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68-42-8,MFCD00067598
Catalog No.:AA00FA2G

68-42-8 | TETRAHYDROCORTICOSTERONE

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10mg
97%
in stock  
$440.00   $308.00
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25mg
97%
in stock  
$822.00   $575.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FA2G
Chemical Name:
TETRAHYDROCORTICOSTERONE
CAS Number:
68-42-8
Molecular Formula:
C21H34O4
Molecular Weight:
350.4923
MDL Number:
MFCD00067598
SMILES:
OCC(=O)[C@H]1CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CC[C@H]2[C@]1(C)CC[C@H](C2)O
Properties
Computed Properties
 
Complexity:
548  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
2.9  

Literature

Title: Urinary steroid profile in early pregnancy after in vitro fertilization.

Journal: Acta obstetricia et gynecologica Scandinavica 20120501

Title: 5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects.

Journal: British journal of pharmacology 20111101

Title: Recognition of 5α-reductase-2 deficiency in an adult female 46XY DSD clinic.

Journal: European journal of endocrinology 20110601

Title: Urine metabolomics analysis for adrenal incidentaloma activity detection and biomarker discovery.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110215

Title: Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma.

Journal: BMC cancer 20110101

Title: Finasteride-induced depression: new insights into possible pathomechanisms.

Journal: Journal of cosmetic dermatology 20101201

Title: Comparing plasma and faecal measures of steroid hormones in Adelie penguins Pygoscelis adeliae.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100101

Title: The urinary steroid profile in patients diagnosed with adrenal incidentaloma.

Journal: Clinical biochemistry 20090401

Title: A novel CYP11B2 gene mutation in an Asian family with aldosterone synthase deficiency.

Journal: The Journal of clinical endocrinology and metabolism 20090301

Title: The corticosteroid metabolic profile of the mouse.

Journal: Steroids 20081001

Title: Studies on neurosteroids XXIII. Analysis of tetrahydrocorticosterone isomers in the brain of rats exposed to immobilization using LC-MS.

Journal: Steroids 20071101

Title: Metabolomic approach to evaluate the toxicological effects of nonylphenol with rat urine.

Journal: Analytical chemistry 20070815

Title: Cellular distribution of the GABAA receptor-modulating 3alpha-hydroxy, 5alpha-reduced pregnane steroids in the adult rat brain.

Journal: Journal of neuroendocrinology 20070401

Title: Identification of plasma glucocorticoids in pallid sturgeon in response to stress.

Journal: General and comparative endocrinology 20070101

Title: The anxiolytic effect of pregnancy in rats is reversed by finasteride.

Journal: Pharmacology, biochemistry, and behavior 20061101

Title: Suppression of adrenal function by low-dose prednisone: assessment with 24-hour urinary steroid hormone profiles--a review of five cases.

Journal: Alternative medicine review : a journal of clinical therapeutic 20060301

Title: A neuroactive steroid inhibits guinea pig airway sensory nerves via Maxi-K channel activation.

Journal: International archives of allergy and immunology 20060101

Title: A neuroactive steroid, allotetrahydrocorticosterone inhibits sensory nerves activation in guinea-pig airways.

Journal: Neuroscience research 20051001

Title: Effect of neurosteroids on the retinal gabaergic system and electroretinographic activity in the golden hamster.

Journal: Journal of neurochemistry 20050901

Title: Urinary steroid metabolites and 11beta-hydroxysteroid dehydrogenase activity in patients with unipolar recurrent major depression.

Journal: Journal of affective disorders 20040701

Title: Insight into the mechanism of action of neuroactive steroids.

Journal: Molecular pharmacology 20040701

Title: An unusual case of Cushing's syndrome due to ACTH-independent macronodular adrenal hyperplasia.

Journal: Chirurgia italiana 20030101

Title: Salt-sensitivity of blood pressure and decreased 11beta-hydroxysteroid dehydrogenase type 2 activity after renal transplantation.

Journal: Transplantation 20020715

Title: Reduced 11beta-hydroxysteroid dehydrogenase activity in experimental nephrotic syndrome.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020501

Title: Neuroactive steroid-serotonergic interaction: responses to an intravenous L-tryptophan challenge in women with premenstrual syndrome.

Journal: European journal of endocrinology 20010701

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Tags:68-42-8 Molecular Formula|68-42-8 MDL|68-42-8 SMILES|68-42-8 TETRAHYDROCORTICOSTERONE