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27665-39-0,MFCD26743658
Catalog No.:AA002UAF

27665-39-0 | Butane-1,4-disulfonic acid hydrate

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Purity
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1g
97%
in stock  
$29.00   $20.00
- +
5g
98-102%(T),(contains 30-40%H2O)
in stock  
$33.00   $23.00
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25g
97%
in stock  
$94.00   $66.00
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100g
97%
in stock  
$326.00   $228.00
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500g
97%
in stock  
$1,407.00   $985.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002UAF
Chemical Name:
Butane-1,4-disulfonic acid hydrate
CAS Number:
27665-39-0
Molecular Formula:
C4H10O6S2
Molecular Weight:
218.2486
MDL Number:
MFCD26743658
SMILES:
OS(=O)(=O)CCCCS(=O)(=O)O
Properties
Properties
 
Form:
Solid  
MP:
84℃  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
266  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
-1.3  

Downstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,2010,vol.132,p.14603-14616

[2]Patent:CN104086463,2016,B.Locationinpatent:Paragraph0030;0031;0032

641571-10-0    27665-39-0   
4-methyl-N-3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl-3-4-(3-pyridinyl)-2-pyrimidinylaminobenzamide1,4-butanedisulphonate 

[1]Patent:WO2016/24289,2016,A2.Locationinpatent:Page/Pagecolumn7

[1]CurrentPatentAssignee:HAISCOPHARMACEUTICALGROUPCO.,LTD.-CN107759568,2018,ALocationinpatent:Paragraph0440;0441;0448;0449;0450;0451

Literature

Title: Changes in IL12A methylation pattern in livers from mice fed DDC.

Journal: Experimental and molecular pathology 20120401

Title: Two cationic metal-organic frameworks based on cadmium and α,ω-alkanedisulfonate anions and their photoluminescent properties.

Journal: Dalton transactions (Cambridge, England : 2003) 20101214

Title: Discrepancy in response and remission rates for SAMe-treated patients in a double-blind, randomized clinical trial.

Journal: The American journal of psychiatry 20101201

Title: Using complementary and alternative medicines for depression.

Journal: The Journal of clinical psychiatry 20100901

Title: Genomic and epigenomic instability, fragile sites, schizophrenia and autism.

Journal: Current genomics 20100901

Title: S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial.

Journal: The American journal of psychiatry 20100801

Title: S-adenosyl methionine (SAMe) augmentation in major depressive disorder.

Journal: The American journal of psychiatry 20100801

Title: Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants.

Journal: The Journal of clinical psychiatry 20100601

Title: Oxidative stress and the pathogenesis of cholestasis.

Journal: Seminars in liver disease 20100501

Title: Evaluation of phospholipid and liposomal S-adenosyl methionine for the treatment of liver injury in a murine model.

Journal: Journal of pharmaceutical sciences 20100401

Title: Chronic hypothyroidism only marginally affects adult-type Leydig cell regeneration after EDS administration.

Journal: International journal of andrology 20100201

Title: Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. V. Complementary and alternative medicine treatments.

Journal: Journal of affective disorders 20091001

Title: Alternative treatments in pediatric bipolar disorder.

Journal: Child and adolescent psychiatric clinics of North America 20090401

Title: Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies.

Journal: Toxicology and applied pharmacology 20090215

Title: Liposome dependent delivery of S-adenosyl methionine to cells by liposomes: a potential treatment for liver disease.

Journal: Journal of pharmaceutical sciences 20090201

Title: Complementary and alternative medicine for perinatal depression.

Journal: Journal of affective disorders 20090101

Title: Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice.

Journal: Laboratory investigation; a journal of technical methods and pathology 20081001

Title: Complementary and alternative medicine in the treatment of bipolar disorder--a review of the evidence.

Journal: Journal of affective disorders 20080901

Title: Are nutritional supplements ready for prime time?

Journal: The Journal of clinical psychiatry 20080901

Title: Comparison of S-adenosyl-L-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose.

Journal: Toxicology 20080203

Title: INSLF3-LGR8 ligand-receptor system in testes of mature rats after exposure to ethane dimethanesulphonate (short communication).

Journal: Folia medica 20080101

Title: c-erbAalpha and c-erbaAbeta in the Leydig cell repopulation by ethane-1,2-dimethanesulphonate model of mature rats.

Journal: Folia medica 20080101

Title: Nutraceuticals in the management of osteoarthritis.

Journal: Orthopedics 20070801

Title: [Determination of 1, 4-butanedisulphonate by IEC with suppressed conductivity detection].

Journal: Se pu = Chinese journal of chromatography 20060901

Title: Therapy of NAFLD: antioxidants and cytoprotective agents.

Journal: Journal of clinical gastroenterology 20060301

Title: Evaluation of the influence of S-adenosylmethionine on systemic and hepatic effects of prednisolone in dogs.

Journal: American journal of veterinary research 20050201

Title: Nonpharmacologic treatments for depression in patients with coronary heart disease.

Journal: Psychosomatic medicine 20050101

Title: The effects of S-adenosylmethionine on clinical pathology and redox potential in the red blood cell, liver, and bile of clinically normal cats.

Journal: Journal of veterinary internal medicine 20050101

Title: S-adenosyl-L-methionine (SAMe) as an adjunct for resistant major depressive disorder: an open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine.

Journal: Journal of clinical psychopharmacology 20041201

Title: Evaluation of relative role of LH and FSH in restoration of spermatogenesis using ethanedimethylsulphonate-treated adult rats.

Journal: Reproductive biomedicine online 20040201

Title: S-adenosyl-methionine in depression: a comprehensive review of the literature.

Journal: Current psychiatry reports 20031201

Title: RXRalpha-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity.

Journal: Experimental and molecular pathology 20031201

Title: A double-blind, randomized parallel-group, efficacy and safety study of intramuscular S-adenosyl-L-methionine 1,4-butanedisulphonate (SAMe) versus imipramine in patients with major depressive disorder.

Journal: The international journal of neuropsychopharmacology 20021201

Title: S-adenosylmethionine and cAMP confer differential cytoprotection against bile acid-induced apoptosis in canine renal tubular cells and primary rat hepatocytes.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20020101

Title: Developmental and hormonal regulation of type II DNA topoisomerase in rat testis.

Journal: Journal of molecular endocrinology 20010601

Title: Differential expression of CCAAT/enhancer-binding protein-delta (c/EBPdelta) in rat androgen-dependent tissues and human prostate cancer.

Journal: Journal of andrology 20010101

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Tags:27665-39-0 Molecular Formula|27665-39-0 MDL|27665-39-0 SMILES|27665-39-0 Butane-1,4-disulfonic acid hydrate