Home Amines 189290-58-2
189290-58-2,MFCD28902185
Catalog No.:AA00AQW1

189290-58-2 | 4-Quinazolinamine, n-(3-iodophenyl)-6,7-dimethoxy-

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5mg
≥95%
in stock  
$105.00   $73.00
- +
10mg
≥95%
in stock  
$198.00   $138.00
- +
25mg
98%
in stock  
$349.00   $244.00
- +
50mg
98%
in stock  
$543.00   $380.00
- +
100mg
98%
in stock  
$834.00   $584.00
- +
500mg
98% by HPLC
in stock  
$2,920.00   $2,044.00
- +
1000mg
98% by HPLC
in stock  
$4,634.00   $3,244.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AQW1
Chemical Name:
4-Quinazolinamine, n-(3-iodophenyl)-6,7-dimethoxy-
CAS Number:
189290-58-2
Molecular Formula:
C16H14IN3O2
Molecular Weight:
407.2057
MDL Number:
MFCD28902185
SMILES:
COc1cc2c(ncnc2cc1OC)Nc1cccc(c1)I
Properties
Computed Properties
 
Complexity:
360  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
4  

Literature

Title: Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor.

Journal: Journal of medicinal chemistry 19960105

Title: Akshada Joshi, et al. Identification of Potential Novel EGFR Inhibitors using a Combination of Pharmacophore and Docking Methods. International Journal of Pharmacy and Pharmaceutical Sciences, ISSN- 0975-1491 Vol 7, Issue 6, 2015

Title: Ellis AG, et al. High-performance liquid chromatographic analysis of the tyrphostin AG1478, a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in mouse plasma. J Chromatogr B Biomed Sci Appl. 2001 Apr 15;754(1):193-9.

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SDS
Tags:189290-58-2 Molecular Formula|189290-58-2 MDL|189290-58-2 SMILES|189290-58-2 4-Quinazolinamine, n-(3-iodophenyl)-6,7-dimethoxy-