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312-93-6,MFCD00152787
Catalog No.:AA00BC6Q

312-93-6 | DEXAMETHASONE SODIUM PHOSPHATE

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25mg
3 weeks  
$378.00   $264.00
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100mg
3 weeks  
$595.00   $416.00
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500mg
3 weeks  
$2,125.00   $1,487.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BC6Q
Chemical Name:
DEXAMETHASONE SODIUM PHOSPHATE
CAS Number:
312-93-6
Molecular Formula:
C22H30FO8P
Molecular Weight:
472.4410
MDL Number:
MFCD00152787
SMILES:
O=C1C=C[C@]2(C(=C1)CC[C@@H]1[C@]2(F)[C@@H](O)C[C@]2([C@H]1C[C@H]([C@]2(O)C(=O)COP(=O)(O)O)C)C)C
Properties
Computed Properties
 
Complexity:
973  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
0.1  

Literature

Title: An in vitro approach for prioritization and evaluation of chemical effects on glucocorticoid receptor mediated adipogenesis.

Journal: Toxicology and applied pharmacology 20180915

Title: Glucocorticoids exert direct toxicity on microvasculature: analysis of cell death mechanisms.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150201

Title: Non-invasive monitoring of glucocorticoid metabolites in banded mongooses (Mungos mungo) in response to physiological and biological challenges.

Journal: General and comparative endocrinology 20121101

Title: Swimming exercise ameliorates depression-like behaviors induced by prenatal exposure to glucocorticoids in rats.

Journal: Neuroscience letters 20120830

Title: Extrusion printed polymer structures: a facile and versatile approach to tailored drug delivery platforms.

Journal: International journal of pharmaceutics 20120117

Title: Acute glucocorticoid administration rapidly suppresses basal and stress-induced hypothalamo-pituitary-adrenal axis activity.

Journal: Endocrinology 20120101

Title: Determination of the particulate size and aggregation of clonidine and corticosteroids for epidural steroid injection.

Journal: Pain physician 20120101

Title: Selective targeting of disease-relevant protein binding domains by O-phosphorylated natural product derivatives.

Journal: ACS chemical biology 20111021

Title: Effect of menthol on ocular drug delivery.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20111001

Title: [Therapy-refractory overactive bladder: alternative treatment approaches].

Journal: Der Urologe. Ausg. A 20110701

Title: Evaluation of the toxicity of triamcinolone acetonide and dexamethasone sodium phosphate on human lens epithelial cells (HLE B-3).

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110601

Title: Modulation of the foreign body reaction for implants in the subcutaneous space: microdialysis probes as localized drug delivery/sampling devices.

Journal: Journal of diabetes science and technology 20110501

Title: Determination of dexamethasone and dexamethasone sodium phosphate in human plasma and cochlear perilymph by liquid chromatography/tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110101

Title: Stability of ondansetron and dexamethasone infusion upon refrigeration.

Journal: The Annals of pharmacotherapy 20110101

Title: Effects of clarithromycin and dexamethasone on mucus production in isografted rat trachea.

Journal: Pharmacology 20110101

Title: Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6.

Journal: Journal of neuroinflammation 20110101

Title: Oxidative stress in the developing brain: effects of postnatal glucocorticoid therapy and antioxidants in the rat.

Journal: PloS one 20110101

Title: Incidence of plantar fascia ruptures following corticosteroid injection.

Journal: Foot & ankle specialist 20101201

Title: The adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment.

Journal: Acta physiologica (Oxford, England) 20101101

Title: Effect of topical glucocorticoid treatment in chinchilla model of lipopolysaccharide induced otitis media with effusion.

Journal: International journal of pediatric otorhinolaryngology 20101101

Title: Trans-scleral iontophoretic delivery of low molecular weight therapeutics.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20101015

Title: Aprepitant use in children, adolescents, and young adults for the control of chemotherapy-induced nausea and vomiting (CINV).

Journal: Journal of pediatric hematology/oncology 20101001

Title: Subconjunctival mycetoma as an unusual cause of tears with black deposits.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20101001

Title: Fentanyl pretreatment for alleviation of perineal symptoms following preoperative administration of intravenous dexamethasone sodium phosphate--a prospective, randomized, double blind, placebo controlled study.

Journal: Middle East journal of anaesthesiology 20101001

Title: A pH-sensitive molecularly imprinted nanospheres/hydrogel composite as a coating for implantable biosensors.

Journal: Biomaterials 20100601

Title: Extended delivery of hydrophilic drugs from silicone-hydrogel contact lenses containing vitamin E diffusion barriers.

Journal: Biomaterials 20100501

Title: Antioxidant treatment alters peripheral vascular dysfunction induced by postnatal glucocorticoid therapy in rats.

Journal: PloS one 20100101

Title: In vivo native fluorescence spectroscopy and nicotinamide adinine dinucleotide/flavin adenine dinucleotide reduction and oxidation states of oral submucous fibrosis for chemopreventive drug monitoring.

Journal: Journal of biomedical optics 20100101

Title: Liposomal encapsulation enhances and prolongs the anti-inflammatory effects of water-soluble dexamethasone phosphate in experimental adjuvant arthritis.

Journal: Arthritis research & therapy 20100101

Title: Drug packaging and delivery using perfluorocarbon nanoparticles for targeted inhibition of vascular smooth muscle cells.

Journal: Acta pharmacologica Sinica 20091101

Title: Intra-arterial injection in the rat brain: evaluation of steroids used for transforaminal epidurals.

Journal: Spine 20090715

Title: Acute tumor lysis syndrome in a hemodialysis patient with diffuse large B cell lymphoma.

Journal: Medical oncology (Northwood, London, England) 20090101

Title: Effects of anabolic and therapeutic doses of dexamethasone on thymus morphology and apoptosis in veal calves.

Journal: The Veterinary record 20081011

Title: The effect of otic vehicle and concentration of dexamethasone on liver enzyme activities and adrenal function in small breed healthy dogs.

Journal: Veterinary dermatology 20080801

Title: Antitumor activity and tumor localization of liposomal glucocorticoids in B16 melanoma-bearing mice.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20080421

Title: Different substances and dry-needling injections in patients with myofascial pain and headaches.

Journal: Cranio : the journal of craniomandibular practice 20080401

Title: Size and aggregation of corticosteroids used for epidural injections.

Journal: Pain medicine (Malden, Mass.) 20080301

Title: Cardiovascular expression of inflammatory signaling molecules, the kinin B1 receptor and COX2, in the rabbit: effects of LPS, anti-inflammatory and anti-hypertensive drugs.

Journal: Regulatory peptides 20080207

Title: Masseter cysticercosis - a rare case diagnosed on ultrasound.

Journal: Dento maxillo facial radiology 20080201

Title: Drug incorporation and release of water soluble drugs from novel functionalized poly(glycerol adipate) nanoparticles.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20080104

Title: A comparative study of treatment for brain edema: magnesium sulphate versus dexamethasone sodium phosphate.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20080101

Title: Electromotive drug administration for treatment of therapy-refractory overactive bladder.

Journal: International braz j urol : official journal of the Brazilian Society of Urology 20080101

Title: Dexamethasone sodium phosphate-loaded Chitosan based delivery systems for buccal application.

Journal: Journal of drug targeting 20071101

Title: Regulation of tissue beta-adrenergic, glucocorticoid and androgen receptors induced by repeated exposure to growth promoters in male veal calves.

Journal: Research in veterinary science 20071001

Title: [Preliminary study on brain-targeted drug delivery via inner ear].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20071001

Title: Saliva, an alternative biologic matrix to detect glucocorticoid treatment in calves: experimental contribution.

Journal: Veterinary research communications 20070801

Title: Quantification of dexamethasone and corticosterone in rat biofluids and fetal tissue using highly sensitive analytical methods: assay validation and application to a pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20070601

Title: Long-term treatment with autologous red blood cells loaded with dexamethasone 21-phosphate in pediatric patients affected by steroid-dependent Crohn disease.

Journal: Journal of pediatric gastroenterology and nutrition 20070401

Title: Comparison of the particle sizes of different steroids and the effect of dilution: a review of the relative neurotoxicities of the steroids.

Journal: Anesthesiology 20070201

Title: Effects of experimental immunosuppression in cattle with persistently high antibody levels to Salmonella Dublin lipopolysaccharide O-antigens.

Journal: BMC veterinary research 20070101

Title: The effect of intense, short-term topical dexamethasone disodium phosphate eyedrops on blood glucose level in diabetic patients.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20070101

Title: A topical nitric oxide-releasing dexamethasone derivative: effects on intraocular pressure and ocular haemodynamics in a rabbit glaucoma model.

Journal: The British journal of ophthalmology 20061101

Title: Hyperglycemia after repeated periocular dexamethasone injections in patients with diabetes.

Journal: Ophthalmology 20061001

Title: A case of calcific retropharyngeal tendinitis suspected to be a retropharyngeal abscess upon the first medical examination.

Journal: Auris, nasus, larynx 20060901

Title: Maintenance rituximab following induction chemoimmunotherapy may prolong progression-free survival in mantle cell lymphoma: a pilot study from the Wisconsin Oncology Network.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20060901

Title: RAT CYP3A and CYP2B1/2 were not associated with nevirapine-induced hepatotoxicity.

Journal: Methods and findings in experimental and clinical pharmacology 20060901

Title: Selective targeting of liposomes to macrophages using a ligand with high affinity for the macrophage scavenger receptor class A.

Journal: Current drug discovery technologies 20060601

Title: Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis.

Journal: Arthritis and rheumatism 20060401

Title: Neonatal dexamethasone and chronic tianeptine treatment inhibit ligature-induced periodontitis in adult rats.

Journal: Journal of periodontal research 20060201

Title: A pilot trial on safety and efficacy of erythrocyte-mediated steroid treatment in CF patients.

Journal: BMC pediatrics 20060101

Title: Compatibility and stability of dexamethasone sodium phosphate and ketamine hydrochloride subcutaneous infusions in polypropylene syringes.

Journal: Journal of pain and symptom management 20050701

Title: Effects of low-dose dexamethasone on thymus morphology and immunological parameters in veal calves.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20050501

Title: A comparative study of the action of dexamethasone sodium phosphate and dexamethasone acetate in steroid-eluting pacemaker leads.

Journal: Pacing and clinical electrophysiology : PACE 20050401

Title: Thyroid hormone, but not parathyroid hormone, partially restores glucocorticoid-induced growth retardation.

Journal: Pediatric nephrology (Berlin, Germany) 20050301

Title: Zone-specific cell proliferation during compensatory adrenal growth in rats.

Journal: American journal of physiology. Endocrinology and metabolism 20050201

Title: Evaluation of effect of some corticosteroids on glucose-6-phosphate dehydrogenase and comparative study of antioxidant enzyme activities.

Journal: Journal of enzyme inhibition and medicinal chemistry 20050201

Title: ['Restricted ablation' of elongated uvula mucosa by the injection of the ethanol/steroid mixture: a new treatment for snoring and OSAS].

Journal: Nihon Jibiinkoka Gakkai kaiho 20050101

Title: Comparison of topical steroids for acute anterior uveitis.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20041201

Title: Effect of corticosteroid on salicylate-induced morphological changes of isolated cochlear outer hair cells.

Journal: The Annals of otology, rhinology, and laryngology 20040901

Title: The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma.

Journal: Respiratory research 20040101

Title: Failure of intravitreal dexamethasone to diminish inflammation or retinal toxicity in an experimental model of Bacillus cereus endophthalmitis.

Journal: Current eye research 20040101

Title: Induction of apoptosis in nasal polyp fibroblasts by glucocorticoids in vitro.

Journal: Acta oto-laryngologica 20031201

Title: Visual deterioration in giant cell arteritis patients while on high doses of corticosteroid therapy.

Journal: Ophthalmology 20030601

Title: Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability.

Journal: The Journal of clinical endocrinology and metabolism 20030101

Title: Dexamethasone-induced apoptosis in immune cells from peripheral circulation and lymphomyeloid tissues of juvenile clearnose skates, Raja eglanteria.

Journal: Developmental and comparative immunology 20020901

Title: Utility of nuclear magnetic resonance spectroscopy to characterize the structure of dexamethasone sodium phosphate inclusion complexes with cyclodextrins in solution and to analyze potential competitive effects.

Journal: Journal of pharmaceutical sciences 20020601

Title: Trace determination of dexamethasone sodium phosphate in pharmaceutical formulations by differential pulse polarography.

Journal: Analytical and bioanalytical chemistry 20020401

Title: Subtenon's depot corticosteroid injections in patients with a history of corticosteroid-induced intraocular pressure elevation.

Journal: American journal of ophthalmology 20020201

Title: Physical compatibility and in vivo evaluation of drug mixtures for subcutaneous infusion to cancer patients in palliative care.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20020101

Title: In vivo biocompatibility of gelatin-based hydrogels and interpenetrating networks.

Journal: Journal of biomaterials science. Polymer edition 20020101

Title: Supratarsal injection of corticosteroids in the treatment of refractory vernal keratoconjunctivitis.

Journal: Indian journal of ophthalmology 20011201

Title: Comparison of 0.1% dexamethasone phosphate eye gel (Dexagel) and 1% prednisolone acetate eye suspension in the treatment of post-operative inflammation after cataract surgery.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20011001

Title: Corticosteroid and antibiotic therapy for bacillus endophthalmitis.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20010901

Title: Effects of topical unoprostone and latanoprost on acute and recurrent herpetic keratitis in the rabbit.

Journal: American journal of ophthalmology 20010501

Title: [Dexamethasone Sodium Phosphate Reference Standard (Control 001) of National Institute of Health Sciences].

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20010101

Title: Increased intraocular pressure during treatment for chronic uveitis.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 19970401

Title: Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 19960801

Title: Drug-induced, life-threatening angioedema revisited.

Journal: The Laryngoscope 19930101

Title: Angioedema from angiotensin converting enzyme inhibitors: a cause of upper airway obstruction.

Journal: The Laryngoscope 19901101

Title: Effect of folinic acid on the capacity of trimethoprim-sulfamethoxazole to prevent and treat Pneumocystis carinii pneumonia in rats.

Journal: Antimicrobial agents and chemotherapy 19860201

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Tags:312-93-6 Molecular Formula|312-93-6 MDL|312-93-6 SMILES|312-93-6 DEXAMETHASONE SODIUM PHOSPHATE