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Title: Celecoxib and 2,5-dimethyl-celecoxib prevent cardiac remodeling inhibiting Akt-mediated signal transduction in an inherited dilated cardiomyopathy mouse model.
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Title: Enhancement of photodynamic therapy by 2,5-dimethyl celecoxib, a non-cyclooxygenase-2 inhibitor analog of celecoxib.
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Title: Dimethylcelecoxib inhibits mPGES-1 promoter activity by influencing EGR1 and NF-κB.
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Title: Antiangiogenic activities of 2,5-dimethyl-celecoxib on the tumor vasculature.
Journal: Molecular cancer therapeutics 20100301
Title: Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress.
Journal: Cancer letters 20090908
Title: Dimethylcelecoxib inhibits prostaglandin E2 production.
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Title: Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs.
Journal: Expert opinion on investigational drugs 20080201
Title: Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib.
Journal: Cancer research 20080201
Title: COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro.
Journal: Molecular cancer 20080101
Title: CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
Journal: Molecular pharmacology 20071101
Title: Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib.
Journal: Molecular cancer therapeutics 20070401
Title: Antitumor properties of dimethyl-celecoxib, a derivative of celecoxib that does not inhibit cyclooxygenase-2: implications for glioma therapy.
Journal: Neurosurgical focus 20060415
Title: Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo.
Journal: Molecular cancer 20060101
Title: Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib.
Journal: Blood 20051215
Title: Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo.
Journal: Cancer biology & therapy 20050501
Title: DMC: novel celecoxib derivatives to rap cancer.
Journal: Cancer biology & therapy 20050501
Title: Growth inhibitory effects of celecoxib in human umbilical vein endothelial cells are mediated through G1 arrest via multiple signaling mechanisms.
Journal: Molecular cancer therapeutics 20041201