Title: Oroxylin A prevents alcohol-induced hepatic steatosis through inhibition of hypoxia inducible factor 1alpha.
Journal: Chemico-biological interactions 20180401
Title: Induction of endothelium-dependent constriction of mesenteric arteries in endotoxemic hypotensive shock.
Journal: British journal of pharmacology 20160401
Title: Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest.
Journal: Toxicology letters 20130523
Title: Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20121101
Title: Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling.
Journal: Cellular signalling 20120801
Title: [Vasodilator effect of oroxylin A on thoracic aorta isolated from rats].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120801
Title: Activation of the unfolded protein response contributed to the selective cytotoxicity of oroxylin A in human hepatocellular carcinoma HepG2 cells.
Journal: Toxicology letters 20120720
Title: The role of Nrf2 and apoptotic signaling pathways in oroxylin A-mediated responses in HCT-116 colorectal adenocarcinoma cells and xenograft tumors.
Journal: Anti-cancer drugs 20120701
Title: Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts.
Journal: Pancreas 20120501
Title: Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production.
Journal: Bioorganic & medicinal chemistry letters 20120401
Title: Oroxylin A inhibits matrix metalloproteinase-2/9 expression and activation by up-regulating tissue inhibitor of metalloproteinase-2 and suppressing the ERK1/2 signaling pathway.
Journal: Toxicology letters 20120325
Title: Oroxylin A reverses CAM-DR of HepG2 cells by suppressing Integrinβ1 and its related pathway.
Journal: Toxicology and applied pharmacology 20120315
Title: Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae.
Journal: The AAPS journal 20120301
Title: Oroxylin A reverses multi-drug resistance of human hepatoma BEL7402/5-FU cells via downregulation of P-glycoprotein expression by inhibiting NF-κB signaling pathway.
Journal: Molecular carcinogenesis 20120201
Title: Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives.
Journal: Bioorganic & medicinal chemistry letters 20120115
Title: 4'-bromo-5,6,7-trimethoxyflavone represses lipopolysaccharide-induced iNOS and COX-2 expressions by suppressing the NF-κB signaling pathway in RAW 264.7 macrophages.
Journal: Bioorganic & medicinal chemistry letters 20120101
Title: STAT1 mediates oroxylin a inhibition of iNOS and pro-inflammatory cytokines expression in microglial BV-2 cells.
Journal: PloS one 20120101
Title: Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product.
Journal: Journal of pharmaceutical and biomedical analysis 20110325
Title: Oroxylin A increases BDNF production by activation of MAPK-CREB pathway in rat primary cortical neuronal culture.
Journal: Neuroscience research 20110301
Title: Oroxylin A, a flavonoid, stimulates adult neurogenesis in the hippocampal dentate gyrus region of mice.
Journal: Neurochemical research 20101101
Title: Synthesis and biological evaluation of novel benzyl-substituted flavones as free radical (DPPH) scavengers and α-glucosidase inhibitors.
Journal: Journal of Asian natural products research 20101101
Title: Flavonoids with prolyl oligopeptidase inhibitory activity isolated from Scutellaria racemosa Pers.
Journal: Fitoterapia 20100901
Title: Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes.
Journal: Pharmaceutical research 20100801
Title: Anti-pruritic effect of baicalin and its metabolites, baicalein and oroxylin A, in mice.
Journal: Acta pharmacologica Sinica 20100601
Title: Synergistic effect of 5-fluorouracil and the flavanoid oroxylin A on HepG2 human hepatocellular carcinoma and on H22 transplanted mice.
Journal: Cancer chemotherapy and pharmacology 20100201
Title: Involvement of p53 in oroxylin A-induced apoptosis in cancer cells.
Journal: Molecular carcinogenesis 20091201
Title: MAC-related mitochondrial pathway in oroxylin-A-induced apoptosis in human hepatocellular carcinoma HepG2 cells.
Journal: Cancer letters 20091101
Title: [Flavonoids from Scutellaria baicalensis and their bioactivities].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20091018
Title: Evaluation of the flavonoid oroxylin A as an inhibitor of P-glycoprotein-mediated cellular efflux.
Journal: Journal of natural products 20090901
Title: Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora.
Journal: Journal of natural products 20090601
Title: Apoptosis induction of oroxylin A in human cervical cancer HeLa cell line in vitro and in vivo.
Journal: Toxicology 20090304
Title: Oroxylin A suppresses invasion through down-regulating the expression of matrix metalloproteinase-2/9 in MDA-MB-435 human breast cancer cells.
Journal: European journal of pharmacology 20090128
Title: In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root.
Journal: Journal of biomedical science 20090101
Title: Oroxylin A induces G2/M phase cell-cycle arrest via inhibiting Cdk7-mediated expression of Cdc2/p34 in human gastric carcinoma BGC-823 cells.
Journal: The Journal of pharmacy and pharmacology 20081101
Title: The effects of acute and repeated oroxylin A treatments on Abeta(25-35)-induced memory impairment in mice.
Journal: Neuropharmacology 20081001
Title: Impacts of baicalein analogs with modification of the 6th position of A ring on the activity toward NF-kappaB-, AP-1-, or CREB-mediated transcription.
Journal: Bioorganic & medicinal chemistry letters 20080915
Title: [Studies on ethyl acetate soluble constituents of Huanglian Jiedutang].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901
Title: QSAR modeling of the interaction of flavonoids with GABA(A) receptor.
Journal: European journal of medicinal chemistry 20080801
Title: Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as alpha-glucosidase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20080301
Title: Saireito probably prevents mesangial cell proliferation in HIGA mice via PDGF-BB tyrosine kinase inhibition.
Journal: Clinical and experimental nephrology 20071201
Title: New dihydrochalcones and anti-platelet aggregation constituents from the leaves of Muntingia calabura.
Journal: Planta medica 20070601
Title: The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice.
Journal: Neurobiology of learning and memory 20070501
Title: Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats.
Journal: Archives of pharmacal research 20070201
Title: Oroxylin A induced apoptosis of human hepatocellular carcinoma cell line HepG2 was involved in its antitumor activity.
Journal: Biochemical and biophysical research communications 20061215
Title: Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061205
Title: Effect of the flavonoid, oroxylin A, on transient cerebral hypoperfusion-induced memory impairment in mice.
Journal: Pharmacology, biochemistry, and behavior 20061101
Title: Antioxidative and anti-inflammatory activities of polyhydroxyflavonoids of Scutellaria baicalensis GEORGI.
Journal: Bioscience, biotechnology, and biochemistry 20061001
Title: Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents.
Journal: Bioorganic & medicinal chemistry letters 20050901
Title: Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography.
Journal: Journal of chromatography. A 20050513
Title: 5,7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties.
Journal: Biochemical pharmacology 20030701
Title: Insect antifeedant activity of flavones and chromones against Spodoptera litura.
Journal: Journal of agricultural and food chemistry 20030115
Title: Antiviral Chinese medicinal herbs against respiratory syncytial virus.
Journal: Journal of ethnopharmacology 20020201
Title: Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana.
Journal: Journal of ethnopharmacology 19920401
Title: Zhao K, et al. Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells. J Hematol Oncol. 2015 Apr 23;8:41. http://www.ncbi.nlm.nih.gov/pubmed/25902914
Title: Dai Q, et al. Oroxylin A regulates glucose metabolism in response to hypoxic stress with the involvement of Hypoxia-inducible factor-1 in human hepatoma HepG2 cells. Mol Carcinog. 2015 Aug 10.
Title: Wei L, et al. Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization. Cell Death Dis. 2015 Apr 9
