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53963-43-2,MFCD06410947
Catalog No.:AA00DB5U

53963-43-2 | Ginsenoside f1

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Purity
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Price(USD)
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1mg
≥98%
in stock  
$48.00   $33.00
- +
5mg
≥98%
in stock  
$172.00   $120.00
- +
10mg
≥98%
in stock  
$229.00   $160.00
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25mg
≥98%
in stock  
$453.00   $317.00
- +
50mg
96%
in stock  
$693.00   $485.00
- +
100mg
96%
in stock  
$1,202.00   $842.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DB5U
Chemical Name:
Ginsenoside f1
CAS Number:
53963-43-2
Molecular Formula:
C36H62O9
Molecular Weight:
638.8721
MDL Number:
MFCD06410947
SMILES:
OC[C@H]1O[C@@H](O[C@]([C@H]2CC[C@@]3([C@@H]2[C@H](O)C[C@H]2[C@@]3(C)C[C@@H]([C@@H]3[C@]2(C)CC[C@@H](C3(C)C)O)O)C)(CCC=C(C)C)C)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
1110  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
16  
Heavy Atom Count:
45  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
7  
XLogP3:
4.3  

Literature

Title: Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype.

Journal: Chemico-biological interactions 20180301

Title: Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp.

Journal: Toxicology and applied pharmacology 20140301

Title: Bioconversion of major ginsenosides Rg1 to minor ginsenoside F1 using novel recombinant ginsenoside hydrolyzing glycosidase cloned from Sanguibacter keddieii and enzyme characterization.

Journal: Journal of biotechnology 20121031

Title: Co-transformation of Panax major ginsenosides Rb₁ and Rg₁ to minor ginsenosides C-K and F₁ by Cladosporium cladosporioides.

Journal: Journal of industrial microbiology & biotechnology 20120401

Title: Ginsenoside F1 production from ginsenoside Rg1 by a purified β-glucosidase from Fusarium moniliforme var. subglutinans.

Journal: Biotechnology letters 20111201

Title: Microbial transformation of ginsenoside-Rg₁ by Absidia coerulea and the reversal activity of the metabolites towards multi-drug resistant tumor cells.

Journal: Fitoterapia 20111201

Title: A novel ginsenosidase from an Aspergillus strain hydrolyzing 6-O-multi-glycosides of protopanaxatriol-type ginsenosides, named ginsenosidase type IV.

Journal: Journal of microbiology and biotechnology 20111001

Title: Purification and characterization of a novel and unique ginsenoside Rg1-hydrolyzing β-D-glucosidase from Penicillium sclerotiorum.

Journal: Acta biochimica et biophysica Sinica 20110301

Title: [Pharmacokinetics of ginsenosides Rg1 and its metabolites in rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100501

Title: Dammarane-type saponins from the flower buds of Panax ginseng and their effects on human leukemia cells.

Journal: Bioorganic & medicinal chemistry letters 20100101

Title: Influence of ginsenoside Rh1 and F1 on human cytochrome p450 enzymes.

Journal: Planta medica 20060201

Title: Ginsenoside F1 protects human HaCaT keratinocytes from ultraviolet-B-induced apoptosis by maintaining constant levels of Bcl-2.

Journal: The Journal of investigative dermatology 20030901

Title: Degradation of ginsenosides in humans after oral administration.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030801

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1.

Journal: Chemical & pharmaceutical bulletin 20030401

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1 from protopanaxatriol-type ginseng saponin mixture.

Journal: Planta medica 20030301

Title: [Saponins with low sugar chain from the leaves of Panax notoginseng (Burk) F. H. Chen].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020301

Title: Wang DD, et al. Rare ginsenoside Ia synthesized from F1 by cloning and overexpression of the UDP-glycosyltransferase gene from Bacillus subtilis: synthesis, characterization, and in vitromelanogenesis inhibition activity in BL6B16 cells. J Ginseng Res. 2018 Jan;42(1):42-49.

Title: Qin M, et al. Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling. Front Pharmacol. 2017 Dec 22;8:953.

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