadian journal of physiology and pharmacology 20060701
Title: Serotonin acts as an up-regulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages.
Journal: Atherosclerosis 20060601
Title: Regulation of Ly49D/DAP12 signal transduction by Src-family kinases and CD45.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060601
Title: Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction.
Journal: FEBS letters 20060529
Title: Increased Src kinase level results in increased protein tyrosine phosphorylation in scrapie-infected neuronal cell lines.
Journal: FEBS letters 20060515
Title: Arachidonic acid induces ERK activation via Src SH2 domain association with the epidermal growth factor receptor.
Journal: Kidney international 20060501
Title: The molecular mechanism of EGF receptor activation in pancreatic beta-cells by thyrotropin-releasing hormone.
Journal: American journal of physiology. Endocrinology and metabolism 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Regulation of protein kinase C delta by phorbol ester, endothelin-1, and platelet-derived growth factor in cardiac myocytes.
Journal: The Journal of biological chemistry 20060331
Title: Src-dependent aprotein kinase C iota/lambda (aPKCiota/lambda) tyrosine phosphorylation is required for aPKCiota/lambda association with Rab2 and glyceraldehyde-3-phosphate dehydrogenase on pre-golgi intermediates.
Journal: The Journal of biological chemistry 20060331
Title: Src family kinases play multiple roles in differentiation of trophoblasts from human term placenta.
Journal: The Journal of physiology 20060315
Title: Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
Title: Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation.
Journal: Biochemical and biophysical research communications 20060310
Title: Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.
Journal: Journal of medicinal chemistry 20060309
Title: MAP kinases p38 and JNK are activated by the steroid hormone 1alpha,25(OH)2-vitamin D3 in the C2C12 muscle cell line.
Journal: Journal of cellular biochemistry 20060301
Title: Activation of the lutropin/choriogonadotropin receptor in MA-10 cells leads to the tyrosine phosphorylation of the focal adhesion kinase by a pathway that involves Src family kinases.
Journal: Molecular endocrinology (Baltimore, Md.) 20060301
Title: Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferation.
Journal: Endocrinology 20060301
Title: P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activation.
Journal: Journal of thrombosis and haemostasis : JTH 20060301
Title: Nonsteroidal anti-inflammatory drugs inhibit the growth of C6 and U138-MG glioma cell lines.
Journal: European journal of pharmacology 20060227
Title: Role of Src family kinase in the rewarding effect and hyperlocomotion induced by morphine.
Journal: Neuroreport 20060206
Title: Lipopolysaccharide-induced c-Src expression plays a role in nitric oxide and TNFalpha secretion in macrophages.
Journal: Molecular immunology 20060201
Title: Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060201
Title: Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways.
Journal: Journal of cellular biochemistry 20060201
Title: Identification of tyrosine residues crucial for CD200R-mediated inhibition of mast cell activation.
Journal: Journal of leukocyte biology 20060201
Title: B cell proliferation following CD40 stimulation results in the expression and activation of Src protein tyrosine kinase.
Journal: International immunology 20060201
Title: Abl collaborates with Src family kinases to stimulate actin-based motility of vaccinia virus.
Journal: Cellular microbiology 20060201
Title: Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.
Journal: Toxicology 20060116
Title: A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.
Journal: Blood 20060115
Title: Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport?
Journal: American journal of physiology. Endocrinology and metabolism 20060101
Title: Analyzing the mechanism of Rap1 activation in platelets: Rap1 activation is related to the release reaction mediated through the collagen receptor GPVI.
Journal: Thrombosis research 20060101
Title: Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
Journal: Chemical biology & drug design 20060101
Title: Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis.
Journal: Arthritis research & therapy 20060101
Title: Focal adhesion kinase is involved in type III group B streptococcal invasion of human brain microvascular endothelial cells.
Journal: Microbial pathogenesis 20060101
Title: Expression of human tyrosine kinase, Lck, in yeast Saccharomyces cerevisiae: growth suppression and strategy for inhibitor screening.
Journal: Protein and peptide letters 20060101
Title: Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases.
Journal: Biochimica et biophysica acta 20051230
Title: NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.
Journal: The EMBO journal 20051221
Title: Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells.
Journal: The Journal of biological chemistry 20051202
Title: Re-distribution of phospholipase C gamma 2 in macrophage precursors is mediated by the actin cytoskeleton under the control of the Src kinases.
Journal: Cellular signalling 20051201
Title: Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta.
Journal: Cancer chemotherapy and pharmacology 20051201
Title: Kit-activating mutations cooperate with Spi-1/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice.
Journal: Cancer cell 20051201
Title: Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity.
Journal: The European journal of neuroscience 20051201
Title: PP2 inhibits glutamate release from nerve endings by affecting vesicle mobilization.
Journal: Neuroreport 20051128
Title: Phosphorylation of ephrin-B1 via the interaction with claudin following cell-cell contact formation.
Journal: The EMBO journal 20051102
Title: p38 and EGF receptor kinase-mediated activation of the phosphatidylinositol 3-kinase/Akt pathway is required for Zn2+-induced cyclooxygenase-2 expression.
Journal: American journal of physiology. Lung cellular and molecular physiology 20051101
Title: Experimental treatment for focal hyperglycemic ischemic brain injury in the rat.
Journal: Experimental brain research 20051101
Title: Src kinase activates endothelial nitric-oxide synthase by phosphorylating Tyr-83.
Journal: The Journal of biological chemistry 20051028
Title: Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.
Journal: European journal of pharmacology 20051003
Title: Beta-arrestin2 enhances beta2-adrenergic receptor-mediated nuclear translocation of ERK.
Journal: Cellular signalling 20051001
Title: Air pollution particles activate NF-kappaB on contact with airway epithelial cell surfaces.
Journal: Toxicology and applied pharmacology 20051001
Title: Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells.
Journal: Cardiovascular research 20050901
Title: Aldosterone induces angiotensin converting enzyme gene expression via a JAK2-dependent pathway in rat endothelial cells.
Journal: Endocrinology 20050901
Title: Peptidoglycan of Staphylococcus aureus induces enhanced levels of matrix metalloproteinase-9 in human blood originating from neutrophils.
Journal: Shock (Augusta, Ga.) 20050901
Title: Regulation of matrix metalloproteinase-9 release from IL-8-stimulated human neutrophils.
Journal: Journal of leukocyte biology 20050701
Title: Prostaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblasts.
Journal: The Journal of biological chemistry 20050617
Title: Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050615
Title: Integrin activation and neurotrophin signaling cooperate to enhance neurite outgrowth in sensory neurons.
Journal: The Journal of comparative neurology 20050606
Title: Antagonistic regulation of swelling-activated Cl- current in rabbit ventricle by Src and EGFR protein tyrosine kinases.
Journal: American journal of physiology. Heart and circulatory physiology 20050601
Title: Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050601
Title: Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.
Journal: Investigative ophthalmology & visual science 20050601
Title: Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells.
Journal: The Journal of endocrinology 20050601
Title: Src-mediated tyrosine phosphorylation of p47phox in hyperoxia-induced activation of NADPH oxidase and generation of reactive oxygen species in lung endothelial cells.
Journal: The Journal of biological chemistry 20050527
Title: alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells.
Journal: Experimental cell research 20050515
Title: Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 2. Identification of small-molecule inhibitors via coupling with virtual screening.
Journal: Journal of medicinal chemistry 20050505
Title: Integrin signaling cascades are operational in adult hippocampal synapses and modulate NMDA receptor physiology.
Journal: Journal of neurochemistry 20050501
Title: Extinction and reacquisition of a fear-motivated memory require activity of the Src family of tyrosine kinases in the CA1 region of the hippocampus.
Journal: Pharmacology, biochemistry, and behavior 20050501
Title: HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.
Journal: Oncogene 20050428
Title: Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells.
Journal: The Journal of biological chemistry 20050401
Title: Residues within the first subdomain of the FERM-like domain in focal adhesion kinase are important in its regulation.
Journal: The Journal of biological chemistry 20050304
Title: Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells.
Journal: The Journal of biological chemistry 20050304
Title: Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts.
Journal: The Journal of pharmacology and experimental therapeutics 20050301
Title: Pigment epithelium-derived factor inhibits fibroblast-growth-factor-2-induced capillary morphogenesis of endothelial cells through Fyn.
Journal: Journal of cell science 20050301
Title: Cross-linking of 4-1BB activates TCR-signaling pathways in CD8+ T lymphocytes.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050215
Title: c-Src is involved in regulating signal transmission from PDGFbeta receptor-GPCR(s) complexes in mammalian cells.
Journal: Cellular signalling 20050201
Title: Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.
Journal: The Journal of clinical investigation 20050201
Title: Position of Src tyrosine kinases in the interaction between angiotensin II and endothelin in in vivo vascular protein synthesis.
Journal: Journal of hypertension 20050201
Title: Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9-independent activation of caspase-3.
Journal: Molecular cancer therapeutics 20050201
Title: Functional role of c-Src in IL-1-induced NF-kappa B activation: c-Src is a component of the IKK complex.
Journal: Journal of biochemistry 20050201
Title: Brevetoxin augments NMDA receptor signaling in murine neocortical neurons.
Journal: Brain research 20050107
Title: Modulation of cell adhesion molecules in various epithelial cell lines after treatment with PP2.
Journal: Molecular pharmaceutics 20050101
Title: Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation.
Journal: The Journal of biological chemistry 20041217
Title: Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2.
Journal: The Journal of biological chemistry 20041119
Title: Src tyrosine kinase regulates insulin-induced activation of protein kinase C (PKC) delta in skeletal muscle.
Journal: Cellular signalling 20041101
Title: Activation of FAK and Src are receptor-proximal events required for netrin signaling.
Journal: Nature neuroscience 20041101
Title: Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.
Journal: The Journal of biological chemistry 20041029
Title: Transforming growth factor-beta1-dependent activation of Smad2/3 and up-regulation of PAI-1 expression is negatively regulated by Src in SKOV-3 human ovarian cancer cells.
Journal: Journal of cellular biochemistry 20041015
Title: Apoptotic effect of PP2 a Src tyrosine kinase inhibitor, in murine B cell leukemia.
Journal: Journal of cellular biochemistry 20041015
Title: Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 1. Comparison with conventional ELISA.
Journal: Journal of medicinal chemistry 20041007
Title: Okadaic acid induces apoptosis through double-stranded RNA-dependent protein kinase/eukaryotic initiation factor-2alpha pathway in human osteoblastic MG63 cells.
Journal: Journal of biochemistry 20041001
Title: Porphyromonas gingivalis lipopolysaccharide-induced up-regulation in endothelin-1 interferes with salivary mucin synthesis via epidermal growth factor receptor transactivation.
Journal: IUBMB life 20041001
Title: Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040922
Title: Src family kinase-inhibitor PP2 reduces focal ischemic brain injury.
Journal: Acta neurologica Scandinavica 20040901
Title: Secretion of gastric mucus phospholipids in response to beta-adrenergic G protein-coupled receptor activation is mediated by SRC kinase-dependent epidermal growth factor receptor transactivation.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901
Title: The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity.
Journal: The Biochemical journal 20040815
Title: A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2.
Journal: The Journal of biological chemistry 20040813
Title: Functional re-establishment of the perforant pathway in organotypic co-cultures on microelectrode arrays.
Journal: Brain research 20040813
Title: Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors.
Journal: Oncogene 20040812
Title: Recruitment of the cross-linked opsonic receptor CD32A (FcgammaRIIA) to high-density detergent-resistant membrane domains in human neutrophils.
Journal: The Biochemical journal 20040801
Title: Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment.
Journal: Hypertension (Dallas, Tex. : 1979) 20040801
Title: The role of the Src family of tyrosine kinases after oxidant-induced lung injury in vivo.
Journal: Surgery 20040801
Title: Extracellular oxidation by taurine chloramine activates ERK via the epidermal growth factor receptor.
Journal: The Journal of biological chemistry 20040730
Title: NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation.
Journal: Blood 20040701
Title: Interactions between NMDA receptors and mGlu5 receptors expressed in HEK293 cells.
Journal: British journal of pharmacology 20040701
Title: Manganese-induced integrin affinity maturation promotes recruitment of alpha V beta 3 integrin to focal adhesions in endothelial cells: evidence for a role of phosphatidylinositol 3-kinase and Src.
Journal: Thrombosis and haemostasis 20040701
Title: Antiproliferative effects of Src inhibition on medullary thyroid cancer.
Journal: The Journal of clinical endocrinology and metabolism 20040701
Title: The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.
Journal: The Journal of biological chemistry 20040625
Title: Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress.
Journal: The Journal of biological chemistry 20040625
Title: Salivary phospholipid secretion in response to beta-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation.
Journal: Biochemical and biophysical research communications 20040521
Title: Carbachol regulation of rabbit ileal brush border Na+-H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent.
Journal: The Journal of physiology 20040501
Title: CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras.
Journal: Biochemical pharmacology 20040415
Title: Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.
Journal: Circulation research 20040402
Title: Collagen IV regulates Caco-2 migration and ERK activation via alpha1beta1- and alpha2beta1-integrin-dependent Src kinase activation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040401
Title: A critical 'threshold' of beta 2-integrin engagement regulates augmentation of cytokine-mediated superoxide anion release.
Journal: British journal of pharmacology 20040401
Title: Evidence that activation of Src family kinase is not required for fertilization-associated [Ca2+]i oscillations in mouse eggs.
Journal: Reproduction (Cambridge, England) 20040401
Title: Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040401
Title: Caspase-3: its potential involvement in Cr(III)-induced apoptosis of lymphocytes.
Journal: Molecular and cellular biochemistry 20040401
Title: Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src.
Journal: Circulation research 20040319
Title: Distinct regulation of internalization and mitogen-activated protein kinase activation by two isoforms of the dopamine D2 receptor.
Journal: Molecular endocrinology (Baltimore, Md.) 20040301
Title: Activation of Syk in neutrophils by antineutrophil cytoplasm antibodies occurs via Fcgamma receptors and CD18.
Journal: Journal of the American Society of Nephrology : JASN 20040301
Title: Matrix-specific activation of Src and Rho initiates capillary morphogenesis of endothelial cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040301
Title: Quantitative measurement of estrogen-induced ERK 1 and 2 activation via multiple membrane-initiated signaling pathways.
Journal: Steroids 20040301
Title: Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors.
Journal: The Journal of biological chemistry 20040227
Title: Combination of an SRC kinase inhibitor with a novel pharmacological antagonist of the urokinase receptor diminishes in vitro colon cancer invasiveness.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040215
Title: Pervanadate-induced reverse translocation and tyrosine phosphorylation of phorbol ester-stimulated protein kinase C betaII are mediated by Src-family tyrosine kinases in porcine neutrophils.
Journal: Biochemical and biophysical research communications 20040213
Title: Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos.
Journal: Oncogene 20040122
Title: EphB4 signaling is capable of mediating ephrinB2-induced inhibition of cell migration.
Journal: Biochemical and biophysical research communications 20040102
Title: Pyrazolo pyrimidine-type inhibitors of SRC family tyrosine kinases promote ovarian steroid-induced differentiation of human endometrial stromal cells in vitro.
Journal: Biology of reproduction 20040101
Title: Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway.
Journal: The Journal of pharmacology and experimental therapeutics 20040101
Title: Superantigen stimulation reveals the contribution of Lck to negative regulation of T cell activation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040101
Title: Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling.
Journal: Gastroenterology 20040101
Title: Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031201
Title: Apoptosis of lymphocytes induced by chromium(VI/V) is through ROS-mediated activation of Src-family kinases and caspase-3.
Journal: Free radical biology & medicine 20031101
Title: Platelet adhesion to collagen and collagen-related peptide under flow: roles of the [alpha]2[beta]1 integrin, GPVI, and Src tyrosine kinases.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20031001
Title: Beta1 integrins are distributed in adhesion structures with fibronectin and caveolin and in coated pits.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20031001
Title: c-Src kinase activation regulates preprotachykinin gene expression and substance P secretion in rat sensory ganglia.
Journal: The European journal of neuroscience 20031001
Title: Role of Src in hypersensitization to phosphodiesterase inhibitors in beta2-adrenoceptor-desensitized eosinophils.
Journal: Methods and findings in experimental and clinical pharmacology 20030901
Title: Src kinase mediates the regulation of phospholipase C-gamma activity by glycosphingolipids.
Journal: The Journal of biological chemistry 20030815
Title: Mechanisms of Zn(2+)-induced signal initiation through the epidermal growth factor receptor.
Journal: Toxicology and applied pharmacology 20030815
Title: Regulation of TGF-alpha-induced activation of AP-1 in the aging gastric mucosa.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20030801
Title: Evidence for ERK1/2 activation by thrombin that is independent of EGFR transactivation.
Journal: American journal of physiology. Heart and circulatory physiology 20030801
Title: Aberrant Connexin 43 endocytosis by the carcinogen lindane involves activation of the ERK/mitogen-activated protein kinase pathway.
Journal: Carcinogenesis 20030801
Title: Contribution of Src tyrosine kinase to cerebral vasospasm after subarachnoid hemorrhage.
Journal: Journal of neurosurgery 20030801
Title: Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.
Journal: Molecular cancer research : MCR 20030801
Title: Oxidant-induced priming of the macrophage involves activation of p38 mitogen-activated protein kinase through an Src-dependent pathway.
Journal: Surgery 20030801
Title: Inhibition of fast sodium current in rabbit ventricular myocytes by protein tyrosine kinase inhibitors.
Journal: Pflugers Archiv : European journal of physiology 20030701
Title: Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity.
Journal: The Biochemical journal 20030615
Title: Ephrin-A1 induces c-Cbl phosphorylation and EphA receptor down-regulation in T cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615
Title: Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615
Title: c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030601
Title: Expression, purification, and biochemical characterization of Chk, a soluble protein tyrosine kinase.
Journal: Protein expression and purification 20030601
Title: Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030501
Title: PP1 inhibitor induces degradation of RETMEN2A and RETMEN2B oncoproteins through proteosomal targeting.
Journal: Cancer research 20030501
Title: Inhibitors that target protein kinases for the treatment of ovarian carcinoma.
Journal: American journal of obstetrics and gynecology 20030501
Title: Down-regulation of cell surface CXCR6 expression during T cell activation is predominantly mediated by calcineurin.
Journal: Cellular immunology 20030501
Title: Protein tyrosine kinase signaling is necessary for NO donor-induced late preconditioning against myocardial stunning.
Journal: American journal of physiology. Heart and circulatory physiology 20030401
Title: The specificities of protein kinase inhibitors: an update.
Journal: The Biochemical journal 20030401
Title: IGF-I induces vascular endothelial growth factor in human mesangial cells via a Src-dependent mechanism.
Journal: Kidney international 20030401
Title: Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).
Journal: The Journal of clinical endocrinology and metabolism 20030401
Title: Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria-transformed B lymphocytes.
Journal: Blood 20030301
Title: Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens.
Journal: American journal of physiology. Renal physiology 20030301
Title: Toll-like receptor-mediated tyrosine phosphorylation of paxillin via MyD88-dependent and -independent pathways.
Journal: European journal of immunology 20030301
Title: Involvement of BDNF receptor TrkB in spatial memory formation.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20030301
Title: The pp60c-Src inhibitor PP1 is non-competitive against ATP.
Journal: FEBS letters 20030227
Title: Mechanism of v-Src- and mitogen-activated protein kinase-induced reduction of gap junction communication.
Journal: American journal of physiology. Cell physiology 20030201
Title: Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase.
Journal: American journal of physiology. Heart and circulatory physiology 20030201
Title: Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src.
Journal: The Journal of biological chemistry 20021122
Title: Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.
Journal: Oncogene 20021121
Title: Augmentation by zinc of NMDA receptor-mediated synaptic responses in CA1 of rat hippocampal slices: mediation by Src family tyrosine kinases.
Journal: Synapse (New York, N.Y.) 20021101
Title: Beta(2)-adrenergic receptor lacking the cyclic AMP-dependent protein kinase consensus sites fully activates extracellular signal-regulated kinase 1/2 in human embryonic kidney 293 cells: lack of evidence for G(s)/G(i) switching.
Journal: Molecular pharmacology 20021101
Title: Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways.
Journal: Free radical biology & medicine 20021015
Title: Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20021001
Title: Tyrosine phosphorylation of clathrin heavy chain under oxidative stress.
Journal: Biochemical and biophysical research communications 20020920
Title: Tyrosine phosphorylation of vascular endothelial cadherin and the regulation of microvascular permeability.
Journal: Surgery 20020801
Title: Distinct signals via Rho GTPases and Src drive shape changes by thrombin and sphingosine-1-phosphate in endothelial cells.
Journal: Journal of cell science 20020615
Title: CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase.
Journal: Blood 20020401
Title: A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors.
Journal: European journal of immunology 20020301
Title: Signals via FGF receptor 2 regulate migration of endothelial cells.
Journal: Biochemical and biophysical research communications 20011214
Title: Differential regulation of diverse physiological responses to VEGF in pulmonary endothelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20011201
Title: Mechanisms involved in alpha6beta1-integrin-mediated Ca(2+) signalling.
Journal: Cellular signalling 20011201
Title: PRL-induced ERalpha gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase.
Journal: Molecular endocrinology (Baltimore, Md.) 20011101
Title: Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells.
Journal: Oncogene 20011101
Title: Unexpected effects of FERM domain mutations on catalytic activity of Jak3: structural implication for Janus kinases.
Journal: Molecular cell 20011101
Title: c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.
Journal: The Journal of biological chemistry 20010511
Title: Activating Ly-49 NK receptors: central role in cytokine and chemokine production.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010415
Title: Norepinephrine induces vascular endothelial growth factor gene expression in brown adipocytes through a beta -adrenoreceptor/cAMP/protein kinase A pathway involving Src but independently of Erk1/2.
Journal: The Journal of biological chemistry 20000505
Title: Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation.
Journal: The Journal of biological chemistry 19960112
Title: Hanke JH, et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck-and FynT-dependentT cell activation. J Biol Chem. 1996 Jan 12;271(2):695-701.
Title: Duxbury MS, et al. Inhibition of SRC tyrosine kinase impairs inherent and acquired Gemcitabine resistance in human pancreatic adenocarcinoma cells. Clin Cancer Res. 2004 Apr 1;10(7):2307-18
Title: Summy JM, et al. AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes. Mol Cancer Ther. 2005 D
Title: Inoue A, et al. Phosphorylation of NMDA receptor GluN2B subunit at Tyr1472 is important for trigeminal processing of itch. Eur J Neurosci. 2016 Oct;44(7):2474-2482.
