Title: Influence of adult age on the total and free clearance and protein binding of (R)- and (S)-warfarin.
Journal: British journal of clinical pharmacology 20121101
Title: Vorapaxar, an oral PAR-1 receptor antagonist, does not affect the pharmacokinetics and pharmacodynamics of warfarin.
Journal: European journal of clinical pharmacology 20121101
Title: Enantioselective synthesis of coumarin derivatives by PYBOX-DIPH-Zn(II) complex catalyzed Michael reaction.
Journal: The Journal of organic chemistry 20121005
Title: Effect of carisbamate on the pharmacokinetics and pharmacodynamics of warfarin in healthy participants.
Journal: Journal of clinical pharmacology 20120901
Title: CYP4F2 gene polymorphism as a contributor to warfarin maintenance dose in Japanese subjects.
Journal: Journal of clinical pharmacy and therapeutics 20120801
Title: The effect of fimasartan, an angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy Korean male volunteers: a one-sequence, two-period crossover clinical trial.
Journal: Clinical therapeutics 20120701
Title: Effects of CYP4F2 gene polymorphisms on warfarin clearance and sensitivity in Korean patients with mechanical cardiac valves.
Journal: Therapeutic drug monitoring 20120601
Title: Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model.
Journal: Archives of toxicology 20120301
Title: Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120115
Title: The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors.
Journal: British journal of clinical pharmacology 20120101
Title: [Enantioselective determinination of R-warfarin/S-warfarin in human plasma using liquid chromatography-tandem mass spectrometry and its application in a drug-drug interaction study].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120101
Title: Stereoselective regulations of P-glycoprotein by ginsenoside Rh2 epimers and the potential mechanisms from the view of pharmacokinetics.
Journal: PloS one 20120101
Title: Drug interaction of (S)-warfarin, and not (R)-warfarin, with itraconazole in a hematopoietic stem cell transplant recipient.
Journal: Clinica chimica acta; international journal of clinical chemistry 20111009
Title: Drug-drug interaction study to assess the effects of multiple-dose pitavastatin on steady-state warfarin in healthy adult volunteers.
Journal: Journal of clinical pharmacology 20110901
Title: Effects of fesoterodine on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers.
Journal: British journal of clinical pharmacology 20110801
Title: Lack of pharmacokinetic and pharmacodynamic interactions of roflumilast with (R, S)-warfarin in healthy adult subjects.
Journal: International journal of clinical pharmacology and therapeutics 20110601
Title: Novel multi-mode ultra performance liquid chromatography-tandem mass spectrometry assay for profiling enantiomeric hydroxywarfarins and warfarin in human plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110501
Title: Probable interaction between warfarin and rifaximin in a patient treated for small intestine bacterial overgrowth.
Journal: The Annals of pharmacotherapy 20110501
Title: Effect of linagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers.
Journal: International journal of clinical pharmacology and therapeutics 20110501
Title: Simultaneous determination of warfarin and 7-hydroxywarfarin enantiomers by high-performance liquid chromatography with ultraviolet detection.
Journal: Therapeutic drug monitoring 20110201
Title: Genetics of warfarin sensitivity in an emergency department population with thromboembolic.
Journal: The western journal of emergency medicine 20110201
Title: Effects of nilotinib on single-dose warfarin pharmacokinetics and pharmacodynamics: a randomized, single-blind, two-period crossover study in healthy subjects.
Journal: Clinical drug investigation 20110101
Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.
Journal: Clinical Medicine Insights. Cardiology 20110101
Title: Gene-drug interaction in stroke.
Journal: Stroke research and treatment 20110101
Title: Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.
Journal: Drug metabolism letters 20101201
Title: Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes.
Journal: Journal of thrombosis and haemostasis : JTH 20101201
Title: Warfarin toxicity and individual variability-clinical case.
Journal: Toxins 20101101
Title: Effect of single-dose rifampin on the pharmacokinetics of warfarin in healthy volunteers.
Journal: Clinical pharmacology and therapeutics 20101001
Title: Standard warfarin dose in a patient with the CYP2C9*3/*3 genotype leads to hematuria.
Journal: Clinica chimica acta; international journal of clinical chemistry 20100906
Title: Interaction between warfarin and the herbal product Shengmai-yin: a case report of intracerebral hematoma.
Journal: Yonsei medical journal 20100901
Title: Simultaneous measurement of S-warfarin, R-warfarin, S-7-hydroxywarfarin and R-7-hydroxywarfarin in human plasma by liquid chromatography-tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20100605
Title: Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.
Journal: Chemical research in toxicology 20100517
Title: Effect of casopitant, a novel NK-1 receptor antagonist, on the pharmacokinetics and pharmacodynamics of steady-state warfarin.
Journal: Journal of clinical pharmacology 20100501
Title: Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism.
Journal: Drug metabolism reviews 20100201
Title: Effects of folic acid supplementation on the pharmacokinetics and anticoagulant effect of warfarin: an open-label, prospective study of long-term administration in adults.
Journal: Clinical therapeutics 20100201
Title: Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.
Journal: British journal of clinical pharmacology 20100201
Title: Effect of eslicarbazepine acetate on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy subjects during a three-stage, open-label, multiple-dose, single-period study.
Journal: Clinical therapeutics 20100101
Title: Adverse Interaction between Capecitabine and Warfarin Resulting in Altered Coagulation Parameters: A Review of the Literature Starting from a Case Report.
Journal: Case reports in medicine 20100101
Title: Update on treatment of partial onset epilepsy: role of eslicarbazepine.
Journal: Neuropsychiatric disease and treatment 20100101
Title: VKORC1 pharmacogenetics and pharmacoproteomics in patients on warfarin anticoagulant therapy: transthyretin precursor as a potential biomarker.
Journal: PloS one 20100101
Title: Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective.
Journal: Drug design, development and therapy 20100101
Title: Interaction between clopidogrel and proton-pump inhibitors and management strategies in patients with cardiovascular diseases.
Journal: Drug, healthcare and patient safety 20100101
Title: New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
Title: Evaluation of silica monoliths in affinity microcolumns for high-throughput analysis of drug-protein interactions.
Journal: Journal of separation science 20090801
Title: The absence of an interaction between warfarin and cranberry juice: a randomized, double-blind trial.
Journal: Journal of clinical pharmacology 20090701
Title: The pharmacokinetics and pharmacodynamics of warfarin in combination with ambrisentan in healthy volunteers.
Journal: British journal of clinical pharmacology 20090501
Title: Effect of rutin on warfarin anticoagulation and pharmacokinetics of warfarin enantiomers in rats.
Journal: The Journal of pharmacy and pharmacology 20090401
Title: A review of exenatide as adjunctive therapy in patients with type 2 diabetes.
Journal: Drug design, development and therapy 20090101
Title: Preparation and characterization of poly(l-phenylalanine) chiral stationary phases with varying peptide length.
Journal: Journal of chromatography. A 20081024
Title: Effect of nebicapone on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Journal: European journal of clinical pharmacology 20081001
Title: Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4.
Journal: Cancer chemotherapy and pharmacology 20080901
Title: Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects.
Journal: British journal of pharmacology 20080801
Title: The role of cytochrome P2C19 in R-warfarin pharmacokinetics and its interaction with omeprazole.
Journal: Therapeutic drug monitoring 20080601
Title: Development of an affinity silica monolith containing human serum albumin for chiral separations.
Journal: Journal of pharmaceutical and biomedical analysis 20080414
Title: The effect of CYP2C19 genotypes on the pharmacokinetics of warfarin enantiomers.
Journal: Journal of clinical pharmacy and therapeutics 20080201
Title: Ciprofloxacin prolonged-release tablets do not affect warfarin pharmacokinetics and pharmacodynamics.
Journal: Journal of clinical pharmacology 20071001
Title: The effect of 1-furan-2-yl-3-pyridine-2-yl-propenone on pharmacokinetic parameters of warfarin.
Journal: Archives of pharmacal research 20070701
Title: Effects of daily ingestion of cranberry juice on the pharmacokinetics of warfarin, tizanidine, and midazolam--probes of CYP2C9, CYP1A2, and CYP3A4.
Journal: Clinical pharmacology and therapeutics 20070601
Title: Simultaneous determination of warfarin enantiomers and its metabolite in human plasma by column-switching high-performance liquid chromatography with chiral separation.
Journal: Therapeutic drug monitoring 20070601
Title: Development of an affinity silica monolith containing alpha1-acid glycoprotein for chiral separations.
Journal: Journal of chromatography. A 20070518
Title: A PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy.
Journal: Clinical pharmacology and therapeutics 20070401
Title: Plasma S/R ratio of warfarin co-varies with VKORC1 haplotype.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070401
Title: Association of warfarin dose with genes involved in its action and metabolism.
Journal: Human genetics 20070301
Title: Warfarin metabolism and anticoagulant effect: a prospective, observational study of the impact of CYP2C9 genetic polymorphism in the presence of drug-disease and drug-drug interactions.
Journal: Clinical therapeutics 20070301
Title: Supercritical fluid chromatography-tandem mass spectrometry for fast bioanalysis of R/S-warfarin in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis 20061116
Title: Main haplotypes and mutational analysis of vitamin K epoxide reductase (VKORC1) in a Swedish population: a retrospective analysis of case records.
Journal: Journal of thrombosis and haemostasis : JTH 20060801
Title: VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients.
Journal: Clinical pharmacology and therapeutics 20060801
Title: The influence of co-treatment with carbamazepine, amiodarone and statins on warfarin metabolism and maintenance dose.
Journal: European journal of clinical pharmacology 20060401
Title: A new high-performance liquid chromatographic method for determination of warfarin enantiomers.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105
Title: The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen.
Journal: Blood 20051001
Title: Effect of omeprazole on the hydroxylation of warfarin enantiomers in human: in-vitro studies with liver microsomes and cDNA-expressed cytochrome P450 isozymes.
Journal: Current drug metabolism 20051001
Title: Kinetic study of cytochrome P450 3A4 activity on warfarin by capillary electrophoresis with fluorescence detection.
Journal: Journal of chromatography. A 20050805
Title: Significant effect of capecitabine on the pharmacokinetics and pharmacodynamics of warfarin in patients with cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050720
Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.
Journal: Chemical research in toxicology 20050601
Title: Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20050401
Title: Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20050401
Title: Effect of coenzyme Q10 on warfarin hydroxylation in rat and human liver microsomes.
Journal: Current drug metabolism 20050401
Title: High-performance affinity monolith chromatography: development and evaluation of human serum albumin columns.
Journal: Analytical chemistry 20041201
Title: Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection.
Journal: The Journal of pharmacology and experimental therapeutics 20041001
Title: Development and evaluation of N-hydroxysuccinimide-activated silica for immobilizing human serum albumin in liquid chromatography columns.
Journal: Journal of chromatography. A 20040917
Title: Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20040501
Title: Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501
Title: Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin.
Journal: Clinical pharmacology and therapeutics 20040301
Title: Combination of chiral capillary electrochromatography with electrospray ionization mass spectrometry: method development and assay of warfarin enantiomers in human plasma.
Journal: Analytical chemistry 20031115
Title: Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101
Title: Kiiv, an in vivo parameter for predicting the magnitude of a drug interaction arising from competitive enzyme inhibition.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20030801
Title: High-performance liquid-chromatographic determination of warfarin enantiomers in plasma with automated on-line sample enrichment.
Journal: Journal of biochemical and biophysical methods 20021231
Title: Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance.
Journal: Clinical pharmacology and therapeutics 20021201
Title: Warfarin dose adjustments based on CYP2C9 genetic polymorphisms.
Journal: Journal of thrombosis and thrombolysis 20021201
Title: Stereoselective kinetics of warfarin binding to human serum albumin: effect of an allosteric interaction.
Journal: Chirality 20020515
Title: Effect of the catechol-O-methyltransferase inhibitor entacapone on the steady-state pharmacokinetics and pharmacodynamics of warfarin.
Journal: British journal of clinical pharmacology 20020501
Title: Effect of modafinil at steady state on the single-dose pharmacokinetic profile of warfarin in healthy volunteers.
Journal: Journal of clinical pharmacology 20020201
Title: Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarin.
Journal: Epilepsy research 20011101
Title: Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe.
Journal: Journal of clinical pharmacology 20010701
Title: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.
Journal: The Journal of biological chemistry 20010622
Title: In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601
Title: The effect of anastrozole on the single-dose pharmacokinetics and anticoagulant activity of warfarin in healthy volunteers.
Journal: British journal of clinical pharmacology 20010501
Title: The stereoselective effects of bucolome on the pharmacokinetics and pharmacodynamics of racemic warfarin.
Journal: Journal of clinical pharmacology 20010401
Title: Effect of ubidecarenone on warfarin anticoagulation and pharmacokinetics of warfarin enantiomers in rats.
Journal: Drug metabolism and drug interactions 20010101
Title: Drug interaction studies with esomeprazole, the (S)-isomer of omeprazole.
Journal: Clinical pharmacokinetics 20010101
