Home Amines 267402-71-1
267402-71-1,MFCD02683596
Catalog No.:AA00C2TJ

267402-71-1 | 9-Isopropyl-N2,N6-bis(4-methoxybenzyl)-9H-purine-2,6-diamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$14.00   $10.00
- +
5mg
98%
in stock  
$33.00   $23.00
- +
10mg
98%
in stock  
$39.00   $28.00
- +
25mg
98%
in stock  
$70.00   $49.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C2TJ
Chemical Name:
9-Isopropyl-N2,N6-bis(4-methoxybenzyl)-9H-purine-2,6-diamine
CAS Number:
267402-71-1
Molecular Formula:
C24H28N6O2
Molecular Weight:
432.5181
MDL Number:
MFCD02683596
SMILES:
COc1ccc(cc1)CNc1nc(NCc2ccc(cc2)OC)c2c(n1)n(cn2)C(C)C
Properties
Properties
 
Form:
Solid  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
551  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
9  
XLogP3:
4.3  

Literature

Title: Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives.

Journal: Bioorganic & medicinal chemistry 20090501

Title: Myoseverin disrupts sarcomeric organization in myocytes: an effect independent of microtubule assembly inhibition.

Journal: Cell motility and the cytoskeleton 20080101

Title: Evaluation of novel microtubules interfering agents myoseverin, tubulyzine and E2GG in primary cultures of rat hepatocytes.

Journal: General physiology and biophysics 20070901

Title: Synthesis and biological activity of 8-azapurine and pyrazolo[4,3-d]pyrimidine analogues of myoseverin.

Journal: European journal of medicinal chemistry 20061201

Title: Myoseverin is a potential angiogenesis inhibitor by inhibiting endothelial cell function and endothelial progenitor cell differentiation.

Journal: DNA and cell biology 20060901

Title: Small molecules driving myotube fission.

Journal: Chemistry & biology 20051001

Title: A single-cell analysis of myogenic dedifferentiation induced by small molecules.

Journal: Chemistry & biology 20051001

Title: A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening.

Journal: Journal of the American Chemical Society 20021002

Title: Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors.

Journal: Chemistry & biology 20020401

Title: Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors.

Journal: Journal of medicinal chemistry 20011220

Title: Rosania GR, et al. Myoseverin, a microtubule-binding molecule with novel cellular effects. Nat Biotechnol. 2000;18(3):304-308.

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Tags:267402-71-1 Molecular Formula|267402-71-1 MDL|267402-71-1 SMILES|267402-71-1 9-Isopropyl-N2,N6-bis(4-methoxybenzyl)-9H-purine-2,6-diamine