Title: Tighter control of postprandial hyperglycemia with mitiglinide/voglibose fixed-dose combination in Japanese patients with type 2 diabetes mellitus.
Journal: Expert opinion on pharmacotherapy 20121101
Title: Hollow fiber liquid-phase microextraction combined with high performance liquid chromatography for the determination of trace mitiglinide in biological fluids.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120501
Title: Comparison of the rapidity of onset of the therapeutic effect between nateglinide and mitiglinide by PK/PD analysis in rats.
Journal: European journal of drug metabolism and pharmacokinetics 20120301
Title: Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A.
Journal: Pharmacogenetics and genomics 20120301
Title: The effects of food on the pharmacokinetics of mitiglinide tablets in healthy volunteers and a novel mass-spectrometric (UPLC-MS/MS) method for such studies.
Journal: Journal of clinical pharmacy and therapeutics 20120201
Title: Efficacy and safety of mitiglinide versus nateglinide in newly diagnose patients with type 2 diabetes mellitus: a randomized double blind trial.
Journal: Diabetes, obesity & metabolism 20120201
Title: Variations in tissue selectivity amongst insulin secretagogues: a systematic review.
Journal: Diabetes, obesity & metabolism 20120201
Title: Mitiglinide treatment may decreases plasma fibroblast growth factor-21 levels in individuals with new-onset T2DM.
Journal: Cytokine 20120201
Title: Effect of gemfibrozil on the pharmacokinetics of mitiglinide in rats.
Journal: Arzneimittel-Forschung 20120101
Title: Mitiglinide: a novel agent for the treatment of type 2 diabetes mellitus.
Journal: The Annals of pharmacotherapy 20101001
Title: Combination therapy with mitiglinide and voglibose improves glycemic control in type 2 diabetic patients on hemodialysis.
Journal: Expert opinion on pharmacotherapy 20100201
Title: Efficacy and safety of mitiglinide in diabetic patients on maintenance hemodialysis.
Journal: Endocrine journal 20100101
Title: Effect of mitiglinide on Streptozotocin-induced experimental type 2 diabetic rats: a urinary metabonomics study based on ultra-performance liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101
Title: Treatment with glimepiride, but not mitiglinide and short-acting insulin, resists body weight and abdominal fat reduction under dietary energy restriction.
Journal: Journal of atherosclerosis and thrombosis 20090301
Title: Addition of mitiglinide to pioglitazone monotherapy improves overall glycemic control in Japanese patients with type 2 diabetes: a randomized double blind trial.
Journal: Endocrine journal 20090101
Title: Effect of mitiglinide on glycemic control over 52 weeks in Japanese type 2 diabetic patients insufficiently controlled with pioglitazone monotherapy.
Journal: Endocrine journal 20090101
Title: Multicentre, double-blind, randomized study of mitiglinide compared with nateglinide in type 2 diabetes mellitus patients in China.
Journal: The Journal of international medical research 20090101
Title: Pleiotropic effects of mitiglinide in type 2 diabetes mellitus.
Journal: The Journal of international medical research 20090101
Title: Mitiglinide: a rapid- and short-acting non-sulfonylurea insulinotropic agent for the treatment of type 2 diabetic patients.
Journal: Expert opinion on pharmacotherapy 20081001
Title: Liquid chromatography/electrospray ionization tandem mass spectrometry for the quantification of mitiglinide in human plasma: validation and its application to pharmacokinetic studies.
Journal: Biomedical chromatography : BMC 20080801
Title: Quantitative determination of mitiglinide in human plasma by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080601
Title: Nateglinide and mitiglinide, but not sulfonylureas, induce insulin secretion through a mechanism mediated by calcium release from endoplasmic reticulum.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases.
Journal: Biochemical pharmacology 20070601
Title: Mitiglinide, a novel oral hypoglycemic agent, preserves the cardioprotective effect of ischemic preconditioning in isolated perfused rat hearts.
Journal: International heart journal 20070501
Title: High-performance liquid chromatography-electrospray ionization mass spectrometry determination of mitiglinide in human plasma and its pharmacokinetics.
Journal: Journal of mass spectrometry : JMS 20070201
Title: Long-term effect of combination therapy with mitiglinide and once daily insulin glargine in patients who were successfully switched from intensive insulin therapy in short-term study.
Journal: Endocrine journal 20070201
Title: Effect of combination therapy of a rapid-acting insulin secretagogue (glinide) with premixed insulin in type 2 diabetes mellitus.
Journal: Internal medicine (Tokyo, Japan) 20070101
Title: [Glinide(s), sulfonylurea(s)].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20061101
Title: Imaging docking and fusion of insulin granules induced by antidiabetes agents: sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules.
Journal: Diabetes 20061001
Title: Determination of mitiglinide in rat plasma by high-performance liquid chromatography with UV detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060413
Title: Effects of mitiglinide on glucose-induced insulin release into the portal vein and fat-induced triglyceride elevation in prediabetic and diabetic OLETF rats.
Journal: Endocrine 20060401
Title: Effects of mitiglinide and sulfonylureas in isolated canine coronary arteries and perfused rat hearts.
Journal: European journal of pharmacology 20060215
Title: Therapeutic efficacy of mitiglinide combined with once daily insulin glargine after switching from multiple daily insulin regimen of aspart insulin and glargine in patients with type 2 diabetes mellitus.
Journal: Endocrine journal 20060201
Title: [Significance of insulin secretion pattern lectured by 'glinides' in the treatment of postprandial hyperglycemia].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20051201
Title: [Synthesis and insulinotropic activity of 2-benzylidenesuccinic acid derivatives].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051201
Title: Characterization of the action of S 21403 (mitiglinide) on insulin secretion and biosynthesis in normal and diabetic beta-cells.
Journal: British journal of pharmacology 20051101
Title: Effects of S21403 (mitiglinide) on postprandial generation of oxidative stress and inflammation in type 2 diabetic patients.
Journal: Diabetologia 20050901
Title: [Selection of oral antidiabetic drugs].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201
Title: [Effects of mitiglinide in treatment of impaired glucose tolerance].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201
Title: [Pharmacological and clinical profile of mitiglinide calcium hydrate (Glufast), a new insulinotropic agent with rapid onset].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20041001
Title: [Achieving better control of blood sugar--understanding of oral hypoglycemic agents according to their characteristics in pharmacological action mechanism (discussion)].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20040401
Title: Mitiglinide: KAD 1229, S 21403.
Journal: Drugs in R&D 20040101
Title: [Nateglinide and mitiglinide].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20030701
Title: Effects of S 21403 on hormone secretion from isolated rat pancreas at different glucose concentrations.
Journal: European journal of pharmacology 20021205
Title: [Structures and mechanisms for non SU insulin secretagogues].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901
Title: [Mitiglinide (KAD-1229)].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901
Title: Effect of KAD-1229, a novel hypoglycaemic agent, on plasma glucose levels after meal load in type 2 diabetic rats.
Journal: Clinical and experimental pharmacology & physiology 20020101
Title: Study of the insulinotropic effect of the novel antihyperglycemic agent KAD-1229 using HIT T15 cells, a hamster's insulinoma cell line.
Journal: Arzneimittel-Forschung 20020101
Title: Absence of exacerbation of myocardial stunning in anesthetized dogs treated with KAD-1229, a novel hypoglycemic agent.
Journal: European journal of pharmacology 20011123
Title: The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide.
Journal: European journal of pharmacology 20011109
Title: Rapid acting insulinotropic agents: restoration of early insulin secretion as a physiologic approach to improve glucose control.
Journal: Current pharmaceutical design 20010901
Title: Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel.
Journal: British journal of pharmacology 20010401
Title: Effect of KAD-1229, a nonsulfonylurea hypoglycemic agent, on plasma glucose and insulin in streptozotocin-induced diabetic dogs.
Journal: Pharmacology 20010201
Title: Y Sunaga, et al. The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide. Eur J Pharmacol. 2001 Nov 9;431(1):119-25.
Title: Kiyoshi Ichikawa, et al. Effect of KAD-1229, a novel hypoglycaemic agent, on plasma glucose levels after meal load in type 2 diabetic rats. Clin Exp Pharmacol Physiol. May-Jun 2002;29(5-6):423-7.
