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60482-95-3,MFCD00076686
Catalog No.:AA01EA2E

60482-95-3 | NEurotensin(8-13)

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1mg
98%
in stock  
$17.00   $12.00
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5mg
98%
in stock  
$41.00   $29.00
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10mg
98%
in stock  
$60.00   $42.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EA2E
Chemical Name:
NEurotensin(8-13)
CAS Number:
60482-95-3
Molecular Formula:
C38H64N12O8
Molecular Weight:
816.9904
MDL Number:
MFCD00076686
SMILES:
CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)O)CC(C)C)NC(=O)[C@H](Cc1ccc(cc1)O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)N)CCCNC(=N)N)C
Properties
Computed Properties
 
Complexity:
1430  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
58  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
11  
Rotatable Bond Count:
24  
Undefined Atom Stereocenter Count:
7  
XLogP3:
-4  

Literature

Title: Solid-phase extraction-field-amplified sample injection coupled with CE-ESI-MS for online pre-concentration and quantitative analysis of brain-gut peptides.

Journal: Electrophoresis 20111001

Title: Target-selective drug delivery through liposomes labeled with oligobranched neurotensin peptides.

Journal: ChemMedChem 20110404

Title: Neurotensin(8-13) analogue: radiolabeling and biological evaluation using different chelators.

Journal: Nuclear medicine and biology 20110101

Title: Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.

Journal: Journal of medicinal chemistry 20100624

Title: Synthesis of neurotensin(8-13)-phosphopeptide heterodimers via click chemistry.

Journal: Bioorganic & medicinal chemistry letters 20100601

Title: Comparison of N-terminal modifications on neurotensin(8-13) analogues correlates peptide stability but not binding affinity with in vivo efficacy.

Journal: Journal of medicinal chemistry 20090409

Title: Separation and determination of peptide hormones by capillary electrophoresis with laser-induced fluorescence coupled with transient pseudo-isotachophoresis preconcentration.

Journal: Analytical biochemistry 20080915

Title: Neurotensin in the ventral pallidum increases extracellular gamma-aminobutyric acid and differentially affects cue- and cocaine-primed reinstatement.

Journal: The Journal of pharmacology and experimental therapeutics 20080501

Title: Radiolabeling of multimeric neurotensin(8-13) analogs with the short-lived positron emitter fluorine-18.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20070701

Title: Synthesis and evaluation of novel multimeric neurotensin(8-13) analogs.

Journal: Bioorganic & medicinal chemistry 20060901

Title: Radionuclide imaging of small-cell lung cancer (SCLC) using 99mTc-labeled neurotensin peptide 8-13.

Journal: Nuclear medicine and biology 20060501

Title: Novel 99mTc-labeled neurotensin analogues with optimized biodistribution properties.

Journal: Journal of medicinal chemistry 20060309

Title: Design, synthesis, and evaluation of the antipsychotic potential of orally bioavailable neurotensin (8-13) analogues containing non-natural arginine and lysine residues.

Journal: Neuropharmacology 20051201

Title: In vivo behavioral effects of stable, receptor-selective neurotensin[8-13] analogues that cross the blood-brain barrier.

Journal: Neuropharmacology 20050301

Title: Gq/11-induced and spontaneous waves of coordinated network activation in developing frontal cortex.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216

Title: In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues.

Journal: Journal of medicinal chemistry 20030911

Title: Prolyl endopeptidase inhibitory peptides in wine.

Journal: Bioscience, biotechnology, and biochemistry 20030201

Title: Synthesis and biological studies of novel neurotensin(8-13) mimetics.

Journal: Bioorganic & medicinal chemistry 20021201

Title: The neurotensin fragment AcNT(8-13) inhibits lowering of interstitial fluid pressure in rat trachea.

Journal: American journal of physiology. Heart and circulatory physiology 20020901

Title: Monitoring neurotensin[8-13] degradation in human and rat serum utilizing matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Analytical biochemistry 20020901

Title: Probing the environment of neurotensin whilst bound to the neurotensin receptor by solid state NMR.

Journal: FEBS letters 20020508

Title: Influence of silaproline on peptide conformation and bioactivity.

Journal: Journal of the American Chemical Society 20020327

Title: Preclinical evaluation of a new, stabilized neurotensin(8--13) pseudopeptide radiolabeled with (99m)tc.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020301

Title: Topography of the neurotensin (NT)(8-9) binding site of human NT receptor-1 probed with NT(8-13) analogs.

Journal: The journal of peptide research : official journal of the American Peptide Society 20020201

Title: Biodistribution and catabolism of (18)F-labeled neurotensin(8-13) analogs.

Journal: Nuclear medicine and biology 20020101

Title: Presynaptic action of neurotensin on cultured ventral tegmental area dopaminergic neurones.

Journal: Neuroscience 20020101

Title: In vitro and in vivo evaluation of new radiolabeled neurotensin(8-13) analogues with high affinity for NT1 receptors.

Journal: Nuclear medicine and biology 20010101

Title: Neurotensin modulates the electrical activity of frog pituitary melanotropes via activation of a G-protein-coupled receptor pharmacologically related to both the NTS1 and nts2 receptors of mammals.

Journal: Neuroendocrinology 20001201

Title: A single amino acid of the human and rat neurotensin receptors (subtype 1) determining the pharmacological profile of a species-selective neurotensin agonist.

Journal: Biochemical pharmacology 20000915

Title: Coloured peptides: synthesis, properties and use in preparation of peptide sub-library kits.

Journal: Journal of peptide science : an official publication of the European Peptide Society 19980601

Title: García-Garayoa E, et al. Preclinical evaluation of a new, stabilized neurotensin(8--13) pseudopeptide radiolabeled with (99m)tc. J Nucl Med. 2002 Mar;43(3):374-83.

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Tags:60482-95-3 Molecular Formula|60482-95-3 MDL|60482-95-3 SMILES|60482-95-3 NEurotensin(8-13)