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67-73-2,MFCD00010525
Catalog No.:AA0034UR

67-73-2 | Fluocinolone acetonide

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100mg
in stock  
$147.00   $103.00
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500mg
≥98%
in stock  
$152.00   $106.00
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1g
≥98%
in stock  
$283.00   $198.00
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5g
≥98%
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$815.00   $570.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0034UR
Chemical Name:
Fluocinolone acetonide
CAS Number:
67-73-2
Molecular Formula:
C24H30F2O6
Molecular Weight:
452.4882
MDL Number:
MFCD00010525
SMILES:
OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)(C)C
NSC Number:
92339
Properties
Properties
 
Form:
Solid  
MP:
267-269 °C(lit.)  
Refractive Index:
103 ° (C=1, MeOH)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
960  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
2.5  

Literature

Title: Safety and efficacy of fluocinolone acetonide intravitreal implant (0.59 mg) in birdshot retinochoroidopathy.

Journal: Retina (Philadelphia, Pa.) 20141101

Title: Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema.

Journal: Ophthalmology 20121001

Title: Corticosteroid use for diabetic macular edema: old fad or new trend?

Journal: Current diabetes reports 20120801

Title: Intraocular corticosteroids for posterior segment disease: 2012 update.

Journal: Expert opinion on pharmacotherapy 20120801

Title: Trends in older adult psoriasis outpatient health care practices in the United States.

Journal: Journal of drugs in dermatology : JDD 20120801

Title: Nebulized corticosteroids in asthma and COPD. An Italian appraisal.

Journal: Respiratory care 20120701

Title: Combined posterior chamber intraocular lens, vitrectomy, Retisert, and pars plana tube in noninfectious uveitis.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20120701

Title: [Clinical signs of Cushing's syndrome after long-term local application of steroid in the oral cavity].

Journal: Ugeskrift for laeger 20120625

Title: Preventing melasma recurrence: prescribing a maintenance regimen with an effective triple combination cream based on long-standing clinical severity.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20120501

Title: [The diabetic macular edema--new possibilities of the treatment].

Journal: Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20120501

Title: Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants.

Journal: The Cochrane database of systematic reviews 20120418

Title: Spontaneous resolution of intravitreal steroid-induced bilateral cytomegalovirus retinitis.

Journal: Korean journal of ophthalmology : KJO 20120401

Title: Treatment of intractable posterior uveitis in pediatric patients with the fluocinolone acetonide intravitreal implant (Retisert).

Journal: Retina (Philadelphia, Pa.) 20120301

Title: Associations among visual acuity and vision- and health-related quality of life among patients in the multicenter uveitis steroid treatment trial.

Journal: Investigative ophthalmology & visual science 20120301

Title: Incorporation of anti-inflammatory agent into calcium hydroxide pulp capping material: an in vitro study of physical and mechanical properties.

Journal: Dental materials journal 20120203

Title: Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action.

Journal: Annals of dermatology 20120201

Title: A PAMPA assay as fast predictive model of passive human skin permeability of new synthesized corticosteroid C-21 esters.

Journal: Molecules (Basel, Switzerland) 20120105

Title: Prospective study of a fluocinolone acetonide implant for chronic macular edema from central retinal vein occlusion: thirty-six-month results.

Journal: Ophthalmology 20120101

Title: Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration.

Journal: Biomaterials 20120101

Title: Scleral thickness in human eyes.

Journal: PloS one 20120101

Title: Post-cataract outcomes in patients with noninfectious posterior uveitis treated with the fluocinolone acetonide intravitreal implant.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Update on sympathetic ophthalmia.

Journal: Middle East African journal of ophthalmology 20120101

Title: EMBO Retinoids 2011: Mechanisms, biology and pathology of signaling by retinoic acid and retinoic acid receptors.

Journal: Nuclear receptor signaling 20120101

Title: Emerging pharmacotherapies for diabetic macular edema.

Journal: Experimental diabetes research 20120101

Title: Recurrent acute rhinosinusitis: a single blind clinical study of N-acetylcysteine vs ambroxol associated to corticosteroid therapy.

Journal: International journal of immunopathology and pharmacology 20120101

Title: Corticosteroid intravitreal implants.

Journal: Developments in ophthalmology 20120101

Title: Win percentage: a novel measure for assessing the suitability of machine classifiers for biological problems.

Journal: BMC bioinformatics 20120101

Title: Long-term results of oral valganciclovir for treatment of anterior segment inflammation secondary to cytomegalovirus infection.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Triple combination and glycolic peels in post-acne hyperpigmentation.

Journal: Journal of cutaneous and aesthetic surgery 20120101

Title: Cytomegalovirus retinitis after central retinal vein occlusion in a patient on systemic immunosuppression: does venooclusive disease predispose to cytomegalovirus retinitis in patients already at risk?

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Necrotizing keratitis after laser refractive surgery in patients with inactive inflammatory bowel disease.

Journal: Case reports in ophthalmology 20120101

Title: Oral lichen planus as a preneoplastic inflammatory model.

Journal: Journal of biomedicine & biotechnology 20120101

Title: Intravitreal devices for the treatment of vitreous inflammation.

Journal: Mediators of inflammation 20120101

Title: Identifying a clinically meaningful threshold for change in uveitic macular edema evaluated by optical coherence tomography.

Journal: American journal of ophthalmology 20111201

Title: Challenges in the design and implementation of the Multicenter Uveitis Steroid Treatment (MUST) Trial--lessons for comparative effectiveness trials.

Journal: Clinical trials (London, England) 20111201

Title: Emerging drugs for diabetic retinopathy.

Journal: Expert opinion on emerging drugs 20111201

Title: Presumed necrotizing viral retinitis after intravitreal triamcinolone injection: case report.

Journal: Korean journal of ophthalmology : KJO 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Pars plana vitrectomy, fluocinolone acetonide implantation, and silicone oil infusion for the treatment of chronic, refractory uveitic hypotony.

Journal: American journal of ophthalmology 20111101

Title: Review and update of intraocular therapy in noninfectious uveitis.

Journal: Current opinion in ophthalmology 20111101

Title: Antitumor effect of non-steroid glucocorticoid receptor ligand CpdA on leukemia cell lines CEM and K562.

Journal: Biochemistry. Biokhimiia 20111101

Title: Combined use of algorithms for peak picking, peak tracking and retention modelling to optimize the chromatographic conditions for liquid chromatography-mass spectrometry analysis of fluocinolone acetonide and its degradation products.

Journal: Analytica chimica acta 20111017

Title: Intraocular pressure outcome of patients with fluocinolone acetonide intravitreal implant for noninfectious uveitis.

Journal: Ophthalmology 20111001

Title: Assessment and management of chronic otitis externa.

Journal: Current opinion in otolaryngology & head and neck surgery 20111001

Title: Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: the multicenter uveitis steroid treatment trial.

Journal: Ophthalmology 20111001

Title: Hyalinization of the pyloric stomach in CD-1 mice following oral (dietary) administration of the corticosteroid agonists mometasone furoate, budesonide, and flunisolide.

Journal: Toxicologic pathology 20111001

Title: Linear growth and bone maturation are unaffected by 1 year of therapy with inhaled flunisolide hydrofluoroalkane in prepubescent children with mild persistent asthma: a randomized, double-blind, placebo-controlled trial.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20111001

Title: Sustained release intraocular drug delivery devices for treatment of uveitis.

Journal: Journal of ophthalmic & vision research 20111001

Title: Melasma treatment with pulsed-dye laser and triple combination cream: a prospective, randomized, single-blind, split-face study.

Journal: Archives of dermatology 20110901

Title: Validation of a photographic vitreous haze grading technique for clinical trials in uveitis.

Journal: American journal of ophthalmology 20110801

Title: Morphologic assessment for glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) trial.

Journal: Ocular immunology and inflammation 20110801

Title: Cytomegalovirus endotheliitis after fluocinolone acetonide (Retisert) implant in a patient with Behçet uveitis.

Journal: Ocular immunology and inflammation 20110801

Title: Fluocinolone acetonide intravitreal implant for diabetic macular edema: a 3-year multicenter, randomized, controlled clinical trial.

Journal: Ophthalmology 20110801

Title: Therapeutic Index (TIX) for intranasal corticosteroids in the treatment of allergic rhinitis.

Journal: Rhinology 20110801

Title: Treatment outcome of Paederus dermatitis due to rove beetles (Coleoptera: Staphylinidae) on guinea pigs.

Journal: Tropical biomedicine 20110801

Title: Sustained-release intravitreal liquid drug delivery using triamcinolone acetonide for cystoid macular edema in retinal vein occlusion.

Journal: Ophthalmology 20110701

Title: Trabecular meshwork and lens partitioning of corticosteroids: implications for elevated intraocular pressure and cataracts.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20110701

Title: Fluocinolone acetonide implant (Retisert) for chronic cystoid macular edema in two patients with AIDS and a history of cytomegalovirus retinitis.

Journal: Ocular immunology and inflammation 20110601

Title: A functional, nonfunctioning Retisert implant.

Journal: Ocular immunology and inflammation 20110601

Title: Use of a high infusion rate to prevent posterior dislocation of fluocinolone acetonide implant during surgical removal.

Journal: Ocular immunology and inflammation 20110601

Title: Activities of aldo-keto reductase 1 enzymes on two inhaled corticosteroids: implications for the pharmacological effects of inhaled corticosteroids.

Journal: Chemico-biological interactions 20110530

Title: Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110501

Title: Dexamethasone for ocular inflammation.

Journal: Expert opinion on pharmacotherapy 20110501

Title: Photoactivation of corticosteroids in UVB-exposed skin.

Journal: Journal of photochemistry and photobiology. B, Biology 20110404

Title: Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema.

Journal: Ophthalmology 20110401

Title: Investigation of solvolysis kinetics of new synthesized fluocinolone acetonide C-21 esters--an in vitro model for prodrug activation.

Journal: Molecules (Basel, Switzerland) 20110323

Title: Fluocinolone acetonide implantable device for diabetic retinopathy.

Journal: Current pharmaceutical biotechnology 20110301

Title: Triple combination and glycolic acid peels in melasma in Indian patients.

Journal: Journal of cosmetic dermatology 20110301

Title: [Intravitreal implants: drug carriers and carriers of hope?].

Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20110301

Title: Herpetic necrotizing retinitis following flucinolone acetonide intravitreal implant.

Journal: Ocular immunology and inflammation 20110201

Title: Effect of fluocinolone acetonide on human dental pulp cells: cytotoxicity, proliferation, and extracellular matrix formation.

Journal: Journal of endodontics 20110201

Title: Sequential treatment with triple combination cream and intense pulsed light is more efficacious than sequential treatment with an inactive (control) cream and intense pulsed light in patients with moderate to severe melasma.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20110201

Title: Low-fluence Q-switched neodymium-doped yttrium aluminum garnet laser for melasma with pre- or post-treatment triple combination cream.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20110101

Title: Intranasal flunisolide treatment in patients with non-allergic rhinitis.

Journal: International journal of immunopathology and pharmacology 20110101

Title: Inflammatory glaucoma.

Journal: Oman journal of ophthalmology 20110101

Title: Biocompatibility and biodegradation studies of subconjunctival implants in rabbit eyes.

Journal: PloS one 20110101

Title: Alopecia: evaluation and treatment.

Journal: Clinical, cosmetic and investigational dermatology 20110101

Title: Alopecia areata: a new treatment plan.

Journal: Clinical, cosmetic and investigational dermatology 20110101

Title: A new paleozoic Symmoriiformes (Chondrichthyes) from the late Carboniferous of Kansas (USA) and cladistic analysis of early chondrichthyans.

Journal: PloS one 20110101

Title: Dexamethasone intravitreal implant for the treatment of noninfectious uveitis.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Atopic dermatitis.

Journal: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20110101

Title: Nanotechnology and nanotoxicology in retinopathy.

Journal: International journal of molecular sciences 20110101

Title: A study of pathogenesis of acanthosis nigricans and its clinical implications.

Journal: Indian journal of dermatology 20110101

Title: Combination therapies in ophthalmology: implications for intravitreal delivery.

Journal: Journal of ophthalmic & vision research 20110101

Title: 'For export only' medicines come back to Europe: a RP-LC method for the screening of six glucocorticoids in illegal and counterfeit anti-inflammatory and lightening creams.

Journal: Journal of pharmaceutical and biomedical analysis 20101010

Title: Cost-effectiveness of a hydroquinone/tretinoin/fluocinolone acetonide cream combination in treating melasma in the United States.

Journal: The Journal of dermatological treatment 20100901

Title: Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period.

Journal: European journal of clinical pharmacology 20100901

Title: Recent advances in ophthalmic drug delivery.

Journal: Therapeutic delivery 20100901

Title: Intravitreous delivery of the corticosteroid fluocinolone acetonide attenuates retinal degeneration in S334ter-4 rats.

Journal: Investigative ophthalmology & visual science 20100801

Title: Scleral thickness following fluocinolone acetonide implant (Retisert).

Journal: Ocular immunology and inflammation 20100801

Title: Interventions for melasma.

Journal: The Cochrane database of systematic reviews 20100707

Title: The effect of a preoperative subconjuntival injection of dexamethasone on blood-retinal barrier breakdown following scleral buckling retinal detachment surgery: a prospective randomized placebo-controlled double blind clinical trial.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100701

Title: Sustained ocular delivery of fluocinolone acetonide by an intravitreal insert.

Journal: Ophthalmology 20100701

Title: Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework.

Journal: Bioinformatics (Oxford, England) 20100615

Title: Low-fluence Q-switched neodymium-doped yttrium aluminum garnet laser for melasma with pre- or post-treatment triple combination cream.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20100601

Title: Continuous therapy followed by a maintenance therapy regimen with a triple combination cream for melasma.

Journal: Journal of the American Academy of Dermatology 20100601

Title: The clinical utility of a hand-held computerized optical imaging system at assessing skin discoloration.

Journal: Journal of cosmetic dermatology 20100601

Title: Combined fluocinolone acetonide intravitreal insertion and glaucoma drainage device placement for chronic uveitis and glaucoma.

Journal: American journal of ophthalmology 20100501

Title: Proof of concept for combined insertion of fluocinolone acetonide and glaucoma drainage implants for eyes with uveitis and glaucoma.

Journal: American journal of ophthalmology 20100501

Title: Modulation by flunisolide of tumor necrosis factor-alpha-induced stimulation of airway epithelial cell activities related to eosinophil inflammation.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 20100501

Title: Use of ozone-depleting substances; removal of essential-use designation (flunisolide, etc.). Final rule.

Journal: Federal register 20100414

Title: The multicenter uveitis steroid treatment trial: rationale, design, and baseline characteristics.

Journal: American journal of ophthalmology 20100401

Title: Evaluation of an intravitreal fluocinolone acetonide implant versus standard systemic therapy in noninfectious posterior uveitis.

Journal: Ophthalmology 20100301

Title: An application of second-order UV-derivative spectrophotometry for study of solvolysis of a novel fluocinolone acetonide ester.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100201

Title: Biodegradable intraocular therapies for retinal disorders: progress to date.

Journal: Drugs & aging 20100201

Title: Cytomegalovirus endotheliitis following fluocinolone acetonide (Retisert) implant.

Journal: Eye (London, England) 20100101

Title: Juvenile bullous pemphigoid: the presentation and follow-up of six cases.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20100101

Title: Current approach in the diagnosis and management of posterior uveitis.

Journal: Indian journal of ophthalmology 20100101

Title: The evolving role of therapeutic shampoos for targeting symptoms of inflammatory scalp disorders.

Journal: Journal of drugs in dermatology : JDD 20100101

Title: Oral lichenoid drug reaction associated with antihypertensive and hypoglycemic drugs.

Journal: Journal of drugs in dermatology : JDD 20100101

Title: Optimal management of cytomegalovirus retinitis in patients with AIDS.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Management of alopecia areata.

Journal: BMJ (Clinical research ed.) 20100101

Title: Antiretroviral Drug-Associated Oral Lichenoid Reaction in HIV Patient: A Case Report.

Journal: International journal of dentistry 20100101

Title: Differentiating intraocular glucocorticoids.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20100101

Title: New developments in corticosteroid therapy for uveitis.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20100101

Title: Drug delivery options for the treatment of ocular inflammation.

Journal: Seminars in ophthalmology 20100101

Title: Treatment of noninfectious posterior uveitis with dexamethasone intravitreal implant.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20100101

Title: Levels of salivary IFN-gamma, TNF-alfa, and TNF receptor-2 as prognostic markers in (erosive) oral lichen planus.

Journal: Mediators of inflammation 20100101

Title: Mometasone-based triple combination therapy in melasma: is it really safe?

Journal: Indian journal of dermatology 20100101

Title: Desipramine inhibits the growth of a mouse skin squamous cell carcinoma cell line and affects glucocorticoid receptor-mediated transcription.

Journal: Molecular carcinogenesis 20091201

Title: A histological examination for skin atrophy after 6 months of treatment with fluocinolone acetonide 0.01%, hydroquinone 4%, and tretinoin 0.05% cream.

Journal: The American Journal of dermatopathology 20091201

Title: The role of spirituality healing with perceptions of the medical encounter among Latinos.

Journal: Journal of general internal medicine 20091101

Title: Photoreceptor neuroprotection in RCS rats via low-dose intravitreal sustained-delivery of fluocinolone acetonide.

Journal: Investigative ophthalmology & visual science 20091001

Title: Expression of IFN-gamma before and after treatment of oral lichen planus with 0.1% fluocinolone acetonide in orabase.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20091001

Title: Hyperpigmentation: old problem, new therapies.

Journal: Journal of drugs in dermatology : JDD 20090901

Title: Management of fluocinolone implant dissociation during implant exchange.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20090901

Title: Endogenous tenascin-C enhances glioblastoma invasion with reactive change of surrounding brain tissue.

Journal: Cancer science 20090801

Title: Melasma in Latin America: options for therapy and treatment algorithm.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20090701

Title: The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids.

Journal: The Journal of allergy and clinical immunology 20090601

Title: Effect of phosphodiesterase antagonists on glucocorticoid mediated growth inhibition in murine skin cell lines.

Journal: European journal of pharmacology 20090521

Title: Improvement of idiopathic acanthosis nigricans with a triple combination depigmenting cream.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20090401

Title: Targetoid pattern of hair regrowth in alopecia areata: a case report.

Journal: Clinical and experimental dermatology 20090401

Title: Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-alpha-induced angiogenesis in chick chorioallantoic membrane (CAM).

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090401

Title: Lymph node assessment: issues in pathology.

Journal: Journal of surgical oncology 20090315

Title: Promotion of mouse two-stage skin carcinogenesis by diacylglycerol-rich edible oil.

Journal: Cancer letters 20090308

Title: Management of sympathetic ophthalmia with the fluocinolone acetonide implant.

Journal: Ophthalmology 20090301

Title: Prevalence and management of elevated intraocular pressure after placement of an intravitreal sustained-release steroid implant.

Journal: Current opinion in ophthalmology 20090301

Title: Intravitreal inserts of steroids to treat diabetic macular edema.

Journal: Current diabetes reviews 20090201

Title: Uveitis treated with fluocinolone acetonide implants.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20090101

Title: Validation of a solid-phase extraction and ultra-performance liquid chromatographic tandem mass spectrometric method for the detection of 16 glucocorticoids in pig tissues.

Journal: Journal of AOAC International 20090101

Title: The role of topical retinoids in the treatment of pigmentary disorders: an evidence-based review.

Journal: American journal of clinical dermatology 20090101

Title: Primary treatment of diabetic macular edema.

Journal: Clinical interventions in aging 20090101

Title: High-dose inhaled flunisolide versus budesonide in the treatment of acute asthma exacerbations in preschool-age children.

Journal: International journal of immunopathology and pharmacology 20090101

Title: Overall and cancer related mortality among patients with ocular inflammation treated with immunosuppressive drugs: retrospective cohort study.

Journal: BMJ (Clinical research ed.) 20090101

Title: Prevention of surgery in children with adenoidal hypertrophy treated with intranasal flunisolide: a 12-month follow-up.

Journal: Journal of biological regulators and homeostatic agents 20090101

Title: Fluocinolone acetonide 0.01% in peanut oil: safety and efficacy data in the treatment of childhood atopic dermatitis in infants as young as 3 months of age.

Journal: Pediatric dermatology 20090101

Title: Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells.

Journal: BMC medical genomics 20090101

Title: Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.

Journal: PloS one 20090101

Title: Fluocinolone acetonide intravitreal implants in Vogt-Koyanagi-Harada disease.

Journal: Ocular immunology and inflammation 20090101

Title: Triple combination of hydroquinone, tretinoin and mometasone furoate with glycolic acid peels in melasma.

Journal: Indian journal of dermatology 20090101

Title: Topical treatment of melasma.

Journal: Indian journal of dermatology 20090101

Title: Etiology and treatment of the inflammatory causes of cystoid macular edema.

Journal: Journal of inflammation research 20090101

Title: Cystoid macular edema.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20081201

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: Successful treatment of moderate to severe melasma with triple-combination cream and glycolic acid peels: a pilot study.

Journal: Cutis 20081101

Title: Chronic cutaneous lupus erythematosus in vitiligo.

Journal: Dermatology online journal 20081015

Title: Outcome of fluocinolone acetonide implant (Retisert) reimplantation for chronic noninfectious posterior uveitis.

Journal: Retina (Philadelphia, Pa.) 20081001

Title: Combined fluocinolone acetonide intraocular delivery system insertion, phacoemulsification, and intraocular lens implantation for severe uveitis.

Journal: American journal of ophthalmology 20081001

Title: Immune system and inflammation.

Journal: Indian journal of pharmacology 20081001

Title: A randomized controlled trial of the efficacy and safety of a fixed triple combination (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) compared with hydroquinone 4% cream in Asian patients with moderate to severe melasma.

Journal: The British journal of dermatology 20080901

Title: Iluvien: a new sustained delivery technology for posterior eye disease.

Journal: Expert opinion on drug delivery 20080901

Title: Treatment of posterior uveitis with a fluocinolone acetonide implant: three-year clinical trial results.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20080901

Title: Fluocinolone acetonide for the treatment of uveitis: weighing the balance between local and systemic immunosuppression.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20080901

Title: Fluocinolone acetonide sustained drug delivery device for chronic central retinal vein occlusion: 12-month results.

Journal: American journal of ophthalmology 20080801

Title: Cytomegalovirus retinitis after intravitreous triamcinolone injection in a patient with central retinal vein occlusion.

Journal: Korean journal of ophthalmology : KJO 20080601

Title: Current and future approaches in the prevention and treatment of diabetic retinopathy.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20080601

Title: Efalizumab: results of a 3-year continuous dosing study for the long-term control of psoriasis.

Journal: The British journal of dermatology 20080501

Title: Update on treatments for diabetic macular edema.

Journal: Current opinion in ophthalmology 20080501

Title: Nebulisation of corticosteroid suspensions and solutions with a beta(2) agonist.

Journal: The Journal of pharmacy and pharmacology 20080501

Title: Partitioning of anti-inflammatory steroid drugs into phosphatidylcholine and phosphatidylcholine-cholesterol small unilamellar vesicles as studied by second-derivative spectrophotometry.

Journal: Chemical & pharmaceutical bulletin 20080501

Title: Reimplantation of a fluocinolone acetonide sustained drug delivery implant for chronic uveitis.

Journal: American journal of ophthalmology 20080401

Title: Subcutaneous emphysema caused by cryotherapy application over a corticosteroid-induced atrophic skin.

Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20080401

Title: Lichenoid and other clinical presentations of atopic dermatitis in an inner city practice.

Journal: Journal of the American Academy of Dermatology 20080301

Title: Intravitreal steroids for macular edema in diabetes.

Journal: The Cochrane database of systematic reviews 20080123

Title: Diabetic retinopathy: an update.

Journal: Indian journal of ophthalmology 20080101

Title: Treatment of serpiginous choroiditis with intravitreous fluocinolone acetonide implant.

Journal: Ocular immunology and inflammation 20080101

Title: PSivida corporation.

Journal: Arzneimittel-Forschung 20080101

Title: Intravitreal steroid slow-release device replacing repeated intravitreal triamcinolone injections for sympathetic ophthalmia.

Journal: European journal of ophthalmology 20080101

Title: Use of intravitreal triamcinolone in the treatment of macular edema related to retinal vein occlusion.

Journal: The open ophthalmology journal 20080101

Title: Injectable, in situ forming poly(propylene fumarate)-based ocular drug delivery systems.

Journal: Journal of biomedical materials research. Part A 20071201

Title: Epithelial cells in the hair follicle bulge do not contribute to epidermal regeneration after glucocorticoid-induced cutaneous atrophy.

Journal: The Journal of investigative dermatology 20071201

Title: Stem cells in the hair follicle and interfollicular epidermis of mice following topical application of fluocinolone acetonide.

Journal: The Journal of investigative dermatology 20071201

Title: An efficacy study of 3 commercially available hydroquinone 4% treatments for melasma.

Journal: Cutis 20071201

Title: Pharmacologic therapies for diabetic retinopathy and diabetic macular edema.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20071201

Title: Intraocular pressure in patients with uveitis treated with fluocinolone acetonide implants.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20071101

Title: Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects.

Journal: Respiratory medicine 20070701

Title: Vitreous band formation and the sustained-release, intravitreal fluocinolone (Retisert) implant.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20070601

Title: Drug delivery methods for posterior segment disease.

Journal: Current opinion in ophthalmology 20070501

Title: Hypertrichosis as a side effect of inhaled steroids in children.

Journal: Pediatric pulmonology 20070401

Title: Retisert: is the new advance in treatment of uveitis a good one?

Journal: The Annals of pharmacotherapy 20070301

Title: A comparison of triple combination cream and hydroquinone 4% cream for the treatment of moderate to severe facial melasma.

Journal: Journal of cosmetic dermatology 20070301

Title: Fluocinolone acetonide intravitreal sustained release device--a new addition to the armamentarium of uveitic management.

Journal: International journal of nanomedicine 20070301

Title: Cytomegalovirus retinitis after fluocinolone acetonide (Retisert) implant.

Journal: American journal of ophthalmology 20070201

Title: Cost-effectiveness of a fixed combination of hydroquinone/tretinoin/fluocinolone cream compared with hydroquinone alone in the treatment of melasma.

Journal: Journal of drugs in dermatology : JDD 20070201

Title: Emerging therapies for the treatment of neovascular age-related macular degeneration and diabetic macular edema.

Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20070101

Title: Pharmacotherapies for diabetic retinopathy: present and future.

Journal: Experimental diabetes research 20070101

Title: Compressor/nebulizers differences in the nebulization of corticosteroids. The CODE study (Corticosteroids and Devices Efficiency).

Journal: European review for medical and pharmacological sciences 20070101

Title: A reappraisal of the clinical efficacy of nebulized flunisolide in pediatric asthma: the Italian experience.

Journal: Allergy and asthma proceedings 20070101

Title: Intranasal flunisolide treatment in children with adenoidal hypertrophy.

Journal: International journal of immunopathology and pharmacology 20070101

Title: Corticosteroid therapy in the treatment of pediatric patients with atopic dermatitis.

Journal: GMS health technology assessment 20070101

Title: Intravitreal steroids in the management of macular oedema.

Journal: Acta ophthalmologica Scandinavica 20061201

Title: Ethnic considerations in the treatment of Hispanic and Latin-American patients with hyperpigmentation.

Journal: The British journal of dermatology 20061201

Title: Validation of a melasma quality of life questionnaire for Brazilian Portuguese language: the MelasQoL-BP study and improvement of QoL of melasma patients after triple combination therapy.

Journal: The British journal of dermatology 20061201

Title: [New drugs in the treatment of noninfectious uveitis].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20061201

Title: Topical glucocorticosteroids in rhinitis: clinical aspects.

Journal: Acta oto-laryngologica 20061001

Title: Treating chronic noninfectious posterior segment uveitis: the impact of cumulative damage. Proceedings of an expert panel roundtable discussion.

Journal: Retina (Philadelphia, Pa.) 20061001

Title: Long-term release of fluocinolone acetonide using biodegradable fumarate-based polymers.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20060828

Title: Postinflammatory hyperpigmentation: evolving combination treatment strategies.

Journal: Cutis 20060801

Title: Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitis.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20060701

Title: Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical study.

Journal: Ophthalmology 20060601

Title: Dark brown scaly plaques on face and ears.

Journal: The Journal of family practice 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Long-term continuous efalizumab therapy in patients with moderate to severe chronic plaque psoriasis: updated results from an ongoing trial.

Journal: Journal of the American Academy of Dermatology 20060401

Title: Once-daily intranasal corticosteroids for allergic rhinitis. Examining Treatment issues.

Journal: Advance for nurse practitioners 20060401

Title: Expression of TNF-alpha in oral lichen planus treated with fluocinolone acetonide 0.1%.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20060301

Title: Community-based trial of a triple-combination agent for the treatment of facial melasma.

Journal: Cutis 20060301

Title: Efficacy of nebulized flunisolide combined with salbutamol and ipratropium bromide in stable patients with moderate-to-severe chronic obstructive pulmonary disease.

Journal: Respiration; international review of thoracic diseases 20060101

Title: Inhaled flunisolide suppresses the hypothalamic-pituitary-adrenocortical axis, but has minimal systemic immune effects in healthy cats.

Journal: Journal of veterinary internal medicine 20060101

Title: A comprehensive review of the long-term and short-term treatment of melasma with a triple combination cream.

Journal: American journal of clinical dermatology 20060101

Title: Flunisolide decreases exhaled nitric oxide and nitrotyrosine levels in asthmatic children.

Journal: Mediators of inflammation 20060101

Title: Nebulized drug admixtures: effect on aerosol characteristics and albuterol output.

Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20060101

Title: Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: effect of hydrofluoroalkane-flunisolide.

Journal: The Journal of allergy and clinical immunology 20051101

Title: Retisert (Bausch & Lomb/Control Delivery Systems).

Journal: Current opinion in investigational drugs (London, England : 2000) 20051101

Title: Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis.

Journal: Ophthalmology 20050701

Title: The nitrosterols--a step forward from the steroid anti-inflammatory drugs?

Journal: Expert opinion on investigational drugs 20050701

Title: Effects of drug treatment on inflammation and hyperreactivity of airways and on immune variables in cats with experimentally induced asthma.

Journal: American journal of veterinary research 20050701

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20050601

Title: The safety profile of long-term, high-dose intraocular corticosteroid delivery.

Journal: American journal of ophthalmology 20050301

Title: Steroids for choroidal neovascularization.

Journal: American journal of ophthalmology 20050301

Title: Photochemistry and phototoxicity of fluocinolone 16,17-acetonide.

Journal: Photochemistry and photobiology 20050101

Title: Comparison of the analysis of corticosteroids using different techniques.

Journal: Analytical and bioanalytical chemistry 20050101

Title: Hydroquinone 4%, tretinoin 0.05%, fluocinolone acetonide 0.01%: a safe and efficacious 12-month treatment for melasma.

Journal: Cutis 20050101

Title: Fluocinolone acetonide ophthalmic--Bausch & Lomb: fluocinolone acetonide Envision TD implant.

Journal: Drugs in R&D 20050101

Title: A large 12-month extension study of an 8-week trial to evaluate the safety and efficacy of triple combination (TC) cream in melasma patients previously treated with TC cream or one of its dyads.

Journal: Journal of drugs in dermatology : JDD 20050101

Title: Fluocinolone acetonide topical oil for scalp psoriasis.

Journal: The Journal of dermatological treatment 20041201

Title: Enhanced anti-inflammatory potency of a nitric oxide-releasing derivative of flunisolide: role of nuclear factor-kappaB.

Journal: The Journal of pharmacology and experimental therapeutics 20040901

Title: In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics.

Journal: Allergy 20040901

Title: Ocular pharmacokinetics of fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year period.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040601

Title: Treatment with inhaled flunisolide.

Journal: Chest 20040501

Title: Flunisolide HFA for the treatment of asthma: an old friend reformulated.

Journal: Expert opinion on pharmacotherapy 20040501

Title: A comparative study of punch grafting followed by topical corticosteroid versus punch grafting followed by PUVA therapy in stable vitiligo.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040101

Title: Rationale for the use of topical corticosteroids in melasma.

Journal: Journal of drugs in dermatology : JDD 20040101

Title: Improved quality of life with effective treatment of facial melasma: the pigment trial.

Journal: Journal of drugs in dermatology : JDD 20040101

Title: Utilizing combination therapy to optimize melasma outcomes.

Journal: Journal of drugs in dermatology : JDD 20040101

Title: Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses.

Journal: Proceedings of the American Thoracic Society 20040101

Title: Common hyperpigmentation disorders in adults: Part II. Melanoma, seborrheic keratoses, acanthosis nigricans, melasma, diabetic dermopathy, tinea versicolor, and postinflammatory hyperpigmentation.

Journal: American family physician 20031115

Title: A randomized controlled trial of inhaled flunisolide in the management of acute asthma in children.

Journal: Chest 20030901

Title: Effect of topical nasal corticosteroids on patients with chronic fatigue syndrome and rhinitis.

Journal: The Journal of the American Osteopathic Association 20030901

Title: Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2-year follow-up.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20030701

Title: Effect of HFA-flunisolide on peripheral lung inflammation in asthma.

Journal: The Journal of allergy and clinical immunology 20030701

Title: Efficacy and safety of a new triple-combination agent for the treatment of facial melasma.

Journal: Cutis 20030701

Title: Triple inhaled drug protocol for the treatment of acute severe asthma.

Journal: Chest 20030601

Title: Recurrent oral ulceration.

Journal: SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging 20030601

Title: Fluocinolone acetonide 0.01% in peanut oil: therapy for childhood atopic dermatitis, even in patients who are peanut sensitive.

Journal: Journal of the American Academy of Dermatology 20030401

Title: Evaluation of efficacy and safety of flunisolide hydrofluoroalkane for the treatment of asthma.

Journal: Clinical therapeutics 20030301

Title: Small airway asthma therapy, challenges, and the future.

Journal: Postgraduate medicine 20030201

Title: A curious keloid of the penis.

Journal: Acta dermato-venereologica 20030101

Title: Nasal cellularity in 183 unselected schoolchildren aged 9 to 11 years.

Journal: Pediatrics 20021201

Title: Hematologic abnormalities in recurrent oral ulceration.

Journal: The Southeast Asian journal of tropical medicine and public health 20021201

Title: Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021101

Title: Comparison of high-dose inhaled flunisolide to systemic corticosteroids in severe adult asthma.

Journal: Chest 20021001

Title: Supercritical fluids crystallization of budesonide and flunisolide.

Journal: Pharmaceutical research 20021001

Title: Deciphering the phosphorylation 'code' of the glucocorticoid receptor in vivo.

Journal: The Journal of biological chemistry 20020719

Title: One-year trial on safety and normal linear growth with flunisolide HFA in children with asthma.

Journal: Clinical pediatrics 20020601

Title: Systemic effect comparisons of six inhaled corticosteroid preparations.

Journal: American journal of respiratory and critical care medicine 20020515

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020501

Title: The output of flunisolide from different nebulisers.

Journal: The Journal of pharmacy and pharmacology 20020401

Title: A comparison of methods for assessing hypothalamic-pituitary-adrenal (HPA) axis activity in asthma patients treated with inhaled corticosteroids.

Journal: Journal of clinical pharmacology 20020301

Title: Single-dose study to compare the pharmacokinetics of HFA flunisolide and CFC flunisolide.

Journal: Journal of pharmaceutical sciences 20020201

Title: Therapeutic significance of distal airway inflammation in asthma.

Journal: The Journal of allergy and clinical immunology 20020201

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: Multiple-dose proportionality study of flunisolide hydrofluoroalkane.

Journal: Allergy and asthma proceedings 20020101

Title: Flunisolide HFA.

Journal: American journal of respiratory medicine : drugs, devices, and other interventions 20020101

Title: Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion.

Journal: American journal of respiratory medicine : drugs, devices, and other interventions 20020101

Title: Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3).

Journal: British journal of pharmacology 20011201

Title: Cost analysis of the use of inhaled corticosteroids in the treatment of asthma: a 1-year follow-up.

Journal: Respiratory medicine 20011201

Title: Flunisolide HFA vs flunisolide CFC: pharmacokinetic comparison in healthy volunteers.

Journal: Biopharmaceutics & drug disposition 20011201

Title: Adrenal suppression with inhaled corticosteroids.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101

Title: Suppression of hypothalamic-pituitary-adrenal axis activity with inhaled flunisolide and fluticasone propionate in adult asthma patients.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101

Title: Effective control of asthma with hydrofluoroalkane flunisolide delivered as an extrafine aerosol in asthma patients.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101

Title: Investigation of the allergenicity of a refined peanut oil-containing topical dermatologic agent in persons who are sensitive to peanuts.

Journal: Cutis 20010801

Title: Pharmacokinetics of intranasal corticosteroids.

Journal: The Journal of allergy and clinical immunology 20010701

Title: Improved asthma control after changing from low-to-medium doses of other inhaled corticosteroids to low-dose fluticasone propionate.

Journal: MedGenMed : Medscape general medicine 20010608

Title: Transactivation of RARE and GRE in the cellular response to arsenic.

Journal: Molecular and cellular biochemistry 20010601

Title: e-NO peak versus e-NO plateau values in evaluating e-NO production in steroid-naive and in steroid-treated asthmatic children and in detecting response to inhaled steroid treatment.

Journal: Pediatric pulmonology 20010101

Title: [Antiinflammatory effect of a topical corticosteroid: known brand versus generic drug].

Journal: Gaceta medica de Mexico 20010101

Title: Deposition and pharmacokinetics of flunisolide delivered from pressurized inhalers containing non-CFC and CFC propellants.

Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20010101

Title: Corticosteroids administered by nebulization to children with bronchial asthma.

Journal: Advances in therapy 20010101

Title: Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device.

Journal: Investigative ophthalmology & visual science 20001001

Title: Modulation of interleukin-1 alpha mRNA expression in mouse epidermis by tumor promoters and antagonists.

Journal: Molecular carcinogenesis 19930101

Title: Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters.

Journal: Cancer research 19871201

Title: Comparison of amcinonide ointment 0.1 percent twice daily and fluocinonide ointment 0.05 percent three times daily in the treatment of psoriasis.

Journal: Cutis 19830501

Title: Treatment of psoriasis with amcinonide 0.1 percent and fluocinonide 0.05 percent ointments. A comparative double-blind study.

Journal: Cutis 19820601

Title: Corticosteroid-induced cutaneous atrophy and telangiectasia. Experimental production associated with weight loss in rats.

Journal: Archives of dermatology 19760801

Title: The treatment of steroid-induced rosacea and perioral dermatitis.

Journal: Dermatologica 19760101

Title: Steroid rosacea.

Journal: Archives of dermatology 19741001

Title: Iatrogenic dermatitis.

Journal: British medical journal 19691004

Title: Adverse effect of topical fluorinated corticosteroids in rosacea.

Journal: British medical journal 19690315

Title: http://en.wikipedia.org/wiki/Fluocinolone_acetonide

Title: Nehme, A., et al., Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. BMC Med Genomics, 2009. 2: p. 58.

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Tags:67-73-2 Molecular Formula|67-73-2 MDL|67-73-2 SMILES|67-73-2 Fluocinolone acetonide