Title: Expression of CYP4V2 in human THP1 macrophages and its transcriptional regulation by peroxisome proliferator-activated receptor gamma.
Journal: Toxicology and applied pharmacology 20170901
Title: In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.
Journal: Molecular and cellular endocrinology 20140305
Title: Cisplatin inhibits testosterone synthesis by a mechanism that includes the action of reactive oxygen species (ROS) at the level of P450scc.
Journal: Chemico-biological interactions 20120930
Title: LXR agonists and ABCG1-dependent cholesterol efflux in MCF-7 breast cancer cells: relation to proliferation and apoptosis.
Journal: Anticancer research 20120701
Title: Dietary supplementation with 22-S-hydroxycholesterol to rats reduces body weight gain and the accumulation of liver triacylglycerol.
Journal: Lipids 20120501
Title: Liver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubule.
Journal: American journal of physiology. Renal physiology 20120301
Title: The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism.
Journal: The Journal of steroid biochemistry and molecular biology 20120201
Title: A steroid isolated from the water mold Achlya heterosexualis induces neurogenesis in vitro and in vivo.
Journal: Steroids 20120201
Title: Caprospinol: discovery of a steroid drug candidate to treat Alzheimer's disease based on 22R-hydroxycholesterol structure and properties.
Journal: Journal of neuroendocrinology 20120101
Title: Simvastatin reduces steroidogenesis by inhibiting Cyp17a1 gene expression in rat ovarian theca-interstitial cells.
Journal: Biology of reproduction 20120101
Title: Regulation of LXR by fatty acids, insulin, growth hormone and tumor necrosis factor-α in rainbow trout myocytes.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20111001
Title: Dysregulation of SREBP2 induces BACE1 expression.
Journal: Neurobiology of disease 20111001
Title: The human placenta expresses CYP17 and generates androgens de novo.
Journal: The Journal of clinical endocrinology and metabolism 20110501
Title: Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1.
Journal: The Journal of biological chemistry 20110218
Title: Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors.
Journal: Placenta 20110201
Title: Modulators of the hedgehog signaling pathway.
Journal: Bioorganic & medicinal chemistry 20100915
Title: Antiproliferative effect of LXR agonists T0901317 and 22(R)-hydroxycholesterol on multiple human cancer cell lines.
Journal: Anticancer research 20100901
Title: Testosterone synthesized in cultured human SZ95 sebocytes derives mainly from dehydroepiandrosterone.
Journal: Experimental dermatology 20100501
Title: Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-alpha.
Journal: The Journal of biological chemistry 20100416
Title: LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.
Journal: Atherosclerosis 20091101
Title: Effects of cholesterol and cAMP on progesterone production in cultured luteal cells isolated from pseudopregnant cat ovaries.
Journal: Animal reproduction science 20091001
Title: Mechanism underlying apolipoprotein E (ApoE) isoform-dependent lipid efflux from neural cells in culture.
Journal: Journal of neuroscience research 20090815
Title: OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids.
Journal: Journal of lipid research 20090701
Title: Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis.
Journal: Experimental dermatology 20090701
Title: Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS.
Journal: Journal of lipid research 20090201
Title: Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
Journal: Molecular pharmaceutics 20090101
Title: Androgen deprivation by activating the liver X receptor.
Journal: Endocrinology 20080801
Title: Epoxycholesterol impairs cholesteryl ester hydrolysis in macrophage foam cells, resulting in decreased cholesterol efflux.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080601
Title: Expression and biological activity of ABCA1 in alveolar epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20080301
Title: Fenvalerate inhibits progesterone production through cAMP-dependent signal pathway.
Journal: Toxicology letters 20080104
Title: 22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells.
Journal: Neuroscience 20070824
Title: Monobutyl phthalate inhibits steroidogenesis by downregulating steroidogenic acute regulatory protein expression in mouse Leydig tumor cells (MLTC-1).
Journal: Journal of toxicology and environmental health. Part A 20070601
Title: 22-Hydroxycholesterols regulate lipid metabolism differently than T0901317 in human myotubes.
Journal: Biochimica et biophysica acta 20061201
Title: Sesquiterpene lactone helenalin suppresses Leydig and adrenocortical cell steroidogenesis by inhibiting expression of the steroidogenic acute regulatory protein.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20061101
Title: Energized, polarized, and actively respiring mitochondria are required for acute Leydig cell steroidogenesis.
Journal: Endocrinology 20060801
Title: Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages.
Journal: Shock (Augusta, Ga.) 20060801
Title: HPLC method for quantification and characterization of cholesterol and its oxidation products in eggs.
Journal: Lipids 20060601
Title: Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20060401
Title: Carbaryl inhibits basal and FSH-induced progesterone biosynthesis of primary human granulosa-lutein cells.
Journal: Toxicology 20060301
Title: Arabidopsis CYP90B1 catalyses the early C-22 hydroxylation of C27, C28 and C29 sterols.
Journal: The Plant journal : for cell and molecular biology 20060301
Title: Suppression of inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 22(R)-hydroxycholesterol requires de novo protein synthesis in activated macrophages.
Journal: The Journal of steroid biochemistry and molecular biology 20051201
Title: Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line.
Journal: Placenta 20051101
Title: Liver X receptor and retinoic X receptor agonists modulate the expression of genes involved in lipid metabolism in human endothelial cells.
Journal: International journal of molecular medicine 20051001
Title: Osteogenic oxysterols inhibit the adverse effects of oxidative stress on osteogenic differentiation of marrow stromal cells.
Journal: Journal of cellular biochemistry 20050815
Title: Effects of fenvalerate on steroidogenesis in cultured rat granulosa cells.
Journal: Biomedical and environmental sciences : BES 20050401
Title: Regulatory mechanism of Toona sinensis on mouse leydig cell steroidogenesis.
Journal: Life sciences 20050211
Title: Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria.
Journal: Molecular endocrinology (Baltimore, Md.) 20050201
Title: Cellular physiology of cholesterol efflux in vascular endothelial cells.
Journal: Circulation 20041102
Title: Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism.
Journal: Journal of lipid research 20041101
Title: Evaluation of the role of FSH in regulation of Leydig cell function during different stages of its differentiation.
Journal: Molecular and cellular endocrinology 20040930
Title: Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040801
Title: The effect of LXR activators on AP-1 proteins in keratinocytes.
Journal: The Journal of investigative dermatology 20040701
Title: Oxidized LDL upregulated ATP binding cassette transporter-1 in THP-1 macrophages.
Journal: Acta pharmacologica Sinica 20040501
Title: Role of p160 coactivator complex in the activation of liver X receptor.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040401
Title: Oxysterols regulate expression of the steroidogenic acute regulatory protein.
Journal: Journal of molecular endocrinology 20040401
Title: Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter.
Journal: The Journal of biological chemistry 20040312
Title: Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040301
Title: Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis.
Journal: Hepatology (Baltimore, Md.) 20040301
Title: Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1).
Journal: The Journal of biological chemistry 20040227
Title: Inhibitory actions of lead on steroidogenesis in MA-10 mouse Leydig tumor cells.
Journal: Archives of andrology 20040101
Title: Identification of naturally occurring spirostenols preventing beta-amyloid-induced neurotoxicity.
Journal: Steroids 20040101
Title: Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells.
Journal: The Biochemical journal 20031201
Title: Identification and characterization of rodent ABCA1 in isolated type II pneumocytes.
Journal: American journal of physiology. Lung cellular and molecular physiology 20031001
Title: Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist.
Journal: The Journal of biological chemistry 20030919
Title: Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.
Journal: Molecular endocrinology (Baltimore, Md.) 20030701
Title: Oxysterols suppress constitutive fibrinogen expression.
Journal: Thrombosis and haemostasis 20030701
Title: Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1).
Journal: The Journal of investigative dermatology 20030601
Title: Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis.
Journal: FEBS letters 20030522
Title: The inhibitory effects of manganese on steroidogenesis in rat primary Leydig cells by disrupting steroidogenic acute regulatory (StAR) protein expression.
Journal: Toxicology 20030503
Title: Membrane incorporation of 22-hydroxycholesterol inhibits chemokine receptor activity.
Journal: Experimental cell research 20030501
Title: 22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.
Journal: The Journal of biological chemistry 20030411
Title: Formation and functioning of fused cholesterol side-chain cleavage enzymes.
Journal: DNA and cell biology 20030401
Title: Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha.
Journal: Molecular endocrinology (Baltimore, Md.) 20030301
Title: Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production.
Journal: The Journal of investigative dermatology 20030201
Title: Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes.
Journal: Biochemical and biophysical research communications 20021220
Title: 22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide.
Journal: Journal of neurochemistry 20021201
Title: Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol.
Journal: Journal of lipid research 20021101
Title: ATP-binding cassette transporter 1 participates in LDL oxidation by artery wall cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20021101
Title: Stimulation of progesterone production in human granulosa-lutein cells by lipoproteins: evidence for cholesterol-independent actions of high-density lipoproteins.
Journal: The Journal of endocrinology 20020401
Title: Alterations in ovarian follicular progesterone secretion by elevated exposures to the drinking water disinfection by-product dibromoacetic acid: examination of the potential site(s) of impact along the steroidogenic pathway.
Journal: Toxicology 20020227
Title: Macrophage cholesterol efflux to free apoprotein A-I in C3H and C57BL/6 mice.
Journal: Biochemical and biophysical research communications 20020208
Title: Expression and functional analyses of novel mutations of ATP-binding cassette transporter-1 in Japanese patients with high-density lipoprotein deficiency.
Journal: Biochemical and biophysical research communications 20020118
Title: Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis.
Journal: The Journal of investigative dermatology 20020101
Title: Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene.
Journal: Biochemical and biophysical research communications 20011005
Title: Leukemia inhibitory factor antagonizes gonadotropin induced-testosterone synthesis in cultured porcine leydig cells: sites of action.
Journal: Endocrinology 20010601
Title: Creation and activity of COS-1 cells stably expressing the F2 fusion of the human cholesterol side-chain cleavage enzyme system.
Journal: Endocrinology 20010601
Title: Luteinization factor-stimulated steroidogenesis in porcine granulosa cells.
Journal: General physiology and biophysics 20010601
Title: Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
Journal: Journal of medicinal chemistry 20010315
Title: Genomic sequence and structure of the human ABCG1 (ABC8) gene.
Journal: Biochemical and biophysical research communications 20010112
Title: The inhibitory effects of lead on steroidogenesis in MA-10 mouse Leydig tumor cells.
Journal: Life sciences 20010112
Title: Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
Journal: Gene 20010110
Title: Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells.
Journal: Journal of andrology 20010101
Title: Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19970513