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2207-75-2,MFCD00010565
Catalog No.:AA003TU6

2207-75-2 | potassium 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylate

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250mg
98%
in stock  
$6.00   $4.00
- +
1g
95%
in stock  
$10.00   $7.00
- +
5g
98%
in stock  
$16.00   $11.00
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10g
98%
in stock  
$22.00   $15.00
- +
25g
95%
in stock  
$38.00   $26.00
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100g
98%
in stock  
$117.00   $82.00
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500g
98%
in stock  
$520.00   $364.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003TU6
Chemical Name:
potassium 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylate
CAS Number:
2207-75-2
Molecular Formula:
C4H2KN3O4
Molecular Weight:
195.1747
MDL Number:
MFCD00010565
SMILES:
O=c1[nH]c(=O)[nH]c(n1)C(=O)[O-].[K+]
Properties
Properties
 
Form:
Solid  
MP:
300 °C(lit.)  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
274  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  

Literature

Title: Hypouricemic effect of the methanol extract from Prunus mume fruit in mice.

Journal: Pharmaceutical biology 20121101

Title: Uricosuric and nephroprotective properties of Ramulus Mori ethanol extract in hyperuricemic mice.

Journal: Journal of ethnopharmacology 20121011

Title: Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.

Journal: Molecular nutrition & food research 20120901

Title: Reducing effect of mangiferin on serum uric acid levels in mice.

Journal: Pharmaceutical biology 20120901

Title: Quercetin regulates organic ion transporter and uromodulin expression and improves renal function in hyperuricemic mice.

Journal: European journal of nutrition 20120801

Title: Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis: anti-hyperuricemic and anti-inflammatory effects of its extract, fraction and constituents.

Journal: Journal of ethnopharmacology 20120801

Title: Anti-hyperuricemic and nephroprotective effects of Modified Simiao Decoction in hyperuricemic mice.

Journal: Journal of ethnopharmacology 20120626

Title: Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits.

Journal: Bioorganic & medicinal chemistry 20120501

Title: Protective effects of cortex fraxini coumarines against oxonate-induced hyperuricemia and renal dysfunction in mice.

Journal: European journal of pharmacology 20110901

Title: Clinical results of definitive chemoradiotherapy for patients with synchronous head and neck squamous cell carcinoma and esophageal cancer.

Journal: American journal of clinical oncology 20110801

Title: The therapeutic efficacy of S-1 against orthotopically implanted human pleural mesothelioma cells in severe combined immunodeficient mice.

Journal: Cancer chemotherapy and pharmacology 20110801

Title: [Efficacy and side effects of combination therapy of oxaliplatin and S-1 for colorectal cancer].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110501

Title: 3,5,2',4'-Tetrahydroxychalcone, a new non-purine xanthine oxidase inhibitor.

Journal: Chemico-biological interactions 20110201

Title: Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.

Journal: European journal of pharmacology 20101215

Title: [Mangiferin promotes uric acid excretion and kidney function improvement and modulates related renal transporters in hyperuricemic mice].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20101001

Title: Phytochemicals from Acacia confusa heartwood extracts reduce serum uric acid levels in oxonate-induced mice: their potential use as xanthine oxidase inhibitors.

Journal: Journal of agricultural and food chemistry 20100922

Title: Simiao pill ameliorates urate underexcretion and renal dysfunction in hyperuricemic mice.

Journal: Journal of ethnopharmacology 20100421

Title: Pharmacokinetic study of S-1.

Journal: International journal of clinical pharmacology and therapeutics 20090101

Title: Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats.

Journal: Chemico-biological interactions 20081125

Title: Essential oil from leaves of Cinnamomum osmophloeum acts as a xanthine oxidase inhibitor and reduces the serum uric acid levels in oxonate-induced mice.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20081101

Title: [Curative effects of FTQ combined with cisplatin in treatment of advanced gastric cancer: a multicenter study].

Journal: Zhonghua yi xue za zhi 20080527

Title: Flavonoids of Cynara scolymus possess potent xanthinoxidase inhibitory activity in vitro but are devoid of hypouricemic effects in rats after oral application.

Journal: Planta medica 20080201

Title: Hypouricemic effects of phenylpropanoid glycosides acteoside of Scrophularia ningpoensis on serum uric acid levels in potassium oxonate-pretreated Mice.

Journal: The American journal of Chinese medicine 20080101

Title: Hypouricemic action of selected flavonoids in mice: structure-activity relationships.

Journal: Biological & pharmaceutical bulletin 20070801

Title: Xanthine oxidase inhibitory activity of some Indian medical plants.

Journal: Journal of ethnopharmacology 20070212

Title: The endogenous danger signal uric Acid augments contact hypersensitivity responses in mice.

Journal: Pathobiology : journal of immunopathology, molecular and cellular biology 20070101

Title: Potassium oxonate, an enzyme inhibitor compounded in S-1, reduces the suppression of antitumor immunity induced by 5-fluorouracil.

Journal: Cancer chemotherapy and pharmacology 20060801

Title: Effects of cassia oil on serum and hepatic uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver.

Journal: Journal of ethnopharmacology 20060220

Title: The dual actions of morin (3,5,7,2',4'-pentahydroxyflavone) as a hypouricemic agent: uricosuric effect and xanthine oxidase inhibitory activity.

Journal: The Journal of pharmacology and experimental therapeutics 20060101

Title: Effect and mechanism of total saponin of Dioscorea on animal experimental hyperuricemia.

Journal: The American journal of Chinese medicine 20060101

Title: Hypouricemic effects of acacetin and 4,5-o-dicaffeoylquinic acid methyl ester on serum uric acid levels in potassium oxonate-pretreated rats.

Journal: Biological & pharmaceutical bulletin 20051201

Title: Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts.

Journal: Oncology reports 20050701

Title: Effects of Biota orientalis extract and its flavonoid constituents, quercetin and rutin on serum uric acid levels in oxonate-induced mice and xanthine dehydrogenase and xanthine oxidase activities in mouse liver.

Journal: Journal of ethnopharmacology 20040701

Title: Administration of procyanidins from grape seeds reduces serum uric acid levels and decreases hepatic xanthine dehydrogenase/oxidase activities in oxonate-treated mice.

Journal: Basic & clinical pharmacology & toxicology 20040501

Title: Increased intestinal permeability correlates with gastrointestinal toxicity among formulations of the fluorouracil analogue tegafur in rats.

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20020101

Title: Shirasaka T, et al. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res. 1993 Sep 1;53(17):4004-9.

Title: Eraranta A, et al. Oxonic acid-induced hyperuricemia elevates plasma aldosterone in experimental renal insufficiency. J Hypertens. 2008 Aug;26(8):1661-8.

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