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15291-76-6,MFCD06642603
Catalog No.:AA00AOGQ

15291-76-6 | Ginkgolide c

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1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
98% by HPLC
in stock  
$125.00   $88.00
- +
10mg
98% by HPLC
in stock  
$168.00   $117.00
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20mg
in stock  
$227.00   $159.00
- +
25mg
98% by HPLC
in stock  
$283.00   $198.00
- +
50mg
98% by HPLC
in stock  
$436.00   $305.00
- +
100mg
98% by HPLC
in stock  
$708.00   $495.00
- +
500mg
98% by HPLC
in stock  
$2,141.00   $1,499.00
- +
1000mg
98% by HPLC
in stock  
$3,388.00   $2,371.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AOGQ
Chemical Name:
Ginkgolide c
CAS Number:
15291-76-6
Molecular Formula:
C20H24O11
Molecular Weight:
440.3980
MDL Number:
MFCD06642603
SMILES:
O=C1O[C@@H]2[C@@]([C@@H]1C)(O)[C@@]13[C@]4([C@@H]2O)[C@H](OC3=O)[C@@H]([C@H]([C@@]24[C@H](O1)OC(=O)[C@@H]2O)C(C)(C)C)O
Properties
Computed Properties
 
Complexity:
957  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
12  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
1  
XLogP3:
-1.4  

Literature

Title: Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.

Journal: Magnetic resonance in chemistry : MRC 20120801

Title: Spectroscopic investigation of Ginkgo biloba terpene trilactones and their interaction with amyloid peptide Abeta(25-35).

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

Title: Simultaneous determination of ginkgolides A, B, C and bilobalide in plasma by LC-MS/MS and its application to the pharmacokinetic study of Ginkgo biloba extract in rats.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315

Title: Ginkgolide C inhibits platelet aggregation in cAMP- and cGMP-dependent manner by activating MMP-9.

Journal: Biological & pharmaceutical bulletin 20071201

Title: Single-laboratory validation for the determination of terpene lactones in Ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography with evaporative light-scattering detection.

Journal: Journal of AOAC International 20070101

Title: Validation of capillary gas chromatographic method for determination of bilobalide and ginkgolides A, B, C in Ginkgo biloba dry and liquid extracts.

Journal: Acta poloniae pharmaceutica 20070101

Title: LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.

Journal: Journal of pharmaceutical and biomedical analysis 20060224

Title: [Quantitative determination of ginkgolides by liquid chromatography-electrospray mass spectrometry].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

Title: [Applications of two-dimensional liquid chromatography coupled to mass spectrometry for the separation and identification of compounds in ginkgo biloba extracts].

Journal: Se pu = Chinese journal of chromatography 20050101

Title: Preparation of a tritiated ginkgolide.

Journal: Bioorganic & medicinal chemistry letters 20041115

Title: Isolation of ginkgolides A, B, C, J and bilobalide from G. biloba extracts.

Journal: Phytochemistry 20041101

Title: A method for extraction and quantification of Ginkgo terpene trilactones.

Journal: Analytical chemistry 20040801

Title: Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1beta2gamma2L GABAA receptors.

Journal: European journal of pharmacology 20040628

Title: Ginkgolides and glycine receptors: a structure-activity relationship study.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040319

Title: Effect of Ginkgo biloba extract on rat hepatic microsomal CYP1A activity: role of ginkgolides, bilobalide, and flavonols.

Journal: Canadian journal of physiology and pharmacology 20040101

Title: An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.

Journal: Journal of natural products 20031001

Title: Quantitative analysis of bilobalide and ginkgolides from Ginkgo biloba leaves and Ginkgo products using (1)H-NMR.

Journal: Chemical & pharmaceutical bulletin 20030201

Title: Identification and the retention index of bilobalide and ginkgolides using capillary gas chromatography.

Journal: Journal of chromatographic science 20021001

Title: Ginkgolide derivatives for photolabeling studies: preparation and pharmacological evaluation.

Journal: Journal of medicinal chemistry 20020829

Title: Ginkgolides: selective acetylations, translactonization, and biological evaluation.

Journal: The Journal of organic chemistry 20020628

Title: Three ginkgolide hydrates from Ginkgo biloba L.: ginkgolide A monohydrate, ginkgolide C sesquihydrate and ginkgolide J dihydrate, all determined at 120 K.

Journal: Acta crystallographica. Section C, Crystal structure communications 20020301

Title: Liou CJ, et al. Ginkgolide C Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway. Evid Based Complement Alternat Med. 2015;2015:298635.

Title: Ginkgolide C, et al. Ginkgolide C inhibits platelet aggregation in cAMP- and cGMP-dependent manner by activating MMP-9. Biol Pharm Bull. 2007 Dec;30(12):2340-4.

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