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253-69-0,MFCD11521576
Catalog No.:AA00BG1O

253-69-0 | 1,7-Naphthyridine

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250mg
95%
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$485.00   $340.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BG1O
Chemical Name:
1,7-Naphthyridine
CAS Number:
253-69-0
Molecular Formula:
C8H6N2
Molecular Weight:
130.1466
MDL Number:
MFCD11521576
SMILES:
c1cnc2c(c1)ccnc2
Properties
Computed Properties
 
Complexity:
114  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
1.1  

Literature

Title: 1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase.

Journal: Journal of medicinal chemistry 20111124

Title: Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.

Journal: Journal of medicinal chemistry 20101111

Title: Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles.

Journal: Bioorganic & medicinal chemistry letters 20040322

Title: Pharmacological profile of a novel phosphodiesterase 4 inhibitor, 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridin-6-yl)-benzoic acid (NVP-ABE171), a 1,7-naphthyridine derivative, with anti-inflammatory activities.

Journal: The Journal of pharmacology and experimental therapeutics 20020401

Title: Synthesis of 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridine-6-yl)-benzoic acid: a potent and selective phosphodiesterase type 4D inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20020121

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Tags:253-69-0 Molecular Formula|253-69-0 MDL|253-69-0 SMILES|253-69-0 1,7-Naphthyridine