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912569-84-7
Catalog No.:AA01CB93

912569-84-7 | N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine

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Technical Information
Catalog Number:
AA01CB93
Chemical Name:
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
CAS Number:
912569-84-7
Molecular Formula:
C35H48ClN3O10S
Molecular Weight:
738.2877
SMILES:
SCCC(=O)N([C@H](C(=O)O[C@H]1CC(=O)N(C)c2cc(C/C(=C/C=C/[C@H]([C@]3(C[C@@H]([C@H]([C@H]4[C@@]1(C)O4)C)OC(=O)N3)O)OC)/C)cc(c2Cl)OC)C)C
Properties

Literature

Title: Lopus M, et al. Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules. Mol Cancer Ther. 2010 Oct;9(10):2689-99.

Title: Oroudjev E, et al. Maytansinoid-antibody conjugates induce mitotic arrest by suppressing microtubule dynamic instability. Mol Cancer Ther. 2010 Oct;9(10):2700-13.

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Tags:912569-84-7 Molecular Formula|912569-84-7 MDL|912569-84-7 SMILES|912569-84-7 N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine