Title: Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20180201

Title: Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion.

Journal: Toxicology and applied pharmacology20180101

Title: Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20171201

Title: Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20171101

Title: Downregulation of UBE2E2 in rat liver cells after hepatocarcinogen treatment facilitates cell proliferation and slowing down of DNA damage response in GST-P-expressing preneoplastic lesions.

Journal: Toxicology and applied pharmacology20171101

Title: Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations.

Journal: Toxicology20170815

Title: Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.

Journal: Toxicology and applied pharmacology20170301

Title: Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis.

Journal: Toxicology and applied pharmacology20160701

Title: Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences.

Journal: The Journal of toxicological sciences20160101

Title: A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.

Journal: Archives of toxicology20151201

Title: Cisplatin-mediated cytotoxicity through inducing CYP4A 11 expression in human renal tubular epithelial cells.

Journal: The Journal of toxicological sciences20151201

Title: Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1).

Journal: Toxicology and applied pharmacology20141001

Title: Effects of clofibric acid alone and in combination with 17β-estradiol on mRNA abundance in primary hepatocytes isolated from rainbow trout.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20140901

Title: Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.

Journal: PloS one20140101

Title: PPARα-mediated responses in human adult liver stem cells: In vivo/in vitro and cross-species comparisons.

Journal: The Journal of steroid biochemistry and molecular biology20131101

Title: SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging.

Journal: Biochemical pharmacology20130501

Title: Synthesis of highly water-soluble fibrate derivatives via BGLation.

Journal: Bioorganic & medicinal chemistry letters20121015

Title: Clofibrate PPARα activation reduces oxidative stress and improves ultrastructure and ventricular hemodynamics in no-flow myocardial ischemia.

Journal: Journal of cardiovascular pharmacology20121001

Title: Changes in lipid content and fatty acid composition along the reproductive cycle of the freshwater mussel Dreissena polymorpha: its modulation by clofibrate exposure.

Journal: The Science of the total environment20120815

Title: Inhibitors of 20-hydroxyeicosatetraenoic acid (20-HETE) formation attenuate the natriuretic effect of dopamine.

Journal: European journal of pharmacology20120705

Title: Novel use of a lipid-lowering fibrate medication to prevent nicotine reward and relapse: preclinical findings.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20120701

Title: Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals20120701

Title: Endothelial nitric oxide synthase impairment is restored by clofibrate treatment in an animal model of hypertension.

Journal: European journal of pharmacology20120615

Title: In vitro antimalarial activity and drug interactions of fenofibric acid.

Journal: Antimicrobial agents and chemotherapy20120601

Title: Clofibrate-induced reduction of plasma branched-chain amino acid concentrations impairs glucose tolerance in rats.

Journal: JPEN. Journal of parenteral and enteral nutrition20120501

Title: Attenuation of kidney injuries maintains serum sulfatide levels dependent on hepatic synthetic ability: a possible involvement of oxidative stress.

Journal: The Tohoku journal of experimental medicine20120501

Title: Sesquiterpene lactones from Tithonia diversifolia act as peroxisome proliferator-activated receptor agonists.

Journal: Bioorganic & medicinal chemistry letters20120415

Title: Biomolecular chemistry of isopropyl fibrates.

Journal: Journal of pharmaceutical sciences20120401

Title: Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.

Journal: Cell biology and toxicology20120401

Title: Regulation of breast cancer resistant protein by peroxisome proliferator-activated receptor α in human brain microvessel endothelial cells.

Journal: Molecular pharmacology20120401

Title: Modulations of cytochrome P450 expression in diabetic mice by berberine.

Journal: Chemico-biological interactions20120305

Title: PPARα is down-regulated following liver transplantation in mice.

Journal: Journal of hepatology20120301

Title: Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20120301

Title: Creativity in art and science: are there two cultures?

Journal: Dialogues in clinical neuroscience20120301

Title: In vivo effects of zearalenone on the expression of proteins involved in the detoxification of rat xenobiotics.

Journal: Environmental toxicology20120201

Title: Single dose of 50 mg/kg clofibrate in jaundice of healthy term neonates: randomised clinical trial of efficacy and safety.

Journal: Indian journal of pediatrics20120201

Title: Inhibitor of growth-4 mediates chromatin modification and has a suppressive effect on tumorigenesis and innate immunity.

Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine20120201

Title: Effect of the topical use of the antioxidant taurine on the two basement membrane proteins of regenerating oral gingival epithelium.

Journal: Journal of periodontology20120101

Title: Promotion of hepatocarcinogenesis by perfluoroalkyl acids in rainbow trout.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20120101

Title: Protective Effects of Peroxisome Proliferator-Activated Receptor-α Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes.

Journal: PPAR research20120101

Title: Nuclear receptors in nonalcoholic Fatty liver disease.

Journal: Journal of lipids20120101

Title: The effect of clofibrate on hyperbilirubinemia of term neonates.

Journal: Acta medica Iranica20120101

Title: Proteomes and signalling pathways of antler stem cells.

Journal: PloS one20120101

Title: Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.

Journal: PloS one20120101

Title: Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics.

Journal: BMC genomics20120101

Title: The use software ERGOSHOW in the education of health and safety at work to regardin the safety to children.

Journal: Work (Reading, Mass.)20120101

Title: Clofibrate for unconjugated hyperbilirubinemia in neonates: a systematic review.

Journal: Indian pediatrics20120101

Title: Serum from calorie-restricted rats activates vascular cell eNOS through enhanced insulin signaling mediated by adiponectin.

Journal: PloS one20120101

Title: Functional Relationships between Lipid Metabolism and Liver Regeneration.

Journal: International journal of hepatology20120101

Title: 5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability.

Journal: Journal of neuroinflammation20120101

Title: The transcriptional response of Caenorhabditis elegans to Ivermectin exposure identifies novel genes involved in the response to reduced food intake.

Journal: PloS one20120101

Title: The Successful Treatment of Chronic Cholecystitis with SpyGlass Cholangioscopy-Assisted Gallbladder Drainage and Irrigation through Self-Expandable Metal Stents.

Journal: Gut and liver20120101

Title: Expression of genes involved in hepatic carnitine synthesis and uptake in dairy cows in the transition period and at different stages of lactation.

Journal: BMC veterinary research20120101

Title: Capture and commercialization of blue land crabs ('guaiamum') Cardisoma guanhumi (Lattreille, 1825) along the coast of Bahia State, Brazil: an ethnoecological approach.

Journal: Journal of ethnobiology and ethnomedicine20120101

Title: The RhoGEF trio functions in sculpting class specific dendrite morphogenesis in Drosophila sensory neurons.

Journal: PloS one20120101

Title: The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes.

Journal: PPAR research20120101

Title: Separation of cis- and trans-Asarone from Acorus tatarinowii by Preparative Gas Chromatography.

Journal: Journal of analytical methods in chemistry20120101

Title: The association of hypertriglyceridemia with cardiovascular events and pancreatitis: a systematic review and meta-analysis.

Journal: BMC endocrine disorders20120101

Title: Estrogen and androgen receptor status in hepatocellular hypertrophy induced by phenobarbital, clofibrate, and piperonyl butoxide in F344 rats.

Journal: The Journal of toxicological sciences20120101

Title: Fenofibrate down-regulates renal OCT2-mediated organic cation transport via PPARα-independent pathways.

Journal: Drug metabolism and pharmacokinetics20120101

Title: Tumor lymphangiogenesis as a potential therapeutic target.

Journal: Journal of oncology20120101

Title: The promoter of Rv0560c is induced by salicylate and structurally-related compounds in Mycobacterium tuberculosis.

Journal: PloS one20120101

Title: Knowledge about epilepsy among health professionals: a cross-sectional survey in Sao Paulo, Brazil.

Journal: BMJ open20120101

Title: Cardiovascular events in patients received combined fibrate/statin treatment versus statin monotherapy: Acute Coronary Syndrome Israeli Surveys data.

Journal: PloS one20120101

Title: A comparative clinical study of hypolipidemic efficacy of Amla (Emblica officinalis) with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitor simvastatin.

Journal: Indian journal of pharmacology20120101

Title: 9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity.

Journal: PloS one20120101

Title: Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.

Journal: Journal of neuroinflammation20120101

Title: A revision and key to the genera of Afrotropical Mantispidae (Neuropterida, Neuroptera), with the description of a new genus.

Journal: ZooKeys20120101

Title: The ascorbate-glutathione-α-tocopherol triad in abiotic stress response.

Journal: International journal of molecular sciences20120101

Title: The genetic structure of Leishmania infantum populations in Brazil and its possible association with the transmission cycle of visceral leishmaniasis.

Journal: PloS one20120101

Title: Opuntia in México: identifying priority areas for conserving biodiversity in a multi-use landscape.

Journal: PloS one20120101

Title: The Relationship between Plants Used to Sustain Finches (Fringillidae) and Uses for Human Medicine in Southeast Spain.

Journal: Evidence-based complementary and alternative medicine : eCAM20120101

Title: AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells.

Journal: PPAR research20120101

Title: Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice.

Journal: PPAR research20120101

Title: A new methodology for vibration error compensation of optical encoders.

Journal: Sensors (Basel, Switzerland)20120101

Title: PPARα Activation Protects against Anti-Thy1 Nephritis by Suppressing Glomerular NF-κB Signaling.

Journal: PPAR research20120101

Title: Organotypic modeling of human keratinocyte response to peroxisome proliferators.

Journal: Cells, tissues, organs20120101

Title: Possible migration and histopathological analysis of injections of polymethylmethacrylate in wistar rats.

Journal: ISRN dermatology20120101

Title: Pan-PPAR Agonist, Bezafibrate, Restores Angiogenesis in Hindlimb Ischemia in Normal and Diabetic Rats.

Journal: International journal of peptides20120101

Title: New systematic assignments in Gonyleptoidea (Arachnida, Opiliones, Laniatores).

Journal: ZooKeys20120101

Title: Removal of pharmaceuticals in biologically treated wastewater by chlorine dioxide or peracetic acid.

Journal: Environmental technology20120101

Title: Tissue-specific differential induction of duplicated fatty acid-binding protein genes by the peroxisome proliferator, clofibrate, in zebrafish (Danio rerio).

Journal: BMC evolutionary biology20120101

Title: Adenovirus-36 is associated with obesity in children and adults in Sweden as determined by rapid ELISA.

Journal: PloS one20120101

Title: Caspase 2 activation and ER stress drive rapid Jurkat cell apoptosis by clofibrate.

Journal: PloS one20120101

Title: Protective role of fibrates in cardiac ischemia/reperfusion.

Journal: Journal of advanced pharmaceutical technology & research20120101

Title: Recollection of the early years of the research on cytochrome P450.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences20111209

Title: Tannic acid is more effective than clofibrate for the elevation of hepatic β-oxidation and the inhibition of 3-hydroxy-3-methyl-glutaryl-CoA reductase and aortic lesion formation in apo E-deficient mice.

Journal: The British journal of nutrition20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology20111201

Title: The Liprin homology domain is essential for the homomeric interaction of SYD-2/Liprin-α protein in presynaptic assembly.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20111109

Title: Severity of coronary artery disease in postmenopausal women: association with the androgen receptor gene (CAG)n repeat polymorphism.

Journal: Menopause (New York, N.Y.)20111101

Title: Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.

Journal: Marine pollution bulletin20111001

Title: Super-induced gene expression of the N-methyl-D-aspartate receptor 2C subunit in chemical-induced hypertrophic liver in rats.

Journal: The Journal of toxicological sciences20111001

Title: Altered expression of GADD45 genes during the development of chemical-mediated liver hypertrophy and liver tumor promotion in rats.

Journal: The Journal of toxicological sciences20111001

Title: Fetal origin of vascular aging.

Journal: Indian journal of endocrinology and metabolism20111001

Title: K2CO3-promoted domino reactions: construction of functionalized 2,3-dihydrobenzofurans and clofibrate analogues.

Journal: The Journal of organic chemistry20110902

Title: Synthesis and biological evaluation of some novel cyclic-imides as hypoglycaemic, anti-hyperlipidemic agents.

Journal: European journal of medicinal chemistry20110901

Title: Randomized trial of immunosuppressive regimens in renal transplantation.

Journal: Journal of the American Society of Nephrology : JASN20110901

Title: PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation.

Journal: Biochimica et biophysica acta20110801

Title: PPARα agonists regulate lipid metabolism and nitric oxide production and prevent placental overgrowth in term placentas from diabetic rats.

Journal: Journal of molecular endocrinology20110801

Title: Endosomal trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia.

Journal: Schizophrenia research20110801

Title: Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy.

Journal: Diabetes & metabolism journal20110801

Title: Regulation mechanism of ABCA1 expression by statins in hepatocytes.

Journal: European journal of pharmacology20110715

Title: Improved neuronal survival of focal ischemia after delipid extracorporeal lipoprotein treatment in hyperlipidemic rabbits.

Journal: Artificial organs20110701

Title: Prevalence of dyslipidemia among Iranian patients with idiopathic tinnitus.

Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences20110701

Title: Physicochemical and biological properties of 2-O-α-D-galactosyl-cyclomaltohexaose (α-cyclodexterin) and -cyclomaltoheptaose (β-cyclodextrin).

Journal: Carbohydrate research20110601

Title: Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.

Journal: European heart journal20110601

Title: Crystal structure of the central coiled-coil domain from human liprin-β2.

Journal: Biochemistry20110510

Title: Pretreatment by low-dose fibrates protects against acute free fatty acid-induced renal tubule toxicity by counteracting PPARα deterioration.

Journal: Toxicology and applied pharmacology20110501

Title: Ablation of PI3K p110-α prevents high-fat diet-induced liver steatosis.

Journal: Diabetes20110501

Title: The impact of VKORC1-1639 G>A polymorphism on the maintenance dose of oral anticoagulants for thromboembolic prophylaxis in North India: A pilot study.

Journal: Indian journal of human genetics20110501

Title: Wild bitter gourd extract up-regulates mRNA expression of PPARα, PPARγ and their target genes in C57BL/6J mice.

Journal: Journal of ethnopharmacology20110426

Title: Decrease of hepatic stellate cells in rats with enhanced sensitivity to clofibrate-induced hepatocarcinogenesis.

Journal: Cancer science20110401

Title: [Examples of results of pharmaceutical cerebrovascular protection, with special emphasis on the statins].

Journal: Ideggyogyaszati szemle20110330

Title: Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells.

Journal: Cancer gene therapy20110301

Title: Nutritional and metabolic status of HIV-positive patients with lipodystrophy during one year of follow-up.

Journal: Clinics (Sao Paulo, Brazil)20110301

Title: Immunobiological properties of selected natural and chemically modified phenylpropanoids.

Journal: Interdisciplinary toxicology20110301

Title: Feedback modeling of non-esterified fatty acids in rats after nicotinic acid infusions.

Journal: Journal of pharmacokinetics and pharmacodynamics20110201

Title: Type 2 diabetes: uses of thiazolidinediones and insulin.

Journal: Diabetes care20110201

Title: A newly identified CG301269 improves lipid and glucose metabolism without body weight gain through activation of peroxisome proliferator-activated receptor alpha and gamma.

Journal: Diabetes20110201

Title: Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages.

Journal: Toxicology letters20110115

Title: 26-Week carcinogenicity study of di-isodecyl phthalate by dietary administration to CB6F1-rasH2 transgenic mice.

Journal: Archives of toxicology20110101

Title: Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I.

Journal: Brain : a journal of neurology20110101

Title: Effects of clofibrate on salt loading-induced hypertension in rats.

Journal: Journal of biomedicine & biotechnology20110101

Title: Activation of the nuclear receptor PPARα regulates lipid metabolism in foetal liver from diabetic rats: implications in diabetes-induced foetal overgrowth.

Journal: Diabetes/metabolism research and reviews20110101

Title: Transforming Growth Factor-β1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome.

Journal: Cardiology research and practice20110101

Title: Memantine effects on liver and adrenal gland of rats exposed to cold stress.

Journal: International archives of medicine20110101

Title: Marine biodiversity in the Atlantic and Pacific coasts of South America: knowledge and gaps.

Journal: PloS one20110101

Title: Correction: memantine effects on liver and adrenal gland of rats exposed to cold stress.

Journal: International archives of medicine20110101

Title: Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease.

Journal: PloS one20110101

Title: Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis.

Journal: BMC immunology20110101

Title: Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech.

Journal: PloS one20110101

Title: Exogenous control of the expression of Group I CD1 molecules competent for presentation of microbial nonpeptide antigens to human T lymphocytes.

Journal: Clinical & developmental immunology20110101

Title: Did changing primary care delivery models change performance? A population based study using health administrative data.

Journal: BMC family practice20110101

Title: Workers dominate male production in the neotropical bumblebee Bombus wilmattae (Hymenoptera: Apidae).

Journal: Frontiers in zoology20110101

Title: The mechanisms by which lipids coordinately regulate the formation of the protein and lipid domains of the stratum corneum: Role of fatty acids, oxysterols, cholesterol sulfate and ceramides as signaling molecules.

Journal: Dermato-endocrinology20110101

Title: Biochemical and functional characterization of the interaction between liprin-α1 and GIT1: implications for the regulation of cell motility.

Journal: PloS one20110101

Title: Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis.

Journal: PloS one20110101

Title: Targeting Nuclear Hormone Receptors: PPARα Agonists as Potential Disease-Modifying Drugs for Rheumatoid Arthritis.

Journal: International journal of rheumatology20110101

Title: Ethnozoology in Brazil: current status and perspectives.

Journal: Journal of ethnobiology and ethnomedicine20110101

Title: Cerebral fat embolism without intracardiac shunt: A novel presentation.

Journal: Journal of emergencies, trauma, and shock20110101

Title: Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey.

Journal: Drug design, development and therapy20110101

Title: A Comparative Study of the Outer Membrane Proteome from an Atypical and a Typical Enteropathogenic Escherichia coli.

Journal: The open microbiology journal20110101

Title: Evaluation of movements of lower limbs in non-professional ballet dancers: hip abduction and flexion.

Journal: Sports medicine, arthroscopy, rehabilitation, therapy & technology : SMARTT20110101

Title: Liprin-α4 is required for nickel induced receptor protein tyrosine phosphatase-leukocyte antigen related receptor F (RPTP-LAR) activity.

Journal: PloS one20110101

Title: Liver-spleen axis, insulin-like growth factor-(IGF)-I axis and fat mass in overweight/obese females.

Journal: Journal of translational medicine20110101

Title: Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery.

Journal: Pharmacology20110101

Title: Management of thromboangiitis obliterans using distraction osteogenesis: A retrospective study.

Journal: Indian journal of orthopaedics20110101

Title: Combined liquid and solid-phase extraction improves quantification of brain estrogen content.

Journal: Frontiers in neuroanatomy20110101

Title: Effects of the Soluble Fiber Complex PolyGlycopleX on Glucose Homeostasis and Body Weight in Young Zucker Diabetic Rats.

Journal: Frontiers in pharmacology20110101

Title: Analysis of VEGF--a regulated gene expression in endothelial cells to identify genes linked to angiogenesis.

Journal: PloS one20110101

Title: Change and aging senescence as an adaptation.

Journal: PloS one20110101

Title: First somatic mutation of E2F1 in a critical DNA binding residue discovered in well-differentiated papillary mesothelioma of the peritoneum.

Journal: Genome biology20110101

Title: Rhabdomyolysis associated with fenofibrate monotherapy in a patient with chronic myelogenous leukemia.

Journal: Case reports in gastroenterology20110101

Title: Evidence for the role of B cells and immunoglobulins in the pathogenesis of multiple sclerosis.

Journal: Neurology research international20110101

Title: Medicinal Chemistry and Actions of Dual and Pan PPAR Modulators.

Journal: The open medicinal chemistry journal20110101

Title: Association between Cystatin C and MRI Measures of Left Ventricular Structure and Function: Multi-Ethnic Study of Atherosclerosis.

Journal: International journal of nephrology20110101

Title: The mechanisms by which polyamines accelerate tumor spread.

Journal: Journal of experimental & clinical cancer research : CR20110101

Title: A new baseline for fascioliasis in Venezuela: lymnaeid vectors ascertained by DNA sequencing and analysis of their relationships with human and animal infection.

Journal: Parasites & vectors20110101

Title: Ayurvedic medicine and anaesthesia.

Journal: Indian journal of anaesthesia20110101

Title: NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA.

Journal: International journal of hepatology20110101

Title: Chest associated to motor physiotherapy improves cardiovascular variables in newborns with respiratory distress syndrome.

Journal: International archives of medicine20110101

Title: The effect of cocoa supplementation on hepatic steatosis, reactive oxygen species and LFABP in a rat model of NASH.

Journal: Comparative hepatology20110101

Title: New short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats.

Journal: Cancer informatics20110101

Title: Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats.

Journal: ISRN pharmacology20110101

Title: A proteomic analysis of the functional effects of fatty acids in NIH 3T3 fibroblasts.

Journal: Lipids in health and disease20110101

Title: Clinical and behavioral factors associated with management outcome in hospitalized patients with diabetic foot ulcer.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy20110101

Title: Redescription of Platygyndes Roewer 1943, a false Gonyleptidae, (Arachnida, Opiliones, Cosmetidae).

Journal: ZooKeys20110101

Title: Peroxisome Proliferator-Activated Receptor-α Activation Decreases Mean Arterial Pressure, Plasma Interleukin-6, and COX-2 While Increasing Renal CYP4A Expression in an Acute Model of DOCA-Salt Hypertension.

Journal: PPAR research20110101

Title: Insulin like growth factor-1 (IGF-1) causes overproduction of IL-8, an angiogenic cytokine and stimulates neovascularization in isoproterenol-induced myocardial infarction in rats.

Journal: International journal of molecular sciences20110101

Title: Effects of conjugated linoleic acid, fish oil and soybean oil on PPARs (α & γ) mRNA expression in broiler chickens and their relation to body fat deposits.

Journal: International journal of molecular sciences20110101

Title: Association of PPARα Intron 7 Polymorphism with Coronary Artery Disease: A Cross-Sectional Study.

Journal: ISRN cardiology20110101

Title: Xanthoma disseminatum in a pair of blind, deaf male twins.

Journal: ISRN dermatology20110101

Title: Building a open source framework for virtual medical training.

Journal: Journal of digital imaging20101201

Title: Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101201

Title: Lipoprotein(a) as a cardiovascular risk factor: current status.

Journal: European heart journal20101201

Title: Regulation of liver fatty acid binding protein expression by clofibrate in hepatoma cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire20101201

Title: Short term effect and safety of antidiuretic hormone in the patients with nocturia.

Journal: International neurourology journal20101201

Title: Response to: Laparoscopic cholecystectomy is safe and effective for the treatment of biliary dyskinesia in the pediatric population.

Journal: The American surgeon20101201

Title: Successful drug development despite adverse preclinical findings part 1: processes to address issues and most important findings.

Journal: Journal of toxicologic pathology20101201

Title: Three Drosophila liprins interact to control synapse formation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20101117

Title: Peroxisome proliferator-activated receptor {alpha} agonism prevents renal damage and the oxidative stress and inflammatory processes affecting the brains of stroke-prone rats.

Journal: The Journal of pharmacology and experimental therapeutics20101101

Title: Stress signaling in the methionine-choline-deficient model of murine fatty liver disease.

Journal: Gastroenterology20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Are there modifiable risk factors which will reduce the excess mortality in schizophrenia?

Journal: Journal of psychopharmacology (Oxford, England)20101101

Title: The Caenorhabditis elegans Kinesin-3 motor UNC-104/KIF1A is degraded upon loss of specific binding to cargo.

Journal: PLoS genetics20101101

Title: Metformin for aging and cancer prevention.

Journal: Aging20101101

Title: Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.

Journal: International journal of environmental research and public health20101101

Title: Liprin-α4 is a new hypoxia-inducible target gene required for maintenance of cell-cell contacts.

Journal: Experimental cell research20101015

Title: Involvement of PPARα and PPARγ in apoptosis and proliferation of human hepatocarcinoma HepG2 cells.

Journal: Cell biochemistry and function20101001

Title: State of the art in muscle lipid diseases.

Journal: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology20101001

Title: Effect of prenatal peroxisome proliferator-activated receptor alpha (PPARalpha) agonism on postnatal development.

Journal: Toxicology20100930

Title: Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.

Journal: Mutation research20100930

Title: Monocarboxylate transporter 1 and CD147 are up-regulated by natural and synthetic peroxisome proliferator-activated receptor alpha agonists in livers of rodents and pigs.

Journal: Molecular nutrition & food research20100901

Title: Interaction of oxazaphosphorines with multidrug resistance-associated protein 4 (MRP4).

Journal: The AAPS journal20100901

Title: Expression of two cytochrome P450 aromatase genes is regulated by endocrine disrupting chemicals in rare minnow Gobiocypris rarus juveniles.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20100901

Title: Antilipidemic adherence post-coronary artery disease diagnosis among those with and without an ICD-9 diagnosis of depression.

Journal: Journal of psychosomatic research20100801

Title: Role of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic mice.

Journal: The pharmacogenomics journal20100601

Title: Multi-residue method for the analysis of pharmaceutical compounds in sewage sludge, compost and sediments by sonication-assisted extraction and LC determination.

Journal: Journal of separation science20100601

Title: Effects of the peroxisome proliferator-activated receptor-alpha agonists clofibrate and fish oil on hepatic fatty acid metabolism in weaned dairy calves.

Journal: Journal of dairy science20100601

Title: Does the blood pressure-lowering effect of statins contribute to their beneficial cardiovascular effects?

Journal: Expert review of cardiovascular therapy20100601

Title: Effect of a Large Dose of Di (2-ethylhexyl) phthalate (DEHP) on Hepatic Peroxisome in Cynomolgus Monkeys (Macaca Fascicularis).

Journal: Journal of toxicologic pathology20100601

Title: A historical perspective on the discovery of statins.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences20100511

Title: Glutathione S-transferase A4 is a positive marker for rat hepatic foci induced by clofibrate and genotoxic carcinogens.

Journal: Cancer science20100501

Title: Evaluation of a liver micronucleus assay in young rats (III): a study using nine hepatotoxicants by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS).

Journal: Mutation research20100430

Title: Synthesis of a novel alpha-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of iNKT cells in the production of antilipid antibodies.

Journal: Bioconjugate chemistry20100421

Title: Validation of an in vitro screening test for predicting the tumor promoting potential of chemicals based on gene expression.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20100401

Title: Liprin-alpha1 affects the distribution of low-affinity beta1 integrins and stabilizes their permanence at the cell surface.

Journal: Experimental cell research20100401

Title: Histone acetylation and steroid receptor coactivator expression during clofibrate-induced rat hepatocarcinogenesis.

Journal: Cancer science20100401

Title: Cholesterol-lowering and cancer in the prevention of cardiovascular disease.

Journal: QJM : monthly journal of the Association of Physicians20100301

Title: The Effect of Clofibrate on Decreasing Serum Bilirubin in Healthy Term Neonates under Home Phototherapy.

Journal: Iranian journal of pediatrics20100301

Title: The role of peroxisome proliferator-activated receptor alpha in transcriptional regulation of novel organic cation transporters.

Journal: European journal of pharmacology20100225

Title: The effect of Telmisartan on collagen biosynthesis depends on the status of estrogen activation in breast cancer cells.

Journal: European journal of pharmacology20100225

Title: PPARalpha stimulation exerts a blood pressure lowering effect through different mechanisms in a time-dependent manner.

Journal: European journal of pharmacology20100210

Title: Proteomics analysis of cardiac muscle from rats with peroxisomal proliferator-activated receptor alpha (PPARalpha) stimulation.

Journal: The Journal of toxicological sciences20100201

Title: Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity.

Journal: Blood20100128

Title: PPFIA1 and CCND1 are frequently coamplified in breast cancer.

Journal: Genes, chromosomes & cancer20100101

Title: Glucans from the Caripia montagnei mushroom present anti-inflammatory activity.

Journal: International immunopharmacology20100101

Title: Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20100101

Title: Cytotoxic properties of clofibrate and other peroxisome proliferators: relevance to cancer progression.

Journal: Current medicinal chemistry20100101

Title: PPARs in Irradiation-Induced Gastrointestinal Toxicity.

Journal: PPAR research20100101

Title: Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).

Journal: BMC genomics20100101

Title: Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes.

Journal: BMC genomics20100101

Title: Mitochondrial HMG-CoA synthase partially contributes to antioxidant protection in the kidney of stroke-prone spontaneously hypertensive rats.

Journal: Nutrition (Burbank, Los Angeles County, Calif.)20100101

Title: Peroxisome proliferator-activated receptor (PPAR): balance for survival in parasitic infections.

Journal: Journal of biomedicine & biotechnology20100101

Title: Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in Jurkat T-cells.

Journal: PloS one20100101

Title: Perturbation of lipids and glucose metabolism associated with previous 2,4-D exposure: a cross-sectional study of NHANES III data, 1988-1994.

Journal: Environmental health : a global access science source20100101

Title: Salt stress causes peroxisome proliferation, but inducing peroxisome proliferation does not improve NaCl tolerance in Arabidopsis thaliana.

Journal: PloS one20100101

Title: Motor neuron synapse and axon defects in a C. elegans alpha-tubulin mutant.

Journal: PloS one20100101

Title: Breast cancer mortality in organised mammography screening in Denmark: comparative study.

Journal: BMJ (Clinical research ed.)20100101

Title: The efficacy of Artecoll injections for the augmentation of nipple projection in breast reconstruction.

Journal: Eplasty20100101

Title: Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp. aurantifolii.

Journal: BMC genomics20100101

Title: PPARalpha: energy combustion, hypolipidemia, inflammation and cancer.

Journal: Nuclear receptor signaling20100101

Title: Critical appraisal of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.

Journal: Therapeutics and clinical risk management20100101

Title: 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice.

Journal: PloS one20100101

Title: Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in mice.

Journal: PloS one20100101

Title: Sequence features involved in the mechanism of 3' splice junction wobbling.

Journal: BMC molecular biology20100101

Title: CFTR depletion results in changes in fatty acid composition and promotes lipogenesis in intestinal Caco 2/15 cells.

Journal: PloS one20100101

Title: Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosis.

Journal: BMC gastroenterology20100101

Title: Brain serotonergic and dopaminergic modulators, perceptual responses and endurance exercise performance following caffeine co-ingested with a high fat meal in trained humans.

Journal: Journal of the International Society of Sports Nutrition20100101

Title: Fenofibric acid: a new fibrate approved for use in combination with statin for the treatment of mixed dyslipidemia.

Journal: Vascular health and risk management20100101

Title: Prevention of cardiovascular disease utilizing fibrates--a pooled meta-analysis.

Journal: American journal of therapeutics20100101

Title: Integrative analysis of DNA copy number and gene expression in metastatic oral squamous cell carcinoma identifies genes associated with poor survival.

Journal: Molecular cancer20100101

Title: Membrane plasmalogen composition and cellular cholesterol regulation: a structure activity study.

Journal: Lipids in health and disease20100101

Title: Regulation of cerebrovascular endothelial peroxisome proliferator activator receptor alpha expression and nitric oxide production by clofibrate.

Journal: Bratislavske lekarske listy20100101

Title: Anti-atherogenic property of ferulic acid in apolipoprotein E-deficient mice fed Western diet: comparison with clofibrate.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20100101

Title: Constraints to virus infection in Nicotiana benthamiana plants transformed with a potyvirus amplicon.

Journal: BMC plant biology20100101

Title: Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors.

Journal: PPAR research20100101

Title: Phylogenetic and morphologic analyses of a coastal fish reveals a marine biogeographic break of terrestrial origin in the southern Caribbean.

Journal: PloS one20100101

Title: Effects of Endogenous PPAR Agonist Nitro-Oleic Acid on Metabolic Syndrome in Obese Zucker Rats.

Journal: PPAR research20100101

Title: Contextual and individual assessment of dental pain period prevalence in adolescents: a multilevel approach.

Journal: BMC oral health20100101

Title: The Role of PPARα Activation in Liver and Muscle.

Journal: PPAR research20100101

Title: PPARα in Obesity: Sex Difference and Estrogen Involvement.

Journal: PPAR research20100101

Title: PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex.

Journal: PPAR research20100101

Title: Role of PPARα in Hepatic Carbohydrate Metabolism.

Journal: PPAR research20100101

Title: Peroxisome proliferator-activated receptor alpha target genes.

Journal: PPAR research20100101

Title: Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism.

Journal: PPAR research20100101

Title: Practical application of toxicogenomics for profiling toxicant-induced biological perturbations.

Journal: International journal of molecular sciences20100101

Title: Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice.

Journal: Lipids in health and disease20100101

Title: Omega-6 fat supplementation alters lipogenic gene expression in bovine subcutaneous adipose tissue.

Journal: Gene regulation and systems biology20100101

Title: Role of PPARα and Its Agonist in Renal Diseases.

Journal: PPAR research20100101

Title: RhoA regulates peroxisome association to microtubules and the actin cytoskeleton.

Journal: PloS one20100101

Title: Niacin or ezetimibe for patients with, or at risk of coronary heart disease.

Journal: Clinical Medicine Insights. Cardiology20100101

Title: Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice.

Journal: PloS one20100101

Title: Steroid receptor coactivator 1 deficiency increases MMTV-neu mediated tumor latency and differentiation specific gene expression, decreases metastasis, and inhibits response to PPAR ligands.

Journal: BMC cancer20100101

Title: Effect of clofibrate on vascular reactivity in a model of high blood pressure secondary to aortic coarctation.

Journal: Pharmacological reports : PR20100101

Title: Low high-density lipoprotein cholesterol: current status and future strategies for management.

Journal: Vascular health and risk management20100101

Title: Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease.

Journal: International journal of Alzheimer's disease20100101

Title: Optimal management of familial hypercholesterolemia: treatment and management strategies.

Journal: Vascular health and risk management20100101

Title: Decreasing the number of false positives in sequence classification.

Journal: BMC genomics20100101

Title: Changes in glucose and glutamine lymphocyte metabolisms induced by type I interferon α.

Journal: Mediators of inflammation20100101

Title: Regulation of Proteome Maintenance Gene Expression by Activators of Peroxisome Proliferator-Activated Receptor α.

Journal: PPAR research20100101

Title: Archaeosome adjuvant overcomes tolerance to tumor-associated melanoma antigens inducing protective CD8 T cell responses.

Journal: Clinical & developmental immunology20100101

Title: A study of standardized extracts of Picrorhiza kurroa Royle ex Benth in experimental nonalcoholic fatty liver disease.

Journal: Journal of Ayurveda and integrative medicine20100101

Title: Interactions of polymorphisms in different clock genes associated with circadian phenotypes in humans.

Journal: Genetics and molecular biology20100101

Title: Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia.

Journal: Drug, healthcare and patient safety20100101

Title: Drug interaction as cause of spontaneously resolving epidural spinal hematoma on warfarin therapy.

Journal: Journal of neurosciences in rural practice20100101

Title: PPARs and xenobiotic-induced adverse effects: relevance to human health.

Journal: PPAR research20100101

Title: Phytoconstituents as photoprotective novel cosmetic formulations.

Journal: Pharmacognosy reviews20100101

Title: A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy.

Journal: Clinical pharmacology : advances and applications20100101

Title: Levelling profiles and a GPS network to monitor the active folding and faulting deformation in the Campo de Dalias (Betic Cordillera, southeastern Spain).

Journal: Sensors (Basel, Switzerland)20100101

Title: Hypocholesterolemia secondary to atrovastatin therapy.

Journal: Journal of Ayub Medical College, Abbottabad : JAMC20100101

Title: Specification of progression in glaucomatous visual field loss, applying locally condensed stimulus arrangements.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie20091201

Title: PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol.

Journal: The Journal of pharmacology and experimental therapeutics20091201

Title: Rhabdomyolysis associated with fibrate therapy: review of 76 published cases and a new case report.

Journal: European journal of clinical pharmacology20091201

Title: Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs.

Journal: The Journal of toxicological sciences20091201

Title: Characteristic upregulation of glucose-regulated protein 78 in an early lesion negative for hitherto established cytochemical markers in rat hepatocarcinogenesis.

Journal: Journal of toxicologic pathology20091201

Title: Bounds on causal effects in randomized trials with noncompliance under monotonicity assumptions about covariates.

Journal: Statistics in medicine20091120

Title: Blastocystis: unravelling potential risk factors and clinical significance of a common but neglected parasite.

Journal: Epidemiology and infection20091101

Title: A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.

Journal: Environmental health perspectives20091101

Title: Regulation of CYP4A expression by bezafibrate in primary culture of rat and human hepatocytes: interspecies difference and influence of N-acetylcysteine.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20091001

Title: The complexity of the relationship between chronic pain and quality of life: a study of the general Norwegian population.

Journal: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation20091001

Title: An induction in hepatic HDL secretion associated with reduced ATPase expression.

Journal: The American journal of pathology20091001

Title: [Advances in the study of regulation of novel organic cation transporter-2].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20091001

Title: Liprin-alpha1 promotes cell spreading on the extracellular matrix by affecting the distribution of activated integrins.

Journal: Journal of cell science20090915

Title: Probing the fibrate binding specificity of rat liver fatty acid binding protein.

Journal: Journal of medicinal chemistry20090910

Title: Docosahexaenoic acid inhibits superoxide dismutase 1 gene transcription in human cancer cells: the involvement of peroxisome proliferator-activated receptor alpha and hypoxia-inducible factor-2alpha signaling.

Journal: Molecular pharmacology20090901

Title: Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner.

Journal: Hepatology (Baltimore, Md.)20090901

Title: Influence of pharmacological PPARalpha activators on carnitine homeostasis in proliferating and non-proliferating species.

Journal: Pharmacological research20090901

Title: The scientific production of full professors of the Faculdade de Medicina da Universidade de São Paulo: a view of the period of 2001-2006.

Journal: Clinics (Sao Paulo, Brazil)20090901

Title: Scoring multiple toxicological endpoints using a toxicogenomic database.

Journal: Toxicology letters20090724

Title: Interventions in the management of serum lipids for preventing stroke recurrence.

Journal: The Cochrane database of systematic reviews20090708

Title: Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis.

Journal: Experimental dermatology20090701

Title: Effects of growth conditions on the barrier properties of a human skin equivalent.

Journal: Pharmaceutical research20090701

Title: The role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor alpha (PPAR-alpha) in the regulation of inflammation in macrophages.

Journal: Shock (Augusta, Ga.)20090701

Title: Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis.

Journal: PLoS genetics20090701

Title: Clinical characteristics of patients with trigeminal neuralgia referred to neurosurgery.

Journal: European journal of dentistry20090701

Title: Lipid determinants of cell death.

Journal: Plant signaling & behavior20090701

Title: Perturbation in kidney lipid metabolic profiles in diabetic rats with reference to alcoholic oxidative stress.

Journal: Indian journal of nephrology20090701

Title: Design, synthesis and hypolipidemic activity of novel 2-(m-tolyloxy) isobutyric acid derivatives.

Journal: European journal of medicinal chemistry20090601

Title: Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy.

Journal: The Journal of toxicological sciences20090601

Title: Human health risk assessment for peroxisome proliferators: more than 30 years of research.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie20090501

Title: In vitro assay for drug-induced hepatosteatosis using rat primary hepatocytes, a fluorescent lipid analog and gene expression analysis.

Journal: Journal of applied toxicology : JAT20090501

Title: Body shaping and volume restoration: the role of hyaluronic acid.

Journal: Aesthetic plastic surgery20090501

Title: PPARalpha signaling mediates the synergistic cytotoxicity of clioquinol and docosahexaenoic acid in human cancer cells.

Journal: Biochemical pharmacology20090501

Title: The effect of clofibrate with phototherapy in late pre-term newborns with non-hemolytic jaundice.

Journal: Indian journal of medical sciences20090501

Title: Statins, stem cells, and cancer.

Journal: Journal of cellular biochemistry20090415

Title: Similar compounds searching system by using the gene expression microarray database.

Journal: Toxicology letters20090410

Title: Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated receptor alpha-independent mechanism.

Journal: Molecular pharmacology20090401

Title: Antidiabetic action of bezafibrate in a large observational database.

Journal: Diabetes care20090401

Title: Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2.

Journal: Drug metabolism and disposition: the biological fate of chemicals20090401

Title: Clinical variables affecting survival in patients with decompensated diastolic versus systolic heart failure.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society20090401

Title: Structure-activity-dependent regulation of cell communication by perfluorinated fatty acids using in vivo and in vitro model systems.

Journal: Environmental health perspectives20090401

Title: Regulation of peroxisome proliferator-activated receptor-alpha by MDM2.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20090301

Title: Glomerular 20-HETE, EETs, and TGF-beta1 in diabetic nephropathy.

Journal: American journal of physiology. Renal physiology20090301

Title: Participation of low molecular weight electron carriers in oxidative protein folding.

Journal: International journal of molecular sciences20090301

Title: Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains.

Journal: Journal of toxicologic pathology20090301

Title: Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification.

Journal: The Journal of investigative dermatology20090201

Title: Common sequence variant in lipoprotein lipase gene conferring triglyceride response to fibrate treatment.

Journal: Pharmacogenomics20090201

Title: Improvement in lipid profile of patients referred to a cardiac rehabilitation program: is the effect of regular exercise underestimated because of the antilipid drugs?

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology20090201

Title: Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment.

Journal: Toxicologic pathology20090201

Title: The effect of dyslipidemic drugs on mortality: A meta-analysis.

Journal: Indian journal of pharmacology20090201

Title: Activation of hepatic lipase expression by oleic acid: possible involvement of USF1.

Journal: Nutrients20090201

Title: Relationship between micronuclei formation and p53 induction.

Journal: Mutation research20090131

Title: Mechanisms of clofibrate-induced apoptosis in Yoshida AH-130 hepatoma cells.

Journal: Biochemical pharmacology20090115

Title: Does nicotinic acid (niacin) lower blood pressure?

Journal: International journal of clinical practice20090101

Title: Rhizobia with different symbiotic efficiencies nodulate Acaciella angustissima in Mexico, including Sinorhizobium chiapanecum sp. nov. which has common symbiotic genes with Sinorhizobium mexicanum.

Journal: FEMS microbiology ecology20090101

Title: Are animal models predictive for humans?

Journal: Philosophy, ethics, and humanities in medicine : PEHM20090101

Title: Fibrates and microvascular complications in diabetes--insight from the FIELD study.

Journal: Current pharmaceutical design20090101

Title: Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis.

Journal: BMJ (Clinical research ed.)20090101

Title: Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis.

Journal: Respiratory research20090101

Title: Systems biology for identifying liver toxicity pathways.

Journal: BMC proceedings20090101

Title: Naming a phantom - the quest to find the identity of Ulluchu, an unidentified ceremonial plant of the Moche culture in Northern Peru.

Journal: Journal of ethnobiology and ethnomedicine20090101

Title: Regulation of adiponectin receptor 2 expression via PPAR-alpha in NIT-1 cells.

Journal: Endocrine journal20090101

Title: Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane.

Journal: PloS one20090101

Title: PPAR and liver injury in HIV-infected patients.

Journal: PPAR research20090101

Title: MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-γ agonist lowers triglyceride independently of PPAR-α activation.

Journal: PPAR research20090101

Title: A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha.

Journal: Molecular brain20090101

Title: Estrogen-dependent regulation of PPAR-gamma signaling on collagen biosynthesis in adenocarcinoma endometrial cells.

Journal: Neoplasma20090101

Title: Regulation of bile acid and cholesterol metabolism by PPARs.

Journal: PPAR research20090101

Title: Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs.

Journal: PPAR research20090101

Title: Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6.

Journal: BMC cell biology20090101

Title: Pharmacological therapies for unconjugated hyperbilirubinemia.

Journal: Current pharmaceutical design20090101

Title: Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease.

Journal: PPAR research20090101

Title: Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.

Journal: PloS one20090101

Title: Impact of biospecimens handling on biomarker research in breast cancer.

Journal: BMC cancer20090101

Title: Crop and non-crop productivity in a traditional maize agroecosystem of the highland of Mexico.

Journal: Journal of ethnobiology and ethnomedicine20090101

Title: Discrimination of carcinogens by hepatic transcript profiling in rats following 28-day administration.

Journal: Cancer informatics20090101

Title: Fasting Upregulates PPARalpha Target Genes in Brain and Influences Pituitary Hormone Expression in a PPARalpha Dependent Manner.

Journal: PPAR research20090101

Title: Review of extended-release niacin/laropiprant fixed combination in the treatment of mixed dyslipidemia and primary hypercholesterolemia.

Journal: Vascular health and risk management20090101

Title: Madrid hospitals and welfare in the context of the Hapsburg Empire.

Journal: Medical history. Supplement20090101

Title: Review of soft tissue augmentation in the face.

Journal: Clinical, cosmetic and investigational dermatology20090101

Title: Patterns of genetic diversity in southern and southeastern Araucaria angustifolia (Bert.) O. Kuntze relict populations.

Journal: Genetics and molecular biology20090101

Title: A straightforward multiallelic significance test for the Hardy-Weinberg equilibrium law.

Journal: Genetics and molecular biology20090101

Title: Manifestation of renal disease in obesity: pathophysiology of obesity-related dysfunction of the kidney.

Journal: International journal of nephrology and renovascular disease20090101

Title: Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.

Journal: Archives of toxicology20081201

Title: Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model.

Journal: Aging cell20081201

Title: Induction of hepatic glutathione S-transferases in male mice by prototypes of various classes of microsomal enzyme inducers.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20081201

Title: Hormone disruption by PBDEs in adult male sport fish consumers.

Journal: Environmental health perspectives20081201

Title: High glucose conditions induce upregulation of fractalkine and monocyte chemotactic protein-1 in human smooth muscle cells.

Journal: Thrombosis and haemostasis20081201

Title: Hyaluronic acid gel (Juvéderm) preparations in the treatment of facial wrinkles and folds.

Journal: Clinical interventions in aging20081201

Title: Profiling synaptic proteins identifies regulators of insulin secretion and lifespan.

Journal: PLoS genetics20081101

Title: [Effect of clofibrate on myocardial triglyceride accumulation in female obese Zucker rats].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20081101

Title: Behaviour and biomarkers of oxidative stress in Gambusia holbrooki after acute exposure to widely used pharmaceuticals and a detergent.

Journal: Ecotoxicology and environmental safety20081001

Title: Changes in triglyceride levels over time and risk of type 2 diabetes in young men.

Journal: Diabetes care20081001

Title: Colfibrate attenuates blood pressure and sodium retention in DOCA-salt hypertension.

Journal: Kidney international20081001

Title: Effects of peroxisome proliferator-activated receptor alpha (PPARalpha) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells.

Journal: Biochimica et biophysica acta20081001

Title: A novel high-throughput screening assay for putative antidiabetic agents through PPARalpha interactions.

Journal: Journal of biomolecular screening20081001

Title: Maintenance of improved lipid levels following attendance at a cardiovascular risk reduction clinic: a 10-year experience.

Journal: Vascular health and risk management20081001

Title: Selective determination of acidic pharmaceuticals in wastewater using molecularly imprinted solid-phase extraction.

Journal: Analytica chimica acta20080926

Title: Long-term effects of resveratrol supplementation on suppression of atherogenic lesion formation and cholesterol synthesis in apo E-deficient mice.

Journal: Biochemical and biophysical research communications20080912

Title: The role of cytochrome p-450 in salt-sensitive stroke in stroke-prone spontaneously hypertensive rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension20080901

Title: Peroxisome proliferation in Arabidopsis: The challenging identification of ligand perception and downstream signaling is closer.

Journal: Plant signaling & behavior20080901

Title: A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats.

Journal: Toxicology20080819

Title: Effects of fibrates, anti-inflammatory drugs and antidepressants in the fish hepatoma cell line PLHC-1: cytotoxicity and interactions with cytochrome P450 1A.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20080801

Title: Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARalpha with clofibrate.

Journal: Toxicology and applied pharmacology20080801

Title: Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit.

Journal: Cardiovascular drugs and therapy20080801

Title: Toxicokintic and toxicodynamic analysis of clofibrate based on free drug concentrations in nagase analbuminemia rats (NAR).

Journal: The Journal of toxicological sciences20080801

Title: Changes in lipid profile of patients referred to a cardiac rehabilitation program.

Title: Genomic profiling reveals an alternate mechanism for hepatic tumor promotion by perfluorooctanoic acid in rainbow trout.

Journal: Environmental health perspectives20080801

Title: Characterization of the drug binding specificity of rat liver fatty acid binding protein.

Journal: Journal of medicinal chemistry20080710

Title: Peroxisome proliferator-activated receptor alpha activation regulates lipid metabolism in the feto-placental unit from diabetic rats.

Journal: Reproduction (Cambridge, England)20080701

Title: Treatment with pharmacological peroxisome proliferator-activated receptor alpha agonist clofibrate increases intestinal carnitine absorption in rats.

Journal: Pharmacological research20080701

Title: Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems.

Journal: The Journal of biological chemistry20080620

Title: NK T cells provide lipid antigen-specific cognate help for B cells.

Journal: Proceedings of the National Academy of Sciences of the United States of America20080617

Title: Lipid-lowering drug use in Italian primary care: effects of reimbursement criteria revision.

Journal: European journal of clinical pharmacology20080601

Title: Monocarboxylate transporter (MCT)-1 is up-regulated by PPARalpha.

Journal: Biochimica et biophysica acta20080601

Title: Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high-sucrose (cafeteria) diet.

Journal: European journal of nutrition20080601

Title: Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical.

Journal: The AAPS journal20080601

Title: Clofibrate and gemfibrozil induce an embryonic malabsorption syndrome in zebrafish.

Journal: Toxicology and applied pharmacology20080501

Title: Efficacy of clofibrate on severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency (a randomized clinical trial).

Journal: The Southeast Asian journal of tropical medicine and public health20080501

Title: Randomized phase III trial comparing bexarotene (L1069-49)/cisplatin/vinorelbine with cisplatin/vinorelbine in chemotherapy-naive patients with advanced or metastatic non-small-cell lung cancer: SPIRIT I.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20080410

Title: Dietary clofibrate stimulates the formation and size of estradiol-induced breast tumors in female August-Copenhagen Irish (ACI) rats.

Journal: Toxicology20080403

Title: Peroxisome proliferation, wound-activated responses and expression of peroxisome-associated genes are cross-regulated but uncoupled in Arabidopsis thaliana.

Journal: Plant, cell & environment20080401

Title: Practical recommendations for measuring rates of visual field change in glaucoma.

Journal: The British journal of ophthalmology20080401

Title: Genomic structure and regulation of the rat hepatic CYP4F1 gene by peroxisome proliferators.

Journal: Archives of biochemistry and biophysics20080401

Title: The peroxisome: still a mysterious organelle.

Journal: Histochemistry and cell biology20080401

Title: The associations of total and differential white blood cell counts with obesity, hypertension, dyslipidemia and glucose intolerance in a Korean population.

Journal: Journal of Korean medical science20080401

Title: Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 2. Molecular characterization, expression level, and transcriptional activation of peroxisome proliferator-activated receptor alpha.

Journal: Environmental science & technology20080401

Title: Conivaptan: a step forward in the treatment of hyponatremia?

Journal: Therapeutics and clinical risk management20080401

Title: Clofibrate treatment up-regulates novel organic cation transporter (OCTN)-2 in tissues of pigs as a model of non-proliferating species.

Journal: European journal of pharmacology20080331

Title: Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11beta-hydroxysteroid dehydrogenase type 1) gene.

Journal: Molecular and cellular endocrinology20080326

Title: Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor alpha by dehydroepiandrosterone and other peroxisome proliferators.

Journal: Molecular pharmacology20080301

Title: Stereospecific synthesis and bio-activity of novel beta(3)-adrenoceptor agonists and inverse agonists.

Journal: Bioorganic & medicinal chemistry20080301

Title: Clofibrate prevents and reverses the hemodynamic manifestations of hyperthyroidism in rats.

Journal: American journal of hypertension20080301

Title: In vitro gene expression analysis of hepatotoxic drugs in rat primary hepatocytes.

Journal: Journal of applied toxicology : JAT20080301

Title: Peroxisome proliferator-activated receptor alpha activation attenuated angiotensin type 1-mediated but enhanced angiotensin type 2-mediated hemodynamic effects to angiotensin II in the rat.

Journal: Journal of hypertension20080301

Title: Expression of hepatic UDP-glucuronosyltransferase 1A1 and 1A6 correlated with increased expression of the nuclear constitutive androstane receptor and peroxisome proliferator-activated receptor alpha in male rats fed a high-fat and high-sucrose diet.

Journal: Drug metabolism and disposition: the biological fate of chemicals20080201

Title: Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids.

Journal: Molecular pharmacology20080201

Title: Anti-inflammatory actions of perfluorooctanoic acid and peroxisome proliferator-activated receptors (PPAR) alpha and gamma in experimental acute pancreatitis.

Journal: International immunopharmacology20080201

Title: PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice.

Journal: The Journal of clinical investigation20080201

Title: Synthesis of polymeric thiazolidinedione and fibrate conjugates.

Journal: Archives of pharmacal research20080201

Title: Update on the use of fibrates: focus on bezafibrate.

Journal: Vascular health and risk management20080201

Title: Is there a role for fibrates in the management of dyslipidemia in the metabolic syndrome?

Journal: Arteriosclerosis, thrombosis, and vascular biology20080101

Title: Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor alpha in transgenic mice: implications for HCV-associated hepatocarcinogenesis.

Journal: International journal of cancer20080101

Title: Differential effects of long-chain fatty acids and clofibrate on gene expression profiles in cardiomyocytes.

Journal: Archives of Iranian medicine20080101

Title: Peroxisome proliferator activated receptors and lipoprotein metabolism.

Journal: PPAR research20080101

Title: PPAR Agonists and Cardiovascular Disease in Diabetes.

Journal: PPAR research20080101

Title: Should We Use PPAR Agonists to Reduce Cardiovascular Risk?

Journal: PPAR research20080101

Title: Fasting and caloric restriction increases mRNA concentrations of novel organic cation transporter-2 and carnitine concentrations in rat tissues.

Journal: Annals of nutrition & metabolism20080101

Title: Chronic clofibrate administration prevents saline-induced endothelial dysfunction and oxidative stress in young Sprague-Dawley rats.

Journal: Clinical and investigative medicine. Medecine clinique et experimentale20080101

Title: PPAR-alpha Ligands as Potential Therapeutic Agents for Wet Age-Related Macular Degeneration.

Journal: PPAR research20080101

Title: PPARs and Female Reproduction: Evidence from Genetically Manipulated Mice.

Journal: PPAR research20080101

Title: PPAR Ligands for Cancer Chemoprevention.

Journal: PPAR research20080101

Title: PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression.

Journal: BMC genomics20080101

Title: Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis.

Journal: PPAR research20080101

Title: Sensitivity of International Classification of Diseases codes for hyponatremia among commercially insured outpatients in the United States.

Journal: BMC nephrology20080101

Title: Statin induced myopathy and myalgia: time trend analysis and comparison of risk associated with statin class from 1991-2006.

Journal: PloS one20080101

Title: The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products.

Journal: PPAR research20080101

Title: Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?

Journal: PPAR research20080101

Title: PPAR Ligands as Potential Modifiers of Breast Carcinoma Outcomes.

Journal: PPAR research20080101

Title: Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.

Journal: PPAR research20080101

Title: PPAR Regulation of Inflammatory Signaling in CNS Diseases.

Journal: PPAR research20080101

Title: Conjugated linoleic acid modulation of risk factors associated with atherosclerosis.

Journal: Nutrition & metabolism20080101

Title: PPARalpha Ligands as Antitumorigenic and Antiangiogenic Agents.

Journal: PPAR research20080101

Title: Peroxisome proliferator-activated receptors in the modulation of the immune/inflammatory response in atherosclerosis.

Journal: PPAR research20080101

Title: Interspecies data mining to predict novel ING-protein interactions in human.

Journal: BMC genomics20080101

Title: A chemical-genetic strategy reveals distinct temporal requirements for SAD-1 kinase in neuronal polarization and synapse formation.

Journal: Neural development20080101

Title: Cross-Species Differential Plasma Protein Binding of MBX-102/JNJ39659100: A Novel PPAR-gamma Agonist.

Journal: PPAR research20080101

Title: Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation.

Journal: Journal of the International Society of Sports Nutrition20080101

Title: Temporal evaluation of CYP mRNA in mice administered with prototypical P450 inducers: comparison with conventional protein/enzyme methods.

Journal: Drug and chemical toxicology20080101

Title: Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis.

Journal: BMC genomics20080101

Title: Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians.

Journal: Environmental health : a global access science source20080101

Title: PPARalpha/gamma-Independent Effects of PPARalpha/gamma Ligands on Cysteinyl Leukotriene Production in Mast Cells.

Journal: PPAR research20080101

Title: The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression.

Journal: Lipids in health and disease20080101

Title: ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells.

Journal: Molecular cancer20080101

Title: Regulation of peroxisome proliferator-activated receptors by e6-associated protein.

Journal: PPAR research20080101

Title: Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARalpha + gamma Agonists.

Journal: PPAR research20080101

Title: The Role of NF-kappaB in PPARalpha-Mediated Hepatocarcinogenesis.

Journal: PPAR research20080101

Title: Peroxisome proliferator-activated receptors in diabetic nephropathy.

Journal: PPAR research20080101

Title: Two- and three-dimensional quantitative structure-activity relationships studies on a series of liver x receptor ligands.

Journal: The open medicinal chemistry journal20080101

Title: Neuroprotective effects of garlic a review.

Journal: The Libyan journal of medicine20080101

Title: Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liver.

Journal: The Journal of biological chemistry20071214

Title: The myocardial infarct size-limiting and antiarrhythmic effects of acyl-CoA:cholesterol acyltransferase inhibitor VULM 1457 protect the hearts of diabetic-hypercholesterolaemic rats against ischaemia/reperfusion injury both in vitro and in vivo.

Journal: European journal of pharmacology20071208

Title: In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P450 inducers.

Journal: Molecular pharmacology20071201

Title: Fenofibrate inhibits intestinal Cl- secretion by blocking basolateral KCNQ1 K+ channels.

Journal: American journal of physiology. Gastrointestinal and liver physiology20071201

Title: Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity.

Journal: The FEBS journal20071201

Title: Five-year safety and efficacy of a novel polymethylmethacrylate aesthetic soft tissue filler for the correction of nasolabial folds.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]20071201

Title: Prediction of the metabolic interaction of nateglinide with other drugs based on in vitro studies.

Journal: Drug metabolism and pharmacokinetics20071201

Title: Secular trends in lipid-lowering treatment and lipid levels after a first acute myocardial infarction.

Journal: Vascular health and risk management20071201

Title: Effect of VULM 1457, an ACAT inhibitor, on serum lipid levels and on real time red blood cell flow in diabetic and non-diabetic hamsters fed high cholesterol-lipid diet.

Journal: General physiology and biophysics20071201

Title: Treatment of non-alcoholic fatty liver disease.

Journal: Therapeutics and clinical risk management20071201

Title: Dietary oxidised fat up regulates the expression of organic cation transporters in liver and small intestine and alters carnitine concentrations in liver, muscle and plasma of rats.

Journal: The British journal of nutrition20071101

Title: Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL.

Journal: Journal of lipid research20071101

Title: Liprin-alpha proteins: scaffold molecules for synapse maturation.

Journal: Biochemical Society transactions20071101

Title: The role of fibrates in the prevention of cardiovascular disease--a pooled meta-analysis of long-term randomized placebo-controlled clinical trials.

Journal: American heart journal20071101

Title: Effect of clofibrate in non-hemolytic indirect hyperbiliru-binemia in full term neonates.

Journal: Indian journal of pediatrics20071101

Title: Increase of calnexin gene dosage boosts the secretion of heterologous proteins by Hansenula polymorpha.

Journal: FEMS yeast research20071001

Title: Importance of hepatic induction of constitutive androstane receptor and other transcription factors that regulate xenobiotic metabolism and transport.

Journal: Drug metabolism and disposition: the biological fate of chemicals20071001

Title: Comparison of mode of action of four hepatocarcinogens: a model-based approach.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20071001

Title: In situ management and domestication of plants in Mesoamerica.

Journal: Annals of botany20071001

Title: Gene expression profiling of rat liver treated with serum triglyceride-decreasing compounds.

Journal: The Journal of toxicological sciences20071001

Title: Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration.

Journal: Toxicology and applied pharmacology20070915

Title: Cytotoxicity of peroxisome proliferator-activated receptor alpha and gamma agonists in renal proximal tubular cell lines.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20070901

Title: Acute hepatotoxicity: a predictive model based on focused illumina microarrays.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20070901

Title: Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts.

Journal: Clinical and experimental pharmacology & physiology20070901

Title: Perioperative use of cardiac medical therapy among patients undergoing coronary artery bypass graft surgery: a systematic review.

Journal: American heart journal20070901

Title: Clofibrate and dalargin increase luminol-dependent chemiluminescence of mouse blood.

Journal: Bulletin of experimental biology and medicine20070901

Title: Preliminary studies into the effects of the human pharmaceutical Clofibric acid on sperm parameters in adult Fathead minnow.

Journal: Aquatic toxicology (Amsterdam, Netherlands)20070815

Title: Treatment with pharmacological peroxisome proliferator-activated receptor alpha agonist clofibrate causes upregulation of organic cation transporter 2 in liver and small intestine of rats.

Journal: Pharmacological research20070801

Title: Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.

Journal: Toxicology and applied pharmacology20070715

Title: Mitochondria, ciglitazone and liver: a neglected interaction in biochemical pharmacology.

Journal: European journal of pharmacology20070712

Title: Clofibrate causes an upregulation of PPAR-{alpha} target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20070701

Title: Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-beta production.

Journal: Molecular pharmacology20070701

Title: Does the capacity for energy utilization affect the survival of post-smolt Atlantic salmon, Salmo salar L., during natural outbreaks of infectious pancreatic necrosis?

Journal: Journal of fish diseases20070701

Title: Effect of clofibrate in jaundiced full-term infants:a randomized clinical trial.

Journal: Archives of Iranian medicine20070701

Title: [Effects of peroxisome proliferators activated receptors on caveolin-1 expression in foam cells].

Journal: Zhonghua xin xue guan bing za zhi20070701

Title: Quantification and regulation of the subcellular distribution of bile acid coenzyme A:amino acid N-acyltransferase activity in rat liver.

Journal: Journal of lipid research20070601

Title: Analytical development for analysis of pharmaceuticals in water samples by SPE and GC-MS.

Journal: Analytical and bioanalytical chemistry20070601

Title: Effects of clofibrate treatment in laying hens.

Journal: Poultry science20070601

Title: Skeletal muscle susceptibility to clofibrate induction of lesions in rats.

Journal: Toxicologic pathology20070601

Title: Inhibitory effect of PPAR on the expression of EMMPRIN in macrophages and foam cells.

Journal: International journal of cardiology20070502

Title: Ligands of peroxisome proliferator-activated receptor inhibit homocysteine-induced DNA methylation of inducible nitric oxide synthase gene.

Journal: Acta biochimica et biophysica Sinica20070501

Title: The Anti-Obesity Effect of the Palatinose-Based Formula Inslow is Likely due to an Increase in the Hepatic PPAR-alpha and Adipocyte PPAR-gamma Gene Expressions.

Journal: Journal of clinical biochemistry and nutrition20070501

Title: Defect in fatty acid esterification of dolichol in Niemann-Pick type C1 mouse livers in vivo.

Journal: Biochimica et biophysica acta20070401

Title: Expression and antioxidant function of liver fatty acid binding protein in normal and bile-duct ligated rats.

Journal: European journal of pharmacology20070329

Title: Immunoselection and characterization of a human genomic PPAR binding fragment located within POTE genes.

Journal: Biochimie20070301

Title: Fibrates: what have we learned in the past 40 years?

Journal: Pharmacotherapy20070301

Title: Activation of PPARalpha lowers synthesis and concentration of cholesterol by reduction of nuclear SREBP-2.

Journal: Biochemical pharmacology20070215

Title: Role of NAD(P)H:quinone oxidoreductase 1 in clofibrate-mediated hepatoprotection from acetaminophen.

Journal: Toxicology20070212

Title: peroxisome proliferator-activated receptor alpha activation-mediated regulation of endothelin-1 production via nitric oxide and protein kinase C signaling pathways in piglet cerebral microvascular endothelial cell culture.

Journal: The Journal of pharmacology and experimental therapeutics20070201

Title: Primary culture of rat hepatocytes in 96-well plates: effects of extracellular matrix configuration on cytochrome P450 enzyme activity and inducibility, and its application in in vitro cytotoxicity screening.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20070201

Title: A 10-year follow-up of ischemic heart disease risk factors in military pilots.

Journal: Military medicine20070201

Title: Role of cytosolic liver fatty acid binding protein in hepatocellular oxidative stress: effect of dexamethasone and clofibrate treatment.

Journal: Molecular and cellular biochemistry20070101

Title: In silico prediction of pregnane X receptor activators by machine learning approaches.

Journal: Molecular pharmacology20070101

Title: A light- and electron-microscope study of hepatocytes of rats fed different diets.

Journal: Comptes rendus biologies20070101

Title: Ethnobotany in the Cumbres de Monterrey National Park, Nuevo León, México.

Journal: Journal of ethnobiology and ethnomedicine20070101

Title: Whales, dolphins or fishes? The ethnotaxonomy of cetaceans in São Sebastião, Brazil.

Journal: Journal of ethnobiology and ethnomedicine20070101

Title: PPARalpha deficiency in inflammatory cells suppresses tumor growth.

Journal: PloS one20070101

Title: Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients.

Journal: Lipids in health and disease20070101

Title: Feeding oxidized fat during pregnancy up-regulates expression of PPARalpha-responsive genes in the liver of rat fetuses.

Journal: Lipids in health and disease20070101

Title: PPARs in the Control of Uncoupling Proteins Gene Expression.

Journal: PPAR research20070101

Title: Involvement of PPARs in Cell Proliferation and Apoptosis in Human Colon Cancer Specimens and in Normal and Cancer Cell Lines.

Journal: PPAR research20070101

Title: Clofibrate treatment in pigs: effects on parameters critical with respect to peroxisome proliferator-induced hepatocarcinogenesis in rodents.

Journal: BMC pharmacology20070101

Title: The evolutionary conservation of the core components necessary for the extrinsic apoptotic signaling pathway, in Medaka fish.

Journal: BMC genomics20070101

Title: A Three Stage Integrative Pathway Search (TIPS) framework to identify toxicity relevant genes and pathways.

Journal: BMC bioinformatics20070101

Title: Presence of thiamine pyrophosphate in mammalian peroxisomes.

Journal: BMC biochemistry20070101

Title: Clinical experience with polymethylmethacrylate microspheres (Artecoll) for soft-tissue augmentation: a retrospective review.

Journal: Archives of facial plastic surgery20070101

Title: Effect of clofibrate on the enzymes associated with oxidative stress in Wistar rat liver.

Journal: Bratislavske lekarske listy20070101

Title: Peroxisome proliferator-activated receptors and acute lung injury.

Journal: PPAR research20070101

Title: Theoretical investigation of halogen-oxygen bonding and its implications in halogen chemistry and reactivity.

Journal: Bioinorganic chemistry and applications20070101

Title: Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers.

Journal: Breast cancer research : BCR20070101

Title: Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells.

Journal: BMC genomics20070101

Title: Peroxisome proliferator activated receptor ligands as regulators of airway inflammation and remodelling in chronic lung disease.

Journal: PPAR research20070101

Title: Peroxisome proliferators-activated alpha agonist treatment ameliorates hepatic damage in rats with obstructive jaundice: an experimental study.

Journal: BMC gastroenterology20070101

Title: Low-cholesterol diet and antilipid therapy in managing tinnitus and hearing loss in patients with noise-induced hearing loss and hyperlipidemia.

Journal: The international tinnitus journal20070101

Title: Activating effect of benzbromarone, a uricosuric drug, on peroxisome proliferator-activated receptors.

Journal: PPAR research20070101

Title: Peroxisome proliferator-activated receptors in lung cancer.

Journal: PPAR research20070101

Title: Cannabinoids: a new group of agonists of PPARs.

Journal: PPAR research20070101

Title: Phthalate-Induced Liver Protection against Deleterious Effects of the Th1 Response: A Potentially Serious Health Hazard.

Journal: PPAR research20070101

Title: Hypertriglyceridemia and Recurrent Pancreatitis following Splenectomy.

Journal: Case reports in gastroenterology20070101

Title: Utilization of a one-dimensional score for surveying chemical-induced changes in expression levels of multiple biomarker gene sets using a large-scale toxicogenomics database.

Journal: The Journal of toxicological sciences20061201

Title: Profiling of gene expression in rat liver and rat primary cultured hepatocytes treated with peroxisome proliferators.

Journal: The Journal of toxicological sciences20061201

Title: PPARalpha agonists up-regulate organic cation transporters in rat liver cells.

Journal: Biochemical and biophysical research communications20061124

Title: Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility.

Journal: The Journal of biological chemistry20061110

Title: Clofibrate increases hepatic triiodothyronine (T3)- and thyroxine (T4)-glucuronosyltransferase activities and lowers plasma T3 and T4 concentrations in pigs.

Journal: Drug metabolism and disposition: the biological fate of chemicals20061101

Title: Clofibrate acutely reverses saline-induced endothelial dysfunction: role of calcium-activated potassium channels.

Journal: American journal of hypertension20061101

Title: Inability to upregulate cytochrome P450 4A and 2C causes salt sensitivity in young Sprague-Dawley rats.

Journal: American journal of hypertension20061101

Title: Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.

Journal: Journal of the National Cancer Institute20061101

Title: Basic and applied research on domestic, exotic and endangered carnivores. Proceedings of the 5th International Symposium on Canine and Feline Reproduction. August 4-6, 2004. Embu das Artes, Brazil.

Journal: Theriogenology20061001

Title: Role of PPAR-gamma on the pathogenesis and vascular changes in glycerol-induced acute renal failure.

Journal: Pharmacological research20060901

Title: A metabonomics study of the hepatotoxicants galactosamine, methylene dianiline and clofibrate in rats.

Journal: Basic & clinical pharmacology & toxicology20060901

Title: Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.

Journal: Environmental health perspectives20060901

Title: Protective effect of simvastatin and VULM 1457 in ischaemic-reperfused myocardium of the diabetic-hypercholesterolemic rats.

Journal: Die Pharmazie20060901

Title: The interference of pharmaceuticals with endogenous and xenobiotic metabolizing enzymes in carp liver: an in-vitro study.

Journal: Environmental science & technology20060815

Title: SFTG international collaborative study on in vitro micronucleus test II. Using human lymphocytes.

Journal: Mutation research20060804

Title: SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells.

Journal: Mutation research20060804

Title: SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study.

Journal: Mutation research20060804

Title: Agonists of the peroxisome proliferator-activated receptor alpha induce a fiber-type-selective transcriptional response in rat skeletal muscle.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20060801

Title: CYP4 isoform specificity in the omega-hydroxylation of phytanic acid, a potential route to elimination of the causative agent of Refsum's disease.

Journal: The Journal of pharmacology and experimental therapeutics20060801

Title: Expression of a peroxisome proliferator-activated receptor gene (xPPARalpha) from Xenopus laevis in tobacco (Nicotiana tabacum) plants.

Journal: Planta20060801

Title: Different susceptibility to peroxisome proliferator-induced hepatocarcinogenesis in rats with polymorphic glutathione transferase genes.

Journal: Cancer science20060801

Title: Oxidative stress in experimental liver microvesicular steatosis: role of mitochondria and peroxisomes.

Journal: Journal of gastroenterology and hepatology20060801

Title: Use of cardiovascular medical therapy among patients undergoing coronary artery bypass graft surgery: results from the ROSETTA-CABG registry.

Journal: The Canadian journal of cardiology20060801

Title: Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver.

Journal: Life sciences20060717

Title: Quantitative characterizations of proteome: dependence on the number of proteins considered.

Journal: Journal of proteome research20060701

Title: Activation of the rat scavenger receptor class B type I gene by PPARalpha.

Journal: Molecular and cellular endocrinology20060607

Title: Aspirin and PPAR-alpha activators inhibit monocyte chemoattractant protein-1 expression induced by high glucose concentration in human endothelial cells.

Journal: Vascular pharmacology20060601

Title: Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review.

Journal: International journal of nanomedicine20060601

Title: Separation of fibrate-type antihyperlipidemic drugs by capillary electrophoresis and their quantitation in pharmaceuticals.

Journal: Journal of pharmaceutical and biomedical analysis20060503

Title: Peroxisome proliferator-activated receptor alpha and gamma ligands differentially affect smooth muscle cell proliferation and migration.

Journal: The Journal of pharmacology and experimental therapeutics20060501

Title: Induction of hepatic transporters multidrug resistance-associated proteins (Mrp) 3 and 4 by clofibrate is regulated by peroxisome proliferator-activated receptor alpha.

Journal: The Journal of pharmacology and experimental therapeutics20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Complex graph matrix representations and characterizations of proteomic maps and chemically induced changes to proteomes.

Journal: Journal of proteome research20060501

Title: Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition20060501

Title: Peroxisome proliferator-activated receptor alpha agonist, clofibrate, has profound influence on myocardial fatty acid composition.

Journal: Chemico-biological interactions20060415

Title: The role of fibrates in a statin world.

Journal: Archives of internal medicine20060410

Title: Induction of renal 20-hydroxyeicosatetraenoic acid by clofibrate attenuates high-fat diet-induced hypertension in rats.

Journal: The Journal of pharmacology and experimental therapeutics20060401

Title: Activation of the peroxisome proliferator-activated receptor alpha pathway potentiates interleukin-1 receptor antagonist production in cytokine-treated chondrocytes.

Journal: Arthritis and rheumatism20060401

Title: FIELDS of dreams, fields of tears: a perspective on the fibrate trials.

Journal: International journal of clinical practice20060401

Title: Thomas Vicary and the anatomie of mans body.

Journal: Medical history20060401

Title: Clofibrate-induced apoptosis is mediated by Ca2+-dependent caspase-12 activation.

Journal: Life sciences20060313

Title: Localization of a portion of the liver isoform of fatty-acid-binding protein (L-FABP) to peroxisomes.

Journal: The Biochemical journal20060301

Title: Positive regulation of hepatic carnitine palmitoyl transferase 1A (CPT1A) activities by soy isoflavones and L-carnitine.

Journal: European journal of nutrition20060301

Title: Proteomic characterization of the effects of clofibrate on protein expression in rat liver.

Journal: Proteomics20060301

Title: Development of a toxicogenomics in vitro assay for the efficient characterization of compounds.

Journal: Pharmacogenomics20060301

Title: Expression of cytochrome P-450 4 enzymes in the kidney and liver: regulation by PPAR and species-difference between rat and human.

Journal: Molecular and cellular biochemistry20060301

Title: Hypolipidemic activity of Indan--1--acetic acids.

Journal: Nepal Medical College journal : NMCJ20060301

Title: Mortality from ischemic heart disease and diabetes mellitus (type 2) in four U.S. wheat-producing states: a hypothesis-generating study.

Journal: Environmental health perspectives20060201

Title: HMG-CoA reductase and PPARalpha are involved in clofibrate-induced apoptosis in human keratinocytes.

Journal: Apoptosis : an international journal on programmed cell death20060201

Title: Seasonal variations in concentrations of pharmaceuticals and personal care products in drinking water and reclaimed wastewater in southern California.

Journal: Environmental science & technology20060201

Title: Effect of clofibrate in jaundiced term neonates.

Journal: Indian journal of pediatrics20060201

Title: Effects of widely used pharmaceuticals and a detergent on oxidative stress biomarkers of the crustacean Artemia parthenogenetica.

Journal: Chemosphere20060101

Title: Transcriptional regulation of the PXR gene: identification and characterization of a functional peroxisome proliferator-activated receptor alpha binding site within the proximal promoter of PXR.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060101

Title: Cytochrome P450 expression-induction profile and chemically mediated alterations of the WIF-B9 cell line.

Journal: Biology of the cell20060101

Title: Process and dynamics of traditional selling wild edible mushrooms in tropical Mexico.

Journal: Journal of ethnobiology and ethnomedicine20060101

Title: Gene expression analysis of the hepatotoxicant methapyrilene in primary rat hepatocytes: an interlaboratory study.

Journal: Environmental health perspectives20060101

Title: On the dependence of a characterization of proteomics maps on the number of protein spots considered.

Journal: Journal of chemical information and modeling20060101

Title: Early events in the perception of lipopolysaccharides in the brown alga Laminaria digitata include an oxidative burst and activation of fatty acid oxidation cascades.

Journal: Journal of experimental botany20060101

Title: The hepatic transcriptome in human liver disease.

Journal: Comparative hepatology20060101

Title: Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists.

Journal: BMC bioinformatics20060101

Title: Hepatocellular proliferation in response to agonists of peroxisome proliferator-activated receptor alpha: a role for Kupffer cells?

Journal: Journal of carcinogenesis20060101

Title: Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha).

Journal: PPAR research20060101

Title: Liprin phosphorylation regulates binding to LAR: evidence for liprin autophosphorylation.

Journal: Biochemistry20051206

Title: Subchronic exposure to high-dose ACE-inhibitor moexipril induces catalase activity in rat liver.

Journal: Molecular and cellular biochemistry20051201

Title: Bexarotene and erlotinib for aerodigestive tract cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20051201

Title: The ACAT inhibitor VULM1457 significantly reduced production and secretion of adrenomedullin (AM) and down-regulated AM receptors on human hepatoblastic cells.

Journal: General physiology and biophysics20051201

Title: Optimal lipid modification: the rationale for combination therapy.

Journal: Vascular health and risk management20051201

Title: NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)alpha-mediated cardiovascular effects.

Journal: Mutation research20051111

Title: Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20051101

Title: Anticholesterolemic effect of 3,4-di(OH)-phenylpropionic amides in high-cholesterol fed rats.

Journal: Toxicology and applied pharmacology20051001

Title: Expression profiling of five different xenobiotics using a Caenorhabditis elegans whole genome microarray.

Journal: Chemosphere20051001

Title: [Pharmacology of fibrates].

Journal: Arquivos brasileiros de cardiologia20051001

Title: [Mechanisms of hepatotoxicity].

Journal: Arquivos brasileiros de cardiologia20051001

Title: [Hypolipidemic therapy in special situations: hypothyroidism and liver disease].

Journal: Arquivos brasileiros de cardiologia20051001

Title: Diet, lifestyle, and nonstatin trials: review of time to benefit.

Journal: The American journal of cardiology20050905

Title: Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.

Journal: Drug metabolism and disposition: the biological fate of chemicals20050901

Title: Modulation of peroxisome proliferator-activated receptors (PPARs) by PPAR(alpha)- and PPAR(gamma)-specific ligands and by 17beta-estradiol in isolated zebrafish hepatocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20050901

Title: Floratheasaponins A-C, acylated oleanane-type triterpene oligoglycosides with anti-hyperlipidemic activities from flowers of the tea plant (Camellia sinensis).

Journal: Journal of natural products20050901

Title: The hypolipidemic effect of a new ACAT inhibitor, VULM 1457, in diabetic-hypercholesterolaemic rats.

Journal: Die Pharmazie20050901

Title: Ten-year follow-up of familial hypercholesterolemia patients after intensive cholesterol-lowering therapy.

Journal: International heart journal20050901

Title: Pooling samples within microarray studies: a comparative analysis of rat liver transcription response to prototypical toxicants.

Journal: Physiological genomics20050811

Title: CYP94A1, a plant cytochrome P450-catalyzing fatty acid omega-hydroxylase, is selectively induced by chemical stress in Vicia sativa seedlings.

Journal: Planta20050801

Title: Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade.

Journal: Hypertension (Dallas, Tex. : 1979)20050801

Title: Eicosapentaenoic acid, but not oleic acid, stimulates beta-oxidation in adipocytes.

Journal: Lipids20050801

Title: Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals20050701

Title: Acute toxicity of widely used pharmaceuticals in aquatic species: Gambusia holbrooki, Artemia parthenogenetica and Tetraselmis chuii.

Journal: Ecotoxicology and environmental safety20050701

Title: Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: results of AIDS Clinical Trials Group 5108 Study.

Journal: Journal of acquired immune deficiency syndromes (1999)20050701

Title: Alligation alternate and the composition of medicines: arithmetic and medicine in early modern England.

Journal: Medical history20050701

Title: Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20050701

Title: The metastasis associated protein S100A4: role in tumour progression and metastasis.

Journal: British journal of cancer20050606

Title: Hepatic beta-oxidation and carnitine palmitoyltransferase I in neonatal pigs after dietary treatments of clofibric acid, isoproterenol, and medium-chain triglycerides.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20050601

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology20050601

Title: The linkage between Churg-Strauss syndrome and leukotriene receptor antagonists: fact or fiction?

Journal: Therapeutics and clinical risk management20050601

Title: Application of a two-stage Syrian hamster embryo cell transformation assay to cigarette smoke particulate matter.

Journal: Mutation research20050502

Title: Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23.

Journal: Biochemical pharmacology20050501

Title: Regulation of JH epoxide hydrolase versus JH esterase activity in the cabbage looper, Trichoplusia ni, by juvenile hormone and xenobiotics.

Journal: Journal of insect physiology20050501

Title: Gene expression fingerprint of uterine serous papillary carcinoma: identification of novel molecular markers for uterine serous cancer diagnosis and therapy.

Journal: British journal of cancer20050425

Title: n-Alkane and clofibrate, a peroxisome proliferator, activate transcription of ALK2 gene encoding cytochrome P450alk2 through distinct cis-acting promoter elements in Candida maltosa.

Journal: Biochemical and biophysical research communications20050401

Title: Differential expression and evolution of the Arabidopsis CYP86A subfamily.

Journal: Plant physiology20050301

Title: Fluorescence labeling method for aryl halides with 4-(4,5-diphenyl-1H-imidazol-2-yl)phenylboronic acid based on Suzuki coupling reaction.

Journal: Journal of chromatography. A20050225

Title: Alternative medical treatment strategies for chronic hyperplastic eosinophilic sinusitis.

Journal: Current opinion in otolaryngology & head and neck surgery20050201

Title: Synthesis and biological evaluation of new clofibrate analogues as potential PPARalpha agonists.

Journal: European journal of medicinal chemistry20050201

Title: Effect of clofibrate in jaundiced term newborns.

Journal: Indian journal of pediatrics20050201

Title: Cardiac medical therapy in patients after undergoing coronary artery bypass graft surgery: a review of randomized controlled trials.

Journal: Journal of the American College of Cardiology20050118

Title: Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart.

Journal: The Biochemical journal20050115

Title: Protective effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on glomerular protein permeability barrier.

Journal: Kidney international20050101

Title: A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons20050101

Title: Study of the liquid chromatography retention of some fibrate-type antihyperlipidemic drugs on C18 and CN columns: application for quantitation in pharmaceutical formulations.

Journal: Journal of AOAC International20050101

Title: Activity of peroxisomal enzymes, and levels of polyamines in LPA-transgenic mice on two different diets.

Journal: Lipids in health and disease20050101

Title: Investigations of clofibrate in alternative carcinogenicity models.

Journal: International journal of toxicology20050101

Title: Evaluation of the carcinogenic potential of clofibrate in the p53+/- mouse.

Journal: International journal of toxicology20050101

Title: Evaluation of the carcinogenic potential of clofibrate in the rasH2 mouse.

Journal: International journal of toxicology20050101

Title: Evaluation of the carcinogenic potential of clofibrate in the FVB/Tg.AC mouse after oral administration--part I.

Journal: International journal of toxicology20050101

Title: Evaluation of the carcinogenic potential of clofibrate in the FVB/Tg.AC mouse after dermal application--part II.

Journal: International journal of toxicology20050101

Title: Evaluation of the carcinogenic potential of clofibrate in the neonatal mouse.

Journal: International journal of toxicology20050101

Title: Fibrates.

Journal: Handbook of experimental pharmacology20050101

Title: A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.

Journal: Biochemical pharmacology20041215

Title: Acute and chronic effects of clofibrate and clofibric acid on the enzymes acetylcholinesterase, lactate dehydrogenase and catalase of the mosquitofish, Gambusia holbrooki.

Journal: Chemosphere20041201

Title: alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers.

Journal: The American journal of pathology20041101

Title: Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites.

Journal: Gastroenterology20041101

Title: Evidence for concurrent effects of exposure to environmental cadmium and lead on hepatic CYP2A6 phenotype and renal function biomarkers in nonsmokers.

Journal: Environmental health perspectives20041101

Title: Gene expression analysis of peroxisome proliferators- and phenytoin-induced hepatotoxicity using cDNA microarray.

Journal: The Journal of veterinary medical science20041101

Title: Fenofibrate impairs rat mitochondrial function by inhibition of respiratory complex I.

Journal: The Journal of pharmacology and experimental therapeutics20041001

Title: Evaluation of glutathione deficiency in rat livers by microarray analysis.

Journal: Biochemical pharmacology20041001

Title: Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro.

Journal: The British journal of dermatology20041001

Title: Co-induction of methyltransferase Rv0560c by naphthoquinones and fibric acids suggests attenuation of isoprenoid quinone action in Mycobacterium tuberculosis.

Journal: Canadian journal of microbiology20041001

Title: Effect of dexamethasone, 2-bromopalmitate and clofibrate on L-FABP mediated hepatoma proliferation.

Journal: The Journal of pharmacy and pharmacology20040901

Title: PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells.

Journal: Regulatory peptides20040815

Title: Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes.

Journal: Journal of medicinal chemistry20040812

Title: Dietary clofibrate inhibits induction of hepatic antioxidant enzymes by chronic estradiol in female ACI rats.

Journal: Toxicology20040805

Title: Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles.

Journal: Aquatic toxicology (Amsterdam, Netherlands)20040730

Title: PPARalpha agonists clofibrate and gemfibrozil inhibit cell growth, down-regulate hCG and up-regulate progesterone secretions in immortalized human trophoblast cells.

Journal: Biochemical pharmacology20040715

Title: Alcoholic liver injury in the rat is associated with reduced expression of peroxisome proliferator-alpha (PPARalpha)-regulated genes and is ameliorated by PPARalpha activation.

Journal: The Journal of pharmacology and experimental therapeutics20040701

Title: Visualization and quantitation of peroxisomes using fluorescent nanocrystals: treatment of rats and monkeys with fibrates and detection in the liver.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20040701

Title: Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20040601

Title: Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase.

Journal: Current rheumatology reports20040601

Title: Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver.

Journal: Biochemical pharmacology20040601

Title: The human semaphorin 6B gene is down regulated by PPARs.

Journal: Genomics20040601

Title: Ligand-induced expression of peroxisome proliferator-activated receptor alpha and activation of fatty acid oxidation enzymes in fatty liver.

Journal: European journal of clinical investigation20040601

Title: [Dyslipidemia in renal failure].

Journal: Nihon rinsho. Japanese journal of clinical medicine20040601

Title: A mouse model for alpha-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietary methyl-branched lipids.

Journal: Human molecular genetics20040501

Title: Identification of two Nereis virens (Annelida: Polychaeta) cytochromes P450 and induction by xenobiotics.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20040501

Title: Effect of serum cholesterol on the mRNA content of amyloid precursor protein in rat livers.

Journal: Toxicology letters20040421

Title: Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20040401

Title: Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20040401

Title: Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.

Journal: Fundamental & clinical pharmacology20040401

Title: Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling.

Journal: Chemical research in toxicology20040401

Title: Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression.

Journal: Environmental health perspectives20040301

Title: Clofibrate-induced gene expression changes in rat liver: a cross-laboratory analysis using membrane cDNA arrays.

Journal: Environmental health perspectives20040301

Title: Effects of human pharmaceuticals on cytotoxicity, EROD activity and ROS production in fish hepatocytes.

Journal: Toxicology20040301

Title: The up-regulation of hepatic acyl-CoA oxidase and cytochrome P450 4A1 mRNA expression by dietary oxidized frying oil is comparable between male and female rats.

Journal: Lipids20040301

Title: Stimulation of cardiac cardiolipin biosynthesis by PPARalpha activation.

Journal: Journal of lipid research20040201

Title: Peroxisome proliferator-activated receptor-gamma ligands: a pluripotent class of pharmacological agents that may prove to be useful for adjuvant treatment of sepsis and multiple organ dysfunction syndrome.

Journal: Critical care medicine20040201

Title: Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system.

Journal: Cancer science20040201

Title: Comparison of oxidative stress and changes of xenobiotic metabolizing enzymes induced by phthalates in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20040101

Title: Fibrates for treatment of the metabolic syndrome.

Journal: Current atherosclerosis reports20040101

Title: Normal and pathological human testes express hormone-sensitive lipase and the lipid receptors CLA-1/SR-BI and CD36.

Journal: Human pathology20040101

Title: Relationship between PPARalpha activation and NO on proximal tubular Na+ transport in the rat.

Journal: BMC pharmacology20040101

Title: Molecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genes.

Journal: BMC biochemistry20040101

Title: [Fibrates: mechanism of action, effect on levels of lipids and lipoproteins, risk of coronary events. Part 1. Clofibrate, gemfibrosil, besafibrate].

Journal: Kardiologiia20040101

Title: Ligand- and species-dependent activation of PPARalpha.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20040101

Title: On the effect of pharmaceuticals on bacterial nitrite oxidation.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research20040101

Title: The levels of soluble adhesion molecules in diabetic and nondiabetic patients with combined hyperlipoproteinemia and the effect of ciprofibrate therapy.

Journal: Angiology20040101

Title: Which is the best lipid-modifying strategy in metabolic syndrome and diabetes: fibrates, statins or both?

Journal: Cardiovascular diabetology20040101

Title: Phylogenetic tree facilitates the understanding of gene expression data on drug metabolizing enzymes obtained by microarray analysis.

Journal: Toxicology letters20031210

Title: Rat liver bile acid CoA:amino acid N-acyltransferase: expression, characterization, and peroxisomal localization.

Journal: Journal of lipid research20031201

Title: Characterization and cDNA cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster.

Journal: European journal of biochemistry20031201

Title: Temporal mismatch between induction of superoxide dismutase and ascorbate peroxidase correlates with high H2O2 concentration in seawater from clofibrate-treated red algae Kappaphycus alvarezii.

Journal: Archives of biochemistry and biophysics20031201

Title: Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation.

Journal: The Tohoku journal of experimental medicine20031201

Title: Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants.

Journal: Environmental toxicology and chemistry20031201

Title: [The effect of peroxisome proliferator-activated receptor alpha and gamma ligands on free fatty acid-induced INS-1 cell impairment].

Journal: Zhonghua nei ke za zhi20031201

Title: Peroxisome proliferator-activated receptor agonists inhibit interleukin-1beta-mediated nitric oxide production in cultured lacrimal gland acinar cells.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics20031201

Title: Regulation of triacylglycerol hydrolase expression by dietary fatty acids and peroxisomal proliferator-activated receptors.

Journal: Biochimica et biophysica acta20031130

Title: Regulation of cytochrome P-450 4A activity by peroxisome proliferator-activated receptors in the rat kidney.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension20031101

Title: Ozonation and H2O2/UV treatment of clofibric acid in water: a kinetic investigation.

Journal: Journal of hazardous materials20031031

Title: Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20031001

Title: Effect of a peroxysomal proliferator agent on intracellular cholesterol accumulation in cultured fibroblasts from Niemann-Pick type C disease patients.

Journal: Clinica chimica acta; international journal of clinical chemistry20031001

Title: [Anselmus Boetius de Boodt (1550-1632) Brugs humanist to the court of Austria].

Journal: Bulletin - Cercle Benelux d'histoire de la pharmacie20031001

Title: Simultaneous determination of clofibrate and its active metabolite clofibric acid in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet absorbance detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20030905

Title: Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR.

Journal: Pharmaceutical research20030901

Title: Comments on the MRC/BHF Heart Protection Study.

Journal: Lancet (London, England)20030830

Title: Rat NTE-related esterase is a membrane-associated protein, hydrolyzes phenyl valerate, and interacts with diisopropylfluorophosphate through a serine catalytic machinery.

Journal: Archives of biochemistry and biophysics20030815

Title: Effects of peroxisome proliferators gemfibrozil and clofibrate on syntheses of dolichol and cholesterol in rat liver.

Journal: Journal of biochemistry20030801

Title: Peroxisome proliferator-activated receptor alpha induces rat sterol carrier protein x promoter activity through two peroxisome proliferator-response elements.

Journal: Molecular and cellular endocrinology20030731

Title: In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea.

Journal: Drug metabolism and disposition: the biological fate of chemicals20030701

Title: Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells.

Journal: The Journal of pharmacology and experimental therapeutics20030601

Title: Induction of the expression of the peroxisome proliferator-activated receptor alpha (PPARalpha) by clofibrate in jerboa tissues.

Journal: Microscopy research and technique20030601

Title: Fibrates and their newly synthesized glycinate or glycinate-methylester derivatives: comparison of the interactions with liver cytochrome P450 dependent monooxygenase- and oxidase-functions in vitro.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie20030601

Title: In vivo stabilization of nuclear retinoid X receptor alpha in the presence of peroxisome proliferator-activated receptor alpha.

Journal: FEBS letters20030522

Title: UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytes.

Journal: Chemico-biological interactions20030506

Title: Mechanisms involved in growth inhibition induced by clofibrate in hepatoma cells.

Journal: Toxicology20030503

Title: Differential levels of gamma-glutamyl transferase activity and apolipoprotein CIII in men on either statin or fibrate therapy.

Journal: Diabetes care20030501

Title: Reduction of all-trans-retinal in the mouse liver peroxisome fraction by the short-chain dehydrogenase/reductase RRD: induction by the PPAR alpha ligand clofibrate.

Journal: Biochemistry20030415

Title: Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.

Journal: Archives of internal medicine20030324

Title: Fatty acid binding protein is a major determinant of hepatic pharmacokinetics of palmitate and its metabolites.

Journal: American journal of physiology. Gastrointestinal and liver physiology20030301

Title: Distinct effects of ketone bodies on down-regulation of cell surface insulin receptor and insulin receptor substrate-1 phosphorylation in adrenal chromaffin cells.

Journal: The Journal of pharmacology and experimental therapeutics20030301

Title: Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20030301

Title: Age-dependent effects of nongenotoxic hepatocarcinogens on liver apoptosis in vivo.

Journal: Mechanisms of ageing and development20030301

Title: Aldehyde dehydrogenase 3 expression is decreased by clofibrate via PPAR gamma induction in JM2 rat hepatoma cell line.

Journal: Chemico-biological interactions20030201

Title: cDNA cloning and characterization of the third isoform of human peroxin Pex11p.

Journal: Biochemical and biophysical research communications20030124

Title: Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action.

Journal: Bioorganic & medicinal chemistry letters20030120

Title: Apoptosis induced by clofibrate in Yoshida AH-130 hepatoma cells: role of HMG-CoA reductase.

Journal: Journal of lipid research20030101

Title: Peroxisome proliferative drugs do not induce an increase of rat mevalonate pyrophosphate decarboxylase.

Journal: Biological & pharmaceutical bulletin20030101

Title: Transdermal delivery of nalbuphine and its prodrugs by electroporation.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20030101

Title: Inflammation and atherosclerosis in end-stage renal disease.

Journal: Blood purification20030101

Title: Prevalidation of a rat liver foci bioassay (RLFB) based on results from 1600 rats: a study report.

Journal: Toxicologic pathology20030101

Title: Mepanipyrim, a novel inhibitor of pharmacologically induced Golgi dispersion.

Journal: Bioscience, biotechnology, and biochemistry20030101

Title: Effect of topical PPARbeta/delta and PPARgamma agonists on plaque psoriasis. A pilot study.

Journal: Dermatology (Basel, Switzerland)20030101

Title: [Antilipemics: results of large studies].

Journal: Therapie20030101

Title: Transcription profiling distinguishes dose-dependent effects in the livers of rats treated with clofibrate.

Journal: Toxicologic pathology20030101

Title: A patient with hyperlipidemia who had a gallbladder stone caused by administration of fenofibrate.

Journal: The Kurume medical journal20030101

Title: [Granada Professorships of the Conservatorio de Artes (Art School) (1833-1845)].

Journal: Dynamis (Granada, Spain)20030101

Title: Treatment of glomerular endothelial dysfunction in steroid-resistant nephrosis with Ganoderma lucidum, vitamins C, E and vasodilators.

Journal: Clinical hemorheology and microcirculation20030101

Title: NAD levels in the rat primary cultured hepatocytes affected by peroxisome-proliferators.

Journal: Advances in experimental medicine and biology20030101

Title: Nuclear receptor agonists stimulate release of arachidonic acid from rat liver cells.

Journal: Prostaglandins, leukotrienes, and essential fatty acids20021201

Title: Agonists of peroxisome-proliferator activated receptor-alpha (clofibrate and WY14643) reduce renal ischemia/reperfusion injury in the rat.

Journal: Medical science monitor : international medical journal of experimental and clinical research20021201

Title: PPAR-alpha ligands inhibit H2O2-mediated activation of transforming growth factor-beta1 in human mesangial cells.

Journal: Antioxidants & redox signaling20021201

Title: Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes.

Journal: The Journal of biological chemistry20021129

Title: Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms.

Journal: Archives of biochemistry and biophysics20021115

Title: [Discovery and development of a new insulin sensitizing agent, pioglitazone].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20021101

Title: Safety of archaeosome adjuvants evaluated in a mouse model.

Journal: Journal of liposome research20021101

Title: Clofibrate improves glucose tolerance in fat-fed rats but decreases hepatic glucose consumption capacity.

Journal: Journal of hepatology20021001

Title: Establishing and sculpting the synapse in Drosophila and C. elegans.

Journal: Current opinion in neurobiology20021001

Title: Peroxisomes of the nematode Caenorhabditis elegans: distribution and morphological characteristics.

Journal: Histochemistry and cell biology20021001

Title: The science behind statins and fibrates.

Journal: International journal of clinical practice. Supplement20021001

Title: Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals20020901

Title: PPAR agonists amplify iNOS expression while inhibiting NF-kappaB: implications for mesangial cell activation by cytokines.

Journal: Journal of the American Society of Nephrology : JASN20020901

Title: Effects of in vivo treatment of rats with trimethyltin chloride on respiratory properties of rat liver mitochondria.

Journal: Biochemical pharmacology20020815

Title: Effects of fatty acids on mitochondrial beta-oxidation enzyme gene expression in renal cell lines.

Journal: American journal of physiology. Renal physiology20020801

Title: Enhanced activity of Ca2+-activated K+ channels by 1-[2-hydroxy-3-propyl-4-[(1H-tetrazol-5-yl)butoxyl]phenyl] ethanone (LY-171883) in neuroendocrine and neuroblastoma cell lines.

Journal: Journal of cellular physiology20020801

Title: Renal cytochrome p450 oxygenases and preglomerular vascular response to arachidonic acid and endothelin-1 following ischemia/reperfusion.

Journal: The Journal of pharmacology and experimental therapeutics20020801

Title: Peroxisome proliferator-activated receptor alpha in the human breast cancer cell lines MCF-7 and MDA-MB-231.

Journal: Molecular carcinogenesis20020801

Title: Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20020701

Title: Ligands of the peroxisome proliferator-activated receptor-PPAR-a reduce myocardial infarct size.

Journal: Medical science monitor : international medical journal of experimental and clinical research20020701

Title: Detection of pharmaceutical contaminations of river, pond, and tap water from Cologne (Germany) and surroundings.

Journal: International journal of hygiene and environmental health20020701

Title: Influence of peroxisome proliferator-activated receptor alpha agonists on the intracellular turnover and secretion of apolipoprotein (Apo) B-100 and ApoB-48.

Journal: The Journal of biological chemistry20020621

Title: Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2.

Journal: Brain research20020621

Title: Gene expression analysis reveals chemical-specific profiles.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20020601

Title: Prediction of compound signature using high density gene expression profiling.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20020601

Title: PPARgamma ligands suppress proliferation of human urothelial basal cells in vitro.

Journal: Journal of cellular physiology20020601

Title: Chiral inversion of (R)-(-)-fenoprofen in guinea-pigs pretreated with clofibrate.

Journal: Veterinary research communications20020601

Title: Computational selection of distinct class- and subclass-specific gene expression signatures.

Journal: Journal of biomedical informatics20020601

Title: Exposure simulation for pharmaceuticals in European surface waters with GREAT-ER.

Journal: Toxicology letters20020510

Title: Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Delta(12,14)(12,14)-prostaglandin J(2) in activated human astrocytes, but not in human brain macrophages.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020501

Title: Lipid-lowering drug use and cardiovascular events after myocardial infarction.

Journal: The Annals of pharmacotherapy20020501

Title: Activation of the immune system and inflammatory activity in relation to markers of atherothrombotic disease and atherosclerosis in rheumatoid arthritis.

Journal: The Journal of rheumatology20020501

Title: Blunted induction of hepatic CYP4A in TNF (p55-/-/p75-/-) double receptor knockout mice following clofibrate treatment.

Journal: Pharmaceutical research20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: Role of hypolipidemic drug clofibrate in altering iron regulatory proteins IRP1 and IRP2 activities and hepatic iron metabolism in rats fed a low-iron diet.

Journal: Toxicology and applied pharmacology20020415

Title: Troglitazone suppresses the secretion of type I collagen by mesangial cells in vitro.

Journal: Kidney international20020401

Title: Pharmacological interventions for the treatment of neonatal jaundice.

Journal: Seminars in neonatology : SN20020401

Title: Getting a GRIP on liprins.

Journal: Neuron20020328

Title: Clofibrate-induced relocation of phosphatidylcholine transfer protein to mitochondria in endothelial cells.

Journal: Experimental cell research20020310

Title: Myopathy and rhabdomyolysis with lipid-lowering drugs.

Journal: Toxicology letters20020310

Title: Potentiation of TNF-alpha-stimulated group IIA phospholipase A(2) expression by peroxisome proliferator-activated receptor alpha activators in rat mesangial cells.

Journal: Journal of the American Society of Nephrology : JASN20020301

Title: Presence and features of fatty acyl-CoA binding activity in rat hepatic peroxisomes.

Journal: Journal of biochemistry20020301

Title: Effect of clofibrate administration on the esterification and deesterification of steroid hormones by liver and extrahepatic tissues in rats.

Journal: Biochemical pharmacology20020301

Title: In vitro induction of bilirubin conjugation in primary rat hepatocyte culture.

Journal: Biochemical and biophysical research communications20020215

Title: Characterization of catechol glucuronidation in rat liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals20020201

Title: Do lipid-lowering drugs cause erectile dysfunction? A systematic review.

Journal: Family practice20020201

Title: Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation.

Journal: Free radical biology & medicine20020201

Title: Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.

Journal: Biochemical and biophysical research communications20020111

Title: CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation.

Journal: Drug metabolism and disposition: the biological fate of chemicals20020101

Title: Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models.

Journal: The Journal of investigative dermatology20020101

Title: Comparison of various characteristics of women who do and do not attend for breast cancer screening.

Journal: Breast cancer research : BCR20020101

Title: Eighth World Congress of Intensive and Critical Care Medicine, 28 October-1 November 2001, Sydney, Australia: Harm minimization and effective risk management.

Journal: Critical care (London, England)20020101

Title: Peroxisome proliferator-activated receptor ligands as antiatherogenic agents: panacea or another Pandora's box?

Journal: Journal of cardiovascular pharmacology and therapeutics20020101

Title: Interventions in the management of serum lipids for preventing stroke recurrence.

Journal: The Cochrane database of systematic reviews20020101

Title: The role of the mode of delivery in the alteration of intrapartum pathological cervical cytologic findings during the postpartum period.

Journal: European journal of gynaecological oncology20020101

Title: Protection against acetaminophen hepatotoxicity by clofibrate pretreatment: role of catalase induction.

Journal: Journal of biochemical and molecular toxicology20020101

Title: The anatomy of a clinical trial. The West of Scotland Coronary Prevention Study.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre20020101

Title: Effect of garlic on cardiovascular disorders: a review.

Journal: Nutrition journal20020101

Title: Strategies for minimizing hyperlipidemia after cardiac transplantation.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions20020101

Title: The transcription of the peroxisome proliferator-activated receptor alpha gene is regulated by protein kinase C.

Journal: Toxicology letters20011215

Title: Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5' nuclease assay (TaqMan).

Journal: Mutation research20011212

Title: The use of fibrates and of statins in preventing atherosclerosis in diabetes.

Journal: Current opinion in lipidology20011201

Title: Peroxisome proliferator-activated receptor alpha (PPAR alpha) agonist, WY-14,643, increased transcription of myosin light chain-2 in cardiomyocytes.

Journal: The Journal of toxicological sciences20011201

Title: Metabolic Syndromes Associated With HIV: Mitigating the Side Effects of Drug Therapy.

Journal: The Physician and sportsmedicine20011201

Title: A systematic gene expression screen of Caenorhabditis elegans cytochrome P450 genes reveals CYP35 as strongly xenobiotic inducible.

Journal: Archives of biochemistry and biophysics20011115

Title: Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices.

Journal: Journal of pineal research20011101

Title: Autoantibodies to lipids in bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome.

Journal: Critical care medicine20011001

Title: Mechanism of clofibrate hepatotoxicity: mitochondrial damage and oxidative stress in hepatocytes.

Journal: Free radical biology & medicine20010901

Title: PPARalpha-dependent induction of liver microsomal esterification of estradiol and testosterone by a prototypical peroxisome proliferator.

Journal: Endocrinology20010801

Title: Binding constant determination of drugs toward subdomain IIIA of human serum albumin by near-infrared dye-displacement capillary electrophoresis.

Journal: Electrophoresis20010801

Title: Characterization of clofibrate-induced retrograde Golgi membrane movement to the endoplasmic reticulum: clofibrate distinguishes the Golgi from the trans Golgi network.

Journal: Bioscience, biotechnology, and biochemistry20010801

Title: Tocopherols are metabolized in HepG2 cells by side chain omega-oxidation and consecutive beta-oxidation.

Journal: Free radical biology & medicine20010715

Title: Expression and characterization of recombinant rat Acyl-CoA synthetases 1, 4, and 5. Selective inhibition by triacsin C and thiazolidinediones.

Journal: The Journal of biological chemistry20010706

Title: The biochemistry of hypo- and hyperlipidemic fatty acid derivatives: metabolism and metabolic effects.

Journal: Progress in lipid research20010701

Title: Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease.

Journal: Kidney international20010701

Title: Hormonal regulation of multiple promoters of the rat mitochondrial glycerol-3-phosphate dehydrogenase gene: identification of a complex hormone-response element in the ubiquitous promoter B.

Journal: European journal of biochemistry20010701

Title: Peroxisome proliferator-activated receptors (PPAR) and the mitochondrial aldehyde dehydrogenase (ALDH2) promoter in vitro and in vivo.

Journal: Alcoholism, clinical and experimental research20010701

Title: Comparative studies on nicotinic acid derivatives as hypolipoproteinemic agents.

Journal: Pakistan journal of pharmaceutical sciences20010701

Title: Combined interferon-alfa, 13-cis-retinoic acid, and alpha-tocopherol in locally advanced head and neck squamous cell carcinoma: novel bioadjuvant phase II trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology20010615

Title: Three-dimensional high voltage electron microscopy of thick biological specimens.

Journal: Micron (Oxford, England : 1993)20010601

Title: Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants.

Journal: The Journal of pharmacology and experimental therapeutics20010601

Title: Characterization of the promoter region of the human peroxisomal multifunctional enzyme type 2 gene.

Journal: Biochemical and biophysical research communications20010601

Title: Accumulation of medium chain acyl-CoAs during beta-oxidation of long chain fatty acid by isolated peroxisomes from rat liver.

Journal: Biological & pharmaceutical bulletin20010601

Title: Localization of mRNAs encoding peroxisomal proteins in cell culture by non-radioactive in situ hybridization. Comparison of rat and human hepatoma cells and their responses to two divergent hypolipidemic drugs.

Journal: Histochemistry and cell biology20010601

Title: Modulation of cytosolic phospholipase A(2) by PPAR activators in human preadipocytes.

Journal: Journal of lipid research20010501

Title: Peroxisome-proliferator-activated receptors as physiological sensors of fatty acid metabolism: molecular regulation in peroxisomes.

Journal: Biochemical Society transactions20010501

Title: Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays.

Journal: Physiological genomics20010427

Title: Stimulatory effect of clofibrate on the action of estradiol in the mammary gland but not in the uterus of rats.

Journal: The Journal of pharmacology and experimental therapeutics20010401

Title: Cytochrome P450 1A1 and 4A activities in isolated rat spleen lymphocytes.

Journal: Die Pharmazie20010401

Title: WY-14,643 and other agonists of the peroxisome proliferator-activated receptor reveal a new mode of action for salicylic acid in soybean disease resistance.

Journal: Planta20010401

Title: Effect of bezafibrate and clofibrate on the heme-iron geometry of ferrous nitrosylated heme-human serum albumin: an EPR study.

Journal: Journal of inorganic biochemistry20010401

Title: The expression of PPAR-associated genes is modulated through postnatal development of PPAR subtypes in the small intestine.

Journal: Biochimica et biophysica acta20010330

Title: Differential induction of rat hepatic cytochromes P450 3A1, 3A2, 2B1, 2B2, and 2E1 in response to pyridine treatment.

Journal: Drug metabolism and disposition: the biological fate of chemicals20010301

Title: Cytochrome p450-dependent metabolism of trichloroethylene in rat kidney.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20010301

Title: Allosteric modification of oxygen delivery by hemoglobin.

Journal: Anesthesia and analgesia20010301

Title: [Overviews of fibrate].

Journal: Nihon rinsho. Japanese journal of clinical medicine20010301

Title: Long-chain fatty acids regulate liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome-proliferator-activated receptor alpha (PPARalpha)-independent pathway.

Journal: The Biochemical journal20010215

Title: Molecular cloning and regulation of expression of two novel mouse CYP4F genes: expression in peroxisome proliferator-activated receptor alpha-deficient mice upon lipopolysaccharide and clofibrate challenges.

Journal: The Journal of pharmacology and experimental therapeutics20010201

Title: The peroxisomal proliferator clofibrate enhances the hepatic cytoplasmic movement of fatty acids in rats.

Journal: Hepatology (Baltimore, Md.)20010201

Title: Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas20010201

Title: Major clofibrate effects on liver and plasma lipids are independent of changes in polyunsaturated fatty acid composition induced by dietary fat.

Journal: Lipids20010201

Title: Effects of polyunsaturated fatty acids and clofibrate on chicken stearoyl-coA desaturase 1 gene expression.

Journal: Biochemical and biophysical research communications20010112

Title: The transcriptional and DNA binding activity of peroxisome proliferator-activated receptor alpha is inhibited by ethanol metabolism. A novel mechanism for the development of ethanol-induced fatty liver.

Journal: The Journal of biological chemistry20010105

Title: Stimulatory effect of clofibrate and gemfibrozil administration on the formation of fatty acid esters of estradiol by rat liver microsomes.

Journal: The Journal of pharmacology and experimental therapeutics20010101

Title: Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A.

Journal: Journal of biochemical and molecular toxicology20010101

Title: [Necrotizing myopathies].

Journal: Ryoikibetsu shokogun shirizu20010101

Title: How well tolerated are lipid-lowering drugs?

Journal: Drugs & aging20010101

Title: Neonatal mouse model: review of methods and results.

Journal: Toxicologic pathology20010101

Title: The syrian hamster embryo (SHE) cell transformation assay: review of the methods and results.

Journal: Toxicologic pathology20010101

Title: Tg.AC genetically altered mouse: assay working group overview of available data.

Journal: Toxicologic pathology20010101

Title: Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation.

Journal: Advances in experimental medicine and biology20010101

Title: [Fibrate influence on lipids and insulin resistance in patients with metabolic syndrome].

Journal: Przeglad lekarski20010101

Title: [A 50-year history of new drugs in Japan: the developments and trends of antihyperlipidemic drugs].

Journal: Yakushigaku zasshi20010101

Title: Peroxisome proliferator-activated receptor alpha-null mice lack resistance to acetaminophen hepatotoxicity following clofibrate exposure.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20001001

Title: Keratinocyte differentiation in hyperproliferative epidermis: topical application of PPARalpha activators restores tissue homeostasis.

Journal: The Journal of investigative dermatology20000901

Title: Evidence against the peroxisome proliferator-activated receptor alpha (PPARalpha) as the mediator for polyunsaturated fatty acid suppression of hepatic L-pyruvate kinase gene transcription.

Journal: Journal of lipid research20000501

Title: Involvement of the peroxisome proliferator-activated receptor alpha in regulating long-chain acyl-CoA thioesterases.

Journal: Journal of lipid research20000501

Title: Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro.

Journal: Biochemical and biophysical research communications20000413

Title: The PPARs: from orphan receptors to drug discovery.

Journal: Journal of medicinal chemistry20000224

Title: Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism.

Journal: Cell biochemistry and biophysics20000101

Title: The slow induction of resistant hepatocytes during initiation of hepatocarcinogenesis by the nongenotoxic carcinogen clofibrate.

Journal: Experimental and molecular pathology19991201

Title: Mitochondrial damage by the 'pro-oxidant' peroxisomal proliferator clofibrate.

Journal: Free radical biology & medicine19991101

Title: Hypophysectomy and/or peroxisome proliferators strongly influence the levels of phase II xenobiotic metabolizing enzymes in rat testis.

Journal: Chemico-biological interactions19990930

Title: The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat.

Journal: Archives of toxicology19990901

Title: Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation.

Journal: The Journal of toxicological sciences19990801

Title: Structure, evolution, and liver-specific expression of sterol 12alpha-hydroxylase P450 (CYP8B).

Journal: Journal of biochemistry19990701

Title: Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth.

Journal: Diabetes19990601

Title: Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-alpha.

Journal: Blood19990501

Title: A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.

Journal: Xenobiotica; the fate of foreign compounds in biological systems19990301

Title: Analysis of cytochrome P450 and phase II conjugating enzyme expression in adult male rat hepatocytes.

Journal: In vitro cellular & developmental biology. Animal19990301

Title: Inhibition of transforming growth factor beta1-induced hepatoma cell apoptosis by liver tumor promoters: characterization of primary signaling events and effects on CPP32-like caspase activity.

Journal: Cell death and differentiation19990201

Title: N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents.

Journal: Journal of medicinal chemistry19981203

Title: Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha.

Journal: Thrombosis and haemostasis19981201

Title: Reduced cholesterol accumulation and improved deficient peroxisomal functions in a murine model of Niemann-Pick type C disease upon treatment with peroxisomal proliferators.

Journal: Biochemical pharmacology19981101

Title: Dietary lipids regulate beta-oxidation enzyme gene expression in the developing rat kidney.

Journal: The American journal of physiology19981101

Title: The effect of non-genotoxic carcinogens, phenobarbital and clofibrate, on the relationship between reactive oxygen species, antioxidant enzyme expression and apoptosis.

Journal: Carcinogenesis19981001

Title: Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.

Journal: Proceedings of the National Academy of Sciences of the United States of America19980929

Title: Glucocorticoids repress induction by thiazolidinediones, fibrates, and fatty acids of phosphoenolpyruvate carboxykinase gene expression in adipocytes.

Journal: Journal of cellular biochemistry19980301

Title: Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells.

Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research19980301

Title: Clinical pharmacokinetics of fibric acid derivatives (fibrates).

Journal: Clinical pharmacokinetics19980201

Title: Induction of P4504A activity improves pressure-natriuresis in Dahl S rats.

Journal: Hypertension (Dallas, Tex. : 1979)19980101

Title: Hepatic hyperplasia and cancer in rats: metabolic alterations associated with cell growth.

Journal: Gastroenterology19970701

Title: Effects of peroxisome proliferators and/or hypothyroidism on xenobiotic-metabolizing enzymes in rat testis.

Journal: Chemico-biological interactions19970502

Title: Rapid and extensive lethal action of clofibrate on hepatoma cells in vitro.

Journal: Cell death and differentiation19970401

Title: Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells.

Journal: The Journal of biological chemistry19970207

Title: Clofibrate feeding to Sprague-Dawley rats increases endogenous biosynthesis of oxalate and causes hyperoxaluria.

Journal: Metabolism: clinical and experimental19970201

Title: Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.

Journal: Toxicology and applied pharmacology19970101

Title: Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey.

Journal: Arteriosclerosis, thrombosis, and vascular biology19970101

Title: Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver.

Journal: Carcinogenesis19961101

Title: Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression.

Journal: Proceedings of the National Academy of Sciences of the United States of America19960903

Title: Growth regulation by peroxisome proliferators: opposing activities in early and late G1.

Journal: Cancer research19960715

Title: Peroxisome proliferator-activated receptor alpha required for gene induction by dehydroepiandrosterone-3 beta-sulfate.

Journal: Molecular pharmacology19960701

Title: Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion.

Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology19960201

Title: Effect of structurally diverse peroxisome proliferators on rat hepatic sulfotransferase.

Journal: Chemico-biological interactions19960105

Title: Thyromimetic action of the peroxisome proliferators clofibrate, perfluorooctanoic acid, and acetylsalicylic acid includes changes in mRNA levels for certain genes involved in mitochondrial biogenesis.

Journal: Archives of biochemistry and biophysics19960101

Title: The possible roles of hyperlipidemia and mononuclear cells in glomeruli in puromycin aminonucleoside nephrosis in rats.

Journal: Japanese journal of pharmacology19960101

Title: Immunohistochemical demonstration of the gap junctional protein connexin 32 and proliferating cell nuclear antigen in glutathione S-transferase placental form-negative lesions of rat liver induced by diethylnitrosamine and clofibrate.

Journal: Toxicologic pathology19960101

Title: Fatty acids and fibrates are potent inducers of transcription of the phosphenolpyruvate carboxykinase gene in adipocytes.

Journal: European journal of biochemistry19951201

Title: Clofibrate-induced neoplastic development in the rat liver is associated with decreased connexin 32 expression but not with a co-ordinated shift in expression of marker enzymes.

Journal: Toxicology letters19951201

Title: Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.

Journal: Journal of lipid research19951201

Title: Suppression of rat glutathione transferase P expression by peroxisome proliferators: interaction between Jun and peroxisome proliferator-activated receptor alpha.

Journal: Cancer research19951115

Title: Currently available hypolipidaemic drugs and future therapeutic developments.

Journal: Bailliere's clinical endocrinology and metabolism19951001

Title: Hepatic oxidative stress and related defenses during treatment of mice with acetylsalicylic acid and other peroxisome proliferators.

Journal: Journal of biochemical toxicology19950401

Title: Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates: relationship with peroxisome proliferation.

Journal: British journal of pharmacology19950401

Title: Effect of high fat diet on liver microsomal oxygenations in ferret.

Journal: Xenobiotica; the fate of foreign compounds in biological systems19941101

Title: The effects of clofibrate and bezafibrate on cholesterol metabolism in the liver of the male rat.

Journal: Lipids19941101

Title: Mitochondrial 2,4-dienoyl-CoA reductases in the rat: differential responses to clofibrate treatment.

Journal: Journal of lipid research19941001

Title: Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate.

Journal: Carcinogenesis19940801

Title: Modification of hepatic immunoglobulin heavy chain binding protein (BiP/Grp78) following exposure to structurally diverse peroxisome proliferators.

Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology19940701

Title: Regulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectors.

Journal: The Biochemical journal19940515

Title: Charge modification in rodent hepatic Grp78/BiP following exposure to structurally diverse peroxisome proliferators.

Journal: Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society19940101

Title: A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids.

Journal: Molecular pharmacology19940101

Title: Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver.

Journal: Biological & pharmaceutical bulletin19931201

Title: Further studies on the involvement of selenium in peroxisome proliferation in rat liver. Comparison of effects with clofibric acid and perfluorooctanoic acid and the pharmacokinetics of [14C]clofibrate.

Journal: Biochemical pharmacology19931117

Title: Inhibition of lipogenesis in rat brown adipose tissue by clofibrate.

Journal: Biochemical pharmacology19931019

Title: Regulation of xanthine dehydrogenase in rat liver in response to peroxisome proliferators.

Journal: Biochemical and biophysical research communications19930915

Title: Coordinate induction of acyl-CoA binding protein, fatty acid binding protein and peroxisomal beta-oxidation by peroxisome proliferators.

Journal: Biochimica et biophysica acta19930606

Title: cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor.

Journal: Biochemistry19930601

Title: Lack of peroxisomal enzyme inducibility in rat hepatic preneoplastic lesions induced by mutagenic carcinogens: contrasted expression of glutathione S-transferase P form and enoyl CoA hydratase.

Journal: Carcinogenesis19930301

Title: Specific repression of transthyretin gene expression in rat liver by a peroxisome proliferator clofibrate.

Journal: Biochemical and biophysical research communications19921030

Title: The mechanism underlying the hypolipemic effect of perfluorooctanoic acid (PFOA), perfluorooctane sulphonic acid (PFOSA) and clofibric acid.

Journal: Biochimica et biophysica acta19920922

Title: Modifying effects of various chemicals on tumor development in a rat wide-spectrum organ carcinogenesis model.

Journal: Japanese journal of cancer research : Gann19920801

Title: [Iatrogeny. The importance of clinical diagnosis. Myopathies induced by clofibrate].

Journal: Arquivos de neuro-psiquiatria19920301

Title: Loss of peroxisomal enzyme expression in preneoplastic and neoplastic lesions induced by peroxisome proliferators in rat livers.

Journal: Carcinogenesis19920201

Title: Drug-induced gallbladder disease. Incidence, aetiology and management.

Journal: Drug safety19920101

Title: Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.

Journal: Journal of medicinal chemistry19911001

Title: Molecular basis for the lack of bilirubin-specific and 3-methylcholanthrene-inducible UDP-glucuronosyltransferase activities in Gunn rats. The two isoforms are encoded by distinct mRNA species that share an identical single base deletion.

Journal: The Journal of biological chemistry19910925

Title: Gemfibrozil-induced myopathy.

Journal: Archives of internal medicine19910901

Title: Induction of the cytochrome P450 I and IV families and peroxisomal proliferation in the liver of rats treated with benoxaprofen. Possible implications in its hepatotoxicity.

Journal: Biochemical pharmacology19910621

Title: Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver.

Journal: Chemical & pharmaceutical bulletin19910501

Title: Effect of simvastatin (MK-733) on plasma triacylglycerol levels in rats.

Journal: Biochemical pharmacology19910415

Title: Effect of ethanol administration on metabolism of lipids in heart and aorta in isoproterenol induced myocardial infarction in rats.

Journal: Indian journal of experimental biology19910301

Title: On the mechanism of the hepatocarcinogenicity of peroxisome proliferators.

Journal: Chemico-biological interactions19910101

Title: Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Journal: Japanese journal of cancer research : Gann19901201

Title: Toxicological studies on a benzofurane derivative. II. Demonstration of peroxisome proliferation in rat liver.

Journal: Toxicology and applied pharmacology19901201

Title: Characterization of the hepatic responses to the short-term administration of ciprofibrate in several rat strain. Co-induction of microsomal cytochrome P-450 IVA1 and peroxisome proliferation.

Journal: Biochemical pharmacology19900901

Title: Long-term effects of peroxisome proliferators on the balance between hydrogen peroxide-generating and scavenging capacities in the liver of Fischer-344 rats.

Journal: Toxicology19900801

Title: Induction of fatty acid binding protein by peroxisome proliferators in primary hepatocyte cultures and its relationship to the induction of peroxisomal beta-oxidation.

Journal: Biochimica et biophysica acta19900423

Title: Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver.

Journal: Carcinogenesis19900401

Title: Biotransformation of N,N',N''-triethylenethiophosphoramide: oxidative desulfuration to yield N,N',N''-triethylenephosphoramide associated with suicide inactivation of a phenobarbital-inducible hepatic P-450 monooxygenase.

Journal: Cancer research19900201

Title: Effects of hepatic peroxisome proliferators and 12-O-tetradecanoyl phorbol-13-acetate on catalase and other enzyme activities of embryonic cells in vitro.

Journal: Biochemical pharmacology19900201

Title: Peroxisome proliferator-induced alterations in the expression and modification of rat hepatocyte plasma membrane proteins.

Journal: Cancer research19900201

Title: Clofibrate-induced myopathy in a patient with primary hypothyroidism.

Journal: Japanese journal of medicine19900101

Title: Morphological transformation and catalase activity of Syrian hamster embryo cells treated with hepatic peroxisome proliferators, TPA and nickel sulphate.

Journal: Cell biology and toxicology19900101

Title: [Bone marrow aplasia associated with ticlopidine treatment in a patient with idiopathic hypothyroidism].

Journal: La Clinica terapeutica19890930

Title: The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.

Journal: DNA (Mary Ann Liebert, Inc.)19890901

Title: Studies with etofibrate in the rat. Part I: Effects on glycerol, free fatty acid and triacylglycerol metabolism.

Journal: Biochimica et biophysica acta19881104

Title: Hypolipidemic drug clofibrate promotes hepatic tumor.

Journal: Biochemistry international19881001

Title: [Atypical muscular syndrome with myolysis during long-term treatment with fibrates].

Journal: Archives des maladies du coeur et des vaisseaux19880701

Title: Interactions of inhibitors of carnitine palmitoyltransferase I and fibrates in cultured hepatocytes.

Journal: The Biochemical journal19880701

Title: Clofibrate increases the number of peroxisomes and of lamellar bodies in alveolar cells type II of the rat lung.

Journal: European journal of cell biology19880401

Title: Hepatic epoxide hydrolase activities and their induction by clofibrate and diethylhexylphthalate in various strains of mice.

Journal: Biochemical pharmacology19871215

Title: Absence of gamma-glutamyltranspeptidase activity in lung metastasis in rats with hepatocellular carcinomas induced by ciprofibrate, a peroxisome proliferator.

Journal: Cancer letters19871201

Title: Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

Journal: European journal of biochemistry19871102

Title: The effect of tridiphane (2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane) on hepatic epoxide-metabolizing enzymes: indications of peroxisome proliferation.

Journal: Toxicology and applied pharmacology19870615

Title: Effects of some hypolipidemic agents on biochemical values and hepatic peroxisomal enzymes in rats: comparison of probucol, CGA, KCD-232, MLM-160, AL-369 and clinofibrate with clofibrate.

Journal: Journal of pharmacobio-dynamics19870301

Title: Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

Journal: The Journal of biological chemistry19870115

Title: Peroxisome proliferator-induced hepatocarcinogenesis: levels of activating and detoxifying enzymes in hepatocellular carcinomas induced by ciprofibrate.

Journal: Carcinogenesis19870101

Title: Adverse effects of hypolipidaemic drugs.

Journal: Medical toxicology19870101

Title: Hepatic levels of cytosolic, microsomal and 'mitochondrial' epoxide hydrolases and other drug-metabolizing enzymes after treatment of mice with various xenobiotics and endogenous compounds.

Journal: Chemico-biological interactions19870101

Title: Hypolipidemic effect and enhancement of peroxisomal beta-oxidation in the liver of rats by sodium-(E)-3-(4-(3-pyridylmethyl)phenyl)-2-methyl propenoate (OKY-1581), a potent inhibitor of TxA2 synthetase.

Journal: Journal of pharmacobio-dynamics19861201

Title: Distribution and inducibility of cytosolic epoxide hydrolase in male Sprague-Dawley rats.

Journal: Biochemical pharmacology19861001

Title: [Clofibrate hepatitis. A case report].

Journal: Minerva medica19860507

Title: Hepatic foci of cellular and enzymatic alteration and nodules in rats treated with clofibrate or diethylnitrosamine followed by phenobarbital: their rate of onset and their reversibility.

Journal: Journal of the National Cancer Institute19860301

Title: Clofibrate myopathy: a case report and a review of the literature.

Journal: Seminars in arthritis and rheumatism19860201

Title: Hypolipidemic activity of indan-1,3-dione derivatives in rodents.

Journal: Journal of medicinal chemistry19851101

Title: Epoxide metabolism in the liver of mice treated with clofibrate (ethyl-alpha-(p-chlorophenoxyisobutyrate)), a peroxisome proliferator.

Journal: Toxicology and applied pharmacology19850501

Title: Mitochondrial myopathy--a result of clofibrate/etofibrate treatment? Case report.

Journal: Acta neuropathologica19850101

Title: Effects of the hepatocarcinogenic peroxisome-proliferating hypolipidemic agents clofibrate and nafenopin on the rat liver cell membrane enzymes gamma-glutamyltranspeptidase and alkaline phosphatase and on the early stages of liver carcinogenesis.

Journal: Carcinogenesis19841201

Title: Clofibrate-induced muscular syndrome. Case report with ultrastructural findings and review of the literature.

Journal: Israel journal of medical sciences19841101

Title: Factors which may be significant regarding regulation of the clofibrate-dependent induction of hepatic peroxisomal beta-oxidation and hepatomegaly.

Journal: Biochemical pharmacology19840401

Title: Clofibrate-induced myotoxicity in rats. Temporal profile of myopathology.

Journal: European neurology19840101

Title: Clofibrate-induced myocardial injury and disseminated intravascular coagulation in a patient with chronic renal failure.

Journal: Panminerva medica19840101

Title: Cetaben versus clofibrate: comparison of toxicity and peroxisome proliferation in rats.

Journal: Toxicology19831101

Title: Effect of simultaneous administration of clofibrate with diethylnitrosamine on hepatic tumorigenesis in the rat.

Journal: Cancer letters19830501

Title: Carnitine octanoyltransferase of mouse liver peroxisomes: properties and effect of hypolipidemic drugs.

Journal: Archives of biochemistry and biophysics19830401

Title: Peroxisome proliferation in primary cultures of rat hepatocytes.

Journal: Toxicology and applied pharmacology19830101

Title: Effect of bezafibrate on plasma lipids, lipoproteins, apolipoproteins AI, AII and B and LCAT activity in hyperlipidemic, non-insulin-dependent diabetics.

Journal: Atherosclerosis19820601

Title: [Clofibrate therapy--the status quo].

Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete19820115

Title: Effects of various concentrations of ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat.

Journal: Carcinogenesis19820101

Title: [Clofibrate therapy--current status from a gerontological viewpoint].

Journal: Zeitschrift fur Alternsforschung19820101

Title: The consequences of intravenous clofibrate and its implications in the treatment of fat embolism.

Journal: The Journal of trauma19810201

Title: Effect of clofibrate on fatty acid desaturation of rats treated with ethanol.

Journal: Acta physiologica latino americana19810101

Title: Acute renal failure and interstitial nephritis after clofibrate treatment.

Journal: British medical journal19801206

Title: Antiviral activity of antilipidemic compounds on herpes simplex virus type 1.

Journal: Antimicrobial agents and chemotherapy19800801

Title: Clofibrate-induced myopathy in patients with diabetes insipidus.

Journal: Endocrinologia japonica19800601

Title: Hypolipidemic effects of S-methylmethionine (vitamin U) using various experimental procedures.

Journal: Arzneimittel-Forschung19800101

Title: Creatinekinase in hyperlipoproteinemic patients treated with clofibrate.

Journal: Artery19800101

Title: Increase in lipoprotein lipase during clofibrate treatment of hypertriglyceridemia in patients on hemodialysis.

Journal: The New England journal of medicine19791115

Title: [Tolerability and side-effects of bis-(hydroxy-2-ethylthio)-1,10-decane (BS 530) as compared with clofibrate in the therapy of hyperlipemia].

Journal: La Clinica terapeutica19791031

Title: Tumorigenicity of the hypolipidaemic peroxisome proliferator ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) in rats.

Journal: British journal of cancer19790901

Title: Clofibrate-induced muscular syndrome. Report of a case with clinical, electromyographic and pathologic observations.

Journal: Journal of the neurological sciences19790601

Title: Changes in peroxisomes in preneoplastic liver and hepatoma of mice induced by alpha-benzene hexachloride.

Journal: Cancer research19790501

Title: Effect of clofibrate treatment on acylcarnitine oxidation in isolated rat liver mitochondria.

Journal: Medical biology19790201

Title: Myopathy induced by clofibrate treatment in normolipaemic patients.

Journal: Acta paediatrica Academiae Scientiarum Hungaricae19790101

Title: Clofibrate-induced myotonia in the rat.

Journal: Experientia19781215

Title: Myotonia induced with clofibrate in rats.

Journal: Journal of neurology19781025

Title: Enhancement by Wy-14,643, a hepatic peroxisome proliferator, of diethylnitrosamine-initiated hepatic tumorigenesis in the rat.

Journal: British journal of cancer19781001

Title: Possible association of granulomatous hepatitis with clofibrate therapy.

Journal: The New England journal of medicine19780810

Title: Metabolic effects of clofibrate in insulin-dependent ketosis-prone diabetic man.

Journal: Metabolism: clinical and experimental19780401

Title: Increase of the lipoprotein-lipase activity in human skeletal muscle during clofibrate administration.

Journal: European journal of clinical investigation19780401

Title: Renal gluconeogenesis in clofibrate-treated rats.

Journal: The Journal of pharmacology and experimental therapeutics19780301

Title: Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats.

Journal: Atherosclerosis19780301

Title: [Demonstration of the role of cholelithiasis in the onset of acute pancreatitis occurring during clofibrate (or its analog) treatment of atherogenic hyperlipemia].

Journal: Annales de medecine interne19780101

Title: Venous thrombosis, heparin-induced antithrombin III deficiency, and factor VIII.

Journal: Lancet (London, England)19771210

Title: Clofibrate-induced complications in renal disease: a case report.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde19771105

Title: [Drug treatment of hyperlipoproteinemias].

Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete19770501

Title: Clofibrate-induced muscle damage with myoglobinuria and cardiomyopathy.

Journal: The New England journal of medicine19770421

Title: Myokymia, unusual side-effect of clofibrate.

Journal: Lancet (London, England)19761211

Title: Are agents affecting platelet functions clinically useful?

Journal: The American journal of medicine19761201

Title: [Diabetic nephropathy, hypothyroidism and colfibrate-induced myopathy (author's transl)].

Journal: Medizinische Klinik19761112

Title: Clofibrate-induced myopathy and neuropathy.

Journal: Lancet (London, England)19761023

Title: [Studies on the heredity and pathogenesis of familial combined hyperlipidemia ('multiple lipoprotein type' hyperlipidemia)].

Journal: Schweizerische medizinische Wochenschrift19760925

Title: Dextrothyroxine for lowering cholesterol.

Journal: The Medical letter on drugs and therapeutics19760618

Title: Letter: Acute-on-chronic renal failure precipitated by clofibrate.

Journal: Lancet (London, England)19760131

Title: Effect of clofibrate on plasma proteins including components of the hemostatic mechanism.

Journal: Clinica chimica acta; international journal of clinical chemistry19760102

Title: Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure.

Journal: Clinical pharmacokinetics19760101

Title: Clofibrate-induced muscle damage in patients with chronic renal failure.

Journal: Lancet (London, England)19751227

Title: Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones.

Journal: Gastroenterology19751001

Title: Glucagon secretion in primary endogenous hypertriglyceridemia before and after clofibrate treatment.

Journal: Metabolism: clinical and experimental19750801

Title: Effect of halofenate and clofibrate on lipid synthesis in rat adipocytes.

Journal: Biochimica et biophysica acta19750220

Title: Impotence in patients treated with clofibrate.

Journal: Atherosclerosis19750101

Title: Protection against epinephrine induced myocardial necrosis with clofibrate.

Journal: American heart journal19731201

Title: Clofibrate, nephrotic syndrome, and histological changes in muscle.

Journal: Lancet (London, England)19730609

Title: Complications during clofibrate treatment of nephrotic-syndrome hyperlipoproteinaemia.

Journal: Lancet (London, England)19720909

Title: Effects of anti-inflammatory drugs on prostaglandin biosynthesis.

Journal: Nature: New biology19720726

Title: Clofibrate-induced ventricular arrhythmia.

Journal: The American journal of cardiology19690201

Title: Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50.

Title: Chen Y, et al. Clofibrate Attenuates ROS Production by Lipid Overload in Cultured Rat Hepatoma Cells. J Pharm Pharm Sci. 2017;20(0):239-251.

Title: Chen SH, et al. Prenatal PPARα activation by clofibrate increases subcutaneous fat browning in male C57BL/6J mice fed a high-fat diet during adulthood. PLoS One. 2017 Nov 2;12(11):e0187507.

637-07-0 | Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester