Title: 27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes.
Journal: Toxicology and applied pharmacology 20140201
Title: Loading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterols.
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Title: Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells.
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Title: Inverse correlation between plasma oxysterol and LDL-cholesterol levels in hepatitis C virus-infected patients.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120301
Title: 7β-Hydroxycholesterol-induced energy stress leads to sequential opposing signaling responses and to death of C6 glioblastoma cells.
Journal: Biochemical pharmacology 20120101
Title: Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.
Journal: PloS one 20120101
Title: Selective cytotoxicity of oxysterols through structural modulation on rings A and B. Synthesis, in vitro evaluation, and SAR.
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Title: The effect of oxycholesterols on thermo-induced membrane dynamics.
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Title: Oxysterols direct B-cell migration through EBI2.
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Title: Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols.
Journal: Biochemical and biophysical research communications 20110617
Title: Biomarkers of oxidative damage in cigarette smokers: which biomarkers might reflect acute versus chronic oxidative stress?
Journal: Free radical biology & medicine 20110615
Title: Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.
Journal: Aging cell 20110601
Title: Relative contribution of individual oxidized components in ox-LDL to inhibition on endothelium-dependent relaxation in rat aorta.
Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20110301
Title: Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1.
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Title: Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate.
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Title: Isolation and identification of two steroid compounds from Oviductus Ranae.
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Title: Dansylation of unactivated alcohols for improved mass spectral sensitivity and application to analysis of cytochrome P450 oxidation products in tissue extracts.
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Title: Dimethyl sulfoxide prevents 7β-hydroxycholesterol-induced apoptosis by preserving lysosomes and mitochondria.
Journal: Journal of cardiovascular pharmacology 20100901
Title: Prevention of 7β-hydroxycholesterol-induced cell death by mangafodipir is mediated through lysosomal and mitochondrial pathways.
Journal: European journal of pharmacology 20100825
Title: The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice.
Journal: Neuroscience 20100811
Title: Cholesterol 7alpha-hydroxylase (CYP7A1) activity is modified after chronic ingestion of depleted uranium in the rat.
Journal: The Journal of steroid biochemistry and molecular biology 20100501
Title: Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands.
Journal: The Journal of biological chemistry 20100212
Title: Antiapoptotic and proliferative effects of low concentrations of 7β-hydroxycholesterol in human endothelial cells via ERK activation.
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Title: Effects of different rearing and feeding systems on lipid oxidation and antioxidant capacity of freeze-dried egg yolks.
Journal: Journal of agricultural and food chemistry 20091223
Title: 4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.
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Title: Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants.
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Title: Oxysterol-induced rearrangement of the liquid-ordered phase: a possible link to Alzheimer's disease?
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Title: Efficient chemoenzymatic synthesis, cytotoxic evaluation, and SAR of epoxysterols.
Journal: Journal of medicinal chemistry 20090709
Title: Increase of cholesterol oxidation and decrease of PUFA as a result of thermal processing and storage in eggs enriched with n-3 fatty acids.
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Title: Elucidation of functions of human cytochrome P450 enzymes: identification of endogenous substrates in tissue extracts using metabolomic and isotopic labeling approaches.
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Title: 7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent.
Journal: Cell biology and toxicology 20090401
Title: 7beta-hydroxycholesterol induces apoptosis and regulates cyclooxygenase 2 in head and neck squamous cell carcinoma.
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Title: Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS.
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Title: A single step solid-phase extraction method for complete separation of sterol oxidation products in food lipids.
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Title: Cathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosis.
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Title: 7beta-hydroxycholesterol induces natural killer cell death via oxidative lysosomal destabilization.
Journal: Free radical research 20090101
Title: The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide.
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Title: Oxysterol as a marker of atherogenic dyslipidemia in adolescence.
Journal: The Journal of clinical endocrinology and metabolism 20081101
Title: Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis.
Journal: Clinica chimica acta; international journal of clinical chemistry 20080901
Title: Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol.
Journal: Current eye research 20080901
Title: Effects of apigenin, lycopene and astaxanthin on 7 beta-hydroxycholesterol-induced apoptosis and Akt phosphorylation in U937 cells.
Journal: The British journal of nutrition 20080801
Title: Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation.
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Title: Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample.
Journal: Free radical biology & medicine 20080401
Title: Ox-LDL induces monocyte-to-macrophage differentiation in vivo: Possible role for the macrophage colony stimulating factor receptor (M-CSF-R).
Journal: Atherosclerosis 20080201
Title: Anthocyanin-rich Aronox extract from Aronia melanocarpa E protects against 7beta-hydroxycholesterol-induced apoptosis of endothelial cells.
Journal: Annals of nutrition & metabolism 20080101
Title: Degradation of 24S-hydroxycholesterol in men is not regulated by CYP7A1.
Journal: International journal of clinical pharmacology and therapeutics 20071101
Title: Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901
Title: In vivo interconversion of 7beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress.
Journal: Free radical biology & medicine 20070901
Title: Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease.
Journal: Clinica chimica acta; international journal of clinical chemistry 20070701
Title: Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase.
Journal: Journal of internal medicine 20070501
Title: Levels of lipid peroxidation in human plasma and erythrocytes: comparison between fatty acids and cholesterol.
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Title: Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol.
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Title: Effect of storage on cholesterol oxide formation and fatty acid alterations in egg powder.
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Title: Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy.
Journal: Free radical biology & medicine 20070301
Title: 25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages.
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Title: Oxidative status of human low density lipoprotein isolated by anion-exchange high-performance liquid chromatography--assessment by total hydroxyoctadecadienoic acid, 7-hydroxycholesterol, and 8-iso-prostaglandin F(2alpha).
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Title: Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus.
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Title: Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta-hydroxycholesterol triggered apoptosis in human colon cancer cells.
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Title: Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids.
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Title: Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide.
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Title: Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol.
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Title: Cytotoxicity of myeloperoxidase/nitrite-oxidized low-density lipoprotein toward endothelial cells is due to a high 7beta-hydroxycholesterol to 7-ketocholesterol ratio.
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Title: Formation of cholesterol oxidation products in marinated foods during heating.
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Title: Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms.
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Title: Species differences among various rodents in the conversion of 7alpha-hydroxycholesterol in liver microsomes.
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Title: Short-term hepatic effects of depleted uranium on xenobiotic and bile acid metabolizing cytochrome P450 enzymes in the rat.
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Title: Skeletal muscle and liver oxysterols during fasting and alcohol exposure.
Journal: Metabolism: clinical and experimental 20060101
Title: 7beta-hydroxycholesterol reduces the extent of reactive gliosis caused by iron deposition in the hippocampus but does not attenuate the iron-induced seizures in rats.
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Title: Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis.
Journal: International journal of toxicology 20060101
Title: An isocratic high-performance liquid chromatography assay for CYP7A1-catalyzed cholesterol 7alpha-hydroxylation.
Journal: Methods in molecular biology (Clifton, N.J.) 20060101
Title: High preoperative recipient plasma 7beta-hydroxycholesterol is associated with initial poor graft function after liver transplantation.
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Title: Combined effect of 25-hydroxycholesterol and IL-1beta on IL-8 production in human colon carcinoma cell line (Caco-2).
Journal: Inflammation 20051201
Title: 7-Ketocholesterol predisposes human aorta smooth muscle cells to Fas-mediated death.
Journal: Journal of molecular and cellular cardiology 20051101
Title: Foam cell death induced by 7beta-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma.
Journal: Free radical biology & medicine 20051001
Title: TNF-alpha activates death pathway in human aorta smooth muscle cell in the presence of 7-ketocholesterol.
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Title: Cytotoxic effect of 7beta-hydroxycholesterol on human NCI-H460 lung cancer cells.
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Journal: European journal of clinical investigation 20050801
Title: Effects of dietary fat and oxidized cholesterol on gene expression in rat liver as assessed by cDNA expression array analysis.
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Title: Effect of cholesterol and 7-beta hydroxycholesterol on glutathione status and nitric oxide production in murine peritoneal macrophages.
Journal: Indian journal of experimental biology 20050601
Title: A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis.
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Title: Cholesterol binding to cytochrome P450 7A1, a key enzyme in bile acid biosynthesis.
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Title: Different apoptotic mechanisms are involved in the antiproliferative effects of 7beta-hydroxysitosterol and 7beta-hydroxycholesterol in human colon cancer cells.
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Title: Baseline oxysterols and other markers of oxidative stress, inflammation and malnutrition in the vitamin e and intima media thickness progression in end-stage renal disease (VIPER) cohort.
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Title: Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study.
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Title: Enhanced expression of natural resistance-associated macrophage protein 1 in atherosclerotic lesions may be associated with oxidized lipid-induced apoptosis.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Does brain specific 24S-hydroxycholesterol in plasma indicate the disruption of the blood-brain barrier in patients with ischemic stroke?
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Title: Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol.
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Title: Detection of lipid peroxidation in vivo: total hydroxyoctadecadienoic acid and 7-hydroxycholesterol as oxidative stress marker.
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Title: Vitamin E is not deficient in human atherosclerotic plaques.
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Title: Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme.
Journal: The Journal of biological chemistry 20040430
Title: Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: implications for proatherogenic gene modulation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040401
Title: Application of water-soluble radical initiator, 2,2'-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride, to a study of oxidative stress.
Journal: Free radical research 20040401
Title: Effect of cholesterol and 7beta-hydroxycholesterol on glutathione status and expression of Hsp70 in cultured murine peritoneal macrophages.
Journal: Indian journal of biochemistry & biophysics 20040201
Title: Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040101
Title: Generation of an oxidative stress precedes caspase activation during 7beta-hydroxycholesterol-induced apoptosis in U937 cells.
Journal: Journal of biochemical and molecular toxicology 20040101
Title: New internal standard for quantitative determination of oxyphytosterols by gas chromatography.
Journal: Journal of AOAC International 20040101
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Journal: Biological research 20040101
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Title: Serum ferritin concentration is associated with plasma levels of cholesterol oxidation products in man.
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Title: Synthesis of deuterated isotopomers of 7alpha- and (25R,S)-26-hydroxycholesterol, internal standards for in vivo determination of the two biosynthetic pathways of bile acids.
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Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20030701
Title: Lysophosphatidylcholine regulates synthesis of biglycan and the proteoglycan form of macrophage colony stimulating factor.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030501
Title: Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate.
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Title: Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis.
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Journal: International journal of food sciences and nutrition 20020901
Title: Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals.
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Title: A comparative study of the conversion of 7-hydroxycholesterol in rabbit, guinea pig, rat, hamster, and chicken.
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Title: Characteristics of 7 beta-hydroxycholesterol-induced cell death in a human monocytic blood cell line, U937, and a human hepatoma cell line, HepG2.
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Title: Effects of combinations of 7beta-hydroxycholesterol and anticancer drugs or ionizing radiation on the proliferation of cultured tumor cells.
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Title: Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.
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Journal: American journal of physiology. Gastrointestinal and liver physiology 20011001
Title: Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products.
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Title: Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans.
Journal: Hepatology (Baltimore, Md.) 20010801
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Title: Influence of 7beta-hydroxycholesterol on glutathione status and nitric oxide production in macrophages: in vitro studies.
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Title: Fas/Fas ligand-mediated death pathway is involved in oxLDL-induced apoptosis in vascular smooth muscle cells.
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Title: Formation of cholesterol oxides in irradiated raw and cooked chicken meat during storage.
Journal: Poultry science 20010101
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Journal: Cell death and differentiation 20010101
Title: Effect of 7beta-hydroxycholesterol on cellular redox status and heat shock protein 70 expression in macrophages.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101
Title: Oxysterols, but not cholesterol, inhibit human immunodeficiency virus replication in vitro.
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