Home Other Building Blocks 72957-38-1
72957-38-1,MFCD00076366
Catalog No.:AA01E9SA

72957-38-1 | Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$184.00   $129.00
- +
5mg
98%
1 week  
$336.00   $235.00
- +
10mg
98%
1 week  
$508.00   $355.00
- +
25mg
98%
1 week  
$984.00   $689.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01E9SA
Chemical Name:
Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
CAS Number:
72957-38-1
Molecular Formula:
C75H126N24O15
Molecular Weight:
1603.9547
MDL Number:
MFCD00076366
SMILES:
NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCCN)CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)O)N)CC(C)C)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N
Properties
Computed Properties
 
Complexity:
3160  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
12  
Heavy Atom Count:
114  
Hydrogen Bond Acceptor Count:
21  
Hydrogen Bond Donor Count:
22  
Rotatable Bond Count:
54  
XLogP3:
-4.2  

Literature

Title: Controlling charge states of peptides through inductive electrospray ionization mass spectrometry.

Journal: Analytical chemistry 20111201

Title: Oxytocin in the periaqueductal gray participates in pain modulation in the rat by influencing endogenous opiate peptides.

Journal: Peptides 20110601

Title: Morphine-induced conditioned place preference in rats is inhibited by electroacupuncture at 2 Hz: role of enkephalin in the nucleus accumbens.

Journal: Neuropharmacology 20100101

Title: Lack of tolerance and morphine-induced cross-tolerance to the analgesia of chimeric peptide of Met-enkephalin and FMRFa.

Journal: Peptides 20081201

Title: Development of potent and selective phosphinic peptide inhibitors of angiotensin-converting enzyme 2.

Journal: Journal of medicinal chemistry 20080410

Title: Central reinforcing effects of ethanol are blocked by catalase inhibition.

Journal: Alcohol (Fayetteville, N.Y.) 20071101

Title: Influence of acute and chronic treadmill exercise on rat plasma lactate and brain NPY, L-ENK, DYN A1-13.

Journal: Cellular and molecular neurobiology 20070201

Title: Conformational analysis of dynorphin A (1-13) using hydrogen-deuterium exchange and tandem mass spectrometry.

Journal: European journal of mass spectrometry (Chichester, England) 20070101

Title: Vasorelaxing effect of U50,488H in pulmonary artery and underlying mechanism in rats.

Journal: Life sciences 20060418

Title: Through central arginine vasopressin, not oxytocin and endogenous opiate peptides, glutamate sodium induces hypothalamic paraventricular nucleus enhancing acupuncture analgesia in the rat.

Journal: Neuroscience research 20060101

Title: A Phase II, multicenter, randomized, double-blind, placebo-controlled crossover study of CJC-1008--a long-acting, parenteral opioid analgesic--in the treatment of postherpetic neuralgia.

Journal: Journal of opioid management 20060101

Title: New tris-alkoxycarbonyl arginine derivatives for peptide synthesis.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20050101

Title: Metabolism of dynorphin A(1-13).

Journal: Die Pharmazie 20040501

Title: Aggression and the three opioid families (endorphins, enkephalins, and dynorphins) in mice.

Journal: Behavior genetics 20030901

Title: Dynorphin and the hypothalamo-pituitary-adrenal axis during fetal development.

Journal: Life sciences 20030627

Title: [Changes of dynorphinA1-13 on the treatment of hypoxic-ischemic brain injury by the brain-derived neurotrophic factor in neonatal rats].

Journal: Zhonghua yi xue za zhi 20021210

Title: Sodium channel blocking actions of the kappa-opioid receptor agonist U50,488 contribute to its visceral antinociceptive effects.

Journal: Journal of neurophysiology 20020301

Title: [Effect of opioid peptides on the repair regeneration of the bone tissue].

Journal: Arkhiv patologii 20020101

Title: Activation of peripheral kappa opioid receptors inhibits capsaicin-induced thermal nociception in rhesus monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 19990401

Title: Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions.

Journal: The Journal of pharmacology and experimental therapeutics 19990101

Title: Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum.

Journal: British journal of pharmacology 19971001

Title: Dynorphin A-(1-13) potently improves scopolamine-induced impairment of passive avoidance response in mice.

Journal: European journal of pharmacology 19950214

Title: Dynorphin A (1-13) in the brain suppresses epinephrine-induced ventricular premature complexes and ventricular tachyarrhythmias.

Journal: Regulatory peptides 19920922

Title: [The role of the opiate mechanisms of the hippocampus and substantia nigra in the behavioral and convulsive disorders in picrotoxin-induced kindling].

Journal: Biulleten' eksperimental'noi biologii i meditsiny 19910301

Title: Effects of dynorphin A(1-13) and of fragments of beta-endorphin on blood pressure and heart rate of anesthetized rats.

Journal: Canadian journal of physiology and pharmacology 19910301

Title: Possible involvement of beta endorphin(1-31) and dynorphin(1-13) in the central hypotensive mechanism of action of alpha methyldopa.

Journal: Neuroendocrinology 19890101

Title: Cardiovascular effects of dynorphin A (1-13) in conscious rats and its modulation of morphine bradycardia over time.

Journal: Peptides 19870101

Title: Sensitivity to morphine-evoked bradycardia in rats is modified by dynorphin (1-13), Leu- and Met-enkephalin.

Journal: The Journal of pharmacology and experimental therapeutics 19840501

Title: Effect of dynorphin-(1-13) and related peptides on respiratory rate and morphine-induced respiratory rate depression.

Journal: European journal of pharmacology 19831209

Title: Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:72957-38-1 Molecular Formula|72957-38-1 MDL|72957-38-1 SMILES|72957-38-1 Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH