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4037-01-8,MFCD00167482
Catalog No.:AA019FRR

4037-01-8 | ACTH (4-10)

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1mg
≥95%
in stock  
$104.00   $73.00
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2mg
≥95%
in stock  
$134.00   $94.00
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5mg
≥95%
in stock  
$216.00   $152.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA019FRR
Chemical Name:
ACTH (4-10)
CAS Number:
4037-01-8
Molecular Formula:
C44H59N13O10S
Molecular Weight:
962.0854
MDL Number:
MFCD00167482
SMILES:
CSCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)O)Cc1c[nH]c2c1cccc2)CCCNC(=N)N)Cc1ccccc1)Cc1nc[nH]c1)CCC(=O)O)N
Properties
Computed Properties
 
Complexity:
1740  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
68  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
13  
Rotatable Bond Count:
29  
XLogP3:
-2.9  

Literature

Title: Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue.

Journal: International journal of obesity (2005) 20120501

Title: Comparative study of analgesic potency of ACTH4-10 fragment and its analog semax.

Journal: Bulletin of experimental biology and medicine 20070101

Title: Overweight humans are resistant to the weight-reducing effects of melanocortin4-10.

Journal: The Journal of clinical endocrinology and metabolism 20060201

Title: Neonatal administration of ACTH4-10 and its analog Semax to young laboratory mice modulates the number of catecholaminergic neurons in adult animal diencephalon.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20040101

Title: DSLET and ACTH(4-10) increase mitotic activity of hepatocytes and suppress antibody production.

Journal: Bulletin of experimental biology and medicine 20030501

Title: Ligand-dependent activation of the melanocortin 5 receptor: cAMP production and ryanodine receptor-dependent elevations of [Ca(2+)](I).

Journal: Biochemical and biophysical research communications 20020118

Title: [Anticipated and unexpected physiological effects of oligopeptides (glyprolines, ACTH (4-10) analogs, taftsin, and thyroliberin)].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20011101

Title: Novel synthetic analogue of ACTH 4-10 (Semax) but not glycine prevents the enhanced nitric oxide generation in cerebral cortex of rats with incomplete global ischemia.

Journal: Brain research 20010309

Title: ACTH: a structure-activity study on pilocarpine-induced epilepsy.

Journal: European journal of pharmacology 19921215

Title: Entry of the synthetic ACTH(4-10) analogue into the rat brain following intravenous injection.

Journal: Neuroscience letters 19910610

Title: [Catecholaminergic component of the action of a heptapeptide analog of ACTH4-10 on the open-field behavior of rats].

Journal: Biulleten' eksperimental'noi biologii i meditsiny 19861101

Title: Antiparallel beta-sheets in the crystal structure of the heptapeptide Met-Glu-His-Phe-Arg-Trp-Gly (ACTH 4-10).

Journal: International journal of peptide and protein research 19840201

Title: Changes in muscle action potentials of patients with diseases of motor units following the infusion of a peptide fragment of ACTH.

Journal: Arzneimittel-Forschung 19770101

Title: Wellhöner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8.

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Tags:4037-01-8 Molecular Formula|4037-01-8 MDL|4037-01-8 SMILES|4037-01-8 ACTH (4-10)