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Home Other Building Blocks 920014-72-8
920014-72-8,MFCD30532719
Catalog No.:AA01EO7V

920014-72-8 | Setmelanotide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98.85%(LCMS)
2 weeks  
$554.00   $388.00
- +
10mg
98.85%(LCMS)
2 weeks  
$783.00   $548.00
- +
25mg
98.85%(LCMS)
2 weeks  
$1,299.00   $909.00
- +
100mg
98
2 weeks  
$1,568.00   $1,098.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO7V
Chemical Name:
Setmelanotide
CAS Number:
920014-72-8
Molecular Formula:
C49H68N18O9S2
Molecular Weight:
1117.3094
MDL Number:
MFCD30532719
SMILES:
NC(=N)NCCC[C@@H](C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC1=O)C)Cc1[nH]cnc1)Cc1ccccc1)CCCNC(=N)N)Cc1c[nH]c2c1cccc2)C(=O)N)NC(=O)C
Properties
Computed Properties
 
Complexity:
2130  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
78  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
15  
Rotatable Bond Count:
18  
XLogP3:
-2.5  

Literature

Title: RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.

Journal: The Journal of clinical endocrinology and metabolism 20150401

Title: The melanocortin-4 receptor as target for obesity treatment: a systematic review of emerging pharmacological therapeutic options.

Journal: International journal of obesity (2005) 20140201

Title: Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques.

Journal: Diabetes 20130201

Title: Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL/6J mice.

Journal: Peptides 20091001

Title: Mutations in ligands and receptors of the leptin-melanocortin pathway that lead to obesity.

Journal: Nature clinical practice. Endocrinology & metabolism 20081001

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SDS
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