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463930-25-8,MFCD10566711
Catalog No.:AA00DGQ5

463930-25-8 | BAY 55-9837

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99%
1 week  
$606.00   $424.00
- +
5mg
99%
1 week  
$1,558.00   $1,091.00
- +
10mg
99%
1 week  
$2,511.00   $1,758.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DGQ5
Chemical Name:
BAY 55-9837
CAS Number:
463930-25-8
Molecular Formula:
C167H270N52O46
Molecular Weight:
3742.2515
MDL Number:
MFCD10566711
SMILES:
NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccc(cc1)O)CCCNC(=N)N)CCCCN)CC(=O)N)CCCCN)[C@H](CC)C)CO)CCC(=O)N)CC(C)C)Cc1ccc(cc1)O)CCCCN)CCCCN)C)C)C(C)C)CCC(=O)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1nc[nH]c1)N)CO)CC(=O)O)C)Cc1ccccc1)CC(=O)O)CC(=O)N)Cc1ccc(cc1)O)CCCNC(=N)N)CC(C)C)CCCNC(=N)N
Properties
Computed Properties
 
Complexity:
8680  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
34  
Heavy Atom Count:
265  
Hydrogen Bond Acceptor Count:
56  
Hydrogen Bond Donor Count:
60  
Rotatable Bond Count:
132  
XLogP3:
-16.7  

Literature

Title: Anti-hyperglycemic, antioxidant and anti-inflammatory effects of VIP and a VPAC1 agonist on streptozotocin-induced diabetic mice.

Journal: Peptides 20110201

Title: Effects of VPAC2 receptor activation on membrane excitability and GABAergic transmission in subparaventricular zone neurons targeted by suprachiasmatic nucleus.

Journal: Journal of neurophysiology 20090901

Title: Involvement of VPAC1 and VPAC2 receptors in increasing local pancreatic blood flow in anesthetized rats.

Journal: Pancreas 20080801

Title: A novel recombinant, VPAC2-selective agonist enhancing insulin release and glucose disposal.

Journal: Acta pharmacologica Sinica 20070401

Title: Engineering novel VPAC2-selective agonists with improved stability and glucose-lowering activity in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 20070201

Title: Distribution of the VPAC2 receptor in peripheral tissues of the mouse.

Journal: Endocrinology 20040301

Title: A potent and highly selective VPAC2 agonist enhances glucose-induced insulin release and glucose disposal: a potential therapy for type 2 diabetes.

Journal: Diabetes 20020501

Title: Tsutsumi M, et, al. A potent and highly selective VPAC2 agonist enhances glucose-induced insulin release and glucose disposal: a potential therapy for type 2 diabetes. Diabetes. 2002 May; 51(5): 1453-60.

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SDS
Tags:463930-25-8 Molecular Formula|463930-25-8 MDL|463930-25-8 SMILES|463930-25-8 BAY 55-9837