Home Other Building Blocks 480449-70-5
480449-70-5,MFCD29477765
Catalog No.:AA00DA3H

480449-70-5 | Edoxaban

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$25.00   $18.00
- +
1g
98%
in stock  
$60.00   $42.00
- +
5g
98%
in stock  
$217.00   $152.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DA3H
Chemical Name:
Edoxaban
CAS Number:
480449-70-5
Molecular Formula:
C24H30ClN7O4S
Molecular Weight:
548.0575
MDL Number:
MFCD29477765
SMILES:
CN1CCc2c(C1)sc(n2)C(=O)N[C@@H]1C[C@H](CC[C@@H]1NC(=O)C(=O)Nc1ccc(cn1)Cl)C(=O)N(C)C
Properties
Computed Properties
 
Complexity:
880  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
1.4  

Downstream Synthesis Route

[1]CurrentPatentAssignee:CHONGKUNDANGPHARMACEUTICALCORP.-KR2021/30109,2021,ALocationinpatent:Paragraph0164-0280;0289-0338

[2]CurrentPatentAssignee:SKCAPITALPARTNERSLP-US2018/179226,2018,A1Locationinpatent:Paragraph0368

[3]CurrentPatentAssignee:BORYUNGPHARMCO.,LTD.;BORYUNG-WO2022/103239,2022,A1Locationinpatent:Paragraph47-48;141;151-153;154;171-172

[4]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2371830,2011,A1Locationinpatent:Page/Pagecolumn9-10

[5]CurrentPatentAssignee:CHINACHEMICALPHARMACEUTICALGROUP;CHUNGWHACHEMICALSYNTHESISBIOTECH-TWI571460,2017,BLocationinpatent:Paragraph0042-0043

[6]CurrentPatentAssignee:BEIJINGSUNNOVOPHARMACEUTICALRES-CN108484641,2018,ALocationinpatent:Paragraph0066-0069;0097-0098

[7]CurrentPatentAssignee:INNERMONGOLIAJINGDONGPHARMACEUTICAL-CN111393456,2020,ALocationinpatent:Paragraph0099-0101

[8]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-WO2021/1728,2021,A1Locationinpatent:Paragraph19-20

[9]CurrentPatentAssignee:VIATRISINC-WO2018/11823,2018,A1Locationinpatent:Page/Pagecolumn28

[10]CurrentPatentAssignee:HARBINPHARMACEUTICALGROUPCO.,LTD.-CN114736218,2022,ALocationinpatent:Paragraph0040-0044;0053-0054

[11]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP1405852,2004,A1Locationinpatent:Page424

[12]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2407450,2012,A1Locationinpatent:Page/Pagecolumn21-22

[13]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2407457,2012,A1Locationinpatent:Page/Pagecolumn17

[14]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2589590,2013,A1Locationinpatent:Paragraph0146;0147

[15]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-US2013/144061,2013,A1Locationinpatent:Paragraph0264;0265;0266;0267;0268;0269;0270

[16]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-US2015/353577,2015,A1Locationinpatent:Paragraph0099;0100

[17]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-JP5801011,2015,B2Locationinpatent:Page/Pagecolumn0214-0216

[18]CurrentPatentAssignee:SHENZHENKEXINGBIOTECH;SHANDONGKEXINGBIOPRODUCTS-CN104761571,2017,BLocationinpatent:Paragraph0063;0064;0065

[19]CurrentPatentAssignee:CorporacionQuimicoFarmaceuticaEsteveSA-WO2018/83213,2018,A1Locationinpatent:Page/Pagecolumn13

[20]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-US2017/22220,2017,A1Locationinpatent:Paragraph0050;0051;0052;0053;0054;0055;0056

[21]CurrentPatentAssignee:JIANGSUWEIKELMEDICALTECH-CN114349770,2022,ALocationinpatent:Paragraph0057-0062

[22]CurrentPatentAssignee:BORYUNGPHARMCO.,LTD.;BORYUNG-WO2022/103239,2022,A1Locationinpatent:Paragraph47-48;141;151-153-154;171-172

[23]CurrentPatentAssignee:SHANGHAIBIOSBIOTECHNOLOGY-CN115724792,2023,ALocationinpatent:Paragraph0095-0110

[24]CurrentPatentAssignee:BORYUNGPHARMCO.,LTD.;BORYUNG-WO2022/103239,2022,A1Locationinpatent:Paragraph47-48;141;151-153-154;171-172

[25]CurrentPatentAssignee:ZHEJIANGJIUZHOUPHARMCOLTD-CN116332958,2023,ALocationinpatent:Paragraph0054-0056

480452-37-7    720720-96-7   
edoxaban 

[1]CurrentPatentAssignee:INNERMONGOLIAJINGDONGPHARMACEUTICAL;BEIJINGSIHUANKEBAOPHARMACEUTICAL-CN109942600,2019,ALocationinpatent:Paragraph0239-0241

[2]CurrentPatentAssignee:INNERMONGOLIAJINGDONGPHARMACEUTICAL-CN111393456,2020,ALocationinpatent:Paragraph0091-0096

[3]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP1683800,2006,A1Locationinpatent:Page/Pagecolumn59;60

[4]CurrentPatentAssignee:CHUNGWHACHEMICALSYNTHESISBIOTECH;CHINACHEMICALPHARMACEUTICALGROUP-TWI571460,2017,BLocationinpatent:Paragraph0040-0041

720720-96-7    480452-36-6   
N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(dimethylamino)carbonyl-2-(5-methyl-4,5,6,7-tetrahydrothiazolo5,4-cpyridin-2-yl)carbonylamino}cyclohexyl)ethanediamide 

[1]CurrentPatentAssignee:BEIJINGSUNNOVOPHARMACEUTICALRES-CN108484641,2018,ALocationinpatent:Paragraph0050-0055;0089-0096

[2]CurrentPatentAssignee:MOEHSIBERICASL-WO2019/158550,2019,A1Locationinpatent:Page/Pagecolumn15-16

[3]CurrentPatentAssignee:VIATRISINC-WO2018/11823,2018,A1Locationinpatent:Page/Pagecolumn27

[4]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-WO2021/1728,2021,A1Locationinpatent:Page/Pagecolumn17-18

[5]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP1925611,2008,A1Locationinpatent:Page/Pagecolumn47-48

[6]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2407450,2012,A1Locationinpatent:Page/Pagecolumn21

[7]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2407457,2012,A1Locationinpatent:Page/Pagecolumn16

[8]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2589590,2013,A1Locationinpatent:Paragraph0144;0145

[9]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-WO2014/81047,2014,A1Locationinpatent:Page/Pagecolumn22

[10]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-US2015/353577,2015,A1Locationinpatent:Paragraph0097;0098

[11]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-JP5801011,2015,B2Locationinpatent:Page/Pagecolumn0210-0212

[12]CurrentPatentAssignee:SHANDONGKEXINGBIOPRODUCTS;SHENZHENKEXINGBIOTECH-CN104761571,2017,BLocationinpatent:Paragraph0049;0050;0051;0052;0053

[13]CurrentPatentAssignee:GAPIBIO;DONGBANGFTL;GABIBIO-JP2019/210273,2019,ALocationinpatent:Paragraph0043;0048

[14]CurrentPatentAssignee:ZHEJIANGSUPORPHARMACEUTICALSCOLTD-CN111606927,2020,ALocationinpatent:Paragraph0023-0062

[15]CurrentPatentAssignee:PHARMACOSTECHCOLTD-KR2021/152213,2021,ALocationinpatent:Paragraph0055-0057;0060;0062

[1]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2383272,2011,A1Locationinpatent:Page/Pagecolumn6-7

[2]CurrentPatentAssignee:DONG-ASTCO.,LTD.-KR2020/53270,2020,ALocationinpatent:Paragraph0221-0222

[1]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2407450,2012,A1CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2407457,2012,A1

[2]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2407457,2012,A1

[3]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2589590,2013,A1

[4]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-US2015/353577,2015,A1

[5]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-JP5801011,2015,B2

[6]CurrentPatentAssignee:SHENZHENKEXINGBIOTECH;SHANDONGKEXINGBIOPRODUCTS-CN104761571,2017,B

[7]CurrentPatentAssignee:BEIJINGSUNNOVOPHARMACEUTICALRES-CN108484641,2018,A

[8]CurrentPatentAssignee:JILINYATAI(GROUP)CO.,LTD.-CN107641131,2018,A

[9]CurrentPatentAssignee:GAPIBIO;DONGBANGFTL;GABIBIO-JP2019/210273,2019,A

[10]CurrentPatentAssignee:GAPIBIO;DONGBANGFTL;GABIBIO-JP2019/210273,2019,A

[11]CurrentPatentAssignee:GAPIBIO;DONGBANGFTL;GABIBIO-JP2019/210273,2019,A

[12]CurrentPatentAssignee:INNERMONGOLIAJINGDONGPHARMACEUTICAL-CN111393456,2020,A

[13]CurrentPatentAssignee:INNERMONGOLIAJINGDONGPHARMACEUTICAL-CN111393456,2020,A

[14]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-WO2021/1728,2021,A1

[15]CurrentPatentAssignee:BORYUNG;BORYUNGPHARMCO.,LTD.-WO2022/103239,2022,A1

[16]CurrentPatentAssignee:BORYUNG;BORYUNGPHARMCO.,LTD.-WO2022/103239,2022,A1

Literature

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Journal: Seminars in thrombosis and hemostasis 20150301

Title: The role of factor Xa inhibitors in venous thromboembolism treatment.

Journal: Vascular health and risk management 20150101

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Journal: Thrombosis and haemostasis 20121101

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SDS
Tags:480449-70-5 Molecular Formula|480449-70-5 MDL|480449-70-5 SMILES|480449-70-5 Edoxaban |Heterocyclic_Building_Blocks