Title: An isolable acyclic hemiacetal of ansamitocin P-3.
Journal: Magnetic resonance in chemistry : MRC 20120301
Title: The interplay between mutasynthesis and semisynthesis: generation and evaluation of an ansamitocin library.
Journal: Angewandte Chemie (International ed. in English) 20120116
Title: Combined muta- and semisynthesis: a powerful synthetic hybrid approach to access target specific antitumor agents based on ansamitocin P3.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120116
Title: Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis.
Journal: Chemistry & biology 20111223
Title: Enhanced production of ansamitocin P-3 by addition of Mg2+ in fermentation of Actinosynnema pretiosum.
Journal: Bioresource technology 20111101
Title: N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis.
Journal: Chembiochem : a European journal of chemical biology 20110725
Title: Mutational biosynthesis of ansamitocin antibiotics: a diversity-oriented approach to exploit biosynthetic flexibility.
Journal: Chembiochem : a European journal of chemical biology 20110307
Title: Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum.
Journal: Bioresource technology 20110101
Title: Cyclization of synthetic seco-proansamitocins to ansamitocin macrolactams by Actinosynnema pretiosum as biocatalyst.
Journal: Chembiochem : a European journal of chemical biology 20101210
Title: A new antitumour ansamitocin from Actinosynnema pretiosum.
Journal: Natural product research 20100701
Title: Preparative isolation and purification of anti-tumor agent ansamitocin P-3 from fermentation broth of Actinosynnema pretiosum using high-performance counter-current chromatography.
Journal: Journal of separation science 20100501
Title: Constitutive overexpression of asm2 and asm39 increases AP-3 production in the actinomycete Actinosynnema pretiosum.
Journal: Journal of industrial microbiology & biotechnology 20091101
Title: Timing of the Delta(10,12)-Delta(11,13) double bond migration during ansamitocin biosynthesis in Actinosynnema pretiosum.
Journal: Journal of the American Chemical Society 20090325
Title: Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins.
Journal: Chemistry & biology 20080825
Title: Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant.
Journal: Chembiochem : a European journal of chemical biology 20080505
Title: The ansacarbamitocins: polar ansamitocin derivatives.
Journal: Journal of natural products 20071001
Title: New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum.
Journal: Archives of pharmacal research 20070601
Title: An integrative expression vector for Actinosynnema pretiosum.
Journal: BMC biotechnology 20070101
Title: On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of 'glycolate' units into ansamitocin and soraphen A.
Journal: Journal of the American Chemical Society 20061108
Title: Determination of the cryptic stereochemistry of the first PKS chain-extension step in ansamitocin biosynthesis by Actinosynnema pretiosum.
Journal: Chembiochem : a European journal of chemical biology 20060801
Title: Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20050301
Title: An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics.
Journal: Journal of pharmaceutical and biomedical analysis 20041119
Title: A novel amide N-glycoside of ansamitocins from Actinosynnema pretiosum.
Journal: The Journal of antibiotics 20040501
Title: The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum.
Journal: Journal of the American Chemical Society 20031126
Title: Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate.
Journal: Journal of the American Chemical Society 20020612
Title: Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual 'glycolate' chain extension unit in ansamitocin biosynthesis.
Journal: Journal of the American Chemical Society 20020424
Title: Venghateri JB, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine site. PLoS One. 2013 Oct 4;8(10):e75182.