[1]Grivas,Spiros;Tian,Wei;Ronne,Erik;Lindstroem,Stefan;Olsson,Kjell[ActaChemicaScandinavica,1993,vol.47,#5,p.521-528]
Title: Role of human sulfotransferase 1A1 and N-acetyltransferase 2 in the metabolic activation of 16 heterocyclic amines and related heterocyclics to genotoxicants in recombinant V79 cells.
Journal: Archives of toxicology 20170901
Title: Aryl hydrocarbon receptor activation and CYP1A induction by cooked food-derived carcinogenic heterocyclic amines in human HepG2 cell lines.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20161101
Title: Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor.
Journal: Oncogene 20131010
Title: DNA adducts of the tobacco carcinogens 2-amino-9H-pyrido[2,3-b]indole and 4-aminobiphenyl are formed at environmental exposure levels and persist in human hepatocytes.
Journal: Chemical research in toxicology 20130916
Title: Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901
Title: Flumequine enhances the in vivo mutagenicity of MeIQx in the mouse liver.
Journal: Archives of toxicology 20130801
Title: Lack of Hepatocarcinogenicity of Combinations of Low Doses of 2-amino-3, 8-dimethylimidazo[4,5- f ]quinoxaline and Diethylnitrosamine in Rats: Indication for the Existence of a Threshold for Genotoxic Carcinogens.
Journal: Journal of toxicologic pathology 20120901
Title: Response surface optimization of effects of some processing variables on carcinogenic/mutagenic heterocyclic aromatic amine (HAA) content in cooked patties.
Journal: Meat science 20120701
Title: Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer.
Journal: Carcinogenesis 20120701
Title: Plant extracts, spices, and essential oils inactivate Escherichia coli O157:H7 and reduce formation of potentially carcinogenic heterocyclic amines in cooked beef patties.
Journal: Journal of agricultural and food chemistry 20120411
Title: Occurrence of heterocyclic amines in cooked meat products.
Journal: Meat science 20120301
Title: Protective effects of xanthohumol against the genotoxicity of heterocyclic aromatic amines MeIQx and PhIP in bacteria and in human hepatoma (HepG2) cells.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301
Title: Cytochrome P450-mediated metabolism and DNA binding of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline and its carcinogenic isomer 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in mice.
Journal: Chemical research in toxicology 20120220
Title: Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
Journal: Toxicology and applied pharmacology 20120115
Title: Pancreatic cancer risk: associations with meat-derived carcinogen intake in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort.
Journal: Molecular carcinogenesis 20120101
Title: Heterocyclic aromatic amine [HCA] intake and prostate cancer risk: effect modification by genetic variants.
Journal: Nutrition and cancer 20120101
Title: Formation of heterocyclic amines during cooking of duck meat.
Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Title: Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone.
Journal: The Journal of toxicological sciences 20120101
Title: Well-done meat intake and meat-derived mutagen exposures in relation to breast cancer risk: the Nashville Breast Health Study.
Journal: Breast cancer research and treatment 20111001
Title: In vitro mutagen binding and antimutagenic activity of human Lactobacillus rhamnosus 231.
Journal: Anaerobe 20111001
Title: Inhibitory activity of Asian spices on heterocyclic amines formation in cooked beef patties.
Journal: Journal of food science 20111001
Title: Anti-genotoxic activity of Vitis coignetiae Pulliat towards heterocyclic amines and isolation and identification of caftaric acid as an antimutagenic component from the juice.
Journal: Mutation research 20110816
Title: [Simultaneous determination of 9 heterocyclic aromatic amine in poultry products by solid-phase extraction-high performance liquid chromatography].
Journal: Se pu = Chinese journal of chromatography 20110801
Title: Meat consumption and risk of esophageal and gastric cancer in a large prospective study.
Journal: The American journal of gastroenterology 20110301
Title: Ultraperformance liquid chromatography-tandem mass spectrometry method for biomonitoring cooked meat carcinogens and their metabolites in human urine.
Journal: Analytical chemistry 20110201
Title: No effect of meat, meat cooking preferences, meat mutagens or heme iron on lung cancer risk in the prostate, lung, colorectal and ovarian cancer screening trial.
Journal: International journal of cancer 20110115
Title: Effects of (+)-catechin and (-)-epicatechin on heterocyclic amines-induced oxidative DNA damage.
Journal: Journal of applied toxicology : JAT 20110101
Title: Intake of heterocyclic aromatic amines and the risk of prostate cancer in the EPIC-Heidelberg cohort.
Journal: Cancer causes & control : CCC 20110101
Title: New short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats.
Journal: Cancer informatics 20110101
Title: Impact of meat consumption, preparation, and mutagens on aggressive prostate cancer.
Journal: PloS one 20110101
Title: Preferential induction of the AhR gene battery in HepaRG cells after a single or repeated exposure to heterocyclic aromatic amines.
Journal: Toxicology and applied pharmacology 20101115
Title: Capillary liquid chromatography with diode array and mass spectrometry detection for heterocyclic aromatic amine determination in ready-to-eat food treated with electron-beam irradiation.
Journal: Journal of chromatography. A 20101022
Title: Enhancing effects of carbon tetrachloride on in vivo mutagenicity in the liver of mice fed 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Journal: The Journal of toxicological sciences 20101001
Title: Effects of co-treatment of dextran sulfate sodium and MeIQx on genotoxicity and possible carcinogenicity in the colon of p53-deficient mice.
Journal: The Journal of toxicological sciences 20101001
Title: Association of meat and fat intake with liver disease and hepatocellular carcinoma in the NIH-AARP cohort.
Journal: Journal of the National Cancer Institute 20100908
Title: Naturally occurring food toxins.
Journal: Toxins 20100901
Title: Dietary exposure to heterocyclic amines in high-temperature cooked meat and fish in Malaysia.
Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100801
Title: Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.
Journal: Toxicology and applied pharmacology 20100601
Title: 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis is not enhanced by CYP1A inducers, alpha- and beta-naphthoflavone: relationship to intralobular distribution of CYP1A expression.
Journal: Toxicologic pathology 20100601
Title: Determination of heterocyclic amines in urine samples by capillary liquid chromatography with evaporated light-scattering detection.
Journal: Analytical and bioanalytical chemistry 20100501
Title: Meat mutagens and breast cancer in postmenopausal women--a cohort analysis.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100501
Title: A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
Journal: Chemical research in toxicology 20100419
Title: A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association.
Journal: Cancer research 20100315
Title: Inhibition of heterocyclic amine formation in beef patties by ethanolic extracts of rosemary.
Journal: Journal of food science 20100301
Title: Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).
Journal: Mutation research 20100203
Title: Carcinogenic risk assessment: are there dose thresholds for carcinogens?
Journal: Asian Pacific journal of cancer prevention : APJCP 20100101
Title: A review and meta-analysis of prospective studies of red and processed meat intake and prostate cancer.
Journal: Nutrition journal 20100101
Title: Molecular analysis of carcinogen-induced rodent lung tumors: Involvement of microRNA expression and Krαs or Egfr mutations.
Journal: Molecular medicine reports 20100101
Title: Different threshold levels for 2-amino-3,8 dimethylimidazo[4,5-f]quinoxaline (MelQx) initiation of lung and colon carcinogenesis and the effects of an additional initiation by 4 (methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mice.
Journal: Molecular medicine reports 20100101
Title: Hollow fibre-supported liquid membrane extraction and LC-MS/MS detection for the analysis of heterocyclic amines in urine samples.
Journal: Molecular nutrition & food research 20091201
Title: Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20091101
Title: Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitro.
Journal: European journal of nutrition 20091001
Title: Lack of Modifying Effects of Intratracheal Instillation of Quartz or Dextran Sulfate Sodium (DSS) in Drinking Water on Lung Tumor Development Initiated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Female A/J Mice.
Journal: Journal of toxicologic pathology 20090901
Title: Biomonitoring of carcinogenic heterocyclic aromatic amines in hair: a validation study.
Journal: Chemical research in toxicology 20090817
Title: Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Journal: British journal of cancer 20090707
Title: Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090701
Title: Dietary meat intake in relation to colorectal adenoma in asymptomatic women.
Journal: The American journal of gastroenterology 20090501
Title: Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer.
Journal: Cancer research 20090301
Title: Ethanol Does Not Promote MeIQx-initiated Rat Colon Carcinogenesis Based on Evidence from Analysis of a Colon Cancer Surrogate Marker.
Journal: Journal of toxicologic pathology 20090301
Title: Intakes of red meat, processed meat, and meat mutagens increase lung cancer risk.
Journal: Cancer research 20090201
Title: Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer.
Journal: Analytical chemistry 20090115
Title: Short term exposure to cooking fumes and pulmonary function.
Journal: Journal of occupational medicine and toxicology (London, England) 20090101
Title: Optimized HPLC method for analysis of polar and nonpolar heterocyclic amines in cooked meat products.
Journal: Journal of AOAC International 20090101
Title: Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers.
Journal: Nutrition journal 20090101
Title: Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan.
Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20090101
Title: Enhancing effects of a high fat diet on 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced lung tumorigenesis in female A/J mice.
Journal: Molecular medicine reports 20090101
Title: Effect of beer/red wine marinades on the formation of heterocyclic aromatic amines in pan-fried beef.
Journal: Journal of agricultural and food chemistry 20081126
Title: Modifying effects of chitin, chitosan and their related compounds on 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in a rat medium-term hepatocarcinogenesis model, and their post-initiation effects in a female rat 2-stage multi-organ carcinogenesis model.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080801
Title: Quantification of heterocyclic aromatic amines in fried meat by HPTLC/UV-FLD and HPLC/UV-FLD: a comparison of two methods.
Journal: Journal of agricultural and food chemistry 20080625
Title: Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080601
Title: Carcinogenic risk of heterocyclic amines in combination - assessment with a liver initiation model.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601
Title: Suppressive effect of poly-gamma-glutamate on SOS response of Salmonella typhimurium induced by chemical mutagens.
Journal: Journal of bioscience and bioengineering 20080601
Title: Evidence of a threshold-effect for 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline liver carcinogenicity in F344/DuCrj rats.
Journal: Toxicologic pathology 20080401
Title: Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial.
Journal: Molecular nutrition & food research 20080301
Title: Modification by N-acetyltransferase 1 genotype on the association between dietary heterocyclic amines and colon cancer in a multiethnic study.
Journal: Mutation research 20080201
Title: Occurrence of mutations in the epidermal growth factor receptor gene in X-ray-induced rat lung tumors.
Journal: Cancer science 20080201
Title: Quantitation of 13 heterocyclic aromatic amines in cooked beef, pork, and chicken by liquid chromatography-electrospray ionization/tandem mass spectrometry.
Journal: Journal of agricultural and food chemistry 20080109
Title: Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101
Title: Effect of oil marinades with garlic, onion, and lemon juice on the formation of heterocyclic aromatic amines in fried beef patties.
Journal: Journal of agricultural and food chemistry 20071212
Title: Inhibitory effect of fruit extracts on the formation of heterocyclic amines.
Journal: Journal of agricultural and food chemistry 20071212
Title: What is a practical threshold?
Journal: Toxicologic pathology 20071001
Title: Meat intake, preparation methods, mutagens and colorectal adenoma recurrence.
Journal: Carcinogenesis 20070901
Title: Inhibitory activities of dietary phenolic compounds on heterocyclic amine formation in both chemical model system and beef patties.
Journal: Molecular nutrition & food research 20070801
Title: Tobacco smoking and urinary levels of 2-amino-9H-pyrido[2,3-b]indole in men of Shanghai, China.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070801
Title: Processed meat intake, CYP2A6 activity and risk of colorectal adenoma.
Journal: Carcinogenesis 20070601
Title: Heterocyclic amines in griddled beef steak analysed using a single extract clean-up procedure.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070401
Title: Analysis of gene expression in different stages of MeIQx-induced rat hepatocarcinogenesis.
Journal: Oncology reports 20070401
Title: Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens.
Journal: Toxicologic pathology 20070401
Title: Enhancement of phase II enzyme activity by purpurin resulting in the suppression of MeIQx-DNA-adduct formation in mice.
Journal: Mutation research 20070110
Title: Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.
Journal: International journal of cancer 20060901
Title: Differential effects of heterocyclic amines on poly(ADP-ribose) polymerase-1 and mono-ADP-ribosyltransferase A.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060901
Title: Existence of a no effect level for MeIQx hepatocarcinogenicity on a background of thioacetamide-induced liver damage in rats.
Journal: Cancer science 20060601
Title: Meat mutagens and risk of distal colon adenoma in a cohort of U.S. men.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060601
Title: Chemical synthesis of 2'-deoxyguanosine-C8 adducts with heterocyclic amines: an application to synthesis of oligonucleotides site-specifically adducted with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Journal: Chemical research in toxicology 20060601
Title: N-acetylcysteine and S-methylcysteine inhibit MeIQx rat hepatocarcinogenesis in the post-initiation stage.
Journal: Carcinogenesis 20060501
Title: Influence of lignification and feruloylation of maize cell walls on the adsorption of heterocyclic aromatic amines.
Journal: Journal of agricultural and food chemistry 20060308
Title: Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) rat hepatocarcinogenesis by caffeine, a CYP1A2 inducer, points to complex counteracting influences.
Journal: Cancer letters 20060208
Title: Stability and reactivity of 2-nitrosoamino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Journal: Chemical research in toxicology 20060201
Title: Existence of no-observed effect levels for 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline on hepatic preneoplastic lesion development in BN rats.
Journal: Cancer letters 20060118
Title: Existence of no hepatocarcinogenic effect levels of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline with or without coadministration with ethanol.
Journal: Toxicologic pathology 20060101
Title: A prospective study of meat and meat mutagens and prostate cancer risk.
Journal: Cancer research 20051215
Title: Dose-dependence of promotion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis by ethanol: evidence for a threshold.
Journal: Cancer science 20051101
Title: Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025
Title: Novel antimutagenic factors derived from the edible mushroom Agrocybe cylindracea.
Journal: Mutation research 20051003
Title: PhIP carcinogenicity in breast cancer: computational and experimental evidence for competitive interactions with human estrogen receptor.
Journal: Chemical research in toxicology 20051001
Title: Meat, meat cooking methods and preservation, and risk for colorectal adenoma.
Journal: Cancer research 20050901
Title: Suppression of glutathione S-transferase placental form-positive foci development in rat hepatocarcinogenesis by Chlorella pyrenoidosa.
Journal: Oncology reports 20050801
Title: Nitric oxide-mediated nitrosation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline potentiated by hemin and myeloperoxidase.
Journal: Chemical research in toxicology 20050601
Title: Quantitation of carcinogenic heterocyclic aromatic amines and detection of novel heterocyclic aromatic amines in cooked meats and grill scrapings by HPLC/ESI-MS.
Journal: Journal of agricultural and food chemistry 20050420
Title: Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050401
Title: Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study.
Journal: Carcinogenesis 20050301
Title: Formation of a mutagenic heterocyclic aromatic amine from creatinine in urine of meat eaters and vegetarians.
Journal: Chemical research in toxicology 20050301
Title: Inhibitory effects of heterocyclic amine-induced DNA adduct formation in mouse liver and lungs by beer.
Journal: Journal of agricultural and food chemistry 20050209
Title: A comparison of genotoxicity between three common heterocyclic amines and acrylamide.
Journal: Mutation research 20050207
Title: Gene expression profiling of chemically induced rat mammary gland cancer.
Journal: Carcinogenesis 20050201
Title: Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cyclooxygenase-2 and inducible nitric oxide synthase.
Journal: Carcinogenesis 20050101
Title: Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer.
Journal: Prostate cancer and prostatic diseases 20050101
Title: Dietary exposure to heterocyclic amines in a Chinese population.
Journal: Nutrition and cancer 20050101
Title: Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
Journal: Toxicologic pathology 20050101
Title: Addition of various carbohydrates to beef burgers affects the formation of heterocyclic amines during frying.
Journal: Journal of agricultural and food chemistry 20041215
Title: The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity.
Journal: Carcinogenesis 20041201
Title: Induction of DNA-adducts and increase of 8-hydroxy-2-deoxyguanosine, but no development of preneoplastic lesions in offspring liver with transplacental and trans-breast milk exposure to 2-amino-3,8-dimethylimidazo [4,5-f ]quinoxaline (MeIQx) in rats.
Journal: Cancer science 20041201
Title: Lactoperoxidase-catalyzed activation of carcinogenic aromatic and heterocyclic amines.
Journal: Chemical research in toxicology 20041201
Title: Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2.
Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20041101
Title: Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens.
Journal: Archives of toxicology 20041001
Title: No-observed effect levels for carcinogenicity and for in vivo mutagenicity of a genotoxic carcinogen.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041001
Title: Heterocyclic amines in some Swedish cooked foods industrially prepared or from fast food outlets and restaurants.
Journal: Molecular nutrition & food research 20040901
Title: Rapid biomonitoring of heterocyclic aromatic amines in human urine by tandem solvent solid phase extraction liquid chromatography electrospray ionization mass spectrometry.
Journal: Chemical research in toxicology 20040801
Title: Randomized controlled trial of dietary intervention: association between level of urinary phenolics and anti-mutagenicity.
Journal: Mutation research 20040711
Title: Modulation of cytochrome P450 1A1 by food-derived heterocyclic aromatic amines.
Journal: Toxicology 20040701
Title: Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice.
Journal: Gastroenterology 20040501
Title: Inhibitory effects of beer on heterocyclic amine-induced mutagenesis and PhIP-induced aberrant crypt foci in rat colon.
Journal: Mutation research 20040411
Title: Determination of heterocyclic aromatic amines (HAs) content in samples of household-prepared meat dishes.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325
Title: Phytoalexin resveratrol attenuates the mutagenicity of the heterocyclic amines 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325
Title: Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system.
Journal: Cancer science 20040201
Title: Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study.
Journal: Breast cancer research : BCR 20040101
Title: Selected heterocyclic amines.
Journal: Report on carcinogens : carcinogen profiles 20040101
Title: Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains.
Journal: Carcinogenesis 20031201
Title: Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse.
Journal: Carcinogenesis 20031201
Title: Low dose genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in gpt delta transgenic mice.
Journal: Mutation research 20031110
Title: Mutagenic activity and heterocyclic amine carcinogens in commercial pet foods.
Journal: Mutation research 20030805
Title: Effect of high water-holding capacity on the formation of heterocyclic amines in fried beefburgers.
Journal: Journal of agricultural and food chemistry 20030716
Title: Post-initiation inhibition of MeIQx hepatocarcinogenesis in rats by cysteine.
Journal: Osaka city medical journal 20030601
Title: Enhancing risk of ethanol on MeIQx-induced rat hepatocarcinogenesis is accompanied with increased levels of cellular proliferation and oxidative stress.
Journal: Cancer letters 20030320
Title: Inhibition of mutagenicity of food-derived heterocyclic amines by sulforaphane--a constituent of broccoli.
Journal: Indian journal of experimental biology 20030301
Title: Lack of initiation activity in rat liver of low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Journal: Cancer letters 20030227
Title: Effects of cigarette smoke and a heterocyclic amine, MeIQx on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver.
Journal: Mutagenesis 20030101
Title: Effect of high sucrose diet on cytochrome P450 1A and heterocyclic amine mutagenesis.
Journal: Anticancer research 20030101
Title: Inhibitory effect of dibenzoylmethane on mutagenicity of food-derived heterocyclic amine mutagens.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20030101
Title: A model system study of the inhibition of heterocyclic aromatic amine formation by organosulfur compounds.
Journal: Journal of agricultural and food chemistry 20021218
Title: Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food.
Journal: Indian journal of experimental biology 20021201
Title: Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis in rats by fenbendazole--a CYP1A2 inducer.
Journal: Cancer letters 20021108
Title: Inhibition of heterocyclic aromatic amine formation in fried ground beef patties by garlic and selected garlic-related sulfur compounds.
Journal: Journal of food protection 20021101
Title: Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin.
Journal: Mutation research 20021031
Title: Development of a short questionnaire to assess the dietary intake of heterocyclic aromatic amines.
Journal: Public health nutrition 20021001
Title: Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine.
Journal: Japanese journal of cancer research : Gann 20021001
Title: Mammary gland carcinogenesis by food-derived heterocyclic amines and studies on the mechanisms of carcinogenesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Journal: Mutation research 20020930
Title: Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk.
Journal: Mutation research 20020930
Title: Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
Journal: Mutation research 20020930
Title: An epidemiologic approach to studying heterocyclic amines.
Journal: Mutation research 20020930
Title: Estimation of dietary HCA intakes in a large-scale population-based prospective study in Japan.
Journal: Mutation research 20020930
Title: Biomarkers of exposure to heterocyclic amines: approaches to improve the exposure assessment.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801
Title: Screening for heterocyclic amines in chicken cooked in various ways.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801
Title: Effects of soy sauce and sugar on the formation of heterocyclic amines in marinated foods.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020701
Title: Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats.
Journal: Japanese journal of cancer research : Gann 20020601
Title: Role of oxidative DNA damage caused by carbon tetrachloride-induced liver injury -- enhancement of MeIQ-induced glutathione S-transferase placental form-positive foci in rats.
Journal: Cancer letters 20020508
Title: Natural variations of precursors in pig meat affect the yield of heterocyclic amines--effects of RN genotype, feeding regime, and sex.
Journal: Journal of agricultural and food chemistry 20020508
Title: Analysis and quantification of DNA adducts of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in liver of rats by liquid chromatography/electrospray tandem mass spectrometry.
Journal: Chemical research in toxicology 20020401
Title: Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas.
Journal: Pharmacogenetics 20020301
Title: Antimutagenicity of Murdannia loriformis in the Salmonella mutation assay and its inhibitory effects on azoxymethane-induced DNA methylation and aberrant crypt focus formation in male F344 rats.
Journal: The journal of medical investigation : JMI 20020201
Title: Human prostate epithelial cells metabolize chemicals of dietary origin to mutagens.
Journal: Cancer letters 20020125
Title: Mutational spectra of benzo[a]pyrene and MeIQx in rpsL transgenic zebrafish embryos.
Journal: Mutation research 20020115
Title: Enhancement by cigarette smoke exposure of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis in close association with elevation of hepatic CYP1A2.
Journal: Japanese journal of cancer research : Gann 20020101
Title: Mutagenicity of food-derived carcinogens and the effect of antioxidant vitamins.
Journal: Nutrition and cancer 20020101
Title: Clean-up procedures for the analysis of heterocyclic aromatic amines (aminoazaarenes) from heat-treated meat samples.
Journal: Journal of chromatography. A 20011214
Title: Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man.
Journal: Carcinogenesis 20010901
Title: Potent antimutagenic activity of white tea in comparison with green tea in the Salmonella assay.
Journal: Mutation research 20010822
Title: Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system.
Journal: Journal of agricultural and food chemistry 20010801
Title: A comparison of whole wheat, refined wheat and wheat bran as inhibitors of heterocyclic amines in the Salmonella mutagenicity assay and in the rat colonic aberrant crypt focus assay.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010701
Title: Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.
Journal: Chemical research in toxicology 20010701
Title: Dietary intake of heterocyclic amines, meat-derived mutagenic activity, and risk of colorectal adenomas.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010501
Title: The food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline: a conformational analysis of its major DNA adduct and comparison with the 2-amino-3-methylimidazo[4,5-f]quinoline adduct.
Journal: Chemical research in toxicology 20010501
Title: Reporter gene transgenic mice as a tool for analyzing the molecular mechanisms underlying experimental carcinogenesis.
Journal: Journal of experimental & clinical cancer research : CR 20010301
Title: Induction of liver preneoplastic lesions by aminophenylnorharman, formed from norharman and aniline, in male F344 rats.
Journal: Cancer letters 20010226
Title: Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.
Journal: Chemical research in toxicology 20010201
Title: Carcinogen substrate specificity of human COX-1 and COX-2.
Journal: Carcinogenesis 20010101
Title: Recombinant human P450 forms 1A1, 1A2, and 1B1 catalyze the bioactivation of heterocyclic amine mutagens in Escherichia coli lacZ strains.
Journal: Environmental and molecular mutagenesis 20010101
Title: Metabolism of the food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes.
Journal: Advances in experimental medicine and biology 20010101
Title: Interspecies differences in metabolism of heterocyclic aromatic amines by rat and human P450 1A2.
Journal: Cancer letters 19990901
Title: Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocylic amines.
Journal: Cancer letters 19990901
Title: Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats.
Journal: Cancer letters 19990901
Title: Heterozygous p53-deficient mice are not susceptible to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) carcinogenicity.
Journal: Cancer letters 19990524
Title: Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocyclic amines.
Journal: Cancer research 19980501
Title: Marmoset CYP1A2: primary structure and constitutive expression in livers.
Journal: Carcinogenesis 19971001
Title: Assessing human risk to heterocyclic amines.
Journal: Mutation research 19970512
Title: Effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on intestinal polyp development in Apc delta 716 knockout mice.
Journal: Molecular carcinogenesis 19960101
Title: Simultaneous expression of human CYP3A7 and N-acetyltransferase in Chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines.
Journal: Archives of biochemistry and biophysics 19950710
Title: Studies on the carcinogenic and myocardial effects of 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in nonhuman primates.
Journal: Princess Takamatsu symposia 19950101
Title: Genetic alterations in HCA-induced tumors.
Journal: Princess Takamatsu symposia 19950101
Title: Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
Journal: Cancer research 19940915
Title: Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines.
Journal: Carcinogenesis 19930901
Title: Enhancement of GST-P positive liver cell foci development by combined treatment of rats with five heterocyclic amines at low doses.
Journal: Carcinogenesis 19910501
Title: Mutational activation of c-Ha-ras gene in squamous cell carcinomas of rat Zymbal gland induced by carcinogenic heterocyclic amines.
Journal: Molecular carcinogenesis 19910101
Title: Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450.
Journal: Cancer research 19900601
Title: Comparison of initiation potential of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in an in vivo carcinogen bioassay system.
Journal: Carcinogenesis 19900401
Title: Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.
Journal: Cancer research 19890615
Title: Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogens.
Journal: Chemico-biological interactions 19880101
Title: Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx.
Journal: Princess Takamatsu symposia 19850101
