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63223-86-9,MFCD09951797
Catalog No.:AA00IB3H

63223-86-9 | Ginsenoside rh1

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5mg
98% by HPLC
in stock  
$110.00   $77.00
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10mg
98% by HPLC
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$142.00   $99.00
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25mg
98% by HPLC
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$228.00   $160.00
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50mg
98% by HPLC
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$343.00   $240.00
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100mg
98% by HPLC
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$547.00   $383.00
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500mg
98% by HPLC
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$1,622.00   $1,136.00
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1000mg
98% by HPLC
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$2,557.00   $1,790.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IB3H
Chemical Name:
Ginsenoside rh1
CAS Number:
63223-86-9
Molecular Formula:
C36H62O9
Molecular Weight:
638.8721
MDL Number:
MFCD09951797
SMILES:
OC[C@H]1O[C@@H](O[C@H]2C[C@]3(C)[C@@H]([C@@]4([C@@H]2C(C)(C)[C@@H](O)CC4)C)C[C@H]([C@H]2[C@@]3(C)CC[C@@H]2[C@](CCC=C(C)C)(O)C)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Properties
 
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
1110  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
16  
Heavy Atom Count:
45  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
7  
XLogP3:
4.3  

Literature

Title: Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype.

Journal: Chemico-biological interactions 20180301

Title: Effect of ginsenoside Rh1 on myocardial injury and heart function in isoproterenol-induced cardiotoxicity in rats.

Journal: Toxicology mechanisms and methods 20121001

Title: Antibiotics attenuate anti-scratching behavioral effect of ginsenoside Re in mice.

Journal: Journal of ethnopharmacology 20120626

Title: Ginsenoside Rh1 suppresses matrix metalloproteinase-1 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathway in human hepatocellular carcinoma cells.

Journal: European journal of pharmacology 20120315

Title: Ginsenoside metabolite compound K differentially antagonizing tumor necrosis factor-α-induced monocyte-endothelial trafficking.

Journal: Chemico-biological interactions 20111015

Title: A novel ginsenosidase from an Aspergillus strain hydrolyzing 6-O-multi-glycosides of protopanaxatriol-type ginsenosides, named ginsenosidase type IV.

Journal: Journal of microbiology and biotechnology 20111001

Title: Ginsenoside Rh1 inhibits the invasion and migration of THP-1 acute monocytic leukemia cells via inactivation of the MAPK signaling pathway.

Journal: Fitoterapia 20110901

Title: Oral administration of ginsenoside Rh1 inhibits the development of atopic dermatitis-like skin lesions induced by oxazolone in hairless mice.

Journal: International immunopharmacology 20110401

Title: Anti-inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide-stimulated microglia: critical role of the protein kinase A pathway and hemeoxygenase-1 expression.

Journal: Journal of neurochemistry 20101201

Title: Ginsenoside Rh1 suppresses inducible nitric oxide synthase gene expression in IFN-gamma-stimulated microglia via modulation of JAK/STAT and ERK signaling pathways.

Journal: Biochemical and biophysical research communications 20100625

Title: [Pharmacokinetics of ginsenosides Rg1 and its metabolites in rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100501

Title: [Determination and enzymolysis preparation of ginsenoside Rh1].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

Title: Biotransformation of ginsenoside Rf to Rh1 by recombinant beta-glucosidase.

Journal: Molecules (Basel, Switzerland) 20090608

Title: Characterization of pharmacokinetic profiles and metabolic pathways of 20(S)-ginsenoside Rh1 in vivo and in vitro.

Journal: Planta medica 20090601

Title: Improvement of memory in mice and increase of hippocampal excitability in rats by ginsenoside Rg1's metabolites ginsenoside Rh1 and protopanaxatriol.

Journal: Journal of pharmacological sciences 20090401

Title: Determination of 20(S)-ginsenoside Rh1 and its aglycone 20(S)-protopanaxatriol in rat plasma by sensitive LC-APCI-MS method and its application to pharmacokinetic study.

Journal: European journal of mass spectrometry (Chichester, England) 20090101

Title: [A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20081201

Title: Protective effect of ginsenosides Rg(2) and Rh(1) on oxidation-induced impairment of erythrocyte membrane properties.

Journal: Biorheology 20080101

Title: [Studies on chemical constituents from rhizomes of Panax notoginseng].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071101

Title: Microbial transformation of 20(S)-protopanaxatriol-type saponins by Absidia coerulea.

Journal: Journal of natural products 20070701

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: The effects of ginsenoside Re and its metabolite, ginsenoside Rh1, on 12-O-tetradecanoylphorbol 13-acetate- and oxazolone-induced mouse dermatitis models.

Journal: Planta medica 20060301

Title: Influence of ginsenoside Rh1 and F1 on human cytochrome p450 enzymes.

Journal: Planta medica 20060201

Title: Metabolism of ginsenoside Re by human intestinal microflora and its estrogenic effect.

Journal: Biological & pharmaceutical bulletin 20051001

Title: Simultaneous rapid quantification of ginsenoside Rg1 and its secondary glycoside Rh1 and aglycone protopanaxatriol in rat plasma by liquid chromatography-mass spectrometry after solid-phase extraction.

Journal: Journal of pharmaceutical and biomedical analysis 20050601

Title: Ginsenoside Rh1 possesses antiallergic and anti-inflammatory activities.

Journal: International archives of allergy and immunology 20040201

Title: Degradation of ginsenosides in humans after oral administration.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030801

Title: Structures of new dammarane-type Triterpene Saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal Ginseng Saponins.

Journal: Journal of natural products 20030701

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1.

Journal: Chemical & pharmaceutical bulletin 20030401

Title: Enzymatic preparation of ginsenosides Rg2, Rh1, and F1 from protopanaxatriol-type ginseng saponin mixture.

Journal: Planta medica 20030301

Title: A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells.

Journal: The Journal of steroid biochemistry and molecular biology 20030301

Title: [Saponins with low sugar chain from the leaves of Panax notoginseng (Burk) F. H. Chen].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20020301

Title: Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity.

Journal: Journal of natural products 20010401

Title: Ginsenosides increase secretion of lipoprotein lipase by 3T3-L1 adipocytes.

Journal: Bioscience, biotechnology, and biochemistry 19961201

Title: Gu W, et al. Ginsenoside Rh1 ameliorates high fat diet-induced obesity in mice by inhibiting adipocyte differentiation. Biol Pharm Bull. 2013;36(1):102-7.

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