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19309-14-9,MFCD00238554
Catalog No.:AA00AOO8

19309-14-9 | Cardamonin

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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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1g
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AOO8
Chemical Name:
Cardamonin
CAS Number:
19309-14-9
Molecular Formula:
C16H14O4
Molecular Weight:
270.2800
MDL Number:
MFCD00238554
SMILES:
COc1cc(O)cc(c1C(=O)/C=C/c1ccccc1)O
Properties
Computed Properties
 
Complexity:
346  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
3.5  

Literature

Title: Effect of cardamonin on hepatic ischemia reperfusion induced in rats: Role of nitric oxide.

Journal: European journal of pharmacology 20171115

Title: Phytochemical and antimicrobial investigations of stilbenoids and flavonoids isolated from three species of Combretaceae.

Journal: Fitoterapia 20120701

Title: Cardamonin protects septic mice from acute lung injury by preventing endothelial barrier dysfunction.

Journal: Journal of biochemical and molecular toxicology 20120701

Title: Alpinia katsumadai H(AYATA) seed extract inhibit LPS-induced inflammation by induction of heme oxygenase-1 in RAW264.7 cells.

Journal: Inflammation 20120401

Title: Cardamonin exerts potent activity against multiple myeloma through blockade of NF-κB pathway in vitro.

Journal: Leukemia research 20120401

Title: Cardamonin from Alpinia rafflesiana inhibits inflammatory responses in IFN-γ/LPS-stimulated BV2 microglia via NF-κB signalling pathway.

Journal: International immunopharmacology 20120401

Title: Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.

Journal: British journal of pharmacology 20120201

Title: Analysis of cardamonin by square wave voltammetry.

Journal: Phytochemical analysis : PCA 20120101

Title: Cardamonin suppresses nitric oxide production via blocking the IFN-γ/STAT pathway in endotoxin-challenged peritoneal macrophages of ICR mice.

Journal: Life sciences 20110829

Title: Cardamonin stimulates glucose uptake through translocation of glucose transporter-4 in L6 myotubes.

Journal: Phytotherapy research : PTR 20110801

Title: Microbial glycosylation of cardamonin by Mucor spinosus.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110601

Title: N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.

Journal: Bioorganic & medicinal chemistry letters 20101201

Title: Antiproliferation of cardamonin is involved in mTOR on aortic smooth muscle cells in high fructose-induced insulin resistance rats.

Journal: European journal of pharmacology 20100901

Title: [Antiproliferation of cardamonin associated with mRNA expression of mTOR, Raptor and Rictor].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901

Title: Cardamonin is a bifunctional vasodilator that inhibits Ca(v)1.2 current and stimulates K(Ca)1.1 current in rat tail artery myocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20100201

Title: Cardamonin suppresses melanogenesis by inhibition of Wnt/beta-catenin signaling.

Journal: Biochemical and biophysical research communications 20091218

Title: Characterization of cardamonin metabolism by P450 in different species via HPLC-ESI-ion trap and UPLC-ESI-quadrupole mass spectrometry.

Journal: Acta pharmacologica Sinica 20091001

Title: Death receptor 5 promoter-enhancing compounds isolated from Catimbium speciosum and their enhancement effect on TRAIL-induced apoptosis.

Journal: Bioorganic & medicinal chemistry 20090915

Title: [Chemical study on petroleum ether portion of Sarcandra hainanensis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401

Title: [Studies on chemical constituents of alpinia katsumadai].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080601

Title: Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080401

Title: Bioactive secondary metabolites from Boesenbergia pandurata of Myanmar and their preferential cytotoxicity against human pancreatic cancer PANC-1 cell line in nutrient-deprived medium.

Journal: Journal of natural products 20071001

Title: Separation and determination of alpinetin and cardamonin by reverse micelle electrokinetic capillary chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20070312

Title: Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells.

Journal: Molecular immunology 20070201

Title: Comparison of the characterization on binding of alpinetin and cardamonin to lysozyme by spectroscopic methods.

Journal: International journal of biological macromolecules 20061115

Title: An unusual homoisoflavanone and a structurally-related dihydrochalcone from Polygonum ferrugineum (Polygonaceae).

Journal: Phytochemistry 20061001

Title: The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages.

Journal: British journal of pharmacology 20060901

Title: Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease.

Journal: Bioorganic & medicinal chemistry letters 20060615

Title: Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood.

Journal: European journal of pharmacology 20060524

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Anti-HIV-1 protease activity of compounds from Boesenbergia pandurata.

Journal: Bioorganic & medicinal chemistry 20060315

Title: Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera.

Journal: The Journal of pharmacology and experimental therapeutics 20060101

Title: Specific interaction of chalcone-protein: cardamonin binding site II on the human serum albumin molecule.

Journal: Biopolymers 20050901

Title: Determination of cardamonin using a chemiluminescent flow-injection method.

Journal: Phytochemical analysis : PCA 20050101

Title: Vasorelaxant effects of cardamonin and alpinetin from Alpinia henryi K. Schum.

Journal: Journal of cardiovascular pharmacology 20010501

Title: Wang S, et al. Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. Molecules. 2016 Aug 29;21(9). pii: E1145.

Title: Park MK, et al. Novel anti-nociceptive effects of cardamonin via blocking expression of cyclooxygenase-2 andtransglutaminase-2. Pharmacol Biochem Behav. 2014 Mar;118:10-5.

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