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6051-87-2,MFCD00004986
Catalog No.:AA00E9CG

6051-87-2 | 3-phenyl-1H-benzo[f]chromen-1-one

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250mg
99%
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$26.00   $18.00
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1g
≥98%
in stock  
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5g
≥98%
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$166.00   $116.00
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10g
≥98%
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$306.00   $214.00
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25g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00E9CG
Chemical Name:
3-phenyl-1H-benzo[f]chromen-1-one
CAS Number:
6051-87-2
Molecular Formula:
C19H12O2
Molecular Weight:
272.2974
MDL Number:
MFCD00004986
SMILES:
O=c1cc(oc2c1c1ccccc1cc2)c1ccccc1
NSC Number:
136015
Properties
Computed Properties
 
Complexity:
433  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
4.4  

Downstream Synthesis Route

[1]Hishidaetal.[NipponKagakuZasshi,1953,vol.74,p.697][Chem.Abstr.,1954,p.12094]

[2]Mahaletal.[JournaloftheChemicalSociety,1935,p.866]

[1]Garg,S.;Ishar,M.P.S.;Sarin,R.;Gandhi,R.P.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1994,vol.33,#12,p.1123-1128]

[2]Singh,JatinderV.;Kaur,Anumeet;Bhagat,Kavita;Gupta,ManishK.;Singh,Manwinder;Singh,Harbinder;Bedi,PreetMohinderS.[MedChemComm,2018,vol.9,#3,p.490-502]Singh,JatinderV.;Mal,Gurbachan;Kaur,Gurleen;Gupta,ManishK.;Singh,Amritpal;Nepali,Kunal;Singh,Harbinder;Sharma,Sahil;Bedi,S.PreetMohinder[MedChemComm,2019,vol.10,#1,p.128-147]

[3]Ullal;Shah;Wheeler[JournaloftheChemicalSociety,1940,p.1499]Bhalla;Mahal;Venkataraman[JournaloftheChemicalSociety,1935,p.868]

[4]Springsteel,MarkF.;Galietta,LuisJ.V.;Ma,Tonghui;By,Kolbot;Berger,GideonO.;Yang,Hong;Dicus,ChristopherW.;Choung,Wonken;Quan,Chao;Shelat,AnangA.;Guy,R.Kiplin;Verkman;Kurth,MarkJ.;Nantz,MichaelH.[BioorganicandMedicinalChemistry,2003,vol.11,#18,p.4113-4120]

β-2naphthyloxy-cinnamicacid 
  6051-87-2 

[1]Ruhemann[ChemischeBerichte,1914,vol.47,p.120]

[1]Schoenberg[ChemischeBerichte,1925,vol.58,p.1801]

[2]Desaietal.[JournaloftheMaharajaSayajiraoUniversityofBaroda,1955,vol.4,#2,p.1,5]

[3]Pillon;Massicot[BulletindelaSocieteChimiquedeFrance,1954,p.26,29]

[1]Menon;Venkataraman[JournaloftheChemicalSociety,1931,p.2591,2596]

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Journal: Digestive diseases and sciences 20110901

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Journal: Toxicology letters 20110510

Title: The influence of water temperature on induced liver EROD activity in Atlantic cod (Gadus morhua) exposed to crude oil and oil dispersants.

Journal: Ecotoxicology and environmental safety 20110501

Title: Aryl hydrocarbon receptor ligands of widely different toxic equivalency factors induce similar histone marks in target gene chromatin.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110501

Title: Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by β-naphthoflavone involving TNFα-signaling due to oxidative cellular stress in rats.

Journal: Toxicology 20110428

Title: Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.

Journal: Toxicology and applied pharmacology 20110401

Title: Evaluation of the reproductive and developmental risks of caffeine.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20110401

Title: Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone.

Journal: Molecular pharmacology 20110301

Title: Hepatic coenzyme Q redox balance of fishes as a potential bioindicator of environmental contamination by polycyclic aromatic hydrocarbons.

Journal: Biology letters 20110223

Title: Cellular glutathione content modulates the effect of andrographolide on β-naphthoflavone-induced CYP1A1 mRNA expression in mouse hepatocytes.

Journal: Toxicology 20110204

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Journal: Molecular human reproduction 20110201

Title: Environmental contaminant effects on juvenile striped bass in the San Francisco Estuary, California, USA.

Journal: Environmental toxicology and chemistry 20110201

Title: New CYP1 genes in the frog Xenopus (Silurana) tropicalis: induction patterns and effects of AHR agonists during development.

Journal: Toxicology and applied pharmacology 20110115

Title: Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes.

Journal: Drug metabolism letters 20110101

Title: Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder.

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Title: Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens.

Journal: Neuro endocrinology letters 20110101

Title: Neonatal androgenization exacerbates alcohol-induced liver injury in adult rats, an effect abrogated by estrogen.

Journal: PloS one 20110101

Title: Increased glutathione synthesis following Nrf2 activation by vanadyl sulfate in human chang liver cells.

Journal: International journal of molecular sciences 20110101

Title: Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.

Journal: Chemical research in toxicology 20101220

Title: A multi-endpoint evaluation of cytochrome P450 1A2, 2B6 and 3A4 induction response in human hepatocyte cultures after treatment with β-naphthoflavone, phenobarbital and rifampicin.

Journal: Drug metabolism letters 20101201

Title: A mechanism-based mathematical model of aryl hydrocarbon receptor-mediated CYP1A induction in rats using beta-naphthoflavone as a tool compound.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Benzo[a]pyrene inhibits angiogenic factors-induced alphavbeta3 integrin expression, neovasculogenesis, and angiogenesis in human umbilical vein endothelial cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201

Title: One-way inhibiting cross-talk between arylhydrocarbon receptor (AhR) and estrogen receptor (ER) signaling in primary cultures of rainbow trout hepatocytes.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20101101

Title: Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays.

Journal: European journal of medicinal chemistry 20101101

Title: Comparative chronic liver toxicity of benzo[a]pyrene in two populations of the atlantic killifish (Fundulus heteroclitus) with different exposure histories.

Journal: Environmental health perspectives 20101001

Title: CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101001

Title: Spatio-temporal development of CYP1 activity in early life-stages of zebrafish (Danio rerio).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20101001

Title: Effects of fish CYP inducers on difloxacin N-demethylation in kidney cell of Chinese idle (Ctenopharyngodon idellus).

Journal: Fish physiology and biochemistry 20100901

Title: Liverbeads: a practical and relevant in vitro model for gene induction investigations.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901

Title: Malformation of certain brain blood vessels caused by TCDD activation of Ahr2/Arnt1 signaling in developing zebrafish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100815

Title: Flavin-containing monooxygenase-3: induction by 3-methylcholanthrene and complex regulation by xenobiotic chemicals in hepatoma cells and mouse liver.

Journal: Toxicology and applied pharmacology 20100815

Title: AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic killifish (Fundulus heteroclitus).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100815

Title: Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: synthesis, evaluation and SAR.

Journal: European journal of medicinal chemistry 20100701

Title: The role of small-intestinal P450 enzymes in protection against systemic exposure of orally administered benzo[a]pyrene.

Journal: The Journal of pharmacology and experimental therapeutics 20100701

Title: The effect of beta-naphthoflavone on the metabolism of amiodarone by hepatic and extra-hepatic microsomes.

Journal: Toxicology letters 20100602

Title: 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis is not enhanced by CYP1A inducers, alpha- and beta-naphthoflavone: relationship to intralobular distribution of CYP1A expression.

Journal: Toxicologic pathology 20100601

Title: Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16alpha-carbonitrile, rifampicin, and beta-naphthoflavone.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100510

Title: Induction of hepatic carbonyl reductase/20beta-hydroxysteroid dehydrogenase mRNA in rainbow trout downstream from sewage treatment works--possible roles of aryl hydrocarbon receptor agonists and oxidative stress.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100505

Title: Toxicological application of primary hepatocyte cell cultures of Atlantic cod (Gadus morhua)--effects of BNF, PCDD and Cd.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100501

Title: Disruption of CLOCK-BMAL1 transcriptional activity is responsible for aryl hydrocarbon receptor-mediated regulation of Period1 gene.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100501

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401

Title: Neurogenic-committed human pre-adipocytes express CYP1A isoforms.

Journal: Chemico-biological interactions 20100330

Title: Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies.

Journal: Analytical and bioanalytical chemistry 20100301

Title: Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR.

Journal: Nutrients 20100301

Title: Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone.

Journal: Toxicology 20100209

Title: Follow-up to the pre-validation of a harmonised protocol for assessment of CYP induction responses in freshly isolated and cryopreserved human hepatocytes with respect to culture format, treatment, positive reference inducers and incubation conditions.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201

Title: Inter-laboratory evaluation of the response of primary human hepatocyte cultures to model CYP inducers - a European Centre for Validation of Alternative Methods (ECVAM) - funded pre-validation study.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201

Title: Identification of AhR-regulated genes involved in PAH-induced immunotoxicity using a highly-sensitive DNA chip, 3D-Gene Human Immunity and Metabolic Syndrome 9k.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100201

Title: beta-Naphthoflavone analogs as potent and soluble aryl hydrocarbon receptor agonists: improvement of solubility by disruption of molecular planarity.

Journal: Bioorganic & medicinal chemistry 20100201

Title: CYP1A inhibition in fish gill filaments: a novel assay applied on pharmaceuticals and other chemicals.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20100131

Title: The effect of CYP1A induction on amiodarone disposition in the rat.

Journal: Journal of pharmaceutical sciences 20100101

Title: Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators.

Journal: Molecular endocrinology (Baltimore, Md.) 20100101

Title: Chemoprevention of cigarette smoke-induced alterations of MicroRNA expression in rat lungs.

Journal: Cancer prevention research (Philadelphia, Pa.) 20100101

Title: Development of a UGT1A1 reporter gene assay for induction studies: correlation between reporter gene data and regulation of UGT1A1 in human hepatocytes.

Journal: Drug metabolism letters 20100101

Title: A common carcinogen benzo[a]pyrene causes neuronal death in mouse via microglial activation.

Journal: PloS one 20100101

Title: Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells.

Journal: BMC biochemistry 20100101

Title: Polycyclic aromatic hydrocarbon components contribute to the mitochondria-antiapoptotic effect of fine particulate matter on human bronchial epithelial cells via the aryl hydrocarbon receptor.

Journal: Particle and fibre toxicology 20100101

Title: Potent modification of inducible CYP1A1 expression by flavonoids.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Dioxin toxicity in vivo results from an increase in the dioxin-independent transcriptional activity of the aryl hydrocarbon receptor.

Journal: PloS one 20100101

Title: Aromatic hydrocarbons upregulate glyceraldehyde-3-phosphate dehydrogenase and induce changes in actin cytoskeleton. Role of the aryl hydrocarbon receptor (AhR).

Journal: Toxicology 20091221

Title: Synergistic increases of metabolism and oxidation-reduction genes on their expression after combined treatment with a CYP1A inducer and andrographolide.

Journal: Chemico-biological interactions 20091210

Title: Modulation of ascorbic acid metabolism by cytochrome P450 induction revealed by metabonomics and transcriptional profiling.

Journal: Magnetic resonance in chemistry : MRC 20091201

Title: Effect of beta-naphthoflavone on AhR-regulated genes (CYP1A1, 1A2, 1B1, 2S1, Nrf2, and GST) and antioxidant enzymes in various brain regions of pig.

Journal: Toxicology 20091130

Title: Induced expression of drug metabolizing enzymes by preventive agents: role of the antioxidant response element.

Journal: Chemico-biological interactions 20091110

Title: Beta-naphthoflavone causes an AhR-independent inhibition of invasion and intracellular multiplication of Listeria monocytogenes in murine hepatocytes.

Journal: Microbial pathogenesis 20091101

Title: beta-Naphthoflavone protects mice from aristolochic acid-I-induced acute kidney injury in a CYP1A dependent mechanism.

Journal: Acta pharmacologica Sinica 20091101

Title: Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.

Journal: International journal of experimental pathology 20091001

Title: Characterization of new metabolites from in vivo biotransformation of 2-amino-3-methylimidazo[4,5-f]quinoline in mouse by mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20090901

Title: Reduction of vitellogenin synthesis by an aryl hydrocarbon receptor agonist in the white sturgeon (Acipenser transmontamus).

Journal: Environmental toxicology and chemistry 20090801

Title: Identification of new 2-amino-3-methylimidazo[4,5-f]quinoline urinary metabolites from beta-naphthoflavone-treated mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090801

Title: Lack of constitutive and inducible ethoxyresorufin-O-deethylase activity in the liver of suckermouth armored catfish (Hypostomus affinis and Hypostomus auroguttatus, Loricariidae).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090801

Title: Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study.

Journal: Chemical research in toxicology 20090701

Title: Inhibitive effect of diphenytriazol on rat cytochrome P450 enzyme in vitro.

Journal: Die Pharmazie 20090701

Title: Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes.

Journal: Toxicology letters 20090622

Title: Expression and inducibility of CYP1A1, 1A2, 1B1 by beta-naphthoflavone and CYP2B22, 3A22, 3A29, 3A46 by rifampicin in the respiratory and olfactory mucosa of pig.

Journal: Toxicology 20090616

Title: Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090601

Title: Mono-hydroxylated polychlorinated biphenyls are potent aryl hydrocarbon receptor ligands in recombinant yeast cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090601

Title: Molecular expression analysis of beta-naphthoflavone-induced hepatocellular tumors in rats.

Journal: Toxicologic pathology 20090601

Title: Estrogen receptor subtype- and promoter-specific modulation of aryl hydrocarbon receptor-dependent transcription.

Journal: Molecular cancer research : MCR 20090601

Title: Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo administration to rats and in vitro in rat and human hepatocyte cultures.

Journal: Chemico-biological interactions 20090515

Title: Effects of naphthalene, beta-naphthoflavone and benzo(a)pyrene on the diurnal and nocturnal indoleamine metabolism and melatonin content in the pineal organ of rainbow trout, Oncorhynchus mykiss.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20090402

Title: Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090401

Title: Tamoxifen as an emerging endocrine disruptor. effects on fish reproduction and detoxification target genes.

Journal: Annals of the New York Academy of Sciences 20090401

Title: Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation.

Journal: Oncogene 20090319

Title: Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle.

Journal: Molecular pharmacology 20090301

Title: Functionalized 3-benzylidene-indolin-2-ones: inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity.

Journal: Bioorganic & medicinal chemistry 20090301

Title: Involvement of the CYP1A subfamily in stereoselective metabolism of carvedilol in beta-naphthoflavone-treated Caco-2 cells.

Journal: Biological & pharmaceutical bulletin 20090301

Title: Use of mRNA expression to detect the induction of drug metabolising enzymes in rat and human hepatocytes.

Journal: Toxicology and applied pharmacology 20090215

Title: Recombinant aryl hydrocarbon receptors for bioassay of aryl hydrocarbon receptor ligands in transgenic tobacco plants.

Journal: Plant biotechnology journal 20090201

Title: Aryl hydrocarbon receptor-mediated apoptosis of neuronal cells: a possible interaction with estrogen receptor signaling.

Journal: Neuroscience 20090123

Title: The zebrafish gill model: induction of CYP1A, EROD and PAH adduct formation.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20090118

Title: beta-Naphthoflavone and benzo(a)pyrene alter dopaminergic, noradrenergic, and serotonergic systems in brain and pituitary of rainbow trout (Oncorhynchus mykiss).

Journal: Ecotoxicology and environmental safety 20090101

Title: Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine.

Journal: PloS one 20090101

Title: Intestinal cellular localization of PCNA protein and CYP1A mRNA in Atlantic salmon Salmo salar L. exposed to a model toxicant.

Journal: BMC physiology 20090101

Title: Revealing genes associated with vitellogenesis in the liver of the zebrafish (Danio rerio) by transcriptome profiling.

Journal: BMC genomics 20090101

Title: Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes.

Journal: PloS one 20090101

Title: Coal dust alters beta-naphthoflavone-induced aryl hydrocarbon receptor nuclear translocation in alveolar type II cells.

Journal: Particle and fibre toxicology 20090101

Title: Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response.

Journal: PloS one 20090101

Title: Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Journal: Genome medicine 20090101

Title: Evaluation of induction potency of new drug candidates on CYP1A2 and CYP3A4 using real-time one-step RT-PCR in primary cultures of cryopreserved human hepatocytes.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.

Journal: PloS one 20090101

Title: Modulation of cytochrome P450 enzyme system by selected flavonoids.

Journal: Neuro endocrinology letters 20090101

Title: EROD and MROD as Markers of Cytochrome P450 1A Activities in Hepatic Microsomes from Entire and Castrated Male Pigs.

Journal: Sensors (Basel, Switzerland) 20090101

Title: Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.

Journal: Archives of toxicology 20081201

Title: Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.

Journal: Archives of toxicology 20081201

Title: Induction of hepatic glutathione S-transferases in male mice by prototypes of various classes of microsomal enzyme inducers.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081201

Title: Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury.

Journal: Toxicology and applied pharmacology 20081201

Title: In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron.

Journal: Chemosphere 20081201

Title: Transcriptome profiling in crustaceans as a tool for ecotoxicogenomics: Daphnia magna DNA microarray.

Journal: Cell biology and toxicology 20081201

Title: Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20081201

Title: Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation.

Journal: Nature genetics 20081201

Title: Energy intake affects the biotransformation rate, scope for induction, and metabolite profile of benzo[a]pyrene in rainbow trout.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20081121

Title: Modulatory role of copper on β-naphthoflavone-induced DNA damage in European eel (Anguilla anguilla L.).

Journal: Ecotoxicology and environmental safety 20081101

Title: A bioassay approach to determine the dioxin-like activity in sediment extracts from the Danube River: ethoxyresorufin-O-deethylase induction in gill filaments and liver of three-spined sticklebacks (Gasterosteus aculeatus L.).

Journal: Environment international 20081101

Title: Determination of CYP activity in precision-cut liver slices: whether to use intact slices or slice homogenate.

Journal: Analytical and bioanalytical chemistry 20081101

Title: Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.

Journal: Analytical and bioanalytical chemistry 20081101

Title: Benzo[a]pyrene induces intercellular adhesion molecule-1 through a caveolae and aryl hydrocarbon receptor mediated pathway.

Journal: Toxicology and applied pharmacology 20081015

Title: Bimodal protein targeting through activation of cryptic mitochondrial targeting signals by an inducible cytosolic endoprotease.

Journal: Molecular cell 20081010

Title: Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes.

Journal: Archives of environmental contamination and toxicology 20081001

Title: Strain differences in hepatic cytochrome P450 1A and 3A expression between Sprague-Dawley and Wistar rats.

Journal: The Journal of toxicological sciences 20081001

Title: Induction of cytochromes P450 in small intestine by chemopreventive compounds.

Journal: Neuro endocrinology letters 20081001

Title: Construction of a reporter yeast strain to detect estrogen receptor signaling through aryl hydrocarbon receptor activation.

Journal: Environmental science & technology 20080915

Title: Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction.

Journal: Molecular pharmacology 20080901

Title: Biochemical markers for the assessment of aquatic environment contamination.

Journal: Interdisciplinary toxicology 20080901

Title: Inhibitory effects of a dietary phytochemical 3,3'-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080701

Title: Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements.

Journal: Biochemical pharmacology 20080701

Title: Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems.

Journal: The Journal of biological chemistry 20080620

Title: cDNA cloning and expression of a xenobiotic metabolizing cytochrome P4501A (CYP1A) from the yellow catfish, Pelteobagrus fulvidraco (Siluriformes).

Journal: Environmental toxicology 20080601

Title: 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) atropisomers interact enantioselectively with hepatic microsomal cytochrome P450 enzymes.

Journal: Chemical research in toxicology 20080601

Title: Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical.

Journal: The AAPS journal 20080601

Title: Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080530

Title: The role of metabolism in the toxicity of 2,4,6-trinitrotoluene and its degradation products to the aquatic amphipod Hyalella azteca.

Journal: Ecotoxicology and environmental safety 20080501

Title: Coordinated induction of drug transporters and phase I and II metabolism in human liver slices.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080423

Title: Brain transcriptomics in response to beta-naphthoflavone treatment in rainbow trout: the role of aryl hydrocarbon receptor signaling.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080408

Title: Biotransformation and pharmacokinetics of the novel anticancer drug, SYUIQ-5, in the rat.

Journal: Investigational new drugs 20080401

Title: Induction of metabolism and transport in human intestine: validation of precision-cut slices as a tool to study induction of drug metabolism in human intestine in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080301

Title: Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons.

Journal: Environmental health perspectives 20080301

Title: [Metabolism-based interaction of diphenytriazol and flavone compounds].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20080301

Title: Zinc nutritional status modulates expression of ahr-responsive p450 enzymes in vascular endothelial cells.

Journal: Environmental toxicology and pharmacology 20080301

Title: beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats.

Journal: Toxicology 20080227

Title: Acute and prolonged stress responses of brain monoaminergic activity and plasma cortisol levels in rainbow trout are modified by PAHs (naphthalene, beta-naphthoflavone and benzo(a)pyrene) treatment.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080218

Title: beta-Naphthoflavone and benzo(a)pyrene treatment affect liver intermediary metabolism and plasma cortisol levels in rainbow trout Oncorhynchus mykiss.

Journal: Ecotoxicology and environmental safety 20080201

Title: Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.

Journal: Biochemical pharmacology 20080201

Title: Hepatic metabolism of contaminants in the terapontid fish, yellowtail trumpeter (Amniataba caudavittata Richardson).

Journal: Environmental toxicology 20080201

Title: Humic substances modify accumulation but not biotransformation of pyrene in salmon yolk-sac fry.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080131

Title: Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo.

Journal: Archives of toxicology 20080101

Title: Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080101

Title: Molecular cloning and beta-naphthoflavone-induced expression of a cytochrome P450 1A (CYP1A) gene from an anadromous river pufferfish, Takifugu obscurus.

Journal: Marine pollution bulletin 20080101

Title: Crystalline silica is a negative modifier of pulmonary cytochrome P-4501A1 induction.

Journal: Journal of toxicology and environmental health. Part A 20080101

Title: Temporal evaluation of CYP mRNA in mice administered with prototypical P450 inducers: comparison with conventional protein/enzyme methods.

Journal: Drug and chemical toxicology 20080101

Title: Synergistic induction of AHR regulated genes in developmental toxicity from co-exposure to two model PAHs in zebrafish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20071230

Title: Aryl hydrocarbon receptor (AhR)-mediated reporter gene expression systems in transgenic tobacco plants.

Journal: Planta 20071201

Title: In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P450 inducers.

Journal: Molecular pharmacology 20071201

Title: Hepatic biomarker responses to organic contaminants in feral chub (Leuciscus cephalus)--laboratory characterization and field study in the Sava River, Croatia.

Journal: Environmental toxicology and chemistry 20071201

Title: Aryl hydrocarbon receptor signaling in rainbow trout hepatocytes: role of hsp90 and the proteasome.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20071101

Title: Inducibility of AhR-regulated CYP genes by beta-naphthoflavone in the liver, lung, kidney and heart of the pig.

Journal: Toxicology 20071030

Title: Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes.

Journal: Toxicology and applied pharmacology 20071015

Title: Induction of EROD activity by 1-phenylimidazole and beta-naphthoflavone in rainbow trout cultured hepatocytes: a comparative study.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20071001

Title: Role of nitric oxide in downregulation of cytochrome P450 1a1 and NADPH: Quinone oxidoreductase 1 by tumor necrosis factor-alpha and lipopolysaccharide.

Journal: Journal of pharmaceutical sciences 20071001

Title: Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001

Title: A noninvasive test of exposition to toxicants: quantitative analysis of cytochrome P4501A expression in fish scales.

Journal: Environmental toxicology and chemistry 20071001

Title: Stereoselective metabolism of carvedilol by the beta-naphthoflavone-inducible enzyme in human intestinal epithelial Caco-2 cells.

Journal: Biological & pharmaceutical bulletin 20071001

Title: Short-term modulation of cell proliferation and apoptosis and preventive/therapeutic efficacy of various agents in a mammary cancer model.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070915

Title: Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor.

Journal: Molecular pharmacology 20070901

Title: Presence and inducibility by beta-naphthoflavone of CYP1A1, CYP1B1 and phase II enzymes in Trematomus bernacchii, an Antarctic fish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070815

Title: A sandwich-cultured rat hepatocyte system with increased metabolic competence evaluated by gene expression profiling.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070801

Title: Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats.

Journal: Regulatory toxicology and pharmacology : RTP 20070801

Title: Hepatocytes maintain their function on basement membrane formed by epithelial cells.

Journal: Biochemical and biophysical research communications 20070720

Title: Persistent binding of ligands to the aryl hydrocarbon receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070701

Title: Conditional deletion of cytochrome P450 oxidoreductase in the liver and gastrointestinal tract: a new model for studying the functions of the P450 system.

Journal: The Journal of pharmacology and experimental therapeutics 20070701

Title: Hepatic morphological alterations, glycogen content and cytochrome P450 activities in rats treated chronically with N(omega)-nitro-L-arginine methyl ester (L-NAME).

Journal: Cell and tissue research 20070701

Title: Modulation of aryl hydrocarbon receptor transactivation by carbaryl, a nonconventional ligand.

Journal: The FEBS journal 20070701

Title: Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver.

Journal: Hepatology (Baltimore, Md.) 20070701

Title: Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture.

Journal: Planta medica 20070701

Title: Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice.

Journal: Oncogene 20070628

Title: 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.

Journal: Carcinogenesis 20070601

Title: Quinone reductase induction activity of methoxylated analogues of resveratrol.

Journal: European journal of medicinal chemistry 20070601

Title: Induction of phase I and II drug metabolism in rat small intestine and colon in vitro.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601

Title: beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells.

Journal: Biochemical pharmacology 20070515

Title: Basal and 3,3',4,4',5-pentachlorobiphenyl-induced expression of cytochrome P450 1A, 1B and 1C genes in zebrafish.

Journal: Toxicology and applied pharmacology 20070515

Title: Regulation of aryl hydrocarbon receptor activity in porcine cumulus-oocyte complexes in physiological and toxicological conditions: the role of follicular fluid.

Journal: Reproduction (Cambridge, England) 20070501

Title: Environmental monitoring by gene expression biomarkers in Barbus graellsii: laboratory and field studies.

Journal: Chemosphere 20070401

Title: Metabolism of a heterocyclic amine colon carcinogen in young and old rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070401

Title: Development of three parallel cytochrome P450 enzyme affinity detection systems coupled on-line to gradient high-performance liquid chromatography.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070401

Title: Development of a Daphnia magna DNA microarray for evaluating the toxicity of environmental chemicals.

Journal: Environmental toxicology and chemistry 20070401

Title: Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070330

Title: Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice.

Journal: The Journal of biological chemistry 20070323

Title: Identification of amino acid residues in the Ah receptor involved in ligand binding.

Journal: Biochemical and biophysical research communications 20070309

Title: Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver.

Journal: Archives of toxicology 20070301

Title: Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation.

Journal: Carcinogenesis 20070301

Title: Determination of phospholipidosis potential based on gene expression analysis in HepG2 cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070301

Title: Cytochrome P450 1A expression and organochlorine contaminants in harbour seals (Phoca vitulina): evaluating a biopsy approach.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070301

Title: Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis.

Journal: Journal of natural products 20070301

Title: Metabolic enzyme induction by HepG2 cells exposed to oxygenated and nonoxygenated polycyclic aromatic hydrocarbons.

Journal: Chemical research in toxicology 20070201

Title: Isolation and identification of xenobiotic aryl hydrocarbon receptor ligands in dyeing wastewater.

Journal: Environmental science & technology 20070115

Title: Significant transcriptional down-regulation of the human MDR1 gene by beta-naphthoflavone: a proposed hypothesis linking potent CYP gene induction to MDR1 inhibition.

Journal: Medical hypotheses 20070101

Title: Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070101

Title: Interactions between estrogen- and Ah-receptor signalling pathways in primary culture of salmon hepatocytes exposed to nonylphenol and 3,3',4,4'-tetrachlorobiphenyl (congener 77).

Journal: Comparative hepatology 20070101

Title: Establishment of rat precision-cut fibrotic liver slice technique and its application in verapamil metabolism.

Journal: Clinical and experimental pharmacology & physiology 20070101

Title: Complementary DNA cloning and organ expression of cytochrome P450 1C2 in carp (Cyprinus carpio).

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20070101

Title: Vitellogenin, zona radiata protein, cathepsin D and heat shock protein 70 as biomarkers of exposure to xenobiotics.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20070101

Title: Sensitive and robust gene expression changes in fish exposed to estrogen--a microarray approach.

Journal: BMC genomics 20070101

Title: Effect of cytochrome P450 (CYP) inducers on caffeine metabolism in the rat.

Journal: Pharmacological reports : PR 20070101

Title: H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: Spatial transcription of CYP1A in fish liver.

Journal: BMC physiology 20070101

Title: Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by Benzo(alpha)pyrene and 2-aminofluorene metabolites.

Journal: Immunopharmacology and immunotoxicology 20070101

Title: The effect of aryl hydrocarbon receptor ligands on the expression of AhR, AhRR, ARNT, Hif1alpha, CYP1A1 and NQO1 genes in rat liver.

Journal: Toxicology letters 20061215

Title: Oxidative stress, liver biotransformation and genotoxic effects induced by copper in Anguilla anguilla L.--the influence of pre-exposure to beta-naphthoflavone.

Journal: Chemosphere 20061201

Title: Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061201

Title: Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family.

Journal: The Biochemical journal 20061201

Title: Differentiation-specific factors modulate epidermal CYP1-4 gene expression in human skin in response to retinoic acid and classic aryl hydrocarbon receptor ligands.

Journal: The Journal of pharmacology and experimental therapeutics 20061201

Title: Endogenous hepatic expression of the hepatitis B virus X-associated protein 2 is adequate for maximal association with aryl hydrocarbon receptor-90-kDa heat shock protein complexes.

Journal: Molecular pharmacology 20061201

Title: Toxicological aspects of flavonoid interaction with biomacromolecules.

Journal: Neuro endocrinology letters 20061201

Title: Activation of the aryl hydrocarbon receptor by carbaryl: Computational evidence of the ability of carbaryl to assume a planar conformation.

Journal: Environmental toxicology and chemistry 20061201

Title: Evaluation of human CYP1A2 and CYP3A4 mRNA expression in hepatocytes from chimeric mice with humanized liver.

Journal: Drug metabolism and pharmacokinetics 20061201

Title: Comparative in vitro metabolism of benzo[a]pyrene by recombinant zebrafish CYP1A and liver microsomes from beta-naphthoflavone-treated rainbow trout.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20061116

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Influence of salinity and fish species on PAH uptake from dispersed crude oil.

Journal: Marine pollution bulletin 20061001

Title: Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20061001

Title: Evaluating cytochrome p450 in lesser scaup (Aythya affinis) and tree swallow (Tachycineta bicolor) by monooxygenase activity and immunohistochemistry: possible nonlethal assessment by skin immunohistochemistry.

Journal: Environmental toxicology and chemistry 20061001

Title: Bifunctional modulating effects of an indigo dimer (bisindigotin) to CYP1A1 induction in H4IIE cells.

Journal: Toxicology 20060921

Title: Oxidative stress and genotoxic effects in gill and kidney of Anguilla anguilla L. exposed to chromium with or without pre-exposure to beta-naphthoflavone.

Journal: Mutation research 20060919

Title: Regulation of aryl hydrocarbon receptor expression in rat granulosa cells.

Journal: Biology of reproduction 20060901

Title: Regulation of the CYP1A1 gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin but not by beta-naphthoflavone or 3-methylcholanthrene is altered in hepatitis C virus replicon-expressing cells.

Journal: Molecular pharmacology 20060901

Title: Apoptosis and Bax expression are increased by coal dust in the polycyclic aromatic hydrocarbon-exposed lung.

Journal: Environmental health perspectives 20060901

Title: [Tissue-like cultures of rat hepatocytes in study of phase I and phase II drug metabolism].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20060901

Title: Effects of copper on CYP1A activity and epithelial barrier properties in the rainbow trout gill.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060812

Title: Inducibility of UDP-glucuronosyltransferase 1As by beta-naphthoflavone in HepG2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060801

Title: The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801

Title: Non destructive in vivo measurement of ethoxyresorufin biotransformation by zebrafish prolarva: development and application.

Journal: Environmental toxicology 20060801

Title: PAH-DNA adducts in cord blood and fetal and child development in a Chinese cohort.

Journal: Environmental health perspectives 20060801

Title: Induction of 26S proteasome subunit PSMB5 by the bifunctional inducer 3-methylcholanthrene through the Nrf2-ARE, but not the AhR/Arnt-XRE, pathway.

Journal: Biochemical and biophysical research communications 20060714

Title: Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducers.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060701

Title: Evaluating the interactions of vertebrate receptors with persistent pollutants and antifouling pesticides using recombinant yeast assays.

Journal: Analytical and bioanalytical chemistry 20060701

Title: A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.

Journal: Molecular pharmacology 20060601

Title: Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601

Title: Resveratrol affects CYP1A expression in rainbow trout hepatocytes.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060510

Title: Antitumor activity of some natural flavonoids and synthetic derivatives on various human and murine cancer cell lines.

Journal: Bioorganic & medicinal chemistry 20060501

Title: Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene.

Journal: The Biochemical journal 20060501

Title: The aspirin metabolite, salicylate, inhibits 7,12-dimethylbenz[a]anthracene-DNA adduct formation in breast cancer cells.

Journal: International journal of oncology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: In vitro investigations on the differential pro-oxidant and/or antioxidant properties of cyclosporin A and tacrolimus in human and rat liver microsomes.

Journal: International journal of clinical pharmacology and therapeutics 20060501

Title: Enhancing the drug metabolism activities of C3A--a human hepatocyte cell line--by tissue engineering within alginate scaffolds.

Journal: Tissue engineering 20060501

Title: Intestinal bioavailability and biotransformation of 3,3',4,4'-tetrachlorobiphenyl (CB 77) in in situ preparations of channel catfish following dietary induction of CYP1A.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060420

Title: Aryl hydrocarbon receptor activation impairs cortisol response to stress in rainbow trout by disrupting the rate-limiting steps in steroidogenesis.

Journal: Endocrinology 20060401

Title: Early loss of Fhit in the respiratory tract of rodents exposed to environmental cigarette smoke.

Journal: Cancer research 20060401

Title: Cytochrome P4501A is induced in endothelial cell lines from the kidney and lung of the bottlenose dolphin, Tursiops truncatus.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060310

Title: Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060301

Title: Propagation and functional characterization of serum-free cultured porcine hepatocytes for downstream applications.

Journal: Cell and tissue research 20060301

Title: Role of rat liver cytochrome P450 3A and 2D in metabolism of imrecoxib.

Journal: Acta pharmacologica Sinica 20060301

Title: Development of a toxicogenomics in vitro assay for the efficient characterization of compounds.

Journal: Pharmacogenomics 20060301

Title: Bioactive dammarane triterpenes from the mangrove plant Bruguiera gymnorrhiza.

Journal: Journal of natural products 20060301

Title: Developmental and behavioral effects of embryonic exposure to the polybrominated diphenylether mixture DE-71 in the killifish (Fundulus heteroclitus).

Journal: Chemosphere 20060201

Title: An in vivo and in vitro comparison of CYP gene induction in mice using liver slices and quantitative RT-PCR.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20060201

Title: An aryl hydrocarbon receptor agonist amplifies the mitogenic actions of estradiol in granulosa cells: evidence of involvement of the cognate receptors.

Journal: Biology of reproduction 20060201

Title: Aryl hydrocarbon receptor activation inhibits regenerative growth.

Journal: Molecular pharmacology 20060101

Title: Cytochrome P450 expression-induction profile and chemically mediated alterations of the WIF-B9 cell line.

Journal: Biology of the cell 20060101

Title: Modest induction of phase 2 enzyme activity in the F-344 rat prostate.

Journal: BMC cancer 20060101

Title: Temporal kinetics and concentration-response relationships for induction of CYP1A, CYP2B, and CYP3A in primary cultures of beagle dog hepatocytes.

Journal: Journal of biochemical and molecular toxicology 20060101

Title: Beta-naphthoflavone represses dystrophin Dp71 expression in hepatic cells.

Journal: Biochimica et biophysica acta 20060101

Title: Development of a recombinant yeast assay to detect ah-receptor ligands.

Journal: Toxicology mechanisms and methods 20060101

Title: Modulation of multigene expression and proteome profiles by chemopreventive agents.

Journal: Mutation research 20051211

Title: Modulation of apoptosis by cancer chemopreventive agents.

Journal: Mutation research 20051211

Title: Bioassay-based screening of microorganisms that degrade dioxin using substrate-immobilized microtubes.

Journal: Analytical biochemistry 20051201

Title: The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo.

Journal: Carcinogenesis 20051101

Title: Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101

Title: Cytosolic persistence of mouse brain CYP1A1 in chronic heme deficiency.

Journal: Biological chemistry 20051101

Title: Cytochrome P4501A induction caused by the imidazole derivative Prochloraz in a rainbow trout cell line.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20051001

Title: Expression profiling of five different xenobiotics using a Caenorhabditis elegans whole genome microarray.

Journal: Chemosphere 20051001

Title: Anguilla anguilla L. oxidative stress biomarkers responses to copper exposure with or without beta-naphthoflavone pre-exposure.

Journal: Chemosphere 20051001

Title: Effects of the polycyclic aromatic hydrocarbon heterocycles, carbazole and dibenzothiophene, on in vivo and in vitro CYP1A activity and polycyclic aromatic hydrocarbon-derived embryonic deformities.

Journal: Environmental toxicology and chemistry 20051001

Title: The spectrum of enzymes involved in activation of 2-aminoanthracene varies with the metabolic system applied.

Journal: Mutation research 20050905

Title: Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050901

Title: Attenuation of hyperoxic lung injury by the CYP1A inducer beta-naphthoflavone.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050901

Title: Assessment of cytochrome P450 1A in harbour seals (Phoca vitulina) using a minimally-invasive biopsy approach.

Journal: Marine environmental research 20050801

Title: Functional analysis of six human aryl hydrocarbon receptor variants in a Japanese population.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801

Title: CYP1A1 and CYP1B1 expressions in medulloblastoma cells are AhR-independent and have no direct link with resveratrol-induced differentiation and apoptosis.

Journal: Neuroscience letters 20050801

Title: Development of a novel cytochrome p450 bioaffinity detection system coupled online to gradient reversed-phase high-performance liquid chromatography.

Journal: Journal of biomolecular screening 20050801

Title: Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701

Title: A non-lethal method to estimate CYP1A expression in laboratory and wild Atlantic salmon (Salmo salar).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050701

Title: Content of 8-hydroxy-2-deoxyguanosine in steroid receptor-positive and receptor-negative breast cancer cells.

Journal: Bulletin of experimental biology and medicine 20050701

Title: Convenient syntheses of dibenzo[c,p]chrysene and its possible proximate and ultimate carcinogens: in vitro metabolism and DNA adduction studies.

Journal: The Journal of organic chemistry 20050624

Title: Modulation of Ah receptor and CYP1A1 expression by alpha-naphthoflavone in rainbow trout hepatocytes.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050501

Title: Determination of zolmitriptan enantiomers in rat liver microsomes by chiral high performance liquid chromatography with fl uorescence detection.

Journal: Biomedical chromatography : BMC 20050401

Title: Ah Receptor-mediated impairment of interrenal steroidogenesis involves StAR protein and P450scc gene attenuation in rainbow trout.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050401

Title: Induction of human CYP1A2 and CYP3A4 in primary culture of hepatocytes from chimeric mice with humanized liver.

Journal: Drug metabolism and pharmacokinetics 20050401

Title: Involvement of SULT1A3 in elevated sulfation of 4-hydroxypropranolol in Hep G2 cells pretreated with beta-naphthoflavone.

Journal: Biochemical pharmacology 20050315

Title: Down-regulation of aryl hydrocarbon receptor-regulated genes by tumor necrosis factor-alpha and lipopolysaccharide in murine hepatoma Hepa 1c1c7 cells.

Journal: Journal of pharmaceutical sciences 20050301

Title: Reductase-mediated metabolism of motexafin gadolinium (Xcytrin) in rat and human liver subcellular fractions and purified enzyme preparations.

Journal: Journal of pharmaceutical sciences 20050301

Title: Stereoselectivity and interaction between the glucuronidation of S-(-)- and R-(+)-propranolol in rat hepatic microsomes pretreated with different inducers.

Journal: Die Pharmazie 20050301

Title: Effects of TCDD and estradiol-17beta on the proliferation and Na+/glucose cotransporter in renal proximal tubule cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20050201

Title: Fast-track DRESSA: a bioassay for fast, sensitive, and selective detection of halogenated and polycyclic aromatic hydrocarbons.

Journal: Analytical biochemistry 20050201

Title: Physiological and genetic responses of European eel (Anguilla anguilla L.) to short-term chromium or copper exposure-Influence of preexposure to a PAH-like compound.

Journal: Environmental toxicology 20050201

Title: A microtiterplate-based screening assay to assess diverse effects on cytochrome P450 enzyme activities in primary rat hepatocytes by various compounds.

Journal: Assay and drug development technologies 20050201

Title: Histomorphological changes and cytochrome P450 isoforms expression and activities in precision-cut liver slices from neonatal rats.

Journal: Toxicology 20050131

Title: Contaminants as viral cofactors: assessing indirect population effects.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20050118

Title: Cytochrome P450 expression and activities in human tongue cells and their modulation by green tea extract.

Journal: Toxicology and applied pharmacology 20050115

Title: Lack of evidence for induction of CYP2B1, CYP3A23, and CYP1A2 gene expression by Panax ginseng and Panax quinquefolius extracts in adult rats and primary cultures of rat hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101

Title: Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.

Journal: Biomedical chromatography : BMC 20050101

Title: Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast.

Journal: The Journal of clinical endocrinology and metabolism 20050101

Title: Preparation of trout liver microsomes for iron speciation in P-450 enzymes by AE-FPLC with ICP-(ORS)MS detection.

Journal: Analytical and bioanalytical chemistry 20050101

Title: Endocrine and metabolic changes in Anguilla anguilla L. following exposure to beta-naphthoflavone--a microsomal enzyme inducer.

Journal: Environment international 20050101

Title: Transcription factor Nrf2 regulates promoter activity of mouse aldose reductase (AKR1B3) gene.

Journal: Journal of pharmacological sciences 20050101

Title: Effect of beta-naphthoflavone and phenobarbital on the nephrotoxicity of chlorotrifluoroethylene and 1,1-dichloro-2,2-difluoroethylene in the rat.

Journal: Journal of applied toxicology : JAT 20050101

Title: Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers.

Journal: Journal of biochemical and molecular toxicology 20050101

Title: Effects of redox cycling compounds on DT diaphorase activity in the liver of rainbow trout (Oncorhynchus mykiss).

Journal: Comparative hepatology 20050101

Title: Complementary DNA cloning and constitutive expression of cytochrome P450 1C1 in the gills of carp (Cyprinus carpio).

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20050101

Title: Cytochrome p4501a induced differentially in endothelial cells cultured from different organs of Anguilla rostrata.

Journal: In vitro cellular & developmental biology. Animal 20050101

Title: Suppression of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis by pre-initiation treatment of rats with beta-naphthoflavone coincides with decreased levels of the carcinogen-derived DNA adducts in the mammary gland.

Journal: Cancer detection and prevention 20050101

Title: Beta-naphthoflavone inhibits the induction of hepatic oestrogen-dependent proteins by 17alpha-ethynylestradiol in mosquitofish (Gambusia holbrooki).

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20050101

Title: The role of Ah receptor in induction of human UDP-glucuronosyltransferase 1A1.

Journal: Methods in enzymology 20050101

Title: An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCR.

Journal: Chemico-biological interactions 20041230

Title: Induction of cytochrome P4501A (CYP1A) by clotrimazole, a non-planar aromatic compound. Computational studies on structural features of clotrimazole and related imidazole derivatives.

Journal: Life sciences 20041224

Title: Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20041201

Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces suppressor of cytokine signaling 2 in murine B cells.

Journal: Molecular pharmacology 20041201

Title: DRESSA: biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase.

Journal: Analytical biochemistry 20041201

Title: Synergistic embryotoxicity of polycyclic aromatic hydrocarbon aryl hydrocarbon receptor agonists with cytochrome P4501A inhibitors in Fundulus heteroclitus.

Journal: Environmental health perspectives 20041201

Title: Modulation of the hepatic CYP1A1 system in the marine fish Gobius niger, exposed to xenobiotic compounds.

Journal: Environmental science & technology 20041201

Title: A Cyp1a2-luciferase transgenic CD-1 mouse model: responses to aryl hydrocarbons similar to the humanized AhR mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041101

Title: In vitro and in vivo comparisons of fish-specific CYP1A induction relative potency factors for selected polycyclic aromatic hydrocarbons.

Journal: Ecotoxicology and environmental safety 20041101

Title: Oil dispersant increases PAH uptake by fish exposed to crude oil.

Journal: Ecotoxicology and environmental safety 20041101

Title: Barramundi as an indicator species for environmental monitoring in North Queensland, Australia: laboratory versus field studies.

Journal: Environmental toxicology and chemistry 20041101

Title: Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway.

Journal: Free radical research 20041101

Title: Expression and induction of cytochromes p450 in rat white adipose tissue.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: Juvenile sea bass biotransformation, genotoxic and endocrine responses to beta-naphthoflavone, 4-nonylphenol and 17 beta-estradiol individual and combined exposures.

Journal: Chemosphere 20041001

Title: Modulation of aryl hydrocarbon receptor-regulated gene expression by arsenite, cadmium, and chromium.

Journal: Toxicology 20041001

Title: The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes.

Journal: Toxicology and applied pharmacology 20040915

Title: Comparison of the induction of a 4S beta-naphthoflavone-binding protein, cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in beta-naphthoflavone-treated rats.

Journal: Toxicology letters 20040910

Title: Differential effects of mercury, lead and copper on the constitutive and inducible expression of aryl hydrocarbon receptor (AHR)-regulated genes in cultured hepatoma Hepa 1c1c7 cells.

Journal: Toxicology 20040901

Title: Effects of beta-naphthoflavone, phenobarbital and dichlobenil on the drug-metabolizing system of liver and nasal mucosa of Italian water frogs.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040825

Title: Induction of cetacean cytochrome P4501A1 by beta-naphthoflavone exposure of skin biopsy slices.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040801

Title: Respirable coal dust particles modify cytochrome P4501A1 (CYP1A1) expression in rat alveolar cells.

Journal: American journal of respiratory cell and molecular biology 20040801

Title: Beta-naphthoflavone disturbs astrocytic differentiation of C6 glioma cells by inhibiting autocrine interleukin-6.

Journal: Journal of neurochemistry 20040801

Title: 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.

Journal: Chemical research in toxicology 20040801

Title: Specific interactions of steroids, arylhydrocarbons and flavonoids with progesterone receptors from the cytosol of the fungus Rhizopus nigricans.

Journal: The Journal of steroid biochemistry and molecular biology 20040801

Title: Blarina brevicauda as a biological monitor of polychlorinated biphenyls: evaluation of hepatic cytochrome P450 induction.

Journal: Environmental toxicology and chemistry 20040801

Title: Selectivity of 7-alkoxycoumarins as probe substrates for rat hepatic cytochrome P450 forms is influenced by the substitution pattern on the coumarin nucleus.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040801

Title: Metabolic and structural viability of precision-cut rat lung slices in culture.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040801

Title: Response of rainbow trout transcriptome to model chemical contaminants.

Journal: Biochemical and biophysical research communications 20040730

Title: Glucuronidation of 1-naphthol and excretion into the vein in perfused rat kidney.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701

Title: Glutathione protects heavy metal-induced inhibition of hepatic microsomal ethoxyresorufin O-deethylase activity in Dicentrarchus labrax L.

Journal: Ecotoxicology and environmental safety 20040701

Title: In vitro biotransformation of 3,4-dihydro-6-hydroxy-2,2-dimethyl-7-methoxy-1(2H)-benzopyran (CR-6), a potent lipid peroxidation inhibitor and nitric oxide scavenger, in rat liver microsomes.

Journal: Chemical research in toxicology 20040701

Title: Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc.

Journal: The Biochemical journal 20040615

Title: Metabolic activation of troglitazone: identification of a reactive metabolite and mechanisms involved.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040601

Title: Beta-naphthoflavone alters normal plasma levels of vitellogenin, 17 beta-estradiol and luteinizing hormone in sea bass broodstock.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040512

Title: Influence of recipient gender on intrasplenic fetal liver tissue transplants in rats: cytochrome P450-mediated monooxygenase functions.

Journal: Toxicology 20040503

Title: Comparative study in the Ames test of benzo[a]pyrene and 2-aminoanthracene metabolic activation using rat hepatic S9 and hepatocytes following in vivo or in vitro induction.

Journal: Mutagenesis 20040501

Title: Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin.

Journal: Gastroenterology 20040501

Title: Retionic acid and its receptors are required for expression of aryl hydrocarbon receptor mRNA and embryonic development of blood vessel and bone in the medaka fish, Oryzias latipes.

Journal: Zoological science 20040501

Title: beta-Naphthoflavone disrupts cortisol production and liver glucocorticoid responsiveness in rainbow trout.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040428

Title: Comparison of four modulators of drug metabolism as protectants against the hepatotoxicity of the novel antitumor drug yondelis (ET-743) in the female rat and in hepatocytes in vitro.

Journal: Cancer chemotherapy and pharmacology 20040401

Title: Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line.

Journal: The Journal of pharmacology and experimental therapeutics 20040401

Title: Functional characterization of aryl hydrocarbon receptor (zfAHR2) localization and degradation in zebrafish (Danio rerio).

Journal: Biochemical pharmacology 20040401

Title: beta-naphthoflavone induction of CYP1A in brain of juvenile lake trout (Salvelinus namaycush Walbaum).

Journal: The Journal of experimental biology 20040401

Title: Induction of diphenytriazol on cytochrome CYP1A.

Journal: Acta pharmacologica Sinica 20040401

Title: Cell-specific CYP1A expression and benzo[a]pyrene adduct formation in gills of rainbow trout (Oncorhynchus mykiss) following CYP1A induction in the laboratory and in the field.

Journal: Environmental toxicology and chemistry 20040401

Title: Molecular cloning of cytochrome P4501A cDNA of medaka (Oryzias latipes) and messenger ribonucleic acid regulation by environmental pollutants.

Journal: Environmental toxicology and chemistry 20040401

Title: In vitro metabolism and inductive or inhibitive effect of DL111 on rat cytochrome P4501A enzyme.

Journal: Chemico-biological interactions 20040315

Title: Development and application of a real-time quantitative PCR assay for determining CYP1A transcripts in three genera of salmonids.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040310

Title: Cooperation of heat shock protein 90 and p23 in aryl hydrocarbon receptor signaling.

Journal: Cell stress & chaperones 20040301

Title: Antiandrogenic activity of extracts of diesel exhaust particles emitted from diesel-engine truck under different engine loads and speeds.

Journal: Toxicology 20040215

Title: Characterization of enzymes responsible for biotransformation of the new antileukotrienic drug quinlukast in rat liver microsomes and in primary cultures of rat hepatocytes.

Journal: The Journal of pharmacy and pharmacology 20040201

Title: The effects of diet composition and ration on biotransformation enzymes and stress parameters in rainbow trout, Oncorhynchus mykiss.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20040201

Title: Antiproliferative activity of various flavonoids and related compounds: additive effect of interferon-alpha2b.

Journal: Bioorganic & medicinal chemistry letters 20040105

Title: An electrochemical device for the assay of the interaction between a dioxin receptor and its various ligands.

Journal: Bioorganic & medicinal chemistry letters 20040105

Title: Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction.

Journal: The Biochemical journal 20040101

Title: [Interaction between ipriflavone and other drugs in metabolism in vitro].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040101

Title: Evaluation of a real-time polymerase chain reaction method for the quantification of CYP1B1 gene expression in MCF-7 human breast carcinoma cells.

Journal: Journal of pharmacological and toxicological methods 20040101

Title: Effect of Ginkgo biloba extract on rat hepatic microsomal CYP1A activity: role of ginkgolides, bilobalide, and flavonols.

Journal: Canadian journal of physiology and pharmacology 20040101

Title: Identification and induction by beta-naphthoflavone of CYP1A1 in liver of the neotropical fish pacu, Piaractus mesopotamicus (Characiformes: characidae).

Journal: Bulletin of environmental contamination and toxicology 20040101

Title: Effects of beta-naphthoflavone on hepatic biotransformation and glutathione biosynthesis in largemouth bass (Micropterus salmoides).

Journal: Marine environmental research 20040101

Title: Endothelial cell cytochrome P450 1A1 and 1B1: up-regulation by shear stress.

Journal: Endothelium : journal of endothelial cell research 20040101

Title: In vitro metabolism of zolmitriptan in rat cytochromes induced with beta-naphthoflavone and the interaction between six drugs and zolmitriptan.

Journal: Chemico-biological interactions 20031215

Title: Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031101

Title: Alpha-naphthoflavone induces vasorelaxation through the induction of extracellular calcium influx and NO formation in endothelium.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031101

Title: Characterization of mouse small intestinal cytochrome P450 expression.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101

Title: EROD activity in gill filaments of anadromous and marine fish as a biomarker of dioxin-like pollutants.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031101

Title: Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031001

Title: Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories.

Journal: Environmental toxicology and chemistry 20031001

Title: Constitutive and inducible levels of CYP1A1 and CYP1A2 in rat cerebral cortex and cerebellum.

Journal: Archives of toxicology 20031001

Title: Construction of reporter yeasts for mouse aryl hydrocarbon receptor ligand activity.

Journal: Mutation research 20030909

Title: 7,8-Benzoflavone: a phytotoxin from root exudates of invasive Russian knapweed.

Journal: Phytochemistry 20030901

Title: Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells.

Journal: Biochemical pharmacology 20030901

Title: Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element.

Journal: The Journal of nutrition 20030901

Title: Integrating enzymatic responses to organic chemical exposure with total oxyradical absorbing capacity and DNA damage in the European eel Anguilla anguilla.

Journal: Environmental toxicology and chemistry 20030901

Title: Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR.

Journal: Pharmaceutical research 20030901

Title: Roles of human CYP2A6 and 2B6 and rat CYP2C11 and 2B1 in the 10-hydroxylation of (-)-verbenone by liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030801

Title: Aqueous outflow-enhancing effect of tert-butylhydroquinone: involvement of AP-1 activation and MMP-3 expression.

Journal: Investigative ophthalmology & visual science 20030801

Title: Induction of EROD activity in European eel (Anguilla anguilla) experimentally exposed to benzo[a]pyrene and beta-naphthoflavone.

Journal: Environment international 20030701

Title: Induction of P450 monooxygenases in the German cockroach, Blattella germanica L.

Journal: Archives of insect biochemistry and physiology 20030701

Title: Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents.

Journal: Biochemical pharmacology 20030701

Title: Cocaine-protein targets in mouse liver.

Journal: Biochemical pharmacology 20030701

Title: Effects of dimethyl sulfoxide on the gene induction of cytochrome P450 isoforms, UGT-dependent glucuronosyl transferase isoforms, and ABCB1 in primary culture of human hepatocytes.

Journal: Biological & pharmaceutical bulletin 20030701

Title: Use of cultured precision-cut rat lung slices to study the in vitro induction of pulmonary cytochrome P450 forms.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030701

Title: Influence of recipient gender on cytochrome P450 isoforms expression in intrasplenic fetal liver tissue transplants in rats.

Journal: Toxicology 20030630

Title: Influence of propiverine on hepatic microsomal cytochrome p450 enzymes in male rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030601

Title: Upregulation of cytochromes P450 2B in rat liver by orphenadrine.

Journal: British journal of pharmacology 20030601

Title: Glucuronidation of 4-methylumbelliferone and 4-hydroxybiphenyl and in vitro induction of UDP-glucuronosyltransferase 2B12-mRNA in precision-cut rat liver slices.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601

Title: Anguilla anguilla L. liver ethoxyresorufin O-deethylation, glutathione S-transferase, erythrocytic nuclear abnormalities, and endocrine responses to naphthalene and beta-naphthoflavone.

Journal: Ecotoxicology and environmental safety 20030501

Title: Exposure to xenobiotic compounds: looking for new biomarkers.

Journal: General and comparative endocrinology 20030501

Title: Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030501

Title: Binding of polychlorinated biphenyls/metabolites to hemoglobin.

Journal: Toxicology letters 20030430

Title: Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1.

Journal: The Journal of biological chemistry 20030425

Title: Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.

Journal: Life sciences 20030404

Title: Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030401

Title: Precision-cut tissue slices from transgenic mice as an in vitro toxicology system.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030401

Title: Induction of CYP1A by the N-imidazole derivative, 1-benzylimidazole.

Journal: Environmental toxicology and chemistry 20030401

Title: Simultaneous analysis of naphthols, phenanthrols, and 1-hydroxypyrene in urine as biomarkers of polycyclic aromatic hydrocarbon exposure: intraindividual variance in the urinary metabolite excretion profiles caused by intervention with beta-naphthoflavone induction in the rat.

Journal: Archives of toxicology 20030401

Title: CYP1A1 and CYP1B1 in blood-brain interfaces: CYP1A1-dependent bioactivation of 7,12-dimethylbenz(a)anthracene in endothelial cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030301

Title: Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030301

Title: The effects of stress on the association between hsp70 and the glucocorticoid receptor in rainbow trout.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030301

Title: CYP450- and COMT-derived estradiol metabolites inhibit activity of human coronary artery SMCs.

Journal: Hypertension (Dallas, Tex. : 1979) 20030301

Title: Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.

Journal: The Journal of biological chemistry 20030214

Title: Agonist but not antagonist ligands induce conformational change in the mouse aryl hydrocarbon receptor as detected by partial proteolysis.

Journal: Molecular pharmacology 20030201

Title: Influence of omeprazole on multidrug resistance protein 3 expression in human liver.

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: Time-dependent transcriptional induction of CYP1A1, CYP1A2 and CYP1B1 mRNAs by H+/K+ -ATPase inhibitors and other xenobiotics.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030201

Title: Use of human liver S9 in the Ames test: assay of three procarcinogens using human S9 derived from multiple donors.

Journal: Regulatory toxicology and pharmacology : RTP 20030201

Title: Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones.

Journal: The Journal of biological chemistry 20030124

Title: Quantitative PCR analysis of CYP1A induction in Atlantic salmon (Salmo salar).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20030110

Title: Human intestinal Caco-2 cells display active transport of benzo[a]pyrene metabolites.

Journal: Chemico-biological interactions 20030106

Title: Preclinical factors influencing the relative contributions of Phase I and II enzymes to the metabolism of the experimental anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid.

Journal: Biochemical pharmacology 20030101

Title: The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line.

Journal: Placenta 20030101

Title: Mechanism-based in vitro screening of potential cancer chemopreventive agents.

Journal: Mutation research 20030101

Title: Modulation of cigarette smoke-related end-points in mutagenesis and carcinogenesis.

Journal: Mutation research 20030101

Title: Effects of treatment of rats with indole-3-carbinol on apoptosis in the mammary gland and mammary adenocarcinomas.

Journal: Anticancer research 20030101

Title: Evaluation of 2-year-old intrasplenic fetal liver tissue transplants in rats.

Journal: Cell transplantation 20030101

Title: Cryopreserved human hepatocytes as alternative in vitro model for cytochrome p450 induction studies.

Journal: In vitro cellular & developmental biology. Animal 20030101

Title: Cryopreserved precision-cut rat liver slices: morphology and cytochrome P450 isoforms expression after prolonged incubation.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20021201

Title: Complementary DNA cloning, sequence analysis and differential organ expression of beta-naphthoflavone-inducible cytochrome P4501A in Atlantic salmon (Salmo salar).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20021201

Title: Characterization and identification of cytochrome P450 metabolites of arachidonic acid released by human peritoneal macrophages obtained from the pouch of Douglas.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20021201

Title: Constitutive and TCDD-induced expression of Ah receptor-responsive genes in the pituitary.

Journal: Neurotoxicology 20021201

Title: A binary screening assay for pro-oestrogens in food: metabolic activation using hepatic microsomes and detection with oestrogen sensitive recombinant yeast cells.

Journal: Food additives and contaminants 20021201

Title: Effects of redox cycling compounds on glutathione content and activity of glutathione-related enzymes in rainbow trout liver.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20021101

Title: Astaxanthin and canthaxanthin do not induce liver or kidney xenobiotic-metabolizing enzymes in rainbow trout (Oncorhynchus mykiss Walbaum).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20021101

Title: In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021101

Title: Diesel exhaust particle extracts and associated polycyclic aromatic hydrocarbons inhibit Cox-2-dependent prostaglandin synthesis in murine macrophages and fibroblasts.

Journal: The Journal of biological chemistry 20021018

Title: In vitro and in vivo formation of aminophenylnorharman from norharman and aniline.

Journal: Mutation research 20020930

Title: Altering cytochrome P4501A activity affects polycyclic aromatic hydrocarbon metabolism and toxicity in rainbow trout (Oncorhynchus mykiss).

Journal: Environmental toxicology and chemistry 20020901

Title: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the zebrafish embryo: local circulation failure in the dorsal midbrain is associated with increased apoptosis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020901

Title: Naphthalene and beta-naphthoflavone effects on Anguilla anguilla L. hepatic metabolism and erythrocytic nuclear abnormalities.

Journal: Environment international 20020901

Title: Benzo[a]pyrene and beta-naphthoflavone mutagenic activation by European eel (Anguilla anguilla L.) S9 liver fraction.

Journal: Ecotoxicology and environmental safety 20020901

Title: DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique.

Journal: Chemico-biological interactions 20020815

Title: Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.

Journal: Biochemical and biophysical research communications 20020809

Title: The zebrafish (Danio rerio) aryl hydrocarbon receptor type 1 is a novel vertebrate receptor.

Journal: Molecular pharmacology 20020801

Title: Gill filament-based EROD assay for monitoring waterborne dioxin-like pollutants in fish.

Journal: Environmental science & technology 20020801

Title: Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020701

Title: [RP-HPLC determination of diphenytriazol in rat liver microsomal incubates and its application in in vitro metabolism].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020601

Title: Calcium influx factor from cytochrome P-450 metabolism and secretion-like coupling mechanisms for capacitative calcium entry in corneal endothelial cells.

Journal: The Journal of biological chemistry 20020510

Title: beta-naphthoflavone, an inducer of xenobiotic metabolizing enzymes, inhibits firefly luciferase activity.

Journal: Analytical biochemistry 20020501

Title: Tissue-specific regulation of canine intestinal and hepatic phenol and morphine UDP-glucuronosyltransferases by beta-naphthoflavone in comparison with humans.

Journal: Biochemical pharmacology 20020501

Title: Liver phase I and phase II enzymatic induction and genotoxic responses of beta-naphthoflavone water-exposed sea bass.

Journal: Ecotoxicology and environmental safety 20020501

Title: Beta-naphthoflavone liver EROD and erythrocytic nuclear abnormality induction in juvenile Dicentrarchus labrax L.

Journal: Ecotoxicology and environmental safety 20020501

Title: The p23 co-chaperone facilitates dioxin receptor signaling in a yeast model system.

Journal: Toxicology letters 20020324

Title: Glucuronidation of acetaminophen catalyzed by multiple rat phenol UDP-glucuronosyltransferases.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020301

Title: Identification of a new mutagenic polychlorinated biphenyl derivative in the Waka River, Wakayama, Japan, showing activation of an aryl hydrocarbon receptor-dependent transcription.

Journal: Chemical research in toxicology 20020301

Title: Expression of HSP70 and CYP1A protein in ovary and liver of juvenile rainbow trout exposed to beta-naphthoflavone.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020301

Title: Expression and inducibility of cytochrome P450 isoforms in 1-year-old intrasplenic liver cell transplants in rats.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20020301

Title: Effects of lactic acid bacteria on the uptake and distribution of the food mutagen Trp-P-2 in mice.

Journal: Scandinavian journal of gastroenterology 20020201

Title: Juvenile sea bass liver P450, EROD induction, and erythrocytic genotoxic responses to PAH and PAH-like compounds.

Journal: Ecotoxicology and environmental safety 20020201

Title: Influence of t-butylhydroquinone and beta-naphthoflavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/TC-7 cell monolayers.

Journal: Biochemical pharmacology 20020115

Title: CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101

Title: Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Induction profile of rat organic anion transporting polypeptide 2 (oatp2) by prototypical drug-metabolizing enzyme inducers that activate gene expression through ligand-activated transcription factor pathways.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole.

Journal: Molecular pharmacology 20020101

Title: Cytochrome P4501A responses in two tropical fish species, riverine catfish (Rita rita) and marine mudfish (Apocryptes bato).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020101

Title: Differences between rats and mice in induction of 4S beta-naphthoflavone-binding protein expression by treatment with beta-naphthoflavone.

Journal: Journal of applied genetics 20020101

Title: In vitro mechanistic differences in benzo[a]pyrene-DNA adduct formation using fish liver and mussel digestive gland microsomal activating systems.

Journal: Marine environmental research 20020101

Title: Induction of DNA strand breakage and apoptosis in the eel Anguilla anguilla.

Journal: Marine environmental research 20020101

Title: The expression of CYP1A, vitellogenin and zona radiata proteins in Atlantic salmon (Salmo salar) after oral dosing with two commercial PBDE flame retardant mixtures: absence of short-term responses.

Journal: Marine environmental research 20020101

Title: Comparison of activities dependent on glutathione S-transferase and cytochrome P-450 IA1 in cultured keratinocytes and reconstructed epidermal models.

Journal: Skin pharmacology and applied skin physiology 20020101

Title: A high-throughput cell-based reporter gene system for measurement of CYP1A1 induction.

Journal: Journal of pharmacological and toxicological methods 20020101

Title: Estrogen-mediated suppression of cytochrome P4501A (CYP1A) expression in rainbow trout hepatocytes: role of estrogen receptor.

Journal: Chemico-biological interactions 20011221

Title: Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers.

Journal: World journal of gastroenterology 20011215

Title: Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20011201

Title: Evidence supporting the interaction of CYP2B4 and CYP1A2 in microsomal preparations.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011201

Title: Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20011201

Title: Hepatic 7-ethoxyresorufin O-deethylase activity in eel (Anguilla anguilla) from the Thames Estuary and comparisons with other United Kingdom Estuaries.

Journal: Marine pollution bulletin 20011201

Title: A systematic gene expression screen of Caenorhabditis elegans cytochrome P450 genes reveals CYP35 as strongly xenobiotic inducible.

Journal: Archives of biochemistry and biophysics 20011115

Title: P-glycoprotein in the catfish intestine: inducibility by xenobiotics and functional properties.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20011112

Title: Regulation of rat carboxylesterase expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): a dose-dependent decrease in mRNA levels but a biphasic change in protein levels and activity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20011101

Title: Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices.

Journal: Journal of pineal research 20011101

Title: An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and beta-naphthoflavone binding.

Journal: Gene 20011031

Title: Stimulatory effects of selected PAHs on testosterone production in goldfish and rainbow trout and possible mechanisms of action.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011001

Title: Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice.

Journal: Chemico-biological interactions 20010928

Title: 7-Ethoxyresorufin O-deethylase induction in rainbow trout gill epithelium cultured on permeable supports: asymmetrical distribution of substrate metabolites.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20010901

Title: Effect of beta-naphthoflavone and dimethylbenz[a]anthracene on apoptosis and HSP70 expression in juvenile channel catfish (Ictalurus punctatus) ovary.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20010901

Title: Cytochrome P450 induction in rat hepatocytes assessed by quantitative real-time reverse-transcription polymerase chain reaction and the RNA invasive cleavage assay.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010901

Title: Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans.

Journal: Molecular endocrinology (Baltimore, Md.) 20010901

Title: Catalytic and immunochemical properties of hepatic cytochrome P450 1A in three avian species treated with beta-naphthoflavone or isosafrole.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010901

Title: Effects of beta-naphthoflavone on the cytochrome P450 system, and phase II enzymes in gilthead seabream (Sparus aurata).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010901

Title: The effect of the arylhydrocarbon receptor on the human steroidogenic acute regulatory gene promoter activity.

Journal: The Journal of steroid biochemistry and molecular biology 20010901

Title: Isolation of regioisomers of N-alkylprotoporphyrin IX from chick embryo liver after treatment with porphyrinogenic xenobiotics.

Journal: Canadian journal of physiology and pharmacology 20010901

Title: Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site.

Journal: Biochemical and biophysical research communications 20010727

Title: Formation of DNA adducts in the aorta of smoke-exposed rats, and modulation by chemopreventive agents.

Journal: Mutation research 20010725

Title: An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene.

Journal: Toxicology and applied pharmacology 20010701

Title: The coronary endothelium-derived hyperpolarizing factor (EDHF) stimulates multiple signalling pathways and proliferation in vascular cells.

Journal: Pflugers Archiv : European journal of physiology 20010701

Title: Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression.

Journal: Life sciences 20010615

Title: Cell-type specific differences in glutamate cysteine ligase transcriptional regulation demonstrate independent subunit control.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010601

Title: Rat cytochrome p450 1A and 3A enzymes involved in bioactivation of tegafur to 5-fluorouracil and autoinduced by tegafur in liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601

Title: Identification of multiple constitutive and inducible hepatic cytochrome P450 enzymes in market weight swine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601

Title: Measurement of cytochrome P4501A induction in dab (Limanda limanda) and other teleosts with species-specific cDNA probes: isolation and characterisation of dab cDNA and its use in expression studies with beta-naphthoflavone-treated fish.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010601

Title: Oxidations of 17beta-estradiol and estrone and their interconversions catalyzed by liver, mammary gland and mammary tumor after acute and chronic treatment of rats with indole-3-carbinol or beta-naphthoflavone.

Journal: Canadian journal of physiology and pharmacology 20010601

Title: Impact of copper on biomonitoring enzyme ethoxyresorufin-o-deethylase in cultured catfish hepatocytes.

Journal: Environmental research 20010601

Title: 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin induces apoptosis in the dorsal midbrain of zebrafish embryos by activation of arylhydrocarbon receptor.

Journal: Neuroscience letters 20010511

Title: Optimization of an exogenous metabolic activation system for FETAX. I. Post-isolation rat liver microsome mixtures.

Journal: Drug and chemical toxicology 20010501

Title: Optimization of an exogenous metabolic activation system for FETAX. II. Preliminary evaluation.

Journal: Drug and chemical toxicology 20010501

Title: Role of cytochrome P450 1A2 in bilirubin degradation Studies in Cyp1a2 (-/-) mutant mice.

Journal: Biochemical pharmacology 20010401

Title: Para-nitrophenol glucuronidation and sulfation in rat and human liver slices.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20010401

Title: Morphology and cytochrome P450 isoforms expression in precision-cut rat liver slices.

Journal: Toxicology 20010321

Title: Monooxygenation, conjugation and other functions in cryopreserved rat liver slices until 24 h after thawing.

Journal: Toxicology 20010321

Title: Modulation of biomarkers by chemopreventive agents in smoke-exposed rats.

Journal: Cancer research 20010315

Title: In vitro biotransformation of xanthohumol, a flavonoid from hops (Humulus lupulus), by rat liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010301

Title: Acquired resistance to Ah receptor agonists in a population of Atlantic killifish (Fundulus heteroclitus) inhabiting a marine superfund site: in vivo and in vitro studies on the inducibility of xenobiotic metabolizing enzymes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010301

Title: Differential sensitivity of rat hepatocyte CYP isoforms to self-generated nitric oxide.

Journal: FEBS letters 20010112

Title: Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes.

Journal: Alternatives to laboratory animals : ATLA 20010101

Title: Pathogenesis of carbon tetrachloride-induced hepatocyte injury bioactivation of CCI4 by cytochrome P450 and effects on lipid homeostasis.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101

Title: Tissue distribution and temperature-dependence of Anguilla anguilla L. EROD activity following exposure to model inducers and relationship with plasma cortisol, lactate and glucose levels.

Journal: Environment international 20010101

Title: Intestinal responses to xenobiotics.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20010101

Title: Baculovirus vectors repress phenobarbital-mediated gene induction and stimulate cytokine expression in primary cultures of rat hepatocytes.

Journal: Gene therapy 20000801

Title: Evidence for cytochrome P4501A2-mediated protein covalent binding of thiabendazole and for its passive intestinal transport: use of human and rabbit derived cells.

Journal: Chemico-biological interactions 20000703

Title: Steroid hormone activity of flavonoids and related compounds.

Journal: Breast cancer research and treatment 20000701

Title: Differential expression of two CYP1A genes in rainbow trout (Oncorhynchys mykiss).

Journal: Toxicology and applied pharmacology 20000615

Title: Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20000601

Title: A novel 4 S [3H]beta-naphthoflavone-binding protein in liver cytosol of female Sprague-Dawley rats treated with aryl hydrocarbon receptor agonists.

Journal: The Biochemical journal 20000501

Title: The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1.

Journal: Archives of biochemistry and biophysics 20000101

Title: Induction of CYP1A by carbofuran in primary culture of fish hepatocytes.

Journal: Journal of biochemical and molecular toxicology 20000101

Title: A human aryl hydrocarbon receptor signaling pathway constructed in yeast displays additive responses to ligand mixtures.

Journal: Toxicology and applied pharmacology 19991101

Title: Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.

Journal: Journal of medicinal chemistry 19991021

Title: Effects of pretreatment with cytochrome P-450 inducers, especially phenobarbital on triphenyltin metabolism and toxicity in hamsters.

Journal: Toxicology 19991001

Title: A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 19990301

Title: Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.

Journal: Cancer research 19990201

Title: Constitutive and induced expression by pyridine and beta-naphthoflavone of rat CYP1A is sexually dimorphic.

Journal: Archives of toxicology 19990101

Title: Prediction of aryl hydrocarbon receptor-mediated enzyme induction of drugs and chemicals by mRNA quantification.

Journal: Chemical research in toxicology 19981201

Title: Increased bioactivation of dihaloalkanes in rat liver due to induction of class theta glutathione S-transferase T1-1.

Journal: The Biochemical journal 19981101

Title: The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic T cell lines.

Journal: The Journal of biological chemistry 19980731

Title: Developmental regulation of the 3-methylcholanthrene- and dioxin-inducible CYP1A5 gene in chick embryo liver in vivo.

Journal: Toxicology and applied pharmacology 19980701

Title: Induction of hepatic cytochrome P-450 by phenobarbital in semi-aquatic frog (Rana pipiens).

Journal: Biochemical and biophysical research communications 19980327

Title: Regulation of sulfotransferase gene expression by glucocorticoid hormones and xenobiotics in primary rat hepatocyte culture.

Journal: Chemico-biological interactions 19980220

Title: Expression of the human aryl hydrocarbon receptor complex in yeast. Activation of transcription by indole compounds.

Journal: The Journal of biological chemistry 19971226

Title: Influence of beta-naphthoflavone and methoxychlor pretreatment on the biotransformation and estrogenic activity of methoxychlor in channel catfish (Ictalurus punctatus).

Journal: Toxicology and applied pharmacology 19970801

Title: Beta-naphthoflavone induced CYP1A1 and 1A3 proteins in the liver of rainbow trout (Oncorhynchus mykiss).

Journal: Xenobiotica; the fate of foreign compounds in biological systems 19970201

Title: Structure and expression of a cluster of glutathione S-transferase genes from a marine fish, the plaice (Pleuronectes platessa).

Journal: The Biochemical journal 19970115

Title: Effects of benzimidazole derivatives on cytochrome P450 1A1 expression in a human hepatoma cell line.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 19970101

Title: Lead nitrate inhibits the induction of CYP1A mRNAs by aromatic amines but not by aryl hydrocarbons in the rat liver.

Journal: Journal of biochemistry 19960901

Title: Induction of CYP1A1 gene by benzimidazole derivatives during Caco-2 cell differentiation. Evidence for an aryl-hydrocarbon receptor-mediated mechanism.

Journal: European journal of biochemistry 19960501

Title: Interactions of flavonoids and other phytochemicals with adenosine receptors.

Journal: Journal of medicinal chemistry 19960202

Title: Glucuronidation in the Caco-2 human intestinal cell line: induction of UDP-glucuronosyltransferase 1*6.

Journal: Biochemical pharmacology 19950808

Title: Induction in vitro and complete coding region sequence of cytochrome P4501A1 cDNA from cultured whole rat conceptuses during early organogenesis.

Journal: Biochemical pharmacology 19941101

Title: 1-Nitronaphthalene toxicity in rat lung and liver: effects of inhibiting and inducing cytochrome P450 activity.

Journal: Toxicology and applied pharmacology 19931001

Title: Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines.

Journal: Carcinogenesis 19930901

Title: NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues.

Journal: Cancer metastasis reviews 19930601

Title: Chemical carcinogens increase IL-1 alpha and IL-6 gene transcripts in human keratinocytes.

Journal: Experimental dermatology 19930301

Title: Inducer-dependent transcriptional activation of the P4501A2 gene in vivo and in isolated hepatocytes.

Journal: The Journal of biological chemistry 19930115

Title: Effects of acute sodium arsenite administration on the pulmonary chemical metabolizing enzymes, cytochrome P-450 monooxygenase, NAD(P)H:quinone acceptor oxidoreductase and glutathione S-transferase in guinea pig: comparison with effects in liver and kidney.

Journal: Chemico-biological interactions 19930101

Title: Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of aldehyde dehydrogenase in hepatoma cells.

Journal: Archives of biochemistry and biophysics 19921101

Title: Induction of CYP1A1 mRNA in rat epidermis and cultured human epidermal keratinocytes by benz(a)anthracene and beta-naphthoflavone.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19920101

Title: Regulation of mouse glutathione S-transferases by chemoprotectors. Molecular evidence for the existence of three distinct alpha-class glutathione S-transferase subunits, Ya1, Ya2, and Ya3, in mouse liver.

Journal: The Biochemical journal 19910601

Title: Expression of two cytochromes P450 involved in carcinogen activation in a human colon cell line.

Journal: Molecular and cellular biochemistry 19910327

Title: Differences in the modulation of P450IA1 and epoxide hydratase expression by benz[a]anthracene and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse embryo versus mouse hepatoma-derived cell lines.

Journal: Carcinogenesis 19901001

Title: Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2.

Journal: Carcinogenesis 19900201

Title: Transcriptional and post-transcriptional regulation of the genes encoding cytochromes P-450c and P-450d in vivo and in primary hepatocyte cultures.

Journal: The Journal of biological chemistry 19880625

Title: The effect of terpenoid compounds on cytochrome P-450 levels in rat liver.

Journal: Biochemical pharmacology 19880601

Title: Uptake and specific binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the olfactory mucosa of mice and rats.

Journal: Cancer research 19870801

Title: Hepatic levels of cytosolic, microsomal and 'mitochondrial' epoxide hydrolases and other drug-metabolizing enzymes after treatment of mice with various xenobiotics and endogenous compounds.

Journal: Chemico-biological interactions 19870101

Title: Correlation between the induction of micronuclei in bone marrow by benzene exposure and the excretion of metabolites in urine of CD-1 mice.

Journal: Toxicology and applied pharmacology 19860930

Title: Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols.

Journal: The Journal of biological chemistry 19860325

Title: The murine aromatic hydrocarbon responsiveness locus: a comparison of receptor levels and several inducible enzyme activities among recombinant inbred lines.

Journal: Journal of biochemical toxicology 19860301

Title: Effects of phenobarbitone and beta-naphthoflavone on hepatic microsomal drug metabolising enzymes of the male beagle dog.

Journal: Biochemical pharmacology 19850901

Title: Enhancing effect of inducers of liver microsomal enzymes on induction of hyperplastic liver nodules by N-2-fluorenylacetamide in rats.

Journal: Journal of the National Cancer Institute 19791201

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Tags:6051-87-2 Molecular Formula|6051-87-2 MDL|6051-87-2 SMILES|6051-87-2 3-phenyl-1H-benzo[f]chromen-1-one