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39562-70-4,MFCD00082255
Catalog No.:AA003T25

39562-70-4 | Nitrendipine

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10mg
98%
in stock  
$6.00   $4.00
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50mg
98%
in stock  
$7.00   $5.00
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250mg
98%
in stock  
$13.00   $9.00
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1g
98%
in stock  
$29.00   $21.00
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5g
98%
in stock  
$91.00   $64.00
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25g
98%
in stock  
$318.00   $223.00
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100g
98%(HPLC)
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$1,191.00   $834.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003T25
Chemical Name:
Nitrendipine
CAS Number:
39562-70-4
Molecular Formula:
C18H20N2O6
Molecular Weight:
360.3612
MDL Number:
MFCD00082255
SMILES:
CCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1)[N+](=O)[O-])C(=O)OC)C
NSC Number:
758466
Properties
Properties
 
BP:
464.8°C at 760 mmHg  
Form:
Solid  
MP:
1580C  
Refractive Index:
1.5700 (estimate)  
Solubility:
methanol: 15 mg/mL  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
661  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.9  

Literature

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Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601

Title: Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.

Journal: Scientific reports 20140101

Title: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions 20130905

Title: Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.

Journal: Pharmacological research 20121001

Title: Involvement of basal and calcium-activated protein kinase C in neurotransmitter secretion in mouse motor synapses.

Journal: Bulletin of experimental biology and medicine 20121001

Title: A novel image analysis methodology for online monitoring of nucleation and crystal growth during solid state phase transformations.

Journal: International journal of pharmaceutics 20120820

Title: Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815

Title: Effect of pomegranate juice on intestinal transport and pharmacokinetics of nitrendipine in rats.

Journal: Phytotherapy research : PTR 20120801

Title: Facilitation of neurotransmitter release in mouse motor synapses in different modes of protein kinase C activation.

Journal: Bulletin of experimental biology and medicine 20120801

Title: The development of a novel dry powder inhaler.

Journal: International journal of pharmaceutics 20120715

Title: A novel surface modified nitrendipine nanocrystals with enhancement of bioavailability and stability.

Journal: International journal of pharmaceutics 20120701

Title: Effect of pomegranate juice on the pharmacokinetics of nitrendipine in rabbits.

Journal: European journal of drug metabolism and pharmacokinetics 20120601

Title: Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.

Journal: Bioorganic & medicinal chemistry letters 20120115

Title: PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans.

Journal: Nature genetics 20120115

Title: Polymer-mediated anti-solvent crystallization of nitrendipine: monodispersed spherical crystals and growth mechanism.

Journal: Pharmaceutical research 20120101

Title: Development of a LC-ESI-MS3 method for determination of nitrendipine in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20111215

Title: Nitrendipine nanocrystals: its preparation, characterization, and in vitro-in vivo evaluation.

Journal: AAPS PharmSciTech 20111201

Title: Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

Title: A potential calcium antagonist and its antihypertensive effects.

Journal: Fitoterapia 20111001

Title: Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.

Journal: Cardiovascular research 20110701

Title: Influence of dihydropyridine calcium antagonist nitrendipine on benzo(a)pyrene-induced oxidative stress.

Journal: Archives of pharmacal research 20110701

Title: Differences in crystallization rate of nitrendipine enantiomers in amorphous solid dispersions with HPMC and HPMCP.

Journal: International journal of pharmaceutics 20110404

Title: Preparation and characterization of nitrendipine solid lipid nanoparticles.

Journal: Die Pharmazie 20110301

Title: Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier.

Journal: Molecular medicine (Cambridge, Mass.) 20110101

Title: Ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of nitrendipine in dog plasma and its application to a pharmacokinetic study of a solid self-emulsifying pellet formulation.

Journal: Arzneimittel-Forschung 20110101

Title: Redox modulation of diaphragm contractility: Interaction between DHPR and RyR channels.

Journal: Free radical biology & medicine 20101215

Title: Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201

Title: Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.

Journal: Bioorganic & medicinal chemistry 20101115

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships.

Journal: Bioorganic & medicinal chemistry 20101101

Title: Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells.

Journal: Neurochemistry international 20101001

Title: Prevention of hypertensive crises in rats induced by acute and chronic norepinephrine excess.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20101001

Title: [Isolated systolic hypertension threatens the heart and the brain. Fixed combination optimizes blood pressure control and offers clear prognostic advantage].

Journal: MMW Fortschritte der Medizin 20100902

Title: Effect of crystal size on the in vitro dissolution and oral absorption of nitrendipine in rats.

Journal: Pharmaceutical research 20100901

Title: Inhibition of contractions of nerve processes in calcium-free medium.

Journal: Bulletin of experimental biology and medicine 20100801

Title: Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.

Journal: Journal of medicinal chemistry 20100722

Title: Preparation of stable nitrendipine nanosuspensions using the precipitation-ultrasonication method for enhancement of dissolution and oral bioavailability.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100711

Title: Ca(2+) channel blocker benidipine promotes coronary angiogenesis and reduces both left-ventricular diastolic stiffness and mortality in hypertensive rats.

Journal: Journal of hypertension 20100701

Title: Amino acid sensing by enteroendocrine STC-1 cells: role of the Na+-coupled neutral amino acid transporter 2.

Journal: American journal of physiology. Cell physiology 20100601

Title: Synthesis, vasorelaxant activity and antihypertensive effect of benzo[d]imidazole derivatives.

Journal: Bioorganic & medicinal chemistry 20100601

Title: Collision type and player anticipation affect head impact severity among youth ice hockey players.

Journal: Pediatrics 20100601

Title: Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.

Journal: Bioorganic & medicinal chemistry 20100501

Title: Sphingosine kinase inhibition alleviates endothelial permeability induced by thrombin and activated neutrophils.

Journal: Shock (Augusta, Ga.) 20100401

Title: Morbidity and mortality on combination versus monotherapy: a posthoc analysis of the Systolic Hypertension in Europe trial.

Journal: Journal of hypertension 20100401

Title: Imaging and analysis of evoked excitatory-postsynaptic-calcium-transients by individual presynaptic-boutons of cultured Aplysia sensorimotor synapse.

Journal: Cell calcium 20100401

Title: [Analysis of therapeutic effects of rural patients with hypertension by combination administration of low dosage of hydrochlorothiazide and nitrendipine].

Journal: Zhonghua xin xue guan bing za zhi 20100201

Title: Solid self-emulsifying nitrendipine pellets: preparation and in vitro/in vivo evaluation.

Journal: International journal of pharmaceutics 20100104

Title: Development of ultra fast liquid chromatographic method for simultaneous determination of nitrendipine and carvone in skin diffusate samples.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery.

Journal: The European respiratory journal 20091201

Title: LTD and LTP at the developing retinogeniculate synapse.

Journal: Journal of neurophysiology 20091201

Title: Formulation and evaluation of monolithic matrix polymer films for transdermal delivery of nitrendipine.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20091201

Title: Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats.

Journal: European journal of pharmacology 20091012

Title: Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.

Journal: Bioorganic & medicinal chemistry 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells.

Journal: Anesthesia and analgesia 20091001

Title: [Isolated systolic hypertension].

Journal: MMW Fortschritte der Medizin 20090910

Title: Cost-utility analysis of eprosartan compared to enalapril in primary prevention and nitrendipine in secondary prevention in Europe--the HEALTH model.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090901

Title: T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.

Journal: Circulation 20090901

Title: Effect of metformin on weight gain during antihypertensive treatment with a beta-blocker in Chinese patients.

Journal: American journal of hypertension 20090801

Title: The role of calcium influx pathways in phospholipase D activation in bovine adrenal glomerulosa cells.

Journal: The Journal of endocrinology 20090701

Title: Direct enhancement of presynaptic calcium influx in presynaptic facilitation at Aplysia sensorimotor synapses.

Journal: Molecular and cellular neurosciences 20090601

Title: Angiotensin receptor blockers and secondary stroke prevention: the MOSES study.

Journal: Expert review of cardiovascular therapy 20090501

Title: Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms.

Journal: Molecular pharmacology 20090201

Title: Development and evaluation of nitrendipine nanoemulsion for intranasal delivery.

Journal: Journal of biomedical nanotechnology 20090201

Title: Development of SLN and NLC enriched hydrogels for transdermal delivery of nitrendipine: in vitro and in vivo characteristics.

Journal: Drug development and industrial pharmacy 20090101

Title: Post-hypoxic changes in rat cortical neuron GABA A receptor function require L-type voltage-gated calcium channel activation.

Journal: Neuropharmacology 20090101

Title: Effectiveness and tolerability of fixed-dose combination enalapril plus nitrendipine in hypertensive patients: results of the 3-month observational, post-marketing, multicentre, prospective CENIT study.

Journal: Clinical drug investigation 20090101

Title: Design, development, physicochemical, in vitro and in vivo evaluation of monolithic matrix type transdermal patches containing nitrendipine.

Journal: Pharmaceutical development and technology 20090101

Title: Eprosartan: a review of its use in hypertension.

Journal: Drugs 20090101

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: The effect of penetration enhancers on permeation kinetics of nitrendipine in two different skin models.

Journal: Biological & pharmaceutical bulletin 20080901

Title: Differential contribution of L-, N-, and P/Q-type calcium channels to [Ca2+]i changes evoked by kainate in hippocampal neurons.

Journal: Neurochemical research 20080801

Title: [Combined drug therapy is better: successfully protecting elderly hypertensive patients].

Journal: MMW Fortschritte der Medizin 20080731

Title: Development of nitrendipine controlled release formulations based on SLN and NLC for topical delivery: in vitro and ex vivo characterization.

Journal: Drug development and industrial pharmacy 20080701

Title: Calcium entry inhibition during resuscitation from shock attenuates inflammatory lung injury.

Journal: Shock (Augusta, Ga.) 20080701

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.

Journal: Nature chemical biology 20080501

Title: Functional subtypes of renal alpha1-adrenoceptor in diabetic and non-diabetic 2K1C Goldblatt renovascular hypertension.

Journal: Acta pharmacologica Sinica 20080501

Title: Protective effect of melatonin on Ca2+ homeostasis and contractility in acute cholecystitis.

Journal: Journal of pineal research 20080401

Title: Application of a self-modeling curve resolution method for studying the photodegradation kinetics of nitrendipine and felodipine.

Journal: Journal of pharmaceutical and biomedical analysis 20080213

Title: Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers.

Journal: British journal of pharmacology 20080101

Title: Alpha1A- and alpha1D-adrenoceptors are the major functional subtypes of renal alpha1-adrenoceptors in streptozotocin-induced diabetic and normal Sprague-Dawley rats.

Journal: Autonomic & autacoid pharmacology 20080101

Title: Quantitative determination of nitrendipine in human plasma using high-performance liquid chromatography-mass spectrometry.

Journal: Arzneimittel-Forschung 20080101

Title: Sublingual application of liquid nitrendipine does not result in critical hypotension in healthy volunteers under phosphodiesterase-5 inhibition.

Journal: Clinical hemorheology and microcirculation 20080101

Title: Participation of different types of voltage-dependent calcium channels in evoked quantal transmitter release in frog neuromuscular junctions.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20080101

Title: Influence of some bioflavonoids on the transport of nitrendipine.

Journal: Drug metabolism and drug interactions 20080101

Title: Systolic blood pressure reduction with olmesartan medoxomil versus nitrendipine in elderly patients with isolated systolic hypertension.

Journal: Journal of hypertension 20071001

Title: [Study on skin toxicology and penetration enhancement of skin absorption of volatile oil extracted from tender branchers of Camellia oleifera].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

Title: Improvement of the dissolution rate of nitrendipine using a new pulse combustion drying method.

Journal: Chemical & pharmaceutical bulletin 20070801

Title: CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons.

Journal: Neuropharmacology 20070601

Title: Crystallization rate of amorphous nifedipine analogues unrelated to the glass transition temperature.

Journal: International journal of pharmaceutics 20070504

Title: Development and evaluation of nitrendipine loaded solid lipid nanoparticles: influence of wax and glyceride lipids on plasma pharmacokinetics.

Journal: International journal of pharmaceutics 20070420

Title: Effect of chronic hypoxia on voltage-independent calcium influx activated by 5-HT in rat intrapulmonary arteries.

Journal: Pflugers Archiv : European journal of physiology 20070401

Title: Development and validation of a reversed-phase HPLC method for determination of nitrendipine in rat plasma: application to pharmacokinetic studies.

Journal: Biomedical chromatography : BMC 20070401

Title: Differential effects of dihydropyridine calcium antagonists on doxorubicin-induced nephrotoxicity in rats.

Journal: Toxicology 20070227

Title: Dihydropyridines inhibit acetylcholine-induced hyperpolarization in cochlear artery via blockade of intermediate-conductance calcium-activated potassium channels.

Journal: The Journal of pharmacology and experimental therapeutics 20070201

Title: Development of nitrendipine transdermal patches: in vitro and ex vivo characterization.

Journal: Current drug delivery 20070101

Title: Circadian blood pressure variation and antihypertensive medication adjustment in normoalbuminuric type 2 diabetes patients.

Journal: Kidney & blood pressure research 20070101

Title: Adjunctive treatment with moxonidine versus nitrendipine for hypertensive patients with advanced renal failure: a cost-effectiveness analysis.

Journal: BMC nephrology 20070101

Title: Synergism of hydrochlorothiazide and nitrendipine on reduction of blood pressure and blood pressure variability in spontaneously hypertensive rats.

Journal: Acta pharmacologica Sinica 20061201

Title: Cardiorenal protective effects of year-long antihypertensive therapy with an angiotensin-converting enzyme inhibitor or a calcium channel blocker in spontaneously hypertensive rats.

Journal: American journal of hypertension 20061201

Title: Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration.

Journal: Journal of drug targeting 20061101

Title: Paradoxical nifedipine facilitation of 45Ca uptake into rat hippocampal synaptosomes.

Journal: European journal of pharmacology 20060821

Title: [Not all antihypertensive agents protect equally well].

Journal: MMW Fortschritte der Medizin 20060817

Title: Tolerance to the antinociceptive effects of ethanol during ethanol withdrawal.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20060701

Title: [Emergency checklist in hypertensive crisis].

Journal: MMW Fortschritte der Medizin 20060622

Title: E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils.

Journal: Blood 20060615

Title: Does the MOSES study provide sufficient evidence for Eprosartan against Nitrendipine?

Journal: Stroke 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Sustained beta-adrenergic stimulation increased L-type Ca2+ channel expression in cultured quiescent ventricular myocytes.

Journal: The journal of physiological sciences : JPS 20060401

Title: A case of type 2 diabetes mellitus developing hypothyroidism discovered as a result of a discrepancy between glycated hemoglobin and glycated albumin values.

Journal: Diabetes research and clinical practice 20060301

Title: The novel application of tertiary butyl alcohol in the preparation of hydrophobic drug-HPbetaCD complex.

Journal: The Journal of pharmacy and pharmacology 20060301

Title: Effects of eprosartan on target organ protection.

Journal: Vascular health and risk management 20060301

Title: Morbidity and mortality after stroke--eprosartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES).

Journal: Stroke 20060201

Title: MOSES raises questions.

Journal: Stroke 20060201

Title: MOSES: superiority or noninferiority?

Journal: Stroke 20060201

Title: Changes in guinea pig gallbladder smooth muscle Ca2+ homeostasis by acute acalculous cholecystitis.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20060101

Title: Preparation and evaluation of solid dispersions of nitrendipine prepared with fine silica particles using the melt-mixing method.

Journal: Chemical & pharmaceutical bulletin 20060101

Title: Mechanism of increased alpha-adrenoceptor-mediated contraction in small resistance arteries of rats with heart failure.

Journal: Clinical and experimental pharmacology & physiology 20060101

Title: Determination of nifedipine in serum of women in preterm labor by high-performance liquid chromatography with diode array detection.

Journal: Journal of AOAC International 20060101

Title: Preventing cerebrovascular and cardiovascular events after stroke: eprosartan or nitrendipine?

Journal: Nature clinical practice. Neurology 20060101

Title: Thermal stability of 1,4-dihydropyridine derivatives in solid state.

Journal: Acta poloniae pharmaceutica 20060101

Title: BCRP transports dipyridamole and is inhibited by calcium channel blockers.

Journal: Pharmaceutical research 20051201

Title: Predicting the anti-hypertensive effect of nitrendipine from plasma concentration profiles using artificial neural networks.

Journal: Computers in biology and medicine 20051201

Title: Mechanism of D(2) agonist-induced inhibition of GH secretion from human GH-secreting adenoma cells.

Journal: Endocrine journal 20051201

Title: Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051109

Title: Preparation and evaluation of solid dispersion for nitrendipine-carbopol and nitrendipine-HPMCP systems using a twin screw extruder.

Journal: Chemical & pharmaceutical bulletin 20051001

Title: [Double blind study of the efficacy and safety of the fixed dose combination of enalapril 10 mg/nitrendipine 20 mg versus the increase of amlopidine dose in essential hypertensive patients not controlled with amlodipine 5 mg].

Journal: Revista clinica espanola 20050901

Title: Analysis of recent papers in hypertension. An angiotensin receptor blocker is more effective than a calcium channel blocker in secondary stroke prevention.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20050801

Title: In vivo evaluation of two novel controlled-release nitrendipine formulations.

Journal: Drug development and industrial pharmacy 20050801

Title: Store-operated calcium channel inhibition attenuates neutrophil function and postshock acute lung injury.

Journal: The Journal of trauma 20050701

Title: Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo.

Journal: Neuroscience letters 20050603

Title: Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES).

Journal: Stroke 20050601

Title: Thyroid hormone export from cells: contribution of P-glycoprotein.

Journal: The Journal of endocrinology 20050401

Title: [Hypotensive effectiveness of therapy combined enalapril and nitrendipine and influence on the quality of life].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050301

Title: Localization of intracellular calcium release in cells injured by venom from the ectoparasitoid Nasonia vitripennis (Walker) (Hymenoptera: Pteromalidae) and dependence of calcium mobilization on G-protein activation.

Journal: Journal of insect physiology 20050201

Title: Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats.

Journal: Journal of hypertension 20050101

Title: Eprosartan (Teveten) offers new opportunities to prevent a second stroke.

Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20050101

Title: [Toxicological analysis of selected 1,4-dihydropyridine calcium channel blockers in the diagnosis of intoxications].

Journal: Archiwum medycyny sadowej i kryminologii 20050101

Title: Azelnidipine, a dihydropyridine-based calcium antagonist, inhibits angiotensin II-induced oxidative stress generation and downregulation of pigment epithelium-derived factor mRNA levels in microvascular endothelial cells.

Journal: Drugs under experimental and clinical research 20050101

Title: Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats.

Journal: Die Pharmazie 20041201

Title: A novel pH-dependent gradient-release delivery system for nitrendipine II. Investigations of the factors affecting the release behaviors of the system.

Journal: International journal of pharmaceutics 20041122

Title: Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20041101

Title: The role of existing and newer calcium channel blockers in the treatment of hypertension.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20041101

Title: Prognostic significance of electrocardiographic voltages and their serial changes in elderly with systolic hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20041001

Title: Isoflurane reduces the carbachol-evoked Ca2+ influx in neuronal cells.

Journal: Anesthesiology 20041001

Title: Circadian and cAMP-dependent modulation of retinal cone cGMP-gated channels does not require protein synthesis or calcium influx through L-type channels.

Journal: Brain research 20040924

Title: Effects of nitrendipine on reference and working memory of rats in three-panel runway.

Journal: Pharmacological research 20040901

Title: Calcium channel blockers ameliorate disease in a mouse model of multiple sclerosis.

Journal: Experimental neurology 20040901

Title: [Evaluation of in vitro/in vivo correlation for three kinds of self-designed sustained-release nitrendipine formulations using deconvolution method].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040901

Title: A novel pH-dependent gradient-release delivery system for nitrendipine: I. Manufacturing, evaluation in vitro and bioavailability in healthy dogs.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20040811

Title: Regulation of ion channel localization and phosphorylation by neuronal activity.

Journal: Nature neuroscience 20040701

Title: [Effects of nitrendipine on circadian variation of blood pressure in inpatients with renal parenchymal hypertension: assessment by ambulatory blood pressure monitoring].

Journal: Nihon Jinzo Gakkai shi 20040701

Title: The contribution of adrenoceptor subtype(s) in the renal vasculature of diabetic spontaneously hypertensive rats.

Journal: British journal of pharmacology 20040601

Title: Effects of Li+ transport and intracellular binding on Li+/Mg2+ competition in bovine chromaffin cells.

Journal: Biochimica et biophysica acta 20040503

Title: Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.

Journal: Journal of hypertension 20040401

Title: Comparison of the antihypertensive effects of the fixed dose combination enalapril 10 mg/nitrendipine 20 mg vs losartan 50 mg/hydrochlorothiazide 12.5 mg, assessed by 24-h ambulatory blood pressure monitoring, in essential hypertensive patients.

Journal: Journal of human hypertension 20040301

Title: Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.

Journal: Pharmaceutical research 20040301

Title: Two useful methods for evaluating antihypertensive drugs in conscious freely moving rats.

Journal: Acta pharmacologica Sinica 20040201

Title: ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.

Journal: The Journal of endocrinology 20040101

Title: Inhibition of type A GABA receptors by L-type calcium channel blockers.

Journal: Neuroscience 20040101

Title: Pharmacology of the human red cell voltage-dependent cation channel; Part I. Activation by clotrimazole and analogues.

Journal: Blood cells, molecules & diseases 20040101

Title: Fixed-dose combination enalapril/nitrendipine: a review of its use in mild-to-moderate hypertension.

Journal: Drugs 20040101

Title: Analysis of phenomena involved in the apical growth of Phycomyces blakesleeanus.

Journal: Archives of microbiology 20031201

Title: Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201

Title: Ca2+ influx does not trigger glucose-induced traffic of the insulin granules and alteration of their distribution.

Journal: Experimental biology and medicine (Maywood, N.J.) 20031101

Title: Improvement of dissolution and bioavailability of nitrendipine by inclusion in hydroxypropyl-beta-cyclodextrin.

Journal: Drug development and industrial pharmacy 20031101

Title: Contribution of blood pressure variability to the effect of nitrendipine on end-organ damage in spontaneously hypertensive rats.

Journal: Journal of hypertension 20031001

Title: Design of sustained-release nitrendipine microspheres having solid dispersion structure by quasi-emulsion solvent diffusion method.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030904

Title: Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.

Journal: Pflugers Archiv : European journal of physiology 20030901

Title: Moxonidine treatment of hypertensive patients with advanced renal failure.

Journal: Journal of hypertension 20030901

Title: [Effect of losartan and Nitrendipine on fibrinolytic system in patient with essential hypertensim].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20030901

Title: [Most hypertensive patients need drug combination treatment. 'First line therapy is in second place'].

Journal: MMW Fortschritte der Medizin 20030821

Title: Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.

Journal: Bioorganic & medicinal chemistry letters 20030818

Title: [Preparation of sustained-release nitrendipine microspheres with a solid dispersed structure in liquid system].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20030801

Title: Nitrendipine and amlodipine mimic the acute effects of enalapril on renal haemodynamics and reduce glomerular hyperfiltration in patients with chronic kidney disease.

Journal: Journal of human hypertension 20030701

Title: Preparation of sustained-release nitrendipine microspheres with Eudragit RS and Aerosil using quasi-emulsion solvent diffusion method.

Journal: International journal of pharmaceutics 20030618

Title: Effect of nitric oxide releasing drugs on the intensity of infection during experimental trichinellosis in mice.

Journal: Parasitology research 20030601

Title: High-performance liquid chromatographic analysis of nitrendipine in human plasma using ultraviolet detection and single-step solid-phase sample preparation.

Journal: Journal of pharmaceutical and biomedical analysis 20030601

Title: [When hypertension becomes an emergency case: lower the blood pressure, but slowly!].

Journal: MMW Fortschritte der Medizin 20030529

Title: [Hypertensive patients have to be doubly treated earlier. Which antihypertensive drug combination is appropriate to whom?].

Journal: MMW Fortschritte der Medizin 20030529

Title: Inflammation, arteriosclerosis, and cardiovascular therapy in hemodialysis patients.

Journal: Kidney international. Supplement 20030501

Title: Enhanced interleukin-4 production in CD4+ T cells and elevated immunoglobulin E levels in antigen-primed mice by bisphenol A and nonylphenol, endocrine disruptors: involvement of nuclear factor-AT and Ca2+.

Journal: Immunology 20030501

Title: Calcium-channel blockers may prevent dementia.

Journal: Harvard health letter 20030501

Title: [A new antihypertensive drug. Successful duo now as fixed combination].

Journal: MMW Fortschritte der Medizin 20030213

Title: Amplification of sumatriptan-induced contraction in rabbit saphenous vein but not in basilar artery.

Journal: American journal of physiology. Heart and circulatory physiology 20030201

Title: Modulation of ACh release by presynaptic muscarinic autoreceptors in the neuromuscular junction of the newborn and adult rat.

Journal: The European journal of neuroscience 20030101

Title: Acrylate-based transdermal therapeutic system of nitrendipine.

Journal: Drug development and industrial pharmacy 20030101

Title: [Cognitive decline and hypertension].

Journal: Archives des maladies du coeur et des vaisseaux 20030101

Title: Nitrendipine-induced subacute cutaneous lupus erythematosus.

Journal: European journal of dermatology : EJD 20030101

Title: [Theoretical model of a cost-effectiveness analysis of combined enalapril-nitrendipine therapy for treating hypertension].

Journal: Atencion primaria 20030101

Title: Influence of nifedipine, nitrendipine and verapamil at low concentration on antipyrine metabolism examined by extracorporeal rat liver perfusion.

Journal: Polish journal of pharmacology 20030101

Title: [Syst-Eur study: analysis of the benefits of nitrendipine in hypertensive type 2 diabetics].

Journal: Archives des maladies du coeur et des vaisseaux 20030101

Title: Effect of combination therapy with a calcium channel blocker and an angiotensin-converting enzyme inhibitor on renal hypertrophy and urinary albumin excretion in diabetic rats.

Journal: Experimental diabesity research 20030101

Title: Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.

Journal: British journal of pharmacology 20021201

Title: Importance of blood pressure variability in organ protection in spontaneously hypertensive rats treated with combination of nitrendipine and atenolol.

Journal: Acta pharmacologica Sinica 20021201

Title: The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study.

Journal: Archives of internal medicine 20021014

Title: Drotaverine interacts with the L-type Ca(2+) channel in pregnant rat uterine membranes.

Journal: European journal of pharmacology 20020802

Title: Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020801

Title: L-type calcium channel-mediated plateau potentials in barrelette cells during structural plasticity.

Journal: Journal of neurophysiology 20020801

Title: Inhibitors of phosphatidylinositol 3-kinase amplify insulin release from islets of lean but not obese mice.

Journal: The Journal of endocrinology 20020801

Title: Nitrendipine blocks the nociceptive effects of chronically administered ethanol.

Journal: Alcoholism, clinical and experimental research 20020801

Title: Effect of amyotrophic lateral sclerosis serum on calcium channels related to spontaneous acetylcholine release.

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20020701

Title: Mechanism of angiotensin II-induced phospholipase D activation in bovine adrenal glomerulosa cells.

Journal: Molecular and cellular endocrinology 20020628

Title: Hydrolytic degradation of nitrendipine and nisoldipine.

Journal: Journal of pharmaceutical and biomedical analysis 20020601

Title: Microemulsion formulation for enhanced absorption of poorly soluble drugs. II. In vivo study.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20020517

Title: Hyposmotic shock stimulates insulin secretion by two distinct mechanisms. Studies with the betaHC9 cell.

Journal: American journal of physiology. Endocrinology and metabolism 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020301

Title: Synaptic mechanisms regulating the activation of a Ca(2+)-mediated plateau potential in developing relay cells of the LGN.

Journal: Journal of neurophysiology 20020301

Title: Paradoxical release of nitric oxide by an L-type calcium channel antagonist, the R+ enantiomer of amlodipine.

Journal: Journal of cardiovascular pharmacology 20020201

Title: Enalapril/nitrendipine. ENEAS, nitrendipine/enalapril.

Journal: Drugs in R&D 20020101

Title: Synaptic plasticity in the trigeminal principal nucleus during the period of barrelette formation and consolidation.

Journal: Brain research. Developmental brain research 20011214

Title: [Innovation, step innovation, Me too. Are calcium antagonists interchangeable?].

Journal: MMW Fortschritte der Medizin 20011213

Title: Nitrendipine and enalapril combination therapy in mild to moderate hypertension: assessment of dose-response relationship by a clinical trial of factorial design.

Journal: Journal of cardiovascular pharmacology 20011201

Title: Effect of bile acids on absorption of nitrendipine in healthy subjects.

Journal: British journal of clinical pharmacology 20011201

Title: Quantitative determination of nitrendipine and its metabolite dehydronitrendipine in human plasma using liquid chromatography-tandem mass spectrometry.

Journal: Biomedical chromatography : BMC 20011201

Title: Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe Trial.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20011201

Title: The use of calcium blockers to study biochemical behaviour of Saccharomyces cerevisiae cells.

Journal: Molecular and cellular biochemistry 20011201

Title: Involvement of calcium, inositol-1,4,5 trisphosphate and diacylglycerol in the prothoracicotropic hormone-stimulated ecdysteroid synthesis and secretion in the prothoracic glands of Bombyx mori.

Journal: Zoological science 20011201

Title: Bending the MDCK cell primary cilium increases intracellular calcium.

Journal: The Journal of membrane biology 20011101

Title: Applications of liquid chromatography-tandem mass spectrometry in drug and biomedical analyses.

Journal: Clinica chimica acta; international journal of clinical chemistry 20011101

Title: Risk and benefit of treatment of isolated systolic hypertension in the elderly: evidence from the Systolic Hypertension in Europe Trial.

Journal: Current opinion in cardiology 20011101

Title: Independent modulation of L-type Ca2+ channel in guinea pig ventricular cells by nitrendipine and isoproterenol.

Journal: Japanese heart journal 20011101

Title: Do arterial effects of antihypertensive drugs depend on subject's serum cholesterol?

Journal: Journal of cardiovascular pharmacology 20011001

Title: A double-blind trial of perindopril and nitrendipine in incipient diabetic nephropathy.

Journal: Diabetes, nutrition & metabolism 20011001

Title: Parathyroid hormone-stimulated resorption in calvaria cultured in serum-free medium is enhanced by the calcium-mobilizing activity of 1,25-dihydroxyvitamin D(3).

Journal: Bone 20010901

Title: Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815

Title: Calcium channels in Xenopus spinal neurons differ in somas and presynaptic terminals.

Journal: Journal of neurophysiology 20010701

Title: Effect of quinapril versus nitrendipine on endothelial dysfunction in patients with systemic hypertension.

Journal: The American journal of cardiology 20010615

Title: Effect of angiotensin II on calcium reabsorption by the luminal membranes of the nephron.

Journal: American journal of physiology. Endocrinology and metabolism 20010601

Title: Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.

Journal: The European journal of neuroscience 20010601

Title: [Hypertensive crisis, hypertensive emergency. Nitrate spray and ambulance--this can also be wrong].

Journal: MMW Fortschritte der Medizin 20010517

Title: Mechanism of action of the calcium-sensing receptor in human antral gastrin cells.

Journal: Gastroenterology 20010401

Title: Prognostic significance of serum creatinine and uric acid in older Chinese patients with isolated systolic hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20010401

Title: Effects of calcium channel blockers on pentylenetetrazol drug discrimination in rats.

Journal: Alcohol (Fayetteville, N.Y.) 20010401

Title: The relevance of nitrendipine erythrocyte partitioning for the variability of its bioavailability parameters.

Journal: International journal of pharmaceutics 20010314

Title: Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis.

Journal: Journal of pharmaceutical and biomedical analysis 20010301

Title: Characterization of secretory and morphologic properties of primary cultured endocrine cells from porcine pancreata.

Journal: Pancreas 20010301

Title: Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.

Journal: Journal of hypertension 20010301

Title: Coupling of L-type calcium channels to neurotransmitter release at mouse motor nerve terminals.

Journal: Pflugers Archiv : European journal of physiology 20010301

Title: [Effect of combination of ligustrazine and nitrendipine on hemodynamics in patients with chronic obstructive pulmonary disease].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010301

Title: Oxidative degradation study of nitrendipine using stability indicating, HPLC, HPTLC and spectrophotometric method.

Journal: Journal of pharmaceutical and biomedical analysis 20010201

Title: Vatanidipine hydrochloride: a new long-lasting antihypertensive agent.

Journal: Expert opinion on investigational drugs 20010101

Title: Calcium channels coupled to neurotransmitter release at dually innervated neuromuscular junctions in the newborn rat.

Journal: Neuroscience 20010101

Title: The influence of chloroethylclonidine-induced contraction in isolated arteries of Wistar Kyoto rats: alpha1D- and alpha1A-adrenoceptors, protein kinase C, and calcium influx.

Journal: Archives of medical research 20010101

Title: Computer-aided measurement of cell shortening and calcium transients in adult cardiac myocytes.

Journal: Biotechnology progress 20010101

Title: [Therapeutic mechanism of combination therapy of ligustrazine and nitrendipine in treating patients with chronic obstructive pulmonary disease].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010101

Title: Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20000705

Title: Haloperidol-induced catalepsy is influenced by calcium channel antagonists.

Journal: Acta poloniae pharmaceutica 20000101

Title: Effects of the calcium antagonists verapamil and nitrendipine on carbamazepine withdrawal.

Journal: Methods and findings in experimental and clinical pharmacology 19991201

Title: Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.

Journal: The American journal of physiology 19980901

Title: The novel insulinotropic mechanism of pimobendan: direct enhancement of the exocytotic process of insulin secretory granules by increased Ca2+ sensitivity in beta-cells.

Journal: Endocrinology 19980301

Title: Evaluation of the efficacy and tolerability of nitrendipine in reducing both pressure and left ventricular mass in hypertensive type 2 diabetic patients.

Journal: Diabetes care 19970801

Title: L-type calcium channels regulate gastrin release from human antral G cells.

Journal: The American journal of physiology 19970801

Title: Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of perindopril and nitrendipine on arterial stiffness in hypertensive individuals.

Journal: Hypertension (Dallas, Tex. : 1979) 19961201

Title: Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.

Journal: Journal of medicinal chemistry 19960719

Title: Nitrendipine and enalapril improve albuminuria and glomerular filtration rate in non-insulin dependent diabetes.

Journal: Kidney international. Supplement 19960601

Title: Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19960301

Title: Antihypertensive effects of trandolapril and nitrendipine in the elderly: a controlled trial with special emphasis on time effect profiles.

Journal: Journal of human hypertension 19960101

Title: Differences between haloperidol- and pimozide-induced withdrawal syndrome: a role for Ca2+ channels.

Journal: European journal of pharmacology 19951229

Title: Effect of indomethacin on blood pressure control during treatment with nitrendipine.

Journal: Blood pressure 19950901

Title: Delayed development of hypertension after short-term nitrendipine treatment.

Journal: Hypertension (Dallas, Tex. : 1979) 19940701

Title: Doxazosin versus nitrendipine: a double-blind comparative study in patients adhering to a sodium-restricted diet.

Journal: Cardiovascular drugs and therapy 19940601

Title: Treatment of hypertensive emergency. Comparison of a new dosage form of the calcium antagonist nitrendipine with nifedipine capsules.

Journal: Intensive care medicine 19940101

Title: Combination treatment of enalapril with nitrendipine in rats with renovascular hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 19940101

Title: Nocturnal hypotension and ACE inhibitors.

Journal: Journal of human hypertension 19930601

Title: Arterial and antihypertensive effects of nitrendipine: a double-blind comparison versus placebo.

Journal: Journal of cardiovascular pharmacology 19921201

Title: Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 19920801

Title: BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu), is a non-competitive antagonist of the actions of endothelin-1 in SK-N-MC human neuroblastoma cells.

Journal: Biochemical and biophysical research communications 19920415

Title: Effect of antihypertensive treatment with nitrendipine on left ventricular mass and diastolic filling in patients with mild to moderate hypertension.

Journal: Journal of cardiovascular pharmacology 19920101

Title: Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 19920101

Title: Pharmacokinetics, bioavailability, metabolism and acute and chronic antihypertensive effects of nitrendipine in patients with chronic renal failure and moderate to severe hypertension.

Journal: British journal of clinical pharmacology 19910301

Title: The place of isradipine in the treatment of hypertension.

Journal: American journal of hypertension 19910201

Title: Microvascular effects of cocaine; interaction with nitrendipine and enalaprilat.

Journal: Journal of toxicology. Clinical toxicology 19910101

Title: Tolerance to nitrendipine in patients with arterial hypertension accompanying chronic renal failure.

Journal: Journal of cardiovascular pharmacology 19910101

Title: Regression of cardiovascular structural changes after long-term antihypertensive treatment with the calcium antagonist nitrendipine.

Journal: Journal of cardiovascular pharmacology 19910101

Title: Acute and short-term effects of nitrendipine and diltiazem at rest and during exercise in hypertensive patients.

Journal: Clinical therapeutics 19910101

Title: Nitrendipine decreases benzodiazepine withdrawal seizures but not the development of benzodiazepine tolerance or withdrawal signs.

Journal: British journal of pharmacology 19901101

Title: Lacidipine: a calcium antagonist with potent and long-lasting antihypertensive effects in animal studies.

Journal: Journal of cardiovascular pharmacology 19900401

Title: Systemic and regional hemodynamic interactions of perindopril and nitrendipine in the spontaneously hypertensive rat.

Journal: Journal of cardiovascular pharmacology 19900401

Title: Effects of nitrendipine and atenolol on blood pressure and intracellular sodium in hypertensive blacks.

Journal: Journal of human hypertension 19900401

Title: Preclinical pharmacology of Ro 31-6930, a new potassium channel opener.

Journal: Journal of cardiovascular pharmacology 19900201

Title: Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats.

Journal: Life sciences 19900101

Title: [The effect of calcium antagonist nitrendipine on the morphological picture of experimentally-produced myocardial injuries in rats].

Journal: Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie 19900101

Title: Cardiovascular-risk reduction: initial diuretic therapy compared with calcium-antagonist (felodipine) therapy for primary hypertension.

Journal: The Medical journal of Australia 19890904

Title: Cocaine-induced small vessel spasm in isolated rat hearts.

Journal: The American journal of pathology 19890701

Title: Nitrendipine versus hydrochlorothiazide in hypertensive patients over 70 years of age.

Journal: Clinical pharmacology and therapeutics 19890301

Title: Cosecretion of calcitonin and calcitonin gene-related peptide from cultured rat medullary thyroid C cells.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19890201

Title: Treatment of hypertension in the elderly with a new calcium channel blocking drug, nitrendipine.

Journal: The American journal of medicine 19890101

Title: Felodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.

Journal: Drugs 19881001

Title: Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy.

Journal: Journal of cardiovascular pharmacology 19880701

Title: Calcium currents in embryonic and neonatal mammalian skeletal muscle.

Journal: The Journal of general physiology 19880601

Title: Effects of nitrendipine and cilazapril alone or in combination on hemodynamics and regional blood flows in conscious spontaneously hypertensive rats.

Journal: Journal of cardiovascular pharmacology 19880101

Title: Short- and long-term cerebrovascular effects of nitrendipine in hypertensive patients.

Journal: Journal of cardiovascular pharmacology 19880101

Title: A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.

Journal: European journal of clinical pharmacology 19880101

Title: Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications.

Journal: Journal of clinical pharmacology 19871101

Title: Catecholamines, renin-angiotensin-aldosterone, and cardiovascular response during exercise following acute and long-term calcium antagonism with felodipine in essential hypertension.

Journal: Journal of cardiovascular pharmacology 19871001

Title: MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia.

Journal: Journal of cardiovascular pharmacology 19870701

Title: Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals.

Journal: Arzneimittel-Forschung 19870401

Title: Renal effects of 1,4-dihydropyridines in animal models of hypertension and renal failure.

Journal: Journal of cardiovascular pharmacology 19870101

Title: Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension.

Journal: Journal of cardiovascular pharmacology 19870101

Title: Felodipine, a new calcium antagonist, as monotherapy in mild or moderate hypertension. Cooperative study group.

Journal: Drugs 19870101

Title: Baroreflex control of renin release in spontaneously hypertensive rats after administration of felodipine.

Journal: Drugs 19870101

Title: Felodipine compared to nifedipine as 'third-line drug' in resistant hypertension.

Journal: Angiology 19861101

Title: Alteration of left ventricular diastolic filling in hypertensive patients: effects of nitrendipine and atenolol.

Journal: European heart journal 19860901

Title: Relative potency of a beta-blocking and a calcium entry blocking agent as antihypertensive drugs in black patients.

Journal: European journal of clinical pharmacology 19860101

Title: Predictors of blood pressure increases after withdrawal of antihypertensive therapy.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19851201

Title: The protective effect of nitrendipine on gentamicin acute renal failure in rats.

Journal: Experimental and molecular pathology 19850801

Title: Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.

Journal: Journal of cardiovascular pharmacology 19850101

Title: Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19841001

Title: Clinical and systemic hemodynamic effects of nitrendipine.

Journal: Clinical pharmacology and therapeutics 19840601

Title: Mode of antihypertensive action of nitrendipine.

Journal: Journal of cardiovascular pharmacology 19840101

Title: Systemic and regional hemodynamics in normotensive and spontaneously hypertensive rats after slow-channel calcium blocker nitrendipine.

Journal: Clinical and experimental hypertension. Part A, Theory and practice 19840101

Title: S Kazda, et al. Diuretic effect of nitrendipine contributes to its antihypertensive efficacy: a review. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S1-5.

Title: M Bursztyn, et al. Nitrendipine improves glucose tolerance and deoxyglucose uptake in hypertensive rats. Hypertension. 1994 Jun;23(6 Pt 2):1051-3.

Title: He-Hui Xie, et al. Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats. J Hypertens. 2005 Jan;23(1):193-201.

Title: Bellemann, P., et al., H-Nitrendipine, a potent calcium antagonist, binds with high affinity to cardiac membranes. Arzneimittelforschung, 1981. 31(12): p. 2064-7.

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Tags:39562-70-4 Molecular Formula|39562-70-4 MDL|39562-70-4 SMILES|39562-70-4 Nitrendipine