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128270-60-0,MFCD08282793
Catalog No.:AA000XV7

128270-60-0 | Bivalirudin

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5mg
≥98%
in stock  
$89.00   $62.00
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10mg
≥98%
in stock  
$132.00   $92.00
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25mg
≥98%
in stock  
$302.00   $211.00
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50mg
≥98%
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$510.00   $357.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000XV7
Chemical Name:
Bivalirudin
CAS Number:
128270-60-0
Molecular Formula:
C98H138N24O33
Molecular Weight:
2180.2853
MDL Number:
MFCD08282793
SMILES:
CC[C@@H]([C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)Cc1ccc(cc1)O)CCC(=O)O)CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N)CCCNC(=N)N)CC(=O)N)Cc1ccccc1)CCC(=O)O)CCC(=O)O)C
Properties
Computed Properties
 
Complexity:
4950  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
16  
Heavy Atom Count:
155  
Hydrogen Bond Acceptor Count:
35  
Hydrogen Bond Donor Count:
28  
Rotatable Bond Count:
67  
XLogP3:
-7.1  

Literature

Title: Direct thrombin inhibitor-bivalirudin functionalized plasma polymerized allylamine coating for improved biocompatibility of vascular devices.

Journal: Biomaterials 20121101

Title: Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome.

Journal: Expert opinion on drug metabolism & toxicology 20121101

Title: Impact of in-hospital major bleeding on outcomes in acute coronary syndromes.

Journal: Current opinion in cardiology 20121101

Title: [New anticoagulants - direct thrombin inhibitors].

Journal: Therapeutische Umschau. Revue therapeutique 20121101

Title: Bivalirudin has its own shelf in the cath lab, eventually.

Journal: International journal of cardiology 20121018

Title: Glycoprotein IIb-IIIa inhibitors.

Journal: Cardiovascular therapeutics 20121001

Title: Comparison of bolus only with bolus plus infusion of bivalirudin in patients undergoing elective percutaneous coronary intervention: a retrospective observational study.

Journal: Journal of pharmacy practice 20121001

Title: Acute ST-elevation myocardial infarction.

Journal: Current opinion in critical care 20121001

Title: Measuring direct thrombin inhibitors with routine and dedicated coagulation assays: which assay is helpful?

Journal: American journal of clinical pathology 20121001

Title: Bivalirudin versus heparin plus a glycoprotein IIb/IIIa inhibitor in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention after clopidogrel pretreatment: pooled analysis from the ACUITY and ISAR-REACT 4 trials.

Journal: Circulation. Cardiovascular interventions 20121001

Title: Direct thrombin inhibitors for management of heparin-induced thrombocytopenia in patients receiving renal replacement therapy: comparison of clinical outcomes.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120915

Title: Heparin disrupts the CXCR4/SDF-1 axis and impairs the functional capacity of bone marrow-derived mononuclear cells used for cardiovascular repair.

Journal: Circulation research 20120914

Title: Translational success stories: development of direct thrombin inhibitors.

Journal: Circulation research 20120914

Title: Outcomes of patients with prior coronary artery bypass grafting and acute coronary syndromes: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.

Journal: JACC. Cardiovascular interventions 20120901

Title: Association between periprocedural bleeding and long-term outcomes following percutaneous coronary intervention in older patients.

Journal: JACC. Cardiovascular interventions 20120901

Title: Safety and efficacy of bivalirudin with glycoprotein IIb/IIIa for high-risk percutaneous coronary intervention.

Journal: Indian heart journal 20120901

Title: Bivalirudin: the relevance in today's interventional practice.

Journal: Indian heart journal 20120901

Title: Comparison of safety and efficacy of bivalirudin versus unfractionated heparin in high-risk patients undergoing percutaneous coronary intervention (from the Anti-Thrombotic Strategy for Reduction of Myocardial Damage During Angioplasty-Bivalirudin vs Heparin study).

Journal: The American journal of cardiology 20120815

Title: Meta-analysis comparing bivalirudin versus heparin monotherapy on ischemic and bleeding outcomes after percutaneous coronary intervention.

Journal: The American journal of cardiology 20120815

Title: Controlled reperfusion with intravenous bivalirudin and intracoronary abciximab combination therapy in the porcine myocardial infarction model.

Journal: Thrombosis research 20120801

Title: Bivalirudin is inferior to heparin in preservation of intraoperative autologous blood.

Journal: Thrombosis research 20120801

Title: Bivalirudin versus unfractionated heparin in percutaneous coronary interventions of patients having received initial fondaparinux treatment: a propensity matched study.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120801

Title: Platelet reactivity and percutaneous coronary intervention: another clue in the quest for the Holy Grail of tailored antithrombotic therapy?

Journal: Journal of the American College of Cardiology 20120731

Title: Prognostic value of a high on-clopidogrel treatment platelet reactivity in bivalirudin versus abciximab treated non-ST-segment elevation myocardial infarction patients. ISAR-REACT 4 (Intracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment-4) platelet substudy.

Journal: Journal of the American College of Cardiology 20120731

Title: GP IIb/IIIa inhibitors for STEMI: still the gold standard or an old survivor?

Journal: Current vascular pharmacology 20120701

Title: In the bivalirudin era, are we still looking for a potent antiplatelet agent?

Journal: Current vascular pharmacology 20120701

Title: What is the optimal antithrombotic strategy in primary percutaneous coronary intervention?

Journal: Current opinion in cardiology 20120701

Title: Understanding the cost-effectiveness of bivalirudin.

Journal: Heart (British Cardiac Society) 20120701

Title: Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery) score.

Journal: Journal of the American College of Cardiology 20120612

Title: New targets for anticoagulation and future perspectives.

Journal: Current drug discovery technologies 20120601

Title: New parenteral anticoagulants: focus on factor Xa and thrombin inhibitors.

Journal: Current drug discovery technologies 20120601

Title: Discovery of anticoagulant drugs: a historical perspective.

Journal: Current drug discovery technologies 20120601

Title: Effect of bivalirudin compared with unfractionated heparin plus abciximab on infarct size and myocardial recovery after primary percutaneous coronary intervention: the horizons-AMI CMRI substudy.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120601

Title: Comparative effectiveness analysis of anticoagulant strategies in a large observational database of percutaneous coronary interventions.

Journal: Journal of interventional cardiology 20120601

Title: The effect of differing pharmacologic strategies on infarct size in primary PCI--more confirmatory data for bivalirudin.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120601

Title: Alternative anticoagulation during cardiovascular procedures in pediatric patients with heparin-induced thrombocytopenia.

Journal: The journal of extra-corporeal technology 20120601

Title: Temporal trends in and factors associated with bleeding complications among patients undergoing percutaneous coronary intervention: a report from the National Cardiovascular Data CathPCI Registry.

Journal: Journal of the American College of Cardiology 20120522

Title: Clinical outcomes following stent thrombosis occurring in-hospital versus out-of-hospital: results from the HORIZONS-AMI (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction) trial.

Journal: Journal of the American College of Cardiology 20120515

Title: Cardiac surgery and heparin induced thrombocytopaenia (HIT): a case report and short review.

Journal: Heart, lung & circulation 20120501

Title: Advances in laboratory testing for thrombophilia.

Journal: American journal of hematology 20120501

Title: Feasibility and safety of transradial approach and bivalirudin treatment in elderly patients undergoing early invasive strategy for ACS: 'The OLDER Research Project' preliminary study.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20120501

Title: Direct thrombin inhibitors in cardiovascular disease.

Journal: Nature reviews. Cardiology 20120501

Title: Clinical safety of bivalirudin in patients undergoing carotid stenting.

Journal: The Journal of invasive cardiology 20120501

Title: Comparison of percutaneous coronary intervention safety before and during the establishment of a transradial program at a teaching hospital.

Journal: The American journal of cardiology 20120415

Title: Impact of anticoagulation on ionic and nonionic contrast media effect on thrombogenesis and fibrinolysis: The PEPCIT study.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120401

Title: Bivalirudin used as alternative anticoagulant in carotid artery stenting: a single center observational study.

Journal: Journal of interventional cardiology 20120401

Title: Evaluation of dose requirements for prolonged bivalirudin administration in patients with renal insufficiency and suspected heparin-induced thrombocytopenia.

Journal: Journal of thrombosis and thrombolysis 20120401

Title: Cost-effectiveness of bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitor in the treatment of acute ST-segment elevation myocardial infarction.

Journal: Heart (British Cardiac Society) 20120401

Title: Prognostic significance of elevated baseline troponin in patients with acute coronary syndromes and chronic kidney disease treated with different antithrombotic regimens: a substudy from the ACUITY trial.

Journal: Circulation. Cardiovascular interventions 20120401

Title: Cost effectiveness of anticoagulation in acute coronary syndromes.

Journal: PharmacoEconomics 20120401

Title: Bivalirudin for primary percutaneous coronary intervention in acute myocardial infarction: the HORIZONS-AMI trial.

Journal: Expert review of cardiovascular therapy 20120401

Title: Validation of the Bleeding Academic Research Consortium definition of bleeding in patients with coronary artery disease undergoing percutaneous coronary intervention.

Journal: Circulation 20120320

Title: Bivalirudin in acute myocardial infarction: NICE guidance.

Journal: Heart (British Cardiac Society) 20120301

Title: The ECG as decision support in STEMI.

Journal: Danish medical journal 20120301

Title: The prognostic meaning of the full spectrum of aVR ST-segment changes in acute myocardial infarction.

Journal: European heart journal 20120201

Title: Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Journal: Chest 20120201

Title: Treatment and prevention of heparin-induced thrombocytopenia: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Journal: Chest 20120201

Title: Glycoprotein IIb/IIIa inhibitors and bivalirudin in patients undergoing percutaneous coronary intervention.

Journal: Minerva cardioangiologica 20120201

Title: Acute stent thrombosis: technical complication or inadequate antithrombotic therapy? An optical coherence tomography study.

Journal: JACC. Cardiovascular interventions 20120201

Title: Heparin induced thrombocytopenia: case presentation and review.

Journal: Journal of clinical medicine research 20120201

Title: Prehospital treatment of patients with acute myocardial infarction with bivalirudin.

Journal: The American journal of emergency medicine 20120101

Title: Primary angioplasty in acute myocardial infarction with right bundle branch block: should new onset right bundle branch block be added to future guidelines as an indication for reperfusion therapy?

Journal: European heart journal 20120101

Title: Association between bleeding severity and long-term mortality in patients experiencing vascular complications after percutaneous coronary intervention.

Journal: The American journal of cardiology 20120101

Title: Safety of bivalirudin in patients with coronary artery disease.

Journal: Expert opinion on drug safety 20120101

Title: Incidence of bleeding in renally impaired patients receiving incorrectly dosed eptifibatide or bivalirudin while undergoing percutaneous coronary intervention.

Journal: The Annals of pharmacotherapy 20120101

Title: Recent advances in epidural analgesia.

Journal: Anesthesiology research and practice 20120101

Title: Dabigatran use in a postoperative coronary artery bypass surgery patient with nonvalvular atrial fibrillation and heparin-PF4 antibodies.

Journal: The Annals of pharmacotherapy 20120101

Title: Bivalirudin therapy is associated with improved clinical and economic outcomes in ST-elevation myocardial infarction patients undergoing percutaneous coronary intervention: results from an observational database.

Journal: Circulation. Cardiovascular quality and outcomes 20120101

Title: Efficacy and safety of enoxaparin versus unfractionated heparin during percutaneous coronary intervention: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20120101

Title: Challenges encountered with argatroban anticoagulation during cardiopulmonary bypass.

Journal: Journal of anaesthesiology, clinical pharmacology 20120101

Title: Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapy.

Journal: Cardiology research and practice 20120101

Title: Probing high affinity sequences of DNA aptamer against VEGF165.

Journal: PloS one 20120101

Title: Comparison of bivalirudin dosing strategies using total, adjusted, and ideal body weights in obese patients with heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20120101

Title: Oral antiplatelet therapy for atherothrombotic disease: overview of current and emerging treatment options.

Journal: Vascular health and risk management 20120101

Title: Translatability scoring in drug development: eight case studies.

Journal: Journal of translational medicine 20120101

Title: Outcome of the HORIZONS-AMI trial: bivalirudin enhances long-term survival in patients with ST-elevation myocardial infarction undergoing angioplasty.

Journal: Vascular health and risk management 20120101

Title: Stroke Prevention in Atrial Fibrillation: Where are We Now?

Journal: Clinical Medicine Insights. Cardiology 20120101

Title: Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response.

Journal: Clinical pharmacology : advances and applications 20120101

Title: The avantgarde carbostent in patients scheduled for undelayable noncardiac surgery.

Journal: Thrombosis 20120101

Title: Thrombus aspiration during primary percutaneous coronary intervention is associated with reduced myocardial edema, hemorrhage, microvascular obstruction and left ventricular remodeling.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20120101

Title: Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.

Journal: PloS one 20120101

Title: Current status of new anticoagulants in the management of venous thromboembolism.

Journal: Advances in hematology 20120101

Title: Hitting back HIT.

Journal: Annals of cardiac anaesthesia 20120101

Title: Distinct effects of unfractionated heparin versus bivalirudin on circulating angiogenic peptides.

Journal: PloS one 20120101

Title: Pre-emptive use of bivalirudin for emergent off-pump coronary artery bypass surgery in a suspected case of heparin-induced thrombocytopenia.

Journal: Indian journal of anaesthesia 20120101

Title: Safety and 1-year revascularization outcome of SilverHawk atherectomy in treating in-stent restenosis of femoropopliteal arteries: a retrospective review from a single center.

Journal: Cardiovascular revascularization medicine : including molecular interventions 20120101

Title: Anticoagulant and antiplatelet therapy in patients with atrial fibrillation and coronary artery disease.

Journal: Thrombosis 20120101

Title: Stent thrombosis: incidence, predictors and new technologies.

Journal: Thrombosis 20120101

Title: Dabigatran for stroke prevention in nonvalvular atrial fibrillation: answers to challenging 'real-world' questions.

Journal: Thrombosis 20120101

Title: Emerging anticoagulants.

Journal: Current medicinal chemistry 20120101

Title: Bivalirudin in combination with heparin to control mesenchymal cell procoagulant activity.

Journal: PloS one 20120101

Title: Simultaneous transradial coronary and renal in stent restenosis treatment in diabetic patient with NSTEMI complicated by hypertensive emergency.

Journal: Medical archives (Sarajevo, Bosnia and Herzegovina) 20120101

Title: Heparin-induced thrombocytopenia in the pediatric population: a review of current literature.

Journal: The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 20120101

Title: Mechanism of catheter thrombosis: comparison of the antithrombotic activities of fondaparinux, enoxaparin, and heparin in vitro and in vivo.

Journal: Blood 20111215

Title: Bivalirudin for patients with ST-elevation myocardial infarction.

Journal: Lancet (London, England) 20111203

Title: Old and new antithrombotic drugs in neonates and infants.

Journal: Seminars in fetal & neonatal medicine 20111201

Title: Loading solution prevents activation damage of human platelets before lyophilization.

Journal: Cryobiology 20111201

Title: Prasugrel and bivalirudin for primary angioplasty: early results on stent thrombosis and bleeding.

Journal: International journal of cardiology 20111201

Title: [Mortality of myocardial infarction].

Journal: Annales de cardiologie et d'angeiologie 20111201

Title: Radial access in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty in acute myocardial infarction: the HORIZONS-AMI trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201

Title: Almanac 2011: acute coronary syndromes. The national society journals present selected research that has driven recent advances in clinical cardiology.

Journal: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20111201

Title: Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction.

Journal: The New England journal of medicine 20111124

Title: Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease.

Journal: Journal of the American College of Cardiology 20111122

Title: Impact of smoking on outcomes of patients with ST-segment elevation myocardial infarction (from the HORIZONS-AMI Trial).

Journal: The American journal of cardiology 20111115

Title: Comparison of bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in patients undergoing an invasive strategy: a meta-analysis of randomized clinical trials.

Journal: International journal of cardiology 20111103

Title: Initial experience with an institutional bridging protocol for patients with recent coronary stent implantation requiring discontinuation of dual antiplatelet therapy resulting from urgent surgery.

Journal: American journal of therapeutics 20111101

Title: Novel techniques in the use of bivalirudin for cardiopulmonary bypass anticoagulation in a child with heparin-induced thrombocytopenia.

Journal: Perfusion 20111101

Title: Effect of prolonged Bivalirudin infusion on ST-segment resolution following primary percutaneous coronary intervention (from the PROBI VIRI 2 study).

Journal: The American journal of cardiology 20111101

Title: [Proteins influencing the blood coagulation].

Journal: Therapeutische Umschau. Revue therapeutique 20111101

Title: Direct thrombin inhibitors.

Journal: British journal of clinical pharmacology 20111001

Title: Outcomes of coronary arterial perforations during percutaneous coronary intervention with bivalirudin anticoagulation.

Journal: The American journal of cardiology 20111001

Title: Bivalirudin dosing adjustments for reduced renal function with or without hemodialysis in the management of heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20111001

Title: Bleeding risk comparing targeted low-dose heparin with bivalirudin in patients undergoing percutaneous coronary intervention: results from a propensity score-matched analysis of the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) registry.

Journal: Circulation. Cardiovascular interventions 20111001

Title: Incidence and predictors of heart failure following percutaneous coronary intervention in ST-segment elevation myocardial infarction: the HORIZONS-AMI trial.

Journal: American heart journal 20111001

Title: Acute coronary syndromes: Antithrombotics in ACS--moving beyond unfractionated heparin.

Journal: Nature reviews. Cardiology 20110927

Title: Unfractionated heparin administration in patients treated with bivalirudin during primary percutaneous coronary intervention is associated lower mortality and target lesion thrombosis: a report from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR).

Journal: Heart (British Cardiac Society) 20110901

Title: Optimal antithrombotic treatment during primary percutaneous coronary intervention?

Journal: Heart (British Cardiac Society) 20110901

Title: Recent advances in heparin-induced thrombocytopenia.

Journal: Current opinion in hematology 20110901

Title: Bivalirudin for anticoagulation during hypothermic cardiopulmonary bypass and recombinant factor VIIa for iatrogenic coagulopathy.

Journal: The Annals of pharmacotherapy 20110901

Title: The effect of bivalirudin on costs and outcomes of treatment of ST-segment elevation myocardial infarction.

Journal: American heart journal 20110901

Title: Endoluminal treatment of peripheral chronic total occlusions using the Crosser® recanalization catheter.

Journal: The Journal of invasive cardiology 20110901

Title: Correlation of bivalirudin dose with creatinine clearance during treatment of heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20110901

Title: Characteristics and in-hospital outcomes of patients with non-ST-segment elevation myocardial infarction and chronic kidney disease undergoing percutaneous coronary intervention.

Journal: JACC. Cardiovascular interventions 20110901

Title: Long-term impact of chronic kidney disease in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) trial.

Journal: JACC. Cardiovascular interventions 20110901

Title: Interventional cardiology: Antithrombotic drug and stent choices in primary PCI.

Journal: Nature reviews. Cardiology 20110809

Title: Safety and tolerability of high-intensity anticoagulation with bivalirudin during neuroendovascular procedures.

Journal: Neurocritical care 20110801

Title: Integrilin in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.

Journal: Journal of interventional cardiology 20110801

Title: Massive thrombosis of venous aortic coronary bypass graft treated with bivalirudin and combined technique of thrombectomy and filter distal protection.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20110801

Title: How serious a problem is bleeding in patients with acute coronary syndromes?

Journal: Current cardiology reports 20110801

Title: Is a metallic microcoil really a permanent embolic agent for the management of distal guidewire-induced coronary artery perforation?

Journal: Korean circulation journal 20110801

Title: Heparin-induced thrombocytopenia.

Journal: Clinical advances in hematology & oncology : H&O 20110801

Title: Statin effect on thrombin inhibitor effectiveness during percutaneous coronary intervention: a post-hoc analysis from the ISAR-REACT 3 trial.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20110701

Title: An assay to monitor bivalirudin levels on cardiopulmonary bypass.

Journal: The Annals of thoracic surgery 20110701

Title: Impact of diabetes mellitus on the safety and effectiveness of bivalirudin in patients with acute myocardial infarction undergoing primary angioplasty: analysis from the HORIZONS-AMI (Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction) trial.

Journal: JACC. Cardiovascular interventions 20110701

Title: Heparin plus a glycoprotein IIb/IIIa inhibitor versus bivalirudin monotherapy and paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction (HORIZONS-AMI): final 3-year results from a multicentre, randomised controlled trial.

Journal: Lancet (London, England) 20110625

Title: Effect of clopidogrel pretreatment on ischemic complications of percutaneous coronary intervention among bivalirudin-treated patients (from the EVENT registry).

Journal: The American journal of cardiology 20110615

Title: Prognostic value of the SYNTAX score in patients with acute coronary syndromes undergoing percutaneous coronary intervention: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) trial.

Journal: Journal of the American College of Cardiology 20110614

Title: Effect of switching antithrombin agents for primary angioplasty in acute myocardial infarction: the HORIZONS-SWITCH analysis.

Journal: Journal of the American College of Cardiology 20110607

Title: Clinical applications of bivalirudin in the cardiac catheterization laboratory.

Journal: Journal of cardiovascular pharmacology and therapeutics 20110601

Title: Comparison of MAX-ACT and K-ACT values when using bivalirudin anticoagulation during minimally invasive hybrid off-pump coronary artery bypass graft surgery.

Journal: Journal of cardiothoracic and vascular anesthesia 20110601

Title: Use of prolonged bivalirudin infusions following percutaneous coronary intervention.

Journal: Cardiovascular drugs and therapy 20110601

Title: Intravascular ultrasound findings of early stent thrombosis after primary percutaneous intervention in acute myocardial infarction: a Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) substudy.

Journal: Circulation. Cardiovascular interventions 20110601

Title: A randomized two-by-two comparison of high-dose bolus tirofiban versus abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary revascularization and stent placement: the tirofiban evaluation of novel dosing versus abciximab with clopidogrel and inhibition of thrombin (TENACITY) study trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601

Title: Looking back into the future: desirudin in acute coronary syndromes and coronary stenting.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110601

Title: Impact of bleeding on mortality after percutaneous coronary intervention results from a patient-level pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials.

Journal: JACC. Cardiovascular interventions 20110601

Title: Bivalirudin in contemporary percutaneous coronary intervention for non-ST-segment elevation acute coronary syndromes: what is the current role of platelet glycoprotein IIb/IIIa receptor inhibitor agents?

Journal: Critical pathways in cardiology 20110601

Title: Upstream treatment of acute coronary syndrome in the ED.

Journal: The American journal of emergency medicine 20110501

Title: Two hour bivalirudin infusion after PCI for ST elevation myocardial infarction.

Journal: Journal of thrombosis and thrombolysis 20110501

Title: [Bivalirudin as an anticoagulant during percutaneous coronary interventions in acute coronary syndromes: strengths and doubts].

Journal: Revista espanola de cardiologia 20110501

Title: The relationship between attenuated plaque identified by intravascular ultrasound and no-reflow after stenting in acute myocardial infarction: the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) trial.

Journal: JACC. Cardiovascular interventions 20110501

Title: Future anticoagulants in interventional cardiology: anti-IXa and anti-Xa agents in percutaneous coronary intervention.

Journal: Future cardiology 20110501

Title: Threshold haemoglobin levels and the prognosis of stable coronary disease: two new cohorts and a systematic review and meta-analysis.

Journal: PLoS medicine 20110501

Title: Frequency and predictors of stent thrombosis after percutaneous coronary intervention in acute myocardial infarction.

Journal: Circulation 20110426

Title: Update in hematology: heparin-induced thrombocytopenia and bivalirudin.

Journal: Journal of cardiothoracic and vascular anesthesia 20110401

Title: Bivalirudin is a dual inhibitor of thrombin and collagen-dependent platelet activation in patients undergoing percutaneous coronary intervention.

Journal: Circulation. Cardiovascular interventions 20110401

Title: Bivalirudin: a pharmacoeconomic profile of its use in patients with acute coronary syndromes.

Journal: PharmacoEconomics 20110401

Title: Pediatric catheterization laboratory anticoagulation with bivalirudin.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110401

Title: Practical viewpoints on the diagnosis and management of heparin-induced thrombocytopenia.

Journal: Seminars in thrombosis and hemostasis 20110401

Title: Glycoprotein IIb/IIIa inhibitors: do they still have a role?

Journal: Journal of the American College of Cardiology 20110308

Title: The time dependence of antithrombin initiation in patients with non-ST-segment elevation acute coronary syndromes: subgroup analysis from the ACUITY trial.

Journal: Annals of emergency medicine 20110301

Title: Bivalirudin utilization in cardiac surgery: shifting anticoagulation from indirect to direct thrombin inhibition.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20110301

Title: High-shear- and-thrombin-inducible platelet adhesion and aggregation in patients undergoing percutaneous coronary intervention. Effects of unfractionated heparin versus bivalirudin.

Journal: Thrombosis and haemostasis 20110301

Title: Adjunctive pharmacologic therapy in percutaneous coronary intervention: part II anticoagulant therapy.

Journal: Coronary artery disease 20110301

Title: Evaluation of empiric versus nomogram-based direct thrombin inhibitor management in patients with suspected heparin-induced thrombocytopenia.

Journal: American journal of hematology 20110301

Title: Use of low-dose heparin with bivalirudin for ad-hoc transradial coronary interventions: experience from a single center.

Journal: The Journal of invasive cardiology 20110301

Title: Bivalirudin and transradial access--the end of the bleeding era for catheterization procedures?

Journal: The Journal of invasive cardiology 20110301

Title: Rationale and design of the INFUSE-AMI study: A 2 × 2 factorial, randomized, multicenter, single-blind evaluation of intracoronary abciximab infusion and aspiration thrombectomy in patients undergoing percutaneous coronary intervention for anterior ST-segment elevation myocardial infarction.

Journal: American heart journal 20110301

Title: Heparin-induced thrombocytopenia and extracorporeal membrane oxygenation: a case report and review of the literature.

Journal: The journal of extra-corporeal technology 20110301

Title: Regarding changing outcomes and treatment strategies for wire-induced coronary perforations in the era of bivalirudin use. A word of caution concerning the use of bivalirudin during coronary intervention for lesions at high risk for perforation.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110215

Title: Clopidogrel pretreatment in PCI: absolute requirement or obsolete myth?

Journal: International journal of cardiology 20110203

Title: New parenteral anticoagulants in development.

Journal: Therapeutic advances in cardiovascular disease 20110201

Title: New anticoagulants in children: a review of recent studies and a look to the future.

Journal: Thrombosis research 20110201

Title: New anticoagulant agents in acute coronary syndromes.

Journal: Heart (British Cardiac Society) 20110201

Title: Antithrombotic therapy in ST-segment elevation myocardial infarction.

Journal: Expert opinion on pharmacotherapy 20110201

Title: [Direct inhibitors of thrombin, hirudin, bivalirudin, and dabigatran etexilate].

Journal: Journal des maladies vasculaires 20110201

Title: Cardiva Catalyst II vascular access management device in percutaneous diagnostic and interventional procedures with same-day discharge (Catalyst II trial).

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110201

Title: Incidence and clinical consequences of acquired thrombocytopenia after antithrombotic therapies in patients with acute coronary syndromes: results from the Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial.

Journal: American heart journal 20110201

Title: Incidence, prognostic impact, and influence of antithrombotic therapy on access and nonaccess site bleeding in percutaneous coronary intervention.

Journal: JACC. Cardiovascular interventions 20110201

Title: Direct thrombin and factor Xa inhibitors in children: a quest for new anticoagulants for children.

Journal: Wiener medizinische Wochenschrift (1946) 20110201

Title: Studies on the effects of heparin products on pregnancy-associated plasma protein A.

Journal: Clinica chimica acta; international journal of clinical chemistry 20110130

Title: Combined blockade of thrombin anion binding exosite-1 and PAR4 produces synergistic antiplatelet effect in human platelets.

Journal: Thrombosis and haemostasis 20110101

Title: A randomized pilot trial for aggressive therapeutic approaches in aspirin-resistant patients undergoing percutaneous coronary intervention.

Journal: The Journal of invasive cardiology 20110101

Title: Platelet resistance - much known and much more unknown.

Journal: The Journal of invasive cardiology 20110101

Title: Cost-effectiveness of bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitor in the treatment of non-ST-segment elevation acute coronary syndromes.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101

Title: Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium.

Journal: European heart journal 20110101

Title: Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance--the BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy.

Journal: BMC medicine 20110101

Title: A network-based multi-target computational estimation scheme for anticoagulant activities of compounds.

Journal: PloS one 20110101

Title: Heparin-induced thrombocytopenia in the ICU: an overview.

Journal: Critical care (London, England) 20110101

Title: Lepirudin as an alternative to 'heparin allergy' during cardiopulmonary bypass.

Journal: Journal of cardiothoracic surgery 20110101

Title: Heparin-induced thrombocytopenia.

Journal: Journal of emergencies, trauma, and shock 20110101

Title: Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial.

Journal: BMJ (Clinical research ed.) 20110101

Title: Dealing with thrombocytopenia during anticoagulation with heparins for active venous thromboembolism: a play-it-safe practical approach.

Journal: Therapeutics and clinical risk management 20110101

Title: Oral antiplatelet therapy in diabetes mellitus and the role of prasugrel: an overview.

Journal: Vascular health and risk management 20110101

Title: Implications of bleeding in acute coronary syndrome and percutaneous coronary intervention.

Journal: Vascular health and risk management 20110101

Title: Tissue factor, blood coagulation, and beyond: an overview.

Journal: International journal of inflammation 20110101

Title: An optimized method to assess in vivo efficacy of antithrombotic drugs using optical coherence tomography and a modified Doppler flow system.

Journal: Journal of pharmacological and toxicological methods 20110101

Title: Role of factor xa inhibitors in cancer-associated thrombosis: any new data?

Journal: Advances in hematology 20110101

Title: Emerging therapies for acute coronary syndromes.

Journal: Frontiers in pharmacology 20110101

Title: Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors.

Journal: PloS one 20110101

Title: Bivalirudin-based versus conventional heparin anticoagulation for postcardiotomy extracorporeal membrane oxygenation.

Journal: Critical care (London, England) 20110101

Title: Pharmacokinetics, pharmacodynamics, tolerability and safety of single doses of bivalirudin in healthy chinese subjects.

Journal: Biological & pharmaceutical bulletin 20110101

Title: New derivative of staphylokinase SAK-RGD-K2-Hirul exerts thrombolytic effects in the arterial thrombosis model in rats.

Journal: Pharmacological reports : PR 20110101

Title: Modeling the effects of bivalirudin in cardiac surgical patients.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20110101

Title: Signal protein-derived peptides as functional probes and regulators of intracellular signaling.

Journal: Journal of amino acids 20110101

Title: Bivalirudin use in an infant with persistent clotting on unfractionated heparin.

Journal: The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 20110101

Title: Heparin versus bivalirudin for carotid artery stenting using proximal endovascular clamping for neuroprotection: results from a prospective randomized study.

Journal: Journal of vascular surgery 20101201

Title: [Evidence-based management of ST-segment elevation myocardial infarction (STEMI). Latest guidelines of the European Society of Cardiology (ESC) 2010].

Journal: Herz 20101201

Title: Bivalirudin: a review of the pharmacology and clinical application.

Journal: Expert review of cardiovascular therapy 20101201

Title: Comparison of bivalirudin and argatroban for the management of heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20101201

Title: [Comments on the 2010 guidelines on cardiopulmonary resuscitation of the European Resuscitation Council].

Journal: Der Anaesthesist 20101201

Title: The evolving role of glycoprotein IIb/IIIa inhibitors in the setting of percutaneous coronary intervention strategies to minimize bleeding risk and optimize outcomes.

Journal: JACC. Cardiovascular interventions 20101201

Title: Comparison of bivalirudin versus heparin on radial artery occlusion after transradial catheterization.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101

Title: Safety of immediate reversal of anticoagulation by protamine to reduce bleeding complications after infarct artery stenting for acute myocardial infarction and adjunctive abciximab therapy.

Journal: Journal of thrombosis and thrombolysis 20101101

Title: M-AAA-thrombin: potent anticoagulant and antiplatelet thrombin derivative with differential affinity for factor VIII and PAR1.

Journal: Thrombosis research 20101101

Title: Oral thrombostatin FM19 inhibits prostate cancer.

Journal: Thrombosis and haemostasis 20101101

Title: Bivalirudin versus unfractionated heparin for prevention of hemofilter occlusion during continuous renal replacement therapy.

Journal: Pharmacotherapy 20101101

Title: Radial artery occlusion- a limitation of transradial catheterization.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101

Title: Impact of transfer for primary percutaneous coronary intervention on survival and clinical outcomes (from the HORIZONS-AMI Trial).

Journal: The American journal of cardiology 20101101

Title: Validation of long-term benefits of bivalirudin versus unfractionated heparin in routine clinical practice after percutaneous coronary intervention.

Journal: The American journal of cardiology 20101101

Title: Economic impact of switching to bivalirudin for a primary percutaneous coronary intervention in a US hospital.

Journal: Hospital practice (1995) 20101101

Title: Use of anticoagulant agents and risk of bleeding among patients admitted with myocardial infarction: a report from the NCDR ACTION Registry--GWTG (National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry--Get With the Guidelines).

Journal: JACC. Cardiovascular interventions 20101101

Title: The HIT treatment in a cardiac surgery patient.

Journal: International journal of cardiology 20101029

Title: Correlates and consequences of gastrointestinal bleeding complicating percutaneous coronary intervention.

Journal: The American journal of cardiology 20101015

Title: Cerebrospinal fluid drainage with bivalirudin and rFactor VIIa for thoracic aortic aneurysm surgery using left atrial-femoral artery bypass.

Journal: Journal of cardiothoracic and vascular anesthesia 20101001

Title: Bivalirudin in patients with coronary artery disease.

Journal: Cardiovascular & hematological agents in medicinal chemistry 20101001

Title: ISAR-REACT 3A: a study of reduced dose of unfractionated heparin in biomarker negative patients undergoing percutaneous coronary intervention.

Journal: European heart journal 20101001

Title: Comparison of Bivalirudin versus Bivalirudin plus glycoprotein IIb/IIIa inhibitor versus heparin plus glycoprotein IIb/IIIa inhibitor in patients with acute coronary syndromes having percutaneous intervention for narrowed saphenous vein aorto-coronary grafts (the ACUITY trial investigators).

Journal: The American journal of cardiology 20101001

Title: Efficacy and safety of bivalirudin in patients receiving clopidogrel therapy after diagnostic angiography for percutaneous coronary intervention in acute coronary syndromes.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101001

Title: It is standard practice, but is it really best practice or clinical biocreep?

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101001

Title: Rapid adoption of drug-eluting stents: clinical practices and outcomes from the early drug-eluting stent era.

Journal: American heart journal 20101001

Title: Transradial approach for coronary angiography and interventions: results of the first international transradial practice survey.

Journal: JACC. Cardiovascular interventions 20101001

Title: Surgical versus percutaneous revascularization for multivessel disease in patients with acute coronary syndromes: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.

Journal: JACC. Cardiovascular interventions 20101001

Title: Frequency and predictors of drug-eluting stent use in saphenous vein bypass graft percutaneous coronary interventions: a report from the American College of Cardiology National Cardiovascular Data CathPCI registry.

Journal: JACC. Cardiovascular interventions 20101001

Title: Successful percutaneous coronary intervention for acute coronary syndrome in a patient with severe hemophilia a.

Journal: Korean circulation journal 20101001

Title: Letter by De Servi and Navarese regarding article, 'Prognostic modeling of individual patient risk and mortality impact of ischemic and hemorrhagic complications: assessment from the Acute Catheterization and Urgent Intervention Triage Strategy trial'.

Journal: Circulation 20100921

Title: Treatment options in heparin-induced thrombocytopenia.

Journal: Current opinion in hematology 20100901

Title: Case report: a thrombus in the venous reservoir while using bivalirudin in a patient with heparin-induced thrombocytopenia undergoing heart transplantation.

Journal: Anesthesia and analgesia 20100901

Title: [Heparin-induced thrombocytopenia].

Journal: Der Internist 20100901

Title: Warfarin-induced penile necrosis in a patient with heparin-induced thrombocytopenia.

Journal: Journal of Korean medical science 20100901

Title: Bivalirudin use during radiofrequency catheter ablation procedures in two patients with a history of heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20100901

Title: Use of bivalirudin for heparin-induced thrombocytopaenia after thrombolysis in massive pulmonary embolism: a case report.

Journal: International journal of emergency medicine 20100901

Title: Prognostic value of lead V1 ST elevation during acute inferior myocardial infarction.

Journal: Circulation 20100803

Title: Balancing the benefits and risks of antiplatelet agents in patients with non-ST-segment elevated acute coronary syndromes and undergoing percutaneous coronary intervention.

Journal: Journal of thrombosis and thrombolysis 20100801

Title: A pilot, prospective evaluation of a direct thrombin inhibitor, bivalirudin (Angiomax), in patients undergoing lower extremity bypass.

Journal: Journal of vascular surgery 20100801

Title: aVR ST elevation: an important but neglected sign in ST elevation acute myocardial infarction.

Journal: European heart journal 20100801

Title: The use of bivalirudin for cardiopulmonary bypass anticoagulation in pediatric heparin-induced thrombocytopenia patients.

Journal: Artificial organs 20100801

Title: Factors influencing local and systemic levels of plasma myeloperoxidase in ST-segment elevation acute myocardial infarction.

Journal: The American journal of cardiology 20100801

Title: Case report: a 55-year-old woman with chest pain upon arrival to the emergency department.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100801

Title: Pharmacologic therapy for non ST-segment elevation acute coronary syndromes: focus on antithrombotic therapy.

Journal: Cardiovascular drugs and therapy 20100801

Title: Impact of bivalirudin therapy in high-risk patients with acute myocardial infarction: 1-year results from the HORIZONS-AMI (Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction) trial.

Journal: JACC. Cardiovascular interventions 20100801

Title: Bivalirudin in acute myocardial infarction: 'primum non nocere': the eternal dilemma: balancing risks and benefits in high-risk patients.

Journal: JACC. Cardiovascular interventions 20100801

Title: Retroperitoneal hematoma after percutaneous coronary intervention: prevalence, risk factors, management, outcomes, and predictors of mortality: a report from the BMC2 (Blue Cross Blue Shield of Michigan Cardiovascular Consortium) registry.

Journal: JACC. Cardiovascular interventions 20100801

Title: Cost-effectiveness of targeting patients undergoing percutaneous coronary intervention for therapy with bivalirudin versus heparin monotherapy according to predicted risk of bleeding.

Journal: Circulation. Cardiovascular quality and outcomes 20100701

Title: A comment on laboratory monitoring of new anticoagulants.

Journal: American journal of hematology 20100701

Title: Management of protamine allergy with bivalirudin during coronary artery revascularization.

Journal: The Annals of thoracic surgery 20100701

Title: Outcomes research: the next generation.

Journal: Circulation. Cardiovascular quality and outcomes 20100701

Title: A risk score to predict bleeding in patients with acute coronary syndromes.

Journal: Journal of the American College of Cardiology 20100608

Title: Association between use of bleeding avoidance strategies and risk of periprocedural bleeding among patients undergoing percutaneous coronary intervention.

Journal: JAMA 20100602

Title: Use of platelet glycoprotein IIb/IIIa inhibitors in diabetics undergoing PCI for non-ST-segment elevation acute coronary syndromes: impact of clinical status and procedural characteristics.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20100601

Title: Anesthetic concerns for patients with coagulopathy.

Journal: Current opinion in anaesthesiology 20100601

Title: Bivalirudin during percutaneous coronary interventions in patients with ST segment elevation myocardial infarction.

Journal: Acute cardiac care 20100601

Title: The impact of bivalirudin on percutaneous coronary intervention-related bleeding.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601

Title: Unexplained international differences in clinical outcomes after acute myocardial infarction and fibrinolytic therapy: lessons from the Hirulog and Early Reperfusion or Occlusion (HERO)-2 trial.

Journal: American heart journal 20100601

Title: Body mass index and bleeding complications after percutaneous coronary intervention: does bivalirudin make a difference?

Journal: American heart journal 20100601

Title: Antithrombotic strategy in non-ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: insights from the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry.

Journal: JACC. Cardiovascular interventions 20100601

Title: Why we do what we do? Making sense of antithrombotic therapy in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention.

Journal: JACC. Cardiovascular interventions 20100601

Title: Safety and efficacy of bivalirudin for percutaneous coronary intervention with rotational atherectomy.

Journal: Journal of interventional cardiology 20100601

Title: Bivalirudin for mechanical rotational atherectomy: the quest for better outcomes.

Journal: Journal of interventional cardiology 20100601

Title: Impact of anemia on clinical outcomes of patients with ST-segment elevation myocardial infarction in relation to gender and adjunctive antithrombotic therapy (from the HORIZONS-AMI trial).

Journal: The American journal of cardiology 20100515

Title: Bivalirudin: in patients with ST-segment elevation myocardial infarction.

Journal: Drugs 20100507

Title: Development and validation of a LC-MS/MS method for determination of bivalirudin in human plasma: Application to a clinical pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20100501

Title: Decline in platelet count in patients treated by percutaneous coronary intervention: definition, incidence, prognostic importance, and predictive factors.

Journal: European heart journal 20100501

Title: The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysis.

Journal: Thrombosis and haemostasis 20100501

Title: Comparison of bivalirudin and unfractionated heparin plus protamine in patients with coronary heart disease undergoing percutaneous coronary intervention (from the Antithrombotic Regimens aNd Outcome [ARNO] trial).

Journal: The American journal of cardiology 20100415

Title: Frequency and safety of switching antithrombin therapy at a regional PCI center.

Journal: Journal of thrombosis and thrombolysis 20100401

Title: [Clinical and economical evaluation of bivalirudin during percutaneous coronary interventions].

Journal: Annales de cardiologie et d'angeiologie 20100401

Title: Antithrombotic drugs in coronary artery disease: risk benefit ratio and bleeding.

Journal: Journal of thrombosis and haemostasis : JTH 20100401

Title: Recombinant factor VIIa to manage major bleeding from newer parenteral anticoagulants.

Journal: The Annals of pharmacotherapy 20100401

Title: Outcomes of Patients with coronary artery perforation complicating percutaneous coronary intervention and correlations with the type of adjunctive antithrombotic therapy: pooled analysis from REPLACE-2, ACUITY, and HORIZONS-AMI trials. Heparin only should be considered for lesions at high risk for perforation.

Journal: Journal of interventional cardiology 20100401

Title: Practical strategies for the management of anticoagulation therapy: unsolved issues in the cardiac catheterization laboratory.

Journal: Cardiovascular drugs and therapy 20100401

Title: Safety and effectiveness of bivalirudin in routine care of patients undergoing percutaneous coronary intervention.

Journal: European heart journal 20100301

Title: Laboratory monitoring of new anticoagulants.

Journal: American journal of hematology 20100301

Title: Which antithrombotic to use during PCI?

Journal: European heart journal 20100301

Title: Bivalirudin vs. unfractionated heparin during percutaneous coronary interventions in patients with stable and unstable angina pectoris: 1-year results of the ISAR-REACT 3 trial.

Journal: European heart journal 20100301

Title: Efficacy and safety of bivalirudin in patients with diabetes mellitus undergoing percutaneous coronary intervention in current clinical practice.

Journal: The Journal of invasive cardiology 20100301

Title: Anticoagulation during percutaneous coronary intervention in diabetics--is simpler always better?

Journal: The Journal of invasive cardiology 20100301

Title: Heparin-induced thrombocytopenia.

Journal: Seminars in cardiothoracic and vascular anesthesia 20100301

Title: Predictors of outcomes in medically treated patients with acute coronary syndromes after angiographic triage: an Acute Catheterization And Urgent Intervention Triage Strategy (ACUITY) substudy.

Journal: Circulation 20100223

Title: Treating non-ST-segment elevation acute coronary syndromes: if you aren't sure, at least do no harm.

Journal: Circulation 20100223

Title: Carotid stenting and bivalirudin with and without vascular closure: 3-year analysis of procedural outcomes.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215

Title: Heparin-induced thrombocytopenia and cardiac surgery.

Journal: Current opinion in anaesthesiology 20100201

Title: Antiplatelet and anticoagulant therapies in acute coronary syndromes.

Journal: Cardiovascular drugs and therapy 20100201

Title: Safety and in-hospital outcomes of bivalirudin use in dialysis patients undergoing percutaneous coronary intervention.

Journal: The American journal of cardiology 20100201

Title: Impact of femoral vascular closure devices and antithrombotic therapy on access site bleeding in acute coronary syndromes: The Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial.

Journal: Circulation. Cardiovascular interventions 20100201

Title: Anticoagulant therapy for percutaneous coronary intervention.

Journal: Circulation. Cardiovascular interventions 20100201

Title: In-hospital safety and effectiveness of bivalirudin in percutaneous peripheral interventions: data from a real-world registry.

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100201

Title: Commentary: bivalirudin is a safe and effective anticoagulant in the percutaneous treatment of complex infrainguinal disease.

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100201

Title: HORIZONS-AMI.

Journal: Lancet (London, England) 20100130

Title: Bleeding after percutaneous coronary intervention with Bivalirudin or unfractionated Heparin and one-year mortality.

Journal: The American journal of cardiology 20100115

Title: Prognostic modeling of individual patient risk and mortality impact of ischemic and hemorrhagic complications: assessment from the Acute Catheterization and Urgent Intervention Triage Strategy trial.

Journal: Circulation 20100105

Title: Failed pericardiocentesis for acute cardiac tamponade: two cases associated with bivalirudin administration during PCI.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100101

Title: Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials.

Journal: European heart journal 20100101

Title: Heart transplantation using bivalirudin as anticoagulant.

Journal: Interactive cardiovascular and thoracic surgery 20100101

Title: Bivalirudin: alternative anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia.

Journal: Recent patents on cardiovascular drug discovery 20100101

Title: Effect of hirulog-like peptide on balloon catheter injury-induced neointimal formation in femoral arteries of minipigs and relationship with inflammatory mediators.

Journal: Journal of vascular research 20100101

Title: Platelet thrombin receptor antagonism and atherothrombosis.

Journal: European heart journal 20100101

Title: A poly-N-acetyl glucosamine hemostatic dressing for femoral artery access site hemostasis after percutaneous coronary intervention: a pilot study.

Journal: The Journal of invasive cardiology 20100101

Title: A prospective evaluation of the safety and efficacy of the TAXUS Element paclitaxel-eluting coronary stent system for the treatment of de novo coronary artery lesions: design and statistical methods of the PERSEUS clinical program.

Journal: Trials 20100101

Title: Improving the management of non-ST elevation acute coronary syndromes: systematic evaluation of a quality improvement programme European QUality Improvement Programme for Acute Coronary Syndrome: the EQUIP-ACS project protocol and design.

Journal: Trials 20100101

Title: In-stent thrombosis after 68 months of implantation inspite of continuous dual antiplatelet therapy: a case report.

Journal: Cases journal 20100101

Title: Antithrombotic therapy in patients with coronary artery disease and with type 2 diabetes mellitus.

Journal: Wiener medizinische Wochenschrift (1946) 20100101

Title: Safety and efficacy of abciximab as an adjunct to percutaneous coronary intervention.

Journal: Vascular health and risk management 20100101

Title: Fondaparinux and acute coronary syndromes: update on the OASIS 5-6 studies.

Journal: Vascular health and risk management 20100101

Title: Heparin-induced thrombocytopenia: a practical review.

Journal: Reviews in cardiovascular medicine 20100101

Title: New options with dabigatran etexilate in anticoagulant therapy.

Journal: Vascular health and risk management 20100101

Title: Actual Role of Platelet Glycoprotein IIb/IIIa Receptor Inhibitors as Adjunctive Pharmacological Therapy to Primary Angioplasty in Acute Myocardial Infarction: In the Light of Recent Randomized Trials and Observational Studies with Bivalirudin.

Journal: The open cardiovascular medicine journal 20100101

Title: Antithrombotic strategies in patients undergoing percutaneous coronary intervention for acute coronary syndrome.

Journal: Drug design, development and therapy 20100101

Title: Argatroban in the management of heparin-induced thrombocytopenia.

Journal: Vascular health and risk management 20100101

Title: GPIIb/IIIa Receptor Antagonism Using Small Molecules Provides no Additive Long-Term Protection after Percutaneous Coronary Intervention as Compared to Clopidogrel Plus Aspirin.

Journal: The open cardiovascular medicine journal 20100101

Title: Post-operative thromboprophylaxis: new oral thrombin and factor X inhibitors and their place in clinical practice.

Journal: F1000 medicine reports 20100101

Title: Antiphospholipid syndrome; its implication in cardiovascular diseases: a review.

Journal: Journal of cardiothoracic surgery 20100101

Title: Bivalirudin: a review of pharmacology and therapeutic use.

Journal: Connecticut medicine 20100101

Title: Transradial vs femoral percutaneous coronary intervention for left main disease in octogenarians.

Journal: Indian heart journal 20100101

Title: Our technique for transradial coronary angiography and interventions.

Journal: Indian heart journal 20100101

Title: Profound thrombocytopenia after primary exposure to eptifibatide.

Journal: Drug, healthcare and patient safety 20100101

Title: The Potential Value of Near Patient Platelet Function Testing in PCI: Randomised Comparison of 600 mg versus 900 mg Clopidogrel Loading Doses.

Journal: Thrombosis 20100101

Title: Emerging antiplatelet agents, differential pharmacology, and clinical utility.

Journal: Journal of blood medicine 20100101

Title: Oral antiplatelet therapy for acute and chronic management of NSTE ACS: residual ischemic risk and opportunities for improvement.

Journal: Cardiovascular drugs and therapy 20091201

Title: Avoiding intelligence failures in the cardiac catheterization laboratory: Strategies for the safe and rational use of dalteparin or enoxaparin during percutaneous coronary intervention.

Journal: The Journal of invasive cardiology 20091201

Title: Changing outcomes and treatment strategies for wire induced coronary perforations in the era of bivalirudin use.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101

Title: Comparison of bivalirudin monotherapy versus unfractionated heparin plus tirofiban in patients with diabetes mellitus undergoing elective percutaneous coronary intervention.

Journal: The American journal of cardiology 20091101

Title: ''They can always hurt you more'' bivalirudin and the dynamic balance between bleeding and clotting.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101

Title: Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials.

Journal: European heart journal 20091101

Title: Comparison of prolonged bivalirudin infusion versus intraprocedural in preventing myocardial damage after percutaneous coronary intervention in patients with angina pectoris.

Journal: The American journal of cardiology 20091015

Title: Role of clopidogrel loading dose in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty: results from the HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trial.

Journal: Journal of the American College of Cardiology 20091006

Title: The changing horizon of acute coronary syndrome.

Journal: Lancet (London, England) 20091003

Title: Bivalirudin in patients undergoing primary angioplasty for acute myocardial infarction (HORIZONS-AMI): 1-year results of a randomised controlled trial.

Journal: Lancet (London, England) 20091003

Title: Outcomes of patients with coronary artery perforation complicating percutaneous coronary intervention and correlations with the type of adjunctive antithrombotic therapy: pooled analysis from REPLACE-2, ACUITY, and HORIZONS-AMI trials.

Journal: Journal of interventional cardiology 20091001

Title: Significantly improved vascular complications among women undergoing percutaneous coronary intervention: a report from the Northern New England Percutaneous Coronary Intervention Registry.

Journal: Circulation. Cardiovascular interventions 20091001

Title: Gastrointestinal bleeding in patients with acute coronary syndromes: incidence, predictors, and clinical implications: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.

Journal: Journal of the American College of Cardiology 20090929

Title: Otamixaban in acute coronary syndromes.

Journal: Lancet (London, England) 20090905

Title: Noncompetitive inhibitor of thrombin.

Journal: Chembiochem : a European journal of chemical biology 20090904

Title: Impact of bivalirudin on in-hospital bleeding and six-month outcomes in octogenarians undergoing percutaneous coronary intervention.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090901

Title: Heparin induced thrombocytopenia and re-thrombosis associated with warfarin and fondaparinux in a child.

Journal: Pediatric blood & cancer 20090901

Title: Oldies but goodies.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090901

Title: Bivalirudin as compared to unfractionated heparin among patients undergoing coronary angioplasty: A meta-analyis of randomised trials.

Journal: Thrombosis and haemostasis 20090901

Title: Patient satisfaction is comparable to early discharge versus overnight observation after elective percutaneous coronary intervention.

Journal: The Journal of invasive cardiology 20090901

Title: Comparison of safety and efficacy of bivalirudin versus unfractionated heparin in percutaneous peripheral intervention: a single-center experience.

Journal: JACC. Cardiovascular interventions 20090901

Title: [What's new on antithrombotics?].

Journal: Annales de cardiologie et d'angeiologie 20090801

Title: A novel hirudin derivative characterized with anti-platelet aggregations and thrombin inhibition.

Journal: Journal of thrombosis and thrombolysis 20090801

Title: Regulation of PAR-1 in patients undergoing percutaneous coronary intervention: effects of unfractionated heparin and bivalirudin.

Journal: European heart journal 20090801

Title: Safety and efficacy of a prolonged bivalirudin infusion after urgent and complex percutaneous coronary interventions: a descriptive study.

Journal: Coronary artery disease 20090801

Title: Novel anticoagulants in clinical development: focus on factor Xa and direct thrombin inhibitors.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20090801

Title: [New anticoagulants for secondary haemostasis--anti IIa inhibitors].

Journal: Hamostaseologie 20090801

Title: Safety and efficacy of bivalirudin in high-risk patients admitted through the emergency department.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20090801

Title: Impact of chronic kidney disease on early (30-day) and late (1-year) outcomes of patients with acute coronary syndromes treated with alternative antithrombotic treatment strategies: an ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) substudy.

Journal: JACC. Cardiovascular interventions 20090801

Title: Balancing potency of platelet inhibition with bleeding risk in the early treatment of acute coronary syndrome.

Journal: The western journal of emergency medicine 20090801

Title: A comparison of anticoagulation with bivalirudin and provisional GPIIb/IIIa inhibition with unfractionated heparin and mandatory GPIIb/IIIa inhibition during percutaneous coronary intervention in relation to platelet activation and the inhibition of coagulation.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801

Title: Prognostic significance of periprocedural versus spontaneously occurring myocardial infarction after percutaneous coronary intervention in patients with acute coronary syndromes: an analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.

Journal: Journal of the American College of Cardiology 20090728

Title: Intracoronary bivalirudin for no reflow reversal: a second chance to treat this disorder?

Journal: Journal of thrombosis and thrombolysis 20090701

Title: Lack of early augmentation of platelet reactivity after coronary intervention in patients treated with bivalirudin.

Journal: Journal of thrombosis and thrombolysis 20090701

Title: New antithrombotic agents in acute coronary syndromes.

Journal: Current opinion in cardiology 20090701

Title: Prefilter bivalirudin for preventing hemofilter occlusion in continuous renal replacement therapy.

Journal: The Annals of pharmacotherapy 20090701

Title: Bivalirudin as an anticoagulant for simultaneous integrated coronary artery revascularization - a novel approach to an inherent concern.

Journal: The Canadian journal of cardiology 20090701

Title: Expert consensus on treatment strategies in non- ST-segment elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention--an evidence-based review of clinical trial results and treatment guidelines from an emergency medicine perspective: report on a roundtable discussion.

Journal: The American journal of emergency medicine 20090701

Title: Feasibility and safety of prehospital administration of bivalirudin in patients with ST-elevation myocardial infarction.

Journal: The American journal of cardiology 20090615

Title: Hotline sessions presented at the American College of Cardiology Congress 2009.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20090601

Title: Direct thrombin inhibitors in patients with mechanical heart valves: ready for clinical trials?

Journal: Thrombosis and haemostasis 20090601

Title: Argatroban and bivalirudin compared to unfractionated heparin in preventing thrombus formation on mechanical heart valves. Results of an in-vitro study.

Journal: Thrombosis and haemostasis 20090601

Title: Frequency and outcomes of provisional glycoprotein IIb/IIIa blockade in patients receiving bivalirudin during percutaneous coronary intervention.

Journal: The Journal of invasive cardiology 20090601

Title: Provisional use of glycoprotein IIb/IIIa inhibitors in the era of dual antiplatelet therapy--do 'bailouts' pay off?

Journal: The Journal of invasive cardiology 20090601

Title: Hospitals with and without percutaneous coronary intervention capability: considerations for treating acute coronary syndromes.

Journal: The American journal of emergency medicine 20090601

Title: Heparin-induced thrombocytopenia. A contemporary clinical approach to diagnosis and management.

Journal: Chest 20090601

Title: Diabetes and acute coronary syndromes.

Journal: Best practice & research. Clinical endocrinology & metabolism 20090601

Title: Outcomes following pre-operative clopidogrel administration in patients with acute coronary syndromes undergoing coronary artery bypass surgery: the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial.

Journal: Journal of the American College of Cardiology 20090526

Title: Lepirudin-induced thrombocytopenia following subcutaneous administration.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090501

Title: Impact of gender and antithrombin strategy on early and late clinical outcomes in patients with non-ST-elevation acute coronary syndromes (from the ACUITY trial).

Journal: The American journal of cardiology 20090501

Title: Pharmacological and clinical profile of bivalirudin in the treatment of patients with acute coronary syndrome.

Journal: Expert opinion on drug metabolism & toxicology 20090501

Title: Choice of arterial access site and outcomes in patients with acute coronary syndromes managed with an early invasive strategy: the ACUITY trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090501

Title: Click-chemistry-conjugated oligo-angiomax in the two-dimensional DNA lattice and its interaction with thrombin.

Journal: Biomacromolecules 20090413

Title: Management of patients with unstable angina / non-ST-elevation myocardial infarction: a critical review of the 2007 ACC /AHA guidelines.

Journal: International journal of clinical practice 20090401

Title: Successful use of bivalirudin for combined carotid endarterectomy and coronary revascularization with the use of cardiopulmonary bypass in a patient with an elevated heparin-platelet factor 4 antibody titer.

Journal: Anesthesia and analgesia 20090401

Title: Antiplatelet therapy in diabetes: efficacy and limitations of current treatment strategies and future directions.

Journal: Diabetes care 20090401

Title: Cost-effectiveness analysis of anticoagulation strategies in non-ST-elevation acute coronary syndromes.

Journal: The Annals of pharmacotherapy 20090401

Title: Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.

Journal: Journal of the American College of Cardiology 20090324

Title: Abbreviated infusion of eptifibatide after successful coronary intervention The BRIEF-PCI (Brief Infusion of Eptifibatide Following Percutaneous Coronary Intervention) randomized trial.

Journal: Journal of the American College of Cardiology 20090310

Title: Resolution of a coronary embolus by intravenous application of bivalirudin.

Journal: International journal of cardiology 20090306

Title: Streamlining the design of promising clinical trials: in-vitro testing of antithrombotic regimens and multiple agonists of platelet activation.

Journal: Coronary artery disease 20090301

Title: Bivalirudin use during PCI for stent thrombosis in a patient with subacute intracranial hemorrhage.

Journal: The Journal of invasive cardiology 20090301

Title: Clinical cross-reactivity between danaparoid and heparin antibodies successfully managed with bivalirudin.

Journal: The Israel Medical Association journal : IMAJ 20090301

Title: Bioline heparin-coated ECMO with bivalirudin anticoagulation in a patient with acute heparin-induced thrombocytopenia: the immune reaction appeared to continue unabated.

Journal: Perfusion 20090301

Title: Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study.

Journal: Journal of the American College of Cardiology 20090224

Title: Early stent thrombosis in patients with acute coronary syndromes treated with drug-eluting and bare metal stents: the Acute Catheterization and Urgent Intervention Triage Strategy trial.

Journal: Circulation 20090210

Title: Relationship of QRS duration at baseline and changes over 60 min after fibrinolysis to 30-day mortality with different locations of ST elevation myocardial infarction: results from the Hirulog and Early Reperfusion or Occlusion-2 trial.

Journal: Heart (British Cardiac Society) 20090201

Title: Profile of bleeding and ischaemic complications with bivalirudin and unfractionated heparin after percutaneous coronary intervention.

Journal: European heart journal 20090201

Title: Heparin-induced thrombocytopenia: what clinicians need to know.

Journal: Thrombosis and haemostasis 20090201

Title: Bivalirudin reduces platelet and monocyte activation after elective percutaneous coronary intervention.

Journal: Thrombosis and haemostasis 20090201

Title: Pharmacotherapy of acute coronary syndrome: the ACUITY trial.

Journal: Expert opinion on pharmacotherapy 20090201

Title: HORIZONS trial: a step forward for primary percutaneous coronary intervention.

Journal: Expert review of cardiovascular therapy 20090201

Title: Impact of bivalirudin use on outcomes in nonagenarians undergoing percutaneous coronary intervention.

Journal: Journal of interventional cardiology 20090201

Title: Avoiding and managing bleeding complications in patients with non-ST-segment elevation acute coronary syndromes.

Journal: Angiology 20090101

Title: Cloning and expression of a new recombinant thrombolytic and anthithrombotic agent - a staphylokinase variant.

Journal: Acta biochimica Polonica 20090101

Title: Clinical experience with the use of bivalirudin in a large population undergoing endovascular abdominal aortic aneurysm repair.

Journal: Journal of vascular and interventional radiology : JVIR 20090101

Title: Re-evaluating risk factors for periprocedural complications during percutaneous coronary intervention in patients with unstable angina/non-ST-elevation myocardial infarction: who may benefit from more intensive antiplatelet therapy?

Journal: Current opinion in cardiology 20090101

Title: Antiplatelet intervention in acute coronary syndrome.

Journal: American journal of therapeutics 20090101

Title: Catheter-related thrombosis: biological and clinical evidence for risk with currently available anticoagulants.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20090101

Title: Use of clopidogrel in the reduction of myocardial damage during percutaneous coronary intervention.

Journal: Vascular health and risk management 20090101

Title: Bivalirudin anticoagulation during cardiac surgery: a single-center experience in 141 patients.

Journal: Perfusion 20090101

Title: Improving adjunctive pharmacotherapy for primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: beyond the HORIZONS-AMI trial.

Journal: Reviews in cardiovascular medicine 20090101

Title: Head-to-head comparison of bivalirudin versus heparin without glycoprotein IIb/IIIa inhibitors in patients with acute myocardial infarction undergoing primary angioplasty.

Journal: Cardiovascular revascularization medicine : including molecular interventions 20090101

Title: The in vitro effect of eptifibatide, a glycoprotein IIb/IIIa antagonist, on various responses of porcine blood platelets.

Journal: Acta poloniae pharmaceutica 20090101

Title: Appearance of microvascular obstruction on high resolution first-pass perfusion, early and late gadolinium enhancement CMR in patients with acute myocardial infarction.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101

Title: Selecting the optimal antithrombotic regimen for patients with acute coronary syndromes undergoing percutaneous coronary intervention.

Journal: Vascular health and risk management 20090101

Title: [Bivalirudine in heparin-induced thrombocytopenia].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101

Title: Intracoronary versus intravenous abciximab in ST-segment elevation myocardial infarction: rationale and design of the CICERO trial in patients undergoing primary percutaneous coronary intervention with thrombus aspiration.

Journal: Trials 20090101

Title: Review of the treatment of acute coronary syndrome in elderly patients.

Journal: Clinical interventions in aging 20090101

Title: Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation.

Journal: Hematology. American Society of Hematology. Education Program 20090101

Title: Eptifibatide: The evidence for its role in the management of acute coronary syndromes.

Journal: Core evidence 20090101

Title: Bivalirudin for anticoagulation in children.

Journal: Pediatric blood & cancer 20081201

Title: Differential effects of factor IIa inhibitors on the endogenous thrombin potential.

Journal: Therapeutic drug monitoring 20081201

Title: Anticoagulant characteristics of HD1-22, a bivalent aptamer that specifically inhibits thrombin and prothrombinase.

Journal: Journal of thrombosis and haemostasis : JTH 20081201

Title: Successful use of argatroban during the third trimester of pregnancy: case report and review of the literature.

Journal: Pharmacotherapy 20081201

Title: [Pharmacology of heparins and direct anticoagulants].

Journal: Hamostaseologie 20081201

Title: Emergence of new oral antithrombotics: a critical appraisal of their clinical potential.

Journal: Vascular health and risk management 20081201

Title: Influence of timing of clopidogrel treatment on the efficacy and safety of bivalirudin in patients with non-ST-segment elevation acute coronary syndromes undergoing percutaneous coronary intervention: an analysis of the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial.

Journal: JACC. Cardiovascular interventions 20081201

Title: Economic evaluation of bivalirudin with or without glycoprotein IIb/IIIa inhibition versus heparin with routine glycoprotein IIb/IIIa inhibition for early invasive management of acute coronary syndromes.

Journal: Journal of the American College of Cardiology 20081125

Title: Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase.

Journal: The Journal of pharmacology and experimental therapeutics 20081101

Title: Dabigatran etexilate: an oral direct thrombin inhibitor for prophylaxis and treatment of thromboembolic diseases.

Journal: Pharmacotherapy 20081101

Title: Successful use and dosing of bivalirudin after temporary total artificial heart implantation: a case series.

Journal: Pharmacotherapy 20081101

Title: 'Bail-out' bivalirudin use in patients with thrombotic complications unresponsive to conventional treatment during percutaneous coronary intervention.

Journal: The Journal of invasive cardiology 20081101

Title: IIb or not IIb.

Journal: Journal of the American College of Cardiology 20081007

Title: Coronary stenting with MGuard: first-in-man trial.

Journal: The Journal of invasive cardiology 20081001

Title: Percutaneous coronary intervention and the use of glycoprotein IIb/IIIa inhibitors in patients with chronic kidney disease on dialysis: a single center experience.

Journal: Hemodialysis international. International Symposium on Home Hemodialysis 20081001

Title: Comparison of bivalirudin, enoxaparin, and unfractionated heparin in preventing cardiac catheter thrombosis. Results of an in-vitro study.

Journal: Thrombosis and haemostasis 20081001

Title: The use of adjunctive anticoagulants in patients with acute coronary syndrome transitioning to percutaneous coronary intervention.

Journal: The American journal of emergency medicine 20081001

Title: [The HORIZONS-AMI trial].

Journal: Giornale italiano di cardiologia (2006) 20081001

Title: Bivalirudin reduced major bleeding and adverse events in patients with STEMI having PCI.

Journal: ACP journal club 20080916

Title: Safety and efficacy of bivalirudin with and without glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention 1-year results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial.

Journal: Journal of the American College of Cardiology 20080902

Title: [Antithrombotic therapy of acute myocardial infarction].

Journal: Der Internist 20080901

Title: Bivalirudin for patients with heparin-induced thrombocytopenia undergoing cardiovascular surgery.

Journal: The Annals of pharmacotherapy 20080901

Title: Safety, efficacy, and dosing requirements of bivalirudin in patients with heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20080901

Title: Simultaneous integrated coronary artery revascularization with long-term angiographic follow-up.

Journal: The Journal of thoracic and cardiovascular surgery 20080901

Title: Lepirudin in the management of patients with heparin-induced thrombocytopenia.

Journal: Biologics : targets & therapy 20080901

Title: Bivalirudin versus unfractionated heparin during percutaneous coronary intervention.

Journal: The New England journal of medicine 20080814

Title: Bivalirudin with provisional glycoprotein IIb/IIIa inhibitors in patients undergoing primary angioplasty in the setting of cardiogenic shock.

Journal: The American journal of cardiology 20080801

Title: Optimizing antithrombotic therapy in patients with non-ST-segment elevation acute coronary syndrome.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080801

Title: Advances in antithrombotic therapy as adjunct to reperfusion therapies for ST-segment elevation myocardial infarction.

Journal: Thrombosis and haemostasis 20080801

Title: Antons syndrome in a patient with type-2 heparin-induced thrombocytopaenia (HIT).

Journal: Acta anaesthesiologica Scandinavica 20080801

Title: Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion.

Journal: Journal of interventional cardiology 20080801

Title: Pharmacological prevention of peri-, and post-procedural myocardial injury in percutaneous coronary intervention.

Journal: Current cardiology reviews 20080801

Title: Bleeding risk and outcomes of Bivalirudin versus Glycoprotein IIb/IIIa inhibitors with targeted low-dose unfractionated Heparin in patients having percutaneous coronary intervention for either stable or unstable angina pectoris.

Journal: The American journal of cardiology 20080715

Title: Successful use of bivalirudin for superior vena cava recanalization and stent placement in a child with heparin-induced thrombocytopenia.

Journal: Pediatric cardiology 20080701

Title: Antiplatelet and anticoagulant agents: key differences in mechanisms of action, clinical application, and therapeutic benefit in patients with non-ST-segment-elevation acute coronary syndromes.

Journal: Current opinion in cardiology 20080701

Title: 2007 Guideline update for unstable angina/non-ST-segment elevation myocardial infarction: focus on antiplatelet and anticoagulant therapies.

Journal: The Annals of pharmacotherapy 20080701

Title: Low plasma fibrinogen levels with the Clauss method during anticoagulation with bivalirudin.

Journal: Anesthesiology 20080701

Title: The Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction (HORIZONS-AMI) Trial: study design and rationale.

Journal: American heart journal 20080701

Title: Treatment of ST-elevation myocardial infarction.

Journal: Future cardiology 20080701

Title: Reperfusion strategies in ST-elevation myocardial infarction--current status and perspectives for early and pre-hospital treatment.

Journal: Resuscitation 20080601

Title: [Direct thrombin inhibitors: pharmacology and application in cardiovascular anesthesia].

Journal: Der Anaesthesist 20080601

Title: Impact of bivalirudin or unfractionated heparin on platelet aggregation in patients pretreated with 600 mg clopidogrel undergoing elective percutaneous coronary intervention.

Journal: European heart journal 20080601

Title: Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Journal: Chest 20080601

Title: Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Journal: Chest 20080601

Title: Antithrombotic therapy for non-ST-segment elevation acute coronary syndromes: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Journal: Chest 20080601

Title: [The ACUITY trial: one-year results].

Journal: Giornale italiano di cardiologia (2006) 20080601

Title: The use of fondaparinux for the treatment of venous thromboembolism in a patient with heparin-induced thombocytopenia and thrombosis caused by heparin flushes.

Journal: Therapeutics and clinical risk management 20080601

Title: Percutaneous coronary intervention in patients with acute coronary syndrome: focus on bivalirudin.

Journal: Vascular health and risk management 20080601

Title: Bivalirudin during primary PCI in acute myocardial infarction.

Journal: The New England journal of medicine 20080522

Title: Antithrombotic therapy to support primary PCI.

Journal: The New England journal of medicine 20080522

Title: Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial.

Journal: Journal of the American College of Cardiology 20080506

Title: New anticoagulant agents: direct thrombin inhibitors.

Journal: Cardiology clinics 20080501

Title: What anti-thrombotic therapy is best with primary PCI for acute ST elevation myocardial infarction: how should the HORIZONS trial change current practice?

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080501

Title: Antiplatelet therapy in early management of non-ST-segment elevation acute coronary syndrome: the 2002 and 2007 guidelines from North America and Europe.

Journal: Journal of cardiovascular pharmacology 20080501

Title: Review of the 2005 American College of Cardiology, American Heart Association, and Society for Cardiovascular Interventions guidelines for adjunctive pharmacologic therapy during percutaneous coronary interventions: practical implications, new clinical data, and recommended guideline revisions.

Journal: American heart journal 20080501

Title: Off-pump exchange of short-term percutaneous ventricular assist device (VAD) to long-term implantable VAD in severe coagulopathy and multi-organ failure.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080501

Title: Bivalirudin.

Journal: Thrombosis and haemostasis 20080501

Title: [Bivalirudin and cardiac surgery: two case reports].

Journal: Giornale italiano di cardiologia (2006) 20080501

Title: The Role of Glycoprotein IIb/IIIa Inhibitors- A Promise Not Kept?

Journal: Current cardiology reviews 20080501

Title: Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.

Journal: Journal of the American College of Cardiology 20080429

Title: Current update on glycoprotein IIb-IIIa and direct thrombin inhibition in percutaneous coronary intervention for non-ST elevation acute coronary syndromes: balancing bleeding risk and antiplatelet efficacy.

Journal: Journal of interventional cardiology 20080401

Title: [Heparin induced thrombocytopenia and anticoagulation in renal replacemant therapy].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20080401

Title: Antithrombotic agents for acute coronary syndromes.

Journal: Cardiovascular & hematological agents in medicinal chemistry 20080401

Title: New anticoagulant strategies in ST elevation myocardial infarction: trials and clinical implications.

Journal: Vascular health and risk management 20080401

Title: Adjunct bivalirudin dosing protocol for neuro-endovascular procedures.

Journal: Journal of vascular and interventional neurology 20080401

Title: High-dose aprotinin effectively reduces blood loss during on-pump coronary artery bypass grafting with bivalirudin anticoagulation.

Journal: The Journal of thoracic and cardiovascular surgery 20080301

Title: Ischaemic events and bleeding in patients undergoing percutaneous coronary intervention with concomitant bivalirudin treatment.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080301

Title: Abciximab: a reappraisal of its use in coronary care.

Journal: Biologics : targets & therapy 20080301

Title: Adjunct thrombus aspiration reduces mortality in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction with high-risk angiographic characteristics.

Journal: The American journal of cardiology 20080215

Title: 'Off-label' stent therapy 2-year comparison of drug-eluting versus bare-metal stents.

Journal: Journal of the American College of Cardiology 20080212

Title: Acute left atrial thrombus after recombinant factor VIIa administration during left ventricular assist device implantation in a patient with heparin-induced thrombocytopenia.

Journal: Anesthesia and analgesia 20080201

Title: Salivating for knowledge: potential pharmacological agents in tick saliva.

Journal: PLoS medicine 20080201

Title: [Anticoagulation in acute coronary syndrome. An update].

Journal: Hamostaseologie 20080201

Title: Recent developments in acute coronary syndromes.

Journal: Clinical medicine (London, England) 20080201

Title: The laboratory diagnosis and clinical management of patients with heparin-induced thrombocytopenia: an update.

Journal: Seminars in thrombosis and hemostasis 20080201

Title: Routine use of the direct thrombin inhibitor bivalirudin for off-pump coronary artery bypass grafting is safe and effective.

Journal: The heart surgery forum 20080101

Title: Pharmacological strategies for inhibition of thrombin activity.

Journal: Current pharmaceutical design 20080101

Title: Safety and efficacy of bivalirudin in acute coronary syndromes.

Journal: Current pharmaceutical design 20080101

Title: Pharmacoeconomics of anticoagulants in acute coronary syndrome and percutaneous coronary intervention.

Journal: Current pharmaceutical design 20080101

Title: Monitoring of bivalirudin anticoagulation during and after cardiopulmonary bypass using an ecarin-activated TEG system.

Journal: Journal of cardiac surgery 20080101

Title: A novel survival model of cardioplegic arrest and cardiopulmonary bypass in rats: a methodology paper.

Journal: Journal of cardiothoracic surgery 20080101

Title: Use of bivalirudin to prevent thrombosis following orthotopic liver transplantation in a patient with Budd-Chiari syndrome and a history of heparin-induced thrombocytopenia.

Journal: Annals of clinical and laboratory science 20080101

Title: Effect of modified ultrafiltration on bivalirudin elimination and postoperative blood loss after on-pump coronary artery bypass grafting: assessment of different filtration strategies.

Journal: Journal of cardiac surgery 20080101

Title: Heparin-induced thrombocytopenia: diagnosis and management.

Journal: Thrombosis research 20080101

Title: Brave new world: the current and future use of novel anticoagulants.

Journal: Thrombosis research 20080101

Title: Antithrombotic therapies in primary angioplasty: rationale, results and future directions.

Journal: Drugs 20080101

Title: Bivalirudin: in patients with acute coronary syndromes : planned for urgent or early intervention.

Journal: Drugs 20080101

Title: New anticoagulants in children.

Journal: Hematology. American Society of Hematology. Education Program 20080101

Title: Implementing an innovative consent form: the PREDICT experience.

Journal: Implementation science : IS 20080101

Title: Quest for 'innovative strategies' in primary PCI: clot busters or devices (protection vs suction) or both? A story in search of an end.

Journal: Indian heart journal 20080101

Title: Antithrombotics for PCI: an indigenous direct thrombin inhibitor (DTI) makes the cut.

Journal: Indian heart journal 20080101

Title: Safety and efficacy of indigenously developed and manufactured bivalirudin in moderate/high-risk Indian patients undergoing percutaneous coronary intervention: the Bivaflo Registry.

Journal: Indian heart journal 20080101

Title: Antithrombotic strategies in patients with acute coronary syndromes undergoing early invasive management: one-year results from the ACUITY trial.

Journal: JAMA 20071205

Title: Thrombin-activated thrombelastography for evaluation of thrombin interaction with thrombin inhibitors.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20071201

Title: Clinical trials update from the European Society of Cardiology Congress in Vienna, 2007: PROSPECT, EVEREST, ARISE, ALOFT, FINESSE, Prague-8, CARESS in MI and ACUITY.

Journal: Cardiovascular drugs and therapy 20071201

Title: [Direct thrombin inhibition in interventional cardiology. The ACUITY trial].

Journal: Hamostaseologie 20071201

Title: Efficacy and safety of bivalirudin versus heparins in reduction of cardiac outcomes in acute coronary syndrome and percutaneous coronary interventions.

Journal: Journal of cardiovascular pharmacology and therapeutics 20071201

Title: [Gp IIb/IIIa receptor antagonists in acute coronary syndromes with no ST elevation].

Journal: Archives des maladies du coeur et des vaisseaux 20071201

Title: Focus on thrombin: alternative anticoagulants.

Journal: Seminars in cardiothoracic and vascular anesthesia 20071201

Title: Predictors and impact of major hemorrhage on mortality following percutaneous coronary intervention from the REPLACE-2 Trial.

Journal: The American journal of cardiology 20071101

Title: Survey of pharmacist-managed inpatient anticoagulation services.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20071101

Title: Drug-induced immune thrombocytopenia.

Journal: The New England journal of medicine 20071101

Title: Variegin, a novel fast and tight binding thrombin inhibitor from the tropical bont tick.

Journal: The Journal of biological chemistry 20071005

Title: Impact of bivalirudin on outcomes after percutaneous coronary revascularization with drug-eluting stents.

Journal: American heart journal 20071001

Title: Thrombin generation assay and viscoelastic coagulation monitors demonstrate differences in the mode of thrombin inhibition between unfractionated heparin and bivalirudin.

Journal: Anesthesia and analgesia 20071001

Title: Emergency percutaneous coronary intervention (PCI) for the care of patients with ST-elevation myocardial infarction (STEMI).

Journal: Minerva cardioangiologica 20071001

Title: [Heparin-induced thrombocytopenia].

Journal: Revista espanola de cardiologia 20071001

Title: [Optimizing antithrombotic therapy in non-ST-elevation acute coronary syndrome].

Journal: Revista espanola de cardiologia 20071001

Title: Does bivalirudin reduce the incidence of bleeding in patients with acute coronary syndromes undergoing PCI?

Journal: Nature clinical practice. Cardiovascular medicine 20070901

Title: Off-pump coronary artery bypass with bivalirudin for patients with heparin-induced thrombocytopenia or antiplatelet factor four/heparin antibodies.

Journal: The Annals of thoracic surgery 20070901

Title: Invited commentary.

Journal: The Annals of thoracic surgery 20070901

Title: Recombinant activated factor VII effectively reverses the anticoagulant effects of heparin, enoxaparin, fondaparinux, argatroban, and bivalirudin ex vivo as measured using thromboelastography.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070901

Title: Percutaneous coronary interventions in patients with heparin-induced thrombocytopenia.

Journal: Current cardiology reports 20070901

Title: Heparin induced thrombocytopenia: pathogenetic, clinical, diagnostic and therapeutic aspects.

Journal: Cardiovascular & hematological disorders drug targets 20070901

Title: Effects of unfractionated heparin and glycoprotein IIb/IIIa antagonists versus bivalirdin on myeloperoxidase release from neutrophils.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20070801

Title: Comparison of platelet function and morphology in patients undergoing percutaneous coronary intervention receiving bivalirudin versus unfractionated heparin versus clopidogrel pretreatment and bivalirudin.

Journal: The American journal of cardiology 20070801

Title: Pilot dose-finding and safety study of bivalirudin in infants <6 months of age with thrombosis.

Journal: Journal of thrombosis and haemostasis : JTH 20070801

Title: Direct thrombin inhibition with bivalirudin as an antithrombotic strategy in general and interventional cardiology.

Journal: Expert opinion on drug metabolism & toxicology 20070801

Title: Beyond unfractionated heparin and warfarin: current and future advances.

Journal: Circulation 20070731

Title: Influence of bivalirudin on tissue factor-triggered coagulation.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070701

Title: Monitoring direct thrombin inhibitors with a plasma diluted thrombin time.

Journal: Thrombosis and haemostasis 20070701

Title: New anticoagulant options for ST-elevation myocardial infarction and unstable angina pectoris/non-ST-elevation myocardial infarction.

Journal: Current cardiology reports 20070701

Title: Interatrial septal defect closure for cerebrovascular accidents: exploring the role of various anticoagulants.

Journal: The Journal of invasive cardiology 20070701

Title: Antithrombotic strategies in non-ST elevation acute coronary syndromes: focus on bivalirudin.

Journal: Future cardiology 20070701

Title: Association of prerandomization anticoagulant switching with bleeding in the setting of percutaneous coronary intervention (A REPLACE-2 analysis).

Journal: The American journal of cardiology 20070615

Title: Variations in the use of emergency PCI for the treatment of re-infarction following intravenous fibrinolytic therapy: impact on outcomes in HERO-2.

Journal: European heart journal 20070601

Title: Managing acute coronary syndrome: evidence-based approaches.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070601

Title: Temporal trends, safety, and efficacy of bivalirudin in elective percutaneous coronary intervention: insights from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium.

Journal: Journal of interventional cardiology 20070601

Title: Effect of anemia on hemorrhagic complications and mortality following percutaneous coronary intervention.

Journal: The American journal of cardiology 20070601

Title: Fondaparinux as a treatment option for heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20070601

Title: The direct thrombin inhibitor argatroban: a review of its use in patients with and without HIT.

Journal: Biologics : targets & therapy 20070601

Title: Bleeding and blood transfusion issues in patients with non-ST-segment elevation acute coronary syndromes.

Journal: European heart journal 20070501

Title: Comparison of patient outcomes with bivalirudin versus unfractionated heparin in percutaneous coronary intervention.

Journal: Pharmacotherapy 20070501

Title: Successful use of bivalirudin as anticoagulant for ECMO in a patient with acute HIT.

Journal: The Annals of thoracic surgery 20070501

Title: The safety of a bivalirudin-based approach in patients undergoing rotational atherectomy.

Journal: The Journal of invasive cardiology 20070501

Title: Anticoagulant therapy in acute coronary syndromes.

Journal: Future cardiology 20070501

Title: Heparin resistance in acute coronary syndromes.

Journal: Journal of thrombosis and thrombolysis 20070401

Title: Heparin-induced thrombocytopenia: treatment options and special considerations.

Journal: Pharmacotherapy 20070401

Title: Impact of smart infusion technology on administration of anticoagulants (unfractionated Heparin, Argatroban, Lepirudin, and Bivalirudin).

Journal: The American journal of cardiology 20070401

Title: Enoxaparin injection for the treatment of high-risk patients with non-ST elevation acute coronary syndrome.

Journal: Vascular health and risk management 20070401

Title: Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: an analysis from the ACUITY Trial.

Journal: Journal of the American College of Cardiology 20070327

Title: ACUITY-PCI: one drug does not fit all.

Journal: Lancet (London, England) 20070317

Title: Bivalirudin in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a subgroup analysis from the Acute Catheterization and Urgent Intervention Triage strategy (ACUITY) trial.

Journal: Lancet (London, England) 20070317

Title: Bivalirudin in acute coronary syndromes.

Journal: The New England journal of medicine 20070308

Title: Bivalirudin in acute coronary syndromes.

Journal: The New England journal of medicine 20070308

Title: Differential effects of direct thrombin inhibitors and antithrombin-dependent anticoagulants on the dynamics of clot formation.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070301

Title: Current incidence and clinical outcomes of bivalirudin administration among patients undergoing primary coronary intervention for stent thrombosis elevation acute myocardial infarction.

Journal: Coronary artery disease 20070301

Title: Transradial approach for carotid artery stenting: a feasibility study.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215

Title: Bivalirudin during cardiopulmonary bypass in patients with previous or acute heparin-induced thrombocytopenia and heparin antibodies: results of the CHOOSE-ON trial.

Journal: The Annals of thoracic surgery 20070201

Title: Effect of combined anticoagulation using heparin and bivalirudin on the hemostatic and inflammatory responses to cardiopulmonary bypass in the rat.

Journal: Anesthesiology 20070201

Title: Bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in drug-eluting stent implantations in the absence of acute myocardial infarction: clinical and economic results.

Journal: The Journal of invasive cardiology 20070201

Title: Bivalirudin and DES: a PCI strategy that pays.

Journal: The Journal of invasive cardiology 20070201

Title: Alternative anticoagulation management strategies for the patient with heparin-induced thrombocytopenia undergoing cardiac surgery.

Journal: Journal of cardiothoracic and vascular anesthesia 20070201

Title: Direct thrombin inhibition during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.

Journal: Expert review of cardiovascular therapy 20070101

Title: Deep hypothermic circulatory arrest and bivalirudin use in a patient with heparin-induced thrombocytopenia and antiphospholipid syndrome.

Journal: Journal of cardiac surgery 20070101

Title: First human case description of TandemHeart-assisted high-risk percutaneous balloon aortic valvuloplasty using bivalirudin anticoagulation.

Journal: The Journal of invasive cardiology 20070101

Title: [The best of thrombosis in 2006].

Journal: Archives des maladies du coeur et des vaisseaux 20070101

Title: Bivalirudin anticoagulation for cardiopulmonary bypass: an unusual case.

Journal: Texas Heart Institute journal 20070101

Title: Blood pressure and risks of vascular complications after percutaneous coronary intervention.

Journal: Dimensions of critical care nursing : DCCN 20070101

Title: Severe heparin-induced thrombocytopenia: when the obvious is not obvious, a case report.

Journal: Journal of medical case reports 20070101

Title: Evidence-based medical therapy of patients with acute coronary syndromes.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101

Title: Similar success rates with bivalirudin and unfractionated heparin in bare-metal stent implantation.

Journal: Cardiovascular and interventional radiology 20070101

Title: Sulodexide for hemodialysis anticoagulation in heparin-induced thrombocytopenia type II.

Journal: Journal of nephrology 20070101

Title: Interventional cardiology in Israel at 2005 - state of practice.

Journal: Acute cardiac care 20070101

Title: Use of activated recombinant factor VII for severe coagulopathy post ventricular assist device or orthotopic heart transplant.

Journal: Journal of cardiothoracic surgery 20070101

Title: Successful use of bivalirudin for cardiopulmonary bypass in a patient with heparin allergy.

Journal: Perfusion 20070101

Title: Heparin-induced thrombocytopenia: a general review.

Journal: Journal of infusion nursing : the official publication of the Infusion Nurses Society 20070101

Title: Direct antithrombins: mechanisms, trials, and role in contemporary interventional medicine.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101

Title: Anticoagulation for acute coronary syndromes: from heparin to direct thrombin inhibitors.

Journal: Reviews in cardiovascular medicine 20070101

Title: The use of antithrombotics for acute coronary syndromes in the emergency department: considerations and impact.

Journal: Progress in cardiovascular diseases 20070101

Title: Endovascular treatment of a renal artery stenosis: techniques, indications, results. Role of embolic protection devices (part 2).

Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20070101

Title: Glycoprotein IIb/IIIa inhibitors: questioning indications and treatment algorithms.

Journal: Cardiovascular revascularization medicine : including molecular interventions 20070101

Title: The safety of bivalirudin during elective percutaneous coronary interventions in heart transplant patients.

Journal: Cardiology journal 20070101

Title: [Anticoagulant therapy and cardiopulmonary bypass].

Journal: Archivos de cardiologia de Mexico 20070101

Title: Bivalirudin: a new promising direct antithrombin.

Journal: Indian heart journal 20070101

Title: Heparin induced thrombocytopenia management with bivalirudin.

Journal: Indian heart journal 20070101

Title: Heparin-induced thrombocytopenia.

Journal: The New England journal of medicine 20061214

Title: Bivalirudin in percutaneous coronary intervention.

Journal: Vascular health and risk management 20061201

Title: Fondaparinux in the management of patients with ST-elevation acute myocardial infarction.

Journal: Vascular health and risk management 20061201

Title: Bivalirudin for patients with acute coronary syndromes.

Journal: The New England journal of medicine 20061123

Title: Accounting for ACUITY.

Journal: The New England journal of medicine 20061123

Title: Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin.

Journal: Heart (British Cardiac Society) 20061101

Title: Bolus-only platelet glycoprotein IIb-IIIa inhibition during percutaneous coronary intervention.

Journal: The Journal of invasive cardiology 20061101

Title: Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061101

Title: Angiographic and clinical outcomes of bivalirudin versus heparin in patients with acute coronary syndrome undergoing percutaneous coronary intervention.

Journal: The Canadian journal of cardiology 20061101

Title: Heparin-induced thrombocytopenia: a review.

Journal: Seminars in thrombosis and hemostasis 20061101

Title: Comparative cost-effectiveness of anticoagulation with bivalirudin or heparin with and without a glycoprotein IIb/IIIa-receptor inhibitor in patients undergoing percutaneous coronary intervention in Sweden: a decision-analytic model.

Journal: Clinical therapeutics 20061101

Title: [Clinical use of a new class of anticoagulant drugs: the direct thrombin inhibitors].

Journal: Giornale italiano di cardiologia (2006) 20061101

Title: Recent developments in antithrombotic therapy: will sodium warfarin be a drug of the past?

Journal: Recent patents on cardiovascular drug discovery 20061101

Title: Successful percutaneous coronary intervention using bivalirudin in a patient with chronic lymphocytic leukemia and thrombocytopenia.

Journal: European journal of haematology 20061001

Title: Debate of adjunctive pharmacology for percutaneous coronary intervention: anticoagulation and clopidogrel are not (always) enough.

Journal: Journal of interventional cardiology 20061001

Title: Debate of adjunctive pharmacology for percutaneous coronary intervention: thrombin inhibitors and clopidogrel are enough.

Journal: Journal of interventional cardiology 20061001

Title: [Bivalirudin: a direct thrombin inhibitor in percutaneous coronary interventions].

Journal: Ugeskrift for laeger 20060918

Title: Direct thrombin inhibition appears to be a safe and effective anticoagulant for percutaneous bypass graft interventions.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901

Title: Bivalirudin provides rapid, effective, and reliable anticoagulation during off-pump coronary revascularization: results of the 'EVOLUTION OFF' trial.

Journal: Anesthesia and analgesia 20060901

Title: Risk stratification of patients with acute anterior myocardial infarction and right bundle-branch block: importance of QRS duration and early ST-segment resolution after fibrinolytic therapy.

Journal: Circulation 20060822

Title: Successful anticoagulation with bivalirudin in antithrombin-deficient pediatric patient undergoing stent placement.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060801

Title: Greater inhibitory effects of bivalirudin compared with unfractionated heparin plus eptifibitide on thrombin-induced platelet activation.

Journal: Coronary artery disease 20060801

Title: Switching from Enoxaparin to Bivalirudin in Patients with Acute Coronary Syndromes without ST-segment Elevation who Undergo Percutaneous Coronary Intervention. Results from SWITCH--a multicenter clinical trial.

Journal: The Journal of invasive cardiology 20060801

Title: Clinical end point definitions after percutaneous coronary intervention and their relationship to late mortality: an assessment by attributable risk.

Journal: Heart (British Cardiac Society) 20060701

Title: Heparin-induced thrombocytopenia and cardiovascular diseases.

Journal: American heart journal 20060701

Title: Outcomes of patients with acute coronary syndromes who are treated with bivalirudin during percutaneous coronary intervention: an analysis from the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE-2) trial.

Journal: American heart journal 20060701

Title: Provisional glycoprotein IIb/IIIa blockade in a randomized investigation of bivalirudin versus heparin plus planned glycoprotein IIb/IIIa inhibition during percutaneous coronary intervention: predictors and outcome in the Randomized Evaluation in Percutaneous coronary intervention Linking Angiomax to Reduced Clinical Events (REPLACE)-2 trial.

Journal: American heart journal 20060701

Title: Initial Q waves accompanying ST-segment elevation at presentation of acute myocardial infarction and 30-day mortality in patients given streptokinase therapy: an analysis from HERO-2.

Journal: Lancet (London, England) 20060624

Title: A randomized trial to evaluate the relative protection against post-percutaneous coronary intervention microvascular dysfunction, ischemia, and inflammation among antiplatelet and antithrombotic agents: the PROTECT-TIMI-30 trial.

Journal: Journal of the American College of Cardiology 20060620

Title: The future of an illusion.

Journal: Journal of the American College of Cardiology 20060620

Title: Planned versus provisional use of glycoprotein IIb/IIIa inhibitors in smokers undergoing percutaneous coronary intervention.

Journal: The American journal of cardiology 20060615

Title: Bivalirudin for anticoagulation in mechanical aortic valve replacement and heparin-induced thrombocytopenia.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20060601

Title: Angiographic adverse events, creatine kinase-MB elevation, and ischemic end points complicating percutaneous coronary intervention (a REPLACE-2 substudy).

Journal: The American journal of cardiology 20060601

Title: Argatroban, bivalirudin, and lepirudin do not decrease clot propagation and strength as effectively as heparin-activated antithrombin in vitro.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601

Title: Bivalirudin anticoagulation for a patient with hypercoagulable immune syndromes undergoing mitral valve surgery.

Journal: The Annals of thoracic surgery 20060601

Title: Bivalirudin in peripheral interventions.

Journal: Techniques in vascular and interventional radiology 20060601

Title: Comparison of effects of bare metal versus drug-eluting stent implantation on biomarker levels following percutaneous coronary intervention for non-ST-elevation acute coronary syndrome.

Journal: The American journal of cardiology 20060515

Title: Measurement of patients' bivalirudin plasma levels by a thrombelastograph ecarin clotting time assay: a comparison to a standard activated clotting time.

Journal: Anesthesia and analgesia 20060501

Title: Cost-effectiveness analysis of antithrombotic therapy in nonurgent percutaneous coronary intervention.

Journal: Pharmacotherapy 20060501

Title: The vulnerable endothelium: priming the vascular endothelium for thrombosis with unfractionated heparin: biologic plausibility for observations from the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial (Am J Heart 2005;150:189-92).

Journal: American heart journal 20060501

Title: Ischemic and bleeding outcomes in women treated with bivalirudin during percutaneous coronary intervention: a subgroup analysis of the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE)-2 trial.

Journal: American heart journal 20060501

Title: Evaluation of bivalirudin treatment for heparin-induced thrombocytopenia in critically ill patients with hepatic and/or renal dysfunction.

Journal: Pharmacotherapy 20060401

Title: Evaluation of treatment with direct thrombin inhibitors in patients with heparin-induced thrombocytopenia.

Journal: Pharmacotherapy 20060401

Title: Frequency of recurrent ST-elevation myocardial infarction after fibrinolytic therapy in a different territory as a manifestation of multiple unstable coronary arterial plaques.

Journal: The American journal of cardiology 20060401

Title: Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis.

Journal: Circulation 20060307

Title: Clinical development of bivalirudin (Angiox): rationale for thrombin-specific anticoagulation in percutaneous coronary intervention and acute coronary syndromes.

Journal: International journal of clinical practice 20060301

Title: Anticoagulation for cardiopulmonary bypass: is a replacement for heparin on the horizon?

Journal: The Journal of thoracic and cardiovascular surgery 20060301

Title: A comparison of bivalirudin to heparin with protamine reversal in patients undergoing cardiac surgery with cardiopulmonary bypass: the EVOLUTION-ON study.

Journal: The Journal of thoracic and cardiovascular surgery 20060301

Title: Anticoagulation with bivalirudin for off-pump coronary artery bypass grafting: the results of the EVOLUTION-OFF study.

Journal: The Journal of thoracic and cardiovascular surgery 20060301

Title: Anti-thrombotic effect of bivalirudin compared with eptifibatide and unfractionated heparin in diabetic patients: an ex vivo human study.

Journal: Thrombosis and haemostasis 20060301

Title: Transitioning from heparin to bivalirudin in patients undergoing ad hoc transradial interventional procedures: a pilot study.

Journal: The Journal of invasive cardiology 20060301

Title: Use of bivalirudin as the foundation anticoagulant during percutaneous peripheral interventions.

Journal: The Journal of invasive cardiology 20060301

Title: Emerging anticoagulants: mechanism of action and future potential.

Journal: Vnitrni lekarstvi 20060301

Title: Thrombin inhibitors and cardiopulmonary bypass.

Journal: The journal of extra-corporeal technology 20060301

Title: Platelet inhibitors in non-ST-segment elevation acute coronary syndromes and percutaneous coronary intervention: glycoprotein IIb/IIIa inhibitors, clopidogrel, or both?

Journal: Vascular health and risk management 20060301

Title: Treatment of heparin-induced thrombocytopenia in cardiovascular patients.

Journal: Expert opinion on pharmacotherapy 20060201

Title: Bivalirudin use in carotid endarterectomy in a patient with heparin-induced thrombocytopenia.

Journal: The Annals of pharmacotherapy 20060201

Title: Case 1-2006: off-pump coronary artery bypass graft surgery anticoagulation with bivalirudin: a patient with heparin-induced thrombocytopenia syndrome type II and renal failure.

Journal: Journal of cardiothoracic and vascular anesthesia 20060201

Title: Treatment of heparin-induced thrombocytopenia: is there a role for bivalirudin?

Journal: Pharmacotherapy 20060201

Title: [Mechanism of thrombosis: physiopathology, role of thrombin and its inhibition by modern therapies].

Journal: Archives des maladies du coeur et des vaisseaux 20060201

Title: [Direct thrombin inhibitors in coronary angioplasty. Value of bivalirudin ].

Journal: Archives des maladies du coeur et des vaisseaux 20060201

Title: [Present and future developments of antithrombotic agents].

Journal: Archives des maladies du coeur et des vaisseaux 20060201

Title: [Antithrombotic agents in clinical practice].

Journal: Archives des maladies du coeur et des vaisseaux 20060201

Title: Use of bivalirudin to treat heparin-induced thrombocytopenia in a patient with idiopathic giant-cell myocarditis.

Journal: Connecticut medicine 20060201

Title: Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance.

Journal: Journal of the American College of Cardiology 20060103

Title: Increased expression of platelet P-selectin and formation of platelet-leukocyte aggregates in blood from patients treated with unfractionated heparin plus eptifibatide compared with bivalirudin.

Journal: Thrombosis research 20060101

Title: Inhibition of thrombin: relevance to anti-thrombosis strategy.

Journal: Frontiers in bioscience : a journal and virtual library 20060101

Title: Prognostic differences between different types of bundle branch block during the early phase of acute myocardial infarction: insights from the Hirulog and Early Reperfusion or Occlusion (HERO)-2 trial.

Journal: European heart journal 20060101

Title: [The management of patients with heparin-induced thrombocytopenia].

Journal: Hamostaseologie 20060101

Title: Heparin-induced thrombocytopenia and cardiovascular patients: recognition and treatment.

Journal: Progress in cardiovascular nursing 20060101

Title: Cardiopulmonary bypass for complex cardiac surgery using bivalirudin anticoagulation in a patient with heparin antibodies.

Journal: Journal of cardiac surgery 20060101

Title: When heparin causes thrombosis: significance, recognition, and management of heparin-induced thrombocytopenia in dialysis patients.

Journal: Seminars in dialysis 20060101

Title: Bivalirudin versus unfractionated heparin in patients undergoing percutaneous coronary intervention after acute myocardial infarction.

Journal: Cardiovascular revascularization medicine : including molecular interventions 20060101

Title: New anticoagulants.

Journal: Hematology. American Society of Hematology. Education Program 20060101

Title: A comparative study on the cost of new antibiotics and drugs of other therapeutic categories.

Journal: PloS one 20060101

Title: Practical guidelines for the use of anticoagulants in the catheterization laboratory.

Journal: Reviews in cardiovascular medicine 20060101

Title: Bivalirudin in acute coronary syndromes and percutaneous coronary intervention.

Journal: Reviews in cardiovascular medicine 20060101

Title: Platelet protagonist/antagonist: understanding the distinguishing characteristics of anticoagulants.

Journal: Reviews in cardiovascular medicine 20060101

Title: Economic implications of bivalirudin in the cardiac catheterization laboratory.

Journal: Reviews in cardiovascular medicine 20060101

Title: Evolving antithrombotic treatment strategies for acute ST-elevation myocardial infarction.

Journal: Reviews in cardiovascular medicine 20060101

Title: Carotid artery stenting with neuroprotection: assessing the learning curve and treatment outcome.

Journal: American journal of surgery 20051201

Title: Bivalirudin anticoagulation for cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20051201

Title: Bivalirudin vs heparin in percutaneous coronary intervention: a pooled analysis.

Journal: Journal of cardiovascular pharmacology and therapeutics 20051201

Title: Bivalirudin: role in current percutaneous coronary intervention practice.

Journal: British journal of hospital medicine (London, England : 2005) 20051201

Title: [Direct and indirect antithrombins in acute coronary syndromes].

Journal: Wiener klinische Wochenschrift 20051201

Title: Sensitivity of a modified ACT test to levels of bivalirudin used during cardiac surgery.

Journal: The journal of extra-corporeal technology 20051201

Title: Differences in the clinically effective molar concentrations of four direct thrombin inhibitors explain their variable prothrombin time prolongation.

Journal: Thrombosis and haemostasis 20051101

Title: Adjunctive Antiplatelet / Antithrombotic therapy in percutaneous coronary intervention.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20051101

Title: Bivalirudin: a direct thrombin inhibitor used during percutaneous coronary intervention.

Journal: Future cardiology 20051101

Title: Percutaneous coronary intervention-related bleeding risk factors in current practice.

Journal: The Annals of pharmacotherapy 20051001

Title: Presence of direct thrombin inhibitors can affect the results and interpretation of lupus anticoagulant testing.

Journal: American journal of clinical pathology 20051001

Title: Brachytherapy and bivalirudin evaluation study.

Journal: American heart journal 20051001

Title: The effects of bivalirudin compared with those of unfractionated heparin plus eptifibatide on inflammation and thrombin generation and activity during coronary intervention.

Journal: Coronary artery disease 20050901

Title: Effectiveness of the concomitant use of bivalirudin and drug-eluting stents (from the prospective, multicenter BivAlirudin and Drug-Eluting STents [ADEST] study).

Journal: The American journal of cardiology 20050901

Title: Bivalirudin as an anticoagulation agent: safety and efficacy in peripheral interventions.

Journal: Journal of vascular and interventional radiology : JVIR 20050901

Title: Heparin and other rapidly acting anticoagulants.

Journal: Seminars in vascular surgery 20050901

Title: Drug insight: bleeding after percutaneous coronary intervention-risks, measures and impact of anticoagulant treatment options.

Journal: Nature clinical practice. Cardiovascular medicine 20050901

Title: Use of bivalirudin as an anticoagulant during cardiopulmonary bypass.

Journal: The journal of extra-corporeal technology 20050901

Title: [Haemostaseology].

Journal: Der Internist 20050801

Title: Routine bivalirudin use in percutaneous carotid interventions.

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20050801

Title: A safety and feasibility report of combined direct thrombin and GP IIb/IIIa inhibition with bivalirudin and tirofiban in peripheral vascular disease intervention: treating critical limb ischemia like acute coronary syndrome.

Journal: The Journal of invasive cardiology 20050801

Title: New antithrombotics in the prevention of thromboembolic disease.

Journal: European journal of internal medicine 20050801

Title: Should bivalirudin be the anticoagulant of choice for percutaneous coronary intervention?

Journal: Nature clinical practice. Cardiovascular medicine 20050801

Title: Patients with prolonged ischemic chest pain and presumed-new left bundle branch block have heterogeneous outcomes depending on the presence of ST-segment changes.

Journal: Journal of the American College of Cardiology 20050705

Title: Preemptive use of bivalirudin for urgent on-pump coronary artery bypass grafting in patients with potential heparin-induced thrombocytopenia.

Journal: The Annals of thoracic surgery 20050701

Title: Invited commentary.

Journal: The Annals of thoracic surgery 20050701

Title: Bivalirudin versus heparin as an antithrombotic agent in patients who undergo percutaneous saphenous vein graft intervention with a distal protection device.

Journal: The American journal of cardiology 20050701

Title: Direct thrombin inhibitors.

Journal: Current cardiology reports 20050701

Title: Predictors of in-hospital and 30-day complications of peripheral vascular interventions using bivalirudin as the primary anticoagulant: results from the APPROVE Registry.

Journal: The Journal of invasive cardiology 20050701

Title: Bivalirudin as an adjunct to acute coronary intervention in post-operative myocardial infarction.

Journal: The Journal of invasive cardiology 20050701

Title: Successful percutaneous coronary intervention in a patient with severe haemophilia A using bivalirudin as the sole procedural anticoagulant.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia 20050701

Title: Bivalirudin: a review.

Journal: Expert opinion on pharmacotherapy 20050701

Title: Evolving management strategies for heparin-induced thrombocytopenia.

Journal: Seminars in hematology 20050701

Title: Update on heparin-induced thrombocytopenia and cardiovascular interventions.

Journal: Seminars in hematology 20050701

Title: Use of bivalirudin during percutaneous coronary intervention in patients with diabetes mellitus: an analysis from the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (REPLACE)-2 trial.

Journal: Journal of the American College of Cardiology 20050621

Title: Inhibition of platelet aggregation with eptifibatide, bivalirudin, and heparin in patients undergoing percutaneous coronary intervention receiving clopidogrel pretreatment (The PharmacoDynamic Evaluation of Angiomax, Clopidogrel with or without INtegrilin [DEACON] study).

Journal: The American journal of cardiology 20050615

Title: Assessment of hemostatic activation during cardiopulmonary bypass for coronary artery bypass grafting with bivalirudin: results of a pilot study.

Journal: The Journal of thoracic and cardiovascular surgery 20050601

Title: What is the learning curve for carotid artery stenting with neuroprotection? Analysis of 200 consecutive cases at an academic institution.

Journal: Perspectives in vascular surgery and endovascular therapy 20050601

Title: [Direct inhibition of thrombin. A new strategy for the treatment of atrial fibrillation and acute coronary syndrome?].

Journal: Herz 20050501

Title: Safety and feasibility of Bivalirudin with either Cypher and Taxus drug-eluting stent during percutaneous coronary intervention.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20050501

Title: Effectiveness and safety of bivalirudin during percutaneous coronary intervention in a single medical center.

Journal: The American journal of cardiology 20050315

Title: Bivalirudin versus heparin and glycoprotein IIb/IIIa inhibition among patients with renal impairment undergoing percutaneous coronary intervention (a subanalysis of the REPLACE-2 trial).

Journal: The American journal of cardiology 20050301

Title: Optimizing management of hirudin anticoagulation.

Journal: The journal of extra-corporeal technology 20050301

Title: Diagnosis and management of heparin-induced thrombocytopenia.

Journal: Expert review of cardiovascular therapy 20050301

Title: PCI with bivalirudin and provisional GP IIb/IIIa inhibition is more cost-effective than heparin plus routine GP IIb/IIIa inhibition. Commentary.

Journal: Evidence-based cardiovascular medicine 20050301

Title: New anticoagulants for the prevention and treatment of venous thromboembolism.

Journal: Vascular health and risk management 20050301

Title: Eptifibatide-associated acute, profound thrombocytopenia.

Journal: The Annals of pharmacotherapy 20050201

Title: Direct thrombin inhibitors (part 2 of 2).

Journal: The Journal of invasive cardiology 20050201

Title: Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050201

Title: Complications in peripheral vascular interventions: emerging role of direct thrombin inhibitors.

Journal: Journal of vascular and interventional radiology : JVIR 20050201

Title: Heparin-induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050101

Title: Thrombin, an ideal target for pharmacological inhibition: a review of direct thrombin inhibitors.

Journal: American heart journal 20050101

Title: Thrombin-directed inhibitors: pharmacology and clinical use.

Journal: American heart journal 20050101

Title: [The best of thrombosis in 2004].

Journal: Archives des maladies du coeur et des vaisseaux 20050101

Title: Safety of bivalirudin during percutaneous coronary interventions in patients with abnormal renal function.

Journal: International journal of cardiovascular interventions 20050101

Title: Anticoagulation management and cardiac surgery in patients with heparin-induced thrombocytopenia.

Journal: Seminars in thoracic and cardiovascular surgery 20050101

Title: Bivalirudin: a review of its use in patients undergoing percutaneous coronary intervention.

Journal: Drugs 20050101

Title: Anticoagulant use in patients with chronic renal impairment.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

Title: Antiplatelet agents in patients undergoing percutaneous coronary intervention: how many and how much?

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

Title: Adoption of Angiomax at Christus Santa Rosa Medical Center decreases costs and increases satisfaction.

Journal: The Journal of cardiovascular management : the official journal of the American College of Cardiovascular Administrators 20050101

Title: Heparin-induced thrombocytopenia: an update.

Journal: Thrombosis journal 20050101

Title: New trends in anticoagulant treatments.

Journal: Lupus 20050101

Title: Bivalirudin compared with IIb/IIIa inhibitors in patients with in-stent restenosis undergoing intracoronary brachytherapy.

Journal: Cardiovascular revascularization medicine : including molecular interventions 20050101

Title: Intracoronary macrothrombus formation during percutaneous coronary intervention despite optimal activated clotting time using bivalirudin--a case report.

Journal: Angiology 20050101

Title: A successful anticoagulation protocol for the first HeartMate II implantation in the United States.

Journal: Texas Heart Institute journal 20050101

Title: Bivalirudin: pharmacology and clinical applications.

Journal: Cardiovascular drug reviews 20050101

Title: Severe argatroban-induced coagulopathy in a patient with a history of heparin-induced thrombocytopenia.

Journal: The Annals of thoracic surgery 20041201

Title: Cardiopulmonary bypass with bivalirudin in type II heparin-induced thrombocytopenia.

Journal: The Annals of thoracic surgery 20041201

Title: Effect of bivalirudin on length of stay in the recovery area after percutaneous coronary intervention compared with heparin alone, heparin + abciximab, or heparin + eptifibatide.

Journal: The American journal of cardiology 20041201

Title: Drugs for percutaneous coronary interventions.

Journal: The Medical letter on drugs and therapeutics 20041201

Title: Current role of antithrombotic agents in the treatment of acute coronary syndromes.

Journal: Seminars in thrombosis and hemostasis 20041201

Title: Anticoagulant monitoring techniques in a heparin-induced thrombocytopenia patient undergoing cardiopulmonary bypass using bivalirudin anticoagulant.

Journal: The journal of extra-corporeal technology 20041201

Title: Economic evaluation of bivalirudin with provisional glycoprotein IIB/IIIA inhibition versus heparin with routine glycoprotein IIB/IIIA inhibition for percutaneous coronary intervention: results from the REPLACE-2 trial.

Journal: Journal of the American College of Cardiology 20041102

Title: Economic impact of new interventional therapies: are we asking the right questions?

Journal: Journal of the American College of Cardiology 20041102

Title: Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial: study design and rationale.

Journal: American heart journal 20041101

Title: The Angiomax Peripheral Procedure Registry of Vascular Events Trial (APPROVE): in-hospital and 30-day results.

Journal: The Journal of invasive cardiology 20041101

Title: Bivalirudin versus heparin as an antithrombotic agent in patients treated with a sirolimus-eluting stent.

Journal: The American journal of cardiology 20041015

Title: Novel antithrombotic agents: indirect synthetic inhibitors of factor Xa and direct thrombin inhibitors. Evidences from clinical studies.

Journal: Current medicinal chemistry. Cardiovascular and hematological agents 20041001

Title: Effects of pentasaccharide (fondaparinux) and direct thrombin inhibitors on coagulation testing.

Journal: Archives of pathology & laboratory medicine 20041001

Title: Lack of clopidogrel pretreatment effect on the relative efficacy of bivalirudin with provisional glycoprotein IIb/IIIa blockade compared to heparin with routine glycoprotein IIb/IIIa blockade: a REPLACE-2 substudy.

Journal: Journal of the American College of Cardiology 20040915

Title: Value of monitoring activated clotting time when bivalirudin is used as the sole anticoagulation agent for percutaneous coronary intervention.

Journal: The American journal of cardiology 20040915

Title: Comparing direct thrombin inhibitors using aPTT, ecarin clotting times, and thrombin inhibitor management testing.

Journal: The Annals of pharmacotherapy 20040901

Title: Use of bivalirudin instead of heparin during a percutaneous coronary intervention in a patient with severe thrombocytopenia.

Journal: The Journal of invasive cardiology 20040901

Title: Anticoagulation with bivalirudin during percutaneous coronary intervention for ST-segment elevation myocardial infarction.

Journal: The Journal of invasive cardiology 20040901

Title: Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

Journal: Chest 20040901

Title: Antithrombotic therapy during percutaneous coronary intervention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

Journal: Chest 20040901

Title: Visual compatibility of bivalirudin with selected drugs.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040901

Title: Relationship between activated clotting time and ischemic or hemorrhagic complications: analysis of 4 recent randomized clinical trials of percutaneous coronary intervention.

Journal: Circulation 20040824

Title: Long-term efficacy of bivalirudin and provisional glycoprotein IIb/IIIa blockade vs heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary revascularization: REPLACE-2 randomized trial.

Journal: JAMA 20040811

Title: An overview of antithrombins in peripheral vascular interventions.

Journal: The Journal of invasive cardiology 20040801

Title: Unfractionated heparin in cardiology: redefining the standard of practice.

Journal: Pharmacotherapy 20040801

Title: Current and future antithrombotic agents in children.

Journal: Expert review of cardiovascular therapy 20040701

Title: Direct antithrombins: new perspectives in cardiovascular medicine.

Journal: Current medicinal chemistry. Cardiovascular and hematological agents 20040701

Title: Reversal of direct thrombin inhibition after cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia.

Journal: Anesthesia and analgesia 20040601

Title: Successful multi-vessel percutaneous coronary intervention with bivalirudin in a patient with severe hemophilia A: a case report and review of literature.

Journal: The Journal of invasive cardiology 20040601

Title: Bivalirudin-associated intracoronary thrombosis during gamma-brachytherapy and its experimental validation in acute swine model.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040601

Title: Percutaneous interventions in patients with immune-mediated heparin-induced thrombocytopenia.

Journal: Seminars in thrombosis and hemostasis 20040601

Title: The use of direct thrombin inhibitors in cardiovascular surgery in patients with heparin-induced thrombocytopenia.

Journal: Seminars in thrombosis and hemostasis 20040601

Title: Bivalirudin in PCI: an overview of the REPLACE-2 trial.

Journal: Seminars in thrombosis and hemostasis 20040601

Title: Bivalirudin, blood loss, and graft patency in coronary artery bypass surgery.

Journal: Seminars in thrombosis and hemostasis 20040601

Title: Plasma-modified ACT can be used to monitor bivalirudin (Angiomax) anticoagulation for on-pump cardiopulmonary bypass surgery in a patient with heparin-induced thrombocytopenia.

Journal: The journal of extra-corporeal technology 20040601

Title: Validation of the i-STAT handheld activated clotting time for use with bivalirudin.

Journal: The American journal of cardiology 20040515

Title: Resolution of intracoronary thrombus with direct thrombin inhibition in a cocaine abuser.

Journal: Heart (British Cardiac Society) 20040501

Title: Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to Reduced Clinical Events [REPLACE]-1 trial).

Journal: The American journal of cardiology 20040501

Title: The use of bivalirudin to prevent subacute thrombosis during drug-eluting stent implantation.

Journal: The Journal of invasive cardiology 20040501

Title: New anticoagulation.

Journal: The Journal of invasive cardiology 20040501

Title: Novel uses for current and future direct thrombin inhibitors: focus on ximelagatran and bivalirudin.

Journal: Expert opinion on investigational drugs 20040501

Title: Liquid chromatography method for determination of bivalirudin in human plasma and urine using automated ortho-phthalaldehyde derivatization and fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040405

Title: Effect of direct thrombin inhibitors, bivalirudin, lepirudin, and argatroban, on prothrombin time and INR values.

Journal: American journal of clinical pathology 20040401

Title: Bivalirudin versus heparin and protamine in off-pump coronary artery bypass surgery.

Journal: The Annals of thoracic surgery 20040301

Title: Bivalirudin: an anticoagulant option for percutaneous coronary intervention.

Journal: Expert review of cardiovascular therapy 20040301

Title: Bivalent direct thrombin inhibitors: hirudin and bivalirudin.

Journal: Best practice & research. Clinical haematology 20040301

Title: Selective use of bivalirudin to reduce post-PCI vascular complications.

Journal: Critical pathways in cardiology 20040301

Title: Effectiveness of bivalirudin as a replacement for heparin during cardiopulmonary bypass in patients undergoing coronary artery bypass grafting.

Journal: The American journal of cardiology 20040201

Title: Antibodies against lepirudin are polyspecific and recognize epitopes on bivalirudin.

Journal: Blood 20040115

Title: Bivalirudin for endovascular intervention in acute ischemic stroke: case report.

Journal: Neurosurgery 20040101

Title: Benefits of direct angioplasty for women and men with acute myocardial infarction: results of the Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes Angioplasty (GUSTO II-B) Angioplasty Substudy.

Journal: American heart journal 20040101

Title: Direct thrombin inhibitors for anticoagulation.

Journal: The Annals of pharmacotherapy 20040101

Title: Adjunctive use of direct thrombin inhibitors in patients receiving fibrinolytic therapy for acute myocardial infarction.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101

Title: Point-of-care ecarin clotting time versus activated clotting time in correlation with bivalirudin concentration.

Journal: Thrombosis research 20040101

Title: Addition of heparin to contrast media is associated with increased bleeding and peripheral vascular complications during percutaneous coronary intervention with bivalirudin and drug-eluting stents.

Journal: Cardiovascular radiation medicine 20040101

Title: [Oral antithrombins and the future of antithrombotic therapy].

Journal: Revista espanola de cardiologia 20040101

Title: Clinical potential of oral direct thrombin inhibitors in the prevention and treatment of venous thromboembolism.

Journal: Drugs 20040101

Title: Update on acute coronary syndromes and implications for therapy.

Journal: Expert opinion on investigational drugs 20031201

Title: Heparin-induced thrombocytopenia and cardiac surgery.

Journal: The Annals of thoracic surgery 20031201

Title: Bivalirudin as alternative to both danaparoid and heparin in off-pump coronary artery bypass grafting.

Journal: The Journal of thoracic and cardiovascular surgery 20031201

Title: Bivalirudin alone in the treatment of acute myocardial infarction.

Journal: The Journal of invasive cardiology 20031201

Title: Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.

Journal: Circulation 20031125

Title: Comparison of effectiveness and safety of three different antithrombotic regimens (bivalirudin, eptifibatide, and heparin) in preventing myocardial ischemia during percutaneous coronary intervention.

Journal: The American journal of cardiology 20031101

Title: The anticoagulant therapy with bivalirudin to assist in the performance of percutaneous coronary intervention in patients with heparin-induced thrombocytopenia (ATBAT) study: main results.

Journal: The Journal of invasive cardiology 20031101

Title: Advances in antithrombin therapy for ST-elevation myocardial infarction.

Journal: Chinese medical journal 20031101

Title: Bivalirudin provides increasing benefit with decreasing renal function: a meta-analysis of randomized trials.

Journal: The American journal of cardiology 20031015

Title: Direct thrombin inhibitor therapy in the cardiovascular patient.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20031015

Title: Argatroban for off-pump coronary artery bypass surgery.

Journal: Anesthesia and analgesia 20031001

Title: Direct thrombin inhibitors for non-ST-segment elevation acute coronary syndromes: what, when, and where?

Journal: American heart journal 20031001

Title: Successful use of bivalirudin for cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia.

Journal: Journal of cardiothoracic and vascular anesthesia 20031001

Title: Bivalirudin in percutaneous coronary intervention.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030915

Title: Peptidomimetic thrombin inhibitors.

Journal: Pathophysiology of haemostasis and thrombosis 20030901

Title: Can bivalirudin and provisional GP IIb/IIIa blockade REPLACE heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention?

Journal: Expert opinion on pharmacotherapy 20030801

Title: Contemporary use of antiplatelet therapies in percutaneous coronary interventions.

Journal: Coronary artery disease 20030801

Title: Heparin-induced thrombocytopenia and cardiac surgery.

Journal: The Annals of thoracic surgery 20030801

Title: Current anticoagulant therapy--unmet clinical needs.

Journal: Thrombosis research 20030715

Title: Economic impact of bleeding complications and the role of antithrombotic therapies in percutaneous coronary intervention.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030715

Title: Bivalirudin in peripheral vascular interventions: a single center experience.

Journal: The Journal of invasive cardiology 20030701

Title: Bivalirudin use in off-pump myocardial revascularization in patients with heparin-induced thrombocytopenia [corrected].

Journal: The Annals of thoracic surgery 20030701

Title: Hirulog-like peptide reduces restenosis and expression of tissue factor and transforming growth factor-beta in carotid artery of atherosclerotic rabbits.

Journal: Atherosclerosis 20030701

Title: Bivalirudin as a foundation anticoagulant in peripheral vascular disease: a safe and feasible alternative for renal and iliac interventions.

Journal: The Journal of invasive cardiology 20030601

Title: Evolving role of bivalirudin in percutaneous coronary interventions; impact of the REPLACE-2 study.

Journal: Expert opinion on investigational drugs 20030601

Title: An assessment of different filter systems for extracorporeal elimination of bivalirudin: an in vitro study.

Journal: Anesthesia and analgesia 20030501

Title: Correlation of point-of-care ecarin clotting time versus activated clotting time with bivalirudin concentrations.

Journal: The American journal of cardiology 20030501

Title: In-hospital complications of peripheral vascular interventions using unfractionated heparin as the primary anticoagulant.

Journal: The Journal of invasive cardiology 20030501

Title: Direct thrombin inhibitors.

Journal: Expert opinion on pharmacotherapy 20030501

Title: Predicting the pharmacology of thrombin inhibitors.

Journal: Journal of thrombosis and haemostasis : JTH 20030501

Title: Anticoagulation in acute cardiac care in patients with chronic kidney disease.

Journal: American heart journal 20030401

Title: Management of thrombotic and cardiovascular disorders in the new millenium.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20030401

Title: Safe and efficacious use of bivalirudin for percutaneous coronary intervention with adjunctive platelet glycoprotein IIb/IIIa receptor inhibition.

Journal: The American journal of cardiology 20030315

Title: Informed consent during the clinical emergency of acute myocardial infarction (HERO-2 consent substudy): a prospective observational study.

Journal: Lancet (London, England) 20030315

Title: Bivalirudin (Angiomax) use during intracoronary brachytherapy may predispose to acute closure.

Journal: Journal of cardiovascular pharmacology and therapeutics 20030301

Title: Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial.

Journal: JAMA 20030219

Title: Should bivalirudin replace heparin during percutaneous coronary interventions?

Journal: JAMA 20030219

Title: The evolving role of direct thrombin inhibitors in acute coronary syndromes.

Journal: Journal of the American College of Cardiology 20030219

Title: Bivalirudin monitored with the ecarin clotting time for anticoagulation during cardiopulmonary bypass.

Journal: Anesthesia and analgesia 20030201

Title: Clinician update: direct thrombin inhibitors in acute coronary syndromes.

Journal: Journal of thrombosis and thrombolysis 20030201

Title: Alternative methods of anticoagulation for dialysis-dependent patients with heparin-induced thrombocytopenia.

Journal: Seminars in dialysis 20030101

Title: Favorable outcome with bivalirudin anticoagulation during cardiopulmonary bypass.

Journal: The Annals of thoracic surgery 20030101

Title: Direct thrombin inhibitors in cardiac disease.

Journal: Cardiovascular toxicology 20030101

Title: A 24-hour continuous infusion study of bivalirudin in the rat.

Journal: International journal of toxicology 20030101

Title: Effect of non-heparin thrombin antagonists on thrombin generation, platelet function, and clot structure in whole blood.

Journal: Cell biochemistry and biophysics 20030101

Title: New anticoagulants: current status and future potential.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

Title: Anticoagulation with bivalirudin during cardiopulmonary bypass in cardiac surgery.

Journal: The Annals of thoracic surgery 20021201

Title: A Bayesian ordinal model for heterogeneity in a multi-centre myocardial infarction clinical trial.

Journal: Statistics in medicine 20021030

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20021001

Title: Slowed ST segment recovery despite early infarct artery patency in patients with Q waves at presentation with a first acute myocardial infarction. Implications of initial Q waves on myocyte reperfusion.

Journal: European heart journal 20020901

Title: Direct thrombin inhibitors in acute coronary syndromes.

Journal: Lancet (London, England) 20020810

Title: Bivalirudin: a direct thrombin inhibitor for percutaneous transluminal coronary angioplasty.

Journal: Pharmacotherapy 20020801

Title: Bivalirudin, a bivalent, thrombin specific anticoagulant as an alternative to heparin in interventional procedures as an alternative to heparin in interventional procedures.

Journal: Hamostaseologie 20020801

Title: Direct thrombin inhibitors.

Journal: Seminars in hematology 20020701

Title: Pharmacology and clinical use of bivalirudin.

Journal: The Annals of pharmacotherapy 20020601

Title: Bivalirudin: an anticoagulant for acute coronary syndromes and coronary interventions.

Journal: Expert opinion on pharmacotherapy 20020601

Title: Absolute and relative truth in clinical trials.

Journal: Lancet (London, England) 20020601

Title: Clinical pharmacology of bivalirudin.

Journal: Pharmacotherapy 20020601

Title: Bivalirudin administration during percutaneous coronary intervention: emphasis on high-risk patients.

Journal: Pharmacotherapy 20020601

Title: A practical cost analysis of bivalirudin.

Journal: Pharmacotherapy 20020601

Title: The role of thrombin inhibition during percutaneous coronary intervention.

Journal: Pharmacotherapy 20020601

Title: Selective inhibition of coagulation factors: advances in antithrombotic therapy.

Journal: Seminars in thrombosis and hemostasis 20020601

Title: Bivalirudin pharmacokinetics and pharmacodynamics: effect of renal function, dose, and gender.

Journal: Clinical pharmacology and therapeutics 20020601

Title: Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: implications for coronary intervention.

Journal: Journal of thrombosis and thrombolysis 20020601

Title: Heparin, bivalirudin, and reduction of complications during percutaneous coronary intervention.

Journal: Pharmacotherapy 20020601

Title: Bivalirudin with planned or provisional abciximab versus low-dose heparin and abciximab during percutaneous coronary revascularization: results of the Comparison of Abciximab Complications with Hirulog for Ischemic Events Trial (CACHET).

Journal: American heart journal 20020501

Title: Direct thrombin inhibitors.

Journal: Thrombosis research 20020501

Title: Pharmacodynamic profile of the direct thrombin antagonist bivalirudin given in combination with the glycoprotein IIb/IIIa antagonist eptifibatide.

Journal: American heart journal 20020401

Title: Building a stronger foundation: improved antithrombin therapy with bivalirudin in percutaneous coronary intervention.

Journal: The Journal of invasive cardiology 20020401

Title: Overcoming heparin limitations in high-risk percutaneous coronary intervention: the alternative strategy-- replacing heparin with bivalirudin.

Journal: The Journal of invasive cardiology 20020401

Title: New drugs 2002. Part II.

Journal: Nursing 20020401

Title: Direct thrombin inhibitors for percutaneous coronary intervention in the current era of platelet glycoprotein IIb/IIIa inhibition.

Journal: Journal of interventional cardiology 20020401

Title: Percutaneous coronary intervention with bivalirudin anticoagulation, immediate sheath removal, and early ambulation: a feasibility study with implications for day-stay procedures.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020301

Title: Publication policy, informed consent, and the randomized clinical trial.

Journal: American heart journal 20020201

Title: Improved efficacy and less bleeding: further evidence of a unique uncoupling of benefit and risk with bivalirudin.

Journal: American heart journal 20020201

Title: Bivalirudin as a replacement for unfractionated heparin in unstable angina/non-ST-elevation myocardial infarction: observations from the TIMI 8 trial. The Thrombolysis in Myocardial Infarction.

Journal: American heart journal 20020201

Title: Direct thrombin inhibitors in acute coronary syndromes: principal results of a meta-analysis based on individual patients' data.

Journal: Lancet (London, England) 20020126

Title: Bivalirudin: a direct thrombin inhibitor.

Journal: Clinical therapeutics 20020101

Title: Bivalirudin: a review of its potential place in the management of acute coronary syndromes.

Journal: Drugs 20020101

Title: [What is new in antithrombotic treatment?].

Journal: Annales de biologie clinique 20020101

Title: Management of patients with acute coronary syndromes: what is the clinical role of direct thrombin inhibitors?

Journal: Drugs 20020101

Title: Optimal treatment and current situation in reperfusion after thrombolysis for acute myocardial infarction.

Journal: Annals of medicine 20020101

Title: Current anticoagulation options in percutaneous intervention: designing patient-specific strategies.

Journal: Reviews in cardiovascular medicine 20020101

Title: Reversing anticoagulants both old and new.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20020101

Title: Current developments in antithrombotic therapy: the role of antithrombin agents.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: Heparin-induced thrombocytopenia: pathophysiology and new treatment options.

Journal: Pathophysiology of haemostasis and thrombosis 20020101

Title: A second look at bivalirudin.

Journal: American heart journal 20011201

Title: Bivalirudin versus heparin during coronary angioplasty for unstable or postinfarction angina: Final report reanalysis of the Bivalirudin Angioplasty Study.

Journal: American heart journal 20011201

Title: Thrombin-specific anticoagulation with bivalirudin versus heparin in patients receiving fibrinolytic therapy for acute myocardial infarction: the HERO-2 randomised trial.

Journal: Lancet (London, England) 20011201

Title: Pharmacologic preservation of the hemostatic system during cardiac surgery.

Journal: The Annals of thoracic surgery 20011101

Title: [Fibrinolysis in myocardial infarction with EKG elevation. Optimization of myocardial reperfusion by treatment with antithrombotic agents].

Journal: Archives des maladies du coeur et des vaisseaux 20011101

Title: Caspofungin acetate, bivalirudin.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20011001

Title: Bivalirudin for percutaneous coronary intervention and in acute coronary syndromes.

Journal: Current cardiology reports 20010901

Title: New anticoagulants.

Journal: American heart journal 20010801

Title: Direct thrombin inhibitors: are they the future of anticoagulation?

Journal: South Dakota journal of medicine 20010601

Title: Development and current applications of thrombin-specific inhibitors.

Journal: Current drug targets. Cardiovascular & haematological disorders 20010601

Title: Advances in the development of thrombin inhibitors.

Journal: Expert opinion on investigational drugs 20010501

Title: Laser-induced noninvasive vascular injury models in mice generate platelet- and coagulation-dependent thrombi.

Journal: The American journal of pathology 20010501

Title: Bivalirudin (Angiomax) for angioplasty.

Journal: The Medical letter on drugs and therapeutics 20010430

Title: [Direct thrombin antagonists].

Journal: Herz 20010401

Title: Thrombin inhibitor approved for anticoagulation during angioplasty.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010301

Title: From the Food and Drug Administration.

Journal: JAMA 20010214

Title: Direct and indirect antithrombins. Heparins, low molecular weight heparins, heparinoids, and hirudin.

Journal: Clinics in geriatric medicine 20010201

Title: Ecarin clotting time is sensitive to heparinoids: comparison of two different techniques.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20010101

Title: Hirulog-like peptide reduces balloon catheter injury induced neointima formation in rat carotid artery without increase in bleeding tendency.

Journal: Journal of vascular research 20010101

Title: Bivalirudin: a new approach to anticoagulation.

Journal: Heart disease (Hagerstown, Md.) 20010101

Title: The use of bivalirudin in patients with renal impairment.

Journal: The Journal of invasive cardiology 20001201

Title: Hirulog-1 reduces expression of platelet-derived growth factor in neointima of rat carotid artery induced by balloon catheter injury.

Journal: Journal of vascular research 20000101

Title: Direct thrombin inhibitors.

Journal: Haemostasis 19991201

Title: Clinical outcomes of bivalirudin for ischemic heart disease.

Journal: Circulation 19991116

Title: Effective use of BCH-2763, a new potent injectable direct thrombin inhibitor, in combination with tissue plasminogen activator (tPA) in a rat arterial thrombolysis model.

Journal: Thrombosis and haemostasis 19980701

Title: Transcellular signaling and pharmacological modulation of thrombin-induced production of plasminogen activator inhibitor-1 in vascular smooth muscle cells.

Journal: Seminars in thrombosis and hemostasis 19980101

Title: Inhibition by hirulog-1 of generation of plasminogen activator inhibitor-1 from vascular smooth-muscle cells induced by thrombin.

Journal: Journal of cardiovascular pharmacology 19970301

Title: Anticoagulant activity of Hirulog, a direct thrombin inhibitor, in humans.

Journal: Thrombosis and haemostasis 19930201

Title: Thrombin-specific inhibition by and slow cleavage of hirulog-1.

Journal: The Biochemical journal 19920501

Title: Bates ER, et al. Bivalirudin: an anticoagulant option for percutaneous coronary intervention.Expert Rev Cardiovasc Ther. 2004 Mar;2(2):153-62.

Title: André P, et al. Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.Circulation. 2003 Nov 25;108(21):2697-703.

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Tags:128270-60-0 Molecular Formula|128270-60-0 MDL|128270-60-0 SMILES|128270-60-0 Bivalirudin