Title: TCDD and omeprazole prime platelets through the aryl hydrocarbon receptor (AhR) non-genomic pathway.
Journal: Toxicology letters20150519
Title: Antioxidative properties of hydrogen sulfide may involve in its antiadhesive action on blood platelets.
Journal: Clinical biochemistry20121201
Title: The activation of protease-activated receptor 1 mediates proliferation and invasion of nasopharyngeal carcinoma cells.
Journal: Oncology reports20120701
Title: Thrombin stimulates integrin β1-dependent adhesion of human pancreatic cancer cells to vitronectin through protease-activated receptor (PAR)-1.
Journal: Hepato-gastroenterology20120101
Title: PKC inhibition markedly enhances Ca2+ signaling and phosphatidylserine exposure downstream of protease-activated receptor-1 but not protease-activated receptor-4 in human platelets.
Journal: Journal of thrombosis and haemostasis : JTH20110801
Title: Platelet function following trauma. A multiple electrode aggregometry study.
Journal: Thrombosis and haemostasis20110801
Title: Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn kinase.
Journal: The Journal of biological chemistry20110708
Title: The effect of intravenous high-dose methylprednisolone on platelet reactivity assessed with multiple electrode aggregometry.
Journal: Thrombosis and haemostasis20110601
Title: Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration. A randomised controlled trial.
Journal: Thrombosis and haemostasis20110401
Title: In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation.
Journal: Journal of thrombosis and haemostasis : JTH20110301
Title: Hemostatic function of buffy coat platelets in additive solution treated with pathogen reduction technology.
Journal: Transfusion20110201
Title: Measurement of platelet function in dogs using a novel impedance aggregometer.
Journal: Veterinary journal (London, England : 1997)20100801
Title: Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli.
Journal: Nature biotechnology20100701
Title: A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery.
Journal: Anesthesia and analgesia20100301
Title: Mild and moderate hypothermia increases platelet aggregation induced by various agonists: a whole blood in vitro study.
Journal: Platelets20100101
Title: Is TRAP-6 suitable as a positive control for platelet reactivity when assessing response to clopidogrel?
Journal: Platelets20100101
Title: Valproic acid and all trans retinoic acid differentially induce megakaryopoiesis and platelet-like particle formation from the megakaryoblastic cell line MEG-01.
Journal: Platelets20100101
Title: Preliminary evidence for a matrix metalloproteinase-2 (MMP-2)-dependent shedding of soluble CD40 ligand (sCD40L) from activated platelets.
Journal: Platelets20090901
Title: Proteinase-activated receptor-1 activation presynaptically enhances spontaneous glutamatergic excitatory transmission in adult rat substantia gelatinosa neurons.
Journal: Journal of neurophysiology20090701
Title: Protein kinase C-mediated phosphorylation and activation of PDE3A regulate cAMP levels in human platelets.
Journal: The Journal of biological chemistry20090501
Title: Impaired activation of platelets lacking protein kinase C-theta isoform.
Journal: Blood20090312
Title: Histone H3 as a novel substrate for MAP kinase phosphatase-1.
Journal: American journal of physiology. Cell physiology20090201
Title: The effect of ex vivo anticoagulants on whole blood platelet aggregation.
Journal: Platelets20090201
Title: Whole-blood aggregometry: are there any limits with regard to platelet counts?
Journal: Acta anaesthesiologica Scandinavica20090101
Title: Endothelium-derived hyperpolarizing factor mediated relaxations in pig coronary arteries do not involve Gi/o proteins.
Journal: Acta pharmacologica Sinica20081201
Title: Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment.
Journal: Integrative cancer therapies20081201
Title: Modulation of tissue factor and tissue factor pathway inhibitor-1 by neutrophil proteases.
Journal: Thrombosis and haemostasis20081201
Title: Coordinate activation of human platelet protease-activated receptor-1 and -4 in response to subnanomolar alpha-thrombin.
Journal: The Journal of biological chemistry20081003
Title: Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets.
Journal: Journal of thrombosis and haemostasis : JTH20080801
Title: The periodontal pathogen Porphyromonas gingivalis sensitises human blood platelets to epinephrine.
Journal: Platelets20080801
Title: The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.
Journal: The Journal of biological chemistry20080704
Title: Development of proteomic signatures of platelet activation using surface-enhanced laser desorption/ionization technology in a clinical setting.
Journal: American journal of clinical pathology20080601
Title: Delayed inhibition of agonist-induced granulocyte-platelet aggregation after low-dose sevoflurane inhalation in humans.
Journal: Anesthesia and analgesia20080601
Title: Multiple electrode aggregometry and P2Y(12) antagonists.
Journal: Thrombosis and haemostasis20080601
Title: Fluoxetine (Prozac) augments platelet activation mediated through protease-activated receptors.
Journal: Journal of thrombosis and haemostasis : JTH20080401
Title: Elevated platelet reactivity in stable angina pectoris without significant coronary flow obstruction.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.)20080201
Title: Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20080116
Title: VEGF and thrombin induce MKP-1 through distinct signaling pathways: role for MKP-1 in endothelial cell migration.
Journal: American journal of physiology. Cell physiology20080101
Title: Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.
Journal: Thrombosis and haemostasis20080101
Title: Regulation of protease-activated receptor (PAR) 1 and PAR4 signaling in human platelets by compartmentalized cyclic nucleotide actions.
Journal: The Journal of pharmacology and experimental therapeutics20070801
Title: Osteosarcoma cell-calcium signaling through tissue factor-factor VIIa complex and factor Xa.
Journal: FEBS letters20070612
Title: Platelets possess and require an active protein palmitoylation pathway for agonist-mediated activation and in vivo thrombus formation.
Journal: Arteriosclerosis, thrombosis, and vascular biology20070601
Title: Parnaparin, a low-molecular-weight heparin, prevents P-selectin-dependent formation of platelet-leukocyte aggregates in human whole blood.
Journal: Thrombosis and haemostasis20070601
Title: Adenosine opposes thrombin-induced inhibition of intercellular calcium wave in corneal endothelial cells.
Journal: Investigative ophthalmology & visual science20070401
Title: Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development.
Journal: Thrombosis and haemostasis20070301
Title: Ex vivo microvesicle formation after prolonged ischemia in renal transplantation.
Journal: Thrombosis research20070101
Title: [Activation of cardiac contractivity of the edible snail H. pomatia under effect of thrombin. Study of role of cAMP].
Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii20070101
Title: [Role of adenosine diphosphate in the course of thrombin signal transmission].
Journal: Zhonghua yi xue za zhi20061212
Title: PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]: evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets.
Journal: Journal of thrombosis and haemostasis : JTH20061201
Title: Platelet and monocyte activation by hyperglycemia and hyperinsulinemia in healthy subjects.
Journal: Platelets20061201
Title: Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood.
Journal: Thrombosis and haemostasis20061201
Title: Factor VIII is a positive regulator of platelet function.
Journal: Platelets20061101
Title: Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans.
Journal: Circulation20061010
Title: Comparison of the effects of PAR1 antagonists, PAR4 antagonists, and their combinations on thrombin-induced human platelet activation.
Journal: European journal of pharmacology20060928
Title: Do heterotrimeric G proteins redistribute upon G protein-coupled receptor stimulation in platelets?
Journal: Platelets20060901
Title: Galpha12/13- and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors.
Journal: Molecular pharmacology20060601
Title: ThromboFix platelet stabilizer: advances in clinical platelet analyses by flow cytometry?
Journal: Platelets20060601
Title: Actin polymerisation regulates thrombin-evoked Ca(2+) signalling after activation of PAR-4 but not PAR-1 in human platelets.
Journal: Platelets20060501
Title: The platelet receptor for type III collagen (TIIICBP) is present in platelet membrane lipid microdomains (rafts).
Journal: Histochemistry and cell biology20060401
Title: Fibrin sealant promotes migration and proliferation of human articular chondrocytes: possible involvement of thrombin and protease-activated receptors.
Journal: International journal of molecular medicine20060401
Title: Agonists-induced platelet activation varies considerably in healthy male individuals: studies by flow cytometry.
Journal: Annals of hematology20060201
Title: The influence of bromelain on platelet count and platelet activity in vitro.
Journal: Platelets20060201
Title: Development of a time-resolved immunofluorometric assay for quantifying platelet-derived microparticles in human plasma.
Journal: Thrombosis research20060101
Title: [Biodegradable microparticles with immobilized peptide for wound healing].
Journal: Biomeditsinskaia khimiia20060101
Title: The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion.
Journal: Blood20050515
Title: Coagulation factor Xa stimulates interleukin-8 release in endothelial cells and mononuclear leukocytes: implications in acute myocardial infarction.
Journal: Arteriosclerosis, thrombosis, and vascular biology20050201
Title: Inverse relationships between coronary blood flow obstruction and platelet reactivity in stable angina pectoris.
Journal: Platelets20050101
Title: alpha-thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78-kDa stress response protein(s) in lung fibroblast cells.
Journal: The Journal of biological chemistry20041119
Title: Signaling mechanisms involved in protease-activated receptor-1-mediated interleukin-6 production by human gingival fibroblasts.
Journal: The Journal of pharmacology and experimental therapeutics20041101
Title: Induction and antimicrobial activity of platelet basic protein derivatives in human monocytes.
Journal: Journal of leukocyte biology20041101
Title: Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1.
Journal: The Biochemical journal20040915
Title: Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses.
Journal: Blood20040901
Title: Variable hypocoagulant effect of fish oil intake in humans: modulation of fibrinogen level and thrombin generation.
Journal: Arteriosclerosis, thrombosis, and vascular biology20040901
Title: Effects of inhaled thrombin receptor agonists in mice.
Journal: British journal of pharmacology20040901
Title: The effect of ASA on platelet activation during apheresis and on in-vitro properties of stored platelet concentrates.
Journal: Transfusion20040901
Title: The effects of high molecular weight hydroxyethyl starch solutions on platelets.
Journal: Anesthesia and analgesia20040901
Title: Soluble CD40 ligand in pulmonary arterial hypertension: possible pathogenic role of the interaction between platelets and endothelial cells.
Journal: Circulation20040824
Title: Akt activation in platelets depends on Gi signaling pathways.
Journal: The Journal of biological chemistry20040206
Title: PAR1 antagonism protects against experimental liver fibrosis. Role of proteinase receptors in stellate cell activation.
Journal: Hepatology (Baltimore, Md.)20040201
Title: Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets.
Journal: The Journal of biological chemistry20040123
Title: The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolism.
Journal: Leukemia & lymphoma20030901
Title: High-affinity thrombin receptor (PAR-1) ligands: a new generation of indole-based peptide mimetic antagonists with a basic amine at the C-terminus.
Journal: Bioorganic & medicinal chemistry letters20030707
Title: Thrombin downregulates muscle acetylcholine receptors via an IP3 signaling pathway by activating its G-protein-coupled protease-activated receptor-1.
Journal: Journal of cellular physiology20030701
Title: Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin.
Journal: The Journal of physiology20030615
Title: Thrombin-induced Ca2+ mobilization in human gingival fibroblasts is mediated by protease-activated receptor-1 (PAR-1).
Journal: Life sciences20030606
Title: Interleukin-7-mediated inflammation in unstable angina: possible role of chemokines and platelets.
Journal: Circulation20030603
Title: Involvement of nitric oxide and tachykinins in the effects induced by protease-activated receptors in rat colon longitudinal muscle.
Journal: British journal of pharmacology20030601
Title: Effects of inhibition of P2Y(1) and P2Y(12) on whole blood clotting, coagulum elasticity and fibrinolysis resistance studied with free oscillation rheometry.
Journal: Thrombosis research20030315
Title: Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas.
Journal: Cancer20030201
Title: Platelet phosphatidylserine exposure and procoagulant activity in clotting whole blood--different effects of collagen, TRAP and calcium ionophore A23187.
Journal: Thrombosis and haemostasis20030101
Title: Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation.
Journal: The Biochemical journal20021201
Title: Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes.
Journal: Circulation research20020920
Title: Enhanced platelet aggregation with TRAP-6 and collagen in platelet aggregometry in patients with venous thromboembolism.
Journal: Thrombosis research20020915
Title: Selective inhibition of protease-activated receptor 4-dependent platelet activation by YD-3.
Journal: Thrombosis and haemostasis20020601
Title: Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling.
Journal: Blood20020515
Title: Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.
Journal: The Biochemical journal20020501
Title: Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome.
Journal: Thrombosis and haemostasis20020401
Title: Identification of functional VEGF receptors on human platelets.
Journal: FEBS letters20020213
Title: Participation of protease-activated receptor-1 in thrombin-induced microglial activation.
Journal: Journal of neurochemistry20020201
Title: Effect of halothane and isoflurane on binding of ADP- and TRAP-6- activated platelets to leukocytes in Whole blood.
Journal: Anesthesiology20020101
Title: [Polymer coatings with immobilized thrombin and peptides: preparation and use for wound healing].
Journal: Voprosy meditsinskoi khimii20020101
Title: Thrombin and PAR-1 activating peptide increase iNOS expression in cytokine-stimulated C6 glioma cells.
Journal: Journal of neurochemistry20011101
Title: Platelet aggregation is not initiated by platelet shape change.
Journal: Laboratory investigation; a journal of technical methods and pathology20011101
Title: [The role of PAR family receptors in activation of mast cells in the norm and in acute inflammation in rats].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova20011101
Title: Aprotinin: is it prothrombotic?
Journal: Perfusion20010901
Title: Pharmacodynamics and pharmacokinetics of eptifibatide in patients with acute coronary syndromes: prospective analysis from PURSUIT.
Journal: Circulation20010724
Title: Tritiated photoactivatable analogs of the native human thrombin receptor (PAR-1) agonist peptide, SFLLRN-NH2.
Journal: The journal of peptide research : official journal of the American Peptide Society20010601
Title: Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20010401
Title: Clinical application of procedural platelet monitoring during percutaneous coronary intervention among patients at increased bleeding risk.
Journal: Journal of thrombosis and thrombolysis20010401
Title: Systemic vascular effects of thrombin and thrombin receptor activating peptide in rats.
Journal: Thrombosis research20010315
Title: Platelet CD40 ligand (CD40L)--subcellular localization, regulation of expression, and inhibition by clopidogrel.
Journal: Platelets20010301
Title: Thrombin-stimulated growth, clustering, and collagen lattice contraction of human gingival fibroblasts is associated with its protease activity.
Journal: Journal of periodontology20010301
Title: The effects of stimulating protease-activated receptor-1 and -2 in A172 human glioblastoma.
Journal: Journal of neural transmission (Vienna, Austria : 1996)20010101
Title: Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets.
Journal: Blood20001215
Title: In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist.
Journal: European journal of pharmacology19991119
Title: Transcellular signaling and pharmacological modulation of thrombin-induced production of plasminogen activator inhibitor-1 in vascular smooth muscle cells.
Journal: Seminars in thrombosis and hemostasis19980101
Title: Expression of thrombin receptors in human atherosclerotic coronary arteries leads to an exaggerated vasoconstrictory response in vitro.
Journal: Journal of cardiovascular pharmacology19971101
Title: Thrombin stimulates wortmannin-inhibitable phosphoinositide 3-kinase and membrane blebbing in CHRF-288 cells.
Journal: The Biochemical journal19960315
Title: Kahn ML, et, al. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest. 1999 Mar;103(6):879-87.
Title: Kinlough-Rathbone RL, et, al. Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets. Blood. 1993 Jul 1;82(1):103-6.
Title: Chintala MS, et, al. Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats. Eur J Pharmacol. 1998 May 22;349(2-3):237-43.
