Home Sulfonamines 1219633-99-4
1219633-99-4,MFCD20527887
Catalog No.:AA01ENKP

1219633-99-4 | N-[(3R,4S)-3-[4-(5-cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]-2-propanesulfonamide

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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01ENKP
Chemical Name:
N-[(3R,4S)-3-[4-(5-cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]-2-propanesulfonamide
CAS Number:
1219633-99-4
Molecular Formula:
C19H22N2O3S2
Molecular Weight:
390.5196
MDL Number:
MFCD20527887
SMILES:
CC(S(=O)(=O)N[C@H]1CCOC[C@@H]1c1ccc(cc1)c1ccc(s1)C#N)C
Properties
Computed Properties
 
Complexity:
614  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
3.3  

Literature

Title: An evaluation of using rat-derived single-dose neuropharmacokinetic parameters to project accurately large animal unbound brain drug concentrations.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121101

Title: Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction.

Journal: Behavioural brain research 20100901

Title: Roberts BM, et al. Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction. Behav Brain Res. 2010 Sep 1;212(1):41-8.

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Tags:1219633-99-4 Molecular Formula|1219633-99-4 MDL|1219633-99-4 SMILES|1219633-99-4 N-[(3R,4S)-3-[4-(5-cyano-2-thienyl)phenyl]tetrahydro-2H-pyran-4-yl]-2-propanesulfonamide