Noncryogenic Preparation of Functionalized Arylboronic Esters through a Magnesium-Iodine Exchange with in Situ Quench

Emilien Demory, Veronique Blandin, Jacques Einhorn, and Pierre Y. Chavant
Departement de Chimie Moleculaire, UMR-5250, ICMG FR-2607, CNRS, Universite Joseph Fourier, BP 53, 38041 Grenoble Cedex 09, France.

 

INTRODUCTION
Arylboronic acids and esters have found a prominent place in the synthetic chemist’s toolbox, the latter being often preferred for convenience in their purification and characterization and for their ability to be observed via gas or liquid chromatography. Despite the recent developments in transition metal-catalyzed borylation,1-4 the cheapest and most common way of synthesizing arylboronic acids and esters remains the reaction of an organolithium or organomagnesium intermediate with a trialkylborate at low temperature, typically -78 C (Li) up to -10 C (Mg).1,5 An attractive method in this context is the generation of the aryl Grignard reagent by metal-halogen exchange using reagents such as i PrMgBr or i PrMgCl 3 LiCl.6 Compared to the historic Grignard synthesis from Mg0, this procedure, introduced by Knochel and Cahiez,7 allows the preparation of the reagent at milder temperatures (-40 C to room temperature), which broadly enlarges the functional group compatibility: for instance,
arylmagnesium halides bearing ester or nitrile substituents become accessible. The exchange reaction is generally completed within hours, and the organomagnesium species can then be reacted with an electrophile at temperatures below 0 C, typically -30 to -10 C in the case of a trialkylborate.

 

The functionalized Grignard reagents are intrinsically unstable, even if they can be kept for several hours at low temperature.6a Furthermore, with the expanding use of this magnesium-halogen method for the preparation of arylmagnesium reagents, some concerns have been raised regarding the stability of the reaction mixture. Process safety evaluation studies9 revealed that an exothermic decomposition of the solution is possible—even for phenylmagnesium chloride—and that onset temperatures as low as 55 C can be found. The structure of the aromatic ring and the concentration of the solution have a strong influence on the severity of the event, fluorine substituents and concentrated media being detrimental. A solution to avoid the prolonged coexistence of the aryl Grignard reagent, reactive functional
groups, and i PrX, the byproduct of the magnesium-halogen exchange, would be to directly trap the reactive species by the electrophile in situ. Such a procedure has proven efficient in some cases with organolithium species and triisopropyl borate, but yields are still inadequate for challenging substrates such as ethyl p-bromobenzoate.10 Regarding the magnesium-halogen exchange reaction, scarce examples of in situ trapping with trialkylborates can be found, with varying degrees of success.11

 

Among boronic acid derivatives, arylboronic hexylene glycol esters emerged as interesting compounds. Murata’s team12 and ours13 have shown that they exhibit excellent stability toward air, water, and chromatography,14 and undergo Suzuki-Miyaura reactions with aryl iodides, bromides, and triflates in excellent yields. Advantageously, hexylene glycol—a solvent—is much less expensive than pinacol.15 We thus wondered whether 2-isopropoxy-4,4,6-trimethyl-1,3,2-dioxaborinane16 (MPBOi Pr, 1) could be an efficient in situ trapping agent for arylmagnesium species issuing from a magnesium-halogen exchange.

RESULTS AND DISCUSSION
Reagent 1 was easily prepared from boric acid, hexylene glycol, and isopropanol by azeotropic removal of water (see Experimental Section),17 and methyl 4-iodobenzoate 2a was chosen as the first substrate. The magnesium-iodine exchange reaction was carried out with in situ quench, at 0 C, through gradual addition of a THF solution of i PrMgCl 3 LiCl to the mixture of 1 and 2a in THF (Scheme 1).18

 

Monitoring the reaction by GC analysis showed that the transformation of 2a into arylboronic ester 3a was complete by the end of the addition. Hydrolysis of the reaction mixture led to a dramatically clean crude product19 and to the corresponding boronic ester in 77% isolated yield after a simple filtration over silica gel. This first result was very promising, given the competitive reactions at stake (Scheme 2): magnesium-iodine exchange, nucleophilic addition of the organomagnesium species onto the electrophilic MPBOi Pr20 or onto the carboxylic ester.6b Once the exchange has occurred, the aryl Grignard reagent does not accumulate but instantaneously reacts with 1 to give the arylboronic ester. Indeed, we did not detect any methyl benzoate by GC analysis of hydrolyzed aliquots sampled during the addition of i PrMgCl 3 LiCl. The selectivity in the case of 2a can be partly explained by the presence of the electron-withdrawing substituent, known to strongly accelerate the magnesium-halogen exchange.21 However, the nature of the halogen is crucial.

 

Indeed, in the case of aryl bromide 20 a, the exchange proved too slow22 compared to the nucleophilic addition onto 1, and methyl 4-bromobenzoate 20 a was recovered unchanged when submitted
to the protocol from Scheme 1. We then investigated the nature of the aryl iodides that could undergo the magnesium-iodine exchange in the presence of MPBOi Pr 1 (Scheme 3 and Table 1). The reaction proceeds smoothly with aryl iodides bearing electron-withdrawing reactive substituents such as ester and nitrile groups, leading to arylboronic hexylene glycol esters 3a-c in high yields (Table 1, entries 1-3).

 

The use of i PrMgCl 3 LiCl was not suitable for a nitro group and led to a complex mixture. PhMgCl is known to allow magnesiumiodine exchange in the presence of an o-nitro group, but to react on
a nitro group in meta- or para- position.23 In the present system, the only reaction that takes place is between PhMgCl and MPBOi Pr: a mixture of unreacted 1-iodo-3-nitrobenzene 2d and phenylboronic ester was obtained (Table 1, entry 4).

 

Starting from diiodobenzenes, the monoborylated products 3e-f are selectively obtained (Table 1, entries 5-6); traces (∼1%) of the diborylated compound were detected only in the case of the para disubstituted 2e, by 1 H NMR and GC analysis of the crude material.24 The borylation of o-halo iodobenzene occurs at the iodine position, and no product resulting from aryne formation25 could be detected (Table 1, entries 6-8).

 

Running the reaction at lower temperature slightly improved the yield in arylboronic ester 3f (Table 1, entry 6). The o-trifluoromethyl arylboronic ester 3i was prepared in quantitative yield up to a 100 mmol scale using only a slight excess (10 mol %) of reagents (Table 1, entry 9). This excellent result is particularly interesting as the corresponding aryl Grignard reagent is reported to be prone to a highly exothermic decomposition.9b The very clean crude product was engaged without further purification in a Suzuki-Miyaura coupling leading to biaryl 5 bearing electron-withdrawing substituents on both aryl rings in 80% unoptimised yield (Scheme 4).26 2-Pyridyl boronic acids are notoriously unstable, and ester derivatives are therefore attractive compounds;27 we were thus pleased to obtain 6 bromopyridin-2-yl boronic ester 3j in excellent yield (Table 1, entry 10).

 

Electron-donating substituents proved detrimental to the reaction: the slower rate of the magnesium-iodine exchange28 (constant k1 in Scheme 2) made the nucleophilic addition of the alkylmagnesium species onto 1 competitive. i PrMgCl 3 LiCl was consumed to give MPBi Pr and the conversion of aryl iodide 2 was therefore incomplete; no synthetically useful yield of arylboronic ester 3 could be obtained at 0 C (Table 1, entries 11-13).

 

As we can see from the above results, the electronic nature of the aryl iodide plays an important part in the outcome of the borylation, by modifying the rate constant k1 in Scheme 2. For a given aryl iodide, other parameters can favor the exchange reaction over the nucleophilic addition, by changing either the rate constants (k1, k2) or the reaction rates. To test the influence of the reaction conditions, we chose 2-iodoanisole as a borderline substrate for which k1 is close to k2; 29 some aryl iodide remained unreacted, and we used the conversion of 2m into arylboronic ester 3m as a measure of effectiveness (Scheme 5 and Table 2).

The conversion reached 25% when conditions from Table 1 were applied (Table 2, entry 1). Running the reaction at lower temperature was again beneficial (Table 2, entry 3). As stressed by Knochel, LiCl accelerates the magnesium-halogen exchange (higher k1);6b we observed in our case that i PrMgCl 3 LiCl significantly improved the conversion of 2m into 3m (compare Table 2, entries 1, 4, and 6).

 

Decreasing the amount of MPBOi Pr 1 (1.1 equiv vs 1.9 equiv) slows down the rate of the direct addition of i PrMgCl 3 LiCl onto 1. As a result, a better, albeit still low, conversion of the aryl iodide was achieved (compare Table 2, entries 2 vs 1 and 5 vs 4). More generally, decreasing the amount of MPBOi Pr 1 has a practical consequence: crude materials even cleaner than usual are obtained and can be directly engaged in further transformation (Scheme 4).30

 

Withthe rate constant k2 being directly correlated tothe structure of the trapping agent, we wondered whether our procedure for the preparation of functionalized arylboronic esters could be applied to the corresponding pinacol derivative 2-isopropoxy-4,4,5,5-tetramethyl[1,3,2]dioxaborolane (PinBOi Pr, 6).31 Indeed, pinacol esters are the best-known arylboronic esters for SuzukiMiyaura reactions.1 We chose o-iodo trifluoromethylbenzene 2i and o-iodo anisole 2m as representative substrates (Scheme 6 and Table 3). In the case of the aryl iodide bearing an electronwithdrawing substituent, an excellent 93% yield in the pinacol ester 7i was obtained (Table 3, entry 1). In the borderline case of substrate 2m, PinBOi Pr 6 gave better results than MPBOi Pr 1, whichever alkyl Grignard reagent was used (compare Table 3, entries 3 vs 2 and 5 vs 4). The extent of nucleophilic addition of the isopropylmagnesium species onto 6 is probably lessened by the increased steric hindrance around the boron atom compared to 1. Finally, as seen in Table 2, the effect of the borate ester stoichiometry proved significant (compare Table 3, entries 6 vs 5).

 

CONCLUSION
Combining the generation, at 0 C, of the aryl Grignard reagent by magnesium-iodine exchange with its in situ trapping by a cyclic borate ester proved to be a very simple, safe, and selective procedure for the preparation, in excellent yields and crude purity, of functionalized arylboronic esters from electrondeficient aryl iodides. Regarding arylboronic hexylene glycol esters, the present procedure is complementary to the Pdcatalyzed borylation of electron-rich aryl halides with 4,4,6-trimethyl-1,3,2-dioxaborinane (methyl pentanediol borane).

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4-Hydroxy-2-(trifluoromethyl)phenylboronic acid, pinacol ester Catalog No.:AA007IGI CAS No.:1029439-76-6 MDL No.:MFCD15143616 MF:C13H16BF3O3 MW:288.0705	Methyl 5-hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate Catalog No.:AA0096GE CAS No.:1029439-78-8 MDL No.:MFCD18730326 MF:C14H19BO5 MW:278.1087
2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Catalog No.:AA009041 CAS No.:1029439-83-5 MDL No.:MFCD16996286 MF:C12H15BF2O3 MW:256.0535	3,5-difluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenol Catalog No.:AA00H9T4 CAS No.:1029439-87-9 MDL No.:MFCD22414561 MF:C12H15BF2O3 MW:256.0535
[3-(2-phenylethoxy)phenyl]boronic acid Catalog No.:AA01AHKQ CAS No.:1029439-94-8 MDL No.:MFCD11540660 MF:C14H15BO3 MW:242.0781	pent-2-en-1-amine hydrochloride Catalog No.:AA01AUGO CAS No.:102944-79-6 MDL No.:MFCD28891421 MF:C5H12ClN MW:121.6085
3'-methyl-2',5',6',7'-tetrahydrospiro[cyclohexane-1,4'-pyrazolo[3,4-b]pyridine]-6'-one Catalog No.:AA00IUUM CAS No.:1029475-77-1 MDL No.:MFCD22573534 MF:C12H17N3O MW:219.2829	(2E)-4-(1,1-Dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)but-2-enoic acid Catalog No.:AA01ARHT CAS No.:10295-14-4 MDL No.:MFCD11518886 MF:C11H9NO5S MW:267.2579
4-Cyclopropyl-2-[[(2,3-difluorophenyl)methyl]thio]-1,6-dihydro-6-oxo5-pyrimidinecarbonitrile Catalog No.:AA01ENIJ CAS No.:1029521-30-9 MDL No.:MFCD30182342 MF:C15H11F2N3OS MW:319.3291	Pyridine, 3-azido- Catalog No.:AA01AAHS CAS No.:10296-29-4 MDL No.:MFCD13175173 MF:C5H4N4 MW:120.1121
3-Chloro-5-nitroisoquinoline Catalog No.:AA007Y99 CAS No.:10296-47-6 MDL No.:MFCD09999239 MF:C9H5ClN2O2 MW:208.6012	2,3-dihydroxypropane-1-sulfonic acid Catalog No.:AA007IB6 CAS No.:10296-76-1 MDL No.:MFCD29047427 MF:C3H8O5S MW:156.1576
4-[(Piperidine-1-sulfonyl)methyl]benzonitrile Catalog No.:AA00H9T8 CAS No.:1029603-11-9 MDL No.:MFCD11115642 MF:C13H16N2O2S MW:264.3433	Methyl 4-[(piperidine-1-sulfonyl)methyl]benzoate Catalog No.:AA01EH70 CAS No.:1029603-13-1 MDL No.:MFCD11844173 MF:C14H19NO4S MW:297.3700
Dalbavancin IMpurity - A40926-B0 Catalog No.:AA0094AG CAS No.:102961-72-8 MDL No.: MF:C88H101Cl3N10O28 MW:1853.1527	(Z)-3-(P-Toluenesulfonyloxy)but-2-enoic acid methyl ester Catalog No.:AA00IMG7 CAS No.:1029612-18-7 MDL No.:MFCD30749294 MF:C12H14O5S MW:270.3016
2,5-Difluorothiobenzamide Catalog No.:AA01BBWA CAS No.:1029623-72-0 MDL No.:MFCD09757552 MF:C7H5F2NS MW:173.1831	(R,S)-4-Fmoc-3-carboxymethyl-piperazin-2-one Catalog No.:AA00H9T9 CAS No.:1029630-75-8 MDL No.:MFCD06656482 MF:C21H20N2O5 MW:380.3939
2-[(5-Methylpyrazine-2-carbonyl)amino]propylamine hydrochloride Catalog No.:AA01F2DR CAS No.:1029634-15-8 MDL No.:MFCD04116911 MF:C9H15ClN4O MW:230.6946	3-Chloro-5-methoxyphenylisocyanide Catalog No.:AA01FDYK CAS No.:1029634-54-5 MDL No.:MFCD06798048 MF:C8H6ClNO MW:167.5923
3-(4-Fluorophenyl)pyrrolidine, HCl Catalog No.:AA008UWW CAS No.:1029636-03-0 MDL No.:MFCD03094755 MF:C10H13ClFN MW:201.6683	3-Difluoromethyl-5-(4-methoxyphenyl)pyrazole Catalog No.:AA00H9TA CAS No.:1029636-42-7 MDL No.:MFCD04039282 MF:C11H10F2N2O MW:224.2067
2-Chloro-4-(trifluoromethyl)phenylhydrazine, HCl Catalog No.:AA0035UN CAS No.:1029649-46-4 MDL No.:MFCD03094209 MF:C7H7Cl2F3N2 MW:247.0451	2-(4-fluorophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane Catalog No.:AA00H9TB CAS No.:1029653-69-7 MDL No.:MFCD08457859 MF:C12H16BFO2 MW:222.0636
2-Methoxy-5-methylpyridine-3-boronic acid Catalog No.:AA007Y98 CAS No.:1029654-27-0 MDL No.:MFCD07437974 MF:C7H10BNO3 MW:166.9702	2-Chloro-3-fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Catalog No.:AA00H9TI CAS No.:1029654-43-0 MDL No.:MFCD07787387 MF: MW:
2-Chloro-1-(tetrahydro-2h-pyran-2-yl)-1h-imidazole-5-boronic acid pinacol ester Catalog No.:AA008SK6 CAS No.:1029684-36-3 MDL No.:MFCD11100958 MF:C14H22BClN2O3 MW:312.6001	1-(Tetrahydro-2h-pyran-2-yl)-1h-imidazole-5-boronic acid pinacol ester Catalog No.:AA003D1R CAS No.:1029684-37-4 MDL No.:MFCD11100960 MF:C14H23BN2O3 MW:278.1550
(S)-5,6-DIFLUORO-INDAN-1-YLAMINE HYDROCHLORIDE Catalog No.:AA01DTEU CAS No.:1029689-74-4 MDL No.:MFCD22393185 MF:C9H10ClF2N MW:205.6322	(2-Methoxypyridin-4-yl)methanamine dihydrochloride Catalog No.:AA008UP9 CAS No.:1029689-75-5 MDL No.:MFCD20327972 MF:C7H12Cl2N2O MW:211.0890
Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate hydrochloride Catalog No.:AA008RMI CAS No.:1029689-82-4 MDL No.:MFCD08460905 MF:C11H14ClNO2 MW:227.6874	2-(3-Oxocyclopentyl)isoindoline-1,3-dione Catalog No.:AA0098ZD CAS No.:1029691-06-2 MDL No.:MFCD18910252 MF:C13H11NO3 MW:229.2313
2-(Difluoromethyl)-6-methylpyridine Catalog No.:AA00H9TK CAS No.:1029691-30-2 MDL No.:MFCD16140193 MF:C7H7F2N MW:143.1340	1-Chloro-4-iodobutane Catalog No.:AA003AYP CAS No.:10297-05-9 MDL No.:MFCD00039415 MF:C4H8ClI MW:218.4638
6-Chloro-1-hexyne Catalog No.:AA003N2E CAS No.:10297-06-0 MDL No.:MFCD00013697 MF:C6H9Cl MW:116.5887	Oct-7-ynoic acid Catalog No.:AA00863O CAS No.:10297-09-3 MDL No.:MFCD19228078 MF:C8H12O2 MW:140.1797
4-Methylsulphonylacetophenone Catalog No.:AA003K6I CAS No.:10297-73-1 MDL No.:MFCD00025072 MF:C9H10O3S MW:198.2389	(R)-Fmoc-2-amino-3-(3-tert-butoxycarbonyl-propylsulfanyl)-propionic acid Catalog No.:AA008WX4 CAS No.:102971-73-3 MDL No.:MFCD11226818 MF:C26H31NO6S MW:485.5924
Incb28060 Catalog No.:AA003A97 CAS No.:1029712-80-8 MDL No.:MFCD18633285 MF:C23H17FN6O MW:412.4191	4-Acetyl-2-fluorobenzoic acid Catalog No.:AA0091NC CAS No.:1029714-95-1 MDL No.:MFCD20660015 MF:C9H7FO3 MW:182.1485
(S)-2-(Pyrrolidin-3-yloxy)pyridine dihydrochloride Catalog No.:AA009291 CAS No.:1029715-21-6 MDL No.:MFCD01722200 MF:C9H14Cl2N2O MW:237.1263	[2-(Pyridin-2-yloxy)-ethyl]-carbamic acid tert-butyl ester Catalog No.:AA0093HR CAS No.:1029715-22-7 MDL No.:MFCD22565667 MF:C12H18N2O3 MW:238.2829
1-(Oxolan-3-yl)-1H-pyrazole-4-boronic acid pinacol ester Catalog No.:AA008XML CAS No.:1029715-63-6 MDL No.:MFCD18383269 MF:C13H21BN2O3 MW:264.1284	tert-Butyl n-[4-(hydroxymethyl)oxan-4-yl]carbamate Catalog No.:AA00H9TM CAS No.:1029716-09-3 MDL No.:MFCD18374720 MF:C11H21NO4 MW:231.2887
1-(1-Ethoxyethyl)-1H-pyrazole-4-boronic acid pinacol ester Catalog No.:AA003CPL CAS No.:1029716-44-6 MDL No.:MFCD11857753 MF:C13H23BN2O3 MW:266.1443	4-(dihydroxyboranyl)-2,3-difluorobenzoic acid Catalog No.:AA008SRV CAS No.:1029716-92-4 MDL No.:MFCD06203343 MF:C7H5BF2O4 MW:201.9200
3,5-Difluoro-4-carboxyphenylboronic acid Catalog No.:AA007Y93 CAS No.:1029716-94-6 MDL No.:MFCD13181636 MF:C7H5BF2O4 MW:201.9200	5-Chloro-3-(3-fluorobenzyl)-1,2,4-thiadiazole Catalog No.:AA00H9TN CAS No.:1029718-68-0 MDL No.:MFCD14707331 MF:C9H6ClFN2S MW:228.6737
5-Chloro-3-[(4-methoxyphenyl)methyl]-1,2,4-thiadiazole Catalog No.:AA00H9TO CAS No.:1029718-72-6 MDL No.:MFCD14707338 MF:C10H9ClN2OS MW:240.7093	2-(2-methoxyphenyl)ethanimidamide hydrochloride Catalog No.:AA00J1AJ CAS No.:1029718-90-8 MDL No.:MFCD11841268 MF:C9H13ClN2O MW:200.6653
tert-Butyl 3,3-difluorocyclobutylcarbamate Catalog No.:AA008XH0 CAS No.:1029720-19-1 MDL No.:MFCD10001483 MF:C9H15F2NO2 MW:207.2177	8-Bromo-3-chloro-isoquinoline Catalog No.:AA008TT2 CAS No.:1029720-63-5 MDL No.:MFCD11044698 MF:C9H5BrClN MW:242.4997
7-Bromo-3-chloroisoquinoline Catalog No.:AA00387A CAS No.:1029720-65-7 MDL No.:MFCD11044699 MF:C9H5BrClN MW:242.4997	5-Bromo-3-chloroisoquinoline Catalog No.:AA007Y92 CAS No.:1029720-67-9 MDL No.:MFCD11044700 MF:C9H5BrClN MW:242.4997
5-chloropyrido[4,3-d]pyrimidine Catalog No.:AA01C713 CAS No.:1029720-78-2 MDL No.:MFCD11044733 MF:C7H4ClN3 MW:165.5798	Ethyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate Catalog No.:AA008TM0 CAS No.:1029720-98-6 MDL No.:MFCD11044793 MF:C9H13N3O2 MW:195.2184
4-Oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid Catalog No.:AA008ZD1 CAS No.:1029721-02-5 MDL No.:MFCD11044795 MF:C7H7N3O3 MW:181.1488	2-bromo-1-(3-chloro-4-methoxyphenyl)propan-1-one Catalog No.:AA01BDUQ CAS No.:102976-53-4 MDL No.:MFCD11182391 MF:C10H10BrClO2 MW:277.5422
6-[4-(2-ethoxyphenyl)piperazin-1-yl]-2,3-dihydropyridazine-3-thione Catalog No.:AA01BE9M CAS No.:1029792-94-6 MDL No.:MFCD14729822 MF:C16H20N4OS MW:316.4212	4-Chloro-3-nitroanisole Catalog No.:AA003L2D CAS No.:10298-80-3 MDL No.:MFCD00007077 MF:C7H6ClNO3 MW:187.5804
4-Ethoxy-1-fluoro-2-nitrobenzene Catalog No.:AA00H9TR CAS No.:10298-81-4 MDL No.:MFCD17014026 MF:C8H8FNO3 MW:185.1524	Pyridine, 2-[(3S)-3-pyrrolidinyloxy]- Catalog No.:AA009290 CAS No.:1029805-88-6 MDL No.:MFCD15475015 MF:C9H12N2O MW:164.2044
4-(Methoxymethyl)oxan-4-amine Catalog No.:AA01ALQF CAS No.:1029805-91-1 MDL No.:MFCD22398294 MF:C7H15NO2 MW:145.1995	N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide Catalog No.:AA00357L CAS No.:1029872-54-5 MDL No.:MFCD18074504 MF:C46H35Cl2F4N6O6S2 MW:978.8363
Trelagliptin succinate Catalog No.:AA00H9TT CAS No.:1029877-94-8 MDL No.:MFCD22665720 MF:C22H26FN5O6 MW:475.4701	3-Fluoropyridine-4-boronic acid hydrate Catalog No.:AA003JF1 CAS No.:1029880-18-9 MDL No.:MFCD03788558 MF:C5H7BFNO3 MW:158.9234
2,5-Diacetoxyhexane Catalog No.:AA003FTP CAS No.:10299-35-1 MDL No.:MFCD09038521 MF:C10H18O4 MW:202.2475	8-AZAADENOSINE Catalog No.:AA00863F CAS No.:10299-44-2 MDL No.:MFCD01631207 MF:C9H12N6O4 MW:268.2294
5-Amino-1-(2,4-difluorophenyl)-1h-pyrazole-4-carbonitrile Catalog No.:AA00JV28 CAS No.:102996-25-8 MDL No.:MFCD03407393 MF:C10H6F2N4 MW:220.1782	4-methyl-2-nitro-5-(4-phenylpiperazin-1-yl)aniline hydrochloride Catalog No.:AA00IU2J CAS No.:1029987-67-4 MDL No.:MFCD04035636 MF:C17H20ClN4O2 MW:347.8193
(2Z)-3-{[4-(4-chlorophenyl)-1H-pyrazol-5-yl]amino}-2-(4-methylbenzenesulfonyl)prop-2-enenitrile Catalog No.:AA00IUYD CAS No.:1029989-13-6 MDL No.:MFCD03102626 MF:C19H15ClN4O2S MW:398.8660	N-({6-chloroimidazo[1,2-a]pyridin-3-yl}methyl)adamantan-1-amine hydrochloride Catalog No.:AA00IQQ8 CAS No.:1029989-47-6 MDL No.:MFCD08281888 MF:C18H23Cl2N3 MW:352.3013
2-(morpholin-4-yl)-5-(1H-pyrazol-5-yl)aniline Catalog No.:AA00IVVU CAS No.:1029989-48-7 MDL No.:MFCD08281898 MF:C13H16N4O MW:244.2923	2-{[(furan-2-yl)methyl]amino}-4-(4-methylphenyl)-4-oxobutanoic acid hydrochloride Catalog No.:AA00IZJQ CAS No.:1029989-66-9 MDL No.:MFCD16074863 MF:C16H18ClNO4 MW:323.7714
1-(Cyclohexylamino)propan-2-ol Catalog No.:AA009MTU CAS No.:103-00-4 MDL No.:MFCD00021322 MF:C9H19NO MW:157.2533	N-Phenylglycine Catalog No.:AA003T8H CAS No.:103-01-5 MDL No.:MFCD00014009 MF:C8H9NO2 MW:151.1626
2-Phenylhydrazinecarboxamide Catalog No.:AA003EK4 CAS No.:103-03-7 MDL No.:MFCD00007942 MF:C7H9N3O MW:151.1659	(Phenylthio)acetic acid Catalog No.:AA003BZ4 CAS No.:103-04-8 MDL No.:MFCD00004355 MF:C8H8O2S MW:168.2129
2-Methyl-4-phenyl-2-butanol Catalog No.:AA003HKK CAS No.:103-05-9 MDL No.:MFCD00004472 MF:C11H16O MW:164.2441	2-Ethylhexyl acrylate Catalog No.:AA003H51 CAS No.:103-11-7 MDL No.:MFCD00009495 MF:C11H20O2 MW:184.2753
Hydroquinone monobenzyl ether Catalog No.:AA003KQZ CAS No.:103-16-2 MDL No.:MFCD10687031 MF:C13H12O2 MW:200.2332	Chlorbensid Catalog No.:AA01DZB8 CAS No.:103-17-3 MDL No.:MFCD00055267 MF:C13H10Cl2S MW:269.1895
P-Tolyl disulfide Catalog No.:AA003TYL CAS No.:103-19-5 MDL No.:MFCD00008547 MF:C14H14S2 MW:246.3910	Bis(2-ethylhexyl) adipate Catalog No.:AA003O5S CAS No.:103-23-1 MDL No.:MFCD00009496 MF:C22H42O4 MW:370.5665
AZELAIC ACID DI(2-ETHYLHEXYL) ESTER Catalog No.:AA003NV2 CAS No.:103-24-2 MDL No.:MFCD00040496 MF:C25H48O4 MW:412.6462	Methyl 3-phenylpropionate Catalog No.:AA003JT2 CAS No.:103-25-3 MDL No.:MFCD00017209 MF:C10H12O2 MW:164.2011
Methyl cinnamate Catalog No.:AA00H9TU CAS No.:103-26-4 MDL No.:MFCD00008458 MF:C10H10O2 MW:162.1852	Bibenzyl Catalog No.:AA003DC4 CAS No.:103-29-7 MDL No.:MFCD00004796 MF:C14H14 MW:182.2610
Trans-stilbene Catalog No.:AA003UWJ CAS No.:103-30-0 MDL No.:MFCD00064300 MF:C14H12 MW:180.2451	4-Styrylpyridine Catalog No.:AA003LY3 CAS No.:103-31-1 MDL No.:MFCD00137749 MF:C13H11N MW:181.2331
N-Phenylbenzylamine Catalog No.:AA00359H CAS No.:103-32-2 MDL No.:MFCD00003018 MF:C13H13N MW:183.2490	Azobenzene Catalog No.:AA0038A5 CAS No.:103-33-3 MDL No.:MFCD00003022 MF:C12H10N2 MW:182.2212
4,4-Dithiodimorpholine Catalog No.:AA003KDQ CAS No.:103-34-4 MDL No.:MFCD00023319 MF:C8H16N2O2S2 MW:236.3548	Ethyl cinnamate Catalog No.:AA003QBS CAS No.:103-36-6 MDL No.:MFCD00009189 MF:C11H12O2 MW:176.2118
Benzyl butyrate Catalog No.:AA003O18 CAS No.:103-37-7 MDL No.:MFCD00027133 MF:C11H14O2 MW:178.2277	2-((1-Phenoxypropan-2-yl)amino)ethanol Catalog No.:AA003G4R CAS No.:103-39-9 MDL No.:MFCD00713871 MF:C11H17NO2 MW:195.2582
Succinic acid monobenzyl ester Catalog No.:AA003UDK CAS No.:103-40-2 MDL No.:MFCD00447717 MF:C11H12O4 MW:208.2106	Benzyl cinnamate Catalog No.:AA003O1A CAS No.:103-41-3 MDL No.:MFCD00004789 MF:C16H14O2 MW:238.2812
2-ETHYLHEXYL VINYL ETHER Catalog No.:AA003H57 CAS No.:103-44-6 MDL No.:MFCD00053800 MF:C10H20O MW:156.2652	Phenethyl acetate Catalog No.:AA003TL7 CAS No.:103-45-7 MDL No.:MFCD00008720 MF:C10H12O2 MW:164.2011
(Benzylthio)acetic acid Catalog No.:AA003BWT CAS No.:103-46-8 MDL No.:MFCD00004358 MF:C9H10O2S MW:182.2395	N-Cyclohexyltaurine Catalog No.:AA003SUI CAS No.:103-47-9 MDL No.:MFCD00003835 MF:C8H17NO3S MW:207.2905
Dibenzylamine Catalog No.:AA00H9TW CAS No.:103-49-1 MDL No.:MFCD00004770 MF:C14H15N MW:197.2756	Benzyl ether Catalog No.:AA003P92 CAS No.:103-50-4 MDL No.:MFCD00004780 MF:C14H14O MW:198.2604
Phenethyl cinnamate Catalog No.:AA003TL9 CAS No.:103-53-7 MDL No.:MFCD00022050 MF:C17H16O2 MW:252.3077	Cinnamyl acetate Catalog No.:AA00H9TX CAS No.:103-54-8 MDL No.:MFCD00008722 MF:C11H12O2 MW:176.2118
N1-Benzyl-N2,N2-dimethylethane-1,2-diamine Catalog No.:AA003SPB CAS No.:103-55-9 MDL No.:MFCD00008334 MF:C11H18N2 MW:178.2740	Cinnamyl propionate Catalog No.:AA003OU5 CAS No.:103-56-0 MDL No.:MFCD00048610 MF:C12H14O2 MW:190.2384
2-Phenoxyethyl isobutyrate Catalog No.:AA003TLS CAS No.:103-60-6 MDL No.:MFCD00027363 MF:C12H16O3 MW:208.2536	butanoic acid 3-phenyl-2-propenyl ester Catalog No.:AA003OIH CAS No.:103-61-7 MDL No.:MFCD00027135 MF:C13H16O2 MW:204.2649
(2-Bromoethyl)benzene Catalog No.:AA00H9TY CAS No.:103-63-9 MDL No.:MFCD00000240 MF:C8H9Br MW:185.0611	2-Bromovinylbenzene Catalog No.:AA003O37 CAS No.:103-64-0 MDL No.:MFCD00000185 MF:C8H7Br MW:183.0452
Propylbenzene Catalog No.:AA003TX9 CAS No.:103-65-1 MDL No.:MFCD00009377 MF:C9H12 MW:120.1916	N-Methylbenzylamine Catalog No.:AA00359K CAS No.:103-67-3 MDL No.:MFCD00008289 MF:C8H11N MW:121.1796
N-Ethylaniline Catalog No.:AA0035AX CAS No.:103-69-5 MDL No.:MFCD00009025 MF:C8H11N MW:121.1796	N-Phenylformamide Catalog No.:AA003QLX CAS No.:103-70-8 MDL No.:MFCD00003276 MF:C7H7NO MW:121.1366
Phenyl isocyanate Catalog No.:AA0085D6 CAS No.:103-71-9 MDL No.:MFCD00001994 MF:C7H5NO MW:119.1207	Isothiocyanatobenzene Catalog No.:AA003R2W CAS No.:103-72-0 MDL No.:MFCD00004798 MF:C7H5NS MW:135.1863
Phenetole Catalog No.:AA003TLE CAS No.:103-73-1 MDL No.:MFCD00009090 MF:C8H10O MW:122.1644	2-Pyridineethanol Catalog No.:AA0037YI CAS No.:103-74-2 MDL No.:MFCD00006364 MF:C7H9NO MW:123.1525
1-Piperazineethanol Catalog No.:AA00357H CAS No.:103-76-4 MDL No.:MFCD00005970 MF:C6H14N2O MW:130.1882	CYCLOHEXYLACETONE Catalog No.:AA003P2K CAS No.:103-78-6 MDL No.:MFCD00019396 MF:C9H16O MW:140.2227
Phenylacetyl chloride Catalog No.:AA0035E9 CAS No.:103-80-0 MDL No.:MFCD00000729 MF:C8H7ClO MW:154.5936	2-Phenylacetamide Catalog No.:AA00327C CAS No.:103-81-1 MDL No.:MFCD18449377 MF:C8H9NO MW:135.1632
N,N-Dimethylbenzylamine Catalog No.:AA003SI6 CAS No.:103-83-3 MDL No.:MFCD00008329 MF:C9H13N MW:135.2062	Acetanilide Catalog No.:AA0034CM CAS No.:103-84-4 MDL No.:MFCD00008674 MF:C8H9NO MW:135.1632
1-Phenylthiourea Catalog No.:AA003EK5 CAS No.:103-85-5 MDL No.:MFCD00004933 MF:C7H8N2S MW:152.2168	Phenol,4-(2-aminopropyl)- Catalog No.:AA00856U CAS No.:103-86-6 MDL No.:MFCD00599960 MF:C9H13NO MW:151.2056
4'-Bromoacetanilide Catalog No.:AA003KWJ CAS No.:103-88-8 MDL No.:MFCD00000092 MF:C8H8BrNO MW:214.0592	4'-Methylacetanilide Catalog No.:AA003410 CAS No.:103-89-9 MDL No.:MFCD00008677 MF:C9H11NO MW:149.1897
Acetaminophen Catalog No.:AA0033T3 CAS No.:103-90-2 MDL No.:MFCD00002328 MF:C8H9NO2 MW:151.1626	Acetic acid, [(4-aminophenyl)amino]oxo- Catalog No.:AA01CBND CAS No.:103-92-4 MDL No.:MFCD00007852 MF:C8H8N2O3 MW:180.1607
4-Nitrophenyloxamic acid Catalog No.:AA003LTL CAS No.:103-94-6 MDL No.:MFCD00014709 MF:C8H6N2O5 MW:210.1436	N,N'-BIS(1-METHYLHEPTYL)-P-PHENYLENEDIAMINE Catalog No.:AA008R44 CAS No.:103-96-8 MDL No.:MFCD00027305 MF:C22H40N2 MW:332.5664
N-(4-hydroxyphenyl)dodecanamide Catalog No.:AA009QRX CAS No.:103-98-0 MDL No.:MFCD00020147 MF:C18H29NO2 MW:291.4284	4-(Dimethylamino)chalcone Catalog No.:AA007Y8B CAS No.:1030-27-9 MDL No.:MFCD00168677 MF:C17H17NO MW:251.3230
Methyl 2-phenylimidazo[1,2-a]pyridine-7-carboxylate Catalog No.:AA0095N8 CAS No.:1030-33-7 MDL No.:MFCD00022628 MF:C15H12N2O2 MW:252.2680	3'-O-Methyladenosine Catalog No.:AA007Y8M CAS No.:10300-22-8 MDL No.:MFCD00057003 MF:C11H15N5O4 MW:281.2679
3'-O-Methylguanosine Catalog No.:AA008SLE CAS No.:10300-27-3 MDL No.:MFCD00057057 MF:C11H15N5O5 MW:297.2673	Chloroacetamidine HCl Catalog No.:AA003OQ9 CAS No.:10300-69-3 MDL No.:MFCD00053013 MF:C2H6Cl2N2 MW:128.9884
Methyl2-acetamido-4,6-O-benzylidene-2-deoxy-b-D-glucopyranoside Catalog No.:AA008X0W CAS No.:10300-76-2 MDL No.:MFCD04039590 MF:C16H21NO6 MW:323.3410	ethyl 5-(aminomethyl)-2-furoate hydrochloride Catalog No.:AA00J3D8 CAS No.:1030012-30-6 MDL No.:MFCD02815367 MF:C8H12ClNO3 MW:205.6388
4-[5-(Aminomethyl)thien-2-yl]-2-methyl-1,3-thiazole diHCl Catalog No.:AA00H9TZ CAS No.:1030012-47-5 MDL No.:MFCD07704030 MF:C9H12Cl2N2S2 MW:283.2410	Ethyl 2-cyclopropyl-4-methyl-1,3-oxazole-5-carboxylate Catalog No.:AA01A5L6 CAS No.:1030014-04-0 MDL No.:MFCD21291600 MF:C10H13NO3 MW:195.2151
Ethyl 1-(4-chlorobenzyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate Catalog No.:AA0090WM CAS No.:1030014-82-4 MDL No.:MFCD10758099 MF:C13H14ClN3O2 MW:279.7222	Ethyl 5-methyl-1-(4-methylbenzyl)-1H-1,2,3-triazole-4-carboxylate Catalog No.:AA0090WR CAS No.:1030014-84-6 MDL No.:MFCD10758096 MF:C14H17N3O2 MW:259.3037
5-nitro-1H-pyrazol-3-amine hydrochloride Catalog No.:AA01BTX2 CAS No.:1030018-90-6 MDL No.:MFCD28142358 MF:C3H5ClN4O2 MW:164.5504	CMP5 Catalog No.:AA01EQCW CAS No.:1030021-40-9 MDL No.: MF:C21H22ClN3 MW:351.8725
1-Methyl-3-((methylamino)methyl)quinolin-2(1H)-one hydrochloride Catalog No.:AA01FM97 CAS No.:1030022-56-0 MDL No.:MFCD09792407 MF:C12H15ClN2O MW:238.7133	2-Hydroxymethylmorpholine Catalog No.:AA007Y8L CAS No.:103003-01-6 MDL No.:MFCD03426271 MF:C5H11NO2 MW:117.1463
2-(Trifluoromethoxy)benzenesulfonyl chloride Catalog No.:AA003F2J CAS No.:103008-51-1 MDL No.:MFCD00052316 MF:C7H4ClF3O3S MW:260.6181	2-(dimethylsulfamoyl)benzene-1-sulfonyl chloride Catalog No.:AA01AFXQ CAS No.:103008-52-2 MDL No.:MFCD09811998 MF:C8H10ClNO4S2 MW:283.7523
ethyl 2-(chlorosulfonyl)benzoate Catalog No.:AA009KG8 CAS No.:103008-54-4 MDL No.:MFCD01961366 MF:C9H9ClO4S MW:248.6834	4-(5-amino-1,3,4-oxadiazol-2-yl)-1-phenylpyrrolidin-2-one Catalog No.:AA00J9CJ CAS No.:1030103-68-4 MDL No.:MFCD15119564 MF:C12H12N4O2 MW:244.2493
3-(1,3-Dioxolan-2-yl)thiophene-2-sulfonyl chloride Catalog No.:AA007Y8G CAS No.:103011-38-7 MDL No.:MFCD08271969 MF:C7H7ClO4S2 MW:254.7111	3-(1,3-dioxolan-2-yl)thiophene-2-sulfonamide Catalog No.:AA01E809 CAS No.:103011-39-8 MDL No.:MFCD30750670 MF:C7H9NO4S2 MW:235.2807
2-Propenoic acid, 2-cyano-3-(3-pyridinyl)-, ethyl ester, (2E)- Catalog No.:AA007I8M CAS No.:103011-95-6 MDL No.:MFCD00564622 MF:C11H10N2O2 MW:202.2093	(E)-Ethyl2-cyano-5-methylhex-2-enoate Catalog No.:AA01DZB9 CAS No.:103011-96-7 MDL No.: MF:C18H14D4FNO2S MW:335.4291
3-Phenyl-9h-carbazole Catalog No.:AA0091XR CAS No.:103012-26-6 MDL No.:MFCD22052094 MF:C18H13N MW:243.3025	7-(2-methylphenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one Catalog No.:AA00J0MD CAS No.:1030120-83-2 MDL No.:MFCD16639688 MF:C13H10N2OS MW:242.2963
6-fluoro-1-methyl-4-oxo-7-(piperidin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid Catalog No.:AA00J0HW CAS No.:1030120-88-7 MDL No.:MFCD14729054 MF:C16H17FN2O3 MW:304.3162	1-(2H-1,3-benzodioxol-5-yl)-N-[5-(4-fluorophenyl)-1H,4H-thieno[2,3-d]pyrimidin-4-ylidene]methanamine Catalog No.:AA01C13I CAS No.:1030123-90-0 MDL No.:MFCD15017488 MF:C20H14FN3O2S MW:379.4075
tert-Butyl 4-(prop-2-yn-1-ylcarbamoyl)piperidine-1-carboxylate Catalog No.:AA01B909 CAS No.:1030181-52-2 MDL No.:MFCD10605357 MF:C14H22N2O3 MW:266.3361	6-Chloro-N-(4-methylphenyl)-2-pyrazinamine Catalog No.:AA01FOCP CAS No.:1030187-29-1 MDL No.: MF:C11H10ClN3 MW:219.6702
4-Amino-1-(2,3,5-tri-o-acetyl-beta-d-ribofuranosyl)-1,3,5-triazin-2(1h)-one Catalog No.:AA007I8E CAS No.:10302-78-0 MDL No.:MFCD11113159 MF:C14H18N4O8 MW:370.3147	3',5'-di-o-toluoyl-2-deoxy-5-azacytosine Catalog No.:AA008X4R CAS No.:10302-79-1 MDL No.:MFCD09750854 MF:C24H24N4O6 MW:464.4706
1.2-dibromoethane-1-sulfonyl fluoride Catalog No.:AA01EIVS CAS No.:103020-97-9 MDL No.:MFCD31615713 MF:C2H3Br2FO2S MW:269.9154	Ethenesulfonyl fluoride, 1-bromo- Catalog No.:AA007Y8E CAS No.:103020-98-0 MDL No.:MFCD29054906 MF:C2H2BrFO2S MW:189.0035
HS38 Catalog No.:AA01DZBA CAS No.:1030203-81-6 MDL No.:MFCD10610687 MF:C14H12ClN5O2S MW:349.7954	trans-4-(Dimethylamino)cyclohexanol Catalog No.:AA008SR1 CAS No.:103023-51-4 MDL No.:MFCD09258736 MF:C8H17NO MW:143.2267
1,4-Dioxa-9-thia-12-azadispiro[4.2.4.2]tetradecane-11-carboxylic acid Catalog No.:AA0090V1 CAS No.:1030253-98-5 MDL No.:MFCD06411612 MF:C11H17NO4S MW:259.3220	4-Acetyl-8-benzyl-1-thia-4,8-diazaspiro[4,5]decane-3-carboxylic acid, HCl Catalog No.:AA0090W4 CAS No.:1030253-99-6 MDL No.:MFCD06795478 MF:C17H23ClN2O3S MW:370.8941
2-Amino-1-(furan-2-ylmethyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile Catalog No.:AA008631 CAS No.:103026-02-4 MDL No.:MFCD06655398 MF:C12H13N3O MW:215.2511	2-Amino-1-cyclopentyl-4,5-dimethyl-1h-pyrrole-3-carbonitrile Catalog No.:AA01C4ZB CAS No.:103026-11-5 MDL No.:MFCD08898941 MF:C12H17N3 MW:203.2835
7-(furan-2-ylmethyl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine Catalog No.:AA007I8G CAS No.:103026-12-6 MDL No.:MFCD06655548 MF:C13H14N4O MW:242.2765	4-Chloro-7-(2-furylmethyl)-5,6-dimethyl-7h-pyrrolo[2,3-d]pyrimidine Catalog No.:AA007Y8C CAS No.:103026-14-8 MDL No.:MFCD09040565 MF:C13H12ClN3O MW:261.7069
7-cyclohexyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol Catalog No.:AA01BA8T CAS No.:103026-47-7 MDL No.:MFCD28397592 MF:C14H19N3O MW:245.3202	7-cyclopentyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-ol Catalog No.:AA01C59S CAS No.:103026-49-9 MDL No.:MFCD29907070 MF:C13H17N3O MW:231.2936
Dehydro Nisoldipine Catalog No.:AA008630 CAS No.:103026-83-1 MDL No.:MFCD10565997 MF:C20H22N2O6 MW:386.3985	3-Succinamidophenylboronic acid, pinacol ester Catalog No.:AA003LVA CAS No.:1030269-28-3 MDL No.:MFCD06795662 MF:C16H22BNO5 MW:319.1606
3,5-BIS(PERFLUOROPROPYL)PYRAZOLE Catalog No.:AA009LIE CAS No.:1030269-34-1 MDL No.:MFCD06246012 MF:C9H2F14N2 MW:404.1032	6-chloronaphthalene-2-sulfonamide Catalog No.:AA01EIX9 CAS No.:103027-67-4 MDL No.:MFCD27941009 MF:C10H8ClNO2S MW:241.6940
1H-Indole-2,6-dicarboxylic acid Catalog No.:AA008RNG CAS No.:103027-97-0 MDL No.:MFCD03095180 MF:C10H7NO4 MW:205.1669	4-Bromo-8-methoxyquinoline Catalog No.:AA003KWI CAS No.:103028-31-5 MDL No.:MFCD08063209 MF:C10H8BrNO MW:238.0806
6-Bromo-8-methoxyquinoline Catalog No.:AA0095S8 CAS No.:103028-32-6 MDL No.:MFCD11878494 MF:C10H8BrNO MW:238.0806	1-(4-methylpyridin-2-yl)butan-1-one Catalog No.:AA01C023 CAS No.:103028-75-7 MDL No.:MFCD18897781 MF:C10H13NO MW:163.2163
6-Methoxy-2,3-dihydro-1H-inden-1-amine Catalog No.:AA007I8A CAS No.:103028-81-5 MDL No.:MFCD04972430 MF:C10H13NO MW:163.2163	1-Amino-1,2,3,4-tetrahydronaphthalen-2-ol hydrochloride Catalog No.:AA00H9U5 CAS No.:103028-83-7 MDL No.:MFCD07792554 MF:C10H14ClNO MW:199.6773
3-Amino-1,2,3,4-tetrahydronaphthalen-2-ol hydrochloride Catalog No.:AA01FM9Z CAS No.:103028-84-8 MDL No.:MFCD28388520 MF:C10H14ClNO MW:199.6773	5-(Anilinocarbonothioyl)-4,5,6,7-tetrahydro-3h-imidazo[4,5-c]pyridine-6-carboxylic acid hydrochloride Catalog No.:AA01AQWA CAS No.:1030285-50-7 MDL No.:MFCD04448843 MF:C14H15ClN4O2S MW:338.8125
(4-(2,5-Dioxoimidazolidin-4-yl)phenyl)boronic acid Catalog No.:AA01FLY8 CAS No.:1030287-04-7 MDL No.:MFCD03541055 MF:C9H9BN2O4 MW:219.9898	2-Hydrazinylbenzonitrile hydrochloride Catalog No.:AA003A8D CAS No.:1030287-80-9 MDL No.:MFCD03094641 MF:C7H8ClN3 MW:169.6115
1-(4-methoxybenzoyl)piperazine hydrochloride Catalog No.:AA019L6N CAS No.:1030288-85-7 MDL No.:MFCD09863359 MF:C12H17ClN2O2 MW:256.7286	5-(2-chlorophenyl)imidazolidine-2,4-dione Catalog No.:AA01DX4L CAS No.:103029-09-0 MDL No.:MFCD17237684 MF:C9H7ClN2O2 MW:210.6171
3-((2-(Pyridin-4-yl)ethyl)thio)propanoic acid Catalog No.:AA01CB1U CAS No.:103029-28-3 MDL No.:MFCD06795662 MF:C10H13NO2S MW:211.2807	2-Cyano-3-(pyridin-3-yl)acrylic acid Catalog No.:AA007I88 CAS No.:103029-74-9 MDL No.:MFCD02668152 MF:C9H6N2O2 MW:174.1561
3-Nitroquinolin-2-ol Catalog No.:AA007I87 CAS No.:103029-75-0 MDL No.:MFCD09754181 MF:C9H6N2O3 MW:190.1555	2-(2-hydroxy-4-methoxyphenyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid Catalog No.:AA00IT42 CAS No.:1030291-57-6 MDL No.:MFCD00955337 MF:C13H17NO4S MW:283.3434
(S)-Methyl 2,3-dihydroxypropanoate Catalog No.:AA007I82 CAS No.:10303-88-5 MDL No.:MFCD14636488 MF:C4H8O4 MW:120.1039	Adamantane-1,3-diamine Catalog No.:AA00862Q CAS No.:10303-95-4 MDL No.:MFCD01831403 MF:C10H18N2 MW:166.2633