[1]DissertationesPharmaceuticae,1957,vol.9,p.205,208 Chem.Abstr.,1958,p.6248
[1]YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1959,vol.79,p.559,564 Chem.Abstr.,1959,p.21662
[1]ActaPoloniaePharmaceutica,1959,vol.16,p.475,477 Chem.Abstr.,1960,p.8693
[1]YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1959,vol.79,p.559,564 Chem.Abstr.,1959,p.21662
[1]AngewandteChemie,1966,vol.78,p.761-769
Title: Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.
Journal: Toxicology and applied pharmacology 20170301
Title: In vitro metabolism of phenytoin in 36 CYP2C9 variants found in the Chinese population.
Journal: Chemico-biological interactions 20160625
Title: Effect of penicillin-based antibiotics, amoxicillin, ampicillin, and piperacillin, on drug-metabolizing activities of human hepatic cytochromes P450.
Journal: The Journal of toxicological sciences 20160201
Title: Identification and Functional Assessment of a New CYP2C9 Allelic Variant CYP2C9*59.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20150801
Title: Effect of Dimethoate on the Activity of Hepatic CYP450 Based on Pharmacokinetics of Probe Drugs.
Journal: Pharmacology 20150101
Title: Identification and characterization of a novel CYP2C9 allelic variant in a warfarin-sensitive patient.
Journal: Pharmacogenomics 20150101
Title: A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101
Title: Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130901
Title: The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: comparison of the N-in-one and single substrate approaches.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130801
Title: Direct and metabolism-dependent cytochrome P450 inhibition assays for evaluating drug-drug interactions.
Journal: Journal of applied toxicology : JAT 20130201
Title: Development and validation of a highly sensitive LC-MS/MS-ESI method for the determination of bicalutamide in mouse plasma: application to a pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20121201
Title: SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells.
Journal: American journal of physiology. Endocrinology and metabolism 20121101
Title: Insulin reduces excitation in gastric-related neurons of the dorsal motor nucleus of the vagus.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20121015
Title: cAMP-mediated and metabolic amplification of insulin secretion are distinct pathways sharing independence of β-cell microfilaments.
Journal: Endocrinology 20121001
Title: Triphenyltin impairs insulin secretion by decreasing glucose-induced NADP(H) and ATP production in hamster pancreatic β-cells.
Journal: Toxicology 20120928
Title: Enzyme kinetic and molecular docking studies on the metabolic interactions of 1-hydroxy-2,3,5-trimethoxy-xanthone, isolated from Halenia elliptica D. Don, with model probe substrates of human cytochrome P450 enzymes.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120915
Title: A novel relay method for determining low-clearance values.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120901
Title: Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction.
Journal: Journal of hepatology 20120901
Title: Deficiency of proton-sensing ovarian cancer G protein-coupled receptor 1 attenuates glucose-stimulated insulin secretion.
Journal: Endocrinology 20120901
Title: Synthesis, antidiabetic and hypolipidemic activities of new diethylamine and triethoxysilyl derivatives of tolbutamide on rats.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20120901
Title: Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour.
Journal: Diabetologia 20120901
Title: Distribution of CYP2C9*13 allele in the Chinese Han and the long-range haplotype containing CYP2C9*13 and CYP2C19*2.
Journal: Biopharmaceutics & drug disposition 20120901
Title: Proteome profiling of tolbutamide-treated rat primary hepatocytes using nano LC-MS/MS and label-free protein quantitation.
Journal: Electrophoresis 20120901
Title: Metabotropic actions of the volatile anaesthetic sevoflurane increase protein kinase M synthesis and induce immediate preconditioning protection of rat hippocampal slices.
Journal: The Journal of physiology 20120815
Title: Studying significance of apoptosis in mediating tolbutamide-induced teratogenesis in vitro.
Journal: Fundamental & clinical pharmacology 20120801
Title: Cocktail approach for in vivo phenotyping of 5 major CYP450 isoenzymes: development of an effective sampling, extraction, and analytical procedure and pilot study with comparative genotyping.
Journal: Journal of clinical pharmacology 20120801
Title: Effects of Panax notoginseng saponins on the activities of CYP1A2, CYP2C9, CYP2D6 and CYP3A4 in rats in vivo.
Journal: Phytotherapy research : PTR 20120801
Title: Effect of P450 oxidoreductase variants on the metabolism of model substrates mediated by CYP2C9.1, CYP2C9.2, and CYP2C9.3.
Journal: Pharmacogenetics and genomics 20120801
Title: Down-regulation of hepatic CYP3A and CYP2C mediated metabolism in rats with moderate chronic kidney disease.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120801
Title: Ca(2+)-dependent desensitization of insulin secretion by strong potassium depolarization.
Journal: American journal of physiology. Endocrinology and metabolism 20120715
Title: Delta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin.
Journal: Diabetologia 20120701
Title: Centrifugal air-assisted melt agglomeration for fast-release 'granulet' design.
Journal: International journal of pharmaceutics 20120701
Title: Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats.
Journal: Journal of ethnopharmacology 20120626
Title: The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine.
Journal: The Journal of physiology 20120615
Title: Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis.
Journal: Magnetic resonance in medicine 20120601
Title: Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
Journal: Molecular biology reports 20120601
Title: Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues.
Journal: Bioorganic & medicinal chemistry letters 20120601
Title: Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Journal: Journal of medicinal chemistry 20120524
Title: Improvac does not modify the expression and activities of the major drug metabolizing enzymes cytochrome P450 3A and 2C in pigs.
Journal: Vaccine 20120521
Title: Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells.
Journal: American journal of physiology. Endocrinology and metabolism 20120515
Title: Gliclazide may have an antiapoptotic effect related to its antioxidant properties in human normal and cancer cells.
Journal: Molecular biology reports 20120501
Title: Effect of Ginkgo biloba special extract EGb 761® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers.
Journal: European journal of clinical pharmacology 20120501
Title: Verapamil does not modify catalytic activity of CYP450 in rainbow trout after long-term exposure.
Journal: Ecotoxicology and environmental safety 20120501
Title: In vitro modulatory effects of flavonoids on human cytochrome P450 2C8 (CYP2C8).
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120501
Title: Polysaccharide isolated from Triticum aestivum stimulates insulin release from pancreatic cells via the ATP-sensitive K+ channel.
Journal: International journal of molecular medicine 20120501
Title: Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies.
Journal: European journal of epidemiology 20120501
Title: Predicting drug candidate victims of drug-drug interactions, using microdosing.
Journal: Clinical pharmacokinetics 20120401
Title: Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes.
Journal: Pharmacotherapy 20120401
Title: Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120319
Title: On potential interactions between non-selective cation channel TRPM4 and sulfonylurea receptor SUR1.
Journal: The Journal of biological chemistry 20120316
Title: Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell.
Journal: Molecular and cellular endocrinology 20120305
Title: Serum deprivation induces glucose response and intercellular coupling in human pancreatic adenocarcinoma PANC-1 cells.
Journal: Pancreas 20120301
Title: Differential contribution of TM6 and TM12 to the pore of CFTR identified by three sulfonylurea-based blockers.
Journal: Pflugers Archiv : European journal of physiology 20120301
Title: Regulation of calcium in pancreatic α- and β-cells in health and disease.
Journal: Cell calcium 20120301
Title: Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A.
Journal: Pharmacogenetics and genomics 20120301
Title: Antihyperglycemic effects of the methanol leaf extract of Diaphananthe bidens in normoglycemic and streptozotocin-induced hyperglycemic rats.
Journal: Asian Pacific journal of tropical medicine 20120301
Title: Effects of Ougan juice on P450 activities using a cocktail method.
Journal: Die Pharmazie 20120301
Title: Relationships between serum adiponectin and soluble TNF-α receptors and glucose and lipid oxidation in lean and obese subjects.
Journal: Acta diabetologica 20120201
Title: Ethanol causes endoplasmic reticulum stress and impairment of insulin secretion in pancreatic β-cells.
Journal: Alcohol (Fayetteville, N.Y.) 20120201
Title: Dual microfluidic perifusion networks for concurrent islet perifusion and optical imaging.
Journal: Biomedical microdevices 20120201
Title: In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.
Journal: Pharmaceutical research 20120201
Title: Variations in tissue selectivity amongst insulin secretagogues: a systematic review.
Journal: Diabetes, obesity & metabolism 20120201
Title: Structural nucleotide analogs are potent activators/inhibitors of pancreatic β cell KATP channels: an emerging mechanism supporting their use as antidiabetic drugs.
Journal: The Journal of pharmacology and experimental therapeutics 20120201
Title: Administration of insulin to newly hatched chicks improves growth performance via impairment of MyoD gene expression and enhancement of cell proliferation in chicken myoblasts.
Journal: General and comparative endocrinology 20120201
Title: Epac2: a sulfonylurea receptor?
Journal: Biochemical Society transactions 20120201
Title: Evaluation of impact of Herba Erigerontis injection, a Chinese herbal prescription, on rat hepatic cytochrome P450 enzymes by cocktail probe drugs.
Journal: Journal of ethnopharmacology 20120106
Title: Role of viscosity in influencing the glass-forming ability of organic molecules from the undercooled melt state.
Journal: Pharmaceutical research 20120101
Title: Small conductance potassium channels drive ATP-activated chloride secretion in the oviduct.
Journal: American journal of physiology. Cell physiology 20120101
Title: Hypolipidemic Activity of Eryngium carlinae on Streptozotocin-Induced Diabetic Rats.
Journal: Biochemistry research international 20120101
Title: Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells.
Journal: PloS one 20120101
Title: Preventive pharmacotherapy in type 2 diabetes mellitus.
Journal: Indian journal of endocrinology and metabolism 20120101
Title: The metabolic syndrome in Africa: Current trends.
Journal: Indian journal of endocrinology and metabolism 20120101
Title: Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in db/db mice.
Journal: Nutrition & metabolism 20120101
Title: Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats.
Journal: Indian journal of pharmacology 20120101
Title: Evaluation of the effects of glimepiride (Amaryl) and repaglinide (novoNorm) on atherosclerosis progression in high cholesterol-fed male rabbits.
Journal: Journal of cardiovascular disease research 20120101
Title: A pharmacological appraisal of medicinal plants with antidiabetic potential.
Journal: Journal of pharmacy & bioallied sciences 20120101
Title: In vitro phenotypic, genomic and proteomic characterization of a cytokine-resistant murine β-TC3 cell line.
Journal: PloS one 20120101
Title: Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Insulinotropic effect of the non-steroidal compound STX in pancreatic β-cells.
Journal: PloS one 20120101
Title: Deregulation of CREB signaling pathway induced by chronic hyperglycemia downregulates NeuroD transcription.
Journal: PloS one 20120101
Title: An overview of the evidence and mechanisms of herb-drug interactions.
Journal: Frontiers in pharmacology 20120101
Title: Efficacy of various antidiabetic agents as add-on treatments to metformin in type 2 diabetes mellitus: systematic review and meta-analysis.
Journal: ISRN endocrinology 20120101
Title: Priapism, pomegranate juice, and sildenafil: Is there a connection?
Journal: Urology annals 20120101
Title: The exaptation of endocrine pharmacology.
Journal: Indian journal of endocrinology and metabolism 20120101
Title: The management of type 2 diabetic patients with hypoglycaemic agents.
Journal: ISRN endocrinology 20120101
Title: Suppression of the nuclear factor Eny2 increases insulin secretion in poorly functioning INS-1E insulinoma cells.
Journal: Experimental diabetes research 20120101
Title: Interaction of virstatin with human serum albumin: spectroscopic analysis and molecular modeling.
Journal: PloS one 20120101
Title: Functional herbal food ingredients used in type 2 diabetes mellitus.
Journal: Pharmacognosy reviews 20120101
Title: Pharmacological approaches to the management of type 2 diabetes in fasting adults during Ramadan.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20120101
Title: Critical evaluation of the efficacy and tolerability of azilsartan.
Journal: Vascular health and risk management 20120101
Title: A comprehensive review of the pharmacodynamics, pharmacokinetics, and clinical effects of the neutral endopeptidase inhibitor racecadotril.
Journal: Frontiers in pharmacology 20120101
Title: Towards therapeutic applications of arthropod venom k(+)-channel blockers in CNS neurologic diseases involving memory acquisition and storage.
Journal: Journal of toxicology 20120101
Title: Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Calcium-sensing receptor activation increases cell-cell adhesion and β-cell function.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Inhibitory effects of kale ingestion on metabolism by cytochrome P450 enzymes in rats.
Journal: Biomedical research (Tokyo, Japan) 20120101
Title: Hypoglycemic Activity of Aqueous Extracts from Catharanthus roseus.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20111201
Title: Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat.
Journal: Journal of neurophysiology 20111201
Title: Rapid functional evaluation of beta-cells by extracellular recording of membrane potential oscillations with microelectrode arrays.
Journal: Pflugers Archiv : European journal of physiology 20111201
Title: Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice.
Journal: Diabetes 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Involvement of ATP-sensitive potassium (K(ATP)) channels in the loss of beta-cell function induced by human islet amyloid polypeptide.
Journal: The Journal of biological chemistry 20111125
Title: Exendin-4 upregulates the expression of Wnt-4, a novel regulator of pancreatic β-cell proliferation.
Journal: American journal of physiology. Endocrinology and metabolism 20111101
Title: Ameliorative effect of Aegle marmelos leaf extract on early stage alloxan-induced diabetic cardiomyopathy in rats.
Journal: Pharmaceutical biology 20111101
Title: Polysaccharide peptides from Coriolus versicolor competitively inhibit tolbutamide 4-hydroxylation in specific human CYP2C9 isoform and pooled human liver microsomes.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20111015
Title: In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.
Journal: The Journal of clinical investigation 20111003
Title: Identification of the human liver cytochrome P450 isoenzymes responsible for the 5-methylhydroxylation of the novel anti-fibrotic drug AKF-PD.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20111001
Title: Preparation of human drug metabolites using fungal peroxygenases.
Journal: Biochemical pharmacology 20111001
Title: Comparable long-term mortality risk associated with individual sulfonylureas in diabetes patients with heart failure.
Journal: Diabetes research and clinical practice 20111001
Title: The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition.
Journal: Diabetes & metabolism journal 20111001
Title: Alterations of colonic contractility in long-term diabetic rat model.
Journal: Journal of neurogastroenterology and motility 20111001
Title: Hypoglycemic activity of alkaloidal fraction of Tinospora cordifolia.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110915
Title: Type 2 diabetes quality of life patients treated with insulin and oral hypoglycemic medication.
Journal: Acta diabetologica 20110901
Title: Comprehensive quantitative and qualitative liquid chromatography-radioisotope-mass spectrometry analysis for safety testing of tolbutamide metabolites without standard samples.
Journal: Journal of pharmaceutical sciences 20110901
Title: Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice.
Journal: Journal of lipid research 20110901
Title: Cholesterol elevation impairs glucose-stimulated Ca(2+) signaling in mouse pancreatic β-cells.
Journal: Endocrinology 20110901
Title: Remodeling of atrial ATP-sensitive K⁺ channels in a model of salt-induced elevated blood pressure.
Journal: American journal of physiology. Heart and circulatory physiology 20110901
Title: Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors.
Journal: Biopharmaceutics & drug disposition 20110901
Title: Effects of Ginkgo biloba extract on the pharmacokinetics and pharmacodynamics of tolbutamide in protein-restricted rats.
Journal: The Journal of pharmacy and pharmacology 20110901
Title: Lower expression of PKAα impairs insulin secretion in islets isolated from low-density lipoprotein receptor (LDLR(-/-)) knockout mice.
Journal: Metabolism: clinical and experimental 20110801
Title: Mortality and cardiovascular risk associated with different insulin secretagogues compared with metformin in type 2 diabetes, with or without a previous myocardial infarction: a nationwide study.
Journal: European heart journal 20110801
Title: In vitro inhibitory effects of Wen-pi-tang-Hab-Wu-ling-san on human cytochrome P450 isoforms.
Journal: Journal of clinical pharmacy and therapeutics 20110801
Title: Structure and dynamics of the membrane-bound cytochrome P450 2C9.
Journal: PLoS computational biology 20110801
Title: Effects of Sulfonylureas on Peroxisome Proliferator-Activated Receptor γ Activity and on Glucose Uptake by Thiazolidinediones.
Journal: Diabetes & metabolism journal 20110801
Title: Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells.
Journal: The Journal of biological chemistry 20110722
Title: From caffeine to fish waste: amine compounds present in food and drugs and their interactions with primary amine oxidase.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20110701
Title: Blockade of the antinociception induced by diclofenac, but not of indomethacin, by sulfonylureas and biguanides.
Journal: Pharmacology, biochemistry, and behavior 20110701
Title: High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.
Journal: Nature neuroscience 20110701
Title: Glucosensing in parvocellular neurons of the rat hypothalamic paraventricular nucleus.
Journal: The European journal of neuroscience 20110701
Title: The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.
Journal: Journal of enzyme inhibition and medicinal chemistry 20110601
Title: Effects of multiple-dose pegylated interferon alfa-2b on the activity of drug-metabolizing enzymes in persons with chronic hepatitis C.
Journal: European journal of clinical pharmacology 20110601
Title: Development and validation of a LC-MS/MS method based on a new 96-well Hybrid-SPE™-precipitation technique for quantification of CYP450 substrates/metabolites in rat plasma.
Journal: Analytical and bioanalytical chemistry 20110601
Title: Regional distribution of drug-metabolizing enzyme activities in the liver and small intestine of cynomolgus monkeys.
Journal: Drug metabolism and pharmacokinetics 20110601
Title: High-throughput and simultaneous analysis of eight central-acting muscle relaxants in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry in the positive and negative ionization modes.
Journal: Analytical and bioanalytical chemistry 20110601
Title: Mutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetes.
Journal: Diabetes 20110601
Title: Oral hypoglycaemic, antihyperglycaemic and antidiabetic activities of Sri Lankan Broken Orange Pekoe Fannings (BOPF) grade black tea (Camellia sinensis L.) in rats.
Journal: Journal of ethnopharmacology 20110517
Title: Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes.
Journal: Biotechnology journal 20110501
Title: Glucosensing by GnRH neurons: inhibition by androgens and involvement of AMP-activated protein kinase.
Journal: Molecular endocrinology (Baltimore, Md.) 20110501
Title: Effects of brucine combined with glycyrrhetinic acid or liquiritin on rat hepatic cytochrome P450 activities in vivo.
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110501
Title: Use of peak decay analysis and affinity microcolumns containing silica monoliths for rapid determination of drug-protein dissociation rates.
Journal: Journal of chromatography. A 20110415
Title: A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening.
Journal: International journal of pharmaceutics 20110415
Title: Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line.
Journal: Biochemical and biophysical research communications 20110415
Title: Diabetes treatment and cardiovascular safety.
Journal: Diabetes care 20110401
Title: Resveratrol-activated SIRT1 in liver and pancreatic β-cells: a Janus head looking to the same direction of metabolic homeostasis.
Journal: Aging 20110401
Title: A dual action of saturated fatty acids on electrical activity in rat pancreatic β-cells. Role of volume-regulated anion channel and KATP channel currents.
Journal: The Journal of physiology 20110315
Title: An aqueous extract of Curcuma longa (turmeric) rhizomes stimulates insulin release and mimics insulin action on tissues involved in glucose homeostasis in vitro.
Journal: Phytotherapy research : PTR 20110301
Title: Evaluation of the efficacy and tolerability of miglitol in Chinese patients with type 2 diabetes mellitus inadequately controlled by diet and sulfonylureas.
Journal: Acta diabetologica 20110301
Title: Metabolic amplification of insulin secretion by glucose is independent of β-cell microtubules.
Journal: American journal of physiology. Cell physiology 20110301
Title: Inhibition of gastric motility by hyperglycemia is mediated by nodose ganglia KATP channels.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20110301
Title: Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats.
Journal: Diabetes 20110301
Title: Protection of pancreatic INS-1 β-cells from glucose- and fructose-induced cell death by inhibiting mitochondrial permeability transition with cyclosporin A or metformin.
Journal: Cell death & disease 20110301
Title: Induction of insulin secretion by an aqueous extract of Tabernanhte iboga Baill. (Apocynaceae) in rat pancreatic islets of Langerhans.
Journal: Journal of ethnopharmacology 20110216
Title: Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.
Journal: The Journal of biological chemistry 20110211
Title: Recognition of sulfonylurea receptor (ABCC8/9) ligands by the multidrug resistance transporter P-glycoprotein (ABCB1): functional similarities based on common structural features between two multispecific ABC proteins.
Journal: The Journal of biological chemistry 20110204
Title: Comparison of intrinsic clearances in human liver microsomes and suspended hepatocytes from the same donor livers: clearance-dependent relationship and implications for prediction of in vivo clearance.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110201
Title: Exchange protein directly activated by cyclic AMP isoform 2 is not a direct target of sulfonylurea drugs.
Journal: Assay and drug development technologies 20110201
Title: Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice.
Journal: Diabetes 20110201
Title: A newly identified CG301269 improves lipid and glucose metabolism without body weight gain through activation of peroxisome proliferator-activated receptor alpha and gamma.
Journal: Diabetes 20110201
Title: Relationship between gamma-glutamyl transferase and glucose intolerance in first degree relatives of type 2 diabetics patients.
Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110201
Title: Binding of tolbutamide to glycated human serum albumin.
Journal: Journal of pharmaceutical and biomedical analysis 20110125
Title: Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice.
Journal: Diabetes 20110101
Title: Congenital hyperinsulinism and glucose hypersensitivity in homozygous and heterozygous carriers of Kir6.2 (KCNJ11) mutation V290M mutation: K(ATP) channel inactivation mechanism and clinical management.
Journal: Diabetes 20110101
Title: Clinical drugs undergoing polymorphic metabolism by human cytochrome P450 2C9 and the implication in drug development.
Journal: Current medicinal chemistry 20110101
Title: TRP-ing down the path to insulin secretion.
Journal: Diabetes 20110101
Title: An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.
Journal: Drug metabolism letters 20110101
Title: Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey.
Journal: PloS one 20110101
Title: Evaluating compliance to a low glycaemic index (GI) diet in women with polycystic ovary syndrome (PCOS).
Journal: BMC research notes 20110101
Title: Sex differences in drug disposition.
Journal: Journal of biomedicine & biotechnology 20110101
Title: Cardiovascular safety of exenatide BID: an integrated analysis from controlled clinical trials in participants with type 2 diabetes.
Journal: Cardiovascular diabetology 20110101
Title: Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.
Journal: Genome biology 20110101
Title: Mucoadhesive drug delivery systems.
Journal: Journal of pharmacy & bioallied sciences 20110101
Title: Effects of zinc and multimineral vitamin supplementation on glycemic and lipid control in adult diabetes.
Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Title: Glycated albumin suppresses glucose-induced insulin secretion by impairing glucose metabolism in rat pancreatic β-cells.
Journal: Nutrition & metabolism 20110101
Title: Nateglinide stimulates glucagon-like peptide-1 release by human intestinal L cells via a K(ATP) channel-independent mechanism.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Pharmacokinetics of tolbutamide in acute renal failure induced by glycerol: speculative thoughts and perspectives.
Journal: Drug metabolism and pharmacokinetics 20110101
Title: [Dissolution characteristics of composite particles using a spray freeze drying].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
Title: Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome.
Journal: BMC medical genomics 20110101
Title: Dose study of the multikinase inhibitor, LY2457546, in patients with relapsed acute myeloid leukemia to assess safety, pharmacokinetics, and pharmacodynamics.
Journal: Cancer management and research 20110101
Title: A local glucose-and oxygen concentration-based insulin secretion model for pancreatic islets.
Journal: Theoretical biology & medical modelling 20110101
Title: Chronopharmacological assessment identified GLUT4 as a factor responsible for the circadian variation of the hypoglycemic effect of tolbutamide in rats.
Journal: Drug metabolism and pharmacokinetics 20110101
Title: Evaluation of antidiabetic and related actions of some Indian medicinal plants in diabetic rats.
Journal: Asian Pacific journal of tropical medicine 20110101
Title: Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials.
Journal: BMJ (Clinical research ed.) 20110101
Title: Evaluation of CYP450 inhibitory effects and steady-state pharmacokinetics of genistein in combination with cholecalciferol and citrated zinc bisglycinate in postmenopausal women.
Journal: International journal of women's health 20110101
Title: Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance.
Journal: Clinical proteomics 20110101
Title: Control of the intracellular redox state by glucose participates in the insulin secretion mechanism.
Journal: PloS one 20110101
Title: Serum insulin-like growth factor-I in diabetic retinopathy.
Journal: Molecular vision 20110101
Title: Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population.
Journal: PloS one 20110101
Title: Prevalence and risk factors of diabetes and impaired fasting glucose in Nauru.
Journal: BMC public health 20110101
Title: Long-term use and tolerability of irbesartan for control of hypertension.
Journal: Integrated blood pressure control 20110101
Title: Medicinal chemistry of the anti-diabetic effects of momordica charantia: active constituents and modes of actions.
Journal: The open medicinal chemistry journal 20110101
Title: HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4.
Journal: PloS one 20110101
Title: Early markers of glycaemic control in children with type 1 diabetes mellitus.
Journal: PloS one 20110101
Title: Attenuation of nonenzymatic glycation, hyperglycemia, and hyperlipidemia in streptozotocin-induced diabetic rats by chloroform leaf extract of Azadirachta indica.
Journal: Pharmacognosy magazine 20110101
Title: Functional evaluation of genetic and environmental regulators of p450 mRNA levels.
Journal: PloS one 20110101
Title: Molecular imaging: a promising tool to monitor islet transplantation.
Journal: Journal of transplantation 20110101
Title: Measurement of warfarin in the oral fluid of patients undergoing anticoagulant oral therapy.
Journal: PloS one 20110101
Title: Alternative therapies useful in the management of diabetes: A systematic review.
Journal: Journal of pharmacy & bioallied sciences 20110101
Title: Increased glutathione synthesis following Nrf2 activation by vanadyl sulfate in human chang liver cells.
Journal: International journal of molecular sciences 20110101
Title: Investigations on Piper betle grown in Sri Lanka.
Journal: Pharmacognosy reviews 20110101
Title: Extended hildebrand solubility approach: satranidazole in mixtures of dioxane and water.
Journal: Indian journal of pharmaceutical sciences 20110101
Title: Polymorphisms of human cytochrome P450 2C9 and the functional relevance.
Journal: Toxicology 20101205
Title: Effect of HLA class I and class II alleles on progression from autoantibody positivity to overt type 1 diabetes in children with risk-associated class II genotypes.
Journal: Diabetes 20101201
Title: High levels of serum prolactin protect against diabetic retinopathy by increasing ocular vasoinhibins.
Journal: Diabetes 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.
Journal: European journal of endocrinology 20101201
Title: Physiologic characterization of type 2 diabetes-related loci.
Journal: Current diabetes reports 20101201
Title: Effects of metformin on BRIN-BD11 beta-cell insulin secretory desensitization induced by prolonged exposure to sulphonylureas.
Journal: Diabetes, obesity & metabolism 20101201
Title: Drug structure-transport relationships.
Journal: Journal of pharmacokinetics and pharmacodynamics 20101201
Title: Influence of hepatic impairment on pharmacokinetics of the human GLP-1 analogue, liraglutide.
Journal: British journal of clinical pharmacology 20101201
Title: Hypoglycemic effect of methanolic extract of Anacardium occidentale leaves in alloxan-induced diabetic rats.
Journal: Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20101125
Title: Chromatographic studies of changes in binding of sulfonylurea drugs to human serum albumin due to glycation and fatty acids.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101115
Title: Inhibition of ATP-sensitive potassium channels increases HSV-tk/GCV bystander effect in U373 human glioma cells by enhancing gap junctional intercellular communication.
Journal: Neuropharmacology 20101101
Title: Mitochondrial matrix pH controls oxidative phosphorylation and metabolism-secretion coupling in INS-1E clonal beta cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101101
Title: Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy.
Journal: Diabetes 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Journal: Bioorganic & medicinal chemistry 20101101
Title: Anti-hyperglycemic compound (GII) from fenugreek (Trigonella foenum-graecum Linn.) seeds, its purification and effect in diabetes mellitus.
Journal: Indian journal of experimental biology 20101101
Title: Antidiabetic effect of some medicinal plants of Oriental Morocco in neonatal non-insulin-dependent diabetes mellitus rats.
Journal: Human & experimental toxicology 20101001
Title: Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells.
Journal: Diabetes 20101001
Title: Drug binding to Sudlow's site I impairs allosterically human serum heme-albumin-catalyzed peroxynitrite detoxification.
Journal: IUBMB life 20101001
Title: Anti-Oxidative Effect of Cassia auriculata on Streptozotocin Induced Diabetic Rats.
Journal: Indian journal of clinical biochemistry : IJCB 20101001
Title: Functional expression of large-conductance Ca2+-activated potassium channels in lateral globus pallidus neurons.
Journal: Neuroscience 20100915
Title: Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.
Journal: The Journal of physiology 20100915
Title: Metabolite formation kinetics and intrinsic clearance of phenacetin, tolbutamide, alprazolam, and midazolam in adenoviral cytochrome P450-transfected HepG2 cells and comparison with hepatocytes and in vivo.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901
Title: Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.
Journal: Diabetes 20100901
Title: In vivo Studies on Antidiabetic Plants Used in South African Herbal Medicine.
Journal: Journal of clinical biochemistry and nutrition 20100901
Title: Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans.
Journal: Rapid communications in mass spectrometry : RCM 20100830
Title: Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate.
Journal: Journal of pharmaceutical and biomedical analysis 20100801
Title: Metabolic amplifying pathway increases both phases of insulin secretion independently of beta-cell actin microfilaments.
Journal: American journal of physiology. Cell physiology 20100801
Title: Counterpoint: postprandial glucose levels are not a clinically important treatment target.
Journal: Diabetes care 20100801
Title: Evaluation of Cassia occidentalis for in vitro cytotoxicity against human cancer cell lines and antibacterial activity.
Journal: Indian journal of pharmacology 20100801
Title: Rifampicin-induced thrombocytopenia.
Journal: Indian journal of pharmacology 20100801
Title: AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets.
Journal: Molecular and cellular endocrinology 20100729
Title: In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.
Journal: Journal of ethnopharmacology 20100720
Title: A protein-coated magnetic beads as a tool for the rapid drug-protein binding study.
Journal: Journal of pharmaceutical and biomedical analysis 20100708
Title: Conformational polymorphism of tolbutamide: A structural, spectroscopic, and thermodynamic characterization of Burger's forms I-IV.
Journal: Journal of pharmaceutical sciences 20100701
Title: Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis.
Journal: Diabetologia 20100701
Title: Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.
Journal: Diabetes 20100701
Title: Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.
Journal: Diabetes 20100701
Title: 2009 World Congress on the Insulin Resistance Syndrome: cardiovascular disease concepts.
Journal: Diabetes care 20100701
Title: Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.
Journal: The Journal of pharmacy and pharmacology 20100701
Title: Pancreatic beta-cell signaling: toward better understanding of diabetes and its treatment.
Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100611
Title: Peptide YY is critical for acylethanolamine receptor Gpr119-induced activation of gastrointestinal mucosal responses.
Journal: Cell metabolism 20100609
Title: Prevalence and correlates of inadequate glycaemic control: results from a nationwide survey in 6,671 adults with diabetes in Brazil.
Journal: Acta diabetologica 20100601
Title: The risk of overall mortality in patients with type 2 diabetes receiving glipizide, glyburide, or glimepiride monotherapy: a retrospective analysis.
Journal: Diabetes care 20100601
Title: LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.
Journal: American journal of physiology. Endocrinology and metabolism 20100601
Title: Characterization of the binding of sulfonylurea drugs to HSA by high-performance affinity chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601
Title: Neuropathy, retinopathy, and glucose-lowering treatments.
Journal: Diabetes care 20100601
Title: Hypolipidaemic & hepatoprotective effects of Psidium guajava raw fruit peel in experimental diabetes.
Journal: The Indian journal of medical research 20100601
Title: Immediate but not long-term administration of nicardipine inhibits tolbutamide-induced insulin secretion from rat pancreatic beta cells.
Journal: Pancreas 20100501
Title: Effects of nicorandil on sympathetic neurotransmission in rat caudal artery.
Journal: Clinical and experimental pharmacology & physiology 20100501
Title: Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles.
Journal: Diabetes 20100501
Title: Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS--a high throughput approach to evaluate drug-drug interactions.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100501
Title: Change in tolbutamide permeability in rat jejunum and Caco-2 cells by Sho-saiko-to (Xiao Chai Hu Tang), a Chinese traditional medicine.
Journal: The Journal of pharmacy and pharmacology 20100501
Title: Effects of several pyrethroids on hepatic cytochrome P450 activities in rats.
Journal: The Journal of veterinary medical science 20100401
Title: Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.
Journal: Journal of neurochemistry 20100401
Title: CYP2C9 genotype does not affect risk of tobacco-related cancer in the general population.
Journal: Cancer epidemiology 20100401
Title: Blockade of presynaptic K ATP channels reduces the zinc-mediated posttetanic depression at hippocampal mossy fiber synapses.
Journal: Brain research 20100312
Title: Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100301
Title: Six months of diazoxide treatment at bedtime in newly diagnosed subjects with type 1 diabetes does not influence parameters of {beta}-cell function and autoimmunity but improves glycemic control.
Journal: Diabetes care 20100301
Title: Studies of the toxicological potential of capsinoids, XIII: inhibitory effects of capsaicin and capsinoids on cytochrome P450 3A4 in human liver microsomes.
Journal: International journal of toxicology 20100301
Title: Facilitation of ß-cell K(ATP) channel sulfonylurea sensitivity by a cAMP analog selective for the cAMP-regulated guanine nucleotide exchange factor Epac.
Journal: Islets 20100301
Title: Electrophysiological identification of glucose-sensing neurons in rat nodose ganglia.
Journal: The Journal of physiology 20100215
Title: Gap junctions and memory: an investigation using a single trial discrimination avoidance task for the neonate chick.
Journal: Neurobiology of learning and memory 20100201
Title: Pregnancy restores insulin secretion from pancreatic islets in cafeteria diet-induced obese rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100201
Title: Predictive performance for population models using stochastic differential equations applied on data from an oral glucose tolerance test.
Journal: Journal of pharmacokinetics and pharmacodynamics 20100201
Title: Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channels.
Journal: British journal of pharmacology 20100201
Title: 2-hydroxy 4-methoxy benzoic acid isolated from roots of Hemidesmus indicus ameliorates liver, kidney and pancreas injury due to streptozotocin-induced diabetes in rats.
Journal: Indian journal of experimental biology 20100201
Title: Na, K-ATPase: Ubiquitous Multifunctional Transmembrane Protein and its Relevance to Various Pathophysiological Conditions.
Journal: Journal of clinical medicine research 20100201
Title: High performance liquid chromatography determination of cytochrome P450 1A and 2C activities in bovine liver microsomes.
Journal: Veterinary journal (London, England : 1997) 20100101
Title: Terminalia bellirica stimulates the secretion and action of insulin and inhibits starch digestion and protein glycation in vitro.
Journal: The British journal of nutrition 20100101
Title: ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.
Journal: Diabetes 20100101
Title: Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets.
Journal: Endocrinology 20100101
Title: Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Journal: Bioorganic & medicinal chemistry letters 20100101
Title: Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract.
Journal: Nutrition & metabolism 20100101
Title: Development of an LC-MS method for measuring TNF in human vaginal tissue.
Journal: Journal of chromatographic science 20100101
Title: Assessment of efficacy and tolerability of once-daily extended release metformin in patients with type 2 diabetes mellitus.
Journal: Diabetology & metabolic syndrome 20100101
Title: Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test.
Journal: Theoretical biology & medical modelling 20100101
Title: Efficient gene delivery and silencing of mouse and human pancreatic islets.
Journal: BMC biotechnology 20100101
Title: Liraglutide in the treatment of type 2 diabetes mellitus: clinical utility and patient perspectives.
Journal: Patient preference and adherence 20100101
Title: Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women.
Journal: Nutrition & metabolism 20100101
Title: Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures.
Journal: Therapeutics and clinical risk management 20100101
Title: Diazoxide promotes oligodendrocyte precursor cell proliferation and myelination.
Journal: PloS one 20100101
Title: Differentiation of human multipotent dermal fibroblasts into islet-like cell clusters.
Journal: BMC cell biology 20100101
Title: Transgenic overexpression of active calcineurin in beta-cells results in decreased beta-cell mass and hyperglycemia.
Journal: PloS one 20100101
Title: Effect of the insulin plant (Costus igneus) leaves on dexamethasone-induced hyperglycemia.
Journal: International journal of Ayurveda research 20100101
Title: Bench-to-bedside review: Molecular pharmacology and clinical use of inert gases in anesthesia and neuroprotection.
Journal: Critical care (London, England) 20100101
Title: A systems biology approach to identify effective cocktail drugs.
Journal: BMC systems biology 20100101
Title: Effects of oral glucose-lowering drugs on long term outcomes in patients with diabetes mellitus following myocardial infarction not treated with emergent percutaneous coronary intervention--a retrospective nationwide cohort study.
Journal: Cardiovascular diabetology 20100101
Title: Exenatide once weekly: clinical outcomes and patient satisfaction.
Journal: Patient preference and adherence 20100101
Title: Disease progression and search for monogenic diabetes among children with new onset type 1 diabetes negative for ICA, GAD- and IA-2 Antibodies.
Journal: BMC endocrine disorders 20100101
Title: Pharmacotherapy-Based Problems in the Management of Diabetes Mellitus: Needs Much More to be Done!
Journal: Journal of young pharmacists : JYP 20100101
Title: Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies.
Journal: Vascular health and risk management 20100101
Title: Cytokines in the Progression of Pancreatic β-Cell Dysfunction.
Journal: International journal of endocrinology 20100101
Title: ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies.
Journal: Particle and fibre toxicology 20100101
Title: Update on treatment of partial onset epilepsy: role of eslicarbazepine.
Journal: Neuropsychiatric disease and treatment 20100101
Title: Evaluation of the Hypoglycemic Activity of Cucumis metuliferus (Cucurbitaceae) Fruit Pulp Extract in Normoglycemic and Alloxan-Induced Hyperglycemic Rats.
Journal: Journal of young pharmacists : JYP 20100101
Title: A study on drug-drug interaction of esomeprazole and anti-diabetic drugs.
Journal: Journal of young pharmacists : JYP 20100101
Title: Pertussis toxin nullifies the depolarization of the membrane potential and the stimulation of the rapid phase of Ca entry through L-type calcium channels that are produced by follicle stimulating hormone in 10- to 12-day-old rat Sertoli cells.
Journal: Frontiers in physiology 20100101
Title: Preparation and characterization of microparticles of piroxicam by spray drying and spray chilling methods.
Journal: Research in pharmaceutical sciences 20100101
Title: Glargine and detemir: Safety and efficacy profiles of the long-acting basal insulin analogs.
Journal: Drug, healthcare and patient safety 20100101
Title: Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats.
Journal: Pharmacognosy research 20100101
Title: Protective role of glibenclamide against nicotinamide-streptozotocin induced nuclear damage in diabetic Wistar rats.
Journal: Journal of pharmacology & pharmacotherapeutics 20100101
Title: Cyclodextrins in delivery systems: Applications.
Journal: Journal of pharmacy & bioallied sciences 20100101
Title: Double-blind, placebo-controlled clinical evaluation of an Ayurvedic formulation (GlucoCare capsules) in non-insulin dependent diabetes mellitus.
Journal: Journal of Ayurveda and integrative medicine 20100101
Title: Semecarpus anacardium Linn.: A review.
Journal: Pharmacognosy reviews 20100101
Title: Ocimum sanctum Linn. A reservoir plant for therapeutic applications: An overview.
Journal: Pharmacognosy reviews 20100101
Title: Assessment of the antidiabetic potential of Cassia grandis using an in vivo model.
Journal: Journal of advanced pharmaceutical technology & research 20100101
Title: A comparative study of DNA damage in patients suffering from diabetes and thyroid dysfunction and complications.
Journal: Clinical pharmacology : advances and applications 20100101
Title: Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules.
Journal: Cell metabolism 20091202
Title: Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2.
Journal: Biochimica et biophysica acta 20091201
Title: Beta-cell-mediated signaling predominates over direct alpha-cell signaling in the regulation of glucagon secretion in humans.
Journal: Diabetes care 20091201
Title: Pulsatility of insulin release--a clinically important phenomenon.
Journal: Upsala journal of medical sciences 20091201
Title: Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.
Journal: Cell metabolism 20091104
Title: Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress.
Journal: The Journal of clinical investigation 20091102
Title: Expression of the NH(2)-terminal fragment of RasGAP in pancreatic beta-cells increases their resistance to stresses and protects mice from diabetes.
Journal: Diabetes 20091101
Title: Attenuation of Helicteres isora L. bark extracts on streptozotocin-induced alterations in glycogen and carbohydrate metabolism in albino rats.
Journal: Human & experimental toxicology 20091101
Title: Nonpharmacologic therapy and exercise in the prevention of type 2 diabetes.
Journal: Diabetes care 20091101
Title: Glucose control and cardiovascular disease: is it important? No.
Journal: Diabetes care 20091101
Title: Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity or mortality? No.
Journal: Diabetes care 20091101
Title: Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity/mortality? Yes.
Journal: Diabetes care 20091101
Title: Acute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis.
Journal: The European journal of neuroscience 20091101
Title: Hypoglycemic activity of constituents from Astianthus viminalis in normal and streptozotocin-induced diabetic mice.
Journal: Journal of natural medicines 20091001
Title: Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20091001
Title: Accuracy of Veterans Affairs databases for diagnoses of chronic diseases.
Journal: Preventing chronic disease 20091001
Title: Trace analysis of glyclazide in human plasma at microscale level by mass spectrometry.
Journal: Journal of separation science 20091001
Title: Effect of clonidine on blood glucose levels in euglycemic and alloxan-induced diabetic rats and its interaction with glibenclamide.
Journal: Indian journal of pharmacology 20091001
Title: A1C underestimates glycemia in HIV infection.
Journal: Diabetes care 20090901
Title: Antihyperlipidemic effect of Garlip, a polyherbal formulation in streptozotocin induced diabetic rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901
Title: Transcription factor AP-2beta inhibits glucose-induced insulin secretion in cultured insulin-secreting cell-line.
Journal: Diabetes research and clinical practice 20090901
Title: Involvement of Ca2+/calmodulin kinase II (CaMK II) in genistein-induced potentiation of leucine/glutamine-stimulated insulin secretion.
Journal: Molecules and cells 20090901
Title: Trials review: cardiovascular outcome with intensive glycemic control and implications for patients with type 2 diabetes.
Journal: Postgraduate medicine 20090901
Title: Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance.
Journal: Current drug metabolism 20090901
Title: Malignant Lymphoma with Severe Infiltrative Growth into Skeletal Muscles in WBN/Kob Rats.
Journal: Journal of toxicologic pathology 20090901
Title: Differences between the measured and calculated free serum phenytoin concentrations in epileptic patients.
Journal: Yonsei medical journal 20090831
Title: Epac2: a molecular target for sulfonylurea-induced insulin release.
Journal: Science signaling 20090825
Title: ATP-sensitive potassium currents in rat primary afferent neurons: biophysical, pharmacological properties, and alterations by painful nerve injury.
Journal: Neuroscience 20090818
Title: Enhanced glucose tolerance by SK4 channel inhibition in pancreatic beta-cells.
Journal: Diabetes 20090801
Title: Influence of Helicteres isora administration for diabetes mellitus: Its effect on erythrocyte membrane and antioxidant status.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801
Title: Influence of Helicteres isora administration for diabetes mellitus: the effect on changes in tissue fatty acid composition.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801
Title: Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells.
Journal: Diabetologia 20090801
Title: Plasma membrane depolarization as a determinant of the first phase of insulin secretion.
Journal: American journal of physiology. Endocrinology and metabolism 20090801
Title: Sulphonylurea physicochemical-pharmacokinetic relationships in the pancreas and liver.
Journal: Journal of pharmaceutical sciences 20090801
Title: Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance.
Journal: Diabetes 20090801
Title: The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs.
Journal: Science (New York, N.Y.) 20090731
Title: Antidiabetic activities of Tecoma stans (L.) Juss. ex Kunth.
Journal: Journal of ethnopharmacology 20090715
Title: The effect of growth hormone treatment on metabolic and cardiovascular risk factors is similar in preterm and term short, small for gestational age children.
Journal: Clinical endocrinology 20090701
Title: An in-frame deletion in Kir6.2 (KCNJ11) causing neonatal diabetes reveals a site of interaction between Kir6.2 and SUR1.
Journal: The Journal of clinical endocrinology and metabolism 20090701
Title: A comparative analysis of binding sites between mouse CYP2C38 and CYP2C39 based on homology modeling, molecular dynamics simulation and docking studies.
Journal: Biochimica et biophysica acta 20090701
Title: Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.
Journal: Diabetes 20090701
Title: Relative impact of genotype and enzyme induction on the metabolic capacity of CYP2C9 in healthy volunteers.
Journal: Clinical pharmacology and therapeutics 20090701
Title: Inhibitory effects of leptin on pancreatic alpha-cell function.
Journal: Diabetes 20090701
Title: Hyperglycemic crises in adult patients with diabetes.
Journal: Diabetes care 20090701
Title: Particle characterization of poorly water-soluble drugs using a spray freeze drying technique.
Journal: Chemical & pharmaceutical bulletin 20090701
Title: A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes.
Journal: Journal of clinical biochemistry and nutrition 20090701
Title: Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome.
Journal: PLoS computational biology 20090701
Title: Pancreatic function of spontaneously diabetic torii rats in pre-diabetic stage.
Journal: Experimental animals 20090701
Title: The phenomenon of seasonal pseudohypokalemia: effects of ambient temperature, plasma glucose and role for sodium-potassium-exchanging-ATPase.
Journal: Clinical biochemistry 20090601
Title: G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.
Journal: Diabetes 20090601
Title: Determination of antihyperglycemic drugs in nanomolar concentration levels by micellar electrokinetic chromatography with non-ionic surfactant.
Journal: Journal of chromatography. A 20090515
Title: ATP-sensitive potassium channels control glioma cells proliferation by regulating ERK activity.
Journal: Carcinogenesis 20090501
Title: Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets.
Journal: Diabetes 20090501
Title: Association between increased platelet P-selectin expression and obesity in patients with type 2 diabetes: a BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) substudy.
Journal: Diabetes care 20090501
Title: Equine cytochrome P450 2C92: cDNA cloning, expression and initial characterization.
Journal: Archives of biochemistry and biophysics 20090501
Title: Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels.
Journal: The Journal of biological chemistry 20090403
Title: Activation of the Na+/K+-ATPase by insulin and glucose as a putative negative feedback mechanism in pancreatic beta-cells.
Journal: Pflugers Archiv : European journal of physiology 20090401
Title: Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data.
Journal: Pharmaceutical research 20090401
Title: Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis.
Journal: Diabetes care 20090401
Title: In vitro metabolism and inhibitory effects of pranlukast in human liver microsomes.
Journal: Biological & pharmaceutical bulletin 20090401
Title: A simplified method to determine five cytochrome p450 probe drugs by HPLC in a single run.
Journal: Biological & pharmaceutical bulletin 20090401
Title: Reevaluation of solubility of tolbutamide and polymorphic transformation from Form I to unknown crystal form.
Journal: International journal of pharmaceutics 20090318
Title: The insulinotropic effect of fluoroquinolones.
Journal: Biochemical pharmacology 20090315
Title: Involvement of hippocampal CA3 K(ATP) channels in contextual memory.
Journal: Neuropharmacology 20090301
Title: Insulin resistance without obesity induced by cotton pellet granuloma in mice.
Journal: Laboratory investigation; a journal of technical methods and pathology 20090301
Title: Anti-diabetic drugs in the private and public sector in Dar es Salaam, Tanzania.
Journal: East African medical journal 20090301
Title: A role for ATP-sensitive potassium channels in male sexual behavior.
Journal: Hormones and behavior 20090201
Title: Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function.
Journal: Diabetes 20090201
Title: Glucose and pharmacological modulators of ATP-sensitive K+ channels control [Ca2+]c by different mechanisms in isolated mouse alpha-cells.
Journal: Diabetes 20090201
Title: Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice.
Journal: Diabetes 20090201
Title: Diabetes impairs the vascular recruitment of normal stem cells by oxidant damage, reversed by increases in pAMPK, heme oxygenase-1, and adiponectin.
Journal: Stem cells (Dayton, Ohio) 20090201
Title: Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells.
Journal: Diabetologia 20090201
Title: Topics in type 2 diabetes and insulin resistance.
Journal: Diabetes care 20090201
Title: Interaction of polyphenols with proteins: binding of (-)-epigallocatechin gallate to serum albumin, estimated by induced circular dichroism.
Journal: Chemical & pharmaceutical bulletin 20090201
Title: Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.
Journal: Cell 20090123
Title: Effect of obestatin on insulin, glucagon and somatostatin secretion in the perfused rat pancreas.
Journal: Regulatory peptides 20090108
Title: Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.
Journal: The Journal of clinical investigation 20090105
Title: Calcium influx into MIN6 insulinoma cells induces expression of Egr-1 involving extracellular signal-regulated protein kinase and the transcription factors Elk-1 and CREB.
Journal: European journal of cell biology 20090101
Title: Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.
Journal: Endocrinology 20090101
Title: Kinetics of insulin secretion from MIN6 pseudoislets after encapsulation in a prototype device of a bioartificial pancreas.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090101
Title: Efficacy of peritoneal dialysis of tolbutamide in rats under conditions of the plasma unbound fraction being increased.
Journal: Biopharmaceutics & drug disposition 20090101
Title: Role of MAPK in apolipoprotein CIII-induced apoptosis in INS-1E cells.
Journal: Lipids in health and disease 20090101
Title: The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury.
Journal: PloS one 20090101
Title: FEM-based oxygen consumption and cell viability models for avascular pancreatic islets.
Journal: Theoretical biology & medical modelling 20090101
Title: Modulation of glucose induced oscillatory [Ca2+]i signals by nitric oxide in ob/ob mouse pancreatic beta-cells.
Journal: Mymensingh medical journal : MMJ 20090101
Title: Effects of a low-carbohydrate diet on glycemic control in outpatients with severe type 2 diabetes.
Journal: Nutrition & metabolism 20090101
Title: Human pancreatic islet isolation: Part II: purification and culture of human islets.
Journal: Journal of visualized experiments : JoVE 20090101
Title: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development.
Journal: Current medicinal chemistry 20090101
Title: The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load.
Journal: PloS one 20090101
Title: Rosiglitazone and myocardial infarction in patients previously prescribed metformin.
Journal: PloS one 20090101
Title: A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease.
Journal: Cardiovascular diabetology 20090101
Title: Association of hypoxia inducible factor-1 alpha gene polymorphism with both type 1 and type 2 diabetes in a Caucasian (Hungarian) sample.
Journal: BMC medical genetics 20090101
Title: Interactions between herbal medicines and prescribed drugs: an updated systematic review.
Journal: Drugs 20090101
Title: Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.
Journal: BMC cell biology 20090101
Title: Comparative study of increased plasma quinidine concentration in rats with glycerol- and cisplatin-induced acute renal failure.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: A review of exenatide as adjunctive therapy in patients with type 2 diabetes.
Journal: Drug design, development and therapy 20090101
Title: A practical guide to rodent islet isolation and assessment.
Journal: Biological procedures online 20090101
Title: Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.
Journal: BMJ (Clinical research ed.) 20090101
Title: Evaluation of the activity of P450 enzymes in rats: use of the single marker or combined drug administration.
Journal: Neuro endocrinology letters 20090101
Title: Glinide, but not sulfonylurea, can evoke insulin exocytosis by repetitive stimulation: imaging analysis of insulin exocytosis by secretagogue-induced repetitive stimulations.
Journal: Experimental diabetes research 20090101
Title: Role of potassium channels in stretch-promoted atrial natriuretic factor secretion.
Journal: Journal of the American Society of Hypertension : JASH 20090101
Title: Effect of 2-Hydroxy-4-Methoxy Benzoic Acid from the Roots of Hemidesmus indicus on Streptozotocin-induced Diabetic Rats.
Journal: Indian journal of pharmaceutical sciences 20090101
Title: Drugs impact on CYP-450 enzyme family: A pharmacogenetical study of response variation.
Journal: Indian journal of human genetics 20090101
Title: Update on terbinafine with a focus on dermatophytoses.
Journal: Clinical, cosmetic and investigational dermatology 20090101
Title: Glucose sensing in L cells: a primary cell study.
Journal: Cell metabolism 20081206
Title: Hypoglycemic effect of Mucuna pruriens seed extract on normal and streptozotocin-diabetic rats.
Journal: Fitoterapia 20081201
Title: Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1-selective K(+) channel opener?
Journal: Diabetes 20081201
Title: Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201
Title: Fasting-induced suppression of LH secretion does not require activation of ATP-sensitive potassium channels.
Journal: American journal of physiology. Endocrinology and metabolism 20081201
Title: Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes.
Journal: Acta pharmacologica Sinica 20081201
Title: Alpha-glucosidase inhibitors in the early treatment of type 2 diabetes.
Journal: Vascular health and risk management 20081201
Title: Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets.
Journal: Biophysical journal 20081115
Title: A high-performance liquid chromatography-tandem mass spectrometry method for the clinical combination study of carboplatin and anti-tumor agent eribulin mesylate (E7389) in human plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115
Title: Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5.
Journal: The Journal of biological chemistry 20081114
Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Journal: Journal of medicinal chemistry 20081113
Title: Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia: a nested case-control analysis.
Journal: Diabetes care 20081101
Title: Chronic sustained and intermittent hypoxia reduce function of ATP-sensitive potassium channels in nucleus of the solitary tract.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081101
Title: Analyses of CYP2C in porcine microsomes.
Journal: Basic & clinical pharmacology & toxicology 20081101
Title: Metabolism-independent sugar sensing in central orexin neurons.
Journal: Diabetes 20081001
Title: K(ATP)-channels and glucose-regulated glucagon secretion.
Journal: Trends in endocrinology and metabolism: TEM 20081001
Title: Chronic antidiabetic sulfonylureas in vivo: reversible effects on mouse pancreatic beta-cells.
Journal: PLoS medicine 20081001
Title: Why treatment fails in type 2 diabetes.
Journal: PLoS medicine 20081001
Title: Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.
Journal: Journal of biochemistry 20080901
Title: Pioglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content.
Journal: Diabetes 20080901
Title: Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.
Journal: Diabetes 20080901
Title: Activation of ATP-sensitive potassium channels in rat pancreatic beta-cells by linoleic acid through both intracellular metabolites and membrane receptor signalling pathway.
Journal: The Journal of endocrinology 20080901
Title: Longitudinal changes in insulin sensitivity and body composition of small-for-gestational-age adolescents after cessation of growth hormone treatment.
Journal: The Journal of clinical endocrinology and metabolism 20080901
Title: Bringing light to the dark side of insulin: a journey across the blood-brain barrier.
Journal: Diabetes 20080901
Title: Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.
Journal: Diabetes 20080801
Title: Regulation by glucose of oscillatory electrical activity and 5-HT/insulin release from single mouse pancreatic islets in absence of functional K(ATP) channels.
Journal: Endocrine journal 20080801
Title: Imaging aspects of cardiovascular disease at the cell and molecular level.
Journal: Histochemistry and cell biology 20080801
Title: Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping studies in rats.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080801
Title: Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel.
Journal: PLoS medicine 20080801
Title: [Bax is involved in K ATP-mediated protection of the hippocampal neurons against hypoxic exposure].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801
Title: Proposed new addition to 3Rs for ethical and humane use of rats in pharmacokinetic studies--'Recycle'.
Journal: Drug metabolism letters 20080801
Title: Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.
Journal: Endocrinology 20080701
Title: Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. III. In vitro-in vivo correlation with fluconazole.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701
Title: Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. II. In vitro-in vivo correlation with ketoconazole.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701
Title: Glucose metabolism in vivo in four commonly used inbred mouse strains.
Journal: Diabetes 20080701
Title: Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice.
Journal: Diabetes 20080701
Title: Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea.
Journal: Pharmacogenetics and genomics 20080701
Title: Cytochrome P450 2C9 mediated metabolism in people with and without cancer.
Journal: International journal of clinical pharmacology and therapeutics 20080701
Title: INGAP-PP up-regulates the expression of genes and proteins related to K+ ATP channels and ameliorates Ca2+ handling in cultured adult rat islets.
Journal: Regulatory peptides 20080605
Title: Human hair follicles contain two forms of ATP-sensitive potassium channels, only one of which is sensitive to minoxidil.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080601
Title: Hydrogen peroxide-induced translocation of glycolipid-anchored (c)AMP-hydrolases to lipid droplets mediates inhibition of lipolysis in rat adipocytes.
Journal: British journal of pharmacology 20080601
Title: Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinical.
Journal: The AAPS journal 20080601
Title: Pharmaceutical particle engineering via spray drying.
Journal: Pharmaceutical research 20080501
Title: Low intense physical exercise in normobaric hypoxia leads to more weight loss in obese people than low intense physical exercise in normobaric sham hypoxia.
Journal: Sleep & breathing = Schlaf & Atmung 20080501
Title: Ovarian steroids stimulate adenosine triphosphate-sensitive potassium (KATP) channel subunit gene expression and confer responsiveness of the gonadotropin-releasing hormone pulse generator to KATP channel modulation.
Journal: Endocrinology 20080501
Title: A Kir6.2 mutation causing severe functional effects in vitro produces neonatal diabetes without the expected neurological complications.
Journal: Diabetologia 20080501
Title: Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone.
Journal: The Journal of steroid biochemistry and molecular biology 20080501
Title: A novel ABCC8 (SUR1)-dependent mechanism of metabolism-excitation uncoupling.
Journal: The Journal of biological chemistry 20080404
Title: Resting energy expenditure in insulin resistance falls with decompensation of insulin secretion in obese children.
Journal: Journal of pediatric endocrinology & metabolism : JPEM 20080401
Title: Prevention of chemotherapy-induced nausea and vomiting: focus on fosaprepitant.
Journal: Therapeutics and clinical risk management 20080401
Title: Chronic hypoglycemic effect of Malmea depressa root on n5-streptozotocin diabetic rats.
Journal: Journal of ethnopharmacology 20080305
Title: Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.
Journal: The Journal of endocrinology 20080301
Title: [Neonatal diabetes mellitus].
Journal: Arquivos brasileiros de endocrinologia e metabologia 20080301
Title: Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel.
Journal: The Journal of biological chemistry 20080227
Title: Influence of chalcone analogues on serum glucose levels in hyperglycemic rats.
Journal: Chemico-biological interactions 20080215
Title: Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide.
Journal: Journal of ethnopharmacology 20080212
Title: Cytochrome P450 2C9 *2 and *3 polymorphisms and the dose and effect of sulfonylurea in type II diabetes mellitus.
Journal: Clinical pharmacology and therapeutics 20080201
Title: The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080201
Title: Impaired glucose-stimulated insulin secretion is coupled with exocrine pancreatic lesions in the Cohen diabetic rat.
Journal: Diabetes 20080201
Title: Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.
Journal: European journal of clinical pharmacology 20080201
Title: Inhibitory effects of fruit juices on cytochrome P450 2C9 activity in vitro.
Journal: Bioscience, biotechnology, and biochemistry 20080201
Title: Effect of acute hyperglycaemia and/or hyperinsulinaemia on proinflammatory gene expression, cytokine production and neutrophil function in humans.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20080201
Title: Glucose induces synchronous mitochondrial calcium oscillations in intact pancreatic islets.
Journal: Cell calcium 20080101
Title: Inhibition of striatal dopamine release by CB1 receptor activation requires nonsynaptic communication involving GABA, H2O2, and KATP channels.
Journal: Neurochemistry international 20080101
Title: Protection of pancreatic beta-cells: is it feasible?
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20080101
Title: Attenuation of Biochemical Parameters in Streptozotocin-induced Diabetic Rats by Oral Administration of Extracts and Fractions of Cephalotaxus sinensis.
Journal: Journal of clinical biochemistry and nutrition 20080101
Title: PAX4 enhances beta-cell differentiation of human embryonic stem cells.
Journal: PloS one 20080101
Title: Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis.
Journal: BMC medical genetics 20080101
Title: Functional role of Ile264 in CYP2C8: mutations affect haem incorporation and catalytic activity.
Journal: Drug metabolism and pharmacokinetics 20080101
Title: Clinical drugs that interact with St. John's wort and implication in drug development.
Journal: Current pharmaceutical design 20080101
Title: Utility of a single adjusting compartment: a novel methodology for whole body physiologically-based pharmacokinetic modelling.
Journal: Theoretical biology & medical modelling 20080101
Title: Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome.
Journal: PloS one 20080101
Title: TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatitis but may interact with SPINK1 and CTSB mutations in predicting diabetes.
Journal: BMC medical genetics 20080101
Title: Drug-therapy networks and the prediction of novel drug targets.
Journal: Journal of biology 20080101
Title: Acne vulgaris, mental health and omega-3 fatty acids: a report of cases.
Journal: Lipids in health and disease 20080101
Title: Role of cytochrome P450 in drug interactions.
Journal: Nutrition & metabolism 20080101
Title: Few alterations in clinical pathology and histopathology observed in a CYP2C18&19 humanized mice model.
Journal: Acta veterinaria Scandinavica 20080101
Title: Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
Title: Limited applicability of 7-methoxy-4-trifluoromethylcoumarin as a CYP2C9-selective substrate.
Journal: Pharmacological reports : PR 20080101
Title: Hypoglycemic activity of Hemidesmus indicus R. Br. on streptozotocin-induced diabetic rats.
Journal: International journal of diabetes in developing countries 20080101
Title: Recent challenges in insulin delivery systems: a review.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: Formulation and characterization of mucoadhesive buccal films of glipizide.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: Hypoglycemic and hypolipidemic activity of ethanolic extract of Salvadora oleoides in normal and alloxan-induced diabetic rats.
Journal: Indian journal of pharmacology 20080101
Title: Nutrient control of insulin secretion in perifused adult pig islets.
Journal: Diabetes & metabolism 20071201
Title: Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.
Journal: Diabetes 20071201
Title: Effect of methamphetamine on cytochrome P450 activity.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20071201
Title: Short- and long-term mortality after acute myocardial infarction: comparison of patients with and without diabetes mellitus.
Journal: European journal of epidemiology 20071201
Title: Antidiabetic properties of 2,5-dihydroxy-4,3'-di(beta-D-glucopyranosyloxy)-trans-stilbene from mulberry (Morus bombycis koidzumi) root in streptozotocin-induced diabetic rats.
Journal: Journal of medicinal food 20071201
Title: Summary of the 2007 European Society of Hypertension (ESH) and European Society of Cardiology (ESC) guidelines for the management of arterial hypertension.
Journal: Vascular health and risk management 20071201
Title: A review of nateglinide in the management of patients with type 2 diabetes.
Journal: Vascular health and risk management 20071201
Title: [A case-control study of risk factors for myelodysplastic syndromes].
Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20071201
Title: Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071127
Title: Synthesis and antidiabetic activity of 2,5-disubstituted-3-imidazol-2-yl-pyrrolo[2,3-b]pyridines and thieno[2,3-b]pyridines.
Journal: Bioorganic & medicinal chemistry 20071101
Title: Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071101
Title: Assessment of antidiabetic potential of Cynodon dactylon extract in streptozotocin diabetic rats.
Journal: Journal of ethnopharmacology 20071101
Title: Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced diabetic rats.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20071101
Title: Attenuation of insulin secretion by insulin-like growth factor binding protein-1 in pancreatic beta-cells.
Journal: Biochemical and biophysical research communications 20071012
Title: High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease.
Journal: Diabetologia 20071001
Title: Response normalized liquid chromatography nanospray ionization mass spectrometry.
Journal: Journal of the American Society for Mass Spectrometry 20071001
Title: Characterization of cytochrome P450-mediated drug metabolism in cats.
Journal: Journal of veterinary pharmacology and therapeutics 20071001
Title: A review of pioglitazone HCL and glimepiride in the treatment of type 2 diabetes.
Journal: Vascular health and risk management 20071001
Title: Gonadotropin-releasing hormone neurons express K(ATP) channels that are regulated by estrogen and responsive to glucose and metabolic inhibition.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070919
Title: The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells.
Journal: FEBS letters 20070904
Title: Sulfonylurea and glinide reduce insulin content, functional expression of K(ATP) channels, and accelerate apoptotic beta-cell death in the chronic phase.
Journal: Diabetes research and clinical practice 20070901
Title: Congenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescue.
Journal: Diabetes 20070901
Title: Synthesis of 3,8,9-trisubstituted-1,7,9-triaza-fluorene-6-carboxylic acid derivatives as a new class of insulin secretagogues.
Journal: Bioorganic & medicinal chemistry 20070901
Title: Memantine inhibits ATP-dependent K+ conductances in dopamine neurons of the rat substantia nigra pars compacta.
Journal: The Journal of pharmacology and experimental therapeutics 20070801
Title: Iptakalim, a vascular ATP-sensitive potassium (KATP) channel opener, closes rat pancreatic beta-cell KATP channels and increases insulin release.
Journal: The Journal of pharmacology and experimental therapeutics 20070801
Title: The role of mitochondria in protection of the heart by preconditioning.
Journal: Biochimica et biophysica acta 20070801
Title: [Protection mechanisms of ATP-sensitive K channels on hippocampal CA1 neurons during chronic severe hypoxia].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070801
Title: Dioscorea as the principal herb of Die-Huang-Wan, a widely used herbal mixture in China, for improvement of insulin resistance in fructose-rich chow-fed rats.
Journal: Journal of ethnopharmacology 20070725
Title: Transgenic expression of a dominant negative K(ATP) channel subunit in the mouse endothelium: effects on coronary flow and endothelin-1 secretion.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701
Title: Nateglinide and mitiglinide, but not sulfonylureas, induce insulin secretion through a mechanism mediated by calcium release from endoplasmic reticulum.
Journal: The Journal of pharmacology and experimental therapeutics 20070701
Title: In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies.
Journal: Journal of mass spectrometry : JMS 20070701
Title: Validated method for rapid inhibition screening of six cytochrome P450 enzymes by liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601
Title: Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.
Journal: Diabetes 20070601
Title: A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.
Journal: PLoS biology 20070601
Title: Identification and partial characterization of a novel CYP2C9 splicing variant encoding a protein lacking eight amino acid residues.
Journal: Drug metabolism and pharmacokinetics 20070601
Title: [Simultaneous determination of the inhibitory potency of compounds on the activity of five cytochrome P-450 enzymes using a cocktail probe substrates method].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070601
Title: Reversibility of enantiotropically related polymorphic transformations from a practical viewpoint: thermal analysis of kinetically reversible/irreversible polymorphic transformations.
Journal: Journal of pharmaceutical sciences 20070501
Title: Prolonged exposure to homocysteine results in diminished but reversible pancreatic beta-cell responsiveness to insulinotropic agents.
Journal: Diabetes/metabolism research and reviews 20070501
Title: Design, synthesis, and biological evaluation of substituted-N-(thieno[2,3-b]pyridin-3-yl)-guanidines, N-(1H-pyrrolo[2,3-b]pyridin-3-yl)-guanidines, and N-(1H-indol-3-yl)-guanidines.
Journal: Bioorganic & medicinal chemistry 20070501
Title: Ginsenoside Rh2 is one of the active principles of Panax ginseng root to improve insulin sensitivity in fructose-rich chow-fed rats.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070501
Title: Indian herbs and herbal drugs used for the treatment of diabetes.
Journal: Journal of clinical biochemistry and nutrition 20070501
Title: The Anti-Obesity Effect of the Palatinose-Based Formula Inslow is Likely due to an Increase in the Hepatic PPAR-alpha and Adipocyte PPAR-gamma Gene Expressions.
Journal: Journal of clinical biochemistry and nutrition 20070501
Title: Rapid inhibition of neurons in the dorsal motor nucleus of the vagus by leptin.
Journal: Endocrinology 20070401
Title: PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
Journal: PLoS genetics 20070401
Title: Involvement of chloride channel coupled GABA(C) receptors in the peripheral antinociceptive effect induced by GABA(C) receptor agonist cis-4-aminocrotonic acid.
Journal: Life sciences 20070313
Title: Does the preferred orientation of crystallites in tablets affect the intrinsic dissolution?
Journal: Journal of pharmaceutical and biomedical analysis 20070312
Title: Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: Characterization of the physiological spaces and distribution of tolbutamide in the perfused rat pancreas.
Journal: Pharmaceutical research 20070301
Title: Monoglycerides and fatty acids from Ibervillea sonorae root: isolation and hypoglycemic activity.
Journal: Planta medica 20070301
Title: Pharmacological and molecular characterization of ATP-sensitive K(+) conductances in CART and NPY/AgRP expressing neurons of the hypothalamic arcuate nucleus.
Journal: Neuroscience 20070209
Title: Adult pancreatic islets require differential pax6 gene dosage.
Journal: Biochemical and biophysical research communications 20070202
Title: Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070201
Title: Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070201
Title: Glucose inhibits glucagon secretion by a direct effect on mouse pancreatic alpha cells.
Journal: Diabetologia 20070201
Title: Electrophysiological and pharmacological characterization of the K(ATP) channel involved in the K+-current responses to FSH and adenosine in the follicular cells of Xenopus oocyte.
Journal: The journal of physiological sciences : JPS 20070201
Title: Structures of steroidal alkaloid oligoglycosides, robeneosides A and B, and antidiabetogenic constituents from the Brazilian medicinal plant Solanum lycocarpum.
Journal: Journal of natural products 20070201
Title: An ATP-binding mutation (G334D) in KCNJ11 is associated with a sulfonylurea-insensitive form of developmental delay, epilepsy, and neonatal diabetes.
Journal: Diabetes 20070201
Title: Sulfonylurea compounds uncouple the glucose dependence of the insulinotropic effect of glucagon-like peptide 1.
Journal: Diabetes 20070201
Title: The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance.
Journal: Diabetes care 20070201
Title: Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in humans and their simultaneous use in the 'cocktail' approach.
Journal: Clinical pharmacology and therapeutics 20070201
Title: Impact of clinical characteristics of individual metabolic syndrome on the severity of insulin resistance in Chinese adults.
Journal: Journal of Korean medical science 20070201
Title: 3T3-L1 adipocytes induce dysfunction of MIN6 insulin-secreting cells via multiple pathways mediated by secretory factors in a co-culture system.
Journal: Endocrine 20070201
Title: Effect of crude extract and fractions from Vitex megapotamica leaves on hyperglycemia in alloxan-diabetic rats.
Journal: Journal of ethnopharmacology 20070103
Title: In vivo antidiabetic and antioxidant potential of Helichrysum plicatum ssp. plicatum capitulums in streptozotocin-induced-diabetic rats.
Journal: Journal of ethnopharmacology 20070103
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: A novel model for the prediction of drug-drug interactions in humans based on in vitro cytochrome p450 phenotypic data.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070101
Title: Antagonism of the insulinotropic action of first generation imidazolines by openers of K(ATP) channels.
Journal: Biochemical pharmacology 20070101
Title: The effects induced by the sulphonylurea glibenclamide on the neonatal rat spinal cord indicate a novel mechanism to control neuronal excitability and inhibitory neurotransmission.
Journal: British journal of pharmacology 20070101
Title: CYP2C76-mediated species difference in drug metabolism: a comparison of pitavastatin metabolism between monkeys and humans.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070101
Title: Homocysteine-induced impairment of insulin secretion from clonal pancreatic BRIN-BD11 beta-cells is not prevented by catalase.
Journal: Pancreas 20070101
Title: Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta-cells.
Journal: The Journal of endocrinology 20070101
Title: Effect of creatine on the pancreatic beta-cell.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070101
Title: The KATP channel is critical for calcium sequestration into non-ER compartments in mouse pancreatic beta cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Title: The blockade of K(+)-ATP channels has neuroprotective effects in an in vitro model of brain ischemia.
Journal: International review of neurobiology 20070101
Title: A discrete Single Delay Model for the Intra-Venous Glucose Tolerance Test.
Journal: Theoretical biology & medical modelling 20070101
Title: Induction of insulin secretion in engineered liver cells by nitric oxide.
Journal: BMC physiology 20070101
Title: Loss of sugar detection by GLUT2 affects glucose homeostasis in mice.
Journal: PloS one 20070101
Title: Pitfalls in diagnosing a small cystic insulinoma: a case report.
Journal: Journal of medical case reports 20070101
Title: An insulin-like modular basis for the evolution of glucose transporters (GLUT) with implications for diabetes.
Journal: Evolutionary bioinformatics online 20070101
Title: Cloning of a cDNA encoding a novel marmoset CYP2C enzyme, expression in yeast cells and characterization of its enzymatic functions.
Journal: Biochemical pharmacology 20061215
Title: A1 adenosine receptor-mediated modulation of neuronal ATP-sensitive K channels in rat substantia nigra.
Journal: Brain research 20061208
Title: CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20061201
Title: Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes.
Journal: Pflugers Archiv : European journal of physiology 20061201
Title: Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061201
Title: Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing.
Journal: Diabetes 20061201
Title: Nutrient control of insulin secretion in isolated normal human islets.
Journal: Diabetes 20061201
Title: Chick pancreatic B islets as an alternative in vitro model for screening insulin secretagogues.
Journal: Poultry science 20061201
Title: Stimulus-secretion coupling of hypotonicity-induced insulin release in BRIN-BD11 cells.
Journal: Endocrine 20061201
Title: In-vivo assessment of antidiabetic and antioxidant activities of grapevine leaves (Vitis vinifera) in diabetic rats.
Journal: Journal of ethnopharmacology 20061124
Title: Enzyme source effects on CYP2C9 kinetics and inhibition.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20061101
Title: Improvement of insulin resistance by miracle fruit (Synsepalum dulcificum) in fructose-rich chow-fed rats.
Journal: Phytotherapy research : PTR 20061101
Title: Baclofen, an agonist at peripheral GABAB receptors, induces antinociception via activation of TEA-sensitive potassium channels.
Journal: British journal of pharmacology 20061101
Title: Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers.
Journal: Journal of clinical pharmacology 20061101
Title: Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.
Journal: Biochemical Society transactions 20061101
Title: Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism.
Journal: The FEBS journal 20061101
Title: Antidiabetic, antioxidant and antihyperlipidemic status of Heliotropium zeylanicum extract on streptozotocin-induced diabetes in rats.
Journal: Biological & pharmaceutical bulletin 20061101
Title: OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
Journal: PLoS medicine 20061101
Title: Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects.
Journal: Pharmacology & therapeutics 20061001
Title: Iptakalim modulates ATP-sensitive K(+) channels in dopamine neurons from rat substantia nigra pars compacta.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: [The inhibition of CYP2C9 isoenzyme in Cunninghamella blakesleeana AS 3. 910].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20061001
Title: Modelling the electrical activity of pancreatic alpha-cells based on experimental data from intact mouse islets.
Journal: Journal of biological physics 20061001
Title: Biotransformation of tolbutamide to 4'-hydroxytolbutamide by the fungus Cunninghamella blakesleeana.
Journal: Applied microbiology and biotechnology 20060901
Title: Intestinal and hepatic metabolic activity of five cytochrome P450 enzymes: impact on prediction of first-pass metabolism.
Journal: The Journal of pharmacology and experimental therapeutics 20060901
Title: Acute insulin response (AIR): review of protocols and clinical interest in islet transplantation.
Journal: Diabetes & metabolism 20060901
Title: Molecular modelling of K(ATP) channel blockers-ADP/ ATP carrier interactions.
Journal: Systems biology 20060901
Title: Actions of glucagon-like peptide-1 on KATP channel-dependent and -independent effects of glucose, sulphonylureas and nateglinide.
Journal: The Journal of endocrinology 20060901
Title: Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.
Journal: The New England journal of medicine 20060803
Title: Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations.
Journal: The New England journal of medicine 20060803
Title: CYP2C76, a novel cytochrome P450 in cynomolgus monkey, is a major CYP2C in liver, metabolizing tolbutamide and testosterone.
Journal: Molecular pharmacology 20060801
Title: Antiallodynic effect of etidronate, a bisphosphonate, in rats with adjuvant-induced arthritis: involvement of ATP-sensitive K+ channels.
Journal: Neuropharmacology 20060801
Title: Polysaccharide peptides from COV-1 strain of Coriolus versicolor inhibit tolbutamide 4-hydroxylation in the rat in vitro and in vivo.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060801
Title: Tolbutamide reduces glioma cell proliferation by increasing connexin43, which promotes the up-regulation of p21 and p27 and subsequent changes in retinoblastoma phosphorylation.
Journal: Glia 20060801
Title: K+-ATP-channel-related protein complexes: potential transducers in the regulation of epithelial tight junction permeability.
Journal: Journal of cell science 20060801
Title: In vivo evidence for nitric oxide-mediated calcium-activated potassium-channel activation during human endotoxemia.
Journal: Circulation 20060801
Title: Development of dosage design of hepatic metabolizing drugs using serum albumin level in chronic hepatic failure.
Journal: Biological & pharmaceutical bulletin 20060801
Title: First phase of glucose-stimulated insulin secretion from MIN 6 cells does not always require extracellular calcium influx.
Journal: Journal of pharmacological sciences 20060801
Title: Cell specificity of the cytoplasmic Ca2+ response to tolbutamide is impaired in beta-cells from hyperglycemic mice.
Journal: The Journal of endocrinology 20060801
Title: Micronization and polymorphic conversion of tolbutamide and barbital by rapid expansion of supercritical solutions.
Journal: Drug development and industrial pharmacy 20060801
Title: Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K channel pathway.
Journal: The European journal of neuroscience 20060801
Title: Peritoneal dialysis alters tolbutamide pharmacokinetics in rats with experimental acute renal failure.
Journal: Drug metabolism and pharmacokinetics 20060801
Title: Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
Journal: The Journal of clinical investigation 20060703
Title: The clinical applications of a systems approach.
Journal: PLoS medicine 20060701
Title: Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis.
Journal: Diabetologia 20060701
Title: Prediction of metabolic drug clearance in humans: in vitro-in vivo extrapolation vs allometric scaling.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060701
Title: Inhibitory effects of cytostatically active 6-aminobenzo[c]phenanthridines on cytochrome P450 enzymes in human hepatic microsomes.
Journal: Basic & clinical pharmacology & toxicology 20060701
Title: Host-guest chemistry of tolbutamide.
Journal: Molecules (Basel, Switzerland) 20060623
Title: Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: implications for ingestive behaviour.
Journal: The Journal of physiology 20060601
Title: Prediction of in vivo drug clearance from in vitro data. II: potential inter-ethnic differences.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060601
Title: Role of site-specific binding to plasma albumin in drug availability to brain.
Journal: The Journal of pharmacology and experimental therapeutics 20060501
Title: Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression.
Journal: Neuroscience letters 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter.
Journal: Diabetes 20060501
Title: Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.
Journal: The Journal of endocrinology 20060501
Title: Regulators for blood glucose level affect gene expression of aquaporin 3.
Journal: Biological & pharmaceutical bulletin 20060501
Title: In silico pharmacogenetics of warfarin metabolism.
Journal: Nature biotechnology 20060501
Title: Cynomolgus monkey cytochrome P450 2C43: cDNA cloning, heterologous expression, purification and characterization.
Journal: Journal of biochemistry 20060501
Title: MIN6 beta-cell-beta-cell interactions influence insulin secretory responses to nutrients and non-nutrients.
Journal: Biochemical and biophysical research communications 20060428
Title: The Zn2+-transporting pathways in pancreatic beta-cells: a role for the L-type voltage-gated Ca2+ channel.
Journal: The Journal of biological chemistry 20060407
Title: Antihyperglycemic effect of the fruit-pulp of Eugenia jambolana in experimental diabetes mellitus.
Journal: Journal of ethnopharmacology 20060406
Title: Depth profiling of compression-induced disorders and polymorphic transition on tablet surfaces with grazing incidence X-ray diffraction.
Journal: Pharmaceutical research 20060401
Title: Induction of cytochrome P450-dependent monooxygenase by extracts of the medicinal herb Salvia miltiorrhiza.
Journal: The Journal of pharmacy and pharmacology 20060401
Title: Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells.
Journal: The Journal of endocrinology 20060401
Title: Effect of Helicteres isora bark extract on blood glucose and hepatic enzymes in experimental diabetes.
Journal: Die Pharmazie 20060401
Title: Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets.
Journal: American journal of physiology. Endocrinology and metabolism 20060301
Title: Glibenclamide-induced apoptosis is specifically enhanced by expression of the sulfonylurea receptor isoform SUR1 but not by expression of SUR2B or the mutant SUR1(M1289T).
Journal: The Journal of pharmacology and experimental therapeutics 20060301
Title: Evaluation of microdosing to assess pharmacokinetic linearity in rats using liquid chromatography-tandem mass spectrometry.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060301
Title: Possible activation of the NO-cyclic GMP-protein kinase G-K+ channels pathway by gabapentin on the formalin test.
Journal: Pharmacology, biochemistry, and behavior 20060301
Title: Supercritical fluid chromatography/tandem mass spectrometric method for analysis of pharmaceutical compounds in metabolic stability samples.
Journal: Journal of pharmaceutical and biomedical analysis 20060224
Title: Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids.
Journal: Endocrinology 20060201
Title: Neuronal responses to transient hypoglycaemia in the dorsal vagal complex of the rat brainstem.
Journal: The Journal of physiology 20060201
Title: 5-HT uptake blockade prevents the increasing effect of K(ATP) channel blockers on electrically evoked [3H]-5-HT release in rat and mouse neocortical slices.
Journal: Neurochemistry international 20060201
Title: Increased levels of cyclins D1 and D3 after inhibition of gap junctional communication in astrocytes.
Journal: Journal of neurochemistry 20060201
Title: Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing.
Journal: Diabetes 20060201
Title: Effect of oral administration of clinically relevant doses of dexamethasone on regulation of cytochrome P450 subfamilies in hepatic microsomes from dogs and rats.
Journal: American journal of veterinary research 20060201
Title: Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells.
Journal: PLoS biology 20060201
Title: Inhibition of human cytochrome P450 isoforms and NADPH-CYP reductase in vitro by 15 herbal medicines, including Epimedii herba.
Journal: Journal of clinical pharmacy and therapeutics 20060201
Title: Clinical features and insulin regulation in infants with a syndrome of prolonged neonatal hyperinsulinism.
Journal: The Journal of pediatrics 20060201
Title: Development and validation of HTS flux assay for endogenously expressed chloride channels in a CHO-K1 cell line.
Journal: Assay and drug development technologies 20060201
Title: Drug nanoparticle formation from drug/HPMC/SDS ternary ground mixtures.
Journal: Die Pharmazie 20060201
Title: KATP channels in mouse spermatogenic cells and sperm, and their role in capacitation.
Journal: Developmental biology 20060115
Title: Diversity of Cl(-) channels.
Journal: Cellular and molecular life sciences : CMLS 20060101
Title: Hypoglycemic effects of the wood of Taxus yunnanensis on streptozotocin-induced diabetic rats and its active components.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20060101
Title: Serum aminotransferase activity as a predictor for estimation of total clearance of hepatically metabolized drugs in rats with acute hepatic failure.
Journal: Biological & pharmaceutical bulletin 20060101
Title: Influences of drugs on the oxygen uptake rate and biosorption of activated sludge.
Journal: Biological & pharmaceutical bulletin 20060101
Title: Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion.
Journal: Cell metabolism 20060101
Title: Antidiabetic and hypolipidaemic effects of a methanol/methylene-chloride extract of Laportea ovalifolia (Urticaceae), measured in rats with alloxan-induced diabetes.
Journal: Annals of tropical medicine and parasitology 20060101
Title: Ginkgo biloba: evaluation of CYP2C9 drug interactions in vitro and in vivo.
Journal: American journal of therapeutics 20060101
Title: Effects of sulfonylureas on mitochondrial ATP-sensitive K+ channels in cardiac myocytes: implications for sulfonylurea controversy.
Journal: Diabetes/metabolism research and reviews 20060101
Title: Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor.
Journal: Annals of clinical microbiology and antimicrobials 20060101
Title: Ultra-low flow nanospray for the normalization of conventional liquid chromatography/mass spectrometry through equimolar response: standard-free quantitative estimation of metabolite levels in drug discovery.
Journal: Rapid communications in mass spectrometry : RCM 20060101
Title: Prediction models for insulin resistance in girls with premature adrenarche. The premature adrenarche insulin resistance score: PAIR score.
Journal: Hormone research 20060101
Title: Dimensional analysis of MINMOD leads to definition of the disposition index of glucose regulation and improved simulation algorithm.
Journal: Biomedical engineering online 20060101
Title: Analysis of coding variants in the betacellulin gene in type 2 diabetes and insulin secretion in African American subjects.
Journal: BMC medical genetics 20060101
Title: Glucose induces anion conductance and cytosol-to-membrane transposition of ICln in INS-1E rat insulinoma cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101
Title: Effects of irsogladine on P450-isoform specific activities in human hepatic microsomes.
Journal: Arzneimittel-Forschung 20060101
Title: Inhibition of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by sulfonylurea glibenclamide.
Journal: European journal of pharmacology 20051219
Title: Effect of St John's wort (Hypericum perforatum) on cytochrome P-450 activity in perfused rat liver.
Journal: Life sciences 20051205
Title: Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.
Journal: The Journal of pharmacology and experimental therapeutics 20051201
Title: Effects of I(Ks) channel inhibitors in insulin-secreting INS-1 cells.
Journal: Pflugers Archiv : European journal of physiology 20051201
Title: Effect of propiverine on cytochrome P450 enzymes: a cocktail interaction study in healthy volunteers.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20051201
Title: Probable activation of the opioid receptor-nitric oxide-cyclic GMP-K+ channels pathway by codeine.
Journal: Pharmacology, biochemistry, and behavior 20051201
Title: The novel formulation design of O/W microemulsion for improving the gastrointestinal absorption of poorly water soluble compounds.
Journal: International journal of pharmaceutics 20051123
Title: Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101
Title: Increasing the decrement in insulin secretion improves glucagon responses to hypoglycemia in advanced type 2 diabetes.
Journal: Diabetes care 20051101
Title: Oxygen and glucose deprivation induces major dysfunction in the somatosensory cortex of the newborn rat.
Journal: The European journal of neuroscience 20051101
Title: Hypoglycemic activity of a new carbohydrate isolated from the roots of Psacalium peltatum.
Journal: Chemical & pharmaceutical bulletin 20051101
Title: Testosterone rapidly stimulates insulin release from isolated pancreatic islets through a non-genomic dependent mechanism.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051101
Title: Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026
Title: Acute effects of 6-hydroxydopamine on dopaminergic neurons of the rat substantia nigra pars compacta in vitro.
Journal: Neurotoxicology 20051001
Title: Protective role of hydrogen peroxide in oxygen-deprived dopaminergic neurones of the rat substantia nigra.
Journal: The Journal of physiology 20051001
Title: Changes in muscle mRNAs for hexokinase, phosphofructokinase-1 and glycogen synthase in acute and persistent hypoglycemia induced by tolbutamide in chickens.
Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20051001
Title: Sulphonylurea sensitivity and enriched expression implicate inward rectifier K+ channels in Drosophila melanogaster renal function.
Journal: The Journal of experimental biology 20051001
Title: Increase of insulin sensitivity by stevioside in fructose-rich chow-fed rats.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001
Title: Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets.
Journal: FEBS letters 20050926
Title: Tungstate stimulates insulin release and inhibits somatostatin output in the perfused rat pancreas.
Journal: European journal of pharmacology 20050905
Title: Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line.
Journal: The Journal of biological chemistry 20050902
Title: The use of sandwich-cultured rat hepatocytes to determine the intrinsic clearance of compounds with different extraction ratios: 7-ethoxycoumarin and warfarin.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050901
Title: Identification and quantification of 8 sulfonylureas with clinical toxicology interest by liquid chromatography-ion-trap tandem mass spectrometry and library searching.
Journal: Clinical chemistry 20050901
Title: ATP and sulfonylurea sensitivity of mutant ATP-sensitive K+ channels in neonatal diabetes: implications for pharmacogenomic therapy.
Journal: Diabetes 20050901
Title: Effect of antifungal drugs on cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 activities in human liver microsomes.
Journal: Biological & pharmaceutical bulletin 20050901
Title: Catalytic activities of human cytochrome P450 2C9*1, 2C9*3 and 2C9*13.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050901
Title: Heme impairs allosterically drug binding to human serum albumin Sudlow's site I.
Journal: Biochemical and biophysical research communications 20050826
Title: Nateglinide, a non-sulfonylurea rapid insulin secretagogue, increases pancreatic islet blood flow in rats.
Journal: European journal of pharmacology 20050822
Title: Sulfhydryl oxidation reduces hippocampal susceptibility to hypoxia-induced spreading depression by activating BK channels.
Journal: Journal of neurophysiology 20050801
Title: Characterization of microsomal cytochrome P450-dependent monooxygenases in the rat olfactory mucosa.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801
Title: Pharmacological evidence for the activation of Ca2+-activated K+ channels by meloxicam in the formalin test.
Journal: Pharmacology, biochemistry, and behavior 20050801
Title: Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans.
Journal: Environmental health perspectives 20050801
Title: Improvement of insulin resistance by Acanthopanax senticosus root in fructose-rich chow-fed rats.
Journal: Clinical and experimental pharmacology & physiology 20050801
Title: The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type O/W microemulsion I: enhancing effects on oral bioavailability of poorly water soluble compounds in rats and beagle dogs.
Journal: Drug metabolism and pharmacokinetics 20050801
Title: [Influence of cytochrom P450 CYP2C9 polymorphism on the pharmacokinetics of tolbutamide metabolism using oligonucleotide genotyping microarray].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050801
Title: Cytosolic Cl- ions in the regulation of secretory and endocytotic activity in melanotrophs from mouse pituitary tissue slices.
Journal: The Journal of physiology 20050715
Title: Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701
Title: Glibenclamide stimulates fluid secretion in rodent cholangiocytes through a cystic fibrosis transmembrane conductance regulator-independent mechanism.
Journal: Gastroenterology 20050701
Title: Twenty-four hour tolbutamide plasma concentration as a phenotypic measure of CYP2C9 activity.
Journal: European journal of clinical pharmacology 20050601
Title: Relationship of P450 2C9 genetic polymorphisms in Chinese and the pharmacokinetics of tolbutamide.
Journal: Journal of clinical pharmacy and therapeutics 20050601
Title: Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release.
Journal: Diabetes 20050601
Title: Electrochemical characterisation of the human cytochrome P450 CYP2C9.
Journal: Biochemical pharmacology 20050515
Title: Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans.
Journal: Pancreas 20050501
Title: Analysis of the mechanism underlying the peripheral antinociceptive action of sildenafil in the formalin test.
Journal: European journal of pharmacology 20050411
Title: Evaluation of the hypoglycemic effect and antioxidant activity of three Viscum album subspecies (European mistletoe) in streptozotocin-diabetic rats.
Journal: Journal of ethnopharmacology 20050408
Title: Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Journal: Journal of medicinal chemistry 20050407
Title: Delta-opioid receptor agonist SNC80 induces peripheral antinociception via activation of ATP-sensitive K+ channels.
Journal: European journal of pharmacology 20050404
Title: Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401
Title: A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.
Journal: Diabetologia 20050401
Title: HIV-1 transactivator of transcription protein induces mitochondrial hyperpolarization and synaptic stress leading to apoptosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050401
Title: Similarities of K+ATP channel expression and Ca2+ changes in pancreatic beta cells and hypothalamic neurons.
Journal: Pancreas 20050401
Title: Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1alpha mutation carriers.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20050401
Title: Hypoglycemic and antihyperglycemic effect of Gmelina asiatica LINN. in normal and in alloxan induced diabetic rats.
Journal: Biological & pharmaceutical bulletin 20050401
Title: [Effects of Chinese herbal medicines on intestinal drug absorption].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050401
Title: Effect of Sanguis draxonis (a Chinese traditional herb) on the formation of insulin resistance in rats.
Journal: Diabetes research and clinical practice 20050401
Title: Novel and established potassium channel openers stimulate hair growth in vitro: implications for their modes of action in hair follicles.
Journal: The Journal of investigative dermatology 20050401
Title: No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extract.
Journal: Planta medica 20050401
Title: The increase in gap junctional communication decreases the rate of glucose uptake in C6 glioma cells by releasing hexokinase from mitochondria.
Journal: Brain research 20050328
Title: Acute and chronic hypoglycemic effect of Ibervillea sonorae root extracts-II.
Journal: Journal of ethnopharmacology 20050321
Title: Oxymorphone extended release does not affect CYP2C9 or CYP3A4 metabolic pathways.
Journal: Journal of clinical pharmacology 20050301
Title: Improvement of insulin resistance by panax ginseng in fructose-rich chow-fed rats.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050301
Title: Hypoglycemic effects of Murraya koenigii on normal and alloxan-diabetic rabbits.
Journal: Journal of ethnopharmacology 20050227
Title: Metabotropic glutamate receptor activity induces a novel oscillatory pattern in neonatal rat hypoglossal motoneurones.
Journal: The Journal of physiology 20050215
Title: Lansoprazole enantiomer activates human liver microsomal CYP2C9 catalytic activity in a stereospecific and substrate-specific manner.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050201
Title: Genotype-phenotype correlations in children with congenital hyperinsulinism due to recessive mutations of the adenosine triphosphate-sensitive potassium channel genes.
Journal: The Journal of clinical endocrinology and metabolism 20050201
Title: Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas.
Journal: Biochemical pharmacology 20050201
Title: The pore-forming subunit of the K(ATP) channel is an important molecular target for LPS-induced vascular hyporeactivity in vitro.
Journal: British journal of pharmacology 20050201
Title: Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.
Journal: British journal of pharmacology 20050201
Title: Mechanism of the hypoglycemic effect of stevioside, a glycoside of Stevia rebaudiana.
Journal: Planta medica 20050201
Title: Crystal forms of tolbutamide from acetonitrile and 1-octanol: effect of solvent, humidity and compression pressure.
Journal: International journal of pharmaceutics 20050120
Title: Sulfonylurea induced beta-cell apoptosis in cultured human islets.
Journal: The Journal of clinical endocrinology and metabolism 20050101
Title: Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide.
Journal: Biochemical pharmacology 20050101
Title: Prediction of in vitro intrinsic clearance from hepatocytes: comparison of suspensions and monolayer cultures.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101
Title: Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus.
Journal: Diabetes 20050101
Title: Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).
Journal: Diabetes 20050101
Title: Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101
Title: Clinical consequences of cytochrome P450 2C9 polymorphisms.
Journal: Clinical pharmacology and therapeutics 20050101
Title: Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature.
Journal: BMC physiology 20050101
Title: Participation of ATP-sensitive K+ channels in the peripheral antinociceptive effect of fentanyl in rats.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050101
Title: Prolactin, an activator of epithelial Na+ channel, inhibits basolateral K+ channels in adult tree frog skin.
Journal: Zoological science 20050101
Title: Simultaneous determination of paracetamol and dextropropoxyphene in human plasma by liquid chromatography/tandem mass spectrometry: application to clinical bioequivalence studies.
Journal: Rapid communications in mass spectrometry : RCM 20050101
Title: The 'Statinth' wonder of the world: a panacea for all illnesses or a bubble about to burst.
Journal: Journal of negative results in biomedicine 20050101
Title: Cardiovascular risk factors associated with insulin resistance: effects of oral antidiabetic agents.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101
Title: Antihyperlipidemic and antiperoxidative effect of Diasulin, a polyherbal formulation in alloxan induced hyperglycemic rats.
Journal: BMC complementary and alternative medicine 20050101
Title: High-throughput screening of inhibitory potential of nine cytochrome P450 enzymes in vitro using liquid chromatography/tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20050101
Title: Hypoglycemic and antiperglycemic effects of Semecarpus anacardium linn in normal and alloxan-induced diabetic rats.
Journal: Journal of herbal pharmacotherapy 20050101
Title: Assay for high glucose-mediated islet cell sensitization to apoptosis induced by streptozotocin and cytokines.
Journal: Biological procedures online 20050101
Title: Bench-to-bedside review: Antidotal treatment of sulfonylurea-induced hypoglycaemia with octreotide.
Journal: Critical care (London, England) 20050101
Title: Effects of etodolac on P450 isoform-specific activities in human hepatic microsomes.
Journal: Arzneimittel-Forschung 20050101
Title: Exubera(®) (inhaled insulin): an evidence-based review of its effectiveness in the management of diabetes.
Journal: Core evidence 20050101
Title: ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.
Journal: Diabetes 20041201
Title: Massive augmentation of stimulated insulin secretion induced by fatty acid-free BSA in rat pancreatic islets.
Journal: Diabetes 20041201
Title: Insulin resistance and impaired insulin secretion in prenatally androgenized male rhesus monkeys.
Journal: The Journal of clinical endocrinology and metabolism 20041201
Title: Hypoglycemic and antihyperglycemic effect of Semecarpus anacardium Linn in normal and streptozotocin-induced diabetic rats.
Journal: Methods and findings in experimental and clinical pharmacology 20041201
Title: Comparison of equivalence and determination of diagnostic utility of min-mod and clamp methods for insulin resistance in diabetes free subjects: a meta-analysis.
Journal: Endocrine 20041201
Title: A pancreatic islet-specific microRNA regulates insulin secretion.
Journal: Nature 20041111
Title: Detection of anti-diabetics in equine plasma and urine by liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041105
Title: A new ATP-sensitive K+ channel-independent mechanism is involved in glucose-excited neurons of mouse arcuate nucleus.
Journal: Diabetes 20041101
Title: Tolbutamide potentiates the volume-regulated anion channel current in rat pancreatic beta cells.
Journal: Diabetologia 20041101
Title: Insulin secretion, peripheral insulin sensitivity and insulin-receptor binding in subjects with different degrees of obesity.
Journal: Diabetes & metabolism 20041101
Title: Insulin secretory characteristics of monkey pancreatic islets: a simple method of islet isolation and the effect of various density gradients on separation.
Journal: Diabetes research and clinical practice 20041001
Title: Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy.
Journal: Diabetes 20041001
Title: The comparative interaction of human and bovine serum albumins with CYP2C9 in human liver microsomes.
Journal: Life sciences 20040917
Title: CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products.
Journal: The Journal of pharmacology and experimental therapeutics 20040901
Title: Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes.
Journal: Biochemical pharmacology 20040901
Title: Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus.
Journal: Journal of neurochemistry 20040901
Title: A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study.
Journal: British journal of clinical pharmacology 20040901
Title: Improved dissolution of an insoluble drug using a 4-fluid nozzle spray-drying technique.
Journal: Chemical & pharmaceutical bulletin 20040901
Title: Familial leucine-sensitive hypoglycemia of infancy due to a dominant mutation of the beta-cell sulfonylurea receptor.
Journal: The Journal of clinical endocrinology and metabolism 20040901
Title: Pulses of external ATP aid to the synchronization of pancreatic beta-cells by generating premature Ca(2+) oscillations.
Journal: Biochemical pharmacology 20040815
Title: Modeling the in vitro intrinsic clearance of the slowly metabolized compound tolbutamide determined in sandwich-cultured rat hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040801
Title: The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides.
Journal: Diabetes 20040801
Title: Does the aspartic acid to asparagine substitution at position 76 in the pancreas duodenum homeobox gene (PDX1) cause late-onset type 2 diabetes?
Journal: Diabetes care 20040801
Title: Discovery of new potentially defective alleles of human CYP2C9.
Journal: Pharmacogenetics 20040801
Title: Establishment and application of in vitro membrane potential assays in cell lines with endogenous or recombinant expression of ATP-sensitive potassium channels (Kir6.2/SUR1) using a fluorescent probe kit.
Journal: Journal of biomolecular screening 20040801
Title: Enzyme activity analysis of CYP2C18 with exon 5 skipped.
Journal: Acta pharmacologica Sinica 20040801
Title: Identification of the main human cytochrome P450 enzymes involved in safrole 1'-hydroxylation.
Journal: Chemical research in toxicology 20040801
Title: Testosterone modulates K(+)ATP channels in Sertoli cell membrane via the PLC-PIP2 pathway.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040801
Title: Tolbutamide uptake via pH- and membrane-potential-dependent transport mechanism in mouse brain capillary endothelial cell line.
Journal: Drug metabolism and pharmacokinetics 20040801
Title: Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.
Journal: The Journal of biological chemistry 20040730
Title: Ginkgo biloba extract modifies hypoglycemic action of tolbutamide via hepatic cytochrome P450 mediated mechanism in aged rats.
Journal: Life sciences 20040716
Title: Chronic exposure to tolbutamide and glibenclamide impairs insulin secretion but not transcription of K(ATP) channel components.
Journal: Pharmacological research 20040701
Title: An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701
Title: Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
Journal: Diabetes 20040701
Title: Identification of a novel variant CYP2C9 allele in Chinese.
Journal: Pharmacogenetics 20040701
Title: Study of the involvement of K+ channels in the peripheral antinociception of the kappa-opioid receptor agonist bremazocine.
Journal: European journal of pharmacology 20040628
Title: New hypoglycaemic agents selected by molecular topology.
Journal: International journal of pharmaceutics 20040618
Title: Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells.
Journal: The Journal of physiology 20040615
Title: In vitro induction of adult hepatic progenitor cells into insulin-producing cells.
Journal: Biochemical and biophysical research communications 20040604
Title: Validated assays for human cytochrome P450 activities.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040601
Title: Direct interference of HIV protease inhibitors with pancreatic beta-cell function.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040601
Title: Reversal of streptozotocin-induced hyperglycemia by transplantation of pseudoislets consisting of beta cells derived from ductal cells.
Journal: Endocrine journal 20040601
Title: Pharmacokinetic interactions of drugs with St John's wort.
Journal: Journal of psychopharmacology (Oxford, England) 20040601
Title: Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures.
Journal: Human & experimental toxicology 20040601
Title: Cytochrome P450 2C9 phenotyping using low-dose tolbutamide.
Journal: European journal of clinical pharmacology 20040501
Title: Beta-cell toxicity of ATP-sensitive K+ channel-blocking insulin secretagogues.
Journal: Biochemical pharmacology 20040501
Title: Endothelin-1 stimulates the translocation and upregulation of both glucose transporter and hexokinase in astrocytes: relationship with gap junctional communication.
Journal: Journal of neurochemistry 20040501
Title: Comparison of fresh and cryopreserved rat hepatocyte suspensions for the prediction of in vitro intrinsic clearance.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040501
Title: Interaction of dexloxiglumide, a cholecystokinin type-1 receptor antagonist, with human cytochromes P450.
Journal: Biopharmaceutics & drug disposition 20040501
Title: Contrasting diabetes phenotypes associated with hepatocyte nuclear factor-1alpha and -1beta mutations.
Journal: Diabetes care 20040501
Title: Acute and long-term effects of nateglinide on insulin secretory pathways.
Journal: British journal of pharmacology 20040501
Title: Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside from Bauhinia forficata leaves.
Journal: Journal of natural products 20040501
Title: Potential of pranlukast and zafirlukast in the inhibition of human liver cytochrome P450 enzymes.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501
Title: Alteration of beta-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes.
Journal: Molecular and cellular endocrinology 20040430
Title: Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.
Journal: The New England journal of medicine 20040429
Title: [3T3-L1 adipocytes reduces Kir6.2 channel expression in MIN6 insulin-secreting cells in vitro].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20040425
Title: Fluorescence microscopy studies with a fluorescent glibenclamide derivative, a high-affinity blocker of pancreatic beta-cell ATP-sensitive K+ currents.
Journal: Biochemical pharmacology 20040415
Title: Inhibition of glucose-induced electrical activity in rat pancreatic beta-cells by DCPIB, a selective inhibitor of volume-sensitive anion currents.
Journal: European journal of pharmacology 20040405
Title: Diclofenac-induced peripheral antinociception is associated with ATP-sensitive K+ channels activation.
Journal: Life sciences 20040402
Title: A store-operated mechanism determines the activity of the electrically excitable glucagon-secreting pancreatic alpha-cell.
Journal: Cell calcium 20040401
Title: Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040401
Title: Simultaneous determination of glipizide and rosiglitazone unbound drug concentrations in plasma by equilibrium dialysis and liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040305
Title: Evaluation of potential inductive effects of aprepitant on cytochrome P450 3A4 and 2C9 activity.
Journal: Journal of clinical pharmacology 20040301
Title: Phase I and II enzyme characterization of two sources of HepG2 cell lines.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040301
Title: Systematic screening of potential beta-cell imaging agents.
Journal: Biochemical and biophysical research communications 20040220
Title: Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells.
Journal: European journal of pharmacology 20040220
Title: Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.
Journal: Endocrinology 20040201
Title: Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20040201
Title: Pharmacokinetic and pharmacodynamic assessment of a five-probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1.
Journal: British journal of clinical pharmacology 20040201
Title: Nutrients induce different Ca(2+) signals in cytosol and nucleus in pancreatic beta-cells.
Journal: Diabetes 20040201
Title: The hormonal phenotype of Nonclassic 3 beta-hydroxysteroid dehydrogenase (HSD3B) deficiency in hyperandrogenic females is associated with insulin-resistant polycystic ovary syndrome and is not a variant of inherited HSD3B2 deficiency.
Journal: The Journal of clinical endocrinology and metabolism 20040201
Title: Acute insulin responses to calcium and tolbutamide do not differentiate focal from diffuse congenital hyperinsulinism.
Journal: The Journal of clinical endocrinology and metabolism 20040201
Title: Beneficial effects of addition of oral spray insulin (Oralin) on insulin secretion and metabolic control in subjects with type 2 diabetes mellitus suboptimally controlled on oral hypoglycemic agents.
Journal: Diabetes technology & therapeutics 20040201
Title: Inhibitory effects of the monoamine oxidase inhibitor tranylcypromine on the cytochrome P450 enzymes CYP2C19, CYP2C9, and CYP2D6.
Journal: Cellular and molecular neurobiology 20040201
Title: Transepithelial permeation of tolbutamide across the human intestinal cell line, Caco-2.
Journal: Drug metabolism and pharmacokinetics 20040201
Title: Serum aminotransferase activity as a predictor of clearance of drugs metabolized by CYP isoforms in rats with acute hepatic failure induced by carbon tetrachloride.
Journal: International journal of pharmaceutics 20040128
Title: Involvement of K+ channels and calcium-dependent pathways in the action of T3 on amino acid accumulation and membrane potential in Sertoli cells of immature rat testis.
Journal: Life sciences 20040123
Title: Modulation of the excitability of cholinergic basal forebrain neurones by KATP channels.
Journal: The Journal of physiology 20040115
Title: Is impairment of ischaemic preconditioning by sulfonylurea drugs clinically important?
Journal: Heart (British Cardiac Society) 20040101
Title: Regulation by sulfanylurea receptor type 1 of a non-selective cation channel involved in cytotoxic edema of reactive astrocytes.
Journal: Journal of neurosurgical anesthesiology 20040101
Title: Is acarbose equivalent to tolbutamide as first treatment for newly diagnosed type 2 diabetes in general practice? A randomised controlled trial.
Journal: Diabetes research and clinical practice 20040101
Title: Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose.
Journal: Diabetes 20040101
Title: Early ionic and membrane potential changes caused by the pesticide rotenone in striatal cholinergic interneurons.
Journal: Experimental neurology 20040101
Title: Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation.
Journal: The Journal of clinical endocrinology and metabolism 20040101
Title: The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo.
Journal: Clinical pharmacology and therapeutics 20040101
Title: Dupuytren's disease in Bosnia and Herzegovina. An epidemiological study.
Journal: BMC musculoskeletal disorders 20040101
Title: The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes.
Journal: American journal of therapeutics 20040101
Title: A buffer temperature controlled perifusion system to study temperature dependence and kinetics of insulin secretion in MIN6 pseudoislets.
Journal: Journal of pharmacological and toxicological methods 20040101
Title: Chinese herbal medicines for type 2 diabetes mellitus.
Journal: The Cochrane database of systematic reviews 20040101
Title: The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+ channels in the rat insulinoma cell line, CRI-G1.
Journal: BMC pharmacology 20040101
Title: HLA DR phenotypic frequencies and genetic risk of Type 1 diabetes in west region of Algeria, Tlemcen.
Journal: BMC genetics 20040101
Title: Oral spray insulin in treatment of type 2 diabetes: a comparison of efficacy of the oral spray insulin (Oralin) with subcutaneous (SC) insulin injection, a proof of concept study.
Journal: Diabetes/metabolism research and reviews 20040101
Title: The UGDP controversy: thirty-four years of contentious ambiguity laid to rest.
Journal: Perspectives in biology and medicine 20040101
Title: Rapid determination of five probe drugs and their metabolites in human plasma and urine by liquid chromatography/tandem mass spectrometry: application to cytochrome P450 phenotyping studies.
Journal: Rapid communications in mass spectrometry : RCM 20040101
Title: Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation.
Journal: BMC neuroscience 20040101
Title: Constitutive nitric oxide synthases in rat pancreatic islets: direct imaging of glucose-induced nitric oxide production in beta-cells.
Journal: Pflugers Archiv : European journal of physiology 20031201
Title: 'Open access' generic method for continuous determination of major human CYP450 probe substrates/metabolites and its application in drug metabolism studies.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20031201
Title: Restoration of first-phase insulin secretion by the imidazoline compound LY374284 in pancreatic islets of diabetic db/db mice.
Journal: Annals of the New York Academy of Sciences 20031201
Title: Clinical relevance of genetic polymorphisms in the human CYP2C9 gene.
Journal: European journal of clinical investigation 20031101
Title: Pharmacokinetics of tolbutamide after oral administration to rabbits with folate-induced renal failure.
Journal: Archives of pharmacal research 20031101
Title: Comparison of the Gordon-Taylor and Couchman-Karasz equations for prediction of the glass transition temperature of glass solutions of drug and polyvinylpyrrolidone prepared by melt extrusion.
Journal: Die Pharmazie 20031101
Title: Genetic cause of hyperglycaemia and response to treatment in diabetes.
Journal: Lancet (London, England) 20031018
Title: Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism.
Journal: Diabetes 20031001
Title: Analysis of synthetic anti-diabetic drugs in adulterated traditional Chinese medicines by high-performance capillary electrophoresis.
Journal: Journal of pharmaceutical and biomedical analysis 20030919
Title: Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030917
Title: Clinical and molecular characterization of a dominant form of congenital hyperinsulinism caused by a mutation in the high-affinity sulfonylurea receptor.
Journal: Diabetes 20030901
Title: ATP-sensitive potassium channels induced in liver cells after transfection with insulin cDNA and the GLUT 2 transporter regulate glucose-stimulated insulin secretion.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901
Title: New aspects of neurotransmitter release and exocytosis: involvement of Ca2+/calmodulin-dependent phosphorylation of synapsin I in insulin exocytosis.
Journal: Journal of pharmacological sciences 20030901
Title: Evaluation of HOMA and QUICKI as measures of insulin sensitivity in prepubertal children.
Journal: Pediatric diabetes 20030901
Title: A novel approach to in situ characterization of pancreatic beta-cells.
Journal: Pflugers Archiv : European journal of physiology 20030801
Title: Inhaled insulin for the treatment of diabetes: projects and devices.
Journal: Expert opinion on pharmacotherapy 20030801
Title: The NO-cGMP-K+ channel pathway participates in the antinociceptive effect of diclofenac, but not of indomethacin.
Journal: Pharmacology, biochemistry, and behavior 20030801
Title: Hepatic delta9, delta6, and delta5 desaturations in non-insulin-dependent diabetes mellitus eSS rats.
Journal: Lipids 20030801
Title: No major difference in inhibitory susceptibility between CYP2C9.1 and CYP2C9.3.
Journal: European journal of clinical pharmacology 20030701
Title: Dimethyl disulfide exerts insecticidal neurotoxicity through mitochondrial dysfunction and activation of insect K(ATP) channels.
Journal: Journal of neurophysiology 20030701
Title: Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9.
Journal: Clinical pharmacology and therapeutics 20030701
Title: Effect of endothelin-1 on astrocytic protein content.
Journal: Glia 20030601
Title: Functional involvement of sulphonylurea receptor (SUR) type 1 and 2B in the activity of pig urethral ATP-sensitive K+ channels.
Journal: British journal of pharmacology 20030601
Title: Nesidioblastosis in adults: a challenging cause of organic hyperinsulinism.
Journal: European journal of clinical investigation 20030601
Title: Diterpene quinone tanshinone IIA selectively inhibits mouse and human cytochrome p4501A2.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030601
Title: Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression.
Journal: The Biochemical journal 20030501
Title: Loperamide mobilizes intracellular Ca2+ stores in insulin-secreting HIT-T15 cells.
Journal: British journal of pharmacology 20030501
Title: Na+ channel inactivation: a comparative study between pancreatic islet beta-cells and adrenal chromaffin cells in rat.
Journal: The Journal of physiology 20030401
Title: Retention of transporter activities in cryopreserved, isolated rat hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20030401
Title: Glutamate-dependent inhibition of dopamine release in striatum is mediated by a new diffusible messenger, H2O2.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401
Title: L-carnitine consecutively administered to patients on hemodialysis improves beta-cell response.
Journal: The International journal of artificial organs 20030401
Title: Rapid induction of insulin resistance in opioid mu-receptor knock-out mice.
Journal: Neuroscience letters 20030320
Title: Role of conserved Asp293 of cytochrome P450 2C9 in substrate recognition and catalytic activity.
Journal: The Biochemical journal 20030315
Title: Implications of pharmacogenetics for individualizing drug treatment and for study design.
Journal: Journal of molecular medicine (Berlin, Germany) 20030301
Title: Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides.
Journal: The Journal of physiology 20030215
Title: A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology.
Journal: British journal of clinical pharmacology 20030201
Title: Differential effects of K(ATP) channel blockers on [(3)H]-noradrenaline overflow after short- and long-term exposure to (+)-oxaprotiline or desipramine.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030201
Title: Antihyperglycemic and hypoglycemic effect of Aporosa lindleyana in normal and alloxan induced diabetic rats.
Journal: Journal of ethnopharmacology 20030201
Title: Leptin fully suppresses acetylcholine-induced insulin secretion and is reversed by tolbutamide in isolated perfused chicken pancreas.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030201
Title: Calcium-dependent translocation of cytosolic phospholipase A2 in pancreatic beta-cells.
Journal: Biochemical and biophysical research communications 20030124
Title: Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.
Journal: Archives of biochemistry and biophysics 20030101
Title: High-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20030101
Title: Possible involvement of potassium channels in peripheral antinociception induced by metamizol: lack of participation of ATP-sensitive K+ channels.
Journal: Pharmacology, biochemistry, and behavior 20030101
Title: Tolbutamide, flurbiprofen, and losartan as probes of CYP2C9 activity in humans.
Journal: Journal of clinical pharmacology 20030101
Title: Differential selectivity of insulin secretagogues: mechanisms, clinical implications, and drug interactions.
Journal: Journal of diabetes and its complications 20030101
Title: Maternal-fetal transport of hypoglycaemic drugs.
Journal: Clinical pharmacokinetics 20030101
Title: Barriers to self-monitoring of blood glucose among adults with diabetes in an HMO: a cross sectional study.
Journal: BMC health services research 20030101
Title: Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells.
Journal: Journal of pharmacological sciences 20030101
Title: The juice of fresh leaves of Catharanthus roseus Linn. reduces blood glucose in normal and alloxan diabetic rabbits.
Journal: BMC complementary and alternative medicine 20030101
Title: [A 50-year history of new drugs in Japan-the development and progress of anti-diabetic drugs and the epidemiological aspects of diabetes mellitus].
Journal: Yakushigaku zasshi 20030101
Title: Study of the anti-hyperglycemic effect of anti-diabetic plants in rabbits with impaired glucose tolerance.
Journal: Proceedings of the Western Pharmacology Society 20030101
Title: Effect of ficus relegiosa on blood glucose and total lipid levels of normal and alloxan diabetic rabbits.
Journal: Journal of Ayub Medical College, Abbottabad : JAMC 20030101
Title: The relationship between oxidative metabolism and lipid peroxidation in rat liver microsomes.
Journal: Research communications in molecular pathology and pharmacology 20030101
Title: Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201
Title: Glucose-dependent regulation of rhythmic action potential firing in pancreatic beta-cells by K(ATP)-channel modulation.
Journal: The Journal of physiology 20021201
Title: Increase of insulin sensitivity in diabetic rats received die-huang-wan, a herbal mixture used in Chinese traditional medicine.
Journal: Acta pharmacologica Sinica 20021201
Title: Sulfonylurea stimulation of insulin secretion.
Journal: Diabetes 20021201
Title: Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas.
Journal: Diabetes 20021201
Title: Increased metabolizing activities of the tricarboxylic acid cycle and decreased drug metabolism in hepatocellular carcinoma.
Journal: Carcinogenesis 20021201
Title: How does glucose evoke electrical activity in the pancreatic beta-cell?
Journal: Diabetes & metabolism 20021201
Title: The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking.
Journal: European journal of biochemistry 20021101
Title: BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.
Journal: The Journal of clinical endocrinology and metabolism 20021101
Title: Evaluation of cytochrome P4502C9 metabolic activity with tolbutamide in CYP2C91 heterozygotes.
Journal: Clinical pharmacology and therapeutics 20021101
Title: Establishment of a transgenic cell line stably expressing human cytochrome P450 2C18 and identification of a CYP2C18 clone with exon 5 missing.
Journal: World journal of gastroenterology 20021015
Title: Dynamics of glucose-induced membrane recruitment of protein kinase C beta II in living pancreatic islet beta-cells.
Journal: The Journal of biological chemistry 20021004
Title: The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta.
Journal: Cardiovascular research 20021001
Title: Cell-type specific depression of neuronal excitability in rat hippocampus by activation of ATP-sensitive potassium channels.
Journal: European biophysics journal : EBJ 20021001
Title: Acute insulin response tests for the differential diagnosis of congenital hyperinsulinism.
Journal: The Journal of clinical endocrinology and metabolism 20021001
Title: The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels.
Journal: Neuropharmacology 20021001
Title: Likelihood methods for measuring statistical evidence.
Journal: Statistics in medicine 20020915
Title: The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related.
Journal: The Journal of biological chemistry 20020906
Title: Glucose-sensing in glucagon-like peptide-1-secreting cells.
Journal: Diabetes 20020901
Title: Differential interactions of nateglinide and repaglinide on the human beta-cell sulphonylurea receptor 1.
Journal: Diabetes 20020901
Title: Calmodulin overexpression causes Ca(2+)-dependent apoptosis of pancreatic beta cells, which can be prevented by inhibition of nitric oxide synthase.
Journal: Laboratory investigation; a journal of technical methods and pathology 20020901
Title: Validated HPLC method for the determination of celecoxib in human serum and its application in a clinical pharmacokinetic study.
Journal: Die Pharmazie 20020901
Title: A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor.
Journal: Analytical biochemistry 20020815
Title: Amino acid residues affecting the activities of human cytochrome P450 2C9 and 2C19.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020801
Title: [Acute insulin response to tolbutamide of pancreatic beta-cell].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020801
Title: Effect of albumin and cytosol on enzyme kinetics of tolbutamide hydroxylation and on inhibition of CYP2C9 by gemfibrozil in human liver microsomes.
Journal: The Journal of pharmacology and experimental therapeutics 20020701
Title: Sulfonylurea receptor gene 16-3 polymorphism - association with sulfonylurea or insulin treatment in type 2 diabetic subjects.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20020701
Title: [Development of simplified and rapid detection assay for genetic polymorphisms influencing drug response and its clinical applications].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020701
Title: Neural control of the heart: developmental changes in ionic conductances in mammalian intrinsic cardiac neurons.
Journal: Autonomic neuroscience : basic & clinical 20020628
Title: Screening, library-assisted identification and validated quantification of oral antidiabetics of the sulfonylurea-type in plasma by atmospheric pressure chemical ionization liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020615
Title: Effect of albumin on phenytoin and tolbutamide metabolism in human liver microsomes: an impact more than protein binding.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020601
Title: Hypoglycemic and hypotriglyceridemic effects of tolbutamide in triphenyltin chloride-induced diabetic rabbits.
Journal: Veterinary and human toxicology 20020601
Title: In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes.
Journal: American journal of veterinary research 20020601
Title: Desensitization of insulin secretion.
Journal: Biochemical pharmacology 20020601
Title: Effects of Kampo extracts on drug metabolism in rat liver microsomes: Rhei Rhizoma extract and Glycyrrhizae Radix extract inhibit drug oxidation.
Journal: Japanese journal of pharmacology 20020601
Title: Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by dipyrone.
Journal: European journal of pharmacology 20020524
Title: Functional expression of Kir 6.1/SUR1-K(ATP) channels in frog retinal Müller glial cells.
Journal: Glia 20020501
Title: Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells.
Journal: The Journal of physiology 20020501
Title: Transient neonatal diabetes mellitus, type 4, type 1 diabetes mellitus, or MODY: which disease is it, anyway?
Journal: Journal of pediatric endocrinology & metabolism : JPEM 20020501
Title: Co-ordinated Ca(2+)-signalling within pancreatic islets: does beta-cell entrainment require a secreted messenger.
Journal: Cell calcium 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Cloning of cytochrome P-450 2C9 cDNA from human liver and its expression in CHL cells.
Journal: World journal of gastroenterology 20020415
Title: [High sensitivity to sulphonylurea treatment in 2 patients with maturity-onset diabetes of the young type 3].
Journal: Nederlands tijdschrift voor geneeskunde 20020413
Title: Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels.
Journal: Neurochemistry international 20020401
Title: Leptin inhibits rat hippocampal neurons via activation of large conductance calcium-activated K+ channels.
Journal: Nature neuroscience 20020401
Title: Intraislet hyperinsulinemia prevents the glucagon response to hypoglycemia despite an intact autonomic response.
Journal: Diabetes 20020401
Title: Pulsatile insulin release from islets isolated from three subjects with type 2 diabetes.
Journal: Diabetes 20020401
Title: Dopamine selectively reduces GABA(B) transmission onto dopaminergic neurones by an unconventional presynaptic action.
Journal: The Journal of physiology 20020401
Title: History of diabetes mellitus.
Journal: Saudi medical journal 20020401
Title: Enzyme and plasma protein induction by multiple oral administrations of phenobarbital at a therapeutic dosage regimen in dogs.
Journal: Journal of veterinary pharmacology and therapeutics 20020401
Title: Phototoxicity to diuretics and antidiabetics in the cultured keratinocyte cell line HaCaT: evaluation by clonogenic assay and single cell gel electrophoresis Comet assay).
Journal: Photodermatology, photoimmunology & photomedicine 20020401
Title: Leptin affects the electrical activity of neurones in the hypothalamic supraoptic nucleus.
Journal: Brain research bulletin 20020315
Title: Utility of rat liver slices to estimate hepatic clearance for application in physiologically based pharmacokinetic modeling: a study with tolbutamide, a compound with low extraction efficiency.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020301
Title: The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020301
Title: CYP2C9 polymorphism: impact on tolbutamide pharmacokinetics and response.
Journal: Pharmacogenetics 20020301
Title: Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers.
Journal: Pharmacogenetics 20020301
Title: Effects of CYP2C19 and CYP2C9 genetic polymorphisms on the disposition of and blood glucose lowering response to tolbutamide in humans.
Journal: Pharmacogenetics 20020301
Title: Characterisation of the effects of potassium channel modulating agents on mouse intestinal smooth muscle.
Journal: The Journal of pharmacy and pharmacology 20020301
Title: Pharmacological evidence for the activation of K(+) channels by diclofenac.
Journal: European journal of pharmacology 20020301
Title: Membrane potential dependent modulations of calcium oscillations in insulin-secreting INS-1 cells.
Journal: Cell calcium 20020301
Title: The effect of bergamottin on diazepam plasma levels and P450 enzymes in beagle dogs.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020201
Title: S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B.
Journal: The Biochemical journal 20020201
Title: Triterpenes from Agarista mexicana as potential antidiabetic agents.
Journal: Phytotherapy research : PTR 20020201
Title: Novel properties of peptides derived from the sequence coded by exon 26A of human elastin.
Journal: The international journal of biochemistry & cell biology 20020201
Title: Overexpression of the Na/Ca exchanger shapes stimulus-induced cytosolic Ca(2+) oscillations in insulin-producing BRIN-BD11 cells.
Journal: Diabetes 20020201
Title: Feedback control of the ATP-sensitive K(+) current by cytosolic Ca(2+) contributes to oscillations of the membrane potential in pancreatic beta-cells.
Journal: Diabetes 20020201
Title: Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
Journal: Pharmaceutical research 20020201
Title: Evidence that glucose-induced electrical activity in rat pancreatic beta-cells does not require KATP channel inhibition.
Journal: The Journal of membrane biology 20020201
Title: Mercuric chloride alters the membrane potential and intracellular calcium level in mouse pancreatic islet cells.
Journal: Journal of toxicology and environmental health. Part A 20020201
Title: Inhibitory effects of H1-antihistamines on CYP2D6- and CYP2C9-mediated drug metabolic reactions in human liver microsomes.
Journal: European journal of clinical pharmacology 20020201
Title: Inhibition of glucose-induced electrical activity by 4-hydroxytamoxifen in rat pancreatic beta-cells.
Journal: Cellular signalling 20020101
Title: A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion.
Journal: Diabetes 20020101
Title: Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion.
Journal: Diabetes care 20020101
Title: ATP-independent anoxic activation of ATP-sensitive K+ channels in dorsal vagal neurons of juvenile mice in situ.
Journal: Neuroscience 20020101
Title: Tolbutamide alters glucose transport and metabolism in the embryonic mouse heart.
Journal: Teratology 20020101
Title: New trends in the development of oral antidiabetic drugs.
Journal: Current medicinal chemistry 20020101
Title: Chemical anoxia activates ATP-sensitive and blocks Ca(2+)-dependent K(+) channels in rat dorsal vagal neurons in situ.
Journal: Neuroscience 20020101
Title: The evolving role of oral insulin in the treatment of diabetes using a novel RapidMist System.
Journal: Diabetes/metabolism research and reviews 20020101
Title: Few cultured rat primary sensory neurons express a tolbutamide-sensitive K+ current.
Journal: Journal of cellular and molecular medicine 20020101
Title: Application of cDNA microarray technology to in vitro toxicology and the selection of genes for a real-time RT-PCR-based screen for oxidative stress in Hep-G2 cells.
Journal: Toxicologic pathology 20020101
Title: Fondaparinux sodium is not metabolised in mammalian liver fractions and does not inhibit cytochrome P450-mediated metabolism of concomitant drugs.
Journal: Clinical pharmacokinetics 20020101
Title: Trends in oral antihyperglycemic and insulin use in the Nova Scotia senior population (1993-1999).
Journal: The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20020101
Title: Role of the nitric oxide-cyclic GMP-K+ channel pathway in the antinociception induced by atrial natriuretic peptide (ANP) and diclofenac.
Journal: Proceedings of the Western Pharmacology Society 20020101
Title: Metabolic fate of pitavastatin (NK-104), a new inhibitor of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase. Effects on drug-metabolizing systems in rats and humans.
Journal: Arzneimittel-Forschung 20020101
Title: Effect of garlic on cardiovascular disorders: a review.
Journal: Nutrition journal 20020101
Title: Pharmacokinetics of tolbutamide after oral administration in rabbits with folate-induced renal failure.
Journal: Research communications in molecular pathology and pharmacology 20020101
Title: Molecular cloning of monkey CYP2C43 cDNA and expression in yeast.
Journal: Drug metabolism and pharmacokinetics 20020101
Title: Effects of serum albumin and liver cytosol on CYP2C9- and CYP3A4-mediated drug metabolism.
Journal: Drug metabolism and pharmacokinetics 20020101
Title: Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. I. Secretory and morphological studies.
Journal: Biochemical pharmacology 20011215
Title: Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. II. Electrophysiological and fluorimetric studies.
Journal: Biochemical pharmacology 20011215
Title: Proliferation of C6 glioma cells is blunted by the increase in gap junction communication caused by tolbutamide.
Journal: FEBS letters 20011207
Title: Opioid receptor modulation of a metabolically sensitive ion channel in rat amygdala neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201
Title: Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats.
Journal: Diabetes 20011201
Title: Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin.
Journal: Pharmacogenetics 20011201
Title: The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro.
Journal: European journal of clinical pharmacology 20011201
Title: The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive K+ channels and insulin secretion: comparison with the sulfonylureas and nateglinide.
Journal: European journal of pharmacology 20011109
Title: Monoclonal antibodies specific and inhibitory to human cytochromes P450 2C8, 2C9, and 2C19.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20011101
Title: Application of the PKCYP-test to predict the amount of in vivo CYP2C11 using tolbutamide as a probe.
Journal: Biological & pharmaceutical bulletin 20011101
Title: In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
Journal: British journal of clinical pharmacology 20011101
Title: An aqueous extract of the green leafy vegetable Ipomoea aquatica is as effective as the oral hypoglycaemic drug tolbutamide in reducing the blood sugar levels of Wistar rats.
Journal: Phytotherapy research : PTR 20011101
Title: Effects of tolbutamide and N-benzoyl-D-phenylalanine (NBDP) on the regulation of [Ca2+]i oscillations in mouse pancreatic islets.
Journal: Biochemical pharmacology 20011001
Title: Diabetogenic effect of cyclosporin A is mediated by interference with mitochondrial function of pancreatic B-cells.
Journal: Molecular pharmacology 20011001
Title: Insulin activates ATP-sensitive K(+) channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway.
Journal: Diabetes 20011001
Title: Fasting glucose insulin ratio: a useful measure of insulin resistance in girls with premature adrenarche.
Journal: The Journal of clinical endocrinology and metabolism 20011001
Title: Molecular modelling and 1H-NMR: ultimate tools for the investigation of tolbutamide: beta-cyclodextrin and tolbutamide: hydroxypropyl-beta-cyclodextrin complexes.
Journal: Chemical & pharmaceutical bulletin 20011001
Title: The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity.
Journal: Clinical pharmacology and therapeutics 20011001
Title: Clinical relevance of genetic polymorphisms in the human CYP2C subfamily.
Journal: British journal of clinical pharmacology 20011001
Title: Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus.
Journal: Diabetologia 20011001
Title: Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods.
Journal: Diabetologia 20011001
Title: In vitro cytochrome P450-mediated hepatic activities for five substrates in specific pathogen free chickens.
Journal: Journal of veterinary pharmacology and therapeutics 20011001
Title: Mechanism-based inactivation of CYP2C11 by diclofenac.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010901
Title: Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells.
Journal: The Journal of pharmacology and experimental therapeutics 20010901
Title: Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia.
Journal: Brain : a journal of neurology 20010901
Title: Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw.
Journal: British journal of pharmacology 20010901
Title: Effect of Cirsium pascuarense on blood glucose levels of normoglycaemic and alloxan-diabetic mice.
Journal: Phytotherapy research : PTR 20010901
Title: Antidiabetic activity of the rhizoma of Anemarrhena asphodeloides and active components, mangiferin and its glucoside.
Journal: Biological & pharmaceutical bulletin 20010901
Title: An ATP-sensitive K(+) conductance in dissociated neurones from adult rat intracardiac ganglia.
Journal: The Journal of physiology 20010801
Title: Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression.
Journal: Pflugers Archiv : European journal of physiology 20010801
Title: The enhancement of glucose uptake caused by the collapse of gap junction communication is due to an increase in astrocyte proliferation.
Journal: Journal of neurochemistry 20010801
Title: Platelet-derived growth factor-BB: a survival factor for the retinal microvasculature during periods of metabolic compromise.
Journal: Current eye research 20010801
Title: Swelling-induced changes in cytosolic [Ca2++] in insulin-secreting cells: a role in regulatory volume decrease?
Journal: Molecular and cellular endocrinology 20010705
Title: In vivo effect of clarithromycin on multiple cytochrome P450s.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010701
Title: Longitudinal changes in body fat in African American and Caucasian children: influence of fasting insulin and insulin sensitivity.
Journal: The Journal of clinical endocrinology and metabolism 20010701
Title: Influence of the preparation method on the physicochemical properties of tolbutamide/cyclodextrin binary systems.
Journal: Drug development and industrial pharmacy 20010701
Title: The potential of small-scale fusion experiments and the Gordon-Taylor equation to predict the suitability of drug/polymer blends for melt extrusion.
Journal: Drug development and industrial pharmacy 20010701
Title: Establishment of the transformants expressing human cytochrome P450 subtypes in HepG2, and their applications on drug metabolism and toxicology.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20010601
Title: Tolbutamide stimulation of pancreatic beta-cells involves both cell recruitment and increase in the individual Ca(2+) response.
Journal: British journal of pharmacology 20010601
Title: Free radical-mediated tolbutamide desensitization of K+ATP channels in rat pancreatic beta-cells.
Journal: Endocrine journal 20010601
Title: A comparison of aroclor 1254-induced and uninduced rat liver microsomes to human liver microsomes in phenytoin O-deethylation, coumarin 7-hydroxylation, tolbutamide 4-hydroxylation, S-mephenytoin 4'-hydroxylation, chloroxazone 6-hydroxylation and testosterone 6beta-hydroxylation.
Journal: Chemico-biological interactions 20010516
Title: Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets.
Journal: Endocrinology 20010501
Title: Involvement of calmodulin in glucagon-like peptide 1(7-36) amide-induced inhibition of the ATP-sensitive K+ channel in mouse pancreatic beta-cells.
Journal: Experimental physiology 20010501
Title: Characterization of biotransformation enzyme activities in primary rat proximal tubular cells.
Journal: Chemico-biological interactions 20010416
Title: Isolation of the components of a complex mixture by means of column switching for their enhanced detection by mass spectrometry.
Journal: Journal of chromatography. A 20010413
Title: Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel.
Journal: British journal of pharmacology 20010401
Title: ION-pair liquid chromatography technique for the estimation of metformin in its multicomponent dosage forms.
Journal: Journal of pharmaceutical and biomedical analysis 20010401
Title: Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?
Journal: Diabetes 20010401
Title: Changes in the dissolution of tolbutamide by a traditional Chinese medicine, Sho-saiko-to (Xiao Chaihu Tang).
Journal: Biological & pharmaceutical bulletin 20010401
Title: WY-14,643 and other agonists of the peroxisome proliferator-activated receptor reveal a new mode of action for salicylic acid in soybean disease resistance.
Journal: Planta 20010401
Title: Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
Journal: European journal of clinical pharmacology 20010401
Title: Gi2 proteins couple somatostatin receptors to low-conductance K+ channels in rat pancreatic alpha-cells.
Journal: Pflugers Archiv : European journal of physiology 20010401
Title: The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.
Journal: Pflugers Archiv : European journal of physiology 20010401
Title: Effect of leptin on insulin, glugacon and somatostatin secretion in the perfused rat pancreas.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010401
Title: Interaction of sulfonylurea-conjugated polymer with insulinoma cell line of MIN6 and its effect on insulin secretion.
Journal: Journal of biomedical materials research 20010401
Title: Effects of vitamins and common drugs on reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rat microsomes.
Journal: Archives of physiology and biochemistry 20010401
Title: Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin.
Journal: International journal of pharmaceutics 20010314
Title: Variables in human liver microsome preparation: impact on the kinetics of l-alpha-acetylmethadol (LAAM) n-demethylation and dextromethorphan O-demethylation.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010301
Title: Interaction of stilbene disulphonates with cloned K(ATP) channels.
Journal: British journal of pharmacology 20010301
Title: Specific desensitization of sulfonylurea- but not imidazoline-induced insulin release after prolonged tolbutamide exposure.
Journal: Biochemical pharmacology 20010301
Title: Measurements of cytoplasmic Ca2+ in islet cell clusters show that glucose rapidly recruits beta-cells and gradually increases the individual cell response.
Journal: Diabetes 20010301
Title: Characterization of secretory and morphologic properties of primary cultured endocrine cells from porcine pancreata.
Journal: Pancreas 20010301
Title: Protein kinase C-dependent and -independent inhibition of Ca(2+) influx by phorbol ester in rat pancreatic beta-cells.
Journal: Cellular signalling 20010301
Title: Role of common sequence variants in insulin secretion in familial type 2 diabetic kindreds: the sulfonylurea receptor, glucokinase, and hepatocyte nuclear factor 1alpha genes.
Journal: Diabetes care 20010301
Title: Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers.
Journal: The Journal of pharmacy and pharmacology 20010301
Title: Inhibition of human CYP1A2 activity in vitro by methylxanthines: potent competitive inhibition by 8-phenyltheophylline.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010301
Title: Hypoglycemic effect of Hibiscus rosa sinensis L. leaf extract in glucose and streptozotocin induced hyperglycemic rats.
Journal: Indian journal of experimental biology 20010301
Title: Interindividual variations in levels and activities of cytochrome P-450 in liver microsomes of Chinese subjects.
Journal: Acta pharmacologica Sinica 20010301
Title: Activation of Na(+), K(+), Cl(-)-cotransport mediates intracellular Ca(2+) increase and apoptosis induced by Pinacidil in HepG2 human hepatoblastoma cells.
Journal: Biochemical and biophysical research communications 20010223
Title: The sulphonylurea glibenclamide inhibits multidrug resistance protein (MRP1) activity in human lung cancer cells.
Journal: British journal of pharmacology 20010201
Title: Effects of organic solvents on the activities of cytochrome P450 isoforms, UDP-dependent glucuronyl transferase, and phenol sulfotransferase in human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010201
Title: Effects of sho-saiko-to (xiao chai hu tang), a Chinese traditional medicine, on the gastric function and absorption of tolbutamide in rats.
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010201
Title: Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations.
Journal: Diabetes 20010201
Title: Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.
Journal: Diabetes 20010201
Title: Persistent hypoglycemia is induced by tolbutamide administration in broiler chickens fed a low-carbohydrate diet.
Journal: Domestic animal endocrinology 20010201
Title: Direct cytoplasmic CA(2+) responses to gastrin-releasing peptide in single beta cells.
Journal: Biochemical and biophysical research communications 20010126
Title: Mitochondrial priming modifies Ca2+ oscillations and insulin secretion in pancreatic islets.
Journal: The Biochemical journal 20010115
Title: Leptin administration improves skeletal muscle insulin responsiveness in diet-induced insulin-resistant rats.
Journal: American journal of physiology. Endocrinology and metabolism 20010101
Title: Inhibition of protein synthesis sequentially impairs distinct steps of stimulus-secretion coupling in pancreatic beta cells.
Journal: Endocrinology 20010101
Title: Activation of potassium conductance by ophiopogonin-D in acutely dissociated rat paratracheal neurones.
Journal: British journal of pharmacology 20010101
Title: Fluvoxamine inhibits the CYP2C9 catalyzed biotransformation of tolbutamide.
Journal: Clinical pharmacology and therapeutics 20010101
Title: Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors.
Journal: Journal of clinical pharmacology 20010101
Title: Is diclofenac a valuable CYP2C9 probe in humans?
Journal: European journal of clinical pharmacology 20010101
Title: Inhibition of drug metabolism in human liver microsomes by nizatidine, cimetidine and omeprazole.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010101
Title: High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. VI. Simultaneous evaluation of inhibition potential of drugs on human hepatic isozymes CYP2A6, 3A4, 2C9, 2D6 and 2E1.
Journal: Rapid communications in mass spectrometry : RCM 20010101
Title: Clinical pharmacokinetics of fluvastatin.
Journal: Clinical pharmacokinetics 20010101
Title: Drug interactions with irbesartan.
Journal: Clinical pharmacokinetics 20010101
Title: Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channels.
Journal: BMC pharmacology 20010101
Title: Effects of nicorandil administration on survival rate and arrhythmias during reperfusion in anesthetized rabbits.
Journal: Pharmacology 20010101
Title: Effects of CYP2C19 genotype and CYP2C9 on fluoxetine N-demethylation in human liver microsomes.
Journal: Acta pharmacologica Sinica 20010101
Title: Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs.
Journal: BMC pharmacology 20010101
Title: Effectiveness of nateglinide on in vitro insulin secretion from rat pancreatic islets desensitized to sulfonylureas.
Journal: International journal of experimental diabetes research 20010101
Title: In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6.
Journal: British journal of clinical pharmacology 20000401
Title: Stimulation of tolbutamide hydroxylation by acetone and acetonitrile in human liver microsomes and in a cytochrome P-450 2C9-reconstituted system.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20000101
Title: Multiple sites of purinergic control of insulin secretion in mouse pancreatic beta-cells.
Journal: Diabetes 19991101
Title: The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells.
Journal: Journal of molecular endocrinology 19990401
Title: Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons.
Journal: The EMBO journal 19990215
Title: Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele.
Journal: Pharmacogenetics 19990201
Title: Role of sympathetic nervous system in experimental hypertension and diabetes mellitus.
Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 19990101
Title: Pharmacological intervention: the antidiabetic approach.
Journal: European journal of clinical investigation 19980901
Title: Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.
Journal: Diabetes 19980401
Title: Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes.
Journal: The Journal of pharmacology and experimental therapeutics 19980201
Title: Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 19980201
Title: Pulsatile insulin release from pancreatic islets with nonoscillatory elevation of cytoplasmic Ca2+.
Journal: The Journal of clinical investigation 19971115
Title: Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations.
Journal: Pharmacogenetics 19970401
Title: Amino acid polymorphisms in the ATP-regulatable inward rectifier Kir6.2 and their relationships to glucose- and tolbutamide-induced insulin secretion, the insulin sensitivity index, and NIDDM.
Journal: Diabetes 19970301
Title: Allelic and functional variability of cytochrome P4502C9.
Journal: Pharmacogenetics 19970201
Title: Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 19961201
Title: A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.
Journal: The Journal of biological chemistry 19961004
Title: Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 19960701
Title: Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.
Journal: Science (New York, N.Y.) 19951117
Title: Successful treatment of severe refractory sulfonylurea-induced hypoglycemia with octreotide.
Journal: Diabetes care 19930101
Title: Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9.
Journal: Biochemical and biophysical research communications 19910329
Title: Pharmacological studies with the alpha 2-adrenoceptor antagonist midaglizole. Part I: Respiratory and cardiovascular systems.
Journal: Arzneimittel-Forschung 19910101
Title: Tolbutamide hydroxylation by human, rabbit and rat liver microsomes and by purified forms of cytochrome P-450.
Journal: Drug metabolism and disposition: the biological fate of chemicals 19900101
Title: Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: effect of chronic insulin and tolbutamide treatment.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19891001
Title: In-vivo effects of itraconazole on hepatic mixed-function oxidase.
Journal: The Journal of antimicrobial chemotherapy 19880201
Title: Effects of sulfonylurea compounds on Pneumocystis carinii.
Journal: The Journal of infectious diseases 19860501
Title: Reduction of the severity of nephropathy in aging Fischer 344 rats treated with analogs of arylsulfonyluria.
Journal: Toxicology and applied pharmacology 19790701
Title: Clonidine effect on insulin secretion and lipolysis in man.
Journal: Acta diabetologica latina 19780101
Title: Effects of prolonged tolbutamide treatment on plasma glucose concentrations and isoproterenol-induced cardiac lesions in rats.
Journal: Toxicology and applied pharmacology 19771001
Title: Encephalopathy induced by oral hypoglycemic drugs.
Journal: Archives of internal medicine 19770801
Title: Tolbutamide-induced hemolytic anemia.
Journal: Diabetes 19770201
Title: Oral hypoglycaemics in diabetes mellitus.
Journal: Lancet (London, England) 19750913
Title: Oral hypoglycaemic agents and cardiovascular complications of diabetes. Effect of long-term administration of tolbutamide and phenformin on the metabolism of glycosaminoglycans in normal rats.
Journal: Atherosclerosis 19730101
Title: [Autoimmune hemolytic anemia following alpha-methyldopa therapy].
Journal: Deutsche medizinische Wochenschrift (1946) 19681220
Title: [Recurrent hypoglycemic coma due to abnormal degradation of tolbutamide].
Journal: Deutsche medizinische Wochenschrift (1946) 19680315
Title: [Cytopenias caused by hypoglycemic sulfonamides].
Journal: Journees annuelles de diabetologie de l'Hotel-Dieu 19680101
Title: Nephrotic syndrome caused by probenecid.
Journal: JAMA 19670102
Title: Wray, H.L. and A.W. Harris, Adenosine 3', 5'-monophosphate-dependent protein kinase in adipose tissue: inhibition by tolbutamide. Biochem Biophys Res Commun, 1973. 53(1): p. 291-4.
Title: Sanchez-Alvarez, R., et al., Tolbutamide reduces glioma cell proliferation by increasing connexin43, which promotes the up-regulation of p21 and p27 and subsequent changes in retinoblastoma phosphorylation. Glia, 2006. 54(2): p. 125-34.
