Home Other Building Blocks 86401-95-8
86401-95-8,MFCD00866150
Catalog No.:AA00IDYX

86401-95-8 | Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6a,11b)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$525.00   $368.00
- +
250mg
95%
in stock  
$1,000.00   $700.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IDYX
Chemical Name:
Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6a,11b)-
CAS Number:
86401-95-8
Molecular Formula:
C27H36O7
Molecular Weight:
472.5705
MDL Number:
MFCD00866150
SMILES:
CCC(=O)O[C@@]1(CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)C)C(=O)COC(=O)C
Properties
Computed Properties
 
Complexity:
980  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
3.8  

Literature

Title: Effective use of methylprednisolone aceponate 0.1% in a 9-month-old infant with atopic eczema and sleep disturbance.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20121101

Title: Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial.

Journal: Actas dermo-sifiliograficas 20120901

Title: A case of bullous pemphigoid in infancy treated with local corticosteroids.

Journal: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20111201

Title: Optimizing the treatment of atopic dermatitis in children: a review of the benefit/risk ratio of methylprednisolone aceponate.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20110501

Title: Segmental lichen aureus: a report of two cases treated with methylprednisolone aceponate.

Journal: The Australasian journal of dermatology 20110501

Title: Balancing efficacy and safety in the management of atopic dermatitis: the role of methylprednisolone aceponate.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20110301

Title: Efficacy and tolerability of proactive treatment with topical corticosteroids and calcineurin inhibitors for atopic eczema: systematic review and meta-analysis of randomized controlled trials.

Journal: The British journal of dermatology 20110201

Title: Beneficial effects of pseudoceramide-containing physiologic lipid mixture as a vehicle for topical steroids.

Journal: European journal of dermatology : EJD 20110101

Title: Annular lichenoid dermatitis.

Journal: Clinical and experimental dermatology 20101201

Title: Evaluation of methylprednisolone aceponate, tacrolimus and combination thereof in the psoriasis plaque test using sum score, 20-MHz-ultrasonography and optical coherence tomography.

Journal: International journal of clinical pharmacology and therapeutics 20101201

Title: [Allergic contact dermatitis and systemic contact dermatitis in a patient with polysensitization to topical corticosteroids].

Journal: Actas dermo-sifiliograficas 20091101

Title: [Advantan for therapy of atopic dermatitis].

Journal: Georgian medical news 20090601

Title: Pimecrolimus 1% cream, methylprednisolone aceponate 0.1% cream and metronidazole 0.75% gel in the treatment of seborrhoeic dermatitis: a randomized clinical study.

Journal: The Journal of dermatological treatment 20090101

Title: Reduction of relapses of atopic dermatitis with methylprednisolone aceponate cream twice weekly in addition to maintenance treatment with emollient: a multicentre, randomized, double-blind, controlled study.

Journal: The British journal of dermatology 20080401

Title: Superior nuclear receptor selectivity and therapeutic index of methylprednisolone aceponate versus mometasone furoate.

Journal: Experimental dermatology 20070901

Title: Efficacy and safety of methylprednisolone aceponate ointment 0.1% compared to tacrolimus 0.03% in children and adolescents with an acute flare of severe atopic dermatitis.

Journal: Allergy 20070201

Title: Methylprednisolone aceponate in eczema and other inflammatory skin disorders -- a clinical update.

Journal: International journal of clinical practice 20060101

Title: [Comparative effectiveness of 0.1% metilprednisolone aceponate and 0.05% betamethasone dipropionate among children with nonretractable prepuce].

Journal: Gaceta medica de Mexico 20060101

Title: Allergic contact dermatitis caused by 6alpha-methylprednisolone aceponate.

Journal: Contact dermatitis 20050701

Title: Phase solubility and structure of the inclusion complexes of prednisolone and 6 alpha-methyl prednisolone with various cyclodextrins.

Journal: Journal of pharmaceutical sciences 20050301

Title: [Interleukin-6 as a marker of the activity of a pathological process in patients with psoriasis].

Journal: Likars'ka sprava 20050101

Title: Allergic contact dermatitis to methylprednisolone aceponate in a topical corticosteroid.

Journal: The Australasian journal of dermatology 20040801

Title: Contact allergy to various ingredients of topical medicaments.

Journal: Contact dermatitis 20030701

Title: Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study.

Journal: The British journal of dermatology 20020601

Title: Multiple corticosteroid allergies.

Journal: The Australasian journal of dermatology 20010201

Title: Comparison of the local and systemic side effects of methylprednisolone aceponate and mometasone furoate applied as ointments with equal antiinflammatory activity.

Journal: Journal of the American Academy of Dermatology 19931001

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:86401-95-8 Molecular Formula|86401-95-8 MDL|86401-95-8 SMILES|86401-95-8 Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6a,11b)-