Home Oxazoles 22876-15-9
22876-15-9,MFCD02090048
Catalog No.:AA007P7D

22876-15-9 | 5-Methyl-3H-1,3-benzoxazol-2-one

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1g
95%
in stock  
$81.00   $57.00
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5g
98%
in stock  
$261.00   $183.00
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10g
98%
in stock  
$427.00   $299.00
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25g
98%
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$809.00   $567.00
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100g
98%
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$2,007.00   $1,405.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007P7D
Chemical Name:
5-Methyl-3H-1,3-benzoxazol-2-one
CAS Number:
22876-15-9
Molecular Formula:
C8H7NO2
Molecular Weight:
149.1467
MDL Number:
MFCD02090048
SMILES:
Cc1ccc2c(c1)[nH]c(=O)o2
NSC Number:
280710
Properties
Computed Properties
 
Complexity:
181  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
XLogP3:
1.5  

Downstream Synthesis Route

[1]SyntheticCommunications,1990,vol.20,p.693-701

[1]SyntheticCommunications,1990,vol.20,p.693-701

[1]GazzettaChimicaItaliana,1993,vol.123,p.683-686

[1]GazzettaChimicaItaliana,1993,vol.123,p.683-686

[1]Liacha,Messaoud;Yous,Saïd;Depreux,Patrick;Poupaert,JacquesH.;Lesieur,Daniel[Heterocycles,1999,vol.51,#8,p.1929-1943]

[2]Locationinpatent:schemeortableAidaR.Nadji-Boukrouche;Khoumeri,Omar;Terme,Thierry;Liacha,Messaoud;Vanellec,Patrice[ARKIVOC,2010,vol.2010,#10,p.358-370]

[3]Nadji-Boukrouche,AdaR.;Khoumeri,Omar;Terme,Thierry;Liacha,Messaoud;Vanelle,Patrice[Molecules,2015,vol.20,#1,p.1262-1276]

Literature

Title: Synthesis and biological activities of some 1,3-benzoxazol-2(3H)-one derivatives as anti-quorum sensing agents.

Journal: Arzneimittel-Forschung 20120701

Title: Synthesis and evaluation of analgesic, anti-inflammatory and antioxidant activities of new 6-acyl-3-alkyl-5-methyl-2(3H)-benzoxazolones.

Journal: Arzneimittel-Forschung 20080101

Title: 1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities.

Journal: Bioorganic & medicinal chemistry 20070901

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