Title: Melatonin attenuates memory impairment induced by Klotho gene deficiency via interactive signaling between MT2 receptor, ERK, and Nrf2-related antioxidant potential.
Journal: The international journal of neuropsychopharmacology 20150401
Title: Anxiolytic effects of the melatonin MT(2) receptor partial agonist UCM765: comparison with melatonin and diazepam.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20121203
Title: Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).
Journal: Journal of pineal research 20121101
Title: Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways.
Journal: Journal of pineal research 20121101
Title: Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle.
Journal: Journal of psychopharmacology (Oxford, England) 20120601
Title: Melatonin ameliorates neural function by promoting endogenous neurogenesis through the MT2 melatonin receptor in ischemic-stroke mice.
Journal: Free radical biology & medicine 20120501
Title: Synthesis and configuration determination of all enantiopure stereoisomers of the melatonin receptor ligand 4-phenyl-2-propionamidotetralin using an expedient optical resolution of 4-phenyl-2-tetralone.
Journal: Organic & biomolecular chemistry 20120114
Title: Melatonin membrane receptor type MT1 modulates cell-mediated immunity in the seasonally breeding tropical rodent Funambulus pennanti.
Journal: Neuroimmunomodulation 20120101
Title: Toward the definition of stereochemical requirements for MT2-selective antagonists and partial agonists by studying 4-phenyl-2-propionamidotetralin derivatives.
Journal: Journal of medicinal chemistry 20111222
Title: Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111214
Title: Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20111001
Title: 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT₂-selective agonists.
Journal: Journal of medicinal chemistry 20110512
Title: Melatonin inhibits tetraethylammonium-sensitive potassium channels of rod ON type bipolar cells via MT2 receptors in rat retina.
Journal: Neuroscience 20110126
Title: MT2 receptors mediate the inhibitory effects of melatonin on nitric oxide-induced relaxation of porcine isolated coronary arteries.
Journal: The Journal of pharmacology and experimental therapeutics 20110101
Title: Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of Gα(s) and Gα(q) proteins.
Journal: Journal of pineal research 20101001
Title: Melatonin decreases cell proliferation and induces melanogenesis in human melanoma SK-MEL-1 cells.
Journal: Journal of pineal research 20100801
Title: Abnormal proliferation and differentiation of osteoblasts from girls with adolescent idiopathic scoliosis to melatonin.
Journal: Journal of pineal research 20100801
Title: Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells.
Journal: The Journal of physiology 20100715
Title: The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor.
Journal: British journal of pharmacology 20091101
Title: Design and synthesis of 3-phenyltetrahydronaphthalenic derivatives as new selective MT2 melatoninergic ligands. Part II.
Journal: Bioorganic & medicinal chemistry 20090415
Title: 2-[(2,3-dihydro-1H-indol-1-yl)methyl]melatonin analogues: a novel class of MT2-selective melatonin receptor antagonists.
Journal: Journal of medicinal chemistry 20090212
Title: Luzindole but not 4-phenyl-2- propionamidotetralin (4P-PDOT) diminishes the inhibitory effect of melatonin on murine Colon 38 cancer growth in vitro.
Journal: Neuro endocrinology letters 20090101
Title: Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance.
Journal: Journal of pineal research 20081101
Title: Melatonin-enhanced hyperactivation of hamster sperm.
Journal: Reproduction (Cambridge, England) 20081101
Title: Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells.
Journal: Journal of pineal research 20081001
Title: Effects of melatonin on blood pressure in stress-induced hypertension in rats.
Journal: Clinical and experimental pharmacology & physiology 20081001
Title: Melatonin receptor agonist ramelteon activates the extracellular signal-regulated kinase 1/2 in mouse cerebellar granule cells.
Journal: Neuroscience 20080909
Title: Expression of melatonin receptor (MT1) and interaction between melatonin and estrogen in endometrial cancer cell line.
Journal: The journal of obstetrics and gynaecology research 20080801
Title: An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT(2) melatonin receptor antagonist.
Journal: Organic & biomolecular chemistry 20080107
Title: Melatonin inhibitory effect on cAMP accumulation in the chick retina development.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080101
Title: Melatonin signaling regulates locomotion behavior and homeostatic states through distinct receptor pathways in Caenorhabditis elegans.
Journal: Neuropharmacology 20070701
Title: Signaling mechanisms of melatonin in antiproliferation of hormone-refractory 22Rv1 human prostate cancer cells: implications for prostate cancer chemoprevention.
Journal: Journal of pineal research 20070301
Title: Chronic hypoxia modulates the function and expression of melatonin receptors in the rat carotid body.
Journal: Journal of pineal research 20060301
Title: Melatonin inhibits hippocampal long-term potentiation.
Journal: The European journal of neuroscience 20051101
Title: Melatonin decreases calcium levels in retinotectal axons of Xenopus laevis by indirect activation of group III metabotropic glutamate receptors.
Journal: Brain research 20050816
Title: Stimulation of melatonin receptors decreases calcium levels in xenopus tectal cells by activating GABA(C) receptors.
Journal: Journal of neurophysiology 20050801
Title: Molecular tools to study melatonin pathways and actions.
Journal: Trends in pharmacological sciences 20050801
Title: Analysis of structure-activity relationships for MT2 selective antagonists by melatonin MT1 and MT2 receptor models.
Journal: Journal of medicinal chemistry 20050616
Title: Melatonin enhances the hypoxic response of rat carotid body chemoreceptor.
Journal: Journal of pineal research 20050401
Title: Hippocampal melatonin receptors modulate seizure threshold.
Journal: Epilepsia 20050401
Title: Intracellular second messengers involved in melatonin signal transduction in chicken splenocytes in vitro.
Journal: Journal of pineal research 20041001
Title: In vivo activation of insulin receptor tyrosine kinase by melatonin in the rat hypothalamus.
Journal: Journal of neurochemistry 20040801
Title: Effects of intrathecal injections of melatonin analogs on capsaicin-induced secondary mechanical allodynia and hyperalgesia in rats.
Journal: Pain 20040601
Title: Melatonin receptor agonist 2-iodomelatonin prevents apoptosis of cerebellar granule neurons via K(+) current inhibition.
Journal: Journal of pineal research 20040301
Title: Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.
Journal: General and comparative endocrinology 20040201
Title: Melatonin attenuates rat carotid chemoreceptor response to hypercapnic acidosis.
Journal: Journal of pineal research 20040101
Title: Melatonin prevents apoptosis and enhances HSP27 mRNA expression induced by heat shock in HL-60 cells: possible involvement of the MT2 receptor.
Journal: Journal of pineal research 20031101
Title: Melatonin slowed the early biochemical progression of hormone-refractory prostate cancer in a patient whose prostate tumor tissue expressed MT1 receptor subtype.
Journal: Journal of pineal research 20031001
Title: Gene expression and functional characterization of melatonin receptors in the spinal cord of the rat: implications for pain modulation.
Journal: Journal of pineal research 20030801
Title: Conformation by NMR of two tetralin-based receptor ligands.
Journal: Farmaco (Societa chimica italiana : 1989) 20030701
Title: New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030601
Title: Melatonin inhibits rat medial vestibular nucleus neuron activity in vitro.
Journal: Neuroscience letters 20030508
Title: Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Journal: Journal of medicinal chemistry 20030410
Title: Short-term exposure to melatonin differentially affects the functional sensitivity and trafficking of the hMT1 and hMT2 melatonin receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20030301
Title: MT(2) melatonin receptors are present and functional in rat caudal artery.
Journal: The Journal of pharmacology and experimental therapeutics 20020901
Title: Receptor-mediated modulation of avian caecal muscle contraction by melatonin: role of tyrosine protein kinase.
Journal: Journal of pineal research 20020401
Title: Constitutively active melatonin MT(1) receptors in male rat caudal arteries.
Journal: European journal of pharmacology 20020329
Title: First cloning and functional characterization of a melatonin receptor in fish brain: a novel one?
Journal: Journal of pineal research 20020301
Title: Dual coupling of MT(1) and MT(2) melatonin receptors to cyclic AMP and phosphoinositide signal transduction cascades and their regulation following melatonin exposure.
Journal: Biochemical pharmacology 20020215
Title: Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge.
Journal: Annals of neurology 20020101
Title: Melatonin receptors in rat hippocampus: molecular and functional investigations.
Journal: Hippocampus 20020101
Title: Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation.
Journal: European journal of pharmacology 20011102
Title: Functional expression of MT2 (Mel1b) melatonin receptors in human PAZ6 adipocytes.
Journal: Endocrinology 20011001
Title: Peripheral melatonin mediates neural stimulation of duodenal mucosal bicarbonate secretion.
Journal: The Journal of clinical investigation 20010815
Title: Expression and functional characterization of the mt1 melatonin receptor from rat brain in Xenopus oocytes: evidence for coupling to the phosphoinositol pathway.
Journal: Journal of pineal research 20010401
Title: Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock.
Journal: American journal of physiology. Cell physiology 20010101
Title: Design of subtype selective melatonin receptor agonists and antagonists.
Journal: Reproduction, nutrition, development 19990101
Title: Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19980901
Title: Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 19970301
