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76252-06-7,MFCD00865522
Catalog No.:AA00G6VV

76252-06-7 | Nicainoprol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$134.00   $94.00
- +
5mg
97%
in stock  
$341.00   $239.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00G6VV
Chemical Name:
Nicainoprol
CAS Number:
76252-06-7
Molecular Formula:
C21H27N3O3
Molecular Weight:
369.4574
MDL Number:
MFCD00865522
SMILES:
OC(COc1cccc2c1N(CCC2)C(=O)c1cccnc1)CNC(C)C
Properties
Computed Properties
 
Complexity:
474  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.6  

Downstream Synthesis Route
1-nicotinoyl-8-hydroxy-1,2,3,4-tetrahydroquinoline 
  865-47-4    106-89-8    76252-06-7 

[1]Patent:US4335123,1982,A

Literature

Title: Cardiac arrhythmias are ameliorated by local inhibition of angiotensin formation and bradykinin degradation with the converting-enzyme inhibitor ramipril.

Journal: Cardiovascular drugs and therapy 19891201

Title: Linz W, et al. Cardiac arrhythmias are ameliorated by local inhibition of angiotensin formation and bradykinin degradation with the converting-enzyme inhibitor ramipril. Cardiovasc Drugs Ther. 1989 Dec;3(6):873-82.

Title: Martorana PA, et al. Effects of nicainoprol on reperfusion arrhythmia in the isolated working rat heart and on ischemia and reperfusion arrhythmia and myocardial infarct size in the anesthetized rat. Eur J Pharmacol. 1987 Nov 17;143(3):391-401.

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