Title: Expression of cytochrome P450 epoxygenases and soluble epoxide hydrolase is regulated by hypolipidemic drugs in dose-dependent manner.
Journal: Toxicology and applied pharmacology 20180915
Title: Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations.
Journal: Toxicology 20170815
Title: Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.
Journal: Toxicology and applied pharmacology 20170301
Title: New brominated flame retardants and their metabolites as activators of the pregnane X receptor.
Journal: Toxicology letters 20160930
Title: Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.
Journal: Toxicology letters 20160122
Title: Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences.
Journal: The Journal of toxicological sciences 20160101
Title: Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.
Journal: Toxicology 20141003
Title: Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1).
Journal: Toxicology and applied pharmacology 20141001
Title: Gemfibrozil disrupts lysophosphatidylcholine and bile acid homeostasis via PPARα and its relevance to hepatotoxicity.
Journal: Archives of toxicology 20140401
Title: Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.
Journal: PloS one 20140101
Title: Development of surrogate correlation models to predict trace organic contaminant oxidation and microbial inactivation during ozonation.
Journal: Water research 20121201
Title: Occurrence of pharmaceutical compounds in wastewater and sludge from wastewater treatment plants: removal and ecotoxicological impact of wastewater discharges and sludge disposal.
Journal: Journal of hazardous materials 20121115
Title: Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas).
Journal: Environmental toxicology and chemistry 20121101
Title: Optimization of solid phase microextraction for non-lethal in vivo determination of selected pharmaceuticals in fish muscle using liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. A 20121026
Title: Environmental optimization of continuous flow ozonation for urban wastewater reclamation.
Journal: The Science of the total environment 20121015
Title: The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.
Journal: The Science of the total environment 20121015
Title: Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-β.
Journal: The Journal of biological chemistry 20121005
Title: Protective effects of peroxisome proliferator-activated receptor agonists on human podocytes: proposed mechanisms of action.
Journal: British journal of pharmacology 20121001
Title: Physiologically based modeling of pravastatin transporter-mediated hepatobiliary disposition and drug-drug interactions.
Journal: Pharmaceutical research 20121001
Title: Effects of effluent organic matter characteristics on the removal of bulk organic matter and selected pharmaceutically active compounds during managed aquifer recharge: Column study.
Journal: Journal of contaminant hydrology 20121001
Title: Managing the underestimated risk of statin-associated myopathy.
Journal: International journal of cardiology 20120906
Title: Use of fibrates in clinical practice: Queensland Lipid Group consensus recommendations.
Journal: International journal of evidence-based healthcare 20120901
Title: Prediction of the in vivo OATP1B1-mediated drug-drug interaction potential of an investigational drug against a range of statins.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830
Title: Gemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling 3 in glial cells: implications for neurodegenerative disorders.
Journal: The Journal of biological chemistry 20120803
Title: Gemfibrozil, a lipid lowering drug, inhibits the activation of primary human microglia via peroxisome proliferator-activated receptor β.
Journal: Neurochemical research 20120801
Title: Effect of gemfibrozil on the metabolism of brivaracetam in vitro and in human subjects.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120801
Title: The development, characterization, and application of an OATP1B1 inhibition assay in drug discovery.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120801
Title: Distribution and temporal evolution of pharmaceutically active compounds alongside sewage sludge treatment. Risk assessment of sludge application onto soils.
Journal: Journal of environmental management 20120715
Title: Design and optimization of self-nanoemulsifying drug delivery systems (SNEDDS) for enhanced dissolution of gemfibrozil.
Journal: International journal of pharmaceutics 20120715
Title: Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120715
Title: Persistent use of against-label statin-fibrate combinations from 2003-2009 despite United States Food and Drug Administration dose restrictions.
Journal: Pharmacotherapy 20120701
Title: Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
Journal: Journal of medicinal chemistry 20120614
Title: In vitro antimalarial activity and drug interactions of fenofibric acid.
Journal: Antimicrobial agents and chemotherapy 20120601
Title: Evaluating pharmaceuticals and caffeine as indicators of fecal contamination in drinking water sources of the Greater Montreal region.
Journal: Chemosphere 20120601
Title: A review of time courses and predictors of lipid changes with fenofibric acid-statin combination.
Journal: Cardiovascular drugs and therapy 20120601
Title: HDL cholesterol--how do I raise my patients good cholesterol?
Journal: JPMA. The Journal of the Pakistan Medical Association 20120601
Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal: Journal of medicinal chemistry 20120524
Title: Protective effect of T. violacea rhizome extract against hypercholesterolemia-induced oxidative stress in Wistar rats.
Journal: Molecules (Basel, Switzerland) 20120521
Title: Analytical and biological characterization of halogenated gemfibrozil produced through chlorination of wastewater.
Journal: Environmental science & technology 20120515
Title: Deletion of GPIHBP1 causing severe chylomicronemia.
Journal: Journal of inherited metabolic disease 20120501
Title: Pharmacokinetic drug interaction between gemfibrozil and sitagliptin in healthy Indian male volunteers.
Journal: European journal of clinical pharmacology 20120501
Title: Biological removal of pharmaceuticals and personal care products during laboratory soil aquifer treatment simulation with different primary substrate concentrations.
Journal: Water research 20120501
Title: Occurrence and persistence of organic emerging contaminants and priority pollutants in five sewage treatment plants of Spain: two years pilot survey monitoring.
Journal: Environmental pollution (Barking, Essex : 1987) 20120501
Title: Gemfibrozil is a strong inactivator of CYP2C8 in very small multiple doses.
Journal: Clinical pharmacology and therapeutics 20120501
Title: Occurrence and removal of pharmaceuticals in wastewater treatment plants at the Spanish Mediterranean area of Valencia.
Journal: Chemosphere 20120401
Title: Characterization of in vitro glucuronidation clearance of a range of drugs in human kidney microsomes: comparison with liver and intestinal glucuronidation and impact of albumin.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120401
Title: Determination of pharmaceuticals and antiseptics in water by solid-phase extraction and gas chromatography/mass spectrometry: analysis via pentafluorobenzylation and stable isotope dilution.
Journal: Analytical and bioanalytical chemistry 20120401
Title: Indole-based fibrates as potential hypolipidemic and antiobesity agents.
Journal: Journal of medicinal chemistry 20120322
Title: Suspended biofilm carrier and activated sludge removal of acidic pharmaceuticals.
Journal: Water research 20120315
Title: Formulation of poorly water-soluble Gemfibrozil applying power ultrasound.
Journal: Ultrasonics sonochemistry 20120301
Title: In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120301
Title: Occurrence, fate, and persistence of gemfibrozil in water and soil.
Journal: Environmental toxicology and chemistry 20120301
Title: Mitochondrial oxidative stress alters a pathway in Caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates.
Journal: PLoS genetics 20120301
Title: Antihypercholesterolaemic influence of dietary tender cluster beans (Cyamopsis tetragonoloba) in cholesterol fed rats.
Journal: The Indian journal of medical research 20120301
Title: Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases.
Journal: Archives of medical science : AMS 20120227
Title: CYP2C8 but not CYP3A4 is important in the pharmacokinetics of montelukast.
Journal: British journal of clinical pharmacology 20120201
Title: In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.
Journal: Pharmaceutical research 20120201
Title: Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120201
Title: Effects of Fenton treatment on the properties of effluent organic matter and their relationships with the degradation of pharmaceuticals and personal care products.
Journal: Water research 20120201
Title: Hypertriglyceridemia-induced acute pancreatitis treated with insulin and heparin.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120201
Title: The cardiovascular effects of peroxisome proliferator-activated receptor agonists.
Journal: The American journal of medicine 20120201
Title: The prevalence, awareness and treatment of high low density lipoprotein-cholesterol in korean adults without coronary heart diseases - the third Korea national health and nutrition examination survey, 2005 -.
Journal: Korean circulation journal 20120201
Title: Analysis of endocrine disrupting compounds, pharmaceuticals and personal care products in sewage sludge by gas chromatography-mass spectrometry.
Journal: Talanta 20120130
Title: Effect of dietary fatty acid composition on food intake, triglycerides, and hypothalamic peptides.
Journal: Regulatory peptides 20120110
Title: DSC, X-ray and FTIR studies of a gemfibrozil/dimethyl-β-cyclodextrin inclusion complex produced by co-grinding.
Journal: Journal of pharmaceutical and biomedical analysis 20120105
Title: Genotoxic effects in fish induced by pharmacological agents present in the sewage of some Italian water-treatment plants.
Journal: Environmental toxicology 20120101
Title: Occurrence of pharmaceutical compounds in wastewater process streams in Dublin, Ireland.
Journal: Environmental monitoring and assessment 20120101
Title: A role for peroxisome proliferator-activated receptors in the immunopathology of schistosomiasis?
Journal: PPAR research 20120101
Title: Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution.
Journal: International journal of vascular medicine 20120101
Title: Toxicity of mixtures of perfluorooctane sulphonic acid with chlorinated chemicals and lipid regulators.
Journal: Chemosphere 20120101
Title: Development of a bar adsorptive micro-extraction-large-volume injection-gas chromatography-mass spectrometric method for pharmaceuticals and personal care products in environmental water matrices.
Journal: Analytical and bioanalytical chemistry 20120101
Title: Impact of the counterion on the solubility and physicochemical properties of salts of carboxylic acid drugs.
Journal: Drug development and industrial pharmacy 20120101
Title: Is RORγ a therapeutic target for treating Mycobacterium tuberculosis infections?
Journal: Tuberculosis (Edinburgh, Scotland) 20120101
Title: Nuclear receptors in nonalcoholic Fatty liver disease.
Journal: Journal of lipids 20120101
Title: Current status of the immunomodulation and immunomediated therapeutic strategies for multiple sclerosis.
Journal: Clinical & developmental immunology 20120101
Title: Indicators of the atherogenic lipoprotein phenotype measured with density gradient ultracentrifugation predict changes in carotid intima-media thickness in men and women.
Journal: Vascular health and risk management 20120101
Title: Metabolic syndrome in the Mediterranean region: Current status.
Journal: Indian journal of endocrinology and metabolism 20120101
Title: Hypertriglyceridemia-induced recurrent acute pancreatitis: A case-based review.
Journal: Indian journal of endocrinology and metabolism 20120101
Title: Development and validation of a repharsed phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma.
Journal: Chemistry Central journal 20120101
Title: Relaxation of rat thoracic aorta by fibrate drugs correlates with their potency to disturb intracellular calcium of VSMCs.
Journal: Vascular pharmacology 20120101
Title: PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways.
Journal: PPAR research 20120101
Title: Niacin extended-release/simvastatin combination therapy produces larger favorable changes in high-density lipoprotein particles than atorvastatin monotherapy.
Journal: Vascular health and risk management 20120101
Title: Effect of gemfibrozil on the pharmacokinetics of mitiglinide in rats.
Journal: Arzneimittel-Forschung 20120101
Title: 5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability.
Journal: Journal of neuroinflammation 20120101
Title: Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles.
Journal: International journal of nanomedicine 20120101
Title: Chemosensitization as a means to augment commercial antifungal agents.
Journal: Frontiers in microbiology 20120101
Title: Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study.
Journal: Cardiovascular diabetology 20120101
Title: Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease.
Journal: Clinical Medicine Insights. Cardiology 20120101
Title: The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes.
Journal: PPAR research 20120101
Title: Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies.
Journal: Nutrition & metabolism 20120101
Title: Achieving secondary prevention low-density lipoprotein particle concentration goals using lipoprotein cholesterol-based data.
Journal: PloS one 20120101
Title: New insights into the role of peroxisome proliferator-activated receptors in regulating the inflammatory response after tissue injury.
Journal: PPAR research 20120101
Title: Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.
Journal: International journal of Alzheimer's disease 20120101
Title: The promoter of Rv0560c is induced by salicylate and structurally-related compounds in Mycobacterium tuberculosis.
Journal: PloS one 20120101
Title: Cardiovascular events in patients received combined fibrate/statin treatment versus statin monotherapy: Acute Coronary Syndrome Israeli Surveys data.
Journal: PloS one 20120101
Title: A comparative clinical study of hypolipidemic efficacy of Amla (Emblica officinalis) with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitor simvastatin.
Journal: Indian journal of pharmacology 20120101
Title: Fenofibrate enhances the in vitro differentiation of foxp3(+) regulatory T cells in mice.
Journal: PPAR research 20120101
Title: Systematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetine.
Journal: PloS one 20120101
Title: Failure to Control Caries in an AIDS-Affected Individual: A Case Report.
Journal: Case reports in dentistry 20120101
Title: Identification of amino acids essential for estrone-3-sulfate transport within transmembrane domain 2 of organic anion transporting polypeptide 1B1.
Journal: PloS one 20120101
Title: Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach.
Journal: PloS one 20120101
Title: All-Trans Retinoic Acid-Induced Pseudotumor Cerebri during Induction Therapy for Acute Promyelocytic Leukemia: A Case Report and Literature Review.
Journal: Case reports in oncological medicine 20120101
Title: Removal of pharmaceuticals in biologically treated wastewater by chlorine dioxide or peracetic acid.
Journal: Environmental technology 20120101
Title: Leaching of pharmaceuticals and personal care products in turfgrass soils during recycled water irrigation.
Journal: Journal of environmental quality 20120101
Title: Immunotoxic potential of aeration lagoon effluents for the treatment of domestic and hospital wastewaters in the freshwater mussel Elliptio complanata.
Journal: Journal of environmental sciences (China) 20120101
Title: A neutral risk on the development of new-onset diabetes mellitus (NODM) in Taiwanese patients with dyslipidaemia treated with fibrates.
Journal: TheScientificWorldJournal 20120101
Title: Removal of trace organic chemical contaminants by a membrane bioreactor.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20120101
Title: PPARα-Independent Arterial Smooth Muscle Relaxant Effects of PPARα Agonists.
Journal: PPAR research 20120101
Title: Patient with hypertriglyceridemia, type 2 diabetes, and chronic kidney disease treated with atorvastatin and omega-3 Fatty Acid ethyl esters.
Journal: The open cardiovascular medicine journal 20120101
Title: IMproving the imPlemEntation of cuRrent guidelines for the mAnagement of major coronary hearT disease rIsk factors by multifactorial interVEntion. The IMPERATIVE renal analysis.
Journal: Archives of medical science : AMS 20111231
Title: Reconnaissance of selected PPCP compounds in Costa Rican surface waters.
Journal: Water research 20111215
Title: Studies to further investigate the inhibition of human liver microsomal CYP2C8 by the acyl-β-glucuronide of gemfibrozil.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111201
Title: Familial hypercholesterolemia: present and future management.
Journal: Current cardiology reports 20111201
Title: The PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice.
Journal: Experimental neurology 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: High levels of remnant lipoprotein cholesterol is a risk factor for large artery atherosclerotic stroke.
Journal: Journal of clinical neurology (Seoul, Korea) 20111201
Title: The effect of bezafibrate and omega-3 fatty acids on lymphocyte cytokine release and systemic inflammation in patients with isolated hypertriglyceridemia.
Journal: European journal of clinical pharmacology 20111101
Title: Synthesis of novel N-(2-hydroxy-2-p-tolylethyl)-amide and N-(2-oxo-2-p-tolylethyl)-amide derivatives and their antidyslipidemic and antioxidant activity.
Journal: Bioorganic & medicinal chemistry letters 20111101
Title: Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
Journal: Chemosphere 20111101
Title: The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis.
Journal: Korean circulation journal 20111101
Title: Evaluation of enhanced coagulation pretreatment to improve ozone oxidation efficiency in wastewater.
Journal: Water research 20111015
Title: Dose-dependent interaction between gemfibrozil and repaglinide in humans: strong inhibition of CYP2C8 with subtherapeutic gemfibrozil doses.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20111001
Title: Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.
Journal: Marine pollution bulletin 20111001
Title: Temporal variation of pharmaceuticals in an urban and agriculturally influenced stream.
Journal: The Science of the total environment 20111001
Title: Gemfibrozil hepatotoxicity: a case report.
Journal: International journal of clinical pharmacy 20111001
Title: Discovery of gemfibrozil analogues that activate PPARα and enhance the expression of gene CPT1A involved in fatty acids catabolism.
Journal: European journal of medicinal chemistry 20111001
Title: Incidence of hospitalized rhabdomyolysis with statin and fibrate use in an insured US population.
Journal: The Annals of pharmacotherapy 20111001
Title: Trace analysis of acidic pharmaceutical residues in waters with isotope dilution gas chromatography-mass spectrometry via methylation derivatization.
Journal: Talanta 20110930
Title: Dual role of physical workload and occupational noise in the association of the metabolic syndrome with risk of coronary heart disease: findings from the Helsinki Heart Study.
Journal: Occupational and environmental medicine 20110901
Title: Impact of intestinal glucuronidation on the pharmacokinetics of raloxifene.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901
Title: [Study on the pharmacokinetics of tashinone II(A) -loaded polylactic acid nanoparticles in rabbit].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110901
Title: PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation.
Journal: Biochimica et biophysica acta 20110801
Title: Fenofibrate: a review of its lipid-modifying effects in dyslipidemia and its vascular effects in type 2 diabetes mellitus.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110801
Title: Reversal of drug-induced rhabdomyolysis on bone scan.
Journal: Clinical nuclear medicine 20110801
Title: Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy.
Journal: Diabetes & metabolism journal 20110801
Title: Ask the doctor. On my last blood test, my triglycerides were 280. Should I be worried about that? My doctor wants me to start taking something called Lopid. Is there another solution?
Journal: Harvard heart letter : from Harvard Medical School 20110801
Title: Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure.
Journal: British journal of pharmacology 20110701
Title: Effect of statin and fibrate treatment on inflammation in type 2 diabetes. A randomized, cross-over study.
Journal: Diabetes research and clinical practice 20110701
Title: Aquivalence revisited--new model formulation and application to assess environmental fate of ionic pharmaceuticals in Hamilton Harbour, Lake Ontario.
Journal: Environment international 20110701
Title: Effects of the pharmaceuticals gemfibrozil and diclofenac on biomarker expression in the zebra mussel (Dreissena polymorpha) and their comparison with standardised toxicity tests.
Journal: Chemosphere 20110701
Title: Effects of the pharmaceuticals gemfibrozil and diclofenac on the marine mussel (Mytilus spp.) and their comparison with standardized toxicity tests.
Journal: Marine pollution bulletin 20110701
Title: Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions.
Journal: Water research 20110701
Title: Monitoring of pharmaceutically active compounds on the Guadalquivir River basin (Spain): occurrence and risk assessment.
Journal: Journal of environmental monitoring : JEM 20110701
Title: Synthesis, characterization and in vitro hydrolysis of a gemfibrozil-nicotinic acid codrug for improvement of lipid profile.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614
Title: The influence of gemfibrozil on malondialdehyde level and paraoxonase 1 activity in wistar and fisher rats.
Journal: Basic & clinical pharmacology & toxicology 20110601
Title: Clinical importance of OATP1B1 and OATP1B3 in drug-drug interactions.
Journal: Drug metabolism and pharmacokinetics 20110601
Title: Prediction of the overall renal tubular secretion and hepatic clearance of anionic drugs and a renal drug-drug interaction involving organic anion transporter 3 in humans by in vitro uptake experiments.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601
Title: Cytotoxicity assessment of four pharmaceutical compounds on the zebra mussel (Dreissena polymorpha) haemocytes, gill and digestive gland primary cell cultures.
Journal: Chemosphere 20110601
Title: Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.
Journal: European heart journal 20110601
Title: Fenofibrate: altered renal function.
Journal: Prescrire international 20110601
Title: Applicability of sucrose laurate as surfactant in solid dispersions prepared by melt technology.
Journal: International journal of pharmaceutics 20110530
Title: Comparison of four extraction methods for the analysis of pharmaceuticals in wastewater.
Journal: Journal of chromatography. A 20110506
Title: Human pharmacokinetic prediction of UDP-glucuronosyltransferase substrates with an animal scale-up approach.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110501
Title: Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110501
Title: The effect of gemfibrozil, niacin and cholestyramine combination therapy on metabolic syndrome in the Armed Forces Regression Study.
Journal: The American journal of the medical sciences 20110501
Title: Native low-density lipoprotein-dependent interleukin-8 production through pertussis toxin-sensitive G-protein coupled receptors and hydrogen peroxide generation contributes to migration of human aortic smooth muscle cells.
Journal: Yonsei medical journal 20110501
Title: Effects of selected pharmaceutically active compounds on treatment performance in sequencing batch reactors mimicking wastewater treatment plants operations.
Journal: Water research 20110501
Title: Sweet potato (Ipomoea batatas L.) leaves suppressed oxidation of low density lipoprotein (LDL) in vitro and in human subjects.
Journal: Journal of clinical biochemistry and nutrition 20110501
Title: Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans.
Journal: Aging 20110501
Title: Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in different biological wastewater treatment processes.
Journal: Environmental science & technology 20110415
Title: Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes.
Journal: Toxicology letters 20110410
Title: Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans.
Journal: Clinical pharmacology and therapeutics 20110401
Title: Occurrence and behavior of non-steroidal anti-inflammatory drugs and lipid regulators in wastewater and urban river water of the Pearl River Delta, South China.
Journal: Journal of environmental monitoring : JEM 20110401
Title: The causes and consequences of low levels of high density lipoproteins in patients with diabetes.
Journal: Diabetes & metabolism journal 20110401
Title: Use of fibrates in the United States and Canada.
Journal: JAMA 20110323
Title: The fibrate drug gemfibrozil disrupts lipoprotein metabolism in rainbow trout.
Journal: Toxicology and applied pharmacology 20110315
Title: Pharmaceuticals, hormones and bisphenol A in untreated source and finished drinking water in Ontario, Canada--occurrence and treatment efficiency.
Journal: The Science of the total environment 20110315
Title: Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin.
Journal: Journal of clinical pharmacology 20110301
Title: Rapid reduction of severely elevated serum triglycerides with insulin infusion, gemfibrozil and niacin.
Journal: Clinical medicine & research 20110301
Title: Fibrate use in diabetes: new concepts.
Journal: Journal of diabetes 20110301
Title: Depressogenic effects of medications: a review.
Journal: Dialogues in clinical neuroscience 20110301
Title: Nutritional and metabolic status of HIV-positive patients with lipodystrophy during one year of follow-up.
Journal: Clinics (Sao Paulo, Brazil) 20110301
Title: Biphasic regulation of intracellular calcium by gemfibrozil contributes to inhibiting L6 myoblast differentiation: implications for clinical myotoxicity.
Journal: Chemical research in toxicology 20110218
Title: Two-step stacking in capillary zone electrophoresis featuring sweeping and micelle to solvent stacking: II. Organic anions.
Journal: Journal of chromatography. A 20110218
Title: Attenuation of contaminants of emerging concern during surface-spreading aquifer recharge.
Journal: The Science of the total environment 20110215
Title: The CYP2C8 inhibitor gemfibrozil does not affect the pharmacokinetics of zafirlukast.
Journal: European journal of clinical pharmacology 20110201
Title: Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP?
Journal: Current atherosclerosis reports 20110201
Title: Effluent-dominated streams. Part 2: Presence and possible effects of pharmaceuticals and personal care products in Wascana Creek, Saskatchewan, Canada.
Journal: Environmental toxicology and chemistry 20110201
Title: Analysis of the presence of cardiovascular and analgesic/anti-inflammatory/antipyretic pharmaceuticals in river- and drinking-water of the Madrid Region in Spain.
Journal: Chemosphere 20110201
Title: Differential effects of gemfibrozil and fenofibrate on reverse cholesterol transport from macrophages to feces in vivo.
Journal: Biochimica et biophysica acta 20110201
Title: Impact of obesity on hypertension-induced cardiac remodeling: role of oxidative stress and its modulation by gemfibrozil treatment in rats.
Journal: Free radical biology & medicine 20110115
Title: The subtypes of peroxisome proliferator-activated receptors expressed by human podocytes and their role in decreasing podocyte injury.
Journal: British journal of pharmacology 20110101
Title: Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: Cleanup strategies and advantages in the determination of several therapeutic classes of pharmaceuticals in wastewater samples by SPE-LC-MS/MS.
Journal: Analytical and bioanalytical chemistry 20110101
Title: Effects of selected pharmaceutically active compounds on the ammonia oxidizing bacterium Nitrosomonas europaea.
Journal: Chemosphere 20110101
Title: Identification of reaction products from reactions of free chlorine with the lipid-regulator gemfibrozil.
Journal: Water research 20110101
Title: Standards of medical care in diabetes--2011.
Journal: Diabetes care 20110101
Title: Transforming Growth Factor-β1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome.
Journal: Cardiology research and practice 20110101
Title: Atherosclerosis and thrombosis: insights from large animal models.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Comparative effectiveness of guidelines for the management of hyperlipidemia and hypertension for type 2 diabetes patients.
Journal: PloS one 20110101
Title: Megalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal function.
Journal: PloS one 20110101
Title: Effects of currently prescribed LDL-C-lowering drugs on PCSK9 and implications for the next generation of LDL-C-lowering agents.
Journal: Lipids in health and disease 20110101
Title: A Canadian Critical Care Trials Group project in collaboration with the international forum for acute care trialists - Collaborative H1N1 Adjuvant Treatment pilot trial (CHAT): study protocol and design of a randomized controlled trial.
Journal: Trials 20110101
Title: Induction of P450 3A1/2 and 2C6 by gemfibrozil in Sprague-Dawley rats.
Journal: Pharmacological reports : PR 20110101
Title: Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy.
Journal: Lipids in health and disease 20110101
Title: Effects of short-term treatment with atorvastatin in smokers with asthma--a randomized controlled trial.
Journal: BMC pulmonary medicine 20110101
Title: Drug induced psoriasis.
Journal: Acta dermatovenerologica Croatica : ADC 20110101
Title: The role of high-density lipoproteins in reducing the risk of vascular diseases, neurogenerative disorders, and cancer.
Journal: Cholesterol 20110101
Title: Characteristics of high-density lipoprotein subclasses distribution for subjects with desirable total cholesterol levels.
Journal: Lipids in health and disease 20110101
Title: [Amorphous form in pharmaceutical technological research].
Journal: Acta pharmaceutica Hungarica 20110101
Title: Platinum agent-induced hypersensitivity reactions: data mining of the public version of the FDA adverse event reporting system, AERS.
Journal: International journal of medical sciences 20110101
Title: Dyslipidemia associated with chronic kidney disease.
Journal: The open cardiovascular medicine journal 20110101
Title: HIV and HAART-Associated Dyslipidemia.
Journal: The open cardiovascular medicine journal 20110101
Title: Prosthetic aortic valve stenosis in end-stage renal failure.
Journal: International journal of nephrology 20110101
Title: An international randomised placebo-controlled trial of a four-component combination pill ('polypill') in people with raised cardiovascular risk.
Journal: PloS one 20110101
Title: Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment.
Journal: The open cardiovascular medicine journal 20110101
Title: Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma.
Journal: Chemistry Central journal 20110101
Title: Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation.
Journal: Vascular health and risk management 20110101
Title: Possible involvement of caveolin in attenuation of cardioprotective effect of ischemic preconditioning in diabetic rat heart.
Journal: BMC cardiovascular disorders 20110101
Title: Targeting Nuclear Hormone Receptors: PPARα Agonists as Potential Disease-Modifying Drugs for Rheumatoid Arthritis.
Journal: International journal of rheumatology 20110101
Title: Treating statin-intolerant patients.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Title: Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey.
Journal: Drug design, development and therapy 20110101
Title: Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis.
Journal: Frontiers in pharmacology 20110101
Title: Stepwise approach to myopathy in systemic disease.
Journal: Frontiers in neurology 20110101
Title: Spinal cord injury: From inflammation to glial scar.
Journal: Surgical neurology international 20110101
Title: The role of common variants of the cholesteryl ester transfer protein gene in left main coronary artery disease.
Journal: Lipids in health and disease 20110101
Title: Sinomenine inhibits microglial activation by Aβ and confers neuroprotection.
Journal: Journal of neuroinflammation 20110101
Title: RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome.
Journal: PloS one 20110101
Title: Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A₂ (Lp-PLA₂): a review.
Journal: Lipids in health and disease 20110101
Title: Rhabdomyolysis associated with fenofibrate monotherapy in a patient with chronic myelogenous leukemia.
Journal: Case reports in gastroenterology 20110101
Title: Medicinal Chemistry and Actions of Dual and Pan PPAR Modulators.
Journal: The open medicinal chemistry journal 20110101
Title: Prevalence, Predictors, and Impact of Low High-Density Lipoprotein Cholesterol on in-Hospital Outcomes Among Acute Coronary Syndrome Patients in the Middle East.
Journal: The open cardiovascular medicine journal 20110101
Title: Long-term fenofibrate treatment impaired glucose-stimulated insulin secretion and up-regulated pancreatic NF-kappa B and iNOS expression in monosodium glutamate-induced obese rats: is that a latent disadvantage?
Journal: Journal of translational medicine 20110101
Title: Multimodal cardiovascular magnetic resonance quantifies regional variation in vascular structure and function in patients with coronary artery disease: relationships with coronary disease severity.
Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101
Title: Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin.
Journal: Lipids in health and disease 20110101
Title: 13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages.
Journal: Lipids in health and disease 20110101
Title: Characterization of Abcc4 gene amplification in stepwise-selected mouse J774 macrophages resistant to the topoisomerase II inhibitor ciprofloxacin.
Journal: PloS one 20110101
Title: Rosiglitazone and fenofibrate additive effects on lipids.
Journal: Cholesterol 20110101
Title: Calciphylaxis presenting in early chronic kidney disease with mixed hyperparathyroidism.
Journal: International journal of nephrology and renovascular disease 20110101
Title: Association of PPARα Intron 7 Polymorphism with Coronary Artery Disease: A Cross-Sectional Study.
Journal: ISRN cardiology 20110101
Title: No consensus on definition criteria for stroke registry common data elements.
Journal: Cerebrovascular diseases extra 20110101
Title: Statins: past and present.
Journal: Heart views : the official journal of the Gulf Heart Association 20110101
Title: Using Complementary and Alternative Medicines to Target the Host Response during Severe Influenza.
Journal: Evidence-based complementary and alternative medicine : eCAM 20101201
Title: Impact of increases in high-density lipoprotein cholesterol on cardiovascular outcomes during the armed forces regression study.
Journal: Journal of cardiovascular pharmacology and therapeutics 20101201
Title: Occurrence and loss over three years of 72 pharmaceuticals and personal care products from biosolids-soil mixtures in outdoor mesocosms.
Journal: Water research 20101201
Title: CXCL9 and CXCL11 chemokines modulation by peroxisome proliferator-activated receptor-alpha agonists secretion in Graves' and normal thyrocytes.
Journal: The Journal of clinical endocrinology and metabolism 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.
Journal: Journal of lipid research 20101201
Title: Statins alter intracellular calcium homeostasis in malignant hyperthermia susceptible individuals.
Journal: Cardiovascular therapeutics 20101201
Title: Validation of an LC/MS method for the determination of gemfibrozil in human plasma and its application to a pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20101201
Title: Repaglinide-gemfibrozil drug interaction: inhibition of repaglinide glucuronidation as a potential additional contributing mechanism.
Journal: British journal of clinical pharmacology 20101201
Title: Successful drug development despite adverse preclinical findings part 2: examples.
Journal: Journal of toxicologic pathology 20101201
Title: Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain).
Journal: Journal of hazardous materials 20101115
Title: Chronic treatment with fibrates elevates superoxide dismutase in adult mouse brain microvessels.
Journal: Brain research 20101104
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Comparative physical, mechanical and crystallographic properties of a series of gemfibrozil salts.
Journal: The Journal of pharmacy and pharmacology 20101101
Title: Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.
Journal: International journal of environmental research and public health 20101101
Title: Diabetes & coronary heart disease: current perspectives.
Journal: The Indian journal of medical research 20101101
Title: Two different spectrofluorimetric methods for simultaneous determination of gemfibrozil and rosiglitazone in human plasma.
Journal: Talanta 20101015
Title: Atherogenic dyslipidemia: cardiovascular risk and dietary intervention.
Journal: Lipids 20101001
Title: Cerivastatin in vitro metabolism by CYP2C8 variants found in patients experiencing rhabdomyolysis.
Journal: Pharmacogenetics and genomics 20101001
Title: [Facial edema due to gemfibrozil].
Journal: Medicina clinica 20100911
Title: Lipid Lowering Activity of Anthocephalus indicus Root in Hyperlipidemic Rats.
Journal: Evidence-based complementary and alternative medicine : eCAM 20100901
Title: Effect of a single gemfibrozil dose on the pharmacokinetics of rosuvastatin in bile and plasma in healthy volunteers.
Journal: Journal of clinical pharmacology 20100901
Title: Application of a novel solid-phase-extraction sampler and ultra-performance liquid chromatography quadrupole-time-of-flight mass spectrometry for determination of pharmaceutical residues in surface sea water.
Journal: Chemosphere 20100901
Title: Results of a safety initiative for patients on concomitant amiodarone and simvastatin therapy in a Veterans Affairs medical center.
Journal: Journal of managed care pharmacy : JMCP 20100901
Title: Evolution of absorbance spectra of ozonated wastewater and its relationship with the degradation of trace-level organic species.
Journal: Environmental science & technology 20100815
Title: Management of hypertriglyceridemia in the diabetic patient.
Journal: Current diabetes reports 20100801
Title: Gemfibrozil markedly increases the plasma concentrations of montelukast: a previously unrecognized role for CYP2C8 in the metabolism of montelukast.
Journal: Clinical pharmacology and therapeutics 20100801
Title: Antihyperlipidemic activity of Clitoria ternatea and Vigna mungo in rats.
Journal: Pharmaceutical biology 20100801
Title: Occurrence and risk assessment of acidic pharmaceuticals in the Yellow River, Hai River and Liao River of north China.
Journal: The Science of the total environment 20100715
Title: Novel coumarin derivatives as potential antidyslipidemic agents.
Journal: Bioorganic & medicinal chemistry letters 20100715
Title: Role of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice.
Journal: The pharmacogenomics journal 20100601
Title: Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents.
Journal: Bioorganic & medicinal chemistry 20100601
Title: Multi-residue method for the analysis of pharmaceutical compounds in sewage sludge, compost and sediments by sonication-assisted extraction and LC determination.
Journal: Journal of separation science 20100601
Title: Systematic review on evidence of the effectiveness of cholesterol-lowering drugs.
Journal: Advances in therapy 20100601
Title: Occurrence and a screening-level risk assessment of human pharmaceuticals in the Pearl River system, South China.
Journal: Environmental toxicology and chemistry 20100601
Title: Presence of pharmaceutically active compounds in Doñana Park (Spain) main watersheds.
Journal: Journal of hazardous materials 20100515
Title: Synthesis of novel benzocoumarin derivatives as lipid lowering agents.
Journal: Bioorganic & medicinal chemistry letters 20100515
Title: Occurrence and fate of pharmaceuticals in wastewater treatment plants and rivers in Korea.
Journal: Environmental pollution (Barking, Essex : 1987) 20100501
Title: Suppressive effect of insulin infusion on chemokines and chemokine receptors.
Journal: Diabetes care 20100501
Title: The nasty surprise of a complex drug-drug interaction.
Journal: Drug discovery today 20100501
Title: Tissue-specific in vivo bioconcentration of pharmaceuticals in rainbow trout (Oncorhynchus mykiss) using space-resolved solid-phase microextraction.
Journal: Environmental science & technology 20100501
Title: Potential chemical and microbiological risks on human health from urban wastewater reuse in agriculture. Case study of wastewater effluents in Spain.
Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20100501
Title: Clinical management of pandemic 2009 influenza A(H1N1) infection.
Journal: Chest 20100401
Title: Effects of statins vs. non-statin lipid-lowering therapy on bone formation and bone mineral density biomarkers in patients with hyperlipidemia.
Journal: Bone 20100401
Title: [Problems with statins and the marketing of these medications].
Journal: Revista medica de Chile 20100401
Title: Expression of prestin and Gata-3,-2,-1 mRNA in the rat organ of Corti during the postnatal period and in culture.
Journal: Hearing research 20100301
Title: Effect of auxiliary substances on complexation efficiency and intrinsic dissolution rate of gemfibrozil-beta-CD complexes.
Journal: AAPS PharmSciTech 20100301
Title: Management of dyslipidemia in people with type 2 diabetes mellitus.
Journal: Reviews in endocrine & metabolic disorders 20100301
Title: Study on the matrix effect in the determination of selected pharmaceutical residues in seawater by solid-phase extraction and ultra-high-performance liquid chromatography-electrospray ionization low-energy collision-induced dissociation tandem mass spectrometry.
Journal: Journal of chromatography. A 20100226
Title: Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100215
Title: Combined therapy in the treatment of dyslipidemia.
Journal: Fundamental & clinical pharmacology 20100201
Title: Synthesis and biological evaluation of N-aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents.
Journal: European journal of medicinal chemistry 20100201
Title: Safety and tolerability of dalcetrapib (RO4607381/JTT-705): results from a 48-week trial.
Journal: European heart journal 20100201
Title: Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk.
Journal: The American journal of medicine 20100201
Title: Simultaneous determination of acidic, neutral and basic pharmaceuticals in urban wastewater by ultra high-pressure liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. A 20100129
Title: Lipid metabolism and hyperlipidemia in dogs.
Journal: Veterinary journal (London, England : 1997) 20100101
Title: Ecotoxicity assessment of lipid regulators in water and biologically treated wastewater using three aquatic organisms.
Journal: Environmental science and pollution research international 20100101
Title: Role of PPARs in Radiation-Induced Brain Injury.
Journal: PPAR research 20100101
Title: Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors.
Journal: European heart journal 20100101
Title: HIV-associated dyslipidaemia among HIV antibody-positive patients in Ireland: prevalence and management strategies.
Journal: International journal of STD & AIDS 20100101
Title: Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100101
Title: Gemfibrozil-induced myositis in a patient with normal renal function.
Journal: The Annals of pharmacotherapy 20100101
Title: A synergism model for PPARalpha and PXR agonist effects on HDL-cholesterol and apoA1.
Journal: Frontiers in bioscience (Elite edition) 20100101
Title: Standards of medical care in diabetes--2010.
Journal: Diabetes care 20100101
Title: Erythema multiforme associated with gemfibrozil monotherapy.
Journal: The American journal of the medical sciences 20100101
Title: Implications of human pharmaceutical occurrence in the Sindian river of Taiwan: a strategic study of risk assessment.
Journal: Journal of environmental monitoring : JEM 20100101
Title: Rosuvastatin-associated adverse effects and drug-drug interactions in the clinical setting of dyslipidemia.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101
Title: Peroxisome proliferator-activated receptor (PPAR): balance for survival in parasitic infections.
Journal: Journal of biomedicine & biotechnology 20100101
Title: System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: human hepatocytes versus liver microsomes versus recombinant enzymes.
Journal: Drug metabolism and pharmacokinetics 20100101
Title: EVITA: a tool for the early evaluation of pharmaceutical innovations with regard to therapeutic advantage.
Journal: BMC clinical pharmacology 20100101
Title: Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy.
Journal: Vascular health and risk management 20100101
Title: Time-dependent integrity during storage of natural surface water samples for the trace analysis of pharmaceutical products, feminizing hormones and pesticides.
Journal: Chemistry Central journal 20100101
Title: PPARalpha: energy combustion, hypolipidemia, inflammation and cancer.
Journal: Nuclear receptor signaling 20100101
Title: Critical appraisal of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.
Journal: Therapeutics and clinical risk management 20100101
Title: Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosis.
Journal: BMC gastroenterology 20100101
Title: Fenofibric acid: a new fibrate approved for use in combination with statin for the treatment of mixed dyslipidemia.
Journal: Vascular health and risk management 20100101
Title: Prevention of cardiovascular disease utilizing fibrates--a pooled meta-analysis.
Journal: American journal of therapeutics 20100101
Title: Paraoxonase: Its antiatherogenic role in chronic renal failure.
Journal: Indian journal of nephrology 20100101
Title: Effects of high sucrose diet, gemfibrozil, and their combination on plasma paraoxonase 1 activity and lipid levels in rats.
Journal: Acta biochimica Polonica 20100101
Title: 'If it ain't broke, don't fix it': a commentary on the positive-negative results of the ACCORD Lipid study.
Journal: Cardiovascular diabetology 20100101
Title: The efficacy and safety of insulin-sensitizing drugs in HIV-associated lipodystrophy syndrome: a meta-analysis of randomized trials.
Journal: BMC infectious diseases 20100101
Title: Gene activation regresses atherosclerosis, promotes health, and enhances longevity.
Journal: Lipids in health and disease 20100101
Title: Use of statin therapy to reduce cardiovascular risk in older patients.
Journal: Current gerontology and geriatrics research 20100101
Title: Evidence of direct smooth muscle relaxant effects of the fibrate gemfibrozil.
Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20100101
Title: Management of dyslipidemias with fibrates, alone and in combination with statins: role of delayed-release fenofibric acid.
Journal: Vascular health and risk management 20100101
Title: Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study.
Journal: BMC gastroenterology 20100101
Title: The Role of PPARα Activation in Liver and Muscle.
Journal: PPAR research 20100101
Title: Atherogenic dyslipidemia and diabetes mellitus: what's new in the management arena?
Journal: Vascular health and risk management 20100101
Title: PPARα in Obesity: Sex Difference and Estrogen Involvement.
Journal: PPAR research 20100101
Title: Methods of chromatographic determination of medicines decreasing the level of cholesterol.
Journal: Acta poloniae pharmaceutica 20100101
Title: Peroxisome proliferator-activated receptor alpha target genes.
Journal: PPAR research 20100101
Title: The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice.
Journal: PloS one 20100101
Title: Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism.
Journal: PPAR research 20100101
Title: Drug interaction and pharmacist.
Journal: Journal of young pharmacists : JYP 20100101
Title: Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies.
Journal: Vascular health and risk management 20100101
Title: RhoA regulates peroxisome association to microtubules and the actin cytoskeleton.
Journal: PloS one 20100101
Title: Niacin or ezetimibe for patients with, or at risk of coronary heart disease.
Journal: Clinical Medicine Insights. Cardiology 20100101
Title: Lipid control and use of lipid-regulating drugs for prevention of cardiovascular events in Chinese type 2 diabetic patients: a prospective cohort study.
Journal: Cardiovascular diabetology 20100101
Title: Clinical evaluation of Dyslipidemia among type II diabetic patients at Public hospital Penang, Malaysia.
Journal: International archives of medicine 20100101
Title: Prevalence of lipid abnormalities before and after introduction of lipid modifying therapy among Swedish patients with dyslipidemia (PRIMULA).
Journal: BMC public health 20100101
Title: Low high-density lipoprotein cholesterol: current status and future strategies for management.
Journal: Vascular health and risk management 20100101
Title: Atorvastatin reduces proteinuria in non-diabetic chronic kidney disease patients partly via lowering serum levels of advanced glycation end products (AGEs).
Journal: Oxidative medicine and cellular longevity 20100101
Title: Treatment of dyslipidemia in patients with type 2 diabetes.
Journal: Lipids in health and disease 20100101
Title: High density lipoproteins-based therapies for cardiovascular disease.
Journal: Journal of cardiovascular disease research 20100101
Title: Combination of niacin extended-release and simvastatin results in a less atherogenic lipid profile than atorvastatin monotherapy.
Journal: Vascular health and risk management 20100101
Title: Uses and benefits of omega-3 ethyl esters in patients with cardiovascular disease.
Journal: Journal of multidisciplinary healthcare 20100101
Title: Two siblings with familial chylomicronemia syndrome: disease course and effectiveness of early treatment.
Journal: Case reports in medicine 20100101
Title: Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs.
Journal: PPAR research 20100101
Title: Fenofibrate treatment enhances antioxidant status and attenuates endothelial dysfunction in streptozotocin-induced diabetic rats.
Journal: Experimental diabetes research 20100101
Title: Drug-drug Interaction between Pravastatin and Gemfibrozil (Antihyperlipidemic) with Gliclazide (Antidiabetic) in Rats.
Journal: Journal of young pharmacists : JYP 20100101
Title: Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective.
Journal: Drug design, development and therapy 20100101
Title: Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment.
Journal: The open cardiovascular medicine journal 20100101
Title: Repaglinide/metformin fixed-dose combination to improve glycemic control in patients with type 2 diabetes: an update.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20100101
Title: Pitavastatin: evidence for its place in treatment of hypercholesterolemia.
Journal: Core evidence 20100101
Title: Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.
Journal: Cholesterol 20100101
Title: Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease.
Journal: Cholesterol 20100101
Title: A study of standardized extracts of Picrorhiza kurroa Royle ex Benth in experimental nonalcoholic fatty liver disease.
Journal: Journal of Ayurveda and integrative medicine 20100101
Title: Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.
Journal: Drug, healthcare and patient safety 20100101
Title: Drug interaction as cause of spontaneously resolving epidural spinal hematoma on warfarin therapy.
Journal: Journal of neurosciences in rural practice 20100101
Title: PPARs and xenobiotic-induced adverse effects: relevance to human health.
Journal: PPAR research 20100101
Title: Glucose sensing neurons in the ventromedial hypothalamus.
Journal: Sensors (Basel, Switzerland) 20100101
Title: New and emerging agents in the management of lipodystrophy in HIV-infected patients.
Journal: HIV/AIDS (Auckland, N.Z.) 20100101
Title: A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy.
Journal: Clinical pharmacology : advances and applications 20100101
Title: Occurrence of pharmaceuticals and personal care products in fish: results of a national pilot study in the United States.
Journal: Environmental toxicology and chemistry 20091201
Title: Computer-based screening of veterans for metabolic syndrome.
Journal: Metabolic syndrome and related disorders 20091201
Title: Rhabdomyolysis associated with fibrate therapy: review of 76 published cases and a new case report.
Journal: European journal of clinical pharmacology 20091201
Title: CYP2C8 activity recovers within 96 hours after gemfibrozil dosing: estimation of CYP2C8 half-life using repaglinide as an in vivo probe.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20091201
Title: Enterohepatic disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine and gemfibrozil.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20091201
Title: Gemfibrozil in late preterm and term neonates with moderate jaundice: a randomized controlled trial.
Journal: Indian pediatrics 20091201
Title: Pyranocoumarins: a new class of anti-hyperglycemic and anti-dyslipidemic agents.
Journal: Bioorganic & medicinal chemistry letters 20091115
Title: Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
Journal: Journal of medicinal chemistry 20091112
Title: Novel LMF1 nonsense mutation in a patient with severe hypertriglyceridemia.
Journal: The Journal of clinical endocrinology and metabolism 20091101
Title: Triglycerides and HDL cholesterol: stars or second leads in diabetes?
Journal: Diabetes care 20091101
Title: Impact of chronic anticholesterol therapy on development of microvascular rarefaction in the metabolic syndrome.
Journal: Microcirculation (New York, N.Y. : 1994) 20091101
Title: A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.
Journal: Environmental health perspectives 20091101
Title: Design, synthesis and hypolipidemic activity of novel 2-(naphthalen-2-yloxy)propionic acid derivatives as desmethyl fibrate analogs.
Journal: European journal of medicinal chemistry 20091001
Title: Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20091001
Title: Gemfibrozil concentrations are significantly decreased in the presence of lopinavir-ritonavir.
Journal: Journal of acquired immune deficiency syndromes (1999) 20091001
Title: Effect of fibrates on lipid profiles and cardiovascular outcomes: a systematic review.
Journal: The American journal of medicine 20091001
Title: [Place of fibrates for the treatment of patients with atherogenic dyslipidemia].
Journal: Revue medicale de Liege 20091001
Title: Probing the fibrate binding specificity of rat liver fatty acid binding protein.
Journal: Journal of medicinal chemistry 20090910
Title: AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons.
Journal: American journal of physiology. Cell physiology 20090901
Title: The mechanism and mitigation of niacin-induced flushing.
Journal: International journal of clinical practice 20090901
Title: Positive relationship between dietary fat, ethanol intake, triglycerides, and hypothalamic peptides: counteraction by lipid-lowering drugs.
Journal: Alcohol (Fayetteville, N.Y.) 20090901
Title: On the mechanism for PPAR agonists to enhance ABCA1 gene expression.
Journal: Atherosclerosis 20090801
Title: Pleiotropic action of short-term metformin and fenofibrate treatment, combined with lifestyle intervention, in type 2 diabetic patients with mixed dyslipidemia.
Journal: Diabetes care 20090801
Title: Runoff of pharmaceuticals and personal care products following application of dewatered municipal biosolids to an agricultural field.
Journal: The Science of the total environment 20090801
Title: Apolipoprotein B but not LDL cholesterol is associated with coronary artery calcification in type 2 diabetic whites.
Journal: Diabetes 20090801
Title: Automated zone-sampling dilution by coupling sequential injection analysis to high-throughput HPLC for the direct determination of gemfibrozil.
Journal: Journal of separation science 20090801
Title: Recovery time in a case of gemfibrozil and simvastatin-associated rhabdomyolysis.
Journal: Southern medical journal 20090801
Title: Occurrence and removal of pharmaceutically active compounds in sewage treatment plants with different technologies.
Journal: Journal of environmental monitoring : JEM 20090801
Title: Effects of gemfibrozil on outcome after permanent middle cerebral artery occlusion in mice.
Journal: Brain research 20090707
Title: Estrogenic activity of pharmaceuticals in the aquatic environment.
Journal: Environment international 20090701
Title: High-performance liquid chromatography method for determination of carnosic acid in rat plasma and its application to pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20090701
Title: Clomiphene citrate-induced severe hypertriglyceridemia.
Journal: Fertility and sterility 20090701
Title: Pharmaceutical and personal care products in tile drainage following surface spreading and injection of dewatered municipal biosolids to an agricultural field.
Journal: The Science of the total environment 20090701
Title: Benzylic oxidation of gemfibrozil-1-O-beta-glucuronide by P450 2C8 leads to heme alkylation and irreversible inhibition.
Journal: Chemical research in toxicology 20090701
Title: A randomized placebo-controlled study on the effect of nifedipine on coronary endothelial function and plaque formation in patients with coronary artery disease: the ENCORE II study.
Journal: European heart journal 20090701
Title: Effects of WY-14643 on peroxisomal enzyme activity and hormone secretion in immortalized human trophoblast cells.
Journal: Biological & pharmaceutical bulletin 20090701
Title: Elevated creatine phosphokinase levels associated with linezolid therapy.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090615
Title: Design, synthesis and hypolipidemic activity of novel 2-(m-tolyloxy) isobutyric acid derivatives.
Journal: European journal of medicinal chemistry 20090601
Title: Effects of rosuvastatin and atorvastatin on LDL and HDL particle concentrations in patients with metabolic syndrome: a randomized, double-blind, controlled study.
Journal: Diabetes care 20090601
Title: Identification of the efflux transporter of the fluoroquinolone antibiotic ciprofloxacin in murine macrophages: studies with ciprofloxacin-resistant cells.
Journal: Antimicrobial agents and chemotherapy 20090601
Title: Occurrence of pharmaceuticals in Taiwan's surface waters: impact of waste streams from hospitals and pharmaceutical production facilities.
Journal: The Science of the total environment 20090601
Title: Rapid oxidation of ring methyl groups is the primary mechanism of biotransformation of gemfibrozil by the fungus Cunninghamella elegans.
Journal: Archives of microbiology 20090601
Title: Interaction between gemfibrozil and warfarin: case report and review of the literature.
Journal: Pharmacotherapy 20090601
Title: Inhibition by fibrates of plasminogen activator inhibitor type-1 expression in human adipocytes and preadipocytes.
Journal: Thrombosis and haemostasis 20090601
Title: Hypertriglyceridaemia-induced acute pancreatitis due to patient non-compliance.
Journal: Journal of clinical pharmacy and therapeutics 20090601
Title: Omega-3 ethylester concentrate: a review of its use in secondary prevention post-myocardial infarction and the treatment of hypertriglyceridaemia.
Journal: Drugs 20090529
Title: Human health risk assessment for peroxisome proliferators: more than 30 years of research.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090501
Title: Efficacy of gemfibrozil in the primary prevention of atrial fibrillation in a large randomized controlled trial.
Journal: American heart journal 20090501
Title: Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer.
Journal: Current oncology (Toronto, Ont.) 20090501
Title: Antidyslipidemic and antioxidative activities of 8-hydroxyquinoline derived novel keto-enamine Schiffs bases.
Journal: European journal of medicinal chemistry 20090401
Title: Antidiabetic action of bezafibrate in a large observational database.
Journal: Diabetes care 20090401
Title: Transcriptional modulation of the immune response by peroxisome proliferator-activated receptor-{alpha} agonists in autoimmune disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20090401
Title: Gene expression profiling in rat liver treated with compounds inducing elevation of bilirubin.
Journal: Human & experimental toxicology 20090401
Title: Flushing and other dermatologic adverse events associated with extended-release niacin therapy.
Journal: Journal of clinical lipidology 20090401
Title: Hypertriglyceridemia and its pharmacologic treatment among US adults.
Journal: Archives of internal medicine 20090323
Title: Myotoxicity of gemfibrozil in cynomolgus monkey model and its relationship to pharmacokinetic properties.
Journal: Toxicology and applied pharmacology 20090315
Title: Summaries for patients. Response to cholesterol-lowering drugs in patients with and without HIV infection.
Journal: Annals of internal medicine 20090303
Title: Response to newly prescribed lipid-lowering therapy in patients with and without HIV infection.
Journal: Annals of internal medicine 20090303
Title: Determination of pharmaceuticals in sewage sludge by pressurized liquid extraction (PLE) coupled to liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Journal: Analytical and bioanalytical chemistry 20090301
Title: A high performance liquid chromatography method for simultaneous determination of rosiglitazone and gemfibrozil in human plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090301
Title: Meeting the challenge of influenza pandemic preparedness in developing countries.
Journal: Emerging infectious diseases 20090301
Title: Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway.
Journal: PLoS pathogens 20090301
Title: Lipid lowering activity of ethanolic extract of leaves of Aegle marmelos (Linn.) in hyperlipidaemic models of Wistar albino rats.
Journal: Indian journal of experimental biology 20090301
Title: Free-radical-induced oxidative and reductive degradation of fibrate pharmaceuticals: kinetic studies and degradation mechanisms.
Journal: The journal of physical chemistry. A 20090219
Title: Combination statin-fibrate therapy: safety aspects.
Journal: Diabetes, obesity & metabolism 20090201
Title: Effects of high-dose simvastatin therapy on glucose metabolism and ectopic lipid deposition in nonobese type 2 diabetic patients.
Journal: Diabetes care 20090201
Title: The influence of natural organic matter and cations on the rejection of endocrine disrupting and pharmaceutically active compounds by nanofiltration.
Journal: Water research 20090201
Title: Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment.
Journal: Water research 20090201
Title: Fibrates: where are we now?
Journal: Therapeutic advances in cardiovascular disease 20090201
Title: Effect of combination nicotinic acid and gemfibrozil treatment on intermediate density lipoprotein, and subclasses of low density lipoprotein and high density lipoprotein in patients with combined hyperlipidemia.
Journal: The American journal of cardiology 20090201
Title: Effects of diet and gemfibrozil on posttransplant hyperlipidemia in renal transplant recipients.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20090201
Title: Increase in tiagabine serum concentration with coadministration of gemfibrozil.
Journal: The Annals of pharmacotherapy 20090201
Title: Pharmaceuticals and endocrine disrupting compounds in U.S. drinking water.
Journal: Environmental science & technology 20090201
Title: Evaluation of the acute, chronic and teratogenic effects of a mixture of eleven pharmaceuticals on the cnidarian, Hydra attenuata.
Journal: The Science of the total environment 20090115
Title: Syntheses and evaluation of glucosyl aryl thiosemicarbazide and glucosyl thiosemicarbazone derivatives as antioxidant and anti-dyslipidemic agents.
Journal: Bioorganic & medicinal chemistry letters 20090115
Title: Prediction of drug clearance by glucuronidation from in vitro data: use of combined cytochrome P450 and UDP-glucuronosyltransferase cofactors in alamethicin-activated human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090101
Title: Determination of phenolic endocrine disrupting chemicals and acidic pharmaceuticals in surface water of the Pearl Rivers in South China by gas chromatography-negative chemical ionization-mass spectrometry.
Journal: The Science of the total environment 20090101
Title: Does nicotinic acid (niacin) lower blood pressure?
Journal: International journal of clinical practice 20090101
Title: Prevention and treatment of atherosclerosis: a practitioner's guide for 2008.
Journal: The American journal of medicine 20090101
Title: Standards of medical care in diabetes--2009.
Journal: Diabetes care 20090101
Title: Multiple splice defects in ABCA1 cause low HDL-C in a family with hypoalphalipoproteinemia and premature coronary disease.
Journal: BMC medical genetics 20090101
Title: Augmented lung inflammation protects against influenza A pneumonia.
Journal: PloS one 20090101
Title: Pharmspresso: a text mining tool for extraction of pharmacogenomic concepts and relationships from full text.
Journal: BMC bioinformatics 20090101
Title: Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis.
Journal: BMJ (Clinical research ed.) 20090101
Title: Life-cycle exposure of fathead minnows to a mixture of six common pharmaceuticals and triclosan.
Journal: Journal of toxicology and environmental health. Part A 20090101
Title: MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-γ agonist lowers triglyceride independently of PPAR-α activation.
Journal: PPAR research 20090101
Title: Efficacy and safety of rosuvastatin in the management of dyslipidemia.
Journal: Vascular health and risk management 20090101
Title: Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin.
Journal: Vascular health and risk management 20090101
Title: Dyslipidemia treatment of patients with diabetes mellitus in a US managed care plan: a retrospective database analysis.
Journal: Cardiovascular diabetology 20090101
Title: Safety and efficacy of rosiglitazone in the elderly diabetic patient.
Journal: Vascular health and risk management 20090101
Title: Lactic acid bacteria affect serum cholesterol levels, harmful fecal enzyme activity, and fecal water content.
Journal: Lipids in health and disease 20090101
Title: [Fibrate-induced deterioration of renal function].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101
Title: Effects of cardiovascular lifestyle change on lipoprotein subclass profiles defined by nuclear magnetic resonance spectroscopy.
Journal: Lipids in health and disease 20090101
Title: Kidney function and estimated vascular risk in patients with primary dyslipidemia.
Journal: The open cardiovascular medicine journal 20090101
Title: Regulation of bile acid and cholesterol metabolism by PPARs.
Journal: PPAR research 20090101
Title: New options in the treatment of lipid disorders in HIV-infected patients.
Journal: The open AIDS journal 20090101
Title: Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.
Journal: PPAR research 20090101
Title: Gemfibrozil, stretching arms beyond lipid lowering.
Journal: Immunopharmacology and immunotoxicology 20090101
Title: Peroxisome proliferator-activated receptor agonists: do they increase cardiovascular risk?
Journal: PPAR research 20090101
Title: Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention.
Journal: Vascular health and risk management 20090101
Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.
Journal: PloS one 20090101
Title: Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk.
Journal: Vascular health and risk management 20090101
Title: Post-transplant diabetes mellitus.
Journal: Diabetology & metabolic syndrome 20090101
Title: A 60-year-old man with chronic renal failure and a costal mass: a case report and review of the literature.
Journal: Journal of medical case reports 20090101
Title: Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.
Journal: BMC medical genetics 20090101
Title: Serum and erythrocyte membrane phospholipids fatty acid composition in hyperlipidemia: effects of dietary intervention and combined diet and fibrate therapy.
Journal: General physiology and biophysics 20090101
Title: Plasmapheresis in a patient with rhabdomyolysis: a case report.
Journal: Cases journal 20090101
Title: Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver.
Journal: Lipids in health and disease 20090101
Title: Treatment of hypertriglyceridemia and HIV: fenofibrate-induced changes in the expression of chemokine genes in circulating leukocytes.
Journal: AIDS research and therapy 20090101
Title: Membrane omega-3 Fatty Acid deficiency as a preventable risk factor for comorbid coronary heart disease in major depressive disorder.
Journal: Cardiovascular psychiatry and neurology 20090101
Title: Management of dyslipidemia in children.
Journal: Diabetology & metabolic syndrome 20090101
Title: Critical appraisal of the role of pitavastatin in treating dyslipidemias and achieving lipid goals.
Journal: Vascular health and risk management 20090101
Title: Pharmacokinetic Study of a Novel Antihyperlipidemic Agent LM-13765- A Prodrug.
Journal: Indian journal of pharmaceutical sciences 20090101
Title: Raising HDL cholesterol in women.
Journal: International journal of women's health 20090101
Title: Alogliptin: a new addition to the class of DPP-4 inhibitors.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20090101
Title: Expert perspective: reducing cardiovascular risk in metabolic syndrome and type 2 diabetes mellitus beyond low-density lipoprotein cholesterol lowering.
Journal: The American journal of cardiology 20081222
Title: Severe acute renal failure following high-dose methotrexate therapy in adults with haematological malignancies: a significant number result from unrecognized co-administration of several drugs.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201
Title: Novel peroxisome proliferator-activated receptor alpha agonists lower low-density lipoprotein and triglycerides, raise high-density lipoprotein, and synergistically increase cholesterol excretion with a liver X receptor agonist.
Journal: The Journal of pharmacology and experimental therapeutics 20081201
Title: Diplopia, blepharoptosis, and ophthalmoplegia and 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitor use.
Journal: Ophthalmology 20081201
Title: Determination of pharmaceuticals in drinking water by CD-modified MEKC: separation optimization using experimental design.
Journal: Journal of separation science 20081201
Title: Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome.
Journal: Biologics : targets & therapy 20081201
Title: Rosuvastatin reduces non-high-density lipoprotein cholesterol and lipoprotein remnants in patients with dysbetalipoproteinemia (Fredrickson type III hyperlipoproteinemia).
Journal: Journal of clinical lipidology 20081201
Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Journal: Journal of medicinal chemistry 20081113
Title: Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents.
Journal: European journal of medicinal chemistry 20081101
Title: Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
Journal: Journal of chromatography. A 20081031
Title: Design, synthesis, and biological evaluation of novel constrained meta-substituted phenyl propanoic acids as peroxisome proliferator-activated receptor alpha and gamma dual agonists.
Journal: Journal of medicinal chemistry 20081023
Title: To statin or to non-statin in coronary disease-considering absolute risk is the answer.
Journal: Atherosclerosis 20081001
Title: Correlation between plasma levels of 7alpha-hydroxy-4-cholesten-3-one and cholesterol 7alpha-hydroxylation rates in vivo in hyperlipidemic patients.
Journal: Steroids 20081001
Title: Triglycerides and risk for coronary artery disease.
Journal: Current atherosclerosis reports 20081001
Title: Biodegradation of acidic pharmaceuticals in bed sediments: insight from a laboratory experiment.
Journal: Environmental science & technology 20081001
Title: Update on the clinical utility of fenofibrate in mixed dyslipidemias: mechanisms of action and rational prescribing.
Journal: Vascular health and risk management 20081001
Title: Targeting multiple dyslipidemias with fixed combinations--focus on extended release niacin and simvastatin.
Journal: Vascular health and risk management 20081001
Title: Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism.
Journal: Clinical pharmacology and therapeutics 20081001
Title: The effect of gemfibrozil on repaglinide pharmacokinetics persists for at least 12 h after the dose: evidence for mechanism-based inhibition of CYP2C8 in vivo.
Journal: Clinical pharmacology and therapeutics 20080901
Title: Application of software design principles and debugging methods to an analgesia prescription reduces risk of severe injury from medical use of opioids.
Journal: Clinical pharmacology and therapeutics 20080901
Title: Confronting an influenza pandemic with inexpensive generic agents: can it be done?
Journal: The Lancet. Infectious diseases 20080901
Title: Investigation on different levels of in vitro-in vivo correlation: gemfibrozil immediate release capsule.
Journal: Biopharmaceutics & drug disposition 20080901
Title: The effects of pharmaceuticals on the regeneration of the cnidarian, Hydra attenuata.
Journal: The Science of the total environment 20080825
Title: A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats.
Journal: Toxicology 20080819
Title: Efficacy and safety of a potent and selective peroxisome proliferator activated receptor alpha agonist in subjects with dyslipidemia and type 2 diabetes mellitus.
Journal: The American journal of cardiology 20080815
Title: Micronization of gemfibrozil by reactive precipitation process.
Journal: International journal of pharmaceutics 20080806
Title: Analysis of the complexation of gemfibrozil with gamma- and hydroxypropyl-gamma-cyclodextrins.
Journal: Journal of pharmaceutical and biomedical analysis 20080805
Title: Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit.
Journal: Cardiovascular drugs and therapy 20080801
Title: Rejection of pharmaceuticals in nanofiltration and reverse osmosis membrane drinking water treatment.
Journal: Water research 20080801
Title: Genomic profiling reveals an alternate mechanism for hepatic tumor promotion by perfluorooctanoic acid in rainbow trout.
Journal: Environmental health perspectives 20080801
Title: Familial dysbetalipoproteinemia: a potentially fatal disorder.
Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20080801
Title: The Relationship Between HIV Infection and Cardiovascular Disease.
Journal: Current cardiology reviews 20080801
Title: Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Journal: Journal of medicinal chemistry 20080710
Title: An unusual case of familial hyperlipidaemia.
Journal: Indian journal of clinical biochemistry : IJCB 20080701
Title: The occurrence of acidic drugs and caffeine in sewage effluents and receiving waters from three coastal watersheds in Atlantic Canada.
Journal: The Science of the total environment 20080625
Title: Runoff of pharmaceuticals and personal care products following application of biosolids to an agricultural field.
Journal: The Science of the total environment 20080615
Title: Cardiovascular events with increased lipoprotein-associated phospholipase A(2) and low high-density lipoprotein-cholesterol: the Veterans Affairs HDL Intervention Trial.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080601
Title: Use of biodegradable dissolved organic carbon (BDOC) to assess the potential for transformation of wastewater-derived contaminants in surface waters.
Journal: Water research 20080601
Title: Efficacy of lipid-lowering medications in patients treated with clozapine: a naturalistic study.
Journal: Journal of clinical psychopharmacology 20080601
Title: Mortality in COPD: inevitable or preventable? Insights from the cardiovascular arena.
Journal: COPD 20080601
Title: In vitro evaluation of reversible and irreversible cytochrome P450 inhibition: current status on methodologies and their utility for predicting drug-drug interactions.
Journal: The AAPS journal 20080601
Title: Atorvastatin and cardiovascular risk in the elderly--patient considerations.
Journal: Clinical interventions in aging 20080601
Title: Relative safety profiles of high dose statin regimens.
Journal: Vascular health and risk management 20080601
Title: Multiple inhibition mechanisms and prediction of drug-drug interactions: status of metabolism and transporter models as exemplified by gemfibrozil-drug interactions.
Journal: Pharmaceutical research 20080501
Title: Pharmaceutical particle engineering via spray drying.
Journal: Pharmaceutical research 20080501
Title: The excitation-contraction coupling on C2C12 skeletal muscle myotubes was modulated by NO-donor ester of gemfibrozil.
Journal: Nitric oxide : biology and chemistry 20080501
Title: Obesity and hypertriglyceridemia produce cognitive impairment.
Journal: Endocrinology 20080501
Title: Clofibrate and gemfibrozil induce an embryonic malabsorption syndrome in zebrafish.
Journal: Toxicology and applied pharmacology 20080501
Title: Effectiveness of lipid-lowering therapy in HIV patients.
Journal: Current opinion in HIV and AIDS 20080501
Title: Inhibiting wild-type and C299S mutant AKR1B10; a homologue of aldose reductase upregulated in cancers.
Journal: European journal of pharmacology 20080428
Title: Fate of pharmaceutical and trace organic compounds in three septic system plumes, Ontario, Canada.
Journal: Environmental science & technology 20080415
Title: Concentrations and mobility of human pharmaceuticals in the world's largest wastewater irrigation system, Mexico City-Mezquital Valley.
Journal: Water research 20080401
Title: Differential effects of fibrates on the metabolic activation of 2-phenylpropionic acid in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080401
Title: The peroxisome: still a mysterious organelle.
Journal: Histochemistry and cell biology 20080401
Title: Belgian expert opinion: how to reduce the residual risk in atherogenic dyslipidaemic patients: place of fibrates.
Journal: Acta cardiologica 20080401
Title: Combination therapy in cholesterol reduction: focus on ezetimibe and statins.
Journal: Vascular health and risk management 20080401
Title: Clinical efficacy and safety of statins in managing cardiovascular risk.
Journal: Vascular health and risk management 20080401
Title: A pilot study in the efficacy and safety of gemfibrozil in a pediatric population.
Journal: Journal of clinical lipidology 20080401
Title: Effects of fibrate drugs on expression of ABCA1 and HDL biogenesis in hepatocytes.
Journal: Journal of cardiovascular pharmacology 20080301
Title: [Prescription patterns for antilipidemic drugs in a group of Colombian patients].
Journal: Revista panamericana de salud publica = Pan American journal of public health 20080301
Title: Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates.
Journal: International journal of cardiology 20080227
Title: Phytotoxicity evaluation of five pharmaceutical pollutants detected in surface water on germination and growth of cultivated and spontaneous plants.
Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20080215
Title: Body weight, plasma insulin, and coronary events with gemfibrozil in the Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT).
Journal: Atherosclerosis 20080201
Title: The effect of suspended particles coated by humic acid on the toxicity of pharmaceuticals, estrogens, and phenolic compounds.
Journal: Environment international 20080201
Title: The economic consequences of noncompliance in cardiovascular disease and related conditions: a literature review.
Journal: International journal of clinical practice 20080201
Title: Management of mixed dyslipidemia in patients with or at risk for cardiovascular disease: a role for combination fibrate therapy.
Journal: Clinical therapeutics 20080201
Title: Does the addition of fibrates to statin therapy have a favorable risk to benefit ratio?
Journal: Current atherosclerosis reports 20080201
Title: Update on the use of fibrates: focus on bezafibrate.
Journal: Vascular health and risk management 20080201
Title: High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease.
Journal: Vascular health and risk management 20080201
Title: A hazardous finding of a rare anomalous left main coronary artery in a patient with a secundum atrial septal defect.
Journal: Vascular health and risk management 20080201
Title: An investigation into the acute and chronic toxicity of eleven pharmaceuticals (and their solvents) found in wastewater effluent on the cnidarian, Hydra attenuata.
Journal: The Science of the total environment 20080125
Title: Influence of gemfibrozil on sulfate transport in human erythrocytes during the oxygenation-deoxygenation cycle.
Journal: Physiological research 20080101
Title: Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome?
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080101
Title: Peroxisome proliferator-activated receptors--from active regulators of macrophage biology to pharmacological targets in the treatment of cardiovascular disease.
Journal: Journal of internal medicine 20080101
Title: Relation of gemfibrozil treatment and high-density lipoprotein subpopulation profile with cardiovascular events in the Veterans Affairs High-Density Lipoprotein Intervention Trial.
Journal: Metabolism: clinical and experimental 20080101
Title: Peroxisome proliferator-activated receptors (PPARs) and the human skin: importance of PPARs in skin physiology and dermatologic diseases.
Journal: American journal of clinical dermatology 20080101
Title: Relative safety of gemfibrozil and fenofibrate in the absence of concomitant cerivastatin use.
Journal: The American journal of cardiology 20080101
Title: Incidence of adverse events with HMG-CoA reductase inhibitors in liver transplant patients.
Journal: Clinical transplantation 20080101
Title: Effect of chemosensitizers on minimum inhibitory concentrations of fluconazole in Candida albicans.
Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20080101
Title: Peroxisome proliferator activated receptors and lipoprotein metabolism.
Journal: PPAR research 20080101
Title: PPAR Agonists and Cardiovascular Disease in Diabetes.
Journal: PPAR research 20080101
Title: The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects.
Journal: PPAR research 20080101
Title: Should We Use PPAR Agonists to Reduce Cardiovascular Risk?
Journal: PPAR research 20080101
Title: Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.
Journal: PloS one 20080101
Title: Frequency and clinical relevance of drug interactions with lovastatin and simvastatin: an observational database study.
Journal: Drug safety 20080101
Title: Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT.
Journal: AIDS research and therapy 20080101
Title: PPAR-gamma, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches.
Journal: PPAR research 20080101
Title: PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease.
Journal: PPAR research 20080101
Title: PPAR-alpha Ligands as Potential Therapeutic Agents for Wet Age-Related Macular Degeneration.
Journal: PPAR research 20080101
Title: PPARs and Female Reproduction: Evidence from Genetically Manipulated Mice.
Journal: PPAR research 20080101
Title: Hypertriglyceridemia and hypercholesterolemia: effects of drug treatment on fatty acid composition of plasma lipids and membranes.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080101
Title: Plasma PCSK9 levels are significantly modified by statins and fibrates in humans.
Journal: Lipids in health and disease 20080101
Title: Peroxisome proliferator-activated receptors and progression of colorectal cancer.
Journal: PPAR research 20080101
Title: Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin.
Journal: Clinical pharmacokinetics 20080101
Title: Peroxisome Proliferators-Activated Receptor (PPAR) Modulators and Metabolic Disorders.
Journal: PPAR research 20080101
Title: Statin induced myopathy and myalgia: time trend analysis and comparison of risk associated with statin class from 1991-2006.
Journal: PloS one 20080101
Title: [Rosuvastatin for the treatment of dyslipidemia in HIV-infected patients receiving highly active antiretroviral therapy. Preliminary experience].
Journal: Enfermedades infecciosas y microbiologia clinica 20080101
Title: Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
Journal: PPAR research 20080101
Title: PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis.
Journal: PPAR research 20080101
Title: PPAR Ligands as Potential Modifiers of Breast Carcinoma Outcomes.
Journal: PPAR research 20080101
Title: Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.
Journal: PPAR research 20080101
Title: PPAR Regulation of Inflammatory Signaling in CNS Diseases.
Journal: PPAR research 20080101
Title: PPARalpha Ligands as Antitumorigenic and Antiangiogenic Agents.
Journal: PPAR research 20080101
Title: Pioglitazone versus Rosiglitazone: Effects on Lipids, Lipoproteins, and Apolipoproteins in Head-to-Head Randomized Clinical Studies.
Journal: PPAR research 20080101
Title: Oxidative effects of gemfibrozil on anion influx and metabolism in normal and Beta-thalassemic erythrocytes: physiological implications.
Journal: The Journal of membrane biology 20080101
Title: Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20080101
Title: Low HDL cholesterol, smoking and IL-13 R130Q polymorphism are associated with myocardial infarction in Greek Cypriot males. A pilot study.
Journal: The open cardiovascular medicine journal 20080101
Title: Statins but not fibrates improve the atherogenic to anti-atherogenic lipoprotein particle ratio: a randomized crossover study.
Journal: BMC clinical pharmacology 20080101
Title: Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians.
Journal: Environmental health : a global access science source 20080101
Title: PPAR-delta in Vascular Pathophysiology.
Journal: PPAR research 20080101
Title: Preformulative assessment of preformed complexes of gemfibrozil, with cyclodextrins.
Journal: PDA journal of pharmaceutical science and technology 20080101
Title: The Role of NF-kappaB in PPARalpha-Mediated Hepatocarcinogenesis.
Journal: PPAR research 20080101
Title: Peroxisome proliferator-activated receptors in diabetic nephropathy.
Journal: PPAR research 20080101
Title: Effect of Chlorella vulgaris on lipid metabolism in Wistar rats fed high fat diet.
Journal: Nutrition research and practice 20080101
Title: Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.
Journal: The Journal of biological chemistry 20071214
Title: How useful are prescribing indicators based on the DU90% method to distinguish the quality of prescribing between pharmacotherapy audit meetings with different levels of functioning?
Journal: European journal of clinical pharmacology 20071201
Title: Fenofibrate inhibits intestinal Cl- secretion by blocking basolateral KCNQ1 K+ channels.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20071201
Title: Gemfibrozil ingestions reported to Texas poison control centers, 2000-2005.
Journal: Journal of toxicology and environmental health. Part A 20071201
Title: Prediction of the metabolic interaction of nateglinide with other drugs based on in vitro studies.
Journal: Drug metabolism and pharmacokinetics 20071201
Title: Practical guidelines for familial combined hyperlipidemia diagnosis: an up-date.
Journal: Vascular health and risk management 20071201
Title: Shift work, occupational noise and physical workload with ensuing development of blood pressure and their joint effect on the risk of coronary heart disease.
Journal: Scandinavian journal of work, environment & health 20071201
Title: Treatment of non-alcoholic fatty liver disease.
Journal: Therapeutics and clinical risk management 20071201
Title: Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin.
Journal: The Journal of biological chemistry 20071102
Title: To statin or to non-statin in coronary disease--considering absolute risk is the answer.
Journal: Atherosclerosis 20071101
Title: Increased atherosclerosis following treatment with a dual PPAR agonist in the ApoE knockout mouse.
Journal: Atherosclerosis 20071101
Title: The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071101
Title: Variations in bioconcentration of human pharmaceuticals from sewage effluents into fish blood plasma.
Journal: Environmental toxicology and pharmacology 20071101
Title: Risk of congenital anomalies in pregnant users of statin drugs.
Journal: British journal of clinical pharmacology 20071001
Title: Effects of blood lipid lowering pharmaceuticals (bezafibrate and gemfibrozil) on immune and digestive gland functions of the bivalve mollusc, Mytilus galloprovincialis.
Journal: Chemosphere 20071001
Title: Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha.
Journal: Molecular pharmacology 20071001
Title: Gene expression profiling of rat liver treated with serum triglyceride-decreasing compounds.
Journal: The Journal of toxicological sciences 20071001
Title: Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors.
Journal: Vascular health and risk management 20071001
Title: Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration.
Journal: Toxicology and applied pharmacology 20070915
Title: Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070915
Title: Codon 54 polymorphism of the fatty acid binding protein (FABP) 2 gene is associated with increased cardiovascular risk in the dyslipidemic diabetic participants of the Veterans Affairs HDL intervention trial (VA-HIT).
Journal: Atherosclerosis 20070901
Title: Simvastatin: present and future perspectives.
Journal: Expert opinion on pharmacotherapy 20070901
Title: The clinical relevance of LDL size and subclasses modulation in patients with type-2 diabetes.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070901
Title: Use of lipid-modulating drugs in complicated course of coronary heart disease.
Journal: Bulletin of experimental biology and medicine 20070901
Title: Cheaper approaches to flu divide researchers.
Journal: Nature 20070830
Title: Endothelial NF-kappaB as a mediator of kidney damage: the missing link between systemic vascular and renal disease?
Journal: Circulation research 20070803
Title: Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801
Title: Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801
Title: Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI.
Journal: Journal of lipid research 20070801
Title: Wastewater treatment plants as a pathway for aquatic contamination by pharmaceuticals in the ebro river basin (northeast Spain).
Journal: Environmental toxicology and chemistry 20070801
Title: Prolonged-release nicotinic acid for the management of dyslipidemia: an update including results from the NAUTILUS study.
Journal: Vascular health and risk management 20070801
Title: Mitochondria, ciglitazone and liver: a neglected interaction in biochemical pharmacology.
Journal: European journal of pharmacology 20070712
Title: Toxic and genotoxic impact of fibrates and their photoproducts on non-target organisms.
Journal: Environment international 20070701
Title: Expeditious and convenient synthesis of pregnanes and its glycosides as potential anti-dyslipidemic and anti-oxidant agents.
Journal: Bioorganic & medicinal chemistry 20070701
Title: Design, synthesis, and structure-activity relationship of carbamate-tethered aryl propanoic acids as novel PPARalpha/gamma dual agonists.
Journal: Bioorganic & medicinal chemistry letters 20070701
Title: Electrokinetic migration of acidic drugs across a supported liquid membrane.
Journal: Journal of chromatography. A 20070608
Title: Analytical development for analysis of pharmaceuticals in water samples by SPE and GC-MS.
Journal: Analytical and bioanalytical chemistry 20070601
Title: A randomized trial of the effect of statin and fibrate therapy on arterial function in CKD.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20070601
Title: [High sensitivity of C-reactive protein in primary prevention].
Journal: Giornale italiano di cardiologia (2006) 20070601
Title: Stereoselective interaction between the CYP2C8 inhibitor gemfibrozil and racemic ibuprofen.
Journal: European journal of clinical pharmacology 20070501
Title: The clinical significance of the size of low-density-lipoproteins and the modulation of subclasses by fibrates.
Journal: Current medical research and opinion 20070501
Title: Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070501
Title: Cholesterol reduction yields clinical benefits: meta-analysis including recent trials.
Journal: Clinical therapeutics 20070501
Title: Optimizing gas chromatographic-mass spectrometric analysis of selected pharmaceuticals and endocrine-disrupting substances in water using factorial experimental design.
Journal: Journal of chromatography. A 20070427
Title: Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070401
Title: Safety considerations with fibrate therapy.
Journal: The American journal of cardiology 20070319
Title: Risk factors for statin-associated rhabdomyolysis.
Journal: Pharmacoepidemiology and drug safety 20070301
Title: PPAR alpha agonists improve renal preservation in kidneys subjected to chronic in vitro perfusion: interaction with mannitol.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070301
Title: Fibrates: what have we learned in the past 40 years?
Journal: Pharmacotherapy 20070301
Title: Neuropsychiatric consequences of cardiovascular medications.
Journal: Dialogues in clinical neuroscience 20070301
Title: Effect of drugs on high-density lipoprotein.
Journal: Journal of clinical lipidology 20070301
Title: Toxicological effects of the lipid regulator gemfibrozil in four aquatic systems.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070215
Title: Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor.
Journal: Analytical and bioanalytical chemistry 20070201
Title: Polar herbicides, pharmaceutical products, perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and nonylphenol and its carboxylates and ethoxylates in surface and tap waters around Lake Maggiore in Northern Italy.
Journal: Analytical and bioanalytical chemistry 20070201
Title: Tamoxifen and hypertriglyceridaemia.
Journal: Prescrire international 20070201
Title: Human pharmaceuticals, antioxidants, and plasticizers in wastewater treatment plant and water reclamation plant effluents.
Journal: Water environment research : a research publication of the Water Environment Federation 20070201
Title: Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels.
Journal: Vascular health and risk management 20070201
Title: Vascular wall proteoglycan synthesis and structure as a target for the prevention of atherosclerosis.
Journal: Vascular health and risk management 20070201
Title: Chylous ascites secondary to hyperlipidemic pancreatitis with normal serum amylase and lipase.
Journal: World journal of gastroenterology 20070121
Title: A simple in vitro model to study the stability of acylglucuronides.
Journal: Journal of pharmacological and toxicological methods 20070101
Title: Effect of a mixture of seven pharmaceuticals on Hyalella azteca over multiple generations.
Journal: Chemosphere 20070101
Title: Therapeutic approach to FSGS in children.
Journal: Pediatric nephrology (Berlin, Germany) 20070101
Title: Combined organ failure with combination antihyperlipidemic treatment: a case of hepatic injury and acute renal failure.
Journal: The Annals of pharmacotherapy 20070101
Title: Pharmacokinetic interactions with thiazolidinediones.
Journal: Clinical pharmacokinetics 20070101
Title: Drug-drug and food-drug pharmacokinetic interactions with new insulinotropic agents repaglinide and nateglinide.
Journal: Clinical pharmacokinetics 20070101
Title: Safety of rosuvastatin: update on 16,876 rosuvastatin-treated patients in a multinational clinical trial program.
Journal: Cardiology 20070101
Title: Use of statins and gemfibrozil in patients with type 2 diabetes mellitus and cardiovascular risk factors attending adult day health care centers: an opportunity for pharmacists.
Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20070101
Title: PPARs, Obesity, and Inflammation.
Journal: PPAR research 20070101
Title: Risk and predictability of drug interactions in the elderly.
Journal: International review of neurobiology 20070101
Title: Therapeutic potential of retinoid x receptor modulators for the treatment of the metabolic syndrome.
Journal: PPAR research 20070101
Title: Therapeutic rationale of combining therapy with gemfibrozil and simvastatin.
Journal: Journal of the American Pharmacists Association : JAPhA 20070101
Title: Pharmacokinetic comparisons of tail-bleeding with cannula- or retro-orbital bleeding techniques in rats using six marketed drugs.
Journal: Journal of pharmacological and toxicological methods 20070101
Title: Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report.
Journal: Journal of medical case reports 20070101
Title: HIV-associated adipose redistribution syndrome (HARS): definition, epidemiology and clinical impact.
Journal: AIDS research and therapy 20070101
Title: Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes.
Journal: Cardiovascular diabetology 20070101
Title: The Role of PPARs in Lung Fibrosis.
Journal: PPAR research 20070101
Title: An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study.
Journal: BMC genetics 20070101
Title: PPARs and diabetes-associated atherosclerosis.
Journal: Current pharmaceutical design 20070101
Title: Are HIV positive patients resistant to statin therapy?
Journal: Lipids in health and disease 20070101
Title: Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects.
Journal: Lipids in health and disease 20070101
Title: Synthesis and antihyperlipidemic activity of some novel condensed 2-chloroalkyl-4-chloro/hydroxy-5,6-disubstituted pyrimidines.
Journal: Arzneimittel-Forschung 20070101
Title: Palmar erythema.
Journal: American journal of clinical dermatology 20070101
Title: Peroxisome proliferators-activated alpha agonist treatment ameliorates hepatic damage in rats with obstructive jaundice: an experimental study.
Journal: BMC gastroenterology 20070101
Title: The Functions of PPARs in Aging and Longevity.
Journal: PPAR research 20070101
Title: Phthalate-Induced Liver Protection against Deleterious Effects of the Th1 Response: A Potentially Serious Health Hazard.
Journal: PPAR research 20070101
Title: Solubilizing properties of new surface-active agents, products of selective oxyethylation of cholic acid. Part I.
Journal: Polimery w medycynie 20070101
Title: Statin-Induced Increase in HDL-C and Renal Function in Coronary Heart Disease Patients.
Journal: The open cardiovascular medicine journal 20070101
Title: Hypertriglyceridemia and Recurrent Pancreatitis following Splenectomy.
Journal: Case reports in gastroenterology 20070101
Title: Waterborne gemfibrozil challenges the hepatic antioxidant defense system and down-regulates peroxisome proliferator-activated receptor beta (PPARbeta) mRNA levels in male goldfish (Carassius auratus).
Journal: Toxicology 20061207
Title: Simultaneous low-density lipoprotein-C lowering and high-density lipoprotein-C elevation for optimum cardiovascular disease prevention with various drug classes, and their combinations: a meta-analysis of 23 randomized lipid trials.
Journal: Current opinion in lipidology 20061201
Title: Reproducible tendinitis-like symptoms related to statin therapy.
Journal: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20061201
Title: Fibrates after the FIELD study: Some answers, more questions.
Journal: Diabetes & vascular disease research 20061201
Title: Nicotinic acid: new/old drug. Immediate or sustained release: too risky for a drug with no proven benefit.
Journal: Prescrire international 20061201
Title: Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance.
Journal: Clinical pharmacology and therapeutics 20061201
Title: Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
Journal: Clinical pharmacology and therapeutics 20061201
Title: Attenuation of wastewater-derived contaminants in an effluent-dominated river.
Journal: Environmental science & technology 20061201
Title: Utilization of a one-dimensional score for surveying chemical-induced changes in expression levels of multiple biomarker gene sets using a large-scale toxicogenomics database.
Journal: The Journal of toxicological sciences 20061201
Title: Profiling of gene expression in rat liver and rat primary cultured hepatocytes treated with peroxisome proliferators.
Journal: The Journal of toxicological sciences 20061201
Title: Management of hyperlipidemia with statins in the older patient.
Journal: Clinical interventions in aging 20061201
Title: Simultaneous quantitation of rosuvastatin and gemfibrozil in human plasma by high-performance liquid chromatography and its application to a pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20061101
Title: Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
Journal: Journal of the National Cancer Institute 20061101
Title: Long term clinical trials: how much information do participants retain from the informed consent process?
Journal: Contemporary clinical trials 20061001
Title: [Gemfibrozil induced rhabdomyolysis in a patient with undiscovered hypothyroidism].
Journal: Anales de medicina interna (Madrid, Spain : 1984) 20061001
Title: Peroxisome proliferator-activated receptors increase human sebum production.
Journal: The Journal of investigative dermatology 20060901
Title: PPAR-alpha and -gamma agonists attenuate diabetic kidney disease in the apolipoprotein E knockout mouse.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060901
Title: Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis.
Journal: Environmental health perspectives 20060901
Title: Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.
Journal: Environmental health perspectives 20060901
Title: Seasonality effects on pharmaceuticals and s-triazine herbicides in wastewater effluent and surface water from the Canadian side of the upper Detroit River.
Journal: Environmental toxicology and chemistry 20060901
Title: Consequences of treated water recycling as regards pharmaceuticals and drugs in surface and ground waters of a medium-sized Mediterranean catchment.
Journal: Environmental science & technology 20060901
Title: A review of omega-3 ethyl esters for cardiovascular prevention and treatment of increased blood triglyceride levels.
Journal: Vascular health and risk management 20060901
Title: The interference of pharmaceuticals with endogenous and xenobiotic metabolizing enzymes in carp liver: an in-vitro study.
Journal: Environmental science & technology 20060815
Title: Agonists of the peroxisome proliferator-activated receptor alpha induce a fiber-type-selective transcriptional response in rat skeletal muscle.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801
Title: Managing diabetic dyslipidaemia--beyond LDL-C:HDL-C and triglycerides.
Journal: Atherosclerosis. Supplements 20060801
Title: The CYP2C8 inhibitor gemfibrozil does not increase the plasma concentrations of zopiclone.
Journal: European journal of clinical pharmacology 20060801
Title: The sense of coherence and incidence of cancer--role of follow-up time and age at baseline.
Journal: Journal of psychosomatic research 20060801
Title: It's all connected.
Journal: The American journal of medicine 20060801
Title: Occurrence of pharmaceutical products in a municipal effluent and toxicity to rainbow trout (Oncorhynchus mykiss) hepatocytes.
Journal: Ecotoxicology and environmental safety 20060701
Title: The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT).
Journal: Atherosclerosis 20060701
Title: Peroxisome proliferator-activated receptor-alpha and retinoid X receptor agonists inhibit inflammatory responses of astrocytes.
Journal: Journal of neuroimmunology 20060701
Title: Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications.
Journal: Vascular pharmacology 20060701
Title: Evaluation of laboratory monitoring alerts within a computerized physician order entry system for medication orders.
Journal: The American journal of managed care 20060701
Title: Pioglitazone is metabolised by CYP2C8 and CYP3A4 in vitro: potential for interactions with CYP2C8 inhibitors.
Journal: Basic & clinical pharmacology & toxicology 20060701
Title: Effects of selected pharmaceutical products on phagocytic activity in Elliptio complanata mussels.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060601
Title: Itraconazole, gemfibrozil and their combination markedly raise the plasma concentrations of loperamide.
Journal: European journal of clinical pharmacology 20060601
Title: Natural attenuation of pharmaceuticals and alkylphenol polyethoxylate metabolites during river transport: photochemical and biological transformation.
Journal: Environmental toxicology and chemistry 20060601
Title: Secondary prevention of ischaemic cardiac events.
Journal: Clinical evidence 20060601
Title: Dyslipidaemia in diabetes.
Journal: Clinical evidence 20060601
Title: Prevention of cardiovascular events in diabetes.
Journal: Clinical evidence 20060601
Title: Metabolic syndrome, inflammation and atherosclerosis.
Journal: Vascular health and risk management 20060601
Title: Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review.
Journal: International journal of nanomedicine 20060601
Title: Determination of acidic drugs and caffeine in municipal wastewaters and receiving waters by gas chromatography-ion trap tandem mass spectrometry.
Journal: Journal of chromatography. A 20060526
Title: Separation of fibrate-type antihyperlipidemic drugs by capillary electrophoresis and their quantitation in pharmaceuticals.
Journal: Journal of pharmaceutical and biomedical analysis 20060503
Title: Factors influencing the intracellular activity of fluoroquinolones: a study using levofloxacin in a Staphylococcus aureus THP-1 monocyte model.
Journal: The Journal of antimicrobial chemotherapy 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Bioactivation of carboxylic acid compounds by UDP-Glucuronosyltransferases to DNA-damaging intermediates: role of glycoxidation and oxidative stress in genotoxicity.
Journal: Chemical research in toxicology 20060501
Title: Statin safety and drug interactions: clinical implications.
Journal: The American journal of cardiology 20060417
Title: Statin safety: a systematic review.
Journal: The American journal of cardiology 20060417
Title: The role of fibrates in a statin world.
Journal: Archives of internal medicine 20060410
Title: Gemfibrozil in the treatment of dyslipidemia: an 18-year mortality follow-up of the Helsinki Heart Study.
Journal: Archives of internal medicine 20060410
Title: The role of transporters in drug interactions.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401
Title: Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation.
Journal: Diabetologia 20060401
Title: Effects of vitamin E and gemfibrozil on lipid profiles, lipid peroxidation and antioxidant status in the elderly and young hyperlipidemic subjects.
Journal: Saudi medical journal 20060401
Title: Meglitinide analogues: a review of clinical data focused on recent trials.
Journal: Diabetes & metabolism 20060401
Title: [Fibrate-induced changes in the serum lipid contents of individual C16 and C18 fatty acids in patients with hyperlipidemia].
Journal: Klinicheskaia laboratornaia diagnostika 20060401
Title: Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial.
Journal: Circulation 20060328
Title: Cardioprotective properties of fibrates: which fibrate, which patients, what mechanism?
Journal: Circulation 20060328
Title: Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents.
Journal: Bioorganic & medicinal chemistry letters 20060101
Title: Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060101
Title: Statin/fibrate combination in patients with metabolic syndrome or diabetes: evaluating the risks of pharmacokinetic drug interactions.
Journal: Expert opinion on drug safety 20060101
Title: Clinical inquiries. What are effective medication combinations for dyslipidemia?
Journal: The Journal of family practice 20060101
Title: Comparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular risk.
Journal: Nutrition & metabolism 20060101
Title: Fibrates in combination with statins in the management of dyslipidemia.
Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060101
Title: Effective use of combination lipid therapy.
Journal: Current atherosclerosis reports 20060101
Title: Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism.
Journal: Drugs of today (Barcelona, Spain : 1998) 20060101
Title: Drug-induced hepatitis in a patient with malignant melanoma treated with interferon alfa 2b adjuvantly who had been administered gemfibrozil in therapy.
Journal: Medical oncology (Northwood, London, England) 20060101
Title: [A case of interstitial lung disease with atorvastatin (Tahor) and a review of the literature about these effects observed under statins].
Journal: Therapie 20060101
Title: [Early use of gemfibrozil in patients with non ST Elevation acute coronary syndrome. Changes of markers of inflammation and von Willebrand factor].
Journal: Kardiologiia 20060101
Title: Atherogenic dyslipidemia in metabolic syndrome and type 2 diabetes: therapeutic options beyond statins.
Journal: Cardiovascular diabetology 20060101
Title: Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma.
Journal: BMC cancer 20060101
Title: Comparison of effects of fibrates in patients with hypertriglyceridemia.
Journal: Advances in therapy 20060101
Title: Tamoxifen-induced severe hypertriglyceridaemia and acute pancreatitis.
Journal: Clinical drug investigation 20060101
Title: Severe combined hyperlipidaemia and retinal lipid infiltration in a patient with Type 2 diabetes mellitus.
Journal: Lipids in health and disease 20060101
Title: Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials.
Journal: Chinese medicine 20060101
Title: Lipid-modifying and pleiotropic effects of gemfibrozil, simvastatin and pravastatin in patients with dyslipidemia.
Journal: Folia medica 20060101
Title: Combination of a sterol absorption inhibitor and cardiovascular agents for the treatment of dyslipidemia.
Journal: Recent patents on cardiovascular drug discovery 20060101
Title: K-111: the emerging evidence for its potential in the treatment of the metabolic syndrome.
Journal: Core evidence 20060101
Title: Effect of gemfibrozil on the pharmacokinetics of pioglitazone.
Journal: European journal of clinical pharmacology 20051201
Title: Potential drug-drug interaction between interferon alfa-2b and gemfibrozil in a patient with malignant melanoma.
Journal: Clinical therapeutics 20051201
Title: Optimal lipid modification: the rationale for combination therapy.
Journal: Vascular health and risk management 20051201
Title: Fibrates inhibit aldose reductase activity in the forward and reverse reactions.
Journal: Biochemical pharmacology 20051125
Title: Statins and PPARalpha agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment.
Journal: Toxicology and applied pharmacology 20051101
Title: 2nd International Symposium on Triglycerides and HDL: lipid abnormalities and their treatment.
Journal: Diabetes care 20051101
Title: Gemfibrozil reduces small low-density lipoprotein more in normolipemic subjects classified as low-density lipoprotein pattern B compared with pattern A.
Journal: The American journal of cardiology 20051101
Title: Effective use of combination lipid therapy.
Journal: Current cardiology reports 20051101
Title: Differential associations of statin and fibrate treatment with carotid arterial remodeling.
Journal: American journal of hypertension 20051101
Title: The forgotten majority: unfinished business in cardiovascular risk reduction.
Journal: Journal of the American College of Cardiology 20051004
Title: Joint Nordic prospective study on human herpesvirus 8 and multiple myeloma risk.
Journal: British journal of cancer 20051003
Title: High-density lipoprotein cholesterol: ready for prime time?
Journal: Singapore medical journal 20051001
Title: Patients with low levels of high-density lipoprotein cholesterol: to treat or not to treat?
Journal: Singapore medical journal 20051001
Title: Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin.
Journal: Basic & clinical pharmacology & toxicology 20051001
Title: Protective effect of coenzyme Q10 in simvastatin and gemfibrozil induced rhabdomyolysis in rats.
Journal: Indian journal of experimental biology 20051001
Title: [Drug combinations: statins and fibrates].
Journal: Arquivos brasileiros de cardiologia 20051001
Title: Enantiomeric separation of gemfibrozil chiral analogues by capillary electrophoresis with heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin as chiral selector.
Journal: Journal of chromatography. A 20050923
Title: What is the most effective strategy for managing diabetic dyslipidaemia?
Journal: Atherosclerosis. Supplements 20050901
Title: Fate of endocrine-disruptor, pharmaceutical, and personal care product chemicals during simulated drinking water treatment processes.
Journal: Environmental science & technology 20050901
Title: A teleost in vitro reporter gene assay to screen for agonists of the peroxisome proliferator-activated receptors.
Journal: Environmental toxicology and chemistry 20050901
Title: Actions of calcium channel blockers on vascular proteoglycan synthesis: relationship to atherosclerosis.
Journal: Vascular health and risk management 20050901
Title: Vascular endothelium as a target of beraprost sodium and fenofibrate for antiatherosclerotic therapy in type 2 diabetes mellitus.
Journal: Vascular health and risk management 20050901
Title: Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia.
Journal: Journal of neuroscience research 20050801
Title: The effects of multiple doses of fenofibrate on the pharmacokinetics of pravastatin and its 3alpha-hydroxy isomeric metabolite.
Journal: Journal of clinical pharmacology 20050801
Title: Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide.
Journal: British journal of clinical pharmacology 20050801
Title: Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites.
Journal: Clinical pharmacology and therapeutics 20050801
Title: PPARs as targets for metabolic and cardiovascular diseases.
Journal: Mini reviews in medicinal chemistry 20050801
Title: Comparison between duration dependent effects of Simvastatin and Gemfibrozil on dyslipidemia in patients with type 2 diabetes.
Journal: JPMA. The Journal of the Pakistan Medical Association 20050801
Title: Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden.
Journal: Journal of hazardous materials 20050715
Title: Low high-density lipoprotein cholesterol disorders and cardiovascular risk: contribution of associated low-density lipoprotein subclass abnormalities.
Journal: Current opinion in cardiology 20050701
Title: Cholesterol levels and statin use in patients with coronary heart disease treated in primary care settings.
Journal: Preventing chronic disease 20050701
Title: Different response of senescent female Sprague-Dawley rats to gemfibrozil and rosiglitazone administration.
Journal: Experimental gerontology 20050701
Title: Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: effects of gemfibrozil.
Journal: Pharmaceutical research 20050701
Title: Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050701
Title: The human lipid regulator, gemfibrozil bioconcentrates and reduces testosterone in the goldfish, Carassius auratus.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20050601
Title: Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage.
Journal: Pharmacogenetics and genomics 20050601
Title: Antiatherogenic properties of fibrates.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050601
Title: A case of hypothyroidism and type 2 diabetes associated with type V hyperlipoproteinemia and eruptive xanthomas.
Journal: Journal of Korean medical science 20050601
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20050601
Title: Photodegradation of common environmental pharmaceuticals and estrogens in river water.
Journal: Environmental toxicology and chemistry 20050601
Title: Synthesis of fenoprofen and gemfibrozil styrene-maleic acid copolymer conjugates.
Journal: Acta pharmaceutica (Zagreb, Croatia) 20050601
Title: Efficacy and safety of rosuvastatin in treatment of dyslipidemia.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050515
Title: The role of lipid management in diabetes.
Journal: Cardiology clinics 20050501
Title: Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone.
Journal: Clinical pharmacology and therapeutics 20050501
Title: [Lipid therapy in risk patients. Do we concentrate too much on LDL cholesterol?].
Journal: MMW Fortschritte der Medizin 20050407
Title: Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20050401
Title: Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater.
Journal: Journal of agricultural and food chemistry 20050309
Title: Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050301
Title: Ongoing clinical trials of the pleiotropic effects of statins.
Journal: Vascular health and risk management 20050301
Title: 1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents.
Journal: Bioorganic & medicinal chemistry letters 20050201
Title: Effects of switching pravastatin to cerivastatin on C-reactive protein, butyrylcholinesterase, and lipids.
Journal: Current medical research and opinion 20050201
Title: Summaries for patients. Targeting cholesterol treatment toward increasing high-density lipoprotein levels.
Journal: Annals of internal medicine 20050118
Title: A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events.
Journal: Annals of internal medicine 20050118
Title: Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia.
Journal: The American journal of cardiology 20050115
Title: De novo synthesis of diacylglycerol in endothelium may mediate the association between PAI-1 and the insulin resistance syndrome.
Journal: Medical hypotheses 20050101
Title: Reporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statin.
Journal: The American journal of cardiology 20050101
Title: The sialic acid content of fibrinogen decreases during pregnancy and increases in response to fibrate therapy.
Journal: Thrombosis research 20050101
Title: Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS.
Journal: Lipids in health and disease 20050101
Title: Cost effectiveness of treating low HDL-cholesterol in the primary prevention of coronary heart disease.
Journal: PharmacoEconomics 20050101
Title: Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes.
Journal: Pharmaceutical research 20050101
Title: Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors.
Journal: Neoplasma 20050101
Title: Study of the liquid chromatography retention of some fibrate-type antihyperlipidemic drugs on C18 and CN columns: application for quantitation in pharmaceutical formulations.
Journal: Journal of AOAC International 20050101
Title: Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions.
Journal: Clinical pharmacokinetics 20050101
Title: Statins research unfinished saga: desirability versus feasibility.
Journal: Cardiovascular diabetology 20050101
Title: Drug interactions of clinical importance with antihyperglycaemic agents: an update.
Journal: Drug safety 20050101
Title: A two-dimensional electrophoresis preliminary approach to human hepatocarcinoma differentiation induced by PPAR-agonists.
Journal: Journal of cellular and molecular medicine 20050101
Title: Comparative bioavailability study with two gemfibrozil tablet formulations in healthy volunteers.
Journal: Arzneimittel-Forschung 20050101
Title: Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481].
Journal: Cardiovascular diabetology 20050101
Title: A new perspective in the treatment of dyslipidemia : can fenofibrate offer unique benefits in the treatment of type 2 diabetes mellitus?
Journal: Treatments in endocrinology 20050101
Title: Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndrome.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101
Title: Association of common variation in the PPARA gene with incident myocardial infarction in individuals with type 2 diabetes: a Go-DARTS study.
Journal: Nuclear receptor 20050101
Title: [Preparation and investigation of gemfibrozil + dimethyl-beta-cyclodextrin products and solid dosage forms].
Journal: Acta pharmaceutica Hungarica 20050101
Title: Determination of fenofibrate and gemfibrozil in pharmaceuticals by densitometric and videodensitometric thin-layer chromatography.
Journal: Journal of AOAC International 20050101
Title: [Withdrawal of cerivastatin revealed a flaw of post-marketing surveillance system in the United States].
Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20050101
Title: Simvastatin: a review.
Journal: Expert opinion on pharmacotherapy 20041201
Title: Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis.
Journal: JAMA 20041201
Title: Potential for conflict of interest in the evaluation of suspected adverse drug reactions: a counterpoint.
Journal: JAMA 20041201
Title: Bayer's response to 'potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis'.
Journal: JAMA 20041201
Title: Pharmacologic treatment of type 2 diabetic dyslipidemia.
Journal: Pharmacotherapy 20041201
Title: Regulation of phase I and phase II steroid metabolism enzymes by PPAR alpha activators.
Journal: Toxicology 20041115
Title: R643G polymorphism in PECAM-1 influences transendothelial migration of monocytes and is associated with progression of CHD and CHD events.
Journal: Atherosclerosis 20041101
Title: Effect of gemfibrozil on change in renal function in men with moderate chronic renal insufficiency and coronary disease.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20041101
Title: Predictors of change in low-density lipoprotein size during lipid-lowering treatment in type 2 diabetes.
Journal: Metabolism: clinical and experimental 20041101
Title: Dysregulation of growth hormone in acquired generalized lipodystrophy.
Journal: Saudi medical journal 20041101
Title: Gene expression analysis of peroxisome proliferators- and phenytoin-induced hepatotoxicity using cDNA microarray.
Journal: The Journal of veterinary medical science 20041101
Title: PPARalpha activators down-regulate CYP2C7, a retinoic acid and testosterone hydroxylase.
Journal: Toxicology 20041015
Title: Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil.
Journal: The Journal of pharmacology and experimental therapeutics 20041001
Title: Polymorphisms in the gene encoding lipoprotein lipase in men with low HDL-C and coronary heart disease: the Veterans Affairs HDL Intervention Trial.
Journal: Journal of lipid research 20041001
Title: Management of hypertriglyceridemia in patients receiving interferon for malignant melanoma.
Journal: The Annals of pharmacotherapy 20041001
Title: Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs.
Journal: Biochemical pharmacology 20041001
Title: Risk of adverse events with fibrates.
Journal: The American journal of cardiology 20041001
Title: Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1.
Journal: PLoS medicine 20041001
Title: Management of dyslipidaemia in HIV-infected patients receiving antiretroviral therapy.
Journal: Antiviral therapy 20041001
Title: Co-induction of methyltransferase Rv0560c by naphthoquinones and fibric acids suggests attenuation of isoprenoid quinone action in Mycobacterium tuberculosis.
Journal: Canadian journal of microbiology 20041001
Title: Gemfibrozil for secondary prevention of cardiovascular events in mild to moderate chronic renal insufficiency.
Journal: Kidney international 20040901
Title: Occurrence and fate of pharmaceuticals and alkylphenol ethoxylate metabolites in an effluent-dominated river and wetland.
Journal: Environmental toxicology and chemistry 20040901
Title: Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil.
Journal: International journal of clinical pharmacology and therapeutics 20040901
Title: PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells.
Journal: Regulatory peptides 20040815
Title: Targeted inactivation of cystic fibrosis transmembrane conductance regulator chloride channel gene prevents ischemic preconditioning in isolated mouse heart.
Journal: Circulation 20040810
Title: Treatment of hyperlipidemia in cardiac transplant recipients.
Journal: American heart journal 20040801
Title: Association between different lipid-lowering treatment strategies and blood pressure control in the Brisighella Heart Study.
Journal: American heart journal 20040801
Title: Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040801
Title: [Alcoholic and non-alcoholic steatohepatitis].
Journal: Therapeutische Umschau. Revue therapeutique 20040801
Title: PPARalpha agonists clofibrate and gemfibrozil inhibit cell growth, down-regulate hCG and up-regulate progesterone secretions in immortalized human trophoblast cells.
Journal: Biochemical pharmacology 20040715
Title: Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications.
Journal: Biochemical and biophysical research communications 20040702
Title: Rhabdomyolysis with HMG-CoA reductase inhibitors and gemfibrozil combination therapy.
Journal: Pharmacoepidemiology and drug safety 20040701
Title: Safety of statins: focus on clinical pharmacokinetics and drug interactions.
Journal: Circulation 20040615
Title: Rhabdomyolysis associated with hydroxymethylglutaryl-coenzyme A reductase inhibitors.
Journal: American heart journal 20040601
Title: How doubling up drugs saves lives. Why doctors increasingly deploy an array of medications all at once.
Journal: Heart advisor 20040601
Title: Prevention of cardiovascular events in diabetes.
Journal: Clinical evidence 20040601
Title: Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells.
Journal: Circulation research 20040514
Title: Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040501
Title: Triglycerides induce leptin resistance at the blood-brain barrier.
Journal: Diabetes 20040501
Title: The effect of gemfibrozil on the pharmacokinetics of rosuvastatin.
Journal: Clinical pharmacology and therapeutics 20040501
Title: [Effects of Shenshuai Yangzhen capsule on lipid metabolism disorder in rats with chronic renal failure].
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20040501
Title: APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study.
Journal: Journal of lipid research 20040401
Title: Effects of PPARgamma and PPARalpha agonists on serum leptin levels in diet-induced obese rats.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040401
Title: The influence of buffer composition on tissue integrity during permeability experiments 'in vitro'.
Journal: International journal of pharmaceutics 20040319
Title: The effect of fibrates and other lipid-lowering drugs on plasma homocysteine levels.
Journal: Expert opinion on drug safety 20040301
Title: Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients.
Journal: European journal of clinical pharmacology 20040201
Title: Early detection of drug interactions utilizing a computerized drug prescription handling system-focus on cerivastatin-gemfibrozil.
Journal: European journal of clinical pharmacology 20040201
Title: Rhabdomyolysis and renal failure associated with gemfibrozil monotherapy.
Journal: The Annals of pharmacotherapy 20040201
Title: Effects of gemfibrozil treatment on vascular reactivity of streptozotocin-diabetic rat aorta.
Journal: The Journal of pharmacy and pharmacology 20040201
Title: Serum homocysteine concentrations, gemfibrozil treatment, and progression of coronary atherosclerosis.
Journal: Atherosclerosis 20040201
Title: Effect of fibrates on postprandial remnant-like particles in patients with combined hyperlipidemia.
Journal: Atherosclerosis 20040201
Title: Influence of lipid lowering fibrates on P-glycoprotein activity in vitro.
Journal: Biochemical pharmacology 20040115
Title: Fibrates for treatment of the metabolic syndrome.
Journal: Current atherosclerosis reports 20040101
Title: Lack of hypotriglyceridemic effect of gemfibrozil as a consequence of age-related changes in rat liver PPARalpha.
Journal: Biochemical pharmacology 20040101
Title: Statin treatment and the natural history of atherosclerotic-related diseases: pathogenic mechanisms and the risk-benefit profile.
Journal: Current pharmaceutical design 20040101
Title: An ounce of prevention. Drugs used to treat hyperlipidemia (Part 1).
Journal: Orthopedic nursing 20040101
Title: Role of fibrates in reducing coronary risk: a UK Consensus.
Journal: Current medical research and opinion 20040101
Title: The effect of alcohol and gemfibrozil co-administration in Wistar rats.
Journal: In vivo (Athens, Greece) 20040101
Title: Rising statin use and effect on ischemic stroke outcome.
Journal: BMC medicine 20040101
Title: Patient with gemfibrozil-controlled hypertriglyceridemia that developed acute pancreatitis after starting ketogenic diet.
Journal: Current surgery 20040101
Title: Repaglinide : a pharmacoeconomic review of its use in type 2 diabetes mellitus.
Journal: PharmacoEconomics 20040101
Title: [Fibrates: mechanism of action, effect on levels of lipids and lipoproteins, risk of coronary events. Part 1. Clofibrate, gemfibrosil, besafibrate].
Journal: Kardiologiia 20040101
Title: Treatment of hyperlipidemia in elderly persons with exercise training, nonpharmacologic therapy, and drug combinations.
Journal: The American journal of geriatric cardiology 20040101
Title: [Cell protection through PPAR nuclear receptor activation].
Journal: Therapie 20040101
Title: Application of UV-derivative spectra for determination of four antihyperlipidaemic drugs in pharmaceutical formulations.
Journal: Acta poloniae pharmaceutica 20040101
Title: Ciprofibrate therapy in patients with hypertriglyceridemia and low high density lipoprotein (HDL)-cholesterol: greater reduction of non-HDL cholesterol in subjects with excess body weight (The CIPROAMLAT study).
Journal: Cardiovascular diabetology 20040101
Title: Effect of gemfibrozil on the metabolism of pitavastatin--determining the best animal model for human CYP and UGT activities.
Journal: Drug metabolism and drug interactions 20040101
Title: Disparities in lipid management for African Americans and Caucasians with coronary artery disease: a national cross-sectional study.
Journal: BMC cardiovascular disorders 20040101
Title: Significance of high density lipoprotein-cholesterol in cardiovascular risk prevention: recommendations of the HDL Forum.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101
Title: Emphysematous cystitis: an unusual disease of the Genito-Urinary system suspected on imaging.
Journal: Annals of clinical microbiology and antimicrobials 20040101
Title: Removal of selected non-steroidal anti-inflammatory drugs (NSAIDs), gemfibrozil, carbamazepine, beta-blockers, trimethoprim and triclosan in conventional wastewater treatment plants in five EU countries and their discharge to the aquatic environment.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20040101
Title: The need for a large-scale trial of fibrate therapy in diabetes: the rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481].
Journal: Cardiovascular diabetology 20040101
Title: Which is the best lipid-modifying strategy in metabolic syndrome and diabetes: fibrates, statins or both?
Journal: Cardiovascular diabetology 20040101
Title: Determination of acidic pharmaceuticals, antibiotics and ivermectin in river sediment using liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. A 20031222
Title: HIV protease inhibitor ritonavir induces lipoatrophy in male mice.
Journal: AIDS research and human retroviruses 20031201
Title: Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants.
Journal: Environmental toxicology and chemistry 20031201
Title: Measurement of diacylglycerol acyltransferase activity in isolated hepatocytes.
Journal: Analytical biochemistry 20031115
Title: Possible differences between fibrates in pharmacokinetic interactions with statins.
Journal: Archives of internal medicine 20031027
Title: Gemfibrozil increases the specific binding of rat-cortex nuclear extracts to a PPRE probe.
Journal: Life sciences 20031024
Title: Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Journal: Journal of medicinal chemistry 20031009
Title: Gemfibrozil considerably increases the plasma concentrations of rosiglitazone.
Journal: Diabetologia 20031001
Title: Effects of baseline level of triglycerides on changes in lipid levels from combined fluvastatin + fibrate (bezafibrate, fenofibrate, or gemfibrozil).
Journal: The American journal of cardiology 20031001
Title: Metabolism and disposition of gemfibrozil in Wistar and multidrug resistance-associated protein 2-deficient TR- rats.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031001
Title: The effects of the phytoestrogenic isoflavone genistein on the hepatic disposition of preformed and hepatically generated gemfibrozil 1-O-acyl glucuronide in the isolated perfused rat liver.
Journal: The Journal of pharmacy and pharmacology 20031001
Title: Effects of metformin or gemfibrozil on the lipodystrophy of HIV-infected patients receiving protease inhibitors.
Journal: Antiviral therapy 20031001
Title: Lipid-lowering drugs and serum liver enzymes: the effects of body weight and baseline enzyme levels.
Journal: Fundamental & clinical pharmacology 20030801
Title: Antibodies to human heat shock protein 60, hypertension and dyslipidemia. A study of joint effects on coronary risk.
Journal: Atherosclerosis 20030801
Title: Subcutaneous cholesterol nodules: a case report.
Journal: Joint, bone, spine : revue du rhumatisme 20030801
Title: Effects of peroxisome proliferators gemfibrozil and clofibrate on syntheses of dolichol and cholesterol in rat liver.
Journal: Journal of biochemistry 20030801
Title: Sensitive method for the quantitative determination of gemfibrozil in dog plasma by liquid-liquid cartridge extraction and liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705
Title: Efficacy of atorvastatin and gemfibrozil, alone and in low dose combination, in the treatment of diabetic dyslipidemia.
Journal: The Journal of clinical endocrinology and metabolism 20030701
Title: Therapeutic implications of recent ATP III guidelines and the important role of combination therapy in total dyslipidemia management.
Journal: Current opinion in cardiology 20030701
Title: Emerging importance of HDL cholesterol in developing high-risk coronary plaques in acute coronary syndromes.
Journal: Current opinion in cardiology 20030701
Title: Cardioprotective activity of synthetic guggulsterone (E and Z-isomers) in isoproterenol induced myocardial ischemia in rats: A comparative study.
Journal: Indian journal of clinical biochemistry : IJCB 20030701
Title: Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors.
Journal: Endocrinology 20030601
Title: Managing lipid disorders: further evaluation of the VA-HIT.
Journal: Current diabetes reports 20030601
Title: Combination lipid-lowering therapy in diabetes.
Journal: Current diabetes reports 20030601
Title: An observational study of severe hypertriglyceridemia, hypertriglyceridemic acute pancreatitis, and failure of triglyceride-lowering therapy when estrogens are given to women with and without familial hypertriglyceridemia.
Journal: Clinica chimica acta; international journal of clinical chemistry 20030601
Title: Commentary. Secondary causes of hypertriglyceridemia and pancreatitis.
Journal: Clinica chimica acta; international journal of clinical chemistry 20030601
Title: Gemfibrozil reduces release of tumor necrosis factor-alpha in peripheral blood mononuclear cells from healthy subjects and patients with coronary heart disease.
Journal: Clinica chimica acta; international journal of clinical chemistry 20030601
Title: Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance.
Journal: Clinical pharmacology and therapeutics 20030601
Title: Fibrates and their newly synthesized glycinate or glycinate-methylester derivatives: comparison of the interactions with liver cytochrome P450 dependent monooxygenase- and oxidase-functions in vitro.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601
Title: Reverse cholesterol transport, high density lipoproteins and HDL cholesterol: recent data.
Journal: Diabetes & metabolism 20030601
Title: Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus.
Journal: The Journal of antimicrobial chemotherapy 20030501
Title: Insulin resistance and cardiovascular events with low HDL cholesterol: the Veterans Affairs HDL Intervention Trial (VA-HIT).
Journal: Diabetes care 20030501
Title: A novel functional polymorphism in the PECAM-1 gene (53G>A) is associated with progression of atherosclerosis in the LOCAT and REGRESS studies.
Journal: Atherosclerosis 20030501
Title: Current best treatment for non-alcoholic fatty liver disease.
Journal: Expert opinion on pharmacotherapy 20030501
Title: Preparation of antiserum against rat delta6-desaturase and its use to evaluate the desaturase protein levels in rats treated with gemfibrozil, a ligand for peroxisome proliferator-activated receptor alpha.
Journal: Bioscience, biotechnology, and biochemistry 20030501
Title: Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro: the effect of mucolysis and ATP-depletion.
Journal: International journal of pharmaceutics 20030430
Title: Statins and fibrates for the treatment of hyperlipidaemia in HIV-infected patients receiving HAART.
Journal: AIDS (London, England) 20030411
Title: Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030401
Title: Gemfibrozil reduces plasma C-reactive protein levels in abdominally obese men with the atherogenic dyslipidemia of the metabolic syndrome.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030401
Title: Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basic esters of ampicillin, in comparison with chloroquine and azithromycin.
Journal: Pharmaceutical research 20030401
Title: Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.
Journal: Archives of internal medicine 20030324
Title: [Antilipemic therapy and rhabdomyolysis].
Journal: Orvosi hetilap 20030316
Title: Opposing mechanisms of NADPH-cytochrome P450 oxidoreductase regulation by peroxisome proliferators.
Journal: Biochemical pharmacology 20030315
Title: Spectrofluorimetric and micelle-enhanced spectrofluorimetric methods for the determination of gemfibrozil in pharmaceutical preparations.
Journal: Journal of pharmaceutical and biomedical analysis 20030310
Title: Effects of hypolipidemic treatment on serum markers of vascular inflammation in dyslipidemic men.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20030301
Title: Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030301
Title: Self-micellization of gemfibrozil 1-O-beta acyl glucuronide in aqueous solution.
Journal: Pharmaceutical research 20030301
Title: Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide.
Journal: Diabetologia 20030301
Title: HDL in atherosclerosis: actor or bystander?
Journal: Atherosclerosis. Supplements 20030301
Title: Frequency of creatine kinase elevation during treatment with fluvastatin in combination with fibrates (bezafibrate, fenofibrate, or gemfibrozil).
Journal: The American journal of cardiology 20030115
Title: Myoglobinuria and COX deficiency in a patient taking cerivastatin and gemfibrozil.
Journal: Neurology 20030114
Title: Fenofibrate-induced hyperhomocysteinaemia: clinical implications and management.
Journal: Drug safety 20030101
Title: Acute rhabdomyolysis after gemfibrozil therapy in a pregnant patient complicated with acute pancreatitis and hypertriglycerdemia while receiving continuous veno-venous hemofiltration therapy.
Journal: Renal failure 20030101
Title: Prevalence of antilipemic drug use in Taiwan: analysis of a sampling cohort within the national health insurance.
Journal: Journal of the Chinese Medical Association : JCMA 20030101
Title: Melanoma chemoprevention: a role for statins or fibrates?
Journal: American journal of therapeutics 20030101
Title: Use of a quadrupole linear ion trap mass spectrometer in metabolite identification and bioanalysis.
Journal: Rapid communications in mass spectrometry : RCM 20030101
Title: Cardiovascular complications of diabetes: prevention and management.
Journal: Clinical cornerstone 20030101
Title: Statin-fibrate combination: therapy for hyperlipidemia: a review.
Journal: Current medical research and opinion 20030101
Title: [Antilipemics: results of large studies].
Journal: Therapie 20030101
Title: [Drug interactions with antilipemics].
Journal: Therapie 20030101
Title: Metabolic syndrome and type 2 diabetes mellitus: focus on peroxisome proliferator activated receptors (PPAR).
Journal: Cardiovascular diabetology 20030101
Title: Recombinant apolipoprotein A-I(Milano): a novel agent for the induction of regression of atherosclerotic plaques.
Journal: Annals of medicine 20030101
Title: The sense of coherence, occupation and all-cause mortality in the Helsinki Heart Study.
Journal: European journal of epidemiology 20030101
Title: [Renal dyslipidemia in patients on chronic hemodialysis].
Journal: Lijecnicki vjesnik 20030101
Title: Beneficial effects of fish liver preparations of sea bass (Lates calcarifer) versus gemfibrozil in high fat diet-induced lipid-intolerant rats.
Journal: Journal of medicinal food 20030101
Title: Clinical pharmacokinetics of atorvastatin.
Journal: Clinical pharmacokinetics 20030101
Title: Pharmacological comparison of the statins.
Journal: Arzneimittel-Forschung 20030101
Title: [Drug safety. Notes regarding drug surveillance].
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101
Title: Effectiveness of statin-gemfibrozil combination therapy in patients with mixed hyperlipidemia: experience of a community lipid clinic and safety review from the literature.
Journal: Preventive cardiology 20030101
Title: Overview of pharmacologic therapy for the treatment of dyslipidemia.
Journal: Journal of managed care pharmacy : JMCP 20030101
Title: Studies on the interaction between fibrates and statins using human hepatic microsomes.
Journal: Arzneimittel-Forschung 20030101
Title: Interaction between fibrates and statins--metabolic interactions with gemfibrozil.
Journal: Drug metabolism and drug interactions 20030101
Title: Combination therapy with an HMG-CoA reductase inhibitor and a fibric acid derivative: a critical review of potential benefits and drawbacks.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101
Title: Optimal therapy of low levels of high density lipoprotein-cholesterol.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101
Title: Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials.
Journal: BMC family practice 20030101
Title: Pharmacoeconomic aspects of patients treated by hemodialysis.
Journal: Bratislavske lekarske listy 20030101
Title: Effects of gemfibrozil conversion to fenofibrate on lipids in patients on statin therapy.
Journal: The American journal of cardiology 20021215
Title: Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201
Title: HDL and triglyceride as therapeutic targets.
Journal: Current opinion in lipidology 20021201
Title: Lipid-lowering therapy in people with type 2 diabetes.
Journal: Current opinion in lipidology 20021201
Title: Role of lipid-modifying therapy in the prevention of initial and recurrent stroke.
Journal: Current opinion in lipidology 20021201
Title: Gemfibrozil encapsulation and release from microspheres and macromolecular conjugates.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20021201
Title: Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT).
Journal: Archives of internal medicine 20021201
Title: Comparison of gemfibrozil and fenofibrate in patients with dyslipidemic coronary heart disease.
Journal: Pharmacotherapy 20021201
Title: Gemfibrozil greatly increases plasma concentrations of cerivastatin.
Journal: Clinical pharmacology and therapeutics 20021201
Title: Fibrate treatment does not modify the expression of acyl coenzyme A oxidase in human liver.
Journal: Clinical pharmacology and therapeutics 20021201
Title: High rates of adverse effects and patient unawareness of withdrawn lipid-lowering drug combination in a public hospital clinic.
Journal: Pharmacoepidemiology and drug safety 20021201
Title: Fenofibrate in the treatment of dyslipidemia: a review of the data as they relate to the new suprabioavailable tablet formulation.
Journal: Clinical therapeutics 20021201
Title: Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes.
Journal: The Journal of biological chemistry 20021129
Title: A randomized, double-blind study of gemfibrozil for the treatment of protease inhibitor-associated hypertriglyceridaemia.
Journal: AIDS (London, England) 20021108
Title: Effects of various fibrates on serum alkaline phosphatase activity.
Journal: Atherosclerosis 20021101
Title: Effects of fibrates on metabolism of statins in human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20021101
Title: Rhabdomyolysis associated with gemfibrozil-colchicine therapy.
Journal: The Annals of pharmacotherapy 20021101
Title: Optimizing bexarotene therapy for cutaneous T-cell lymphoma.
Journal: Journal of the American Academy of Dermatology 20021101
Title: Effect of gemfibrozil on apolipoprotein B secretion and diacylglycerol acyltransferase activity in human hepatoblastoma (HepG2) cells.
Journal: Atherosclerosis 20021001
Title: Comparison in patients with type 2 diabetes of fibric acid versus hepatic hydroxymethyl glutaryl-coenzyme a reductase inhibitor treatment of combined dyslipidemia.
Journal: Metabolism: clinical and experimental 20021001
Title: Treatment of non-alcoholic steatohepatitis.
Journal: Best practice & research. Clinical gastroenterology 20021001
Title: Thiourea-based gemfibrozil analogues as HDL-elevating agents.
Journal: Bioorganic & medicinal chemistry letters 20020902
Title: Cerivastatin and gemfibrozil-induced cardiac rhabdomyolysis.
Journal: The American journal of forensic medicine and pathology 20020901
Title: Peroxisome proliferators do not activate the transcription factors AP-1, early growth response-1, or heat shock factors 1 and 2 in rats or hamsters.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020901
Title: A safety look at currently available statins.
Journal: Expert opinion on drug safety 20020901
Title: Rat liver acyl-CoA synthetase 4 is a peripheral-membrane protein located in two distinct subcellular organelles, peroxisomes, and mitochondrial-associated membrane.
Journal: Archives of biochemistry and biophysics 20020815
Title: Gemfibrozil lowers plasma lipids and increases polyunsaturated fatty acid content and oxidative susceptibility of lipoproteins in hypertriglyceridemia.
Journal: Clinica chimica acta; international journal of clinical chemistry 20020801
Title: Severe rhabdomyolysis related to cerivastatin without gemfibrozil.
Journal: Annals of internal medicine 20020702
Title: Effect of albumin and cytosol on enzyme kinetics of tolbutamide hydroxylation and on inhibition of CYP2C9 by gemfibrozil in human liver microsomes.
Journal: The Journal of pharmacology and experimental therapeutics 20020701
Title: Rhabdomyolysis-related renal tubular damage studied by proton nuclear magnetic resonance spectroscopy of urine.
Journal: Clinical chemistry 20020701
Title: Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20020701
Title: Influence of the angiotensin-converting enzyme gene insertion/deletion polymorphism on lipoprotein/lipid response to gemfibrozil.
Journal: Clinical genetics 20020701
Title: Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis.
Journal: Pharmacology & therapeutics 20020701
Title: Ligand and coactivator recruitment preferences of peroxisome proliferator activated receptor alpha.
Journal: The Journal of steroid biochemistry and molecular biology 20020701
Title: Detection of pharmaceutical contaminations of river, pond, and tap water from Cologne (Germany) and surroundings.
Journal: International journal of hygiene and environmental health 20020701
Title: Treatment of dyslipidaemia in high-risk patients: too little, too late.
Journal: International journal of clinical practice. Supplement 20020701
Title: Coenzyme Q10 and cardiovascular disease: a review.
Journal: The Journal of cardiovascular nursing 20020701
Title: Gene expression analysis reveals chemical-specific profiles.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020601
Title: Prediction of compound signature using high density gene expression profiling.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020601
Title: Mechanistic studies on metabolic interactions between gemfibrozil and statins.
Journal: The Journal of pharmacology and experimental therapeutics 20020601
Title: Asymptomatic acute pancreatitis due to tamoxifen-induced severe hypertriglyceridemia in a patient with diabetes mellitus and breast cancer.
Journal: Journal of chemotherapy (Florence, Italy) 20020601
Title: [Metabolic modifications related to immunosuppressive drugs].
Journal: Revue medicale de Bruxelles 20020601
Title: Computational selection of distinct class- and subclass-specific gene expression signatures.
Journal: Journal of biomedical informatics 20020601
Title: Myopathy Associated With HMG-CoA Reductase Inhibitors (Statins): A Series of 10 Patients and Review of the Literature.
Journal: Journal of clinical neuromuscular disease 20020601
Title: Effects of a lipid lowering fibrate and hormone replacement therapy on serum lipids and lipoproteins in overweight postmenopausal women with elevated triglycerides.
Journal: Maturitas 20020520
Title: Differential effects of gemfibrozil on migration, proliferation and proteoglycan production in human vascular smooth muscle cells.
Journal: Atherosclerosis 20020501
Title: A comparison of pravastatin and gemfibrozil in the treatment of dyslipoproteinemia in patients with non-insulin-dependent diabetes mellitus.
Journal: Atherosclerosis 20020501
Title: Rhabdomyolysis after concomitant use of cyclosporine, simvastatin, gemfibrozil, and itraconazole.
Journal: The Annals of pharmacotherapy 20020501
Title: Stroke prevention: management of modifiable vascular risk factors.
Journal: Journal of neurology 20020501
Title: Possible mechanisms of the fibrate-induced increase in serum creatinine.
Journal: Clinical nephrology 20020501
Title: Postprandial lipemia--effect of lipid-lowering drugs.
Journal: Atherosclerosis. Supplements 20020501
Title: Effects of gemfibrozil on insulin resistance to fat metabolism in subjects with type 2 diabetes and hypertriglyceridaemia.
Journal: Diabetes, obesity & metabolism 20020501
Title: Analysis of acidic drugs in the effluents of sewage treatment plants using liquid chromatography-electrospray ionization tandem mass spectrometry.
Journal: Journal of chromatography. A 20020405
Title: Fibrate-induced increase in serum urea and creatinine levels.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020401
Title: Severe rhabdomyolysis and cerivastatin-gemfibrozil combination therapy.
Journal: The Annals of pharmacotherapy 20020401
Title: A new reality: achieving cholesterol-lowering goals in clinical practice.
Journal: Atherosclerosis. Supplements 20020401
Title: Gateways to Clinical Trials.
Journal: Methods and findings in experimental and clinical pharmacology 20020401
Title: Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease.
Journal: Circulation 20020326
Title: Synthesis and antiplatelet activity of gemfibrozil chiral analogues.
Journal: Bioorganic & medicinal chemistry letters 20020311
Title: Myopathy and rhabdomyolysis with lipid-lowering drugs.
Journal: Toxicology letters 20020310
Title: Are high-density lipoprotein and triglyceride levels important in secondary prevention: impressions from the BIP and VA-HIT trials.
Journal: International journal of cardiology 20020301
Title: Analysis of serious adverse events. Lipid-lowering therapy revisited.
Journal: Canadian family physician Medecin de famille canadien 20020301
Title: Successful pregnancy outcome in a patient with severe chylomicronemia due to compound heterozygosity for mutant lipoprotein lipase.
Journal: Clinical biochemistry 20020301
Title: Statin stories.
Journal: Diabetes, obesity & metabolism 20020301
Title: Rhabdomyolysis associated with cerivastatin plus gemfibrozil combined regimen.
Journal: The British journal of general practice : the journal of the Royal College of General Practitioners 20020301
Title: Therapy and clinical trials.
Journal: Current opinion in lipidology 20020201
Title: The study on a PVC membrane electrode for gemfibrozil.
Journal: Biological & pharmaceutical bulletin 20020201
Title: Severe hypertriglyceridemia and pancreatitis following hormone replacement prior to cryothaw transfer.
Journal: Journal of assisted reproduction and genetics 20020201
Title: Atorvastatin versus four statin-fibrate combinations in patients with familial combined hyperlipidaemia.
Journal: Journal of cardiovascular risk 20020201
Title: Cost-effectiveness of gemfibrozil for coronary heart disease patients with low levels of high-density lipoprotein cholesterol: the Department of Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial.
Journal: Archives of internal medicine 20020128
Title: Sexual dysfunction secondary to gemfibrozil.
Journal: Pharmacotherapy 20020101
Title: LDL-cholesterol lowering effect of a generic product of simvastatin compared to simvastatin (Zocor) in Thai hypercholesterolemic subjects -- a randomized crossover study, the first report from Thailand.
Journal: BMC clinical pharmacology 20020101
Title: Effect of peroxisome proliferators on the methylation and protein level of the c-myc protooncogene in B6C3F1 mice liver.
Journal: Journal of biochemical and molecular toxicology 20020101
Title: The effects of gemfibrozil on hyperlipidemia in children with persistent nephrotic syndrome.
Journal: The Turkish journal of pediatrics 20020101
Title: Use of fibrates in the management of hyperlipidemia in HIV-infected patients receiving HAART.
Journal: Infection 20020101
Title: Fenofibrate of gemfibrozil for treatment of types IIa and IIb primary hyperlipoproteinemia: a randomized, double-blind, crossover study.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101
Title: Beyond LDL-C--the importance of raising HDL-C.
Journal: Current medical research and opinion 20020101
Title: Recurrent hypoglycaemic episodes in a patient with Type 2 diabetes under fibrate therapy.
Journal: Journal of diabetes and its complications 20020101
Title: Lipids in end-stage renal disease.
Journal: Journal of nephrology 20020101
Title: Effect of ciprofibrate on C-reactive protein and fibrinogen levels.
Journal: Angiology 20020101
Title: Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors.
Journal: Clinical pharmacokinetics 20020101
Title: Lipid-lowering drugs: are adverse effects predictable and reversible?
Journal: Cardiology 20020101
Title: Pharmacologic therapy of lipid disorders in the elderly.
Journal: The American journal of geriatric cardiology 20020101
Title: Results of use of metformin and replacement of starch with saturated fat in diets of patients with type 2 diabetes.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101
Title: Combination of gemfibrozil and orlistat for treatment of combined hyperlipidemia with predominant hypertriglyceridemia.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101
Title: [Rhabdomyolysis, acute renal failure and use of cerivastatin combined with gemfibrozil. New evidence].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20020101
Title: Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil.
Journal: Genetics in medicine : official journal of the American College of Medical Genetics 20020101
Title: Micronised fenofibrate: an updated review of its clinical efficacy in the management of dyslipidaemia.
Journal: Drugs 20020101
Title: Fate of pharmaceuticals during indirect potable reuse.
Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20020101
Title: Low serum levels of high-density lipoprotein cholesterol and hypolipidaemic treatment.
Journal: Current medical research and opinion 20020101
Title: Effects of fibrates on serum metabolic parameters.
Journal: Current medical research and opinion 20020101
Title: HMG CoA reductase-inhibitor-related myopathy and the influence of drug interactions.
Journal: Internal medicine journal 20020101
Title: Rhabdomyolysis from the combination of a statin and gemfibrozil: an uncommon but serious adverse reaction.
Journal: WMJ : official publication of the State Medical Society of Wisconsin 20020101
Title: A multidisciplinary program for achieving lipid goals in chronic hemodialysis patients.
Journal: BMC nephrology 20020101
Title: Ezetimibe: the first in a novel class of selective cholesterol-absorption inhibitors.
Journal: Heart disease (Hagerstown, Md.) 20020101
Title: The anatomy of a clinical trial. The West of Scotland Coronary Prevention Study.
Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20020101
Title: Strategies for minimizing hyperlipidemia after cardiac transplantation.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
Title: Management of protease inhibitor-associated hyperlipidemia.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
Title: Micronized fenofibrate in dyslipidemia: a focus on plasma high-density lipoprotein cholesterol (HDL-C) levels.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
Title: Treatment of nonalcoholic fatty liver disease.
Journal: Annals of hepatology 20020101
Title: [Myopathy with rhabdomyolysis as an adverse effect of simultaneous treatment with cerivastatin and gemfibrozil].
Journal: Lijecnicki vjesnik 20020101
Title: Targeting low high-density lipoprotein cholesterol for therapy: lessons from the Veterans Affairs High-density Lipoprotein Intervention Trial.
Journal: The American journal of cardiology 20011220
Title: Determination of drugs in surface water and wastewater samples by liquid chromatography-mass spectrometry: methods and preliminary results including toxicity studies with Vibrio fischeri.
Journal: Journal of chromatography. A 20011214
Title: Rhabdomyolysis with HMG CoA reductase inhibitors: a class effect?
Journal: Journal of clinical pharmacy and therapeutics 20011201
Title: Treatment for the procoagulant state in type 2 diabetes.
Journal: Endocrinology and metabolism clinics of North America 20011201
Title: Massive rhabdomyolysis and life threatening hyperkalaemia in a patient with the combination of cerivastatin and gemfibrozil.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011201
Title: [Lipid-lowering drugs].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011201
Title: [Rhabdomyolysis associated with combined treatment of cerivastatin and gemfibrozil].
Journal: Revista clinica espanola 20011201
Title: Eruptive xanthomas.
Journal: Dermatology online journal 20011201
Title: Effects of fenofibrate and gemfibrozil on plasma homocysteine.
Journal: Lancet (London, England) 20011124
Title: Effects of fenofibrate and gemfibrozil on plasma homocysteine.
Journal: Lancet (London, England) 20011124
Title: Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Journal: Chemical communications (Cambridge, England) 20011121
Title: Statin-associated myopathy.
Journal: The Medical journal of Australia 20011105
Title: Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20011101
Title: Are high density lipoprotein (HDL) and triglyceride levels relevant in stroke prevention?
Journal: Cardiovascular research 20011101
Title: Gemfibrozil increases paraoxonase activity in type 2 diabetic patients. A new hypothesis of the beneficial action of fibrates?
Journal: Diabetes & metabolism 20011101
Title: Niacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterol.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20011101
Title: Clinical inquiries. What laboratory monitoring is appropriate to detect adverse drug reactions in patients on cholesterol-lowering agents?
Journal: The Journal of family practice 20011101
Title: PPARS, metabolic disease and atherosclerosis.
Journal: Pharmacological research 20011101
Title: Ciprofibrate versus gemfibrozil in the treatment of mixed hyperlipidemias: an open-label, multicenter study.
Journal: Metabolism: clinical and experimental 20011101
Title: Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of glimepiride.
Journal: Clinical pharmacology and therapeutics 20011101
Title: Effect of trans-dehydrocrotonin, a 19-nor-clerodane diterpene from Croton cajucara on experimental hypertriglyceridaemia and hypercholesterolaemia induced by Triton WR 1339 (tyloxapol) in mice.
Journal: Planta medica 20011101
Title: Attenuation by fibrates of plasminogen activator inhibitor type-1 expression in human arterial smooth muscle cells.
Journal: Thrombosis and haemostasis 20011101
Title: [Cerivastatin and gemfibrozil: a dangerous combination].
Journal: Atencion primaria 20011015
Title: Cyclic nucleotides in platelets of genetically hypertriglyceridemic and hypertensive rats. Thrombin and nitric oxide responses are unrelated to plasma triglyceride levels.
Journal: Thrombosis research 20011001
Title: Serum magnesium status during lipid-lowering drug treatment in non-insulin-dependent diabetic patients.
Journal: Metabolism: clinical and experimental 20011001
Title: Fatal rhabdomyolysis caused by lipid-lowering therapy.
Journal: Southern medical journal 20011001
Title: Increase in hepatic expression of SREBP-2 by gemfibrozil administration to rats.
Journal: Biochemical pharmacology 20010915
Title: [Severe rhabdomyolysis associated with cerivastatin and gemfibrozil].
Journal: Medicina clinica 20010915
Title: Bayer pulls cerivastatin (Baycol) from market.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010904
Title: New developments in the prevention of atherosclerosis in patients with low high-density lipoprotein cholesterol.
Journal: Current atherosclerosis reports 20010901
Title: Is the relationship between adipose tissue and waist girth altered by weight loss in obese men?
Journal: Obesity research 20010901
Title: Smoking diminishes the beneficial effect of statins: observations from the landmark trials.
Journal: Angiology 20010901
Title: Cerivastatin and gemfibrozil-associated rhabdomyolysis.
Journal: The Annals of pharmacotherapy 20010901
Title: [Cholestatic hepatitis caused by gemfibrozil].
Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20010901
Title: Molecular basis for the effect of lipid lowering drugs on growth factors after de-endothelialization.
Journal: Chinese medical journal 20010901
Title: Statin safety.
Journal: Nursing standard (Royal College of Nursing (Great Britain) : 1987) 20010901
Title: Altered expression of the carboxylesterases ES-4 and ES-10 by peroxisome proliferator chemicals.
Journal: Toxicology 20010828
Title: Baycol withdrawn from market.
Journal: Circulation 20010821
Title: Bayer decides to withdraw cholesterol lowering drug.
Journal: BMJ (Clinical research ed.) 20010818
Title: A sensitive method for the determination of gemfibrozil in human plasma samples by RP-LC.
Journal: Journal of pharmaceutical and biomedical analysis 20010801
Title: PPARalpha-dependent induction of liver microsomal esterification of estradiol and testosterone by a prototypical peroxisome proliferator.
Journal: Endocrinology 20010801
Title: Gemfibrozil treatment potentiates oxidative resistance of high-density lipoprotein in hypertriglyceridemic patients.
Journal: European journal of clinical investigation 20010801
Title: Effect of a six month gemfibrozil treatment and dietary recommendations on the metabolic risk profile of visceral obese men.
Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010801
Title: Inhibitory action of gemfibrozil on cholesterol absorption in rat intestine.
Journal: Journal of lipid research 20010801
Title: [Fatal rhabdomyolysis caused by cerivastatin].
Journal: Revue medicale de Liege 20010801
Title: Rhabdomyolysis and acute renal failure following a switchover of therapy between two fibric acid derivatives.
Journal: Singapore medical journal 20010801
Title: The effects of lipid-lowering agents on acute renal allograft rejection.
Journal: Transplantation 20010727
Title: Effects of fenofibrate and gemfibrozil on plasma homocysteine.
Journal: Lancet (London, England) 20010707
Title: Differential activation of hepatic NF-kappaB in rats and hamsters by the peroxisome proliferators Wy-14,643, gemfibrozil, and dibutyl phthalate.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010701
Title: Remnant-like lipoprotein particle cholesterol concentration and progression of coronary and vein-graft atherosclerosis in response to gemfibrozil treatment.
Journal: Atherosclerosis 20010701
Title: Postprandial remnant-like lipoproteins in hypertriglyceridemia.
Journal: The Journal of clinical endocrinology and metabolism 20010701
Title: Fenofibrate and warfarin interaction.
Journal: Pharmacotherapy 20010701
Title: Gemfibrozil improves insulin sensitivity and flow-mediated vasodilatation in type 2 diabetic patients.
Journal: European journal of clinical investigation 20010701
Title: [Peroxisome proliferator-activated receptors (PPARs) in the vessel wall: new regulators of gene expression in vascular cells].
Journal: Zeitschrift fur Kardiologie 20010701
Title: Gemfibrozil prevents major coronary events by increasing HDL-cholesterol and more.
Journal: Expert opinion on pharmacotherapy 20010701
Title: Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT).
Journal: Circulation 20010612
Title: Normocholesterolaemic dyslipidaemia: is there a role for fibrates?
Journal: The Medical journal of Australia 20010604
Title: Normocholesterolaemic dysslipidaemia: is there a role for fibrates?
Journal: The Medical journal of Australia 20010604
Title: Effect of statin versus fibrate on postprandial endothelial dysfunction: role of remnant-like particles.
Journal: Cardiovascular research 20010601
Title: Effect of gemfibrozil on the composition and oxidation properties of very-low-density lipoprotein and high-density lipoprotein in patients with hypertriglyceridemia.
Journal: The Journal of laboratory and clinical medicine 20010601
Title: Combination therapy with cerivastatin and gemfibrozil causing rhabdomyolysis: is the interaction predictable?
Journal: The American journal of medicine 20010601
Title: Fibrate treatment can increase serum creatinine levels.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010601
Title: Ciprofibrate versus gemfibrozil in the treatment of mixed hyperlipidemias: an open-label, multicenter study.
Journal: Metabolism: clinical and experimental 20010601
Title: Choice of lipid-regulating drugs.
Journal: The Medical letter on drugs and therapeutics 20010528
Title: New recommendations from the 1999 American College of Cardiology/American Heart Association acute myocardial infarction guidelines.
Journal: The Annals of pharmacotherapy 20010501
Title: Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate.
Journal: Clinical pharmacology and therapeutics 20010501
Title: PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice.
Journal: The Journal of clinical investigation 20010415
Title: Rhabdomyolysis after cerivastatin-gemfibrozil therapy in an HIV-infected patient with protease inhibitor-related hyperlipidemia.
Journal: AIDS (London, England) 20010413
Title: Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010401
Title: Antiviral activity of lovastatin against respiratory syncytial virus in vivo and in vitro.
Journal: Antimicrobial agents and chemotherapy 20010401
Title: [Rhabdomyolysis complicated with acute renal insufficiency in a patient treated with gemfibrozil and cerivastatin].
Journal: Revista clinica espanola 20010401
Title: Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial.
Journal: JAMA 20010328
Title: Statin-fibrate combinations in patients with combined hyperlipedemia.
Journal: Atherosclerosis 20010301
Title: [Helsinki Heart Study].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: [VA-HIT Study [Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study]].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: [Gemfibrozil: new aspects in clinical use].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301
Title: HMG-CoA Reductase Inhibitor Myopathy: Clinical, Electrophysiological, and Pathologic Data in Five Patients.
Journal: Journal of clinical neuromuscular disease 20010301
Title: Effects of peroxisome proliferators on glutathione and glutathione-related enzymes in rats and hamsters.
Journal: Toxicology and applied pharmacology 20010215
Title: Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010201
Title: The effects of gemfibrozil upon the metabolism of chylomicron-like emulsions in patients with endogenous hypertriglyceridemia.
Journal: Cardiovascular research 20010201
Title: Statins for stroke: the second story?
Journal: Circulation 20010123
Title: [The role of HDL in the prevention of cardiovascular events].
Journal: Orvosi hetilap 20010121
Title: Normocholesterolaemic dyslipidaemia: is there a role for fibrates?
Journal: The Medical journal of Australia 20010115
Title: Stimulatory effect of clofibrate and gemfibrozil administration on the formation of fatty acid esters of estradiol by rat liver microsomes.
Journal: The Journal of pharmacology and experimental therapeutics 20010101
Title: Statins in children: what do we know and what do we need to do?
Journal: Current atherosclerosis reports 20010101
Title: The role of fibric acids in atherosclerosis.
Journal: Current atherosclerosis reports 20010101
Title: Deterioration in renal function associated with fibrate therapy.
Journal: Clinical nephrology 20010101
Title: Short-term gemfibrozil treatment reverses lipid profile and peroxidation but does not alter blood glucose and tissue antioxidant enzymes in chronically diabetic rats.
Journal: Molecular and cellular biochemistry 20010101
Title: Treatment of nonalcoholic fatty liver: present and emerging therapies.
Journal: Seminars in liver disease 20010101
Title: Treatment of dyslipoproteinemia in the metabolic syndrome.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101
Title: Severe rhabdomyolysis associated with the cerivastin-gemfibrozil combination therapy: report of a case.
Journal: Texas Heart Institute journal 20010101
Title: Hypertriglyceridemia: a review of clinical relevance and treatment options: focus on cerivastatin.
Journal: Current medical research and opinion 20010101
Title: Statin-fibrate combination therapy.
Journal: The Annals of pharmacotherapy 20010101
Title: Hypercholesterolemia, lipid-lowering agents, and the risk for brain infarction.
Journal: Neurology 20010101
Title: [Fibrates in the secondary prevention of ischemic cardiopathy].
Journal: Archivos de cardiologia de Mexico 20010101
Title: [Rhabdomyolysis and anuric kidney failure induced by the treatment with a gemfibrozil-cerivastatin combination].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101
Title: A risk factor for atherosclerosis: triglyceride-rich lipoproteins.
Journal: Advances in internal medicine 20010101
Title: Drug treatment of combined hyperlipidemia.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20010101
Title: Fibrate-induced increase in blood urea and creatinine: is gemfibrozil the only innocuous agent?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20001201
Title: A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report.
Journal: Angiology 20000801
Title: Evidence against the peroxisome proliferator-activated receptor alpha (PPARalpha) as the mediator for polyunsaturated fatty acid suppression of hepatic L-pyruvate kinase gene transcription.
Journal: Journal of lipid research 20000501
Title: Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations.
Journal: Cardiology 20000101
Title: Fibrates, dyslipoproteinaemia and cardiovascular disease.
Journal: Current opinion in lipidology 19991201
Title: Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 19990601
Title: Rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy.
Journal: The American journal of cardiology 19990401
Title: Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha.
Journal: Thrombosis and haemostasis 19981201
Title: [Acute hepatitis caused by gemfibrozil].
Journal: Gastroenterologia y hepatologia 19981001
Title: Atorvastatin and gemfibrozil metabolites, but not the parent drugs, are potent antioxidants against lipoprotein oxidation.
Journal: Atherosclerosis 19980601
Title: Effects of two different fibric acid derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in type IIb hyperlipoproteinaemia.
Journal: Atherosclerosis 19980501
Title: [Gemfibrozil induced impotence].
Journal: Anales de medicina interna (Madrid, Spain : 1984) 19980301
Title: Clinical pharmacokinetics of fibric acid derivatives (fibrates).
Journal: Clinical pharmacokinetics 19980201
Title: Rhabdomyolysis associated with simvastatin-gemfibrozil therapy.
Journal: Southern medical journal 19970501
Title: Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.
Journal: Toxicology and applied pharmacology 19970101
Title: Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey.
Journal: Arteriosclerosis, thrombosis, and vascular biology 19970101
Title: A head-to-head comparison of the cost effectiveness of HMG-CoA reductase inhibitors and fibrates in different types of primary hyperlipidemia.
Journal: Cardiovascular drugs and therapy 19970101
Title: Peroxisome proliferators alter the expression of estrogen-metabolizing enzymes.
Journal: Biochimie 19970101
Title: Opposite effects of bezafibrate and gemfibrozil in both normal and hypertriglyceridemic rats.
Journal: Atherosclerosis 19961115
Title: The effects of gemfibrozil upon the hypercoagulable state in dyslipidaemic patients with chronic renal failure.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19961101
Title: Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19960903
Title: Hepatotumorigenicity and peroxisome proliferation induced by the hypolipidemic CI-924 in a two-year study in male and female B6C3F1 mice.
Journal: Toxicologic pathology 19960101
Title: Rhabdomyolysis and acute renal failure associated with gemfibrozil therapy.
Journal: Nephron 19960101
Title: Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.
Journal: Journal of lipid research 19951201
Title: Gemfibrozil-induced peroxisome proliferation and hepatomegaly in male F344 rats.
Journal: Cancer letters 19951106
Title: Currently available hypolipidaemic drugs and future therapeutic developments.
Journal: Bailliere's clinical endocrinology and metabolism 19951001
Title: Spondylitis-like and symmetric polyarthralgia associated with gemfibrozil therapy.
Journal: British journal of rheumatology 19950701
Title: Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates: relationship with peroxisome proliferation.
Journal: British journal of pharmacology 19950401
Title: Gemfibrozil induced myositis: a case report with light microscopic and ultrastructural study.
Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 19940601
Title: [Gemfibrozil-induced myopathy].
Journal: Harefuah 19931101
Title: Rhabdomyolysis and renal failure secondary to combination therapy of hyperlipidemia with lovastatin and gemfibozil.
Journal: Connecticut medicine 19930901
Title: Acute compartment syndrome: an unusual presentation of gemfibrozil induced myositis.
Journal: The Medical journal of Australia 19930104
Title: Gemfibrozil-induced impotence.
Journal: The Annals of pharmacotherapy 19930101
Title: Vasculitis, Raynaud's phenomenon and polyarthritis associated with gemfibrozil therapy.
Journal: British journal of rheumatology 19930101
Title: Mechanism of action of fibrates.
Journal: Postgraduate medical journal 19930101
Title: Sexual dysfunction after gemfibrozil.
Journal: BMJ (Clinical research ed.) 19920919
Title: Gemfibrozil-lovastatin therapy for primary hyperlipoproteinemias.
Journal: The American journal of cardiology 19920701
Title: Lovastatin/gemfibrozil myopathy: a clinical, histochemical, and ultrastructural study.
Journal: European neurology 19920101
Title: Gemfibrozil-induced myopathy.
Journal: Archives of internal medicine 19910901
Title: Cholesterol-lowering agent myopathy (CLAM).
Journal: Neurology 19910701
Title: Rhabdomyolysis with simvastatin use.
Journal: Nephron 19910101
Title: Effects of gemfibrozil and other fibric acid derivatives on blood lipids and lipoproteins.
Journal: Journal of clinical pharmacology 19910101
Title: Gemfibrozil-induced impotence.
Journal: Lancet (London, England) 19901103
Title: Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy.
Journal: JAMA 19900704
Title: Rhabdomyolysis and acute renal failure induced by combination lovastatin and gemfibrozil therapy.
Journal: Annals of internal medicine 19900201
Title: [Headache caused by gemfibrozil].
Journal: Medicina clinica 19900120
Title: Treatment of heterozygous familial hypercholesterolemia with lipid-lowering drugs.
Journal: Arteriosclerosis (Dallas, Tex.) 19890101
Title: Gemfibrozil-induced headache.
Journal: Lancet (London, England) 19881126
Title: HMG CoA reductase inhibitors. Current clinical experience.
Journal: Drugs 19880101
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