Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: Janus kinase 3 is expressed in erythrocytes, phosphorylated upon energy depletion and involved in the regulation of suicidal erythrocyte death.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Title: Differential regulation of proliferation and differentiation in neural precursor cells by the Jak pathway.
Journal: Stem cells (Dayton, Ohio) 20101001
Title: A novel indole-3-propanamide exerts its immunosuppressive activity by inhibiting JAK3 in T cells.
Journal: The Journal of pharmacology and experimental therapeutics 20091101
Title: The specificity of JAK3 kinase inhibitors.
Journal: Blood 20080215
Title: Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
Journal: Oncogene 20070816
Title: Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma.
Journal: Leukemia 20061001
Title: Interplay between epidermal growth factor receptor and Janus kinase 3 regulates polychlorinated biphenyl-induced matrix metalloproteinase-3 expression and transendothelial migration of tumor cells.
Journal: Molecular cancer research : MCR 20060601
Title: The JAK3 inhibitor WHI-P154 prevents PDGF-evoked process outgrowth in human neural precursor cells.
Journal: Journal of neurochemistry 20060401
Title: JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages.
Journal: Mediators of inflammation 20060101
Title: Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3.
Journal: Laboratory investigation; a journal of technical methods and pathology 20051201
Title: Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner.
Journal: British journal of pharmacology 20050701
Title: IL-4-dependent CD86 expression requires JAK/STAT6 activation and is negatively regulated by PKCdelta.
Journal: Cellular signalling 20040201
Title: Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.
Journal: Science (New York, N.Y.) 20031031
Title: Suppression of early T-cell-receptor-triggered cellular activation by the Janus kinase 3 inhibitor WHI-P-154.
Journal: Transplantation 20030615
Title: Augmentation of mast cell bactericidal activity by the anti-leukemic drug, 4-(3'bromo-4'-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline.
Journal: Leukemia & lymphoma 20020601
Title: Regulation of IGF-I mRNA and signal transducers and activators of transcription-3 and -5 (Stat-3 and -5) by GH in C2C12 myoblasts.
Journal: Endocrinology 20020201
Title: 4-[3-Bromo-4-hydroxyphenyl)amino]-6,7-dimethoxyquinazolin-1-ium chloride methanol solvate and 4-[(3-hydroxyphenyl)amino]-6,7-dimethoxy-1-quinazolinium chloride.
Journal: Acta crystallographica. Section C, Crystal structure communications 20010101
Title: Tyrosine kinase inhibitors against EGF receptor-positive malignancies.
Journal: Methods in molecular biology (Clifton, N.J.) 20010101
Title: Changelian PS, et al. The specificity of JAK3 kinase inhibitors. Blood. 2008 Feb 15;111(4):2155-7. Epub 2007 Dec 19.
Title: Zhang H, et al. WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells. Cancer Sci. 2014 Aug;105(8):1071-8.
