29331-92-8 | 10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

36507-30-9    29331-92-8 

[1]Patent:WO2013/167985,2013,A1,.Locationinpatent:Paragraph00102;00103

[2]Patent:US2016/122332,2016,A1,.Locationinpatent:Paragraph0123-0124

[3]Patent:WO2006/75925,2006,A2,.Locationinpatent:Page/Pagecolumn9-10

[4]BioorganicandMedicinalChemistry,2014,vol.22,#3,p.1077-1088

791633-38-0    29331-92-8 

[1]Patent:EP1477480,2004,A1,.Locationinpatent:Page6,7

[2]Patent:EP1477480,2004,A1,.Locationinpatent:Page6

28721-07-5    29331-92-8 

[1]Patent:CN106588773,2017,A,.Locationinpatent:Paragraph0093;0094;0095;0096

[2]Patent:US2016/122332,2016,A1,.Locationinpatent:Paragraph0137-0138

[3]Patent:WO2013/8194,2013,A2,.Locationinpatent:Page/Pagecolumn12;13

[4]Patent:US2015/65704,2015,A1,.Locationinpatent:Paragraph0072

[5]JournalofMedicinalChemistry,1999,vol.42,#14,p.2582-2587

[6]RSCAdvances,2016,vol.6,#101,p.98730-98736

[7]Patent:WO2010/113179,2010,A2,.Locationinpatent:Page/Pagecolumn13

[8]Patent:WO2011/91131,2011,A2,.Locationinpatent:Page/Pagecolumn39

[9]Patent:WO2011/138795,2011,A2,.Locationinpatent:Page/Pagecolumn22

[10]Patent:WO2012/121701,2012,A1,.Locationinpatent:Page/Pagecolumn13

[11]Patent:CN106938986,2017,A,.Locationinpatent:Paragraph0028;0029;0034;0035;0036

356760-08-2    29331-92-8 

[1]Patent:WO2006/53674,2006,A2,.Locationinpatent:Page/Pagecolumn6

[2]Patent:US2008/221320,2008,A1,.Locationinpatent:Page/Pagecolumn2

[3]Patent:WO2006/53674,2006,A2,.Locationinpatent:Page/Pagecolumn6

[4]Patent:US2008/221320,2008,A1,.Locationinpatent:Page/Pagecolumn2

[5]Patent:WO2006/53674,2006,A2,.Locationinpatent:Page/Pagecolumn5-6

[6]Patent:US2008/221320,2008,A1,.Locationinpatent:Page/Pagecolumn2

[7]Patent:WO2006/53674,2006,A2,.Locationinpatent:Page/Pagecolumn2-5

[8]Patent:WO2006/53674,2006,A2,.Locationinpatent:Page/Pagecolumn4-5

[9]Patent:WO2006/53674,2006,A2,.Locationinpatent:Page/Pagecolumn5

[10]Patent:US2008/221320,2008,A1,.Locationinpatent:Page/Pagecolumn1-2

[11]Patent:US2008/221320,2008,A1,.Locationinpatent:Page/Pagecolumn2

[12]Patent:US2008/221320,2008,A1,.Locationinpatent:Page/Pagecolumn2

3564-73-6    28721-07-5    29331-92-8 

[1]EuropeanJournalofOrganicChemistry,2003,#3,p.578-586

3564-73-6    29331-92-8 

[1]Bioscience,BiotechnologyandBiochemistry,1993,vol.57,p.1589-1590

59-67-6    29331-92-8   

nicotinicacid5-carbamoyl-10,11-dihydro-5<i>H</i>-dibenzo<i>b</i>,<i>f</i>azepin-10-ylester 

[1]JournalofMedicinalChemistry,1999,vol.42,p.2582-2587

104-01-8    29331-92-8   

(4-methoxy-phenyl)-aceticacid5-carbamoyl-10,11-dihydro-5<i>H</i>-dibenzo<i>b</i>,<i>f</i>azepin-10-ylester 

[1]JournalofMedicinalChemistry,1999,vol.42,p.2582-2587

28721-07-5    29331-92-8 

[1]Patent:CN106588773,2017,A.Locationinpatent:Paragraph0093;0094;0095;0096

[2]Patent:US2016/122332,2016,A1.Locationinpatent:Paragraph0137-0138

[3]Patent:WO2013/8194,2013,A2.Locationinpatent:Page/Pagecolumn12;13

[4]Patent:US2015/65704,2015,A1.Locationinpatent:Paragraph0072

[5]JournalofMedicinalChemistry,1999,vol.42,p.2582-2587

[6]RSCAdvances,2016,vol.6,p.98730-98736

[7]Patent:WO2010/113179,2010,A2.Locationinpatent:Page/Pagecolumn13

[8]Patent:WO2011/91131,2011,A2.Locationinpatent:Page/Pagecolumn39

[9]Patent:WO2011/138795,2011,A2.Locationinpatent:Page/Pagecolumn22

[10]Patent:WO2012/121701,2012,A1.Locationinpatent:Page/Pagecolumn13

[11]Patent:CN106938986,2017,A.Locationinpatent:Paragraph0028;0029;0034;0035;0036

29331-92-8    13734-41-3   

2-<i>tert</i>-butoxycarbonylamino-3-methyl-butyricacid5-carbamoyl-10,11-dihydro-5<i>H</i>-dibenzo<i>b</i>,<i>f</i>azepin-10-ylester 

[1]JournalofMedicinalChemistry,1999,vol.42,p.2582-2587

Title: A chiral liquid chromatography method for the simultaneous determination of oxcarbazepine, eslicarbazepine, R-licarbazepine and other new chemical derivatives BIA 2-024, BIA 2-059 and BIA 2-265, in mouse plasma and brain.

Journal: Biomedical chromatography : BMC 20120301

Title: Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures.

Journal: Epilepsy research 20110901

Title: Development and validation of an enantioselective liquid-chromatography/tandem mass spectrometry method for the separation and quantification of eslicarbazepine acetate, eslicarbazepine, R-licarbazepine and oxcarbazepine in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110901

Title: Pharmacokinetics of the monohydroxy derivative of oxcarbazepine and its enantiomers after a single intravenous dose given as racemate compared with a single oral dose of oxcarbazepine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601

Title: Drug resistance in epilepsy and the ABCB1 gene: The clinical perspective.

Journal: Indian journal of human genetics 20110501

Title: Development of liquid chromatographic enantiomer separation methods and validation for the estimation of (R)-enantiomer in eslicarbazepine acetate.

Journal: Journal of pharmaceutical and biomedical analysis 20110105

Title: Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify novel receptor binders and putative valvulopathic compounds among common drugs.

Journal: Journal of medicinal chemistry 20101111

Title: Binding of licarbazepine enantiomers to mouse and human plasma proteins.

Journal: Biopharmaceutics & drug disposition 20100701

Title: Development and validation of an HPLC-UV method for the simultaneous quantification of carbamazepine, oxcarbazepine, eslicarbazepine acetate and their main metabolites in human plasma.

Journal: Analytical and bioanalytical chemistry 20100601

Title: Eyeblink conditioning anomalies in bipolar disorder suggest cerebellar dysfunction.

Journal: Bipolar disorders 20090201

Title: Stereoselective disposition of S- and R-licarbazepine in mice.

Journal: Chirality 20080601

Title: Pharmacokinetics of licarbazepine in healthy volunteers: single and multiple oral doses and effect of food.

Journal: Journal of clinical pharmacology 20080501

Title: Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection.

Journal: Analytica chimica acta 20070716

Title: A novel enantioselective microassay for the high-performance liquid chromatography determination of oxcarbazepine and its active metabolite monohydroxycarbazepine in human plasma.

Journal: Therapeutic drug monitoring 20070601

Title: Drug monitoring and toxicology: a procedure for the monitoring of oxcarbazepine metabolite by HPLC-UV.

Journal: Journal of chromatographic science 20060101

Title: Simultaneous liquid chromatographic determination of lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in plasma of patients with epilepsy.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051215

Title: A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine.

Journal: Epilepsia 20051001

Title: Safety, tolerability, and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humans.

Journal: Journal of clinical pharmacology 20040801

Title: Overview of the clinical pharmacokinetics of oxcarbazepine.

Journal: Clinical drug investigation 20040101

Title: Assessment of the bioequivalence of two oxcarbazepine oral suspensions versus a film-coated tablet in healthy subjects.

Journal: International journal of clinical pharmacology and therapeutics 20030701

Title: Oxcarbazepine final market image tablet formulation bioequivalence study after single administration and at steady state in healthy subjects.

Journal: International journal of clinical pharmacology and therapeutics 20021101

Title: Suppressive effects of oxcarbazepine on tooth pulp-evoked potentials recorded at the trigeminal spinal tract nucleus in cats.

Journal: Clinical and experimental pharmacology & physiology 20010301